Further, low P3 and low FT are prevalent in families densely affected with AUD, including among offspring, indicating neurocognitive deficits and vulnerability to develop AUD and related disorders. However, given that environmental factors may buffer against this neural liability, this study is uniquely positioned to examine the role of parent–child closeness during adolescence in fostering normal cognitive development and buffering against developing AUD in these high-risk offspring. Accordingly, the goals of this study are to (1) examine the associations of closeness with mother and father during adolescence with target-related parietal P3 amplitude, target-related FT power, and binge drinking in high-risk offspring and (2) to examine differences in these associations as a function of offspring sex. We hypothesized that greater parent–child closeness during adolescence is associated with larger target-related parietal P3 amplitude, higher FT power, and less binge drinking in offspring. We also hypothesized that these associations would vary by offspring sex.
