Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population.
paper
Cited
Public
- Authors
- Fry, Anna; Littlejohns, Thomas J; Sudlow, Cathie; Doherty, Nicola; Adamska, Ligia; Sprosen, Tim; Collins, Rory; Allen, Naomi E
- Year
- 2017
- Journal
- American journal of epidemiology
- PMID
- 28641372
- DOI
- 10.1093/aje/kwx246
- PMCID
- PMC5860371
The UK Biobank cohort is a population-based cohort of 500,000 participants recruited in the United Kingdom (UK) between 2006 and 2010. Approximately 9.2 million individuals aged 40-69 years who lived within 25 miles (40 km) of one of 22 assessment centers in England, Wales, and Scotland were invited to enter the cohort, and 5.5% participated in the baseline assessment. The representativeness of the UK Biobank cohort was investigated by comparing demographic characteristics between nonresponders and responders. Sociodemographic, physical, lifestyle, and health-related characteristics of the cohort were compared with nationally representative data sources. UK Biobank participants were more likely to be older, to be female, and to live in less socioeconomically deprived areas than nonparticipants. Compared with the general population, participants were less likely to be obese, to smoke, and to drink alcohol on a daily basis and had fewer self-reported health conditions. At age 70-74 years, rates of all-cause mortality and total cancer incidence were 46.2% and 11.8% lower, respectively, in men and 55.5% and 18.1% lower, respectively, in women than in the general population of the same age. UK Biobank is not representative of the sampling population; there is evidence of a "healthy volunteer" selection bias. Nonetheless, valid assessment of exposure-disease relationships may be widely generalizable and does not require participants to be representative of the population at large.
Rate of participation in the UK Biobank according to sex (A), age at recruitment (B), Townsend deprivation score (C), and region of residence (D), 2006β2010. For numerators and denominators, see Web Table 1. Participants were assigned a Townsend deprivation score corresponding to the output area of their residential postcode (most deprived: β₯2.00; average: β2.00 to 1.99; least deprived: <β2.00). UK, United Kingdom.
Comparison of smoking status in UK Biobank participants (recruited in 2006β2010) with data from the Health Survey for England (HSE) 2008 for men aged 45β54 years (A), women aged 45β54 years (B), men aged 55β64 years (C), and women aged 55β64 years (D). HSE estimates were weighted for nonresponse bias. The graph excludes 1,899 UK Biobank participants aged 45β64 years who had missing data on smoking status or responded βprefer not to answer.β Numbers of participants: A) UK Biobank, n = 62,004; HSE, n = 1,206; B) UK Biobank, n = 79,755; HSE, n = 1,233; C) UK Biobank, n = 94,907; HSE, n = 1,085; D) UK Biobank, n = 116,246; HSE, n = 1,123. See HSE 2010 (9) for further information about HSE data. UK, United Kingdom.
Comparison of mortality rates per 1,000 person-years, by age at death, for UK Biobank participants (recruited in 2006β2010) and the population of England and Wales in 2012 (data from the Office for National Statistics) for men (A) and women (B). Total number of deaths in UK Biobank participants aged 45β74 years: men, 8,291; women, 5,380. See United Kingdom Office for National Statistics (13) for further information about death registration data. UK, United Kingdom.
Comparison of incidence rates for all cancers (excluding nonmelanoma skin cancer) per 100,000 person-years, by age at cancer diagnosis, for UK Biobank participants (recruited in 2006β2010) and the population of England in 2012 (data from the Office for National Statistics) for men (A) and women (B). Total number of all incident cancers (excluding nonmelanoma skin cancer) in UK Biobank participants aged 45β74 years: men, 11,436; women, 10,592. See United Kingdom Office for National Statistics (14) for further information about cancer registration data. UK, United Kingdom.
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| Plasma n6 polyunsaturated fatty acid levels and risk for dementia: a prospective observational study from the United Kingdom Biobank. | Sala-Vila A et al. | β | 2026 | β |
| Plasma proteomic signature of frailty in 50,506 adults. | Jia X et al. | β | 2026 | β |
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| Prevalence of deleterious variants in cardiomyopathy genes in early-onset atrial fibrillation. | Vad OB et al. | β | 2026 | β |
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| Prostate Cancer, Genetic Susceptibility, and Risk of Chronic Non-Urological Complications. | Helfand BT et al. | β | 2026 | β |
| Psychiatric disorders associated with increased risk of colorectal cancer in the UK biobank cohort. | Wang Z et al. | β | 2026 | β |
| Public Trust, Private Data: Four Considerations for the Future of Health. | Dasgupta N et al. | β | 2026 | β |
| Refined physical activity recommendations considering cardiovascular disease risk stratification: a cohort study. | Yuan C et al. | β | 2026 | β |
| Religious and Spiritual Behaviors Correlated with Mental and Physical Well-Being Among American Muslims within the Twin Cities. | Alamgir A et al. | β | 2026 | β |
| Representativeness of the Danish Blood Donor Study relative to the general population: a cross-sectional assessment. | TrΓ¦holt J et al. | β | 2026 | β |
| Reproducibility and associated regression dilution bias of accelerometer-derived physical activity and sleep in UK Biobank. | Zisou C et al. | β | 2026 | β |
| Reproductive factors, exogenous hormone use and risk of migraine among women: Results from UK Biobank. | Wang N et al. | β | 2026 | β |
| Residual inflammatory risk as a predictor of cardiometabolic multi-morbidity: results from three prospective cohorts. | Wang S et al. | β | 2026 | β |
| Right and Left Atrial Dysfunction as Independent Cardiovascular Risk Factors: A UK Biobank Study. | Yogeswaran V et al. | β | 2026 | β |
| Risk factor profiles for infections in individuals with type 2 diabetes: a prospective cohort study. | Yu HC et al. | β | 2026 | β |
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| Scanning the Horizon of Sociogenomics: an Assessment of the Development and Growth of Polygenic Indices for Social and Behavioral Traits. | Canter C et al. | β | 2026 | β |
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| Self-Reported Pharmacogenetic Medication Use in the Our Future Health Cohort. | Dixon P et al. | β | 2026 | β |
| Serological evidence linking viral infections to incident risk of hip and knee osteoarthritis. | Fang J et al. | β | 2026 | β |
| Sex differences in the experience of pain in the UK Biobank cohort study. | Luo J et al. | β | 2026 | β |
| Sex-specific associations of SHBG, testosterone, and obesity with cholecystectomy risk: a population-based cohort study. | Lyu JQ et al. | β | 2026 | β |
| Sex-specific interaction effects of Syntaxin 1A coexpression network and childhood trauma on adult depressive symptoms. | Arcego DM et al. | β | 2026 | β |
| Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancement. | Tse KYK et al. | β | 2026 | β |
| Social isolation and 59 common health conditions: insights from observational and genetics analyses. | Ai S et al. | β | 2026 | β |
| Social isolation, loneliness, genetic susceptibility, and the hazard of incident osteoporosis. | Zhou J et al. | β | 2026 | β |
| Socioeconomic status and suicidal behaviour in the UK Biobank: prospective cohort study on effect modifiers. | Sarkar C et al. | β | 2026 | β |
| Systematic assessment of obesity-related risk factors in renal cancer etiology: A longitudinal risk and Mendelian randomization analysis. | Alcala K et al. | β | 2026 | β |
| Temperatures around conception affect metabolic health in adulthood. | MΓΌnz TS et al. | β | 2026 | β |
| The association between a pro-inflammatory diet and brain age in middle-aged and older adults. | Dunk MM et al. | β | 2026 | β |
| The association of Alzheimer's disease genetic risk with social connectedness in middle- and older ages. | Zimmerman SC et al. | β | 2026 | β |
| The current state of polygenic scores for the development of lung cancer: a systematic review and validation in UK Biobank. | Galal B et al. | β | 2026 | β |
| The epidemiology of cubital tunnel syndrome: a UK Biobank case-control study. | Lucey M et al. | β | 2026 | β |
| The future of pharmacogenomics in cardiovascular medicine. | Danielli M et al. | β | 2026 | β |
| The genetic architecture of postoperative delirium after major surgery and its relationship with nonpostoperative neurocognitive conditions: A genome-wide association study. | Armstrong RA et al. | β | 2026 | β |
| The genetic landscape of human functional brain connectivity. | Maciel BA et al. | β | 2026 | β |
| The heterogeneous treatment effects of statins on dementia: a target trial emulation with causal machine learning using integrated genetic and real-world data. | Lai Y et al. | β | 2026 | β |
| The landscape of hereditary haemochromatosis risk and diagnosis across the British Isles and Ireland. | Kerr SM et al. | β | 2026 | β |
| The Mediating Effect of 24-Hour Movement Behaviors on Mortality Risk in Chronic Kidney Disease: A Compositional Mediation and Life Expectancy Analysis. | Wang Z et al. | β | 2026 | β |
| The presymptomatic and early manifestations of semantic dementia. | Whiteside DJ et al. | β | 2026 | β |
| The Prime Diet Quality Score (PDQS), chronic disease and cause-specific mortality in UK Biobank: a prospective study. | Kronsteiner-Gicevic S et al. | β | 2026 | β |
| Thinking Outside the Individual Box-A Communitarian Approach to Bioethics for Biorepositories. | Mayne ES | β | 2026 | β |
| Thoughts on risk-stratified vigorous physical activity thresholds in cardiovascular prevention. | Lin B et al. | β | 2026 | β |
| UK Biobank at 20 - a growing, global resource for dementia research. | Matthews PM et al. | β | 2026 | β |
| UK Biobank-centric advances in brain age prediction: a comprehensive review. | Li Y et al. | β | 2026 | β |
| Ultra-processed food consumption and incident autoimmune-related hypothyroidism: a sex-stratified prospective analysis from the UK Biobank. | Liu D et al. | β | 2026 | β |
| Uncovering plasma protein biomarkers linked to depression: A differential abundance analysis and Mendelian randomization using large-scale data. | Abebe E et al. | β | 2026 | β |
| Unraveling the anxiety-gastritis connection: A population-based real-world clinical investigation. | Guo Y et al. | β | 2026 | β |
| Unveiling the Burden of Steatotic Liver Disease: Mortality Risks by Subtype and Fibrosis Stage in a Nationwide Cohort. | Feng Q et al. | β | 2026 | β |
| UV-induced immune modulation in the lung niche slows cancer progression. | Maliah A et al. | β | 2026 | β |
| Vigorous intermittent lifestyle physical activity (VILPA) and mortality risk among US adults: a wearables-based national cohort study. | Koemel NA et al. | β | 2026 | β |
| 25-Hydroxyvitamin D Status and Its Predictors in Greek and Cypriot Subsets of the UK Biobank Cohort. | Kontea FE et al. | β | 2025 | β |
| A Case for estradiol: younger brains in women with earlier menarche and later menopause. | Luders E et al. | β | 2025 | β |
| Accelerated aging as a mediator of the association between co-exposure to multiple air pollutants and risk of chronic kidney disease. | Zhang S et al. | β | 2025 | β |
| Accelerated biological aging and incident degenerative valvular heart disease: Findings from 408,783 UK Biobank participants. | Lin C et al. | β | 2025 | β |
| Accelerated biological aging and risk of inflammatory bowel disease: A prospective study from 401,013 participants. | Cao B et al. | β | 2025 | β |
| Accelerated retinal ageing and multimorbidity in middle-aged and older adults. | Chen R et al. | β | 2025 | β |
| Accelerometer-based physical activity, air pollution and risk of dementia subtypes: a prospective study using UK biobank. | Zhang Y et al. | β | 2025 | β |
| Accelerometer-derived physical activity patterns and risk of incident gout: a prospective cohort study of 97,387 UK Biobank participants. | Wang Q et al. | β | 2025 | β |
| Accelerometer-Derived Physical Activity, Sedentary Behavior, and the Risk of Depression and Anxiety in Middle-aged and Older Adults: A Prospective Cohort Study of 71,556 UK Biobank Participants. | Yu K et al. | β | 2025 | β |
| Accelerometer-derived "weekend warrior" physical activity, genetic susceptibility, and risk of depression and anxiety: The UK Biobank study. | Liu Y et al. | β | 2025 | β |
| Accelerometer-derived "weekend warrior" physical activity pattern and incident type 2 diabetes. | Cao Z et al. | β | 2025 | β |
| Accelerometer-measured chronoactivity and type 2 diabetes risk: A prospective study in UK Biobank participants. | Feng Q et al. | β | 2025 | β |
| Accelerometer-measured moderate-to-vigorous physical activity is associated with reduced risk of bowel resection and mortality in inflammatory bowel disease: a prospective cohort study. | He Z et al. | β | 2025 | β |
| Accelerometer-Measured Physical Activity and Neuroimaging-Driven Brain Age. | Chen H et al. | β | 2025 | β |
| Accelerometer-Measured Sedentary Behavior and Risk of Future Cardiovascular Disease. | Ajufo E et al. | β | 2025 | β |
| Accelerometer-measured weekend catch-up sleep and incident dementia: A prospective cohort study. | Chen H et al. | β | 2025 | β |
| A cohort study reveals shared and distinct serum metabolic biomarkers for major adverse cardiovascular events in middle-aged and older adults. | Ren Y et al. | β | 2025 | β |
| A comparison of partner resemblance trends across putative same-sex and opposite-sex couples in the UK biobank. | Horwitz TB et al. | β | 2025 | β |
| A comprehensive exploration of the impact and contribution of polygenic risk score on age at onset of 30 complex diseases. | Liu Y et al. | β | 2025 | β |
| A computational framework for defining and validating reproducible phenotyping algorithms of 313 diseases in the UK Biobank. | Torralbo A et al. | β | 2025 | β |
| Acyclic graphs to define models of relationships between human cytomegalovirus, cardiovascular disease and all-cause mortality in UK Biobank. | Doorly R et al. | β | 2025 | β |
| Adapting the BOADICEA breast and ovarian cancer risk models for the ethnically diverse UK population. | Ficorella L et al. | β | 2025 | β |
| Adding salt to foods and risk of metabolic dysfunction-associated steatotic liver disease and other chronic liver diseases. | Zhang S et al. | β | 2025 | β |
| Adherence to a Healthful Plant-Based Diet and Risk of Chronic Kidney Disease Among Individuals with Diabetes. | Thompson AS et al. | β | 2025 | β |
| Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis. | Hazelwood E et al. | β | 2025 | β |
| Adiposity, mortality, and disease risk: insights from bioimpedance analysis and magnetic resonance imaging. | Gan Q et al. | β | 2025 | β |
| Adverse childhood experiences, mental distress, and autoimmune disease in adult women: findings from two large cohort studies. | KΓΆhler-Forsberg O et al. | β | 2025 | β |
| Adverse experiences in childhood and young adulthood, genetic susceptibility, and neurodegenerative disease incidence: a lifespan analysis. | Li J et al. | β | 2025 | β |
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| A hypothesis-free approach to identifying potential effects of relative age in school year: an instrumental variable phenome-wide association study in the UK Biobank. | de Lange MA et al. | β | 2025 | β |
| A hypothetical intervention on the use of hearing aids for the risk of dementia in people with hearing loss in UK Biobank. | Mur J et al. | β | 2025 | β |
| A Hypothetical PM2.5 Intervention for the Risk of Hospitalization for Cardiovascular Diseases. | Lin C et al. | β | 2025 | β |
| Alcohol consumption and incident heart failure in men and women. | Qin H et al. | β | 2025 | β |
| A lightweight generative model for interpretable subject-level prediction. | Mauri C et al. | β | 2025 | β |
| Allostatic load and risk of prostate cancer in UK Biobank. | Shen J et al. | β | 2025 | β |
| Alpha-1 antitrypsin Pi*MZ variant increases the risk of liver disease progression in MASLD and MASH. | Jermy B et al. | β | 2025 | β |
| Alzheimer's Disease polygenic risk, the plasma proteome, and dementia incidence among UK older adults. | Beydoun MA et al. | β | 2025 | β |
| A Machine Learning Prediction Model to Identify Individuals at Risk of 5-Year Incident Stroke Based on Retinal Imaging. | Govindaiah A et al. | β | 2025 | β |
| American Life in Realtime: Benchmark, publicly available person-generated health data for equity in precision health. | Chaturvedi RR et al. | β | 2025 | β |
| Amount and intensity of daily total physical activity, step count and risk of incident cancer in the UK Biobank. | Shreves AH et al. | β | 2025 | β |
| A multi-omics Mendelian randomization study identifies new therapeutic targets for alcohol use disorder and problem drinking. | Rosoff DB et al. | β | 2025 | β |
| A multiperspective investigation of the underrepresentation of minoritized ethnic participants in dementia research and proposed strategies to improve inclusive recruitment practices. | Marchant NL et al. | β | 2025 | β |
| An Alternatively Translated Isoform of PPARG Suggests AF-1 Domain Inhibition as an Insulin Sensitization Target. | Du X et al. | β | 2025 | β |
| Anxiety disorder, depression and coronary artery disease: associations and modification by genetic susceptibility. | Nakada S et al. | β | 2025 | β |
| A phenome-wide association study of genetically determined nicotine metabolism reveals novel links with health-related outcomes. | Buchwald J et al. | β | 2025 | β |
| APOE Genotype and Statin Response: Evidence From the UK Biobank and All of Us Program. | Asiimwe IG et al. | β | 2025 | β |
| A prospective protocol for remotely investigating brain-behaviour-genetics associations in adolescent patients in a paediatric health system with pre-existing clinical brain MRIs. | Mercedes L et al. | β | 2025 | β |
| A prospective study of eating disorders and risk of rheumatoid arthritis. | Chen J et al. | β | 2025 | β |
| A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia. | Ho FK et al. | β | 2025 | β |
| A proteomic signature of healthspan. | Kuo CL et al. | β | 2025 | β |
| Are associations of adulthood overweight and obesity with all-cause mortality, cardiovascular disease, and obesity-related cancer modified by comparative body weight at age 10 years in the UK Biobank study? | Johnson W et al. | β | 2025 | β |
| Artificial Intelligence-Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms. | Dhingra LS et al. | β | 2025 | β |
| Artificial Intelligence-Enhanced Electrocardiography for Prediction of Incident Hypertension. | Sau A et al. | β | 2025 | β |
| A simulation study comparing anticholinergic drug use with polypharmacy for risk of death, dementia, and delirium in UK Biobank. | Mur J et al. | β | 2025 | β |
| Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research. | Cai N et al. | β | 2025 | β |
| Assessment of Brain Morphological Abnormalities and Neurodevelopmental Risk Copy Number Variants in Individuals from the UK Biobank. | Azidane S et al. | β | 2025 | β |
| Association analysis of blood pressure with incident risks for thoracic and abdominal aortic aneurysms: an observational study of the UK Biobank cohort. | Lu K et al. | β | 2025 | β |
| Association between accelerometer-measured physical activity, genetic risk, and incident type 2 diabetes: A prospective cohort study. | Pan Y et al. | β | 2025 | β |
| Association between adult education, brain volume and dementia risk: longitudinal cohort study of UK Biobank participants. | Jin J et al. | β | 2025 | β |
| Association between adult-onset hearing loss and dementia biomarkers: A systematic review. | Lasica AB et al. | β | 2025 | β |
| Association between a healthy lifestyle and dementia in older adults with obesity: A prospective study in the UK biobank. | Wang J et al. | β | 2025 | β |
| Association between allostatic load and accelerated white matter brain aging: findings from the UK Biobank. | Feng L et al. | β | 2025 | β |
| Association between cardiovascular-kidney-metabolic syndrome, lifestyle, and all-cause and cause-specific mortality: a prospective cohort study. | Wang M et al. | β | 2025 | β |
| Association Between Chronic Pain and Risk of Glaucoma: A Prospective Cohort Study. | Chen J et al. | β | 2025 | β |
| Association between coffee and tea consumption and the risk of macrovascular complications in type 2 diabetes: a UK Biobank cohort study. | Ma T et al. | β | 2025 | β |
| Association between device-based measured physical activity timing and depression risk: a prospective cohort study of UK Biobank participants. | Albalak G et al. | β | 2025 | β |
| Association Between Early-Life and Premorbid Measurements of Body Composition and Risk of Motor Neuron Disease: A Prospective Cohort Study in the UK Biobank. | Joyce EE et al. | β | 2025 | β |
| Association between frailty and the progression trajectories of stroke and dementia comorbidity: insights from observational and genetic analyses. | Chen D et al. | β | 2025 | β |
| Association between genetic liability to physical health conditions and comorbidities in individuals with severe mental illness: an analysis of two cross-sectional observational studies in the UK. | Kappel DB et al. | β | 2025 | β |
| Association between glucosamine use and albuminuria in the UK: a cohort and Mendelian randomisation study. | Hayward SJ et al. | β | 2025 | β |
| Association between habitual adherence to the planetary health diet and mortality and major chronic disease risk among UK Biobank participants. | Karavasiloglou N et al. | β | 2025 | β |
| Association between hospital-treated infectious diseases and risk of neurodegenerative disease among patients with prediabetes and diabetes: A prospective cohort study in UK Biobank. | Wang J et al. | β | 2025 | β |
| Association between leukocyte telomere length and incident glaucoma: A prospective UK biobank study. | Yu J et al. | β | 2025 | β |
| Association between long-term benzene exposure and inflammatory bowel disease in a national cohort: The modifying effect of genetic susceptibility. | Xiao ZH et al. | β | 2025 | β |
| Association between multiple complications of pregnancy and risk of cardiovascular disease in a large cohort. | Li J et al. | β | 2025 | β |
| Association between obesity indexes and chronic kidney disease risk: a double-cohort prospective study in the Binhai and UK Biobank. | Gao S et al. | β | 2025 | β |
| Association Between Physical Activity and Memory Function: The Role of Brain Structural Markers in a Cross-Sectional Study. | Wu X et al. | β | 2025 | β |
| Association Between Plasma Metabolomic Profile and Machine Learning-Based Brain Age. | Li Y et al. | β | 2025 | β |
| Association between red blood cell distribution width and genetic risk in patients with rheumatoid arthritis: a prospective cohort study and Mendelian randomization analysis. | Chen M et al. | β | 2025 | β |
| Association Between Rheumatoid Arthritis and the Risk of Incident Degenerative Valvular Heart Disease: Evidence From a Prospective Cohort Study. | Wang Z et al. | β | 2025 | β |
| Association between triglyceride-glucose related indicators, genetic risk, and incident breast cancer among postmenopausal women in UK Biobank. | Li Z et al. | β | 2025 | β |
| Association Between Trunk Fat Mass Index and Diabetes in a Multinational Population. | Ogbonnaya C et al. | β | 2025 | β |
| Association between visceral adiposity index and cancer risk in the UK Biobank cohort. | Parra-Soto S et al. | β | 2025 | β |
| Association between wearable device-measured weekend catch-up sleep and brain health in UK Biobank participants. | Zheng Y et al. | β | 2025 | β |
| Association of 37 markers of ultra-processing with all-cause mortality: a prospective cohort study in the UK Biobank. | Krost KM et al. | β | 2025 | β |
| Association of accelerated phenotypic aging, genetic risk, and lifestyle with progression of type 2 diabetes: a prospective study using multi-state model. | Pan L et al. | β | 2025 | β |
| Association of accelerated phenotypic aging, lifestyle and genetic risk with progression of cardiometabolic multimorbidity: a multi-state model analysis. | Shi Y et al. | β | 2025 | β |
| Association of accelerometer-derived physical activity with all-cause and cause-specific mortality among individuals with cardiovascular diseases: a prospective cohort study. | Cao Z et al. | β | 2025 | β |
| Association of childhood-to-adulthood body size change with cancer risk: UK Biobank prospective cohort. | Mandic M et al. | β | 2025 | β |
| Association of clonal hematopoiesis of indeterminate potential with cardiometabolic multimorbidity progression and mortality: a prospective study of UK Biobank. | Zuo C et al. | β | 2025 | β |
| Association of genetically predicted levels of circulating blood lipids with coronary artery disease incidence. | Manikpurage HD et al. | β | 2025 | β |
| Association of habitual glucosamine use with risk of microvascular complications among individuals with type 2 diabetes: a prospective cohort study in UK biobank. | Cheng ZJ et al. | β | 2025 | β |
| Association of heel bone mineral density with incident dementia among ageing adults: a population-based study from the UK Biobank. | Lu J et al. | β | 2025 | β |
| Association of Income Inequality and Sleep Duration With Cardiovascular Outcomes in China and the UK. | Li C et al. | β | 2025 | β |
| Association of Leucocyte Telomere Length With Stroke, Dementia, and Late-Life Depression: The Role of Modifiable Risk Factors. | Kimball TN et al. | β | 2025 | β |
| Association of life's essential 8 and inflammatory biomarkers with nutritional anemia in UK adults. | Wang J et al. | β | 2025 | β |
| Association of Life's Essential 8 with incidence of heart failure modified by depressive symptoms: a prospective cohort study from UK Biobank. | Hu W et al. | β | 2025 | β |
| Association of loneliness and social isolation with excess risk of cardiovascular events in people with obesity: a prospective cohort study. | Zhou Y et al. | β | 2025 | β |
| Association of multimorbidity and disease clusters with neuroimaging and cognitive outcomes in UK Biobank. | Abid SUA et al. | β | 2025 | β |
| Association of Non-Insulin-Based Insulin Resistance Indices With Risk of Incident Valvular Heart Disease: Results From the UK Biobank Cohort Study. | Zhang Z et al. | β | 2025 | β |
| Association of pancreas fat fraction with adverse kidney and cardiovascular outcomes. | Thomas P et al. | β | 2025 | β |
| Association of Pancreas Volume With Adverse Clinical Outcomes. | Thomas P et al. | β | 2025 | β |
| Association of physical activity, cardiorespiratory fitness, grip strength, and grip strength asymmetry with incident musculoskeletal disorders in 406,080 White adults. | Yu Y et al. | β | 2025 | β |
| Association of polysocial risk score, cardiovascular health status, and the risk of premature mortality: Findings from the UK Biobank. | Shen W et al. | β | 2025 | β |
| Association of Pre-Diagnostic Clonal Hematopoiesis of Indeterminate Potential With Prognosis Among Patients With Cancer. | Liu X et al. | β | 2025 | β |
| Association of sugar intake with incident dementia in the UK Biobank: a prospective cohort study. | Che Y et al. | β | 2025 | β |
| Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption with Chronic Liver Disease and Liver-Related Events: A Large Prospective Cohort Study. | Li Y et al. | β | 2025 | β |
| Association of sugar-sweetened, artificially sweetened, and unsweetened tea with all-cause and cause-specific mortality: a prospective cohort study in UK biobank. | Lin Z et al. | β | 2025 | β |
| Association of sweetened beverage intake with incident risk of breast cancer: a prospective cohort study. | Huang J et al. | β | 2025 | β |
| Association of walking volume and intensity with incident gout: a population-based cohort study. | Wu Z et al. | β | 2025 | β |
| Associations Between Ambient Air Pollution and Five Common Vision-Threatening Ocular Diseases in Middle-Aged and Older Adults: A Large Prospective Cohort Study. | Wang Z et al. | β | 2025 | β |
| Associations between an inflammatory diet index and nonunion: a prospective study of 172,839 UK biobank participants. | Su J et al. | β | 2025 | β |
| Associations between childhood maltreatment, peripheral immune biomarkers, and psychiatric symptoms in adults: A cohort study of over 138,000 participants. | Jiang W et al. | β | 2025 | β |
| Associations between endogenous sex hormones and multisite chronic musculoskeletal pain. | Kifle ZD et al. | β | 2025 | β |
| Associations between IL-6 and trajectories of depressive symptoms across the life course: Evidence from ALSPAC and UK Biobank cohorts. | Edmondson-Stait AJ et al. | β | 2025 | β |
| Associations between lifestyle, malnutrition, and health risks in a comprehensive population-based analysis. | Banck MA et al. | β | 2025 | β |
| Associations between multiple ambient air pollutants, genetic risk, and incident mental disorders: An interaction study in the UK population. | Yao XI et al. | β | 2025 | β |
| Associations between physical activity and brain structure in a large community cohort. | La Hood A et al. | β | 2025 | β |
| Associations Between Plasma Omega-3 and Fish Oil Use With Risk of Atrial Fibrillation in the UK Biobank. | O'Keefe E et al. | β | 2025 | β |
| Associations between road, rail and aircraft traffic noise with cognitive function in the UK Biobank cohort. | Havyarimana E et al. | β | 2025 | β |
| Associations between testosterone and future PTSD symptoms among middle age and older UK residents. | Shen H et al. | β | 2025 | β |
| Associations of Accelerated Biological Aging With Dementia and the Mediation Role of Brain Structure: Findings From a Longitudinal Study. | Bo Y et al. | β | 2025 | β |
| Associations of accelerometer-derived moderate-to-vigorous physical activity and atrioventricular block in a healthy elderly population. | Chung HG et al. | β | 2025 | β |
| Associations of age at menopause, bilateral oophorectomy, hysterectomy and hormone replacement therapy with glycaemia and risk of dementia: a study based on the population-based UK Biobank cohort. | Geraets A et al. | β | 2025 | β |
| Associations of asthma with cardiometabolic diseases and multimorbidity: A cohort study in the UK Biobank. | Lin J et al. | β | 2025 | β |
| Associations of body fat and inflammation with non-communicable chronic diseases and mortality: a prospective cohort study of the UK Biobank. | Wiebe N et al. | β | 2025 | β |
| Associations of cachexia and frailty with amyotrophic lateral sclerosis. | Peters TL et al. | β | 2025 | β |
| Associations of Cardiovascular Health and New-Onset Age-Related Macular Diseases From UK Biobank. | Peng Y et al. | β | 2025 | β |
| Associations of clinical parameter-based accelerated aging, genetic predisposition with risk of chronic kidney disease and associated life expectancy: A prospective cohort study. | Zheng G et al. | β | 2025 | β |
| Associations of combined accelerated biological aging and genetic susceptibility with incidence of heart failure in a population-based cohort study. | Zhao H et al. | β | 2025 | β |
| Associations of Grip Strength Asymmetry With Multiple Health Outcomes. | Liu W et al. | β | 2025 | β |
| Associations of leucocyte subtypes and platelet parameters with kidney cancer risk in the UK Biobank cohort. | Christakoudi S et al. | β | 2025 | β |
| Associations of long-term exposure to nitrogen oxides with all-cause and cause-specific mortality. | Yang S et al. | β | 2025 | β |
| Associations of metabolic dysfunction-related fatty liver disease and dementia risk: A prospective study based on the UK biobank. | Geng C et al. | β | 2025 | β |
| Associations of modified triglyceride-glucose indices and the triglyceride/high-density lipoprotein ratio with all-cause and cause-specific mortality in the general population: an analysis of the UK biobank database. | Zhang Z et al. | β | 2025 | β |
| Associations of physical activity with the risks of osteoarthritis and subtypes : a population-based cohort study of UK Biobank data. | Gu H et al. | β | 2025 | β |
| Associations of plasma omega-6 and omega-3 fatty acids with overall and 19 site-specific cancers: A population-based cohort study in UK Biobank. | Zhang Y et al. | β | 2025 | β |
| Associations of protein intake with the risk of fractures: A prospective cohort study of UK biobank participants. | Yang H et al. | β | 2025 | β |
| Associations of residential greenness with incident vascular diseases in middle-aged and older adults: A large prospective cohort study. | Cheng B et al. | β | 2025 | β |
| Associations of Serum Testosterone and SHBG With Incident Fractures in Middle-aged to Older Men. | Grahnemo L et al. | β | 2025 | β |
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| Balancing the risk of major bleeding against vascular disease risk in people without atherosclerotic disease. | Hammami I et al. | β | 2025 | β |
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| Comparing Ancestry Standardization Approaches for a Transancestry Colorectal Cancer Polygenic Risk Score. | Rosenthal EA et al. | β | 2025 | β |
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| Copy Number Variations and Human Well-Being: Integrating Psychiatric, Physical, and Socioeconomic Perspectives. | Kushima I et al. | β | 2025 | β |
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| Data-driven discovery of midlife cardiometabolic profile associated with incident early-onset and late-onset dementia. | Li J et al. | β | 2025 | β |
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| Deep representation learning of electrocardiogram reveals biological insights in cardiac phenotypes and cardiovascular diseases. | Yeung MW et al. | β | 2025 | β |
| Defining a High-Quality Myalgic Encephalomyelitis/Chronic Fatigue Syndrome cohort in UK Biobank. | Samms GL et al. | β | 2025 | β |
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| Genetics and Socioeconomic Status: Some Preliminary Evidence on Mechanisms. | Carvalho LS | β | 2025 | β |
| Genetics, primary care records and lifestyle factors for short-term dynamic risk prediction of colorectal cancer: prospective study of asymptomatic and symptomatic UK Biobank participants. | Ip S et al. | β | 2025 | β |
| Genome-first determination of the prevalence and penetrance of eight germline myeloid malignancy predisposition genes: a study of two population-based cohorts. | Hendricks RM et al. | β | 2025 | β |
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| Genomic Ascertainment of CHEK2-Related Cancer Predisposition. | Kim SY et al. | β | 2025 | β |
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| High diversity of dietary flavonoid intake is associated with a lower risk of all-cause mortality and major chronic diseases. | Parmenter BH et al. | β | 2025 | β |
| Higher consumption of sugar-sweetened beverages is associated with an increased risk of endometrial cancer: a prospective cohort study of 92,777 women from the UK Biobank. | Yi K et al. | β | 2025 | β |
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| Hormone therapy and oral contraceptives in the risk of knee osteoarthritis: a prospective cohort study. | Wang J et al. | β | 2025 | β |
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| Identifying modifiable factors and their joint associations on late-onset schizophrenia risk in the UK Biobank: a prospective exposure-wide association study. | Jiang F et al. | β | 2025 | β |
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| Insights Into Causal Effects of Genetically Proxied Lipids and Lipid-Modifying Drug Targets on Cardiometabolic Diseases. | Fu L et al. | β | 2025 | β |
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| Investigating whether smoking and alcohol behaviours influence risk of type 2 diabetes using a Mendelian randomisation study. | Reed ZE et al. | β | 2025 | β |
| Is Metabolic Syndrome a Risk Factor for Skin Cancer? A UK Biobank Observational and Two-Sample Mendelian Randomization Study. | Black EAM et al. | β | 2025 | β |
| Is physical activity in polluted environments beneficial or detrimental to osteoporosis and osteoarthritis? A prospective cohort study. | Xiang L et al. | β | 2025 | β |
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| The impact of sleep on breast cancer-specific mortality:Β a Mendelian randomisation study. | Hayes BL et al. | β | 2025 | β |
| The lifetime accumulation of multimorbidity and its influence on dementia risk: a UK Biobank study. | Patel R et al. | β | 2025 | β |
| The metabolic vulnerability index as a novel tool for mortality risk stratification in a large-scale population-based cohort. | Li J et al. | β | 2025 | β |
| The plasma proteome of plant-based diets: Analyses of 2920 proteins in 49,615 people. | Tong TYN et al. | β | 2025 | β |
| The Polygenic Risk Score for Parkinson's Disease Is Associated with Becoming a Medical Doctor or Dentist. | Takeuchi H et al. | β | 2025 | β |
| The Promise and Pitfalls of Psychosocial Data in Cardiovascular Prevention. | Bhatti T | β | 2025 | β |
| The relationship between neuropsychiatric dimensions and markers of Parkinson's disease risk in the UK Biobank. | Attaallah B et al. | β | 2025 | β |
| The Relationships Between MASLD, Extrahepatic Multimorbidity, and All-Cause Mortality in the UK Biobank Cohort. | Feng Q et al. | β | 2025 | β |
| The role of cardiovascular disease as a mediator in mitigating the impact of ambient PM<sub>2.5</sub> on dementia risk. | Lin C et al. | β | 2025 | β |
| The role of greenspace in vitamin D status: cross-sectional, observational evidence from the UK Biobank. | Odebeatu CC et al. | β | 2025 | β |
| The role of Life's Crucial 9 in cardiovascular disease incidence and dynamic transitions to dementia. | Zhang Y et al. | β | 2025 | β |
| The Role of SLC39A8.p.(Ala391Thr) in Schizophrenia Symptom Severity and Cognitive Ability: Cross-Sectional Studies of Schizophrenia and the General UK Population. | Smart SE et al. | β | 2025 | β |
| The roles of lifestyle factors and genetic risk in the association between night shift work and cholelithiasis: a prospective cohort study. | He W et al. | β | 2025 | β |
| The synergy between life's essential 8 and muscle strength on cardiovascular disease risk. | Li L et al. | β | 2025 | β |
| The UK Biobank mental health enhancement 2022: Methods and results. | Davis KAS et al. | β | 2025 | β |
| Thyroid Disease and Amyotrophic Lateral Sclerosis. | Peters T et al. | β | 2025 | β |
| Total and regional fat-to-muscle mass ratio and risks of pan-cancer: a prospective cohort study. | Wang R et al. | β | 2025 | β |
| Total and Regional Fat-To-Muscle Mass Ratio in Relation to All-Cause and Cause-Specific Mortality in Men and Women. | Xu M et al. | β | 2025 | β |
| Transfer Learning Prediction of Early Exposures and Genetic Risk Score on Adult Obesity in Two Minority Cohorts. | Chen W et al. | β | 2025 | β |
| UK Biobank-A Unique Resource for Discovery and Translation Research on Genetics and Neurologic Disease. | Taylor H et al. | β | 2025 | β |
| UK Biobank data demonstrate long-term exposure to floods is a risk factor for incident dementia. | Wu Y et al. | β | 2025 | β |
| Ultra-processed food intake and brain health in middle-aged and older adults. | Gu J et al. | β | 2025 | β |
| Ultraprocessed foods consumption, inflammatory index levels, and risk of suicide attempt: findings from a prospective cohort study. | Wu Y et al. | β | 2025 | β |
| Understanding the Metabolic Fingerprint of Muscle Aging. | Chen LK | β | 2025 | β |
| Understanding the role of metabolic syndrome in prostate cancer risk: A UK Biobank prospective cohort study. | Lee SF et al. | β | 2025 | β |
| Unhealthful plant-based diet associates with frailty risk predominantly in men with low income from the UK Biobank cohort. | Schorr K et al. | β | 2025 | β |
| Unhealthy lifestyles accelerated aging andΒ consequential musculoskeletal morbidity: a critical appraisal. | Abedeen ZU et al. | β | 2025 | β |
| Unilateral Visual Impairment and Increased Mortality: TheΒ UK Biobank Cohort Study. | Fu C et al. | β | 2025 | β |
| Unlocking mental health insights with UK Biobank data: Past use and future opportunities. | Davis KAS et al. | β | 2025 | β |
| Updating the Scottish national cardiovascular risk score: ASSIGN version 2.0. | Welsh P et al. | β | 2025 | β |
| Urban-rural differences in anxiety and depression in the UK, New Zealand, and Norway. | Finnemann A et al. | β | 2025 | β |
| Use of dual-energy X-ray absorptiometry to evaluate variation in bone shape and alignment associated with radiographic knee osteoarthritis: Findings from a study of 19,053 individuals in UK Biobank. | Beynon RA et al. | β | 2025 | β |
| Use of genetic correlations to examine selection bias. | Shapland CY et al. | β | 2025 | β |
| Using Genomics to Develop Personalized Cardiovascular Treatments. | Sanghvi MM et al. | β | 2025 | β |
| Using Large Genomic Biobanks to Generate Insights into Genetic Kidney Disease. | Chang AR et al. | β | 2025 | β |
| Variable hyperthyroidism outcomes related to different treatment regimens: an analysis of UK Biobank data. | Elomaa K et al. | β | 2025 | β |
| Vascular cell adhesion molecule 1: a marker for atrial fibrillation and heart failure risk. | Baadsgaard JA et al. | β | 2025 | β |
| Walking Speed and Risk of Cancer in Two Prospective Cohort Studies. | Mak JKL et al. | β | 2025 | β |
| Wearable device-measured moderate to vigorous physical activity and risk of degenerative aortic valve stenosis. | Li Z et al. | β | 2025 | β |
| "Weekend warrior" physical activity pattern and risk of incident cancer. | LΓ³pez-Bueno R et al. | β | 2025 | β |
| Weekly Journal Scan: Machine learning, polygenic risk, and the next frontier in coronary artery disease prediction and prevention. | Liuzzo G et al. | β | 2025 | β |
| Weight-adjusted waist index outperforms other obesity indices for cardiovascular disease prediction in cardiovascular-kidney-metabolic syndrome: insights from UK biobank. | Wang T et al. | β | 2025 | β |
| Weighting health-related estimates in the GCAT cohort and the general population of Catalonia. | Blay N et al. | β | 2025 | β |
| What can we learn from an intersectionality-informed description of study participants? Results from the German National Cohort. | Jaehn P et al. | β | 2025 | β |
| What is normal age-related thigh muscle composition among 45- to 84-year-old adults from the UK Biobank study. | Anderson DB et al. | β | 2025 | β |
| When selection becomes selection bias. | Laugesen K et al. | β | 2025 | β |
| White matter microstructure in mid- to late adulthood is influenced by pathway-stratified polygenic risk for Alzheimer's disease. | Harrison JR et al. | β | 2025 | β |
| WHO guidelines on waist circumference and physical activity and their joint association with cancer risk. | Bohmann P et al. | β | 2025 | β |
| A 10-Year Longitudinal Study of Brain Cortical Thickness in People with First-Episode Psychosis Using Normative Models. | Berthet P et al. | β | 2024 | β |
| A cautionary tale for Alzheimer's disease GWAS by proxy. | Pedersen EM et al. | β | 2024 | β |
| Accelerated biological aging: unveiling the path to cardiometabolic multimorbidity, dementia, and mortality. | He Y et al. | β | 2024 | β |
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| Adherence to the Mediterranean diet is associated with reduced chronic pancreatitis risk: a longitudinal cohort study. | Zhou C et al. | β | 2024 | β |
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| Advances and prospects of multi-modal ophthalmic artificial intelligence based on deep learning: a review. | Wang S et al. | β | 2024 | β |
| Adverse Childhood Experiences and Later-Life Cognitive Aging: Persistent Methodological Challenges Limit the Evidence Base. | Kobayashi LC | β | 2024 | β |
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| Air pollutants and the risk of incident hepatobiliary diseases: A large prospective cohort study in the UK Biobank. | Cheng B et al. | β | 2024 | β |
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| Assessing the validity of a self-reported clinical diagnosis of schizophrenia. | Woolway GE et al. | β | 2024 | β |
| Associated risk and resilience factors of Alzheimer's disease in women with early bilateral oophorectomy: Data from the UK Biobank. | Calvo N et al. | β | 2024 | β |
| Association Between Body Composition Patterns, Cardiovascular Disease, and Risk of Neurodegenerative Disease in the UK Biobank. | Xu S et al. | β | 2024 | β |
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| Association between dietary magnesium intake and incident chronic kidney disease: a prospective observational cohort study. | Koh HB et al. | β | 2024 | β |
| Association between fish oil and glucosamine use and mortality in patients diagnosed with cancer: the role of the Life Essential 8 score and cancer prognosis. | Lam CS et al. | β | 2024 | β |
| Association between grip strength and walking pace with incidence of degenerative cervical myelopathy: a UK biobank observational study. | Chengkai L et al. | β | 2024 | β |
| Association between loneliness and incident atrial fibrillation across different genetic predisposition: findings from the UK Biobank. | Liu Z et al. | β | 2024 | β |
| Association between long-term exposure to low ambient PM<sub>2.5</sub> and cardiovascular hospital admissions: A UK Biobank study. | Vanoli J et al. | β | 2024 | β |
| Association between proton pump inhibitors and dementia risk: a Mendelian randomization study. | Xie K et al. | β | 2024 | β |
| Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort. | Sun Z et al. | β | 2024 | β |
| Association of cigarette smoking, smoking cessation with the risk of cardiometabolic multimorbidity in the UK Biobank. | Zhang S et al. | β | 2024 | β |
| Association of coffee consumption with cardiometabolic multimorbidity: A prospective cohort study in the UK biobank. | Sun D et al. | β | 2024 | β |
| Association of depression with severe non-alcoholic fatty liver disease: evidence from the UK Biobank study and Mendelian randomization analysis. | Zhou X et al. | β | 2024 | β |
| Association of Metabolomics With Incidence of Age-Related Macular Degeneration: The UK Biobank Study. | Yu J et al. | β | 2024 | β |
| Association of moderate alcohol intake with the risks of cirrhosis and steatotic liver disease: Results from a large population-based cohort study. | Xue H et al. | β | 2024 | β |
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| Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities. | Jawad MA et al. | β | 2024 | β |
| Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults. | Mohammad S et al. | β | 2024 | β |
| Association of ultraprocessed food consumption with risk of rheumatoid arthritis: a retrospective cohort study in the UK Biobank. | Zhao H et al. | β | 2024 | β |
| Association of whole-person eigen-polygenic risk scores with Alzheimer's disease. | Kharaghani A et al. | β | 2024 | β |
| Associations among dietary 1-carbon metabolism nutrients, genetic risk, and Alzheimer disease: a prospective cohort study. | Wang Y et al. | β | 2024 | β |
| Associations between Aircraft Noise, Sleep, and Sleep-Wake Cycle: Actimetric Data from the UK Biobank Cohort near Four Major Airports. | Gong X et al. | β | 2024 | β |
| Associations between Changes in Exposure to Air Pollutants due to Relocation and the Incidence of 14 Major Disease Categories and All-Cause Mortality: A Natural Experiment Study. | Chen G et al. | β | 2024 | β |
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| Associations of Serum Lipid Traits With Fracture and Osteoporosis: A Prospective Cohort Study From the UK Biobank. | Xiong X et al. | β | 2024 | β |
| Associations of sugar intake, high-sugar dietary pattern, and the risk of dementia: a prospective cohort study of 210,832 participants. | Zhang S et al. | β | 2024 | β |
| A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score (PRS) Release. | Thompson DJ et al. | β | 2024 | β |
| Brain age gap, dementia risk factors and cognition in middle age. | Stefaniak JD et al. | β | 2024 | β |
| Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations. | Moguilner S et al. | β | 2024 | β |
| Cardiovascular Disease, Genetic Susceptibility, and Risk of Psychiatric Disorders and Suicide Attempt: A Community-Based Matched Cohort Study Based on the UK Biobank. | Yang J et al. | β | 2024 | β |
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| Carotid plaque characteristics in the CREST-2 trial. | Lal BK et al. | β | 2024 | β |
| Causal evidence of the relationship between polycystic ovary syndrome and obstructive sleep apnea in European and East Asian populations: a two-sample Mendelian randomization study. | Liu X et al. | β | 2024 | β |
| Central Lean Mass Distribution and the Risks of All-Cause and Cause-Specific Mortality in 40,283 UK Biobank Participants. | Ding L et al. | β | 2024 | β |
| Characterising the genetic architecture of changes in adiposity during adulthood using electronic health records. | Venkatesh SS et al. | β | 2024 | β |
| Chronic Low-Grade Inflammation and Brain Structure in the Middle-Aged and Elderly Adults. | Bao Y et al. | β | 2024 | β |
| Chronic pain in multiple sites is associated with cardiovascular dysfunction: an observational UK Biobank cohort study. | Tian J et al. | β | 2024 | β |
| Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study. | Lu L et al. | β | 2024 | β |
| Clinical biomarker-based biological ageing and the risk of adverse outcomes in patients with chronic kidney disease. | Xiang H et al. | β | 2024 | β |
| Clonal hematopoiesis of indeterminate potential and the risk of pulmonary embolism: an observational study. | Liu Q et al. | β | 2024 | β |
| Cohort profile: DNA methylation in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) - recruitment and participant characteristics. | Potter C et al. | β | 2024 | β |
| Comparing Cadence vs. Machine Learning Based Physical Activity Intensity Classifications: Variations in the Associations of Physical Activity With Mortality. | Wei L et al. | β | 2024 | β |
| Comparison of blood-based liver fibrosis scores in the Mount Sinai Health System, MASLD Registry, and NHANES 2017-2020 study. | Chen R et al. | β | 2024 | β |
| Comparison of volumetric brain analysis in subjects with rheumatoid arthritis and ulcerative colitis. | Cox JG et al. | β | 2024 | β |
| Consumption of Total and Specific Alcoholic Beverages and Long-Term Risk of Gout Among Men and Women. | Lyu JQ et al. | β | 2024 | β |
| Contrasting association pattern of plasma low-density lipoprotein with white matter integrity in APOE4 carriers versus non-carriers. | Ye Z et al. | β | 2024 | β |
| Copy-number variants differ in frequency across genetic ancestry groups. | Schultz LM et al. | β | 2024 | β |
| Current best practices and future opportunities for reproducible findings using large-scale neuroimaging in psychiatry. | Jahanshad N et al. | β | 2024 | β |
| Daily-Life Walking Speed, Quality and Quantity Derived from a Wrist Motion Sensor: Large-Scale Normative Data for Middle-Aged and Older Adults. | Chan LLY et al. | β | 2024 | β |
| Decoding the weekend sleep dilemma: the health impacts of catching up on sleep. | Gao C et al. | β | 2024 | β |
| Development and validation of a lifetime prediction model for incident type 2 diabetes in patients with established cardiovascular disease: the CVD2DM model. | Helmink MAG et al. | β | 2024 | β |
| Device-measured weekend catch-up sleep, mortality, and cardiovascular disease incidence in adults. | Chaput JP et al. | β | 2024 | β |
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| Diet modifies the association between alcohol consumption and severe alcohol-related liver disease incidence. | Petermann-Rocha F et al. | β | 2024 | β |
| Disease Modules Associated with Unfavorable Sleep Patterns and Their Genetic Determinants: A Prospective Cohort Study of the UK Biobank. | Yang H et al. | β | 2024 | β |
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| Disease Trajectories from Healthcare Data: Methodologies, Key Results, and Future Perspectives. | JΓΈrgensen IF et al. | β | 2024 | β |
| Distinct and Overlapping Metabolites Associated with Visual Impairment and Cognitive Impairment. | Hu W et al. | β | 2024 | β |
| Distinct impact modes of polygenic disposition to dyslexia in the adult brain. | Soheili-Nezhad S et al. | β | 2024 | β |
| Diurnal timing of physical activity and risk of colorectal cancer in the UK Biobank. | Stein MJ et al. | β | 2024 | β |
| Earlier Age at Menopause, Plasma Metabolome, and Risk of Premature Mortality. | Yang Z et al. | β | 2024 | β |
| Effects of oral contraceptives and menopausal hormone therapy on the risk of rheumatoid arthritis: a prospective cohort study. | Hadizadeh F et al. | β | 2024 | β |
| Enhancing fairness in AI-enabled medical systems with the attribute neutral framework. | Hu L et al. | β | 2024 | β |
| Estimating cancer risk in carriers of Lynch syndrome variants in UK Biobank. | Fummey E et al. | β | 2024 | β |
| Ethnic Differences in Atrial Fibrillation inΒ the United Kingdom. | Frimodt-MΓΈller EK et al. | β | 2024 | β |
| Evaluating the relationship between glycemic control and bone fragility within the UK Biobank: observational and one-sample Mendelian randomization analyses. | Ghatan S et al. | β | 2024 | β |
| Evaluation of coverage, generalisability and validity of the U-CAN lymphoma biobank in Sweden: A comparison with nationwide registers. | Forsgren E et al. | β | 2024 | β |
| Exploration of first onsets of mania, schizophrenia spectrum disorders and major depressive disorder in perimenopause. | Shitomi-Jones LM et al. | β | 2024 | β |
| Exploring the causal effect between lipid-modifying drugs and idiopathic pulmonary fibrosis: a drug-target Mendelian randomization study. | Cai G et al. | β | 2024 | β |
| Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study. | Yu Y et al. | β | 2024 | β |
| Exposure to air pollution, genetic susceptibility, and prevalence of sarcopenia in the UK. | Liu X et al. | β | 2024 | β |
| Exposure to sugar rationing in the first 1000 days of life protected against chronic disease. | Gracner T et al. | β | 2024 | β |
| Facial aging, cognitive impairment, and dementia risk. | Xu X et al. | β | 2024 | β |
| Flavonoid-Rich Foods, Dementia Risk, and Interactions With Genetic Risk, Hypertension, and Depression. | Jennings A et al. | β | 2024 | β |
| Foods, dietary patterns, and risk of vascular dementia: a systematic review. | Griffiths A et al. | β | 2024 | β |
| Gene-Environment Interaction Between CYP1B1 and Oral Contraception on Frontal Fibrosing Alopecia. | Rayinda T et al. | β | 2024 | β |
| Genetic and Phenotypic Features of Schizophrenia in the UK Biobank. | Legge SE et al. | β | 2024 | β |
| Genetic architectures of the human hippocampus and those involved in neuropsychiatric traits. | Ning C et al. | β | 2024 | β |
| Genetic Heterogeneity Across Dimensions of Alcohol Use Behaviors. | Savage JE et al. | β | 2024 | β |
| Genetic predisposition, modifiable lifestyles, and their joint effects on human lifespan: evidence from multiple cohort studies. | Bian Z et al. | β | 2024 | β |
| Genetic susceptibility to chronic diseases leads to heart failure among Europeans: the influence of leukocyte telomere length. | Wong JYY et al. | β | 2024 | β |
| Genetic variation in circadian regulator gene <i>BMAL1</i> in psychiatric, psychological and cardiometabolic traits: a trans-ancestry UK Biobank study. | Daudali H et al. | β | 2024 | β |
| Genotype-First Approach Identifies an Association between rs28374544/FOG2<sup>S657G</sup> and Liver Disease through Alterations in mTORC1 Signaling. | Conlon DM et al. | β | 2024 | β |
| Glucagon-like peptide-1 receptor agonists and the risk of erectile dysfunction: a drug target Mendelian randomization study. | An H et al. | β | 2024 | β |
| Guidance for estimating penetrance of monogenic disease-causing variants in population cohorts. | Wright CF et al. | β | 2024 | β |
| Head motion in the UK Biobank imaging subsample: longitudinal stability, associations with psychological and physical health, and risk of incomplete data. | Ward J et al. | β | 2024 | β |
| Healthy eating patterns associated with reduced risk of inflammatory bowel disease by lowering low-grade inflammation: evidence from a large prospective cohort study. | Xia B et al. | β | 2024 | β |
| Healthy Lifestyle, Metabolic Signature, and Risk of Cardiovascular Diseases: A Population-Based Study. | Wang Y et al. | β | 2024 | β |
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| History of childhood maltreatment associated with hospitalization or death due to COVID-19: a cohort study. | Wang Y et al. | β | 2024 | β |
| How group structure impacts the numbers at risk for coronary artery disease: polygenic risk scores and nongenetic risk factors in the UK Biobank cohort. | Zhao J et al. | β | 2024 | β |
| ICMR-MDRF Diabetes Biosamples: Cohort profile. | Anjana RM et al. | β | 2024 | β |
| Identifying behaviour-related and physiological risk factors for suicide attempts in the UK Biobank. | Zhang B et al. | β | 2024 | β |
| Identifying combinations of long-term conditions associated with sarcopenia: a cross-sectional decision tree analysis in the UK Biobank study. | Hillman SJ et al. | β | 2024 | β |
| Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness. | Amelink JS et al. | β | 2024 | β |
| Individual and joint effects of diabetes and depression on incident cardiovascular diseases and all-cause mortality: Results from a population-based cohort study. | Tu Q et al. | β | 2024 | β |
| In or out of reach? Long-term trends in the reach of health assessments in the Swedish occupational setting. | Ekblom-Bak E et al. | β | 2024 | β |
| Integrating multiple kidney function markers to predict all-cause and cardiovascular disease mortality: prospective analysis of 366Β 758 UK Biobank participants. | Fujii R et al. | β | 2024 | β |
| Interpreting elevated liver blood test results through a genetic lens: A genome-wide association study. | Innes H et al. | β | 2024 | β |
| Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization. | Marchi M et al. | β | 2024 | β |
| Investigating the influence of oral contraceptive pill use on multiple sclerosis risk using UK Biobank data. | Nova A et al. | β | 2024 | β |
| In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? | Anderson JJ et al. | β | 2024 | β |
| Life Events and Incident Dementia: A Prospective Study of 493,787 Individuals Over 16 Years. | Karakose S et al. | β | 2024 | β |
| Life's Essential 8 and Poor Brain Health Outcomes in Middle-Aged Adults. | Clocchiatti-Tuozzo S et al. | β | 2024 | β |
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| Long-term cardiovascular risks associated with metabolic dysfunction-associated steatotic liver disease in inflammatory bowel disease patients. | Yu JT et al. | β | 2024 | β |
| Long-term night shift work, genetic predisposition and risk of incident asthma: a prospective cohort study. | Hu B et al. | β | 2024 | β |
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| Metabolic profiling reveals circulating biomarkers associated with incident and prevalent Parkinson's disease. | Hu W et al. | β | 2024 | β |
| Micronutrient intake and telomere length: findings from the UK Biobank. | Spinou M et al. | β | 2024 | β |
| Modifiable risk factors and excess mortality in depression: Data from the UK Biobank. | Boschesi Barros V et al. | β | 2024 | β |
| Multifaceted association of overweight and metabolically unhealthy with the risk of Barrett's esophagus in the UK Biobank cohort. | Jung DH et al. | β | 2024 | β |
| MuscleMap: An Open-Source, Community-Supported Consortium for Whole-Body Quantitative MRI of Muscle. | McKay MJ et al. | β | 2024 | β |
| Navigating Mendelian Randomization in Sleep Medicine: Challenges, Opportunities, and Best Practices. | BaHammam AS et al. | β | 2024 | β |
| Negative Emotions Are Associated With Older Self-perceived Age: A Cross-section Study From the UK Biobank. | Wang T et al. | β | 2024 | β |
| NHANES 2011-2014: Objective Physical Activity Is the Strongest Predictor of All-Cause Mortality. | Leroux A et al. | β | 2024 | β |
| Nongenetic and Genetic Factors Associated with White Matter Brain Aging: Exposome-Wide and Genome-Wide Association Study. | Feng L et al. | β | 2024 | β |
| Non-Linear Association of Dietary Polyamines with the Risk of Incident Dementia: Results from Population-Based Cohort of the UK Biobank. | Qian M et al. | β | 2024 | β |
| Nonlinear relationships of circulating polyunsaturated fatty acids with the complications of liver cirrhosis: A prospective, longitudinal cohort study. | Guo C et al. | β | 2024 | β |
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| Pervasive biases in proxy genome-wide association studies based on parental history of Alzheimer's disease. | Wu Y et al. | β | 2024 | β |
| PheMIME: an interactive web app and knowledge base for phenome-wide, multi-institutional multimorbidity analysis. | Zhang S et al. | β | 2024 | β |
| Pitfalls in interpreting calibration in comparative evaluations of risk models for precision lung cancer screening. | Brenner H et al. | β | 2024 | β |
| Plasma n6 polyunsaturated fatty acid levels and risk for total and cause-specific mortality: A prospective observational study from the UK Biobank. | Harris WS et al. | β | 2024 | β |
| Plasma proteomics and carotid intima-media thickness in the UK biobank cohort. | Chen ML et al. | β | 2024 | β |
| Polygenic risk and rare variant gene clustering enhance cancer risk stratification for breast and prostate cancers. | Kang JH et al. | β | 2024 | β |
| Polyunsaturated fatty acids and diabetic microvascular complications: a Mendelian randomization study. | Liu B et al. | β | 2024 | β |
| Population-Based Study of Rare Coding Variants in <i>NR5A1</i>/SF-1. | Kouri C et al. | β | 2024 | β |
| Prediagnostic Amino Acid Metabolites and Risk of Gout, Accounting for Serum Urate: Prospective Cohort Study and Mendelian Randomization. | McCormick N et al. | β | 2024 | β |
| Prequalification of genome-based newborn screening for severe childhood genetic diseases through federated training based on purifying hyperselection. | Kingsmore SF et al. | β | 2024 | β |
| Prevalence of Genetically Associated Dilated Cardiomyopathy: A Systematic Literature Review and Meta-Analysis. | Myers MC et al. | β | 2024 | β |
| Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation. | Carey CE et al. | β | 2024 | β |
| Prognostic Significance and Associations of Neural Network-Derived Electrocardiographic Features. | Sau A et al. | β | 2024 | β |
| Prospective Analysis of Circulating Biomarkers and Ovarian Cancer Risk in the UK Biobank. | Sasamoto N et al. | β | 2024 | β |
| Protein-truncating and rare missense variants in <i>ATM</i> and <i>CHEK2</i> and associations with cancer in UK Biobank whole-exome sequence data. | Mukhtar TK et al. | β | 2024 | β |
| Proteomic signatures improve risk prediction for common and rare diseases. | Carrasco-Zanini J et al. | β | 2024 | β |
| PWAS Hub for exploring gene-based associations of common complex diseases. | Kelman G et al. | β | 2024 | β |
| Rate of non-metastatic solid tumor progression following critical illness: a prospective cohort study of UK Biobank participants. | Puxty K et al. | β | 2024 | β |
| Real-world effectiveness of mepolizumab in patients with asthma and comorbid nasal polyps. | Ou MC et al. | β | 2024 | β |
| Refining the scope of genetic influences on alcohol misuse through environmental stratification and gene-environment interaction. | Savage JE et al. | β | 2024 | β |
| Regionally enriched rare deleterious exonic variants in the UK and Ireland. | Halachev M et al. | β | 2024 | β |
| Risk factors for raised left ventricular filling pressure by cardiovascular magnetic resonance: Prognostic insights. | Thomson RJ et al. | β | 2024 | β |
| Sex- and Substance-Specific Associations of Circadian-Related Genes with Addiction in the UK Biobank Cohort Implicate Neuroplasticity Pathways. | Khan A et al. | β | 2024 | β |
| Sex inequalities in cardiovascular risk prediction. | Elliott J et al. | β | 2024 | β |
| Sleep Irregularity and the Incidence of Type 2 Diabetes: A Device-Based Prospective Study in Adults. | Chaput JP et al. | β | 2024 | β |
| Sleep pattern, genetic risk, and the risk of incident rheumatoid arthritis: A cohort study. | Liu B et al. | β | 2024 | β |
| Sleep patterns, genetic susceptibility, and digestive diseases: a large-scale longitudinal cohort study. | Ma Y et al. | β | 2024 | β |
| Sociodemographic, health-related, and clinical characteristics and their associations with mortality among All of Us participants compared with the United States general population | Wang J et al. | β | 2024 | β |
| Socioeconomic inequalities, genetic susceptibility, and risks of depression and anxiety: A large-observational study. | Qi X et al. | β | 2024 | β |
| Socioeconomic Inequalities in Dementia Risk Among a Population-Based Cohort: Quantifying the Role of a Broad Combination of Lifestyle Factors. | Zhao Z et al. | β | 2024 | β |
| Sodium Intake and Atopic Dermatitis. | Chiang BM et al. | β | 2024 | β |
| Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes. | Gentreau M et al. | β | 2024 | β |
| Tea intake and non-alcoholic fatty liver disease risk: A two-sample Mendelian randomization study. | Lu C et al. | β | 2024 | β |
| Testing for a causal role of thyroid hormone measurements within the normal range on human metabolism and diseases: a systematic Mendelian randomization. | Alwan H et al. | β | 2024 | β |
| The Association of Dietary Polyamines with Mortality and the Risk of Cardiovascular Disease: A Prospective Study in UK Biobank. | Han S et al. | β | 2024 | β |
| The associations of n-3 fatty acid intake with handgrip strength and muscle mass indices in older adults: A cross-sectional study from UK Biobank. | Alsowail AT et al. | β | 2024 | β |
| The battle of the sexes in humans is highly polygenic. | Cole JM et al. | β | 2024 | β |
| The importance of family-based sampling for biobanks. | Davies NM et al. | β | 2024 | β |
| The pleiotropic spectrum of proximal 16p11.2 CNVs. | Auwerx C et al. | β | 2024 | β |
| The potential and translational application of infant genetic research. | Ronald A et al. | β | 2024 | β |
| The role of obesity in mortality from digestive diseases in UK Biobank. | Wang C et al. | β | 2024 | β |
| The urban desirability paradox: U.K. urban-rural differences in well-being, social satisfaction, and economic satisfaction. | Finnemann A et al. | β | 2024 | β |
| TM6SF2 -rs58542926 Genotype Has Opposing Effects on Incidence of Hepatic and Cardiac Events in a Community Cohort. | Chen VL et al. | β | 2024 | β |
| Unpicking Causal Relationships Between Grip Strength and Cardiorespiratory Fitness: A Bidirectional Mendelian Randomization Study. | Norris T et al. | β | 2024 | β |
| Using instruments for selection to adjust for selection bias in Mendelian randomization. | Gkatzionis A et al. | β | 2024 | β |
| Validation of the BOADICEA model for epithelial tubo-ovarian cancer risk prediction in UK Biobank. | Yang X et al. | β | 2024 | β |
| Visual Impairment, Eye Conditions, and Diagnoses of Neurodegeneration and Dementia. | Ferguson EL et al. | β | 2024 | β |
| Wildfire-related PM<sub>2.5</sub> and cause-specific cancer mortality. | Gao Y et al. | β | 2024 | β |