Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies.
paper
Cited
Public
Unavailable
- Authors
- Sullivan, Patrick F; Kendler, Kenneth S; Neale, Michael C
- Year
- 2003
- Journal
- Archives of general psychiatry
- PMID
- 14662550
- DOI
- 10.1001/archpsyc.60.12.1187
CONTEXT: There are many published twin studies of schizophrenia. Although these studies have been reviewed previously, to our knowledge, no review has provided quantitative summary estimates of the impact of genes and environment on liability to schizophrenia that also accounted for the different ascertainment strategies used. OBJECTIVE: To calculate meta-analytic estimates of heritability in liability and shared and individual-specific environmental effects from the pooled twin data. DATA SOURCES: We used a structured literature search to identify all published twin studies of schizophrenia, including MEDLINE, dissertation, and books-in-print searches. STUDY SELECTION: Of the 14 identified studies, 12 met the minimal inclusion criteria of systematic ascertainment. DATA SYNTHESIS: By using a multigroup twin model, we found evidence for substantial additive genetic effects-the point estimate of heritability in liability to schizophrenia was 81% (95% confidence interval, 73%-90%). Notably, there was consistent evidence across these studies for common or shared environmental influences on liability to schizophrenia-joint estimate, 11% (95% confidence interval, 3%-19%). CONCLUSIONS: Despite evidence of heterogeneity across studies, these meta-analytic results from 12 published twin studies of schizophrenia are consistent with a view of schizophrenia as a complex trait that results from genetic and environmental etiological influences. These results are broadly informative in that they provide no information about the specific identity of these etiological influences, but they do provide a component of a unifying empirical basis supporting the rationality of searches for underlying genetic and common environmental etiological factors.
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| Impact of clozapine on the expression of miR-675-3p in plasma exosomes derived from patients with schizophrenia. | Funahashi Y et al. | โ | 2023 | โ |
| Impact of Early-Life Factors on Risk for Schizophrenia and Bipolar Disorder. | Robinson N et al. | โ | 2023 | โ |
| Impaired mnemonic discrimination in children and adolescents at risk for schizophrenia. | ฤฐmamoฤlu A et al. | โ | 2023 | โ |
| Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia. | Huang YC et al. | โ | 2023 | โ |
| Inferring disease architecture and predictive ability with LDpred2-auto. | Privรฉ F et al. | โ | 2023 | โ |
| In memory of Professor Iain Wilkinson: cognitive and neuroimaging endophenotypes in a consanguineous schizophrenia multiplex family. | Wilkinson ID et al. | โ | 2023 | โ |
| Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder. | Johnson EC et al. | โ | 2023 | โ |
| Lessons Learned From Parsing Genetic Risk for Schizophrenia Into Biological Pathways. | Pergola G et al. | โ | 2023 | โ |
| miR-9-5p deficiency contributes to schizophrenia. | Fu X et al. | โ | 2023 | โ |
| Mitochondrial DNA Copy Number and Heteroplasmy in Monozygotic Twins Discordant for Schizophrenia. | Win PW et al. | โ | 2023 | โ |
| Mitochondrial genetic variants associated with bipolar disorder and Schizophrenia in a Japanese population. | Tachi R et al. | โ | 2023 | โ |
| Molecular mechanisms of schizophrenia: Insights from human genetics. | Farsi Z et al. | โ | 2023 | โ |
| Molecules Affecting Brain Development and Nervous System. | Nakadate K et al. | โ | 2023 | โ |
| MR-DoC2: Bidirectional Causal Modeling with Instrumental Variables and Data from Relatives. | Castro-de-Araujo LFS et al. | โ | 2023 | โ |
| Neurodevelopmental disturbances in schizophrenia: evidence from genetic and environmental factors. | Schmitt A et al. | โ | 2023 | โ |
| New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications. | Andreassen OA et al. | โ | 2023 | โ |
| Pharmaco-genetic analysis of <i>CYP1A1</i> and <i>RGS4</i> variants and its impact on response to olanzapine and risperidone in Indian schizophrenic cohort. | Garg R et al. | โ | 2023 | โ |
| Polygenic risk, familial liability and stress reactivity in psychosis: an experience sampling study. | Schick A et al. | โ | 2023 | โ |
| Polygenic risk scores for schizophrenia are associated with oculomotor endophenotypes. | Coors A et al. | โ | 2023 | โ |
| Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia. | Wen J et al. | โ | 2023 | โ |
| Recent advances in dopamine D<sub>2</sub> receptor ligands in the treatment of neuropsychiatric disorders. | Juza R et al. | โ | 2023 | โ |
| Rediscovering tandem repeat variation in schizophrenia: challenges and opportunities. | Birnbaum R | โ | 2023 | โ |
| Schizophrenia, Human Leukocyte Antigen (HLA), and Herpes Viruses: Immunogenetic Associations at the Population Level. | James LM et al. | โ | 2023 | โ |
| Schizophrenia polygenic risk score and type 2 diabetes onset in older adults with no schizophrenia diagnosis. | Shamsutdinova D et al. | โ | 2023 | โ |
| Significance of an altered lncRNA landscape in schizophrenia and cognition: clues from a case-control association study. | Mukhopadhyay A et al. | โ | 2023 | โ |
| Single-Nuclei RNA Sequencing of 5 Regions of the Human Prenatal Brain Implicates Developing Neuron Populations in Genetic Risk for Schizophrenia. | Cameron D et al. | โ | 2023 | โ |
| Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study. | Rogdaki M et al. | โ | 2023 | โ |
| Study protocol of the Berlin Research Initiative for Diagnostics, Genetics and Environmental Factors in Schizophrenia (BRIDGE-S). | Braun A et al. | โ | 2023 | โ |
| Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants. | McAfee JC et al. | โ | 2023 | โ |
| The contribution of copy number variants to psychiatric symptoms and cognitive ability. | Mollon J et al. | โ | 2023 | โ |
| The future of diagnosis in clinical neurosciences: Comparing multiple sclerosis and schizophrenia. | Misiak B et al. | โ | 2023 | โ |
| The genetic architecture of schizophrenia: review of large-scale genetic studies. | Kato H et al. | โ | 2023 | โ |
| The Hypothalamic-Pituitary-Gonadal Axis in Men with Schizophrenia. | Matuszewska A et al. | โ | 2023 | โ |
| The molecular pathology of schizophrenia: an overview of existing knowledge and new directions for future research. | Nakamura T et al. | โ | 2023 | โ |
| Whole Genome Sequencing Revealed Inherited Rare Oligogenic Variants Contributing to Schizophrenia and Major Depressive Disorder in Two Families. | Chung IH et al. | โ | 2023 | โ |
| YBX1-Mediated DNA Methylation-Dependent SHANK3 Expression in PBMCs and Developing Cortical Interneurons in Schizophrenia. | Ni P et al. | โ | 2023 | โ |
| A comparative study to determine the association of gut microbiome with schizophrenia in Zhejiang, China. | Yan F et al. | โ | 2022 | โ |
| A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy. | Athanasiadis G et al. | โ | 2022 | โ |
| Adolescent Verbal Memory as a Psychosis Endophenotype: A Genome-Wide Association Study in an Ancestrally Diverse Sample. | Wang B et al. | โ | 2022 | โ |
| A family study on first episode of psychosis patients: Exploring neuropsychological performance as an endophenotype. | Murillo-Garcรญa N et al. | โ | 2022 | โ |
| A functional neuroimaging association study on the interplay between two schizophrenia genome-wide associated genes (CACNA1C and ZNF804A). | Guardiola-Ripoll M et al. | โ | 2022 | โ |
| Age at Separation of Twin Pairs in the FinnTwin12 Study. | Wang Z et al. | โ | 2022 | โ |
| Altered Intestinal Permeability Biomarkers in Schizophrenia: A Possible Link with Subclinical Inflammation. | Gokulakrishnan K et al. | โ | 2022 | โ |
| Alternative Therapy of Psychosis: Potential Phytochemicals and Drug Targets in the Management of Schizophrenia. | Saleem A et al. | โ | 2022 | โ |
| An alternative splicing hypothesis for neuropathology of schizophrenia: evidence from studies on historical candidate genes and multi-omics data. | Zhang CY et al. | โ | 2022 | โ |
| Association Between Childhood Exposure to Pet Cats and Later Diagnosis of Schizophrenia: A Case-Control Study in Saudi Arabia. | Hakami RM et al. | โ | 2022 | โ |
| Association between MTHFR (677C>T and 1298A>C) polymorphisms and psychiatric disorder: A meta-analysis. | Meng X et al. | โ | 2022 | โ |
| Associations between polygenic risk scores and amplitude of low-frequency fluctuation of inferior frontal gyrus in schizophrenia. | Kang J et al. | โ | 2022 | โ |
| Autism spectrum disorder and schizophrenia: An updated conceptual review. | Jutla A et al. | โ | 2022 | โ |
| Brain structural abnormalities of the associative striatum in adolescents and young adults at genetic high-risk of schizophrenia: Implications for illness endophenotypes. | Nestor PG et al. | โ | 2022 | โ |
| Cannabinoid receptor gene polymorphisms and cognitive performance in patients with schizophrenia and controls. | Ferretjans R et al. | โ | 2022 | โ |
| Cell type-specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis. | Chen R et al. | โ | 2022 | โ |
| Common Genetic Variation and Age of Onset of Anorexia Nervosa. | Watson HJ et al. | โ | 2022 | โ |
| Concerns about the use of polygenic embryo screening for psychiatric and cognitive traits. | Lencz T et al. | โ | 2022 | โ |
| Deregulatory miRNA-BDNF Network Inferred from Dynamic Expression Changes in Schizophrenia. | Fu X et al. | โ | 2022 | โ |
| Derivation and utility of schizophrenia polygenic risk associated multimodal MRI frontotemporal network. | Qi S et al. | โ | 2022 | โ |
| Development of the Korea-Polyenvironmental Risk Score for Psychosis. | Jeon EJ et al. | โ | 2022 | โ |
| Differences in subcortical brain volumes among patients with schizophrenia and bipolar disorder and healthy controls. | Ohi K et al. | โ | 2022 | โ |
| Distinctively lower DISC1 mRNA levels in patients with schizophrenia, especially in those with higher positive, negative, and depressive symptoms. | Chen YM et al. | โ | 2022 | โ |
| DNA Banking to Assess Genetic Influences on Schizophrenia. | Sadighi G et al. | โ | 2022 | โ |
| DNA Methylation Markers and Prediction Model for Depression and Their Contribution for Breast Cancer Risk. | Wang N et al. | โ | 2022 | โ |
| Effect of schizophrenia risk gene polymorphisms on cognitive and neural plasticity. | Zhao W et al. | โ | 2022 | โ |
| Effects of polygenic risk for major mental disorders and cross-disorder on cortical complexity. | Schmitt S et al. | โ | 2022 | โ |
| Effects of psychosis-associated genetic markers on brain volumetry: a systematic review of replicated findings and an independent validation. | Vouga Ribeiro N et al. | โ | 2022 | โ |
| Embedded figures in schizophrenia: A main deficit but no specificity. | Favrod O et al. | โ | 2022 | โ |
| Functional characterization of the schizophrenia associated gene AS3MT identifies a role in neuronal development. | Washer SJ et al. | โ | 2022 | โ |
| Functional variant rs2270363 on 16p13.3 confers schizophrenia risk by regulating NMRAL1. | Wang J et al. | โ | 2022 | โ |
| Gene-Environment Correlation over Time: A Longitudinal Analysis of Polygenic Risk Scores for Schizophrenia and Major Depression in Three British Cohorts Studies. | Machlitt-Northen S et al. | โ | 2022 | โ |
| Gene expression changes following chronic antipsychotic exposure in single cells from mouse striatum. | Abrantes A et al. | โ | 2022 | โ |
| Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci. | Wistrรถm ED et al. | โ | 2022 | โ |
| Genome-wide association studies-supported rs12966547 variant of the long noncoding RNA LOC105372125 is significantly associated with susceptibility to schizophrenia and bipolar disorder in Han Chinese women. | Zhao Z et al. | โ | 2022 | โ |
| Genome-wide DNA methylation in an animal model and human studies of schizophrenia: a protocol for a meta-analysis. | Magwai T et al. | โ | 2022 | โ |
| Glutamatergic dysfunction in Schizophrenia. | Kruse AO et al. | โ | 2022 | โ |
| Heritability of specific cognitive functions and associations with schizophrenia spectrum disorders using CANTAB: a nation-wide twin study. | Lemvigh CK et al. | โ | 2022 | โ |
| Heritability: What's the point? What is it not for? A human genetics perspective. | Robette N et al. | โ | 2022 | โ |
| Heritable anisotropy associated with cognitive impairments among patients with schizophrenia and their non-psychotic relatives in multiplex families. | Prasad KM et al. | โ | 2022 | โ |
| How can we obtain truly translational mouse models to improve clinical outcomes in schizophrenia? | Clapcote SJ | โ | 2022 | โ |
| Identifying novel proteins underlying schizophrenia via integrating pQTLs of the plasma, CSF, and brain with GWAS summary data. | Gu X et al. | โ | 2022 | โ |
| Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development. | Liu D et al. | โ | 2022 | โ |
| Influences on the Genetic Relationship Between Cannabis Use and Schizophrenia: The Role of the Externalizing Spectrum. | Wormington B et al. | โ | 2022 | โ |
| <i>NRN1</i> Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches. | Almodรณvar-Payรก C et al. | โ | 2022 | โ |
| Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction. | Guan F et al. | โ | 2022 | โ |
| Investigation of accelerated epigenetic aging in individuals suffering from schizophrenia in the context of lifetime suicide attempt. | Jeremian R et al. | โ | 2022 | โ |
| Investigation of <i>OLIG2</i> as a candidate gene for schizophrenia and autism spectrum disorder. | Furuta S et al. | โ | 2022 | โ |
| Involvement of the long intergenic non-coding RNA LINC00461 in schizophrenia. | Rao S et al. | โ | 2022 | โ |
| L1 Retrotransposons: A Potential Endogenous Regulator for Schizophrenia. | Jahangir M et al. | โ | 2022 | โ |
| Leveraging interindividual variability of regulatory activity for refining genetic regulation of gene expression in schizophrenia. | Alver M et al. | โ | 2022 | โ |
| Mapping miRNA Research in Schizophrenia: A Scientometric Review. | Lim M et al. | โ | 2022 | โ |
| Multi-modal intermediate integrative methods in neuropsychiatric disorders: A review. | Wang Y et al. | โ | 2022 | โ |
| New insights of the role of the KCNH2 gene in schizophrenia: An fMRI case-control study. | Guardiola-Ripoll M et al. | โ | 2022 | โ |
| Novel disease associations with schizophrenia genetic risk revealed in ~400,000 UK Biobank participants. | Zhang R et al. | โ | 2022 | โ |
| Novel IL1RAP mutation associated with schizophrenia interferes with neuronal growth and related NF-ฮบB signal pathways. | Cheng P et al. | โ | 2022 | โ |
| Novel open reading frames in human accelerated regions and transposable elements reveal new leads to understand schizophrenia and bipolar disorder. | Erady C et al. | โ | 2022 | โ |
| Overlap between genetic variants associated with schizophrenia spectrum disorders and intelligence quotient: a systematic review. | Murillo-Garcรญa N et al. | โ | 2022 | โ |
| Perceptions of causal attribution and attitudes to genetic testing among people with schizophrenia and their first-degree relatives. | Cullen MBR et al. | โ | 2022 | โ |
| Pharmacogenetics and Schizophrenia-Can Genomics Improve the Treatment with Second-Generation Antipsychotics? | Pลaza O et al. | โ | 2022 | โ |
| Polygenic Risk for Schizophrenia Has Sex-Specific Effects on Brain Activity during Memory Processing in Healthy Individuals. | Koch E et al. | โ | 2022 | โ |
| Polygenic risk scores for schizophrenia and major depression are associated with socio-economic indicators of adversity in two British community samples. | Machlitt-Northen S et al. | โ | 2022 | โ |
| Polygenic scores for schizophrenia and major depression are associated with psychosocial risk factors in children: evidence of gene-environment correlation. | Machlitt-Northen S et al. | โ | 2022 | โ |
| Quantifying the heritability of belief formation. | Vellani V et al. | โ | 2022 | โ |
| Recent Advances and Future Directions in Brain MR Imaging Studies in Schizophrenia: Toward Elucidating Brain Pathology and Developing Clinical Tools. | Koike S et al. | โ | 2022 | โ |
| Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression. | Li Y et al. | โ | 2022 | โ |
| Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression. | Li S et al. | โ | 2022 | โ |
| Reprint of: Elemental dysregulation in psychotic spectrum disorders: A review and research synthesis. | Zaks N et al. | โ | 2022 | โ |
| Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes. | Pingault JB et al. | โ | 2022 | โ |
| Revisiting tandem repeats in psychiatric disorders from perspectives of genetics, physiology, and brain evolution. | Xiao X et al. | โ | 2022 | โ |
| Roles of neuroligins in central nervous system development: focus on glial neuroligins and neuron neuroligins. | Liu X et al. | โ | 2022 | โ |
| Schizophrenia. | Jauhar S et al. | โ | 2022 | โ |
| Structural and Functional Deviations of the Hippocampus in Schizophrenia and Schizophrenia Animal Models. | Wegrzyn D et al. | โ | 2022 | โ |
| Structural covariance networks in schizophrenia: A systematic review Part II. | Prasad K et al. | โ | 2022 | โ |
| Supplementation of PQQ from pregnancy prevents MK-801-induced schizophrenia-like behaviors in mice. | Peng Y et al. | โ | 2022 | โ |
| The beginnings of biometrical psychiatric genetics: Studies of the insane diathesis 1905-1909. | Kendler KS | โ | 2022 | โ |
| The Beginnings of Scientific Psychiatric Twin Research: Luxenburger's 1928 "Preliminary Report on the Psychiatric Examination of a Series of Twins". | Kendler KS et al. | โ | 2022 | โ |
| The impact of educational attainment, intelligence and intellectual disability on schizophrenia: a Swedish population-based register and genetic study. | Song J et al. | โ | 2022 | โ |
| The Neuropsychiatric Approach to the Assessment of Patients in Neurology. | Trapp NT et al. | โ | 2022 | โ |
| The p21-activated kinases in neural cytoskeletal remodeling and related neurological disorders. | Zhang K et al. | โ | 2022 | โ |
| Third-generation genome sequencing implicates medium-sized structural variants in chronic schizophrenia. | Lee CC et al. | โ | 2022 | โ |
| Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants. | Sanders B et al. | โ | 2022 | โ |
| Working memory deficits in children with schizophrenia and its mechanism, susceptibility genes, and improvement: A literature review. | Zhou J et al. | โ | 2022 | โ |
| 3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders. | Su C et al. | โ | 2021 | โ |
| Advances in Proteomics Allow Insights Into Neuronal Proteomes. | Fingleton E et al. | โ | 2021 | โ |
| A genetic risk score using human chromosomal-scale length variation can predict schizophrenia. | Toh C et al. | โ | 2021 | โ |
| A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MTd2d3 and Mushroom Dendritic Spine Density. | Cai X et al. | โ | 2021 | โ |
| Alteration of lipids and amino acids in plasma distinguish schizophrenia patients from controls: A targeted metabolomics study. | Liu Y et al. | โ | 2021 | โ |
| Alterations in hippocampal subfield volumes among schizophrenia patients, their first-degree relatives and healthy subjects. | Ohi K et al. | โ | 2021 | โ |
| Alternative models for transgenerational epigenetic inheritance: Molecular psychiatry beyond mice and man. | Hime GR et al. | โ | 2021 | โ |
| A machine learning case-control classifier for schizophrenia based on DNA methylation in blood. | Gunasekara CJ et al. | โ | 2021 | โ |
| Analysis of Major Depression Risk Genes Reveals Evolutionary Conservation, Shared Phenotypes, and Extensive Genetic Interactions. | Sall S et al. | โ | 2021 | โ |
| Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations. | Lรคhteenvuo M et al. | โ | 2021 | โ |
| Applying stem cells and CRISPR engineering to uncover the etiology of schizophrenia. | Michael Deans PJ et al. | โ | 2021 | โ |
| A Recessively Inherited Risk Locus on Chromosome 13q22-31 Conferring Susceptibility to Schizophrenia. | Mahmood T et al. | โ | 2021 | โ |
| Association between rs1344706 Polymorphism in the ZNF804A Gene and the Risk for Schizophrenia. | Esmaeili A et al. | โ | 2021 | โ |
| A unique missense variant in the E1A-binding protein P400 gene is implicated in schizophrenia by whole-exome sequencing and mutant mouse models. | Morimoto Y et al. | โ | 2021 | โ |
| Axonal branch patterning and neuronal shape diversity: roles in developmental circuit assembly: Axonal branch patterning and neuronal shape diversity in developmental circuit assembly. | Hoersting AK et al. | โ | 2021 | โ |
| Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia. | Kim M et al. | โ | 2021 | โ |
| Causal associations of intelligence with schizophrenia and bipolar disorder: A Mendelian randomization analysis. | Ohi K et al. | โ | 2021 | โ |
| Characteristics of Multimodal Brain Connectomics in Patients With Schizophrenia and the Unaffected First-Degree Relatives. | Lin X et al. | โ | 2021 | โ |
| Convergent lines of evidence support <i>NOTCH4</i> as a schizophrenia risk gene. | Zhang Y et al. | โ | 2021 | โ |
| Deficit syndrome in Chinese patients with first-episode drug naรฏve schizophrenia: Prevalence, demographic and clinical characteristics. | Liu J et al. | โ | 2021 | โ |
| Detection of Morphological Abnormalities in Schizophrenia: An Important Step to Identify Associated Genetic Disorders or Etiologic Subtypes. | Priol AC et al. | โ | 2021 | โ |
| Disorganization of Oscillatory Activity in Animal Models of Schizophrenia. | Speers LJ et al. | โ | 2021 | โ |
| Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics. | Buch AM et al. | โ | 2021 | โ |
| DNA Methylation and Schizophrenia: Current Literature and Future Perspective. | Magwai T et al. | โ | 2021 | โ |
| DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia. | Hannon E et al. | โ | 2021 | โ |
| EEG Microstates and Psychosocial Stress During an Exchange Year. | Kadier N et al. | โ | 2021 | โ |
| Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank. | Caseras X et al. | โ | 2021 | โ |
| Elemental dysregulation in psychotic spectrum disorders: A review and research synthesis. | Zaks N et al. | โ | 2021 | โ |
| Elevated levels of IL-18 associated with schizophrenia and first episode psychosis: A systematic review and meta-analysis. | Syed AAS et al. | โ | 2021 | โ |
| Environmental Risk Factors for Schizophrenia and Bipolar Disorder and Their Relationship to Genetic Risk: Current Knowledge and Future Directions. | Robinson N et al. | โ | 2021 | โ |
| Estimating Aggregate Environmental Risk Score in Psychiatry: The Exposome Score for Schizophrenia. | Pries LK et al. | โ | 2021 | โ |
| Familial co-aggregation of schizophrenia and eating disorders in Sweden and Denmark. | Zhang R et al. | โ | 2021 | โ |
| Functional Analysis of <i>DNMT1</i> SNPs (<i>rs2228611</i> and <i>rs2114724</i>) Associated with Schizophrenia. | Saxena S et al. | โ | 2021 | โ |
| Functional variants fine-mapping and gene function characterization provide insights into the role of ZNF323 in schizophrenia pathogenesis. | Li S et al. | โ | 2021 | โ |
| FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors. | Shen M et al. | โ | 2021 | โ |
| GABAergic System Dysfunction and Challenges in Schizophrenia Research. | Jahangir M et al. | โ | 2021 | โ |
| Generative network models of altered structural brain connectivity in schizophrenia. | Zhang X et al. | โ | 2021 | โ |
| Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness. | Cheng W et al. | โ | 2021 | โ |
| Genetic contributions to anxiety disorders: where we are and where we are heading. | Ask H et al. | โ | 2021 | โ |
| Genetic underpinnings of schizophrenia-related electroencephalographical intermediate phenotypes: A systematic review and meta-analysis. | Hederih J et al. | โ | 2021 | โ |
| Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium. | Peterson RE et al. | โ | 2021 | โ |
| Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia. | Liu J et al. | โ | 2021 | โ |
| Genome wide association study identifies four loci for early onset schizophrenia. | Guo S et al. | โ | 2021 | โ |
| Genomic perspectives on the circadian clock hypothesis of psychiatric disorders. | von Schantz M et al. | โ | 2021 | โ |
| Global Scientific Outputs of Schizophrenia Publications From 1975 to 2020: a Bibliometric Analysis. | Kiraz S et al. | โ | 2021 | โ |
| Glutathione Levels and Glutathione-Glutamate Correlation in Patients With Treatment-Resistant Schizophrenia. | Iwata Y et al. | โ | 2021 | โ |
| Grey and white matter microstructure is associated with polygenic risk for schizophrenia. | Stauffer EM et al. | โ | 2021 | โ |
| Hidden Role of Gut Microbiome Dysbiosis in Schizophrenia: Antipsychotics or Psychobiotics as Therapeutics? | Munawar N et al. | โ | 2021 | โ |
| High-impact rare genetic variants in severe schizophrenia. | Zoghbi AW et al. | โ | 2021 | โ |
| How do established developmental risk-factors for schizophrenia change the way the brain develops? | Eyles DW | โ | 2021 | โ |
| Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT's Role in Complex Brain Disorders and Neurological Disease. | Levenga J et al. | โ | 2021 | โ |
| Infections, antibiotic treatment and the Microbiome in relation to schizophrenia. | Klein-Petersen AW et al. | โ | 2021 | โ |
| <i>NLRP3</i> Influences Cognitive Function in Schizophrenia in Han Chinese. | Liu R et al. | โ | 2021 | โ |
| Integrative Analyses Followed by Functional Characterization Reveal TMEM180 as a Schizophrenia Risk Gene. | Wang JY et al. | โ | 2021 | โ |
| KALRN: A central regulator of synaptic function and synaptopathies. | Parnell E et al. | โ | 2021 | โ |
| Low-Level Brain Somatic Mutations Are Implicated in Schizophrenia. | Kim MH et al. | โ | 2021 | โ |
| Lumateperone tosylate, A Selective and Concurrent Modulator of Serotonin, Dopamine, and Glutamate, in the Treatment of Schizophrenia. | Maini K et al. | โ | 2021 | โ |
| MAD1L1 and TSNARE gene polymorphisms are associated with schizophrenia susceptibility in the Han Chinese population. | Liu X et al. | โ | 2021 | โ |
| Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. | Nabais MF et al. | โ | 2021 | โ |
| MicroRNAs in the Onset of Schizophrenia. | Thomas KT et al. | โ | 2021 | โ |
| Neanderthal-derived genetic variation in living humans relates to schizophrenia diagnosis, to psychotic symptom severity, and to dopamine synthesis. | Gregory MD et al. | โ | 2021 | โ |
| Network modules linking expression and methylation in prefrontal cortex of schizophrenia. | Lin D et al. | โ | 2021 | โ |
| Neurexins in autism and schizophrenia-a review of patient mutations, mouse models and potential future directions. | Tromp A et al. | โ | 2021 | โ |
| [Neurodevelopmental Disorders, Psychiatric Comorbidities and Associated Pathologies in Patients with Childhood-Onset Schizophrenia and Premorbid Autistic Symptoms.] | Fernandez A et al. | โ | 2021 | โ |
| Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome. | Hwang H et al. | โ | 2021 | โ |
| No causal associations between childhood family income and subsequent psychiatric disorders, substance misuse and violent crime arrests: a nationwide Finnish study of >650ย 000 individuals and their siblings. | Sariaslan A et al. | โ | 2021 | โ |
| Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia. | Lencz T et al. | โ | 2021 | โ |
| Oxidative stress and schizophrenia: A comparative cross-sectional study of multiple oxidative markers in patients and their first-degree relatives. | Guler EM et al. | โ | 2021 | โ |
| Paliperidone Reversion of Maternal Immune Activation-Induced Changes on Brain Serotonin and Kynurenine Pathways. | MacDowell KS et al. | โ | 2021 | โ |
| Polygenic Risk Scores Differentiating Schizophrenia From Bipolar Disorder Are Associated With Premorbid Intelligence in Schizophrenia Patients and Healthy Subjects. | Ohi K et al. | โ | 2021 | โ |
| Postnatal therapeutic approaches in genetic neurodevelopmental disorders. | Levy G et al. | โ | 2021 | โ |
| Psychotic-Like Experiences in Adolescence Occurring in Combination or Isolation: Associations with Schizophrenia Risk Factors. | Cardno AG et al. | โ | 2021 | โ |
| Rare germline variants in individuals diagnosed with schizophrenia within multiplex families. | Li S et al. | โ | 2021 | โ |
| Safety and related factors of treatment with long-term atypical antipsychotic in Chinese patients with schizophrenia: observational study. | Yu W et al. | โ | 2021 | โ |
| Schizophrenia-associated variation at ZNF804A correlates with altered experience-dependent dynamics of sleep slow waves and spindles in healthy young adults. | Bartsch U et al. | โ | 2021 | โ |
| Schizophrenia: Complement Cleaning or Killing. | Hogenaar JTT et al. | โ | 2021 | โ |
| Sex specific effect of gut microbiota on the risk of psychiatric disorders: A Mendelian randomisation study and PRS analysis using UK Biobank cohort. | Qi X et al. | โ | 2021 | โ |
| Sex-specific effects of polygenic risk for schizophrenia on lifespan cognitive functioning in healthy individuals. | Koch E et al. | โ | 2021 | โ |
| Targeted sequencing and integrative analysis to prioritize candidate genes in neurodevelopmental disorders. | Zhang Y et al. | โ | 2021 | โ |
| The clinical, imaging and biological features of psychosis in Han Chinese patients with Huntington's disease. | Li XY et al. | โ | 2021 | โ |
| The Stop Signal Task for Measuring Behavioral Inhibition in Mice With Increased Sensitivity and High-Throughput Operation. | Caglayan A et al. | โ | 2021 | โ |
| Transcriptome-Wide Association Study Provides Insights Into the Genetic Component of Gene Expression in Anxiety. | Su X et al. | โ | 2021 | โ |
| Using iPSC Models to Understand the Role of Estrogen in Neuron-Glia Interactions in Schizophrenia and Bipolar Disorder. | Reis de Assis D et al. | โ | 2021 | โ |
| Utility of polygenic embryo screening for disease depends on the selection strategy. | Lencz T et al. | โ | 2021 | โ |
| Weak Association Between the Glutamate Decarboxylase 1 Gene (GAD1) and Schizophrenia in Han Chinese Population. | Zhang L et al. | โ | 2021 | โ |
| Working memory deficits in schizophrenia are associated with the rs34884856 variant and expression levels of the NR4A2 gene in a sample Mexican population: a case control study. | Ruiz-Sรกnchez E et al. | โ | 2021 | โ |
| Adolescent cannabinoid exposure interacts with other risk factors in schizophrenia: A review of the evidence from animal models. | Dunn AL et al. | โ | 2020 | โ |
| Adverse childhood experiences lead to trans-generational transmission of early maladaptive schemas. | Zeynel Z et al. | โ | 2020 | โ |
| Alteration of the gut microbiome in first-episode drug-naรฏve and chronic medicated schizophrenia correlate with regional brain volumes. | Ma X et al. | โ | 2020 | โ |
| Analysis of KCNH2 and CACNA1C schizophrenia risk genes on EEG functional network modulation during an auditory odd-ball task. | Lubeiro A et al. | โ | 2020 | โ |
| ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk. | Sekiguchi M et al. | โ | 2020 | โ |
| Assessment Causality in Associations Between Serum Uric Acid and Risk of Schizophrenia: A Two-Sample Bidirectional Mendelian Randomization Study. | Luo Q et al. | โ | 2020 | โ |
| Association between a <i>TCF4</i> Polymorphism and Susceptibility to Schizophrenia. | Gao JY et al. | โ | 2020 | โ |
| Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia. | Engemann K et al. | โ | 2020 | โ |
| Association between DRD2 and ANKK1 polymorphisms with the deficit syndrome in schizophrenia. | Michalczyk A et al. | โ | 2020 | โ |
| Association between functional and structural connectivity of the corticostriatal network in people with schizophrenia and unaffected first-degree relatives. | Li P et al. | โ | 2020 | โ |
| Association Between Glutathione S-Transferase (GST) Polymorphisms and Schizophrenia in a Chinese Han Population. | Yan C et al. | โ | 2020 | โ |
| Association between <i>EFHD2</i> gene polymorphisms and schizophrenia among the Han population in northern China. | Gao M et al. | โ | 2020 | โ |
| Association between polygenic liability for schizophrenia and substance involvement: A nationwide population-based study in Taiwan. | Wang SH et al. | โ | 2020 | โ |
| Association between Serum Essential Metal Elements and the Risk of Schizophrenia in China. | Ma J et al. | โ | 2020 | โ |
| Association of ADH7 Gene Polymorphism with Schizophrenia in the Han Population of Northern China: a Case-Control Study. | Zeng K et al. | โ | 2020 | โ |
| Association of a Reproducible Epigenetic Risk Profile for Schizophrenia With Brain Methylation and Function. | Chen J et al. | โ | 2020 | โ |
| Associations between schizophrenia polygenic risk and apathy in schizophrenia spectrum disorders and healthy controls. | Lyngstad SH et al. | โ | 2020 | โ |
| BDNF Serum Levels are Associated With White Matter Microstructure in Schizophrenia - A Pilot Study. | Hammans C et al. | โ | 2020 | โ |
| Beneficial effects of omega-3 fatty acid supplementation in schizophrenia: possible mechanisms. | Hsu MC et al. | โ | 2020 | โ |
| Blood plasma proteomic modulation induced by olanzapine and risperidone in schizophrenia patients. | Garcia-Rosa S et al. | โ | 2020 | โ |
| Brain structural correlates of familial risk for mental illness: a meta-analysis of voxel-based morphometry studies in relatives of patients with psychotic or mood disorders. | Zhang W et al. | โ | 2020 | โ |
| Catechol-O-methyltransferase gene expression in stress-induced and non-stress induced schizophrenia. | Aghamaleki-Sarvestani Z et al. | โ | 2020 | โ |
| Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry. | Bigdeli TB et al. | โ | 2020 | โ |
| CRISPR-based functional evaluation of schizophrenia risk variants. | Rajarajan P et al. | โ | 2020 | โ |
| Dendritic Spine Plasticity: Function and Mechanisms. | Runge K et al. | โ | 2020 | โ |
| Differences in executive function among patients with schizophrenia, their unaffected first-degree relatives and healthy participants. | Kataoka Y et al. | โ | 2020 | โ |
| Dissecting the molecular biology of schizophrenia: A call for emphasising genetic and phenotypic heterogeneity: commentary on Torrey and Yolken (this issue). | Schwab SG | โ | 2020 | โ |
| Effect of ZNF804A gene polymorphism (rs1344706) on the plasticity of the functional coupling between the right dorsolateral prefrontal cortex and the contralateral hippocampal formation. | Zhao W et al. | โ | 2020 | โ |
| Effects of HTR1B 3' region polymorphisms and functional regions on gene expression regulation. | Xia X et al. | โ | 2020 | โ |
| Effort-related decision making in humanized COMT mice: Effects of Val<sup>158</sup>Met polymorphisms and possible implications for negative symptoms in humans. | Yang JH et al. | โ | 2020 | โ |
| Epidemiological Studies of Prenatal and Childhood Infection and Schizophrenia. | Karlsson H et al. | โ | 2020 | โ |
| Examining which factors influence age of onset in males and females with schizophrenia. | Neill E et al. | โ | 2020 | โ |
| Expression of Behavioral Phenotypes in Genetic and Environmental Mouse Models of Schizophrenia. | Sultana R et al. | โ | 2020 | โ |
| Extending schizophrenia diagnostic model to predict schizotypy in first-degree relatives. | Kalmady SV et al. | โ | 2020 | โ |
| Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia. | Evgrafov OV et al. | โ | 2020 | โ |
| Gene-set Enrichment with Mathematical Biology (GEMB). | Cochran AL et al. | โ | 2020 | โ |
| Genetic polymorphisms of PIP5K2A and course of schizophrenia. | Poltavskaya EG et al. | โ | 2020 | โ |
| Genetics and major depressive disorder: clinical implications for disease risk, prognosis and treatment. | Fabbri C et al. | โ | 2020 | โ |
| Genetics of schizophrenia (Review). | Trifu SC et al. | โ | 2020 | โ |
| Genome-Wide Search for SNP Interactions in GWAS Data: Algorithm, Feasibility, Replication Using Schizophrenia Datasets. | Lee KY et al. | โ | 2020 | โ |
| Genomic Chaos Begets Psychiatric Disorder. | Dwyer DS | โ | 2020 | โ |
| Glutamate in schizophrenia: Neurodevelopmental perspectives and drug development. | Egerton A et al. | โ | 2020 | โ |
| Human Pluripotent Stem Cells: Applications and Challenges for Regenerative Medicine and Disease Modeling. | Miranda CC et al. | โ | 2020 | โ |
| Identification of 34 genes conferring genetic and pharmacological risk for the comorbidity of schizophrenia and smoking behaviors. | Ma Y et al. | โ | 2020 | โ |
| Identification of a functional 339 bp <i>Alu</i> insertion polymorphism in the schizophrenia-associated locus at 10q24.32. | Yang ZH et al. | โ | 2020 | โ |
| Identification of a functional SNP rs7304782 at schizophrenia risk locus 12q24.31 and validation of its association with schiz ophrenia in Chinese populations. | Ma C et al. | โ | 2020 | โ |
| Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia. | Halvorsen M et al. | โ | 2020 | โ |
| Integrative In Silico Analysis of Genome-Wide DNA Methylation Profiles in Schizophrenia. | Forero DA et al. | โ | 2020 | โ |
| Interactome overlap between schizophrenia and cognition. | Koch E et al. | โ | 2020 | โ |
| In Vitro and In Vivo Models for the Investigation of Potential Drugs Against Schizophrenia. | Koszลa O et al. | โ | 2020 | โ |
| Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders. | Wong H et al. | โ | 2020 | โ |
| KCNH2-3.1 mediates aberrant complement activation and impaired hippocampal-medial prefrontal circuitry associated with working memory deficits. | Ren M et al. | โ | 2020 | โ |
| Loss-of-function Mutations of CUL3, a High Confidence Gene for Psychiatric Disorders, Lead to Aberrant Neurodevelopment In Human Induced Pluripotent Stem Cells. | Fischer S et al. | โ | 2020 | โ |
| Machine learning analysis of exome trios to contrast the genomic architecture of autism and schizophrenia. | Sardaar S et al. | โ | 2020 | โ |
| Maternal Bacterial Infection During Pregnancy and Offspring Risk of Psychotic Disorders: Variation by Severity of Infection and Offspring Sex. | Lee YH et al. | โ | 2020 | โ |
| Mental health dished up-the use of iPSC models in neuropsychiatric research. | McNeill RV et al. | โ | 2020 | โ |
| Mental health is biological health: Why tackling "diseases of the mind" is an imperative for biological anthropology in the 21st century. | Syme KL et al. | โ | 2020 | โ |
| Meta-analysis of cytokine and C-reactive protein levels in high-risk psychosis. | Park S et al. | โ | 2020 | โ |
| Meta-analysis of total and differential white blood cell counts in schizophrenia. | Jackson AJ et al. | โ | 2020 | โ |
| mHealth for schizophrenia spectrum disorders management: A systematic review. | Chivilgina O et al. | โ | 2020 | โ |
| Neurocognitive and neurophysiological endophenotypes in schizophrenia: An overview. | Donati FL et al. | โ | 2020 | โ |
| Neuronal Differentiation of Induced Pluripotent Stem Cells from Schizophrenia Patients in Two-Dimensional and in Three-Dimensional Cultures Reveals Increased Expression of the Kv4.2 Subunit DPP6 That Contributes to Decreased Neuronal Activity. | Naujock M et al. | โ | 2020 | โ |
| No association between the Ser9Gly polymorphism of the dopamine receptor D3 gene and schizophrenia: a meta-analysis of family-based association studies. | Li XN et al. | โ | 2020 | โ |
| No Evidence for Widespread Positive Selection Signatures in Common Risk Alleles Associated with Schizophrenia. | Yao Y et al. | โ | 2020 | โ |
| Novel Approaches for Identifying the Molecular Background of Schizophrenia. | Golov AK et al. | โ | 2020 | โ |
| Overexpression of complement component C4 in the dorsolateral prefrontal cortex, parietal cortex, superior temporal gyrus and associative striatum of patients with schizophrenia. | Rey R et al. | โ | 2020 | โ |
| Overview of schizophrenia research and treatment in Pakistan. | Nawaz R et al. | โ | 2020 | โ |
| Pharmacological enrichment of polygenic risk for precision medicine in complex disorders. | Reay WR et al. | โ | 2020 | โ |
| Polygenetic Risk Scores for Major Psychiatric Disorders Among Schizophrenia Patients, Their First-Degree Relatives, and Healthy Participants. | Ohi K et al. | โ | 2020 | โ |
| Polygenic analysis suggests the involvement of calcium signaling in executive function in schizophrenia patients. | Kirchner SK et al. | โ | 2020 | โ |
| Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort. | Grama S et al. | โ | 2020 | โ |
| Polygenic risk scores for late smoking initiation associated with the risk of schizophrenia. | Ohi K et al. | โ | 2020 | โ |
| Polygenic Risk Scores for Subtyping of Schizophrenia. | Chen J et al. | โ | 2020 | โ |
| Polygenic risk scores: from research tools to clinical instruments. | Lewis CM et al. | โ | 2020 | โ |
| Polygenic risk scores in schizophrenia with clinically significant copy number variants. | Taniguchi S et al. | โ | 2020 | โ |
| Polygenic Risk Scores Shed Light on the Relationship between Schizophrenia and Cognitive Functioning: Review and Meta-Analysis. | Mallet J et al. | โ | 2020 | โ |
| Postzygotic Somatic Mutations in the Human Brain Expand the Threshold-Liability Model of Schizophrenia. | Singh SM et al. | โ | 2020 | โ |
| Predicting response to electroconvulsive therapy combined with antipsychotics in schizophrenia using multi-parametric magnetic resonance imaging. | Gong J et al. | โ | 2020 | โ |
| Psychiatric Polygenic Risk Scores as Predictor for Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in a Clinical Child and Adolescent Sample. | Jansen AG et al. | โ | 2020 | โ |
| Psychosis in Alzheimer's Disease. | Ballard C et al. | โ | 2020 | โ |
| Pyrosequencing analysis of IRS1 methylation levels in schizophrenia with tardive dyskinesia. | Li Y et al. | โ | 2020 | โ |
| Rare single-nucleotide DAB1 variants and their contribution to Schizophrenia and autism spectrum disorder susceptibility. | Nawa Y et al. | โ | 2020 | โ |
| Rare variants and biological pathways identified in treatment-refractory depression. | McClain LL et al. | โ | 2020 | โ |
| Recent advances with 5-HT<sub>3</sub> modulators for neuropsychiatric and gastrointestinal disorders. | Juza R et al. | โ | 2020 | โ |
| Reduced connectivity in anterior cingulate cortex as an early predictor for treatment response in drug-naive, first-episode schizophrenia: A global-brain functional connectivity analysis. | Li H et al. | โ | 2020 | โ |
| Risk factors of hyperprolactinemia induced by risperidone and olanzapine and their correlations with plasma glucose and lipids. | He S et al. | โ | 2020 | โ |
| Schizophrenia-An Overview. | McCutcheon RA et al. | โ | 2020 | โ |
| Schizophrenia in a genomic era: a review from the pathogenesis, genetic and environmental etiology to diagnosis and treatment insights. | Zamanpoor M | โ | 2020 | โ |
| Schizophrenia patients and their healthy siblings share decreased prefronto-thalamic connectivity but not increased sensorimotor-thalamic connectivity. | Xi C et al. | โ | 2020 | โ |
| Short-active photoperiod gestation induces psychiatry-relevant behavior in healthy mice but a resiliency to such effects are seen in mice with reduced dopamine transporter expression. | Kwiatkowski MA et al. | โ | 2020 | โ |
| Stem Cells for Improving the Treatment of Neurodevelopmental Disorders. | Donegan JJ et al. | โ | 2020 | โ |
| Structural and functional alterations in the brain gray matter among first-degree relatives of schizophrenia patients: A multimodal meta-analysis of fMRI and VBM studies. | Saarinen AIL et al. | โ | 2020 | โ |
| The application of human pluripotent stem cells to model the neuronal and glial components of neurodevelopmental disorders. | Lee KM et al. | โ | 2020 | โ |
| The connection between microbiome and schizophrenia. | Golofast B et al. | โ | 2020 | โ |
| The Gut Microbiome and Schizophrenia: The Current State of the Field and Clinical Applications. | Szeligowski T et al. | โ | 2020 | โ |
| The interaction of histone modification related H3F3B and NSD2 genes increases the susceptibility to schizophrenia in a Chinese population. | Liu W et al. | โ | 2020 | โ |
| The Maudsley environmental risk score for psychosis. | Vassos E et al. | โ | 2020 | โ |
| The polygenic architecture of schizophrenia - rethinking pathogenesis and nosology. | Smeland OB et al. | โ | 2020 | โ |
| The relationship of genetic susceptibilities for psychosis with physiological fluctuation in functional MRI data. | Saarinen A et al. | โ | 2020 | โ |
| The Role of Aberrations in the Immune-Inflammatory Response System (IRS) and the Compensatory Immune-Regulatory Reflex System (CIRS) in Different Phenotypes of Schizophrenia: the IRS-CIRS Theory of Schizophrenia. | Roomruangwong C et al. | โ | 2020 | โ |
| The role of altered brain structural connectivity in resilience, vulnerability, and disease expression to schizophrenia. | Wei Q et al. | โ | 2020 | โ |
| The role of norepinephrine in the pathophysiology of schizophrenia. | Mรคki-Marttunen V et al. | โ | 2020 | โ |
| The Role of Zebrafish and Laboratory Rodents in Schizophrenia Research. | Langova V et al. | โ | 2020 | โ |
| Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk. | Anderson KM et al. | โ | 2020 | โ |
| Transcriptome analysis of fibroblasts from schizophrenia patients reveals differential expression of schizophrenia-related genes. | Etemadikhah M et al. | โ | 2020 | โ |
| Understanding the genetics of neuropsychiatric disorders: the potential role of genomic regulatory blocks. | Bareลกiฤ A et al. | โ | 2020 | โ |
| Wnt receptor gene <i>FZD1</i> was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort. | Liu X et al. | โ | 2020 | โ |
| Zebrafish as a tool to study schizophrenia-associated copy number variants. | Campbell PD et al. | โ | 2020 | โ |
| A Case-Control Study of ABCB1, ABCB6, and ABCG1 Polymorphisms and Schizophrenia in a Han Chinese Population. | Ma G et al. | โ | 2019 | โ |
| A Cross-Species Systems Genetics Analysis Links APBB1IP as a Candidate for Schizophrenia and Prepulse Inhibition. | Ashbrook DG et al. | โ | 2019 | โ |
| Adolescent stress contributes to aberrant dopamine signaling in a heritable rodent model of susceptibility. | Perez SM et al. | โ | 2019 | โ |
| A framework for linking resting-state chronnectome/genome features in schizophrenia: A pilot study. | Rashid B et al. | โ | 2019 | โ |
| Altered Expression of a Unique Set of Genes Reveals Complex Etiology of Schizophrenia. | Kumar A et al. | โ | 2019 | โ |
| Altered expression of the CSMD1 gene in the peripheral blood of schizophrenia patients. | Liu Y et al. | โ | 2019 | โ |
| A method for building a genome-connectome bipartite graph model. | Yu Q et al. | โ | 2019 | โ |
| Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia. | Banerjee N et al. | โ | 2019 | โ |
| Assessing whether the association between rheumatoid arthritis and schizophrenia is bidirectional: A nationwide population-based cohort study. | Chen SF et al. | โ | 2019 | โ |
| Association between NRGN gene polymorphism and resting-state hippocampal functional connectivity in schizophrenia. | Zhang Y et al. | โ | 2019 | โ |
| Association between RELN polymorphisms and schizophrenia in a Han population from Northeast China. | Bai W et al. | โ | 2019 | โ |
| Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study. | Periyasamy S et al. | โ | 2019 | โ |
| Association study of the excitatory amino acid transporter 2 (EAAT2) and glycine transporter 1 (GlyT1) gene polymorphism with schizophrenia in a Polish population. | Merk W et al. | โ | 2019 | โ |
| A systematic review of factors that influence the efficacy of cognitive remediation therapy in schizophrenia. | Reser MP et al. | โ | 2019 | โ |
| Biological and practical implications of genome-wide association study of schizophrenia using Bayesian variable selection. | Rowe B et al. | โ | 2019 | โ |
| Brain Banks Spur New Frontiers in Neuropsychiatric Research and Strategies for Analysis and Validation. | Wang L et al. | โ | 2019 | โ |
| Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk. | Alnรฆs D et al. | โ | 2019 | โ |
| CACNA1C (rs1006737) may be a susceptibility gene for schizophrenia: An updated meta-analysis. | Zhu D et al. | โ | 2019 | โ |
| Case Report of Childhood-Onset Psychosis in a Patient with a Known WNT10A Mutation. | Kobza AO et al. | โ | 2019 | โ |
| Childhood Trauma in Schizophrenia: Current Findings and Research Perspectives. | Popovic D et al. | โ | 2019 | โ |
| Common genetic variants have associations with human cortical brain regions and risk of schizophrenia. | Bi X et al. | โ | 2019 | โ |
| Comprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia. | Niu HM et al. | โ | 2019 | โ |
| Contribution of induced pluripotent stem cell technologies to the understanding of cellular phenotypes in schizophrenia. | Balan S et al. | โ | 2019 | โ |
| Developing zebrafish experimental animal models relevant to schizophrenia. | Demin KA et al. | โ | 2019 | โ |
| Double-Edged Sword of Tumour Suppressor Genes in Schizophrenia. | Zhuo C et al. | โ | 2019 | โ |
| Dynamic expression of genes associated with schizophrenia and bipolar disorder across development. | Clifton NE et al. | โ | 2019 | โ |
| Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. | Shao Z et al. | โ | 2019 | โ |
| Dysregulation of a specific immune-related network of genes biologically defines a subset of schizophrenia. | Trossbach SV et al. | โ | 2019 | โ |
| Endophenotypes in Schizophrenia: Digging Deeper to Identify Genetic Mechanisms. | Greenwood TA et al. | โ | 2019 | โ |
| Epigenetics and Common Non Communicable Disease. | Tabatabaiefar MA et al. | โ | 2019 | โ |
| Epigenetics and depressionโฉ. | Penner-Goeke S et al. | โ | 2019 | โ |
| Evidence for cerebello-thalamo-cortical hyperconnectivity as a heritable trait for schizophrenia. | Cao H et al. | โ | 2019 | โ |
| Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease. | Creese B et al. | โ | 2019 | โ |
| Exome sequencing in families with severe mental illness identifies novel and rare variants in genes implicated in Mendelian neuropsychiatric syndromes. | Ganesh S et al. | โ | 2019 | โ |
| Familial abnormalities of endocannabinoid signaling in schizophrenia. | Koethe D et al. | โ | 2019 | โ |
| Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. | Hu TM et al. | โ | 2019 | โ |
| Functional analysis of haplotypes and promoter activity at the 5' region of the human GABRB3 gene and associations with schizophrenia. | Liu Y et al. | โ | 2019 | โ |
| Functional genomics reveal gene regulatory mechanisms underlying schizophrenia risk. | Huo Y et al. | โ | 2019 | โ |
| Genome-Wide Variants Shared Between Smoking Quantity and Schizophrenia on 15q25 Are Associated With CHRNA5 Expression in the Brain. | Ohi K et al. | โ | 2019 | โ |
| Glutamatergic Neurometabolite Levels in Patients With Ultra-Treatment-Resistant Schizophrenia: A Cross-Sectional 3T Proton Magnetic Resonance Spectroscopy Study. | Iwata Y et al. | โ | 2019 | โ |
| GWAS of Behavioral Traits. | Mehta D et al. | โ | 2019 | โ |
| Hair cortisol concentrations as an indicator of potential HPA axis hyperactivation in risk for psychosis. | Sรถder E et al. | โ | 2019 | โ |
| Imaging Genetics Towards a Refined Diagnosis of Schizophrenia. | Jiang W et al. | โ | 2019 | โ |
| Impaired insulin signaling in unaffected siblings and patients with first-episode psychosis. | Chouinard VA et al. | โ | 2019 | โ |
| Intellectual and cognitive profiles in patients affected by schizophrenia. | Bechi M et al. | โ | 2019 | โ |
| Interaction of schizophrenia polygenic risk and cortisol level on pre-adolescent brain structure. | Bolhuis K et al. | โ | 2019 | โ |
| Joint Contributions of Rare Copy Number Variants and Common SNPs to Risk for Schizophrenia. | Bergen SE et al. | โ | 2019 | โ |
| Machine learning in schizophrenia genomics, a case-control study using 5,090 exomes. | Trakadis YJ et al. | โ | 2019 | โ |
| Mega-analysis of Odds Ratio: A Convergent Method for a Deep Understanding of the Genetic Evidence in Schizophrenia. | Jia P et al. | โ | 2019 | โ |
| Meta-analysis of physical activity and effects of social function and quality of life on the physical activity in patients with schizophrenia. | Ohi K et al. | โ | 2019 | โ |
| Mitochondria, Metabolism, and Redox Mechanisms in Psychiatric Disorders. | Kim Y et al. | โ | 2019 | โ |
| Modeling Psychiatric Diseases with Induced Pluripotent Stem Cells. | van Hugte E et al. | โ | 2019 | โ |
| Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability. | Reynolds RH et al. | โ | 2019 | โ |
| Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patients. | Ma L et al. | โ | 2019 | โ |
| No association between polymorphisms in the promoter region of dopamine receptor D2 gene and schizophrenia in the northern Chinese Han population: A case-control study. | Zhang XC et al. | โ | 2019 | โ |
| No interaction between polygenic scores and childhood trauma in predicting suicide attempt in schizophrenia. | Bani-Fatemi A et al. | โ | 2019 | โ |
| Obsessive-compulsive disorder comorbid with schizophrenia and bipolar disorder. | Sharma LP et al. | โ | 2019 | โ |
| Oscillations in cortico-basal ganglia circuits: implications for Parkinson's disease and other neurologic and psychiatric conditions. | Halje P et al. | โ | 2019 | โ |
| Personality and the Expression of Symptomatology in Schizophrenia and Bipolar Disorder. | Uroลกeviฤ S et al. | โ | 2019 | โ |
| Plasma neuropeptides as circulating biomarkers of multifactorial schizophrenia. | Ni P et al. | โ | 2019 | โ |
| Polygenic liability for schizophrenia predicts shifting-specific executive function deficits and tobacco use in a moderate drinking community sample. | Miller AP et al. | โ | 2019 | โ |
| Polygenic risk for psychiatric disorders correlates with executive function in typical development. | Schork AJ et al. | โ | 2019 | โ |
| Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort. | Escott-Price V et al. | โ | 2019 | โ |
| Polygenic risk score increases schizophrenia liability through cognition-relevant pathways. | Toulopoulou T et al. | โ | 2019 | โ |
| Prediction of Onset of Substance-Induced Psychotic Disorder and Its Progression to Schizophrenia in a Swedish National Sample. | Kendler KS et al. | โ | 2019 | โ |
| Prefrontal Coexpression of Schizophrenia Risk Genes Is Associated With Treatment Response in Patients. | Pergola G et al. | โ | 2019 | โ |
| Preventing discrimination based on psychiatric risk biomarkers. | Brannan C et al. | โ | 2019 | โ |
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| Shared psychotic disorder in children and young people: a systematic review. | Vigo L et al. | โ | 2019 | โ |
| Smoking Rates and Number of Cigarettes Smoked per Day in Schizophrenia: A Large Cohort Meta-Analysis in a Japanese Population. | Ohi K et al. | โ | 2019 | โ |
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| Transcriptional changes in the stress pathway are related to symptoms in schizophrenia and to mood in schizoaffective disorder. | Lee CH et al. | โ | 2019 | โ |
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| Updates in Clinical and Genetics Aspects of Hypermobile Ehlers Danlos Syndrome | Forghani I | โ | 2019 | โ |
| Use of the epigenetic toolboxโจto contextualize common variants associated with schizophrenia riskโฉ. | Rajarajan P et al. | โ | 2019 | โ |
| Zebrafish as an Emerging Model for Bioassay-Guided Natural Product Drug Discovery for Neurological Disorders. | Pitchai A et al. | โ | 2019 | โ |
| A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia. | Gonรงalves VF et al. | โ | 2018 | โ |
| A Family Study of the <i>DSM-5</i> Section III Personality Pathology Model Using the Personality Inventory for the <i>DSM-5</i> (PID-5). | Katz AC et al. | โ | 2018 | โ |
| A genome-wide association study of early gamma-band response in a schizophrenia case-control sample. | Konte B et al. | โ | 2018 | โ |
| Alteration of gray matter microstructure in schizophrenia. | Seitz J et al. | โ | 2018 | โ |
| Analysis of Gene Expression Variance in Schizophrenia Using Structural Equation Modeling. | Igolkina AA et al. | โ | 2018 | โ |
| Analyzing the genes related to nicotine addiction or schizophrenia via a pathway and network based approach. | Hu Y et al. | โ | 2018 | โ |
| A novel homozygous mutation in GAD1 gene described in a schizophrenic patient impairs activity and dimerization of GAD67 enzyme. | Magri C et al. | โ | 2018 | โ |
| A Perspective of the Cross-Tissue Interplay of Genetics, Epigenetics, and Transcriptomics, and Their Relation to Brain Based Phenotypes in Schizophrenia. | Liu J et al. | โ | 2018 | โ |
| A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains. | Ranlund S et al. | โ | 2018 | โ |
| Are Schemas Passed on? A Study on the Association Between Early Maladaptive Schemas in Parents and Their Offspring and the Putative Translating Mechanisms. | Sundag J et al. | โ | 2018 | โ |
| Assessment of Cognition and Personality as Potential Endophenotypes in the Western Australian Family Study of Schizophrenia. | McCarthy NS et al. | โ | 2018 | โ |
| Association between CMYA5 gene polymorphisms and risk of schizophrenia in Uygur population and a meta-analysis. | Han S et al. | โ | 2018 | โ |
| Association of copy number variation across the genome with neuropsychiatric traits in the general population. | Guyatt AL et al. | โ | 2018 | โ |
| Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains. | Blakey R et al. | โ | 2018 | โ |
| A systematic review of genome-wide research on psychotic experiences and negative symptom traits: new revelations and implications for psychiatry. | Ronald A et al. | โ | 2018 | โ |
| Autoimmune diseases are associated with an increased risk of schizophrenia: A nationwide population-based cohort study. | Wang LY et al. | โ | 2018 | โ |
| Changed frontal pole gene expression suggest altered interplay between neurotransmitter, developmental, and inflammatory pathways in schizophrenia. | Scarr E et al. | โ | 2018 | โ |
| Childhood-Onset Schizophrenia: Insights from Induced Pluripotent Stem Cells. | Hoffmann A et al. | โ | 2018 | โ |
| Co-aggregation of major psychiatric disorders in individuals with first-degree relatives with schizophrenia: a nationwide population-based study. | Cheng CM et al. | โ | 2018 | โ |
| Complement Gene Expression Correlates with Superior Frontal Cortical Thickness in Humans. | Allswede DM et al. | โ | 2018 | โ |
| Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes. | Yang CP et al. | โ | 2018 | โ |
| Copy Number Variant in the Region of Adenosine Kinase (ADK) and Its Possible Contribution to Schizophrenia Susceptibility. | Kimura H et al. | โ | 2018 | โ |
| Cross-Tissue Exploration of Genetic and Epigenetic Effects on Brain Gray Matter in Schizophrenia. | Lin D et al. | โ | 2018 | โ |
| Dimensional Traits of Schizotypy Associated With Glycine Receptor GLRA1 Polymorphism: An Exploratory Candidate-Gene Association Study. | Vora AK et al. | โ | 2018 | โ |
| Discovery biology of neuropsychiatric syndromes (DBNS): a center for integrating clinical medicine and basic science. | Viswanath B et al. | โ | 2018 | โ |
| Effect of rs1344706 in the <i>ZNF804A</i> gene on the brain network. | Chen X et al. | โ | 2018 | โ |
| Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. | Bryois J et al. | โ | 2018 | โ |
| Exome Sequencing Identifies <i>TENM4</i> as a Novel Candidate Gene for Schizophrenia in the SCZD2 Locus at 11q14-21. | Xue CB et al. | โ | 2018 | โ |
| Exploration and characterisation of the phenotypic and genetic profiles of patients with early onset schizophrenia associated with autism spectrum disorder and their first-degree relatives: a French multicentre case series study protocol (GenAuDiss). | Fernandez A et al. | โ | 2018 | โ |
| Expression-based drug screening of neural progenitor cells from individuals with schizophrenia. | Readhead B et al. | โ | 2018 | โ |
| Functional analysis of schizophrenia genes using GeneAnalytics program and integrated databases. | Sundararajan T et al. | โ | 2018 | โ |
| Further evidence for the genetic association between <i>CACNA1I</i> and schizophrenia. | Xie Y et al. | โ | 2018 | โ |
| GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation. | Jiang DY et al. | โ | 2018 | โ |
| Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron-astrocyte-microglia dysregulation. | Yeung RK et al. | โ | 2018 | โ |
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| Gene-environment interplay in the etiology of psychosis. | Zwicker A et al. | โ | 2018 | โ |
| Genetic association and meta-analysis of a schizophrenia GWAS variant rs10489202 in East Asian populations. | Yang Y et al. | โ | 2018 | โ |
| Genetic Association of the Norepinephrine Transporter Gene G1287A Polymorphism with Risk of Schizophrenia: A Case-Control Study and Meta-Analysis. | Zhao X et al. | โ | 2018 | โ |
| Genetic Overlap between General Cognitive Function and Schizophrenia: A Review of Cognitive GWASs. | Ohi K et al. | โ | 2018 | โ |
| Genetic risk scores and family history as predictors of schizophrenia in Nordic registers. | Lu Y et al. | โ | 2018 | โ |
| Genetic variability in scaffolding proteins and risk for schizophrenia and autism-spectrum disorders: a systematic review. | Soler J et al. | โ | 2018 | โ |
| Genetic Variants Within Molecular Targets of Antipsychotic Treatment: Effects on Treatment Response, Schizophrenia Risk, and Psychopathological Features. | Calabrรฒ M et al. | โ | 2018 | โ |
| Genetic vulnerability to schizophrenia is associated with cannabis use patterns during adolescence. | Hiemstra M et al. | โ | 2018 | โ |
| Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia. | Bansal V et al. | โ | 2018 | โ |
| Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register. | Hilker R et al. | โ | 2018 | โ |
| Hot Genes in Schizophrenia: How Clinical Datasets Could Help to Refine their Role. | Porcelli S et al. | โ | 2018 | โ |
| Identification of miR-22-3p, miR-92a-3p, and miR-137 in peripheral blood as biomarker for schizophrenia. | Ma J et al. | โ | 2018 | โ |
| Identification of shared genetic variants between schizophrenia and lung cancer. | Zuber V et al. | โ | 2018 | โ |
| Imaging and Genetic Biomarkers Predicting Transition to Psychosis. | Hunter SA et al. | โ | 2018 | โ |
| Imaging genetics of schizophrenia in the post-GWAS era. | Arslan A | โ | 2018 | โ |
| Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia. | Okazaki S et al. | โ | 2018 | โ |
| Induced Pluripotent Stem Cells Reveal Common Neurodevelopmental Genome Deprograming in Schizophrenia. | Narla ST et al. | โ | 2018 | โ |
| Interaction between BDNF and TNF-ฮฑ genes in schizophrenia. | Zhang Y et al. | โ | 2018 | โ |
| Interaction between compound genetic risk for schizophrenia and high birth weight contributes to social anhedonia and schizophrenia in women. | Liuhanen J et al. | โ | 2018 | โ |
| Investigation of chromosome Y loss in men with schizophrenia. | Hirata T et al. | โ | 2018 | โ |
| <i>VRK2</i>, a Candidate Gene for Psychiatric and Neurological Disorders. | Li M et al. | โ | 2018 | โ |
| Leukocyte telomere length variation in different stages of schizophrenia. | Maurya PK et al. | โ | 2018 | โ |
| Meta-analysis of Cerebrospinal Fluid Cytokine and Tryptophan Catabolite Alterations in Psychiatric Patients: Comparisons Between Schizophrenia, Bipolar Disorder, and Depression. | Wang AK et al. | โ | 2018 | โ |
| Meta-analysis of GABRB2 polymorphisms and the risk of schizophrenia combined with GWAS data of the Han Chinese population and psychiatric genomics consortium. | Zhang T et al. | โ | 2018 | โ |
| microRNAs Sculpt Neuronal Communication in a Tight Balance That Is Lost in Neurological Disease. | Thomas KT et al. | โ | 2018 | โ |
| Multivariate Pattern Analysis of Genotype-Phenotype Relationships in Schizophrenia. | Zheutlin AB et al. | โ | 2018 | โ |
| Neural Mechanisms of Early-Life Social Stress as a Developmental Risk Factor for Severe Psychiatric Disorders. | Reinwald JR et al. | โ | 2018 | โ |
| No association between FOXP2 rs10447760 and schizophrenia in a replication study of the Chinese Han population. | Yin J et al. | โ | 2018 | โ |
| On variability & human consciousness. | Boutwell BB | โ | 2018 | โ |
| Overlapping and disease specific trait, response, and reflection impulsivity in adolescents with first-episode schizophrenia spectrum disorders or attention-deficit/hyperactivity disorder. | Jepsen JRM et al. | โ | 2018 | โ |
| Polygenic risk for schizophrenia affects working memory and its neural correlates in healthy subjects. | Krug A et al. | โ | 2018 | โ |
| Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls. | Shafee R et al. | โ | 2018 | โ |
| Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort. | Santoro ML et al. | โ | 2018 | โ |
| Polygenic signal for symptom dimensions and cognitive performance in patients with chronic schizophrenia. | Xavier RM et al. | โ | 2018 | โ |
| Polymorphism in schizophrenia risk gene <i>MIR137</i> is associated with the posterior cingulate Cortex's activation and functional and structural connectivity in healthy controls. | Zhang Z et al. | โ | 2018 | โ |
| Polymorphisms in the human serotonin receptor 1B (HTR1B) gene are associated with schizophrenia: a case control study. | Xia X et al. | โ | 2018 | โ |
| Post-GWAS in Psychiatric Genetics: A Developmental Perspective on the "Other" Next Steps. | Dick DM et al. | โ | 2018 | โ |
| Proline dehydrogenase gene (PRODH) polymorphisms and schizophrenia susceptibility: a meta-analysis. | Guo X et al. | โ | 2018 | โ |
| Protein-C Reactive as Biomarker Predictor of Schizophrenia Phases of Illness? A Systematic Review. | Orsolini L et al. | โ | 2018 | โ |
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| Quantitative DNA Methylation Analysis of DLGAP2 Gene using Pyrosequencing in Schizophrenia with Tardive Dyskinesia: A Linear Mixed Model Approach. | Li Y et al. | โ | 2018 | โ |
| Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility. | Yu Y et al. | โ | 2018 | โ |
| Recently evolved human-specific methylated regionsย are enriched in schizophrenia signals. | Banerjee N et al. | โ | 2018 | โ |
| Rigor and reproducibility in genetic research on eating disorders. | Hรผbel C et al. | โ | 2018 | โ |
| Should we be targeting sleep architecture to more effectively treat schizophrenia? | Luu B et al. | โ | 2018 | โ |
| Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy. | Iversen TSJ et al. | โ | 2018 | โ |
| Thalamic Reticular Dysfunction as a Circuit Endophenotype in Neurodevelopmental Disorders. | Krol A et al. | โ | 2018 | โ |
| The developing utility of zebrafish models of neurological and neuropsychiatric disorders: A critical review. | Fontana BD et al. | โ | 2018 | โ |
| The GABRB3 Polymorphism and its Association with Schizophrenia. | Liu Y et al. | โ | 2018 | โ |
| The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project. | Blokland GAM et al. | โ | 2018 | โ |
| The <i>DGCR5</i> long noncoding RNA may regulate expression of several schizophrenia-related genes. | Meng Q et al. | โ | 2018 | โ |
| The integrated landscape of causal genes and pathways in schizophrenia. | Ma C et al. | โ | 2018 | โ |
| The relationship between fine particulate matter (PM<sub>2.5</sub>) and schizophrenia severity. | Eguchi R et al. | โ | 2018 | โ |
| The role of cadherin genes in five major psychiatric disorders: A literature update. | Hawi Z et al. | โ | 2018 | โ |
| The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review. | Mistry S et al. | โ | 2018 | โ |
| Tracing Early Neurodevelopment in Schizophrenia with Induced Pluripotent Stem Cells. | Ahmad R et al. | โ | 2018 | โ |
| Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism. | St Clair D et al. | โ | 2018 | โ |
| Whole genome sequencing of 91 multiplex schizophrenia families reveals increased burden of rare, exonic copy number variation in schizophrenia probands and genetic heterogeneity. | Khan FF et al. | โ | 2018 | โ |
| ZNF804A Variation May Affect Hippocampal-Prefrontal Resting-State Functional Connectivity in Schizophrenic and Healthy Individuals. | Zhang Y et al. | โ | 2018 | โ |
| Aberrant perfusion and its connectivity within default mode network of first-episode drug-naรฏve schizophrenia patients and their unaffected first-degree relatives. | Cui LB et al. | โ | 2017 | โ |
| Abnormal Rich-Club Organization Associated with Compromised Cognitive Function in Patients with Schizophrenia and Their Unaffected Parents. | Zhao X et al. | โ | 2017 | โ |
| A Brief Assessment of Intelligence Decline in Schizophrenia As Represented by the Difference between Current and Premorbid Intellectual Quotient. | Ohi K et al. | โ | 2017 | โ |
| Accumulation of minor alleles and risk prediction in schizophrenia. | He P et al. | โ | 2017 | โ |
| ALDH2 Glu504Lys Confers Susceptibility to Schizophrenia and Impacts Hippocampal-Prefrontal Functional Connectivity. | Zheng F et al. | โ | 2017 | โ |
| Altered DLPFC-Hippocampus Connectivity During Working Memory: Independent Replication and Disorder Specificity of a Putative Genetic Risk Phenotype for Schizophrenia. | Schneider M et al. | โ | 2017 | โ |
| A novel rare variant R292H in RTN4R affects growth cone formation and possibly contributes to schizophrenia susceptibility. | Kimura H et al. | โ | 2017 | โ |
| A Polygenic Risk Score of glutamatergic SNPs associated with schizophrenia predicts attentional behavior and related brain activity in healthy humans. | Rampino A et al. | โ | 2017 | โ |
| Application of induced pluripotent stem cells to understand neurobiological basis of bipolar disorder and schizophrenia. | Liu YN et al. | โ | 2017 | โ |
| A preliminary study of endocannabinoid system regulation in psychosis: Distinct alterations of CNR1 promoter DNA methylation in patients with schizophrenia. | D'Addario C et al. | โ | 2017 | โ |
| Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence. | Sauerzopf U et al. | โ | 2017 | โ |
| A Review of the Functional and Anatomical Default Mode Network in Schizophrenia. | Hu ML et al. | โ | 2017 | โ |
| Association between ErbB4 single nucleotide polymorphisms and susceptibility to schizophrenia: A meta-analysis of case-control studies. | Feng Y et al. | โ | 2017 | โ |
| Association of transcription factor 4 (TCF4) gene mRNA level with schizophrenia, its psychopathology, intelligence and cognitive impairments. | Alizadeh F et al. | โ | 2017 | โ |
| Basal ganglia and ventricle volume in first-episode psychosis. A family and clinical study. | Cuesta MJ et al. | โ | 2017 | โ |
| Challenges and opportunities for the development of new antipsychotic drugs. | Forray C et al. | โ | 2017 | โ |
| Chronic mild stress impairs latent inhibition and induces region-specific neural activation in CHL1-deficient mice, a mouse model of schizophrenia. | Buhusi M et al. | โ | 2017 | โ |
| Ciproxifan, a histamine H<sub>3</sub> receptor antagonist and inverse agonist, presynaptically inhibits glutamate release in rat hippocampus. | Lu CW et al. | โ | 2017 | โ |
| Cognitive clustering in schizophrenia patients, their first-degree relatives and healthy subjects is associated with anterior cingulate cortex volume. | Ohi K et al. | โ | 2017 | โ |
| Common developmental genome deprogramming in schizophrenia - Role of Integrative Nuclear FGFR1 Signaling (INFS). | Narla ST et al. | โ | 2017 | โ |
| Cross Talk: The Microbiota and Neurodevelopmental Disorders. | Kelly JR et al. | โ | 2017 | โ |
| De novo non-synonymous TBL1XR1 mutation alters Wnt signaling activity. | Nishi A et al. | โ | 2017 | โ |
| Differences in social functioning among patients with major psychiatric disorders: Interpersonal communication is impaired in patients with schizophrenia and correlates with an increase in schizotypal traits. | Yasuyama T et al. | โ | 2017 | โ |
| Effects of intranasal oxytocin on symptoms of schizophrenia: A multivariate Bayesian meta-analysis. | Williams DR et al. | โ | 2017 | โ |
| Electroconvulsive therapy-induced brain functional connectivity predicts therapeutic efficacy in patients with schizophrenia: a multivariate pattern recognition study. | Li P et al. | โ | 2017 | โ |
| Epigenomics of Major Depressive Disorders and Schizophrenia: Early Life Decides. | Hoffmann A et al. | โ | 2017 | โ |
| Evaluation of European Schizophrenia GWAS Loci in Asian Populations via Comprehensive Meta-Analyses. | Xiao X et al. | โ | 2017 | โ |
| Exome array analysis suggests an increased variant burden in families with schizophrenia. | McCarthy NS et al. | โ | 2017 | โ |
| Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance. | Kos MZ et al. | โ | 2017 | โ |
| Expert and self-assessment of lifetime symptoms and diagnosis of major depressive disorder in large-scale genetic studies in the general population: comparison of a clinical interview and a self-administered checklist. | Martin J et al. | โ | 2017 | โ |
| Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits. | So HC et al. | โ | 2017 | โ |
| Familial Aggregation and Heritability of Schizophrenia and Co-aggregation of Psychiatric Illnesses in Affected Families. | Chou IJ et al. | โ | 2017 | โ |
| Familial and environmental influences on brain volumes in twins with schizophrenia. | Picchioni MM et al. | โ | 2017 | โ |
| Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity. | Kim MJ et al. | โ | 2017 | โ |
| Functional neuroimaging effects of recently discovered genetic risk loci for schizophrenia and polygenic risk profile in five RDoC subdomains. | Erk S et al. | โ | 2017 | โ |
| Genetic and Environmental Contributions to the Association Between Cannabis Use and Psychotic-Like Experiences in Young Adult Twins. | Nesvรฅg R et al. | โ | 2017 | โ |
| Genetic and Environmental Influences on Gambling: A Meta-Analysis of Twin Studies. | Xuan YH et al. | โ | 2017 | โ |
| Genetic Approaches to Understanding Psychiatric Disease. | Michaelson JJ | โ | 2017 | โ |
| Genetic Basis of Positive and Negative Symptom Domains in Schizophrenia. | Xavier RM et al. | โ | 2017 | โ |
| Genetic insights into the neurodevelopmental origins of schizophrenia. | Birnbaum R et al. | โ | 2017 | โ |
| Genetic loci associated with an earlier age at onset in multiplex schizophrenia. | Woolston AL et al. | โ | 2017 | โ |
| Genetic Overlap Between Schizophrenia and Developmental Psychopathology: Longitudinal and Multivariate Polygenic Risk Prediction of Common Psychiatric Traits During Development. | Nivard MG et al. | โ | 2017 | โ |
| Genetics of Depression: Progress at Last. | Mullins N et al. | โ | 2017 | โ |
| Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics. | Giegling I et al. | โ | 2017 | โ |
| Genetics of Schizophrenia: Overview of Methods, Findings and Limitations. | Henriksen MG et al. | โ | 2017 | โ |
| Genetic variants of dopamine D2 receptor impact heterodimerization with dopamine D1 receptor. | Bลasiak E et al. | โ | 2017 | โ |
| GSTM1/GSTT1 double-null genotype increases risk of treatment-resistant schizophrenia: A genetic association study in Brazilian patients. | Pinheiro DS et al. | โ | 2017 | โ |
| Impact of DRD2/ANKK1 and COMT Polymorphisms on Attention and Cognitive Functions in Schizophrenia. | Nkam I et al. | โ | 2017 | โ |
| Impact of Familial Loading on Prefrontal Activation in Major Psychiatric Disorders: A Near-Infrared Spectroscopy (NIRS) Study. | Ohi K et al. | โ | 2017 | โ |
| Influence of <i>CFH</i> gene on symptom severity of schizophrenia. | Zhang C et al. | โ | 2017 | โ |
| Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders. | Nguyen HT et al. | โ | 2017 | โ |
| INTERNEURONOPATHIES AND THEIR ROLE IN EARLY LIFE EPILEPSIES AND NEURODEVELOPMENTAL DISORDERS. | Katsarou AM et al. | โ | 2017 | โ |
| Intranasal Oxytocin May Improve High-Level Social Cognition in Schizophrenia, But Not Social Cognition or Neurocognition in General: A Multilevel Bayesian Meta-analysis. | Bรผrkner PC et al. | โ | 2017 | โ |
| Microvascular anomaly conditions in psychiatric disease. Schizophrenia - angiogenesis connection. | Katsel P et al. | โ | 2017 | โ |
| Modeling a linkage between blood transcriptional expression and activity in brain regions to infer the phenotype of schizophrenia patients. | Ibrahim EC et al. | โ | 2017 | โ |
| Modeling schizophrenia pathogenesis using patient-derived induced pluripotent stem cells (iPSCs). | Noh H et al. | โ | 2017 | โ |
| Modelling gene-environment interaction in first episodes of psychosis. | Bernardo M et al. | โ | 2017 | โ |
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| mtDNA Heteroplasmy in Monozygotic Twins Discordant for Schizophrenia. | Li H et al. | โ | 2017 | โ |
| Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia. | Leonenko G et al. | โ | 2017 | โ |
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| No association between dopamine D3 receptor gene Ser9Gly polymorphism (rs6280) and risk of schizophrenia: an updated meta-analysis. | Qi XL et al. | โ | 2017 | โ |
| No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes. | Johnson EC et al. | โ | 2017 | โ |
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| Pluripotent stem cells in neuropsychiatric disorders. | Soliman MA et al. | โ | 2017 | โ |
| Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia. | Papiol S et al. | โ | 2017 | โ |
| Possible role of rare variants in Trace amine associated receptor 1 in schizophrenia. | John J et al. | โ | 2017 | โ |
| Predicting Cognitive Executive Functioning with Polygenic Risk Scores for Psychiatric Disorders. | Benca CE et al. | โ | 2017 | โ |
| Predictors of change in social networks, support and satisfaction following a first episode psychosis: A cohort study. | Renwick L et al. | โ | 2017 | โ |
| Probing the Association between Early Evolutionary Markers and Schizophrenia. | Srinivasan S et al. | โ | 2017 | โ |
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| QKI6B mRNA levels are upregulated in schizophrenia and predict GFAP expression. | Farnsworth B et al. | โ | 2017 | โ |
| Replicated association between the European GWAS locus rs10503253 at CSMD1 and schizophrenia in Asian population. | Liu W et al. | โ | 2017 | โ |
| Risk factors for the existence of attention deficit hyperactivity disorder symptoms in children with autism spectrum disorders. | Lamanna AL et al. | โ | 2017 | โ |
| Role of 108 schizophrenia-associated loci in modulating psychopathological dimensions in schizophrenia and bipolar disorder. | Fabbri C et al. | โ | 2017 | โ |
| Role of CACNA1C gene polymorphisms and protein expressions in the pathogenesis of schizophrenia: a case-control study in a Chinese population. | Zhang SY et al. | โ | 2017 | โ |
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| Small non-coding RNA expression from anterior cingulate cortex in schizophrenia shows sex specific regulation. | Ragan C et al. | โ | 2017 | โ |
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| Identification of rare variants in KCTD13 at the schizophrenia risk locus 16p11.2. | Degenhardt F et al. | โ | 2016 | โ |
| Identification of RELN variation p.Thr3192Ser in a Chinese family with schizophrenia. | Zhou Z et al. | โ | 2016 | โ |
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| Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia. | Genovese G et al. | โ | 2016 | โ |
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| Lack of Association Between Dopamine Beta-Hydroxylase (DBH) 19-bp Insertion/Deletion Polymorphism and Risk of Schizophrenia. | Shakiba M et al. | โ | 2016 | โ |
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| Evidence for Association of Cell Adhesion Molecules Pathway and NLGN1 Polymorphisms with Schizophrenia in Chinese Han Population. | Zhang Z et al. | โ | 2015 | โ |
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