Auditory event-related potentials in children at high risk for alcoholism.
paper
Cited
Public
Unavailable
- Authors
- Steinhauer, S R; Hill, S Y
- Year
- 1993
- Journal
- Journal of studies on alcohol
- PMID
- 8341043
- DOI
- 10.15288/jsa.1993.54.408
To determine if P300 and other event-related potentials (ERP) could serve as markers for risk of developing alcoholism, two groups of children (8-18 years old) were tested. The high-risk (HR) group consisted of 51 children with an average of 4.1 first- and second-degree relatives who were alcoholic. The low-risk group (LR) consisted of 42 children who had no first- or second-degree relatives who were alcoholic or met criteria for DSM-III Axis I psychopathology. Auditory stimuli varying in conditional probability were presented during a silent counting task, and during a choice reaction task. P300 amplitude was smaller in high-risk than low-risk children. When grouped according to gender and developmental status (8-12 and 13-18 year olds), P300 showed the greatest reduction for the older high-risk males compared to low-risk males. In addition, a previous finding was replicated: the prolonged centro-frontal negativity (232-352 msec), which decreased with age in low-risk children, showed significantly less reduction for high-risk children. Risk status was not related to either amplitudes of the N100 and P200 components of the ERP, or to latencies of any components. Decreases in P300 amplitude and delayed reduction of anterior negativity appear related to developmental processes in high-risk children.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Epigenetic Effects in HPA Axis Genes Associated with Cortical Thickness, ERP Components and SUD Outcome. | Hill SY et al. | — | 2022 | → |
| P300 development from infancy to adolescence. | Riggins T et al. | — | 2020 | → |
| Longitudinal predictors of cannabis use and dependence in offspring from families at ultra high risk for alcohol dependence and in control families. | Hill SY et al. | — | 2016 | → |
| Longitudinal stability and predictive utility of the visual P3 response in adults with externalizing psychopathology. | Yoon HH et al. | — | 2015 | → |
| Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task. | Kamarajan C et al. | — | 2015 | → |
| Absence of P300 reduction in South African treatment-naïve adolescents with alcohol dependence. | Cuzen NL et al. | — | 2013 | → |
| Cholinergic receptor gene (CHRM2) variation and familial loading for alcohol dependence predict childhood developmental trajectories of P300. | Hill SY et al. | — | 2013 | → |
| The P300 event-related brain potential as a neurobiological endophenotype for substance use disorders: a meta-analytic investigation. | Euser AS et al. | — | 2012 | → |
| Event-related oscillations versus event-related potentials in a P300 task as biomarkers for alcoholism. | Andrew C et al. | — | 2010 | → |
| Neural plasticity, human genetics, and risk for alcohol dependence. | Hill SY | — | 2010 | → |
| Childhood risk factors for young adult substance dependence outcome in offspring from multiplex alcohol dependence families: a prospective study. | Hill SY et al. | — | 2009 | → |
| Chronic alcoholism: insights from neurophysiology. | Campanella S et al. | — | 2009 | → |
| The P300 event-related potential and its possible role as an endophenotype for studying substance use disorders: a review. | Singh SM et al. | — | 2009 | → |
| Deviant P300 amplitude development in males is associated with paternal externalizing psychopathology. | Carlson SR et al. | — | 2008 | → |
| Cerebellar volume in offspring from multiplex alcohol dependence families. | Hill SY et al. | — | 2007 | → |
| Delta and theta oscillations as risk markers in adolescent offspring of alcoholics. | Rangaswamy M et al. | — | 2007 | → |
| P3 components and adolescent binge drinking in Southwest California Indians. | Ehlers CL et al. | — | 2007 | → |
| S-transform time-frequency analysis of P300 reveals deficits in individuals diagnosed with alcoholism. | Jones KA et al. | — | 2006 | → |
| Using the brain P300 response to identify novel phenotypes reflecting genetic vulnerability for adolescent substance misuse. | Yoon HH et al. | — | 2006 | → |
| Neurodevelopmental patterns of visual P3b in association with familial risk for alcohol dependence and childhood diagnosis. | Hill SY et al. | — | 2002 | → |
| P300 amplitude in adolescent twins discordant and concordant for alcohol use disorders. | Carlson SR et al. | — | 2002 | → |
| Button-pressing affects P300 amplitude and scalp topography. | Salisbury DF et al. | — | 2001 | → |
| N1 and P300 abnormalities in patients with schizophrenia, epilepsy, and epilepsy with schizophrenialike features. | Ford JM et al. | — | 2001 | → |
| Visual P3 findings in Mission Indian youth: relationship to family history of alcohol dependence and behavioral problems. | Ehlers CL et al. | — | 2001 | → |
| Analysis of heritability of hormonal responses to alcohol in twins: beta-endorphin as a potential biomarker of genetic risk for alcoholism. | Froehlich JC et al. | — | 2000 | → |
| Biological phenotypes associated with individuals at high risk for developing alcohol-related disorders: Part 1. | Hill SY | — | 2000 | → |
| Factors predicting the onset of adolescent drinking in families at high risk for developing alcoholism. | Hill SY et al. | — | 2000 | → |
| Absence of visual and auditory P300 reduction in nondepressed male and female alcoholics. | Hill SY et al. | — | 1999 | → |
| Developmental delay in P300 production in children at high risk for developing alcohol-related disorders. | Hill SY et al. | — | 1999 | → |
| Path analysis of P300 amplitude of individuals from families at high and low risk for developing alcoholism. | Hill SY et al. | — | 1999 | → |
| Visual P3a in male subjects at high risk for alcoholism. | Rodríguez Holguín S et al. | — | 1999 | → |
| Alternative strategies for uncovering genes contributing to alcoholism risk: unpredictable findings in a genetic wonderland. | Hill SY | — | 1998 | → |
| Event-related potentials during visual selective attention in children of alcoholics. | van der Stelt O et al. | — | 1998 | → |
| Genetic association between reduced P300 amplitude and the DRD2 dopamine receptor A1 allele in children at high risk for alcoholism. | Hill SY et al. | — | 1998 | → |
| Mismatch negativity in young children of alcoholics from high-density families. | Rodríguez Holguín S et al. | — | 1998 | → |
| P3 scalp topography to target and novel visual stimuli in children of alcoholics. | Van der Stelt O et al. | — | 1998 | → |
| Visual and auditory event-related potentials in young children of alcoholics from high- and low-density families. | Rodríguez Holguín S et al. | — | 1998 | → |
| Alcohol, auditory functioning and deafness. | Crawford A | — | 1997 | → |
| Dipole source analysis of P300 component of the auditory evoked potential: a methodological advance? | Hegerl U et al. | — | 1997 | → |
| The D2 dopamine receptor (DRD2) gene and family stress; interactive effects on cognitive functions in children. | Berman SM et al. | — | 1997 | → |
| A simple auditory oddball task in young adult males at high risk for alcoholism. | Ramachandran G et al. | — | 1996 | → |
| EEG dimension in sons of alcoholics. | Ehlers CL et al. | — | 1995 | → |
| Eight-year longitudinal follow-up of P300 and clinical outcome in children from high-risk for alcoholism families. | Hill SY et al. | — | 1995 | → |
| Event-Related Potentials. | Hill SY | — | 1995 | → |
| Event-related potentials in alcoholic men, their high-risk male relatives, and low-risk male controls. | Hill SY et al. | — | 1995 | → |
| Exclusion of linkage between alcoholism and the MNS blood group region on chromosome 4q in multiplex families. | Neiswanger K et al. | — | 1995 | → |
| Neurobiological and Clinical Markers for a Severe Form of Alcoholism in Women. | Hill SY | — | 1995 | → |
| P300 amplitude decrements in children from families of alcoholic female probands. | Hill SY et al. | — | 1995 | → |
| Assessment of recovery of electrophysiological and neuropsychological functions in chronic alcoholics. | Glenn S et al. | — | 1994 | → |
| Children at risk for alcoholism. | Hill SY et al. | — | 1994 | → |
| Frontal P300 decrements in antisocial personality disorder. | Bauer LO et al. | — | 1994 | → |
| Postural sway in children from pedigrees exhibiting a high density of alcoholism. | Hill SY et al. | — | 1993 | → |