devices where microfabrication and microfluidic technology are combined to support organoid culture and fluid flow, enabling high-throughput testing, environmental sampling, and biosensing (Skardal et al., 2016). These technologies are currently being explored in a range of tissue types and could have significant impact in medicine if attention is paid to functional differentiation and integrity of form and function maintainance. At such time, these will be ready to be implemented not only in drug discovery but also in patient treatment. The future will improve multi-organoid systems, also referred to as “body on a chip,” developing systems of increased biological complexity, where multiple organoids derived from different tissues are brought together and allowed to integrate (Maschmeyer et al., 2015a,b).
