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Chunk #19 — RESULTS — Effects of ethanol on gene expression

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Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression.
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There were 567 probe sets, representing 478 unique named genes, that differed in expression between cell lines derived from alcoholics and cell lines from non-alcoholics (at an FDR ≤ 36%, nominal p-value ≤ 0.0076; Figure 2). 64% of the genes that differed by phenotype were also affected by ethanol treatment (305 genes) compared to 51% of named genes being affected by ethanol. Supplementary Table 2 lists the genes differentially expressed between alcoholics and controls.