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Chunk #35 — Use of iPSCs to model neurodegenerative diseases — iPSCs and amyotrophic lateral sclerosis

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Modeling Human Neurological and Neurodegenerative Diseases: From Induced Pluripotent Stem Cells to Neuronal Differentiation and Its Applications in Neurotrauma.
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Up till now, FDA has only approved one drug, riluzole, for ALS which acts by delaying progression of the disease but has no assertive efficacy in increasing survival (Cheah et al., 2010). This authenticates the importance of iPS cell technology in providing a ray of hope for those patients who continue to suffer the lack of an effective remedy for their condition.