Five years of GWAS discovery.
paper
Cited
Public
Unavailable
- Authors
- Visscher, Peter M; Brown, Matthew A; McCarthy, Mark I; Yang, Jian
- Year
- 2012
- Journal
- American journal of human genetics
- PMID
- 22243964
- DOI
- 10.1016/j.ajhg.2011.11.029
- PMCID
- PMC3257326
The past five years have seen many scientific and biological discoveries made through the experimental design of genome-wide association studies (GWASs). These studies were aimed at detecting variants at genomic loci that are associated with complex traits in the population and, in particular, at detecting associations between common single-nucleotide polymorphisms (SNPs) and common diseases such as heart disease, diabetes, auto-immune diseases, and psychiatric disorders. We start by giving a number of quotes from scientists and journalists about perceived problems with GWASs. We will then briefly give the history of GWASs and focus on the discoveries made through this experimental design, what those discoveries tell us and do not tell us about the genetics and biology of complex traits, and what immediate utility has come out of these studies. Rather than giving an exhaustive review of all reported findings for all diseases and other complex traits, we focus on the results for auto-immune diseases and metabolic diseases. We return to the perceived failure or disappointment about GWASs in the concluding section.
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| Implementing Core Genes and an Omnigenic Model for Behaviour Traits Prediction in Genomics. | Rancelis T et al. | โ | 2023 | โ |
| Inferring the Genetic Influences on Psychological Traits Using MRI Connectivity Predictive Models: Demonstration with Cognition. | Hatoum AS et al. | โ | 2023 | โ |
| Innate and adaptive immune abnormalities underlying autoimmune diseases: the genetic connections. | Chi X et al. | โ | 2023 | โ |
| Integration of Mendelian randomisation and systems biology models to identify novel blood-based biomarkers for stroke. | Islam T et al. | โ | 2023 | โ |
| Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes. | Li J et al. | โ | 2023 | โ |
| Investigation of heteroscedasticity in polygenic risk scores across 15 quantitative traits. | Jung H et al. | โ | 2023 | โ |
| Joint Consideration of Means and Variances Might Change the Understanding of Etiology. | Burt SA et al. | โ | 2023 | โ |
| k-mer-based GWAS enhances the discovery of causal variants and candidate genes in soybean. | Lemay MA et al. | โ | 2023 | โ |
| Leveraging the genetic correlation between traits improves the detection of epistasis in genome-wide association studies. | Stamp J et al. | โ | 2023 | โ |
| <i>UNC13A</i> in amyotrophic lateral sclerosis: from genetic association to therapeutic target. | Willemse SW et al. | โ | 2023 | โ |
| Mendelian randomization analysis to elucidate the causal relationship between small molecule metabolites and ovarian cancer risk. | Chang X et al. | โ | 2023 | โ |
| metGWAS 1.0: an R workflow for network-driven over-representation analysis between independent metabolomic and meta-genome-wide association studies. | Khan SR et al. | โ | 2023 | โ |
| Moderation effects in personality disorder research. | Vize CE et al. | โ | 2023 | โ |
| mtPGS: Leverage multiple correlated traits for accurate polygenic score construction. | Xu C et al. | โ | 2023 | โ |
| multi-GPA-Tree: Statistical approach for pleiotropy informed and functional annotation tree guided prioritization of GWAS results. | Khatiwada A et al. | โ | 2023 | โ |
| Natural variation of respiration-related traits in plants. | Bulut M et al. | โ | 2023 | โ |
| New advances in CRISPR/Cas-mediated precise gene-editing techniques. | Richardson C et al. | โ | 2023 | โ |
| Pertinence of glioma and single nucleotide polymorphism of TERT, CCDC26, CDKN2A/B and RTEL1 genes in glioma: a meta-analysis. | Wu Y et al. | โ | 2023 | โ |
| Polygenic Risk Score for Cardiovascular Diseases in Artificial Intelligence Paradigm: A Review. | Khanna NN et al. | โ | 2023 | โ |
| Polygenic risk scores and breast cancer risk prediction. | Roberts E et al. | โ | 2023 | โ |
| Progress in genome-wide association studies of age at natural menopause. | Xu C et al. | โ | 2023 | โ |
| Publication trends of primary angle-closure disease during 1991-2022: a bibliometric analysis. | Huang HL et al. | โ | 2023 | โ |
| RETRACTED ARTICLE: The Association of Interleukin-16 Gene Polymorphisms with IL-16 Serum Levels and Risk of Multiple Sclerosis. | Farrokhi M et al. | โ | 2023 | โ |
| Review of mendelian randomization studies on age at natural menopause. | Zhang X et al. | โ | 2023 | โ |
| Sequencing technology as a major impetus in the advancement of studies into rheumatism: A bibliometric study. | Huang R et al. | โ | 2023 | โ |
| Simultaneous selection of multiple important single nucleotide polymorphisms in familial genome wide association studies data. | Majumdar S et al. | โ | 2023 | โ |
| Structural variants and short tandem repeats impact gene expression and splicing in bovine testis tissue. | Bhati M et al. | โ | 2023 | โ |
| SUMMER: a Mendelian randomization interactive serverย to systematically evaluate the causal effects of risk factors and circulating biomarkers on pan-cancer survival. | Xin J et al. | โ | 2023 | โ |
| The Causal Impact of the Gut Microbiota on Respiratory Tuberculosis Susceptibility. | Wen J et al. | โ | 2023 | โ |
| The clinical application of polygenic risk scores: Aย points to consider statement of the American College of Medical Genetics and Genomics (ACMG). | Abu-El-Haija A et al. | โ | 2023 | โ |
| The genetic basis of major depressive disorder. | Flint J | โ | 2023 | โ |
| The impact of entrepreneurship research on other academic fields. | Thurik AR et al. | โ | 2023 | โ |
| The role of the genome regulatory network in heart failure. | โ | โ | 2023 | โ |
| Transcriptome-wide gene-gene interaction associations elucidate pathways and functional enrichment of complex traits. | Evans LM et al. | โ | 2023 | โ |
| When the allergy alarm bells toll: The role of Toll-like receptors in allergic diseases and treatment. | Wenger M et al. | โ | 2023 | โ |
| Whole genome sequencing reveals population diversity and variation in HIV-1 specific host genes. | Thami PK et al. | โ | 2023 | โ |
| Why does the X chromosome lag behind autosomes in GWAS findings? | Gorlov IP et al. | โ | 2023 | โ |
| A Case-Control Study of the Association of Leptin Gene Polymorphisms with Plasma Leptin Levels and Obesity in the Kerala Population. | Manju SK et al. | โ | 2022 | โ |
| A computationally efficient clustering linear combination approach to jointly analyze multiple phenotypes for GWAS. | Wang M et al. | โ | 2022 | โ |
| A Genome-Wide Association Study and Machine-Learning Algorithm Analysis on the Prediction of Facial Phenotypes by Genotypes in Korean Women. | Yoo HY et al. | โ | 2022 | โ |
| A genome-wide association study of important reproduction traits in large white pigs. | Chang Wu Z et al. | โ | 2022 | โ |
| An adaptive combination method for Cauchy variable based on optimal threshold. | Tang Y et al. | โ | 2022 | โ |
| Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility. | Zou J et al. | โ | 2022 | โ |
| Analysis of Tryptophan and Its Main Metabolite Kynurenine and the Risk of Multiple Cancers Based on the Bidirectional Mendelian Randomization Analysis. | Li R et al. | โ | 2022 | โ |
| An implementation of a hybrid method based on machine learning to identify biomarkers in the Covid-19 diagnosis using DNA sequences. | Das B | โ | 2022 | โ |
| A Novel Approach to Link Genetics and Human MRI Identifies AKAP7-Dependent Subicular/Prefrontal Functional Connectivity as Altered in Suicidality. | Poblete G et al. | โ | 2022 | โ |
| An unbiased kinship estimation method for genetic data analysis. | Jiang W et al. | โ | 2022 | โ |
| Applying multi-omics techniques to the discovery of biomarkers for acute aortic dissection. | Hao X et al. | โ | 2022 | โ |
| Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. | Wainschtein P et al. | โ | 2022 | โ |
| Assessment of linkage disequilibrium patterns between structural variants and single nucleotide polymorphisms in three commercial chicken populations. | Geibel J et al. | โ | 2022 | โ |
| Associating complex traits with genetic variants: polygenic risk scores, pleiotropy and endophenotypes. | Fisch GS | โ | 2022 | โ |
| Associations Between Body Mass Index, WNT16 rs2908004 and Osteoporosis: Findings from Taiwan Biobank. | Wu CL et al. | โ | 2022 | โ |
| Average semivariance directly yields accurate estimates of the genomic variance in complex trait analyses. | Feldmann MJ et al. | โ | 2022 | โ |
| Bayesian Genetic Colocalization Test of Two Traits Using coloc. | Rasooly D et al. | โ | 2022 | โ |
| Bayesian mixed models for longitudinal genetic data: theory, concepts, and simulation studies. | Chung W et al. | โ | 2022 | โ |
| Categorical perception and influence of attention on neural consistency in response to speech sounds in adults with dyslexia. | Centanni TM et al. | โ | 2022 | โ |
| Combining GWAS, Genome-Wide Domestication and a Transcriptomic Analysis Reveals the Loci and Natural Alleles of Salt Tolerance in Rice (<i>Oryza sativa</i> L.). | Lv Y et al. | โ | 2022 | โ |
| Data Integration, Imputation, and Meta-analysis for Genome-Wide Association Studies. | Joukhadar R et al. | โ | 2022 | โ |
| DecodeME: community recruitment for a large genetics study of myalgic encephalomyelitis / chronic fatigue syndrome. | Devereux-Cooke A et al. | โ | 2022 | โ |
| Deconstructing a Syndrome: Genomic Insights Into PCOS Causal Mechanisms and Classification. | Dapas M et al. | โ | 2022 | โ |
| Development of a MAGIC population and high-resolution quantitative trait mapping for nicotine content in tobacco. | Yuan G et al. | โ | 2022 | โ |
| Diabetes mellitus susceptibility with varied diseased phenotypes and its comparison with phenome interactome networks. | Rout M et al. | โ | 2022 | โ |
| Digital Devices for Assessing Motor Functions in Mobility-Impaired and Healthy Populations: Systematic Literature Review. | Guo CC et al. | โ | 2022 | โ |
| Epidemiological characteristics and genetic alterations in adult diffuse glioma in East Asian populations. | Mo Z et al. | โ | 2022 | โ |
| Evidence that the pituitary gland connects type 2 diabetes mellitus and schizophrenia based on large-scale trans-ethnic genetic analyses. | Cai L et al. | โ | 2022 | โ |
| Exome-wide screening identifies novel rare risk variants for major depression disorder. | Cheng S et al. | โ | 2022 | โ |
| Extend mixed models to multilayer neural networks for genomic prediction including intermediate omics data. | Zhao T et al. | โ | 2022 | โ |
| Family history of obesity and the influence on physical activity and dietary adherence after bariatric surgery. | Fipps DC et al. | โ | 2022 | โ |
| Forward Genetics in Apicomplexa Biology: The Host Side of the Story. | Sรกnchez-Arcila JC et al. | โ | 2022 | โ |
| Functional genomics and the future of iPSCs in disease modeling. | Brooks IR et al. | โ | 2022 | โ |
| Genetic heterogeneity: Challenges, impacts, and methods through an associative lens. | Woodward AA et al. | โ | 2022 | โ |
| Genetics of irritable bowel syndrome: shifting gear via biobank-scale studies. | Camilleri M et al. | โ | 2022 | โ |
| Genome-wide association studies of preweaning growth and in vivo carcass composition traits in Esme sheep. | Yilmaz O et al. | โ | 2022 | โ |
| Genome-Wide Association Study and Genomic Prediction for Bacterial Wilt Resistance in Common Bean (<i>Phaseolus vulgaris</i>) Core Collection. | Zia B et al. | โ | 2022 | โ |
| Genome-Wide Association Study for Idiopathic Ventricular Tachyarrhythmias Identifies Key Role of <i>CCR7</i> and <i>PKN2</i> in Calcium Homeostasis and Cardiac Rhythm Maintenance. | Fang C et al. | โ | 2022 | โ |
| Genome wide association study of MAGIC population reveals a novel QTL for salinity and sodicity tolerance in rice. | Krishnamurthy SL et al. | โ | 2022 | โ |
| Genome-Wide Associative Study of Phenotypic Parameters of the 3D Body Model of Aberdeen Angus Cattle with Multiple Depth Cameras. | Ruchay A et al. | โ | 2022 | โ |
| GREEN-DB: a framework for the annotation and prioritization of non-coding regulatory variants from whole-genome sequencing data. | Giacopuzzi E et al. | โ | 2022 | โ |
| Hearing loss and tinnitus: association studies for complex-hearing disorders in mouse and man. | Boussaty EC et al. | โ | 2022 | โ |
| Host Genetic Determinants of the Microbiome Across Animals: From <i>Caenorhabditis elegans</i> to Cattle. | Ryu EP et al. | โ | 2022 | โ |
| Integrated analysis of proteome-wide and transcriptome-wide association studies identified novel genes and chemicals for vertigo. | Cheng B et al. | โ | 2022 | โ |
| Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations. | Breeze CE et al. | โ | 2022 | โ |
| Integrative analysis of multi-omics data to detect the underlying molecular mechanisms for obesity in vivo in humans. | Zhang Q et al. | โ | 2022 | โ |
| <i>PSRC1</i> May Affect Coronary Artery Disease Risk by Altering <i>CELSR2, PSRC1</i>, and <i>SORT1</i> Gene Expression and Circulating Granulin and Apolipoprotein B Protein Levels. | Chai T et al. | โ | 2022 | โ |
| Mapping the genetic architecture of cortical morphology through neuroimaging: progress and perspectives. | van der Meer D et al. | โ | 2022 | โ |
| Mendelian Randomization Analysis Identified Potential Genes Pleiotropically Associated with Polycystic Ovary Syndrome. | Sun Q et al. | โ | 2022 | โ |
| Metabolomics in Diabetic Retinopathy: From Potential Biomarkers to Molecular Basis of Oxidative Stress. | Jian Q et al. | โ | 2022 | โ |
| Metagenomics and chemotherapy-induced nausea: A roadmap for future research. | Crowder SL et al. | โ | 2022 | โ |
| MoNET: an R package for multi-omic network analysis. | Li J et al. | โ | 2022 | โ |
| New insights into genetics underlying of plumage color. | Davoodi P et al. | โ | 2022 | โ |
| Obesity and Adipose Tissue-derived Cytokines in the Pathogenesis of Multiple Sclerosis. | Daryabor G et al. | โ | 2022 | โ |
| Open problems in human trait genetics. | Brandes N et al. | โ | 2022 | โ |
| Optimizing sampling design and sequencing strategy for the genomic analysis of quantitative traits in natural populations. | Paril JF et al. | โ | 2022 | โ |
| Polycystic Ovary Syndrome: An Evolutionary Adaptation to Lifestyle and the Environment. | Parker J et al. | โ | 2022 | โ |
| Polygenic power calculator: Statistical power and polygenic prediction accuracy of genome-wide association studies of complex traits. | Wu T et al. | โ | 2022 | โ |
| Prediabetes blunts DPP4 genetic control of postprandial glycaemia and insulin secretion. | Patarrรฃo RS et al. | โ | 2022 | โ |
| Predicting Physical Appearance from DNA Data-Towards Genomic Solutions. | Poลpiech E et al. | โ | 2022 | โ |
| Review of Mendelian Randomization Studies on Endometrial Cancer. | Guo JZ et al. | โ | 2022 | โ |
| Simultaneous Detection of Signal Regions Using Quadratic Scan Statistics With Applications to Whole Genome Association Studies. | Li Z et al. | โ | 2022 | โ |
| SNP-based heritability and selection analyses: Improved models and new results. | Speed D et al. | โ | 2022 | โ |
| SNP characteristics and validation success in genome wide association studies. | Gorlova OY et al. | โ | 2022 | โ |
| sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies. | Nasirigerdeh R et al. | โ | 2022 | โ |
| Statistical methods for Mendelian randomization in genome-wide association studies: A review. | Boehm FJ et al. | โ | 2022 | โ |
| Strengthening Causal Inference in Exposomics Research: Application of Genetic Data and Methods. | Avery CL et al. | โ | 2022 | โ |
| Systematic Review: Molecular Studies of Common Genetic Variation in Child and Adolescent Psychiatric Disorders. | Akingbuwa WA et al. | โ | 2022 | โ |
| 'Teratoid' Hepatoblastoma: An Intriguing Variant of Mixed Epithelial-Mesenchymal Hepatoblastoma. | Sergi CM et al. | โ | 2022 | โ |
| The Candidate Chromosomal Regions Responsible for Milk Yield of Cow: A GWAS Meta-Analysis. | Taherkhani L et al. | โ | 2022 | โ |
| The effect of heteroscedasticity on the prediction efficiency of genome-wide polygenic score for body mass index. | Baek EJ et al. | โ | 2022 | โ |
| The effect of polygenic risk scores for major depressive disorder, bipolar disorder and schizophrenia on morphological brain measures: A systematic review of the evidence. | Cattarinussi G et al. | โ | 2022 | โ |
| The missing diversity in human epigenomic studies. | Breeze CE et al. | โ | 2022 | โ |
| Transcriptomic analysis provides insights into molecular mechanisms of thermal physiology. | Drown MK et al. | โ | 2022 | โ |
| TSABL: Trait Specific Annotation Based Locus predictor. | Lorenz K et al. | โ | 2022 | โ |
| Using Polygenic Risk Scores Related to Complex Traits to Predict Production Performance in Cross-Breeding of Yeast. | Dai Y et al. | โ | 2022 | โ |
| Whole Exome Sequencing Study Identifies Novel Rare Risk Variants for Habitual Coffee Consumption Involved in Olfactory Receptor and Hyperphagia. | Cheng B et al. | โ | 2022 | โ |
| Accelerated deciphering of the genetic architecture of agricultural economic traits in pigs using a low-coverage whole-genome sequencing strategy. | Yang R et al. | โ | 2021 | โ |
| Accounting for Population Structure and Phenotypes From Relatives in Association Mapping for Farm Animals: A Simulation Study. | Mancin E et al. | โ | 2021 | โ |
| Advances and challenges in quantitative delineation of the genetic architecture of complex traits. | Tang H et al. | โ | 2021 | โ |
| An efficient linear mixed model framework for meta-analytic association studies across multiple contexts. | Jew B et al. | โ | 2021 | โ |
| An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci. | Mountjoy E et al. | โ | 2021 | โ |
| Applications and Challenges of Machine Learning Methods in Alzheimer's Disease Multi-Source Data Analysis. | Li X et al. | โ | 2021 | โ |
| Approach to genetic diagnosis of inborn errors of immunity through next-generation sequencing. | Karimi E et al. | โ | 2021 | โ |
| A prototypical conceptualization of mechanisms. | Cunningham B | โ | 2021 | โ |
| ARRDC4 and UBXN1: Novel Target Genes Correlated with Prostate Cancer Gleason Score. | Oh JJ et al. | โ | 2021 | โ |
| Assessing Genetic Overlap and Causality Between Blood Plasma Proteins and Alzheimer's Disease. | Handy A et al. | โ | 2021 | โ |
| A survival of the fittest strategy for the selection of genotypes by which drug responders and non-responders can be predicted in small groups. | Hรถhle D et al. | โ | 2021 | โ |
| A two-stage testing strategy for detecting genesรenvironment interactions in association studies. | Zhou J et al. | โ | 2021 | โ |
| Average semivariance yields accurate estimates of the fraction of marker-associated genetic variance and heritability in complex trait analyses. | Feldmann MJ et al. | โ | 2021 | โ |
| Bibliometric Insights in Genetic Factors of Substance-Related Disorders: Intellectual Developments, Turning Points, and Emerging Trends. | Wang K et al. | โ | 2021 | โ |
| BTOB: Extending the Biased GWAS to Bivariate GWAS. | Zhu J et al. | โ | 2021 | โ |
| Cold-Blooded and on Purpose: A Review of the Biology of Proactive Aggression. | Belfry KD et al. | โ | 2021 | โ |
| Conceptualization of population-specific human functional immune-genomics projects to identify factors that contribute to variability in immune and infectious diseases. | Boahen CK et al. | โ | 2021 | โ |
| Congenital heart disease risk loci identified by genome-wide association study in European patients. | Lahm H et al. | โ | 2021 | โ |
| Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances. | Monnot S et al. | โ | 2021 | โ |
| DeepCOMBI: explainable artificial intelligence for the analysis and discovery in genome-wide association studies. | Mieth B et al. | โ | 2021 | โ |
| Detection of breeding signatures in wheat using a linkage disequilibrium-corrected mapping approach. | Dadshani S et al. | โ | 2021 | โ |
| Diagnosis and treatment of type 1 diabetes at the dawn of the personalized medicine era. | Akil AA et al. | โ | 2021 | โ |
| Differential Effect of Polymorphisms on Body Mass Index Across the Life Course of Japanese: The Japan Multi-Institutional Collaborative Cohort Study. | Iwase M et al. | โ | 2021 | โ |
| Dissecting polygenic signals from genome-wide association studies on human behaviour. | Abdellaoui A et al. | โ | 2021 | โ |
| Distinguishing HapMap Accessions Through Recursive Set Partitioning in Hierarchical Decision Trees. | Zhang W et al. | โ | 2021 | โ |
| Dynamic CTCF binding directly mediates interactions among cis-regulatory elements essential for hematopoiesis. | Qi Q et al. | โ | 2021 | โ |
| Gene Hunting Approaches through the Combination of Linkage Analysis with Whole-Exome Sequencing in Mendelian Diseases: From Darwin to the Present Day. | Susgun S et al. | โ | 2021 | โ |
| Genetic Architecture of Depression: Where Do We Stand Now? | Unal-Aydin P et al. | โ | 2021 | โ |
| Genetic association research in football: A systematic review. | McAuley ABT et al. | โ | 2021 | โ |
| Genetic Epidemiology of Complex Phenotypes. | O'Rielly DD et al. | โ | 2021 | โ |
| Genetic interactions effects for cancer disease identification using computational models: a review. | Manavalan R et al. | โ | 2021 | โ |
| Genetic interactions with stressful environments in depression and addiction. | Burmeister M et al. | โ | 2021 | โ |
| Genetic Polymorphism of Vitamin D Family Genes <i>CYP2R1</i>, <i>CYP24A1</i>, and <i>CYP27B1</i> Are Associated With a High Risk of Non-alcoholic Fatty Liver Disease: A Case-Control Study. | Wang M et al. | โ | 2021 | โ |
| Genetic prediction of complex traits with polygenic scores: a statistical review. | Ma Y et al. | โ | 2021 | โ |
| Genetic variants related to physical activity or sedentary behaviour: a systematic review. | Aasdahl L et al. | โ | 2021 | โ |
| Genome-wide association mapping in maize: status and prospects. | Shikha K et al. | โ | 2021 | โ |
| Genome-wide association studies: assessing trait characteristics in model and crop plants. | Alseekh S et al. | โ | 2021 | โ |
| Genomic analysis of ionome-related QTLs in Arabidopsis thaliana. | Shariatipour N et al. | โ | 2021 | โ |
| Gut microbiota is associated with bone mineral density : an observational and genome-wide environmental interaction analysis in the UK Biobank cohort. | Cheng B et al. | โ | 2021 | โ |
| GWAS-Based Discoveries in IgA Nephropathy, Membranous Nephropathy, and Steroid-Sensitive Nephrotic Syndrome. | Sanchez-Rodriguez E et al. | โ | 2021 | โ |
| GxEsum: a novel approach to estimate the phenotypic variance explained by genome-wide GxE interaction based on GWAS summary statistics for biobank-scale data. | Shin J et al. | โ | 2021 | โ |
| Identification of Germline Genetic Variants that Increase Prostate Cancer Risk and Influence Development of Aggressive Disease. | Saunders EJ et al. | โ | 2021 | โ |
| Impaired Reproductive Function in Equines: From Genetics to Genomics. | Laseca N et al. | โ | 2021 | โ |
| Improving reporting standards for polygenic scores in risk prediction studies. | Wand H et al. | โ | 2021 | โ |
| Influence of the kappa casein genotype on the technological properties of cow milk of Simmental and Alatau breeds. | Khastayeva AZ et al. | โ | 2021 | โ |
| Interpretable artificial neural networks incorporating Bayesian alphabet models for genome-wide prediction and association studies. | Zhao T et al. | โ | 2021 | โ |
| Low-pass sequencing increases the power of GWAS and decreases measurement error of polygenic risk scores compared to genotyping arrays. | Li JH et al. | โ | 2021 | โ |
| Machine Learning Identifies Six Genetic Variants and Alterations in the Heart Atrial Appendage as Key Contributors to PD Risk Predictivity. | Ho D et al. | โ | 2021 | โ |
| Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder. | Yang H et al. | โ | 2021 | โ |
| Meta-Analysis of Transcriptome-Wide Association Studies across 13 Brain Tissues Identified Novel Clusters of Genes Associated with Nicotine Addiction. | Ye Z et al. | โ | 2021 | โ |
| Multiparental Population in Crops: Methods of Development and Dissection of Genetic Traits. | Diouf I et al. | โ | 2021 | โ |
| Multi-scale inference of genetic trait architecture using biologically annotated neural networks. | Demetci P et al. | โ | 2021 | โ |
| Multi-tissue transcriptome-wide association studies. | Grinberg NF et al. | โ | 2021 | โ |
| Multi-Trait Genomic Risk Stratification for Type 2 Diabetes. | Rohde PD et al. | โ | 2021 | โ |
| Network-guided search for genetic heterogeneity between gene pairs. | Gumpinger AC et al. | โ | 2021 | โ |
| Phenotype risk scores (PheRS) for pancreatic cancer using time-stamped electronic health record data: Discovery and validation in two large biobanks. | Salvatore M et al. | โ | 2021 | โ |
| Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases. | Yu Z et al. | โ | 2021 | โ |
| Population genetic considerations for using biobanks as international resources in the pandemic era and beyond. | Carress H et al. | โ | 2021 | โ |
| Protocol for Construction of Genome-Wide Epistatic SNP Networks Using WISH-R Package. | Kadarmideen HN et al. | โ | 2021 | โ |
| Putting Psychology to the Test: Rethinking Model Evaluation Through Benchmarking and Prediction. | Rocca R et al. | โ | 2021 | โ |
| Rare Coding Variants Associated with Breast Cancer. | Han MR | โ | 2021 | โ |
| Recessive/dominant model: Alternative choice in case-control-based genome-wide association studies. | Liu HM et al. | โ | 2021 | โ |
| Relationship between Expression of Plasma lncRNA-HEIH and Prognosis in Patients with Coronary Artery Disease. | Zhang Z et al. | โ | 2021 | โ |
| Resisting Potato Cyst Nematodes With Resistance. | Gartner U et al. | โ | 2021 | โ |
| Response and Toxicity to Cytarabine Therapy in Leukemia and Lymphoma: From Dose Puzzle to Pharmacogenomic Biomarkers. | Di Francia R et al. | โ | 2021 | โ |
| Semi-parametric empirical Bayes factor for genome-wide association studies. | Morisawa J et al. | โ | 2021 | โ |
| Sleep deficits and cannabis use behaviors: an analysis of shared genetics using linkage disequilibrium score regression and polygenic risk prediction. | Winiger EA et al. | โ | 2021 | โ |
| Some comments on using of Web of Science Core Collection for bibliometric studies in <i>Ann Transl Med</i>. Vol. 8. | Ho YS | โ | 2021 | โ |
| Sperm DNA methylation epimutation biomarker for paternal offspring autism susceptibility. | Garrido N et al. | โ | 2021 | โ |
| Statistical models and computational tools for predicting complex traits and diseases. | Chung W | โ | 2021 | โ |
| Status and prospects of genome-wide association studies in plants. | Tibbs Cortes L et al. | โ | 2021 | โ |
| The EpiDiverse Plant Epigenome-Wide Association Studies (EWAS) Pipeline. | Can SN et al. | โ | 2021 | โ |
| The evolution of group differences in changing environments. | Harpak A et al. | โ | 2021 | โ |
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| The relationship between body mass index and income: Using genetic variants from HUNT as instrumental variables. | Edwards CH et al. | โ | 2021 | โ |
| The Role of Electronic Health Records in Advancing Genomic Medicine. | Linder JE et al. | โ | 2021 | โ |
| Transcriptome prediction performance across machine learning models and diverse ancestries. | Okoro PC et al. | โ | 2021 | โ |
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| Ultra Low-Coverage Whole-Genome Sequencing as an Alternative to Genotyping Arrays in Genome-Wide Association Studies. | Chat V et al. | โ | 2021 | โ |
| Using "-omics" Data to Inform Genome-wide Association Studies (GWASs) in the Osteoporosis Field. | Abood A et al. | โ | 2021 | โ |
| Accurate and Scalable Construction of Polygenic Scores in Large Biobank Data Sets. | Yang S et al. | โ | 2020 | โ |
| Additional common loci associated with stroke and obesity identified using pleiotropic analytical approach. | Wang L et al. | โ | 2020 | โ |
| Age-dependent regional retinal nerve fibre changes in SIX1/SIX6 polymorphism. | Charng J et al. | โ | 2020 | โ |
| Allele-specific genome targeting in the development of precision medicine. | Wu J et al. | โ | 2020 | โ |
| A Method to Stop Analyzing Random Error and Start Analyzing Differential Responders to Exercise. | Dankel SJ et al. | โ | 2020 | โ |
| A Multiple-Trait Bayesian Lasso for Genome-Enabled Analysis and Prediction of Complex Traits. | Gianola D et al. | โ | 2020 | โ |
| A Multi-tissue Transcriptome Analysis of Human Metabolites Guides Interpretability of Associations Based on Multi-SNP Models for Gene Expression. | Ndungu A et al. | โ | 2020 | โ |
| ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing. | Fan J et al. | โ | 2020 | โ |
| Assessing differential responders and mean changes in muscle size, strength, and the crossover effect to 2 distinct resistance training protocols. | Dankel SJ et al. | โ | 2020 | โ |
| Association Between <i>FoxO1</i>, <i>A2M</i>, and <i>TGF-ฮฒ1</i>, Environmental Factors, and Major Depressive Disorder. | Zhao M et al. | โ | 2020 | โ |
| Association of a genetic risk score with BMI along the life-cycle: Evidence from several US cohorts. | Sanz-de-Galdeano A et al. | โ | 2020 | โ |
| Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data. | Howey R et al. | โ | 2020 | โ |
| Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model. | Holland D et al. | โ | 2020 | โ |
| Biomarker development for axial spondyloarthritis. | Brown MA et al. | โ | 2020 | โ |
| Broad consent under the GDPR: an optimistic perspective on a bright future. | Hallinan D | โ | 2020 | โ |
| Channels to consciousness: a possible role of gap junctions in consciousness. | Dere D et al. | โ | 2020 | โ |
| Cognitive ability and education: How behavioural genetic research has advanced our knowledge and understanding of their association. | Malanchini M et al. | โ | 2020 | โ |
| Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle. | Fang L et al. | โ | 2020 | โ |
| COVID-19 outcomes and the human genome. | Murray MF et al. | โ | 2020 | โ |
| CUBIC: an atlas of genetic architecture promises directed maize improvement. | Liu HJ et al. | โ | 2020 | โ |
| Deploying Big Data to Crack the Genotype to Phenotype Code. | Westerman EL et al. | โ | 2020 | โ |
| Effects of the Openness to Experience Polygenic Score on Cortical Thickness and Functional Connectivity. | Ren Z et al. | โ | 2020 | โ |
| Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of complex traits in cattle and human. | Liu S et al. | โ | 2020 | โ |
| Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traits. | Cheng W et al. | โ | 2020 | โ |
| Evaluation of population stratification adjustment using genome-wide or exonic variants. | Chen Y et al. | โ | 2020 | โ |
| Exploring how Family and Neighborhood Stressors Influence Genetic Risk for Adolescent Conduct Problems and Alcohol Use. | Bares CB et al. | โ | 2020 | โ |
| Extending long-range phasing and haplotype library imputation algorithms to large and heterogeneous datasets. | Money D et al. | โ | 2020 | โ |
| GEN2VCF: a converter for human genome imputation output format to VCF format. | Shin DM et al. | โ | 2020 | โ |
| Gene expression networks in the <i>Drosophila</i> Genetic Reference Panel. | Everett LJ et al. | โ | 2020 | โ |
| General regression model: A "model-free" association test for quantitative traits allowing to test for the underlying genetic model. | Gloaguen E et al. | โ | 2020 | โ |
| Genetic Risk Factors and Disease Modifiers of Nonalcoholic Steatohepatitis. | Kozlitina J | โ | 2020 | โ |
| Genetics of rheumatic fever and rheumatic heart disease. | Muhamed B et al. | โ | 2020 | โ |
| Genetic Variant Set-Based Tests Using the Generalized Berk-Jones Statistic with Application to a Genome-Wide Association Study of Breast Cancer. | Sun R et al. | โ | 2020 | โ |
| Genome Wide Analysis for Growth at Two Growth Stages in A New Fast-Growing Common Carp Strain (Cyprinus carpio L.). | Su S et al. | โ | 2020 | โ |
| Genome-wide association studies of cardiac electrical phenotypes. | Glinge C et al. | โ | 2020 | โ |
| Genome-wide association study of shared liability to anxiety disorders in Army STARRS. | Hettema JM et al. | โ | 2020 | โ |
| Genome-wide association study of the TP53 R249S mutation in hepatocellular carcinoma with aflatoxin B1 exposure and infection with hepatitis B virus. | Han C et al. | โ | 2020 | โ |
| Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort. | Osborne AJ et al. | โ | 2020 | โ |
| Genome-wide heritability analysis of severe malaria resistance reveals evidence of polygenic inheritance. | Damena D et al. | โ | 2020 | โ |
| Genome-wide pathogenesis interpretation using a heat diffusion-based systems genetics method and implications for gene function annotation. | Quan Y et al. | โ | 2020 | โ |
| Genomic Study of <i>Babesia bovis</i> Infection Level and Its Association With Tick Count in Hereford and Braford Cattle. | Cavani L et al. | โ | 2020 | โ |
| Goat DNMT3B: An indel mutation detection, association analysis with litter size and mRNA expression in gonads. | Hui Y et al. | โ | 2020 | โ |
| Heritability and genome-wide association of swine gut microbiome features with growth and fatness parameters. | Bergamaschi M et al. | โ | 2020 | โ |
| Identification and analysis of 35 genes associated with vitamin D deficiency: A systematic review to identify genetic variants. | Sepulveda-Villegas M et al. | โ | 2020 | โ |
| Identification of functionally connected multi-omic biomarkers for Alzheimer's disease using modularity-constrained Lasso. | Xie L et al. | โ | 2020 | โ |
| Identification of nodulation-related genes in <i>Medicago truncatula</i> using genome-wide association studies and co-expression networks. | Michno JM et al. | โ | 2020 | โ |
| Identification of novel variants and candidate genes associated with porcine bone mineral density using genome-wide association study. | Nan JH et al. | โ | 2020 | โ |
| Identifying rare variants for quantitative traits in extreme samples of population via Kullback-Leibler distance. | Xiang Y et al. | โ | 2020 | โ |
| Integrating germline and somatic genetics to identify genes associated with lung cancer. | Pattee J et al. | โ | 2020 | โ |
| Integrating transcriptome-wide association study and copy number variation study identifies candidate genes and pathways for diffuse non-Hodgkin's lymphoma. | Wu D et al. | โ | 2020 | โ |
| Integration of SNP Disease Association, eQTL, and Enrichment Analyses to Identify Risk SNPs and Susceptibility Genes in Chronic Obstructive Pulmonary Disease. | Liu Y et al. | โ | 2020 | โ |
| Integrative analysis highlighted susceptibility genes for rheumatoid arthritis. | Mo XB et al. | โ | 2020 | โ |
| Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies. | Ainsworth HC et al. | โ | 2020 | โ |
| Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data. | Shi H et al. | โ | 2020 | โ |
| Massively parallel techniques for cataloguing the regulome of the human brain. | Townsley KG et al. | โ | 2020 | โ |
| Mendelian Randomization analysis of the causal effect of adiposity on hospital costs. | Dixon P et al. | โ | 2020 | โ |
| Mendelian randomization analysis revealed potential causal factors for systemic lupus erythematosus. | Mo X et al. | โ | 2020 | โ |
| Mito-Omics and immune function: Applying novel mitochondrial omic techniques to the context of the aging immune system. | Silverstein AR et al. | โ | 2020 | โ |
| Neurogenetic and Neuroepigenetic Mechanisms in Cognitive Health and Disease. | Coda DM et al. | โ | 2020 | โ |
| Next Generation Sequencing and Bioinformatics Analysis of Family Genetic Inheritance. | Kanzi AM et al. | โ | 2020 | โ |
| Obesity Genomics and Metabolomics: a Nexus of Cardiometabolic Risk. | Regan JA et al. | โ | 2020 | โ |
| OPENMENDEL: a cooperative programming project for statistical genetics. | Zhou H et al. | โ | 2020 | โ |
| Opinion: Is gene mapping in wild populations useful for understanding and predicting adaptation to global change? | Gienapp P | โ | 2020 | โ |
| Physical activity in early adolescence predicts depressive symptoms 3 years later: A community-based study. | Isaksson J et al. | โ | 2020 | โ |
| Psychotic-like experiences during early adolescence predict symptoms of depression, anxiety, and conduct problems three years later: A community-based study. | Isaksson J et al. | โ | 2020 | โ |
| PWAS: proteome-wide association study-linking genes and phenotypes by functional variation in proteins. | Brandes N et al. | โ | 2020 | โ |
| Rare genetic variants in systemic autoimmunity. | Jiang SH et al. | โ | 2020 | โ |
| Reverse-genetics studies of lncRNAs-what we have learnt and paths forward. | Gao F et al. | โ | 2020 | โ |
| Sequence Variants Linked to Key Traits in Interspecific Crosses between African and Asian Rice. | Badro H et al. | โ | 2020 | โ |
| Shared molecular genetic risk of alcohol dependence and posttraumatic stress disorder (PTSD). | Sheerin CM et al. | โ | 2020 | โ |
| The contribution of rare genetic variants to the pathogenesis of polycystic ovary syndrome. | Dapas M et al. | โ | 2020 | โ |
| The Dawn of the Age of Multi-Parent MAGIC Populations in Plant Breeding: Novel Powerful Next-Generation Resources for Genetic Analysis and Selection of Recombinant Elite Material. | Arrones A et al. | โ | 2020 | โ |
| The emergent phenomenon of aspirin resistance: insights from genetic association studies. | Ferreira M et al. | โ | 2020 | โ |
| The Genetic Architecture of High Bone Mass. | Gregson CL et al. | โ | 2020 | โ |
| The genetic etiology of eosinophilic esophagitis. | Kottyan LC et al. | โ | 2020 | โ |
| The Relative Contributions of Socioeconomic and Genetic Factors to Variations in Body Mass Index Among Young Adults. | Kim R et al. | โ | 2020 | โ |
| The Role of Genetics in Cardiovascular Risk Reduction: Findings From a Single Lipid Clinic and Review of the Literature. | Benes LB et al. | โ | 2020 | โ |
| The rs4759314 SNP within Hotair lncRNA is associated with risk of multiple sclerosis. | Taheri M et al. | โ | 2020 | โ |
| The social and genetic inheritance of educational attainment: Genes, parental education, and educational expansion. | Lin MJ | โ | 2020 | โ |
| Unravelling the complex genetics of common kidney diseases: from variants to mechanisms. | Sullivan KM et al. | โ | 2020 | โ |
| Using genetics for social science. | Harden KP et al. | โ | 2020 | โ |
| Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture. | Hou K et al. | โ | 2019 | โ |
| ADGRL3 (LPHN3) variants predict substance use disorder. | Arcos-Burgos M et al. | โ | 2019 | โ |
| A genome-wide association study on photic sneeze reflex in the Chinese population. | Wang M et al. | โ | 2019 | โ |
| An evaluation of noncoding genome annotation tools through enrichment analysis of 15 genome-wide association studies. | Li B et al. | โ | 2019 | โ |
| A Positive Causal Influence of IL-18 Levels on the Risk of T2DM: A Mendelian Randomization Study. | Zhuang H et al. | โ | 2019 | โ |
| A preliminary investigation of rare variants associated with genetic risk for PTSD in a natural disaster-exposed adolescent sample. | Sheerin CM et al. | โ | 2019 | โ |
| A scientometric review of genome-wide association studies. | Mills MC et al. | โ | 2019 | โ |
| Assessing the genetic diversity and characterizing genomic regions conferring Tan Spot resistance in cultivated rye. | Sidhu JS et al. | โ | 2019 | โ |
| Assessing the performance of genome-wide association studies for predicting disease risk. | Patron J et al. | โ | 2019 | โ |
| Atrial Fibrillation Genetics Update: Toward Clinical Implementation. | Kalstรธ SM et al. | โ | 2019 | โ |
| Bayesian meta-analysis across genome-wide association studies of diverse phenotypes. | Trochet H et al. | โ | 2019 | โ |
| Benefits and limitations of genome-wide association studies. | Tam V et al. | โ | 2019 | โ |
| Characterizing rare and low-frequency height-associated variants in the Japanese population. | Akiyama M et al. | โ | 2019 | โ |
| Chromosome-based gene co-expression analysis reveals regions associated with cancers: chromosome 1 as an example. | Liu W | โ | 2019 | โ |
| Current Affairs of Microbial Genome-Wide Association Studies: Approaches, Bottlenecks and Analytical Pitfalls. | San JE et al. | โ | 2019 | โ |
| Data Integration in Poplar: 'Omics Layers and Integration Strategies. | Weighill D et al. | โ | 2019 | โ |
| Development and evaluation of a transfusion medicine genome wide genotyping array. | Guo Y et al. | โ | 2019 | โ |
| Discovery of rare variants implicated in schizophrenia using next-generation sequencing. | Rhoades R et al. | โ | 2019 | โ |
| Diversity In Precision Medicine And Pharmacogenetics: Methodological And Conceptual Considerations For Broadening Participation. | Popejoy AB | โ | 2019 | โ |
| Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole-Genome Sequencing Studies. | Li Z et al. | โ | 2019 | โ |
| EnDisease: a manually curated database for enhancer-disease associations. | Zeng W et al. | โ | 2019 | โ |
| Established and emerging strategies to crack the genetic code of obesity. | Tam V et al. | โ | 2019 | โ |
| EWASdb: epigenome-wide association study database. | Liu D et al. | โ | 2019 | โ |
| ForestQC: Quality control on genetic variants from next-generation sequencing data using random forest. | Li J et al. | โ | 2019 | โ |
| From Genotype to Phenotype: Through Chromatin. | Romanowska J et al. | โ | 2019 | โ |
| From R.A. Fisher's 1918 Paper to GWAS a Century Later. | Visscher PM et al. | โ | 2019 | โ |
| GARFIELD classifies disease-relevant genomic features through integration of functional annotations with association signals. | Iotchkova V et al. | โ | 2019 | โ |
| Generalized Structured Component Analysis in candidate gene association studies: applications and limitations. | Thompson PA et al. | โ | 2019 | โ |
| Genes in immune pathways associated with abnormal white matter integrity in first-episode and treatment-naรฏve patients with schizophrenia. | Xiang B et al. | โ | 2019 | โ |
| Genetic Contributions to Loneliness and Their Relevance to the Evolutionary Theory of Loneliness. | Spithoven AWM et al. | โ | 2019 | โ |
| Genetic risk for coronary heart disease alters the influence of Alzheimer's genetic risk on mild cognitive impairment. | Elman JA et al. | โ | 2019 | โ |
| Genetics and the geography of health, behaviour and attainment. | Belsky DW et al. | โ | 2019 | โ |
| Genetics of clozapine-associated neutropenia: recent advances, challenges and future perspective. | Legge SE et al. | โ | 2019 | โ |
| Genetic Studies of Tic Disorders and Tourette Syndrome. | Qi Y et al. | โ | 2019 | โ |
| Genetic Susceptibility, Dietary Protein Intake, and Changes of Blood Pressure: The POUNDS Lost Trial. | Sun D et al. | โ | 2019 | โ |
| Genome-Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education. | Donati G et al. | โ | 2019 | โ |
| Genomic architecture of complex traits in loblolly pine. | De La Torre AR et al. | โ | 2019 | โ |
| Genomic changes in the biological control agent <i>Cryptolaemus montrouzieri</i> associated with introduction. | Li HS et al. | โ | 2019 | โ |
| GWAS of Behavioral Traits. | Mehta D et al. | โ | 2019 | โ |
| Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology. | Taylor DL et al. | โ | 2019 | โ |
| How genome-wide association studies (GWAS) made traditional candidate gene studies obsolete. | Duncan LE et al. | โ | 2019 | โ |
| How the diversity of the faces arises. | Wu Z et al. | โ | 2019 | โ |
| <i>De novo</i> Mutations From Whole Exome Sequencing in Neurodevelopmental and Psychiatric Disorders: From Discovery to Application. | Wang W et al. | โ | 2019 | โ |
| Identifying genetic determinants of complex phenotypes from whole genome sequence data. | Long GS et al. | โ | 2019 | โ |
| Influence of obesity, parental history of diabetes, and genes in type 2 diabetes: A case-control study. | Berumen J et al. | โ | 2019 | โ |
| Integrative Analysis of Transcriptome and GWAS Data to Identify the Hub Genes Associated With Milk Yield Trait in Buffalo. | Deng T et al. | โ | 2019 | โ |
| Integrative analysis revealed potential causal genetic and epigenetic factors for multiple sclerosis. | Mo XB et al. | โ | 2019 | โ |
| Integrative omics analysis identifies macrophage migration inhibitory factor signaling pathways underlying human hepatic fibrogenesis and fibrosis. | Liu Z et al. | โ | 2019 | โ |
| Investigation of the association between obesity and insulin-induced gene 1 polymorphism at 7q36.3 region in Uygur population in Xinjiang, China. | Tao J et al. | โ | 2019 | โ |
| Machine Learning SNP Based Prediction for Precision Medicine. | Ho DSW et al. | โ | 2019 | โ |
| Mapping Covariation Quantitative Trait Loci That Control Organ Growth and Whole-Plant Biomass. | Gan J et al. | โ | 2019 | โ |
| Mapping Ethanol Tolerance in Budding Yeast Reveals High Genetic Variation in a Wild Isolate. | Haas R et al. | โ | 2019 | โ |
| Mass Spectrometry-Based Biomarkers in Drug Development. | Robinson MR et al. | โ | 2019 | โ |
| Multiple Changes Underlie Allelic Divergence of <i>CUP2</i> Between <i>Saccharomyces</i> Species. | Li XC et al. | โ | 2019 | โ |
| Multivariate analysis of genome-wide data to identify potential pleiotropic genes for five major psychiatric disorders using MetaCCA. | Jia X et al. | โ | 2019 | โ |
| Natural variation in ZmFBL41 confers banded leaf and sheath blight resistance in maize. | Li N et al. | โ | 2019 | โ |
| Navigating the non-coding genome in heart development and Congenital Heart Disease. | Chahal G et al. | โ | 2019 | โ |
| Neutrophil GM-CSF signaling in inflammatory bowel disease patients is influenced by non-coding genetic variants. | Venkateswaran S et al. | โ | 2019 | โ |
| Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity. | Tang J et al. | โ | 2019 | โ |
| Optimizing the Power to Identify the Genetic Basis of Complex Traits with Evolve and Resequence Studies. | Vlachos C et al. | โ | 2019 | โ |
| Overlapping genetic effects between suicidal ideation and neurocognitive functioning. | Brick LA et al. | โ | 2019 | โ |
| Parenting Interacts with Oxytocin Polymorphisms to Predict Adolescent Social Anxiety Symptom Development: A Novel Polygenic Approach. | Nelemans SA et al. | โ | 2019 | โ |
| Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood. | Khera AV et al. | โ | 2019 | โ |
| Polygenic risk scoring and prediction of mental health outcomes. | Anderson JS et al. | โ | 2019 | โ |
| Polymorphisms of MFGE8 are associated with susceptibility and clinical manifestations through gene expression modulation in Koreans with systemic lupus erythematosus. | Baek WY et al. | โ | 2019 | โ |
| Population-level approaches reveal novel aspects of lignin biosynthesis, content, composition and structure. | Tuskan GA et al. | โ | 2019 | โ |
| Powerful gene set analysis in GWAS with the Generalized Berk-Jones statistic. | Sun R et al. | โ | 2019 | โ |
| Precision Aging: Applying Precision Medicine to the Field of Cognitive Aging. | Ryan L et al. | โ | 2019 | โ |
| Predicting Functional Effects of Synonymous Variants: A Systematic Review and Perspectives. | Zeng Z et al. | โ | 2019 | โ |
| Psychiatric genetics researchers' views on offering return of results to individual participants. | Kostick KM et al. | โ | 2019 | โ |
| Rare-variant collapsing analyses for complex traits: guidelines and applications. | Povysil G et al. | โ | 2019 | โ |
| Recent advances in breeding and genetics for dairy goats. | Gipson TA | โ | 2019 | โ |
| Recent Advances in the Genetics of Fractures in Osteoporosis. | Koromani F et al. | โ | 2019 | โ |
| Region-based interaction detection in genome-wide case-control studies. | Zhang S et al. | โ | 2019 | โ |
| Regulatory variants: from detection to predicting impact. | Rojano E et al. | โ | 2019 | โ |
| Replicability analysis in genome-wide association studies via Cartesian hidden Markov models. | Wang P et al. | โ | 2019 | โ |
| SAFETY: Secure gwAs in Federated Environment through a hYbrid Solution. | Sadat MN et al. | โ | 2019 | โ |
| Scientific Utopia III: Crowdsourcing Science. | Uhlmann EL et al. | โ | 2019 | โ |
| Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization. | Millard LAC et al. | โ | 2019 | โ |
| Sex-specific moderation by lifestyle and psychosocial factors on the genetic contributions to adiposity in 112,151 individuals from UK Biobank. | Calvin CM et al. | โ | 2019 | โ |
| Signals Among Signals: Prioritizing Nongenetic Associations in Massive Data Sets. | Manrai AK et al. | โ | 2019 | โ |
| Single-plant GWAS coupled with bulk segregant analysis allows rapid identification and corroboration of plant-height candidate SNPs. | Gyawali A et al. | โ | 2019 | โ |
| Structural equation modeling for hypertension and type 2 diabetes based on multiple SNPs and multiple phenotypes. | Jeon S et al. | โ | 2019 | โ |
| Sufficient direction factor model and its application to gene expression quantitative trait loci discovery. | Jiang F et al. | โ | 2019 | โ |
| Targeted, High-Resolution RNA Sequencing of Non-coding Genomic Regions Associated With Neuropsychiatric Functions. | Hardwick SA et al. | โ | 2019 | โ |
| The evolutionary potential of diet-dependent effects on lifespan and fecundity in a multi-parental population of Drosophila melanogaster. | Ng'oma E et al. | โ | 2019 | โ |
| The evolution of genetic-based risk scores for lipids and cardiovascular disease. | Dron JS et al. | โ | 2019 | โ |
| The Evolving Field of Genetic Epidemiology: From Familial Aggregation to Genomic Sequencing. | Duggal P et al. | โ | 2019 | โ |
| The Future of Genomic Studies Must Be Globally Representative: Perspectives from PAGE. | Bien SA et al. | โ | 2019 | โ |
| The Genetic Basis of Metabolic Disease. | Barroso I et al. | โ | 2019 | โ |
| The interplay of canonical and noncanonical Wnt signaling in metabolic syndrome. | Abou Ziki MD et al. | โ | 2019 | โ |
| The many (sur)faces of B cells. | Hรคfner SJ | โ | 2019 | โ |
| Thinking About the Evolution of Complex Traits in the Era of Genome-Wide Association Studies. | Sella G et al. | โ | 2019 | โ |
| TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits. | Nagpal S et al. | โ | 2019 | โ |
| Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. | Rowland J et al. | โ | 2019 | โ |
| X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline. | Anguita-Ruiz A et al. | โ | 2019 | โ |
| 8q22.1 Microduplication Syndrome: Why the Brain Should Be Spared? A Literature Review and a Case Report. | Gagliano A et al. | โ | 2018 | โ |
| A Bayesian framework for multiple trait colocalization from summary association statistics. | Giambartolomei C et al. | โ | 2018 | โ |
| Accelerating genetic gains in legumes for the development of prosperous smallholder agriculture: integrating genomics, phenotyping, systems modelling and agronomy. | Varshney RK et al. | โ | 2018 | โ |
| A fine-mapping study of central obesity loci incorporating functional annotation and imputation. | Zhang X et al. | โ | 2018 | โ |
| A genome-wide association study for extremely high intelligence. | Zabaneh D et al. | โ | 2018 | โ |
| Analysis of Epistasis in Natural Traits Using Model Organisms. | Campbell RF et al. | โ | 2018 | โ |
| A network approach to exploring the functional basis of gene-gene epistatic interactions in disease susceptibility. | Yip DK et al. | โ | 2018 | โ |
| A network-based conditional genetic association analysis of the human metabolome. | Tsepilov YA et al. | โ | 2018 | โ |
| Annotating gene sets by mining large literature collections with protein networks. | Wang S et al. | โ | 2018 | โ |
| An Overview of Genome-Wide Association Studies. | Chang M et al. | โ | 2018 | โ |
| A population genetic interpretation of GWAS findings for human quantitative traits. | Simons YB et al. | โ | 2018 | โ |
| Applications and efficiencies of the first cat 63K DNA array. | Gandolfi B et al. | โ | 2018 | โ |
| Applying family analyses to electronic health records to facilitate genetic research. | Huang X et al. | โ | 2018 | โ |
| A robust and powerful two-step testing procedure for local ancestry adjusted allelic association analysis in admixed populations. | Duan Q et al. | โ | 2018 | โ |
| Assessing Rare Variation in Complex Traits. | Kuchenbaecker K et al. | โ | 2018 | โ |
| Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study. | Trajanoska K et al. | โ | 2018 | โ |
| Association analysis of multiple traits by an approach of combining P values. | Chen L et al. | โ | 2018 | โ |
| Association between COMT Val158Met and psychiatric disorders: A comprehensive meta-analysis. | Taylor S | โ | 2018 | โ |
| Association detection between ordinal trait and rare variants based on adaptive combination of P values. | Wang M et al. | โ | 2018 | โ |
| Assortative mating on complex traits revisited: Double first cousins and the X-chromosome. | Yengo L et al. | โ | 2018 | โ |
| A tutorial on conducting genome-wide association studies: Quality control and statistical analysis. | Marees AT et al. | โ | 2018 | โ |
| Big Data's Role in Precision Public Health. | Dolley S | โ | 2018 | โ |
| Biomedical informatics and machine learning for clinical genomics. | Diao JA et al. | โ | 2018 | โ |
| Cancer epigenetics: Moving forward. | Nebbioso A et al. | โ | 2018 | โ |
| Cardiomyopathy and Preeclampsia. | Gammill HS et al. | โ | 2018 | โ |
| Chemotherapy-Related Cardiac Dysfunction: A Systematic Review of Genetic Variants Modulating Individual Risk. | Linschoten M et al. | โ | 2018 | โ |
| Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden. | Eriksson D et al. | โ | 2018 | โ |
| Comparison of methods for transcriptome imputation through application to two common complex diseases. | Fryett JJ et al. | โ | 2018 | โ |
| Complex Haplotypes of <i>GSTM1</i> Gene Deletions Harbor Signatures of a Selective Sweep in East Asian Populations. | Saitou M et al. | โ | 2018 | โ |
| Computational mechanisms in genetic regulation by RNA. | Deutsch JM | โ | 2018 | โ |
| Contrasting results from GWAS and QTL mapping on wing length in great reed warblers. | Hansson B et al. | โ | 2018 | โ |
| Critical Evaluation of Data Requires Rigorous but Broadly Based Statistical Inference. | Cox NJ et al. | โ | 2018 | โ |
| Cultural primer for cardiometabolic health: health disparities, structural factors, community, pathways to improvement, and clinical applications. | Kones R et al. | โ | 2018 | โ |
| Determining Genetic Causal Variants Through Multivariate Regression Using Mixture Model Penalty. | Sundar VS et al. | โ | 2018 | โ |
| Differential gene expression is not required for facultative sex allocation: a transcriptome analysis of brain tissue in the parasitoid wasp <i>Nasonia vitripennis</i>. | Cook N et al. | โ | 2018 | โ |
| Drug development in the era of precision medicine. | Dugger SA et al. | โ | 2018 | โ |
| Embracing polygenicity: a review of methods and tools for psychiatric genetics research. | Maier RM et al. | โ | 2018 | โ |
| Empirical Comparisons of Different Statistical Models To Identify and Validate Kernel Row Number-Associated Variants from Structured Multi-parent Mapping Populations of Maize. | Yang J et al. | โ | 2018 | โ |
| Endometriosis. | Zondervan KT et al. | โ | 2018 | โ |
| Evaluation of a phenotype imputation approach using GAW20 simulated data. | Chen Y et al. | โ | 2018 | โ |
| Exploiting next-generation sequencing to solve the haplotyping puzzle in polyploids: a simulation study. | Motazedi E et al. | โ | 2018 | โ |
| Extending Causality Tests with Genetic Instruments: An Integration of Mendelian Randomization with the Classical Twin Design. | Minicฤ CC et al. | โ | 2018 | โ |
| From lipid locus to drug target through human genomics. | van der Laan SW et al. | โ | 2018 | โ |
| Functional Validation of Candidate Genes Detected by Genomic Feature Models. | Rohde PD et al. | โ | 2018 | โ |
| GCAT|Genomes for life: a prospective cohort study of the genomes of Catalonia. | Obรณn-Santacana M et al. | โ | 2018 | โ |
| Genetic Approaches to the Study of Gene Variants and Their Impact on the Pathophysiology of Type 2 Diabetes. | Szabo M et al. | โ | 2018 | โ |
| Genetic architecture: the shape of the genetic contribution to human traits and disease. | Timpson NJ et al. | โ | 2018 | โ |
| Genetic cartography of longevity in humans and mice: Current landscape and horizons. | Hook M et al. | โ | 2018 | โ |
| Genetic Correlation Profile of Schizophrenia Mirrors Epidemiological Results and Suggests Link Between Polygenic and Rare Variant (22q11.2) Cases of Schizophrenia. | Duncan LE et al. | โ | 2018 | โ |
| Genetic determinants of co-accessible chromatin regions in activated T cells across humans. | Gate RE et al. | โ | 2018 | โ |
| Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty. | Sathyan S et al. | โ | 2018 | โ |
| Genetic Regulation of the Thymic Stromal Lymphopoietin (TSLP)/TSLP Receptor (TSLPR) Gene Expression and Influence of Epistatic Interactions Between IL-33 and the TSLP/TSLPR Axis on Risk of Coronary Artery Disease. | Nie SF et al. | โ | 2018 | โ |
| Genetic risk score for adult body mass index associations with childhood and adolescent weight gain in an African population. | Munthali RJ et al. | โ | 2018 | โ |
| Genetic variants influence on the placenta regulatory landscape. | Delahaye F et al. | โ | 2018 | โ |
| Genetic Variation and the Electrocardiograph: From Genome-Wide Association Studies to the Patient. | Hedley PL et al. | โ | 2018 | โ |
| Genome sequencing in the clinic: the past, present, and future of genomic medicine. | Prokop JW et al. | โ | 2018 | โ |
| Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. | Wray NR et al. | โ | 2018 | โ |
| Genome-wide association study identifies loci and candidate genes for internal organ weights in Simmental beef cattle. | An B et al. | โ | 2018 | โ |
| Genomewide association study reveals novel genetic loci associated with change in renal function in heart transplant recipients. | Asleh R et al. | โ | 2018 | โ |
| GWAS for BMI: a treasure trove of fundamental insights into the genetic basis of obesity. | Speakman JR et al. | โ | 2018 | โ |
| GWAS signals revisited using human knockouts. | Maddirevula S et al. | โ | 2018 | โ |
| Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study. | Muรฑoz ML et al. | โ | 2018 | โ |
| Higher Polygenetic Predisposition for Asthma in Cow's Milk Allergic Children. | Jansen PR et al. | โ | 2018 | โ |
| Host genetics and microbiome associations through the lens of genome wide association studies. | Weissbrod O et al. | โ | 2018 | โ |
| How Genomics Is Personalizing the Management of Dyslipidemia and Cardiovascular Disease Prevention. | Benes LB et al. | โ | 2018 | โ |
| Human amylase gene copy number variation as a determinant of metabolic state. | Elder PJD et al. | โ | 2018 | โ |
| Identification of Alzheimer's Disease-Related Genes Based on Data Integration Method. | Hu Y et al. | โ | 2018 | โ |
| Identification of an Amino Acid Motif in HLA-DRฮฒ1 That Distinguishes Uveitis in Patients With Juvenile Idiopathic Arthritis. | Haasnoot AJW et al. | โ | 2018 | โ |
| Identification of <i>ST3AGL4</i>, <i>MFHAS1, CSNK2A2</i> and <i>CD226</i> as loci associated with systemic lupus erythematosus (SLE) and evaluation of SLE genetics in drug repositioning. | Wang YF et al. | โ | 2018 | โ |
| Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method. | Hu Y et al. | โ | 2018 | โ |
| Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. | Qi T et al. | โ | 2018 | โ |
| iMEGES: integrated mental-disorder GEnome score by deep neural network for prioritizing the susceptibility genes for mental disorders in personal genomes. | Khan A et al. | โ | 2018 | โ |
| Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression. | Schmiedel BJ et al. | โ | 2018 | โ |
| Improved ethical guidance for the return of results from psychiatric genomics research. | Lรกzaro-Muรฑoz G et al. | โ | 2018 | โ |
| Improving genetic prediction by leveraging genetic correlations among human diseases and traits. | Maier RM et al. | โ | 2018 | โ |
| Improving machine learning reproducibility in genetic association studies with proportional instance cross validation (PICV). | Piette ER et al. | โ | 2018 | โ |
| Insights and Implications of Genome-Wide Association Studies of Height. | Guo MH et al. | โ | 2018 | โ |
| Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity. | Sakaue S et al. | โ | 2018 | โ |
| Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits. | Wu Y et al. | โ | 2018 | โ |
| Integrative omics for health and disease. | Karczewski KJ et al. | โ | 2018 | โ |
| Kernel machine methods for integrative analysis of genome-wide methylation and genotyping studies. | Zhao N et al. | โ | 2018 | โ |
| Largest GWAS of PTSD (N=20โ070) yields genetic overlap with schizophrenia and sex differences in heritability. | Duncan LE et al. | โ | 2018 | โ |
| Mapping Causal Variants with Single-Nucleotide Resolution Reveals Biochemical Drivers of Phenotypic Change. | She R et al. | โ | 2018 | โ |
| Meta-Analysis of Common and Rare Variants. | Michailidou K | โ | 2018 | โ |
| Meta-analysis of genome-wide association studies for height and body mass index in โผ700000 individuals of European ancestry. | Yengo L et al. | โ | 2018 | โ |
| Methods for fine-mapping with chromatin and expression data. | Roytman M et al. | โ | 2018 | โ |
| Method to estimate the approximate samples size that yield a certain number of significant GWAS signals in polygenic traits. | Bacanu SA et al. | โ | 2018 | โ |
| Mitochondrial - nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivo. | Dunham-Snary KJ et al. | โ | 2018 | โ |
| Monitoring Neurodegeneration in Glaucoma: Therapeutic Implications. | Ban N et al. | โ | 2018 | โ |
| Multi-polygenic score approach to trait prediction. | Krapohl E et al. | โ | 2018 | โ |
| Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment. | Shadrin AA et al. | โ | 2018 | โ |
| Omics, big data and machine learning as tools to propel understanding of biological mechanisms and to discover novel diagnostics and therapeutics. | Perakakis N et al. | โ | 2018 | โ |
| PARP-1 Inhibition Rescues Short Lifespan in Hyperglycemic <i>C. Elegans</i> And Improves GLP-1 Secretion in Human Cells. | Xia Q et al. | โ | 2018 | โ |
| Performance of epistasis detection methods in semi-simulated GWAS. | Chatelain C et al. | โ | 2018 | โ |
| Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies. | Derkach A et al. | โ | 2018 | โ |
| Precision medicine in diabetes: an opportunity for clinical translation. | Merino J et al. | โ | 2018 | โ |
| Predicting cardiovascular disease in familial hypercholesterolemia. | Paquette M et al. | โ | 2018 | โ |
| Probabilistic natural mapping of gene-level tests for genome-wide association studies. | Bao F et al. | โ | 2018 | โ |
| Quantifying how constraints limit the diversity of viable routes to adaptation. | Yeaman S et al. | โ | 2018 | โ |
| Real-life helping behaviours in North America: A genome-wide association approach. | Primes G et al. | โ | 2018 | โ |
| Replicability and Prediction: Lessons and Challenges from GWAS. | Marigorta UM et al. | โ | 2018 | โ |
| Robust Findings From 25ย Years of PTSD Genetics Research. | Duncan LE et al. | โ | 2018 | โ |
| Screening for gene-environment (GรE) interaction using omics data from exposed individuals: an application to gene-arsenic interaction. | Argos M et al. | โ | 2018 | โ |
| Sepsis: Personalized Medicine Utilizing 'Omic' Technologies-A Paradigm Shift? | Itenov TS et al. | โ | 2018 | โ |
| Shortcut to success? Negotiating genetic uniqueness in global biomedicine. | Tarkkala H et al. | โ | 2018 | โ |
| SimPEL: Simulation-based power estimation for sequencing studies of low-prevalence conditions. | Mak L et al. | โ | 2018 | โ |
| Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease. | Hook PW et al. | โ | 2018 | โ |
| Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs. | van der Wijst MGP et al. | โ | 2018 | โ |
| Sociogenomics in the 21<sup>st</sup> Century: An Introduction to the History and Potential of Genetically-informed Social Science. | Braudt DB | โ | 2018 | โ |
| Subset-Based Analysis Using Gene-Environment Interactions for Discovery of Genetic Associations across Multiple Studies or Phenotypes. | Yu Y et al. | โ | 2018 | โ |
| Tantalizing dilemma in risk prediction from disease scoring statistics. | Awany D et al. | โ | 2018 | โ |
| The accuracy of LD Score regression as an estimator of confounding and genetic correlations in genome-wide association studies. | Lee JJ et al. | โ | 2018 | โ |
| The Genetic Sphygmomanometer: an argument for routine genome-wide genotyping in the population and a new view on its use to inform clinical practice. | Timpson NJ et al. | โ | 2018 | โ |
| The Genotype-Phenotype Relationships in the Light of Natural Selection. | Chen H et al. | โ | 2018 | โ |
| The impact of genome-wide association studies on biomedical research publications. | Struck TJ et al. | โ | 2018 | โ |
| The MR-Base platform supports systematic causal inference across the human phenome. | Hemani G et al. | โ | 2018 | โ |
| The personal and clinical utility of polygenic risk scores. | Torkamani A et al. | โ | 2018 | โ |
| The ubiquity of pleiotropy in human disease. | Chesmore K et al. | โ | 2018 | โ |
| Trans-eQTLs identified in whole blood have limited influence on complex disease biology. | Yap CX et al. | โ | 2018 | โ |
| Transethnic differences in GWAS signals: A simulation study. | Zanetti D et al. | โ | 2018 | โ |
| Understanding the development of psychopathy: progress and challenges. | Viding E et al. | โ | 2018 | โ |
| Unsupervised, Statistically Based Systems Biology Approach for Unraveling the Genetics of Complex Traits: A Demonstration with Ethanol Metabolism. | Lusk R et al. | โ | 2018 | โ |
| Using deep learning to model the hierarchical structure and function of a cell. | Ma J et al. | โ | 2018 | โ |
| Using Genomic Data to Find Disease-Modifying Loci in Huntington's Disease (HD). | Holmans P et al. | โ | 2018 | โ |
| Voluntary exposure to a toxin: the genetic influence on ethanol consumption. | Hoffman PL et al. | โ | 2018 | โ |
| Weight or metabolism: which deserve more attention in obesity? | Zhu B et al. | โ | 2018 | โ |
| Wild GWAS-association mapping in natural populations. | Santure AW et al. | โ | 2018 | โ |
| WISH-R- a fast and efficient tool for construction of epistatic networks for complex traits and diseases. | Carmelo VAO et al. | โ | 2018 | โ |
| 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. | Gorski M et al. | โ | 2017 | โ |
| 10 Years of GWAS Discovery: Biology, Function, and Translation. | Visscher PM et al. | โ | 2017 | โ |
| A comparison of methods for inferring causal relationships between genotype and phenotype using additional biological measurements. | Ainsworth HF et al. | โ | 2017 | โ |
| A continuum of genetic liability for minor and major depression. | Corfield EC et al. | โ | 2017 | โ |
| ACTH and Polymorphisms at Steroidogenic Loci as Determinants of Aldosterone Secretion and Blood Pressure. | MacKenzie SM et al. | โ | 2017 | โ |
| Adiponectin promoter polymorphisms are predictors of lipid profile improvement after bariatric surgery. | Gasparotto AS et al. | โ | 2017 | โ |
| A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus. | Kumar D et al. | โ | 2017 | โ |
| A Genome-Wide Association Study Identifies the Genomic Region Associated with Shell Color in Yesso Scallop, Patinopecten yessoensis. | Zhao L et al. | โ | 2017 | โ |
| A <i>Drosophila</i> model of insulin resistance associated with the human TRIB3 Q/R polymorphism. | Fischer Z et al. | โ | 2017 | โ |
| A method for integrating neuroimaging into genetic models of learning performance. | Mehta CM et al. | โ | 2017 | โ |
| A method to customize population-specific arrays for genome-wide association testing. | Ehli EA et al. | โ | 2017 | โ |
| A microsatellite diversity analysis and the development of core-set germplasm in a large hulless barley (Hordeum vulgare L.) collection. | Xu Q et al. | โ | 2017 | โ |
| A Model of Compound Heterozygous, Loss-of-Function Alleles Is Broadly Consistent with Observations from Complex-Disease GWAS Datasets. | Sanjak JS et al. | โ | 2017 | โ |
| Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data. | Polushina T et al. | โ | 2017 | โ |
| Applications of the 1000 Genomes Project resources. | Zheng-Bradley X et al. | โ | 2017 | โ |
| A Scalable Bayesian Method for Integrating Functional Information in Genome-wide Association Studies. | Yang J et al. | โ | 2017 | โ |
| Association of variants in SH2B1 and RABEP1 with worsening of low-density lipoprotein and glucose parameters in patients treated with psychotropic drugs. | Delacrรฉtaz A et al. | โ | 2017 | โ |
| Associations between genetic risk variants for kidney diseases and kidney disease etiology. | Wunnenburger S et al. | โ | 2017 | โ |
| A Statistical Approach to Fine Mapping for the Identification of Potential Causal Variants Related to Bone Mineral Density. | Greenbaum J et al. | โ | 2017 | โ |
| Bayesian genome- and epigenome-wide association studies with gene level dependence. | Lock EF et al. | โ | 2017 | โ |
| Bioinformatics in translational drug discovery. | Wooller SK et al. | โ | 2017 | โ |
| Biomarkers to Predict Cardiovascular Death. | Dhindsa DS et al. | โ | 2017 | โ |
| Candidate gene molecular markers as tools for analyzing genetic susceptibility to morbillivirus infection in stranded Cetaceans. | Stejskalova K et al. | โ | 2017 | โ |
| cepip: context-dependent epigenomic weighting for prioritization of regulatory variants and disease-associated genes. | Li MJ et al. | โ | 2017 | โ |
| Chronic postsurgical pain: is there a possible genetic link? | James SK | โ | 2017 | โ |
| Cis-SNPs Set Testing and PrediXcan Analysis for Gene Expression Data using Linear Mixed Models. | Zeng P et al. | โ | 2017 | โ |
| CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. | Macรฉ A et al. | โ | 2017 | โ |
| Common shared genetic variation behind decreased risk of breast cancer in celiac disease. | Ugalde-Morales E et al. | โ | 2017 | โ |
| Concepts, estimation and interpretation of SNP-based heritability. | Yang J et al. | โ | 2017 | โ |
| Confidentiality in Biobanking Research: A Comparison of Donor and Nondonor Families' Understanding of Risks. | Siminoff LA et al. | โ | 2017 | โ |
| Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. | Benyamin B et al. | โ | 2017 | โ |
| Current Scope and Challenges in Phenome-Wide Association Studies. | Verma A et al. | โ | 2017 | โ |
| Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence. | Clark SL et al. | โ | 2017 | โ |
| Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits. | Crawford L et al. | โ | 2017 | โ |
| Differential analysis of mutations in the Jewish population and their implications for diseases. | Einhorn Y et al. | โ | 2017 | โ |
| Disease variants alter transcription factor levels and methylation of their binding sites. | Bonder MJ et al. | โ | 2017 | โ |
| Dissecting the genetics of complex traits using summary association statistics. | Pasaniuc B et al. | โ | 2017 | โ |
| Distribution of CYP2C8 and CYP2C9 amino acid substitution alleles in South Indian diabetes patients: A genotypic and computational protein phenotype study. | Rao DK et al. | โ | 2017 | โ |
| Drug enrichment and discovery from schizophrenia genome-wide association results: an analysis and visualisation approach. | Gaspar HA et al. | โ | 2017 | โ |
| Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits. | Yao C et al. | โ | 2017 | โ |
| Editing the genome of hiPSC with CRISPR/Cas9: disease models. | Bassett AR | โ | 2017 | โ |
| Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine. | Johnson KW et al. | โ | 2017 | โ |
| Endophenotype best practices. | Iacono WG et al. | โ | 2017 | โ |
| Environment-Dependent Genotype-Phenotype Associations in Avian Breeding Time. | Gienapp P et al. | โ | 2017 | โ |
| Establishing multiple omics baselines for three Southeast Asian populations in the Singapore Integrative Omics Study. | Saw WY et al. | โ | 2017 | โ |
| Evaluating Sequence-Based Genomic Prediction with an Efficient New Simulator. | Pรฉrez-Enciso M et al. | โ | 2017 | โ |
| Evolutionary interplay between structure, energy and epistasis in the coat protein of the ฯX174 phage family. | Redondo RA et al. | โ | 2017 | โ |
| Exhaustive search for epistatic effects on the human methylome. | Egli T et al. | โ | 2017 | โ |
| Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer. | Ruiz-Pinto S et al. | โ | 2017 | โ |
| Exome Sequence Analysis of 14 Families With High Myopia. | Kloss BA et al. | โ | 2017 | โ |
| Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms. | Amin N et al. | โ | 2017 | โ |
| Exploring regulation in tissues with eQTL networks. | Fagny M et al. | โ | 2017 | โ |
| Exploring the genetic architecture and improving genomic prediction accuracy for mastitis and milk production traits in dairy cattle by mapping variants to hepatic transcriptomic regions responsive to intra-mammary infection. | Fang L et al. | โ | 2017 | โ |
| Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data. | Zhou H et al. | โ | 2017 | โ |
| Fetal de novo mutations and preterm birth. | Li J et al. | โ | 2017 | โ |
| Fifteen years of quantitative trait loci studies in fish: challenges and future directions. | Ashton DT et al. | โ | 2017 | โ |
| Forensically relevant SNaPshot<sup>ยฎ</sup> assays for human DNA SNP analysis: a review. | Mehta B et al. | โ | 2017 | โ |
| Functional mapping and annotation of genetic associations with FUMA. | Watanabe K et al. | โ | 2017 | โ |
| Further evidence for genetic variation at the serotonin transporter gene SLC6A4 contributing toward anxiety. | Forstner AJ et al. | โ | 2017 | โ |
| Fusion pore in exocytosis: More than an exit gate? A ฮฒ-cell perspective. | Hastoy B et al. | โ | 2017 | โ |
| Gender differences and the role of parental education, school types and migration on the body mass index of 2930 Austrian school children : A cross-sectional study. | Furthner D et al. | โ | 2017 | โ |
| Gene discovery in amyotrophic lateral sclerosis: implications for clinical management. | Al-Chalabi A et al. | โ | 2017 | โ |
| Gene set selection via LASSO penalized regression (SLPR). | Frost HR et al. | โ | 2017 | โ |
| Gene therapy for diabetic retinopathy: Are we ready to make the leap from bench to bedside? | Wang JH et al. | โ | 2017 | โ |
| Genetic and environmental risk factors for chronic kidney disease. | Obrador GT et al. | โ | 2017 | โ |
| Genetic and environmental risk factors for developmental dyslexia in children: systematic review of the last decade. | Becker N et al. | โ | 2017 | โ |
| Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era. | Do C et al. | โ | 2017 | โ |
| Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia. | Devor A et al. | โ | 2017 | โ |
| Genetic modifiers of Mendelian disease: Huntington's disease and the trinucleotide repeat disorders. | Holmans PA et al. | โ | 2017 | โ |
| Genetic Programming of Hypertension. | Ahn SY et al. | โ | 2017 | โ |
| Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits. | Civelek M et al. | โ | 2017 | โ |
| Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies. | McGraw CM et al. | โ | 2017 | โ |
| Genetics and educational attainment. | Cesarini D et al. | โ | 2017 | โ |
| Genetics of Migraine: Insights into the Molecular Basis of Migraine Disorders. | Sutherland HG et al. | โ | 2017 | โ |
| Genetic variation at 16q24.2 is associated with small vessel stroke. | Traylor M et al. | โ | 2017 | โ |
| Genome-Wide Association Analyses Based on Broadly Different Specifications for Prior Distributions, Genomic Windows, and Estimation Methods. | Chen C et al. | โ | 2017 | โ |
| Genome-wide Association Studies in Maize: Praise and Stargaze. | Xiao Y et al. | โ | 2017 | โ |
| Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior. | Tielbeek JJ et al. | โ | 2017 | โ |
| Genome-wide association study for cheese yield and curd nutrient recovery in dairy cows. | Dadousis C et al. | โ | 2017 | โ |
| Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy. | Marenholz I et al. | โ | 2017 | โ |
| Genome-wide association study of rust traits in orchardgrass using SLAF-seq technology. | Zeng B et al. | โ | 2017 | โ |
| Genome-Wide Polygenic Scores Predict Reading Performance Throughout the School Years. | Selzam S et al. | โ | 2017 | โ |
| Genome-wide Target Enrichment-aided Chip Design: a 66โK SNP Chip for Cashmere Goat. | Qiao X et al. | โ | 2017 | โ |
| Genomic Characteristics of Gender Dysphoria Patients and Identification of Rare Mutations in RYR3 Gene. | Yang F et al. | โ | 2017 | โ |
| Genotype-covariate interaction effects and the heritability of adult body mass index. | Robinson MR et al. | โ | 2017 | โ |
| GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. | Trampush JW et al. | โ | 2017 | โ |
| GW-SEM: A Statistical Package to Conduct Genome-Wide Structural Equation Modeling. | Verhulst B et al. | โ | 2017 | โ |
| Heritability Estimation using a Regularized Regression Approach (HERRA): Applicable to continuous, dichotomous or age-at-onset outcome. | Gorfine M et al. | โ | 2017 | โ |
| Heritability, parental transmission and environment correlation of pediatric-onset type 2 diabetes mellitus and metabolic syndrome-related traits. | Miranda-Lora AL et al. | โ | 2017 | โ |
| How Sensitive Is Genetic Data? | Sariyar M et al. | โ | 2017 | โ |
| Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis. | Wang L et al. | โ | 2017 | โ |
| Identification of breast cancer associated variants that modulate transcription factor binding. | Liu Y et al. | โ | 2017 | โ |
| Identification of Candidate Genes for Reactivity in Guzerat (Bos indicus) Cattle: A Genome-Wide Association Study. | Dos Santos FC et al. | โ | 2017 | โ |
| Identifying genetic variants that affect viability in large cohorts. | Mostafavi H et al. | โ | 2017 | โ |
| IGESS: a statistical approach to integrating individual-level genotype data and summary statistics in genome-wide association studies. | Dai M et al. | โ | 2017 | โ |
| Imbalance-Aware Machine Learning for Predicting Rare and Common Disease-Associated Non-Coding Variants. | Schubach M et al. | โ | 2017 | โ |
| Improved methods for multi-trait fine mapping of pleiotropic risk loci. | Kichaev G et al. | โ | 2017 | โ |
| Inclusion of biological knowledge in a Bayesian shrinkage model for joint estimation of SNP effects. | Pereira M et al. | โ | 2017 | โ |
| Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. | Warren CR et al. | โ | 2017 | โ |
| Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health. | Manrai AK et al. | โ | 2017 | โ |
| Integrating Sequence-based GWAS and RNA-Seq Provides Novel Insights into the Genetic Basis of Mastitis and Milk Production in Dairy Cattle. | Fang L et al. | โ | 2017 | โ |
| Interplay between genetic and epigenetic mechanisms in rheumatoid arthritis. | Frank-Bertoncelj M et al. | โ | 2017 | โ |
| KNN-MDR: a learning approach for improving interactions mapping performances in genome wide association studies. | Abo Alchamlat S et al. | โ | 2017 | โ |
| Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure. | Chen CH et al. | โ | 2017 | โ |
| Linking the Epigenome with Exposure Effects and Susceptibility: The Epigenetic Seed and Soil Model. | Bowers EC et al. | โ | 2017 | โ |
| LLR: a latent low-rank approach to colocalizing genetic risk variants in multiple GWAS. | Liu J et al. | โ | 2017 | โ |
| <i>Trans</i>-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the <i>ANGPTL8</i> HDL-C GWAS Locus. | Cannon ME et al. | โ | 2017 | โ |
| Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies. | de Vlaming R et al. | โ | 2017 | โ |
| Microbial genome-wide association studies: lessons from human GWAS. | Power RA et al. | โ | 2017 | โ |
| Migrainomics - identifying brain and genetic markers of migraine. | Nyholt DR et al. | โ | 2017 | โ |
| Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study. | Nolte IM et al. | โ | 2017 | โ |
| Molecular Aspects of Wound Healing and the Rise of Venous Leg Ulceration: Omics Approaches to Enhance Knowledge and Aid Diagnostic Discovery. | Broszczak DA et al. | โ | 2017 | โ |
| Molecular Genetics of Neurodegenerative Dementias. | Hinz FI et al. | โ | 2017 | โ |
| Morbidity and mortality associated with obesity. | Abdelaal M et al. | โ | 2017 | โ |
| Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals From 124 Cohorts: Design and Rationale. | Rao DC et al. | โ | 2017 | โ |
| Multilocus approaches for the measurement of selection on correlated genetic loci. | Gompert Z et al. | โ | 2017 | โ |
| Multivariate simulation framework reveals performance of multi-trait GWAS methods. | Porter HF et al. | โ | 2017 | โ |
| Naturally Segregating Variation at <i>Ugt86Dd</i> Contributes to Nicotine Resistance in <i>Drosophila melanogaster</i>. | Highfill CA et al. | โ | 2017 | โ |
| Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons. | Zdraljevic S et al. | โ | 2017 | โ |
| Nighttime snacking is associated with risk of obesity and hyperglycemia in adults: a cross-sectional survey from Chinese adult teachers. | Liu XY et al. | โ | 2017 | โ |
| No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes. | Johnson EC et al. | โ | 2017 | โ |
| Novel Candidate Genes Underlying Extreme Trophic Specialization in Caribbean Pupfishes. | McGirr JA et al. | โ | 2017 | โ |
| Novel Common Variants Associated with Obesity and Type 2 Diabetes Detected Using a cFDR Method. | Zhang Q et al. | โ | 2017 | โ |
| Obstacles to Translating Genotype-Phenotype Correlates in Metabolic Disease. | Sharma A et al. | โ | 2017 | โ |
| Omics-based biomarkers: current status and potential use in the clinic. | Quezada H et al. | โ | 2017 | โ |
| Opportunities and Challenges for Environmental Exposure Assessment in Population-Based Studies. | Patel CJ et al. | โ | 2017 | โ |
| Osteoarthritis year in review 2016: genetics, genomics and epigenetics. | van Meurs JB | โ | 2017 | โ |
| Precise Network Modeling of Systems Genetics Data Using the Bayesian Network Webserver. | Ziebarth JD et al. | โ | 2017 | โ |
| Precision Dentistry in Early Childhood: The Central Role of Genomics. | Divaris K | โ | 2017 | โ |
| Predicting educational achievement from DNA. | Selzam S et al. | โ | 2017 | โ |
| Prediction of gene expression with cis-SNPs using mixed models and regularization methods. | Zeng P et al. | โ | 2017 | โ |
| Preliminary Evidence for an Association Between Variants of the Catechol-O-Methyltransferase (COMT) Gene and Premature Ejaculation. | Jern P et al. | โ | 2017 | โ |
| Prioritizing tests of epistasis through hierarchical representation of genomic redundancies. | Cowman T et al. | โ | 2017 | โ |
| Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Large-Scale Epidemiology: A Primer on -Omic Technologies. | Wรผrtz P et al. | โ | 2017 | โ |
| Rapid Adaptation of a Polygenic Trait After a Sudden Environmental Shift. | Jain K et al. | โ | 2017 | โ |
| Regulatory dynamics of 11p13 suggest a role for EHF in modifying CF lung disease severity. | Stolzenburg LR et al. | โ | 2017 | โ |
| Response to the commentary on 'A genome-wide association study in Caucasian women suggests the involvement of HLA gene in the severity of facial solar lentigines'. | Laville V et al. | โ | 2017 | โ |
| Rethinking ovarian cancer genomics: where genome-wide association studies stand? | Pinto R et al. | โ | 2017 | โ |
| Schizophrenia genetics comes to translation. | Domenici E | โ | 2017 | โ |
| Sexual dimorphisms in genetic loci linked to body fat distribution. | Pulit SL et al. | โ | 2017 | โ |
| Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa. | Duncan L et al. | โ | 2017 | โ |
| Simultaneous inference of phenotype-associated genes and relevant tissues from GWAS data via Bayesian integration of multiple tissue-specific gene networks. | Wu M et al. | โ | 2017 | โ |
| SNPing Away at the Genetic Risk for Acute Kidney Injury. | Meyer NJ | โ | 2017 | โ |
| Speech and Language: Translating the Genome. | Deriziotis P et al. | โ | 2017 | โ |
| Stability of Proteins in Dried Blood Spot Biobanks. | Bjรถrkesten J et al. | โ | 2017 | โ |
| Stepwise Distributed Open Innovation Contests for Software Development: Acceleration of Genome-Wide Association Analysis. | Hill A et al. | โ | 2017 | โ |
| Strong epistatic and additive effects of linked candidate SNPs for Drosophila pigmentation have implications for analysis of genome-wide association studies results. | Gibert JM et al. | โ | 2017 | โ |
| The FER rs4957796 TT genotype is associated with unfavorable 90-day survival in Caucasian patients with severe ARDS due to pneumonia. | Hinz J et al. | โ | 2017 | โ |
| The Generalized Higher Criticism for Testing SNP-Set Effects in Genetic Association Studies. | Barnett I et al. | โ | 2017 | โ |
| The Genetic Architecture of Gene Expression in Peripheral Blood. | Lloyd-Jones LR et al. | โ | 2017 | โ |
| The genetic epidemiology of substance use disorder: A review. | Prom-Wormley EC et al. | โ | 2017 | โ |
| The genomic potential of the Aspirin in Reducing Events in the Elderly and Statins in Reducing Events in the Elderly studies. | Lacaze P et al. | โ | 2017 | โ |
| The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches. | Motta BM et al. | โ | 2017 | โ |
| The MassARRAY<sup>ยฎ</sup> System for Targeted SNP Genotyping. | Ellis JA et al. | โ | 2017 | โ |
| The mountainous Cretan dietary patterns and their relationship with cardiovascular risk factors: the Hellenic Isolated Cohorts MANOLIS study. | Farmaki AE et al. | โ | 2017 | โ |
| The role of genomics in common variable immunodeficiency disorders. | Kienzler AK et al. | โ | 2017 | โ |
| Translating Polygenic Analysis for Prevention: From Who to How. | Belsky DW | โ | 2017 | โ |
| Transmission of Metabolic Dysfunction Across Generations. | Jaeger K et al. | โ | 2017 | โ |
| Two approaches reveal a new paradigm of 'switchable or genetics-influenced allele-specific DNA methylation' with potential in human disease. | Martos SN et al. | โ | 2017 | โ |
| Type 1 diabetes genome-wide association studies: not to be lost in translation. | Pociot F | โ | 2017 | โ |
| Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology. | Mechanic LE et al. | โ | 2017 | โ |
| Using GWAS to identify novel therapeutic targets for osteoporosis. | Sabik OL et al. | โ | 2017 | โ |
| What can genome-wide association studies tell us about the evolutionary forces maintaining genetic variation for quantitative traits? | Josephs EB et al. | โ | 2017 | โ |
| What do polymorphisms tell us about the mechanisms of COPD? | Li Y et al. | โ | 2017 | โ |
| Whole-genome single nucleotide variant distribution on genomic regions and its relationship to major depression. | Yu C et al. | โ | 2017 | โ |
| 17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells. | Schmiedel BJ et al. | โ | 2016 | โ |
| ABAEnrichment: an R package to test for gene set expression enrichment in the adult and developing human brain. | Grote S et al. | โ | 2016 | โ |
| A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records. | Hoffmann TJ et al. | โ | 2016 | โ |
| Analysis with the exome array identifies multiple new independent variants in lipid loci. | Kanoni S et al. | โ | 2016 | โ |
| A Single Nucleotide Polymorphism in the Il17ra Promoter Is Associated with Functional Severity of Ankylosing Spondylitis. | Vidal-Castiรฑeira JR et al. | โ | 2016 | โ |
| Assessment and characterization of phenotypic heterogeneity of anxiety disorders across five large cohorts. | Lee M et al. | โ | 2016 | โ |
| Association of polymorphisms in the aldosterone-regulated sodium reabsorption pathway with blood pressure among Hispanics. | Tayo BO et al. | โ | 2016 | โ |
| Associations between the FKBP5 haplotype, exposure to violence and anxiety in females. | Isaksson J et al. | โ | 2016 | โ |
| Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases. | Franzรฉn O et al. | โ | 2016 | โ |
| Colocalization of GWAS and eQTL Signals Detects Target Genes. | Hormozdiari F et al. | โ | 2016 | โ |
| Combined Linkage and Association Mapping Reveals QTL and Candidate Genes for Plant and Ear Height in Maize. | Li X et al. | โ | 2016 | โ |
| Combining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies. | Mieth B et al. | โ | 2016 | โ |
| Embracing Complex Associations in Common Traits: Critical Considerations for Precision Medicine. | Hall MA et al. | โ | 2016 | โ |
| Evaluation of results from genome-wide studies of language and reading in a novel independent dataset. | Carrion-Castillo A et al. | โ | 2016 | โ |
| Exploring Relationships between Host Genome and Microbiome: New Insights from Genome-Wide Association Studies. | Abdul-Aziz MA et al. | โ | 2016 | โ |
| Factor XIII-A transglutaminase deficient mice show signs of metabolically healthy obesity on high fat diet. | Myneni VD et al. | โ | 2016 | โ |
| Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits. | Bakshi A et al. | โ | 2016 | โ |
| Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth. | Brubaker D et al. | โ | 2016 | โ |
| Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression. | Boortz KA et al. | โ | 2016 | โ |
| Gene set analysis for interpreting genetic studies. | Pers TH | โ | 2016 | โ |
| Genetic cardiovascular risk prediction: are we already there? | Assimes TL et al. | โ | 2016 | โ |
| Genetic pleiotropy in complex traits and diseases: implications for genomic medicine. | Gratten J et al. | โ | 2016 | โ |
| Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing. | Nicod J et al. | โ | 2016 | โ |
| Genome-Wide Association Studies for Comb Traits in Chickens. | Shen M et al. | โ | 2016 | โ |
| Genome-Wide Association Study for Muscle Fat Content and Abdominal Fat Traits in Common Carp (Cyprinus carpio). | Zheng X et al. | โ | 2016 | โ |
| Genomic Selection in the <i>Era</i> of Next Generation Sequencing for Complex Traits in Plant Breeding. | Bhat JA et al. | โ | 2016 | โ |
| GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS. | Hoppmann AS et al. | โ | 2016 | โ |
| Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium. | Marinelli M et al. | โ | 2016 | โ |
| Immunoglobulin A nephropathy: a pathophysiology view. | Fabiano RC et al. | โ | 2016 | โ |
| Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells. | Morin A et al. | โ | 2016 | โ |
| Improved Genetic Profiling of Anthropometric Traits Using a Big Data Approach. | Canela-Xandri O et al. | โ | 2016 | โ |
| Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. | Paul DS et al. | โ | 2016 | โ |
| Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years. | Justesen JM et al. | โ | 2016 | โ |
| Integrative analysis of cancer genes in a functional interactome. | Ung MH et al. | โ | 2016 | โ |
| Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases. | Li Y et al. | โ | 2016 | โ |
| MaGelLAn 1.0: a software to facilitate quantitative and population genetic analysis of maternal inheritance by combination of molecular and pedigree information. | Ristov S et al. | โ | 2016 | โ |
| Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. | Shu L et al. | โ | 2016 | โ |
| Meta-Analyses of Genome-Wide Association Data Hold New Promise for Addiction Genetics. | Agrawal A et al. | โ | 2016 | โ |
| Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions. | Hill WD et al. | โ | 2016 | โ |
| Multidimensional heritability analysis of neuroanatomical shape. | Ge T et al. | โ | 2016 | โ |
| Multiple alleles at a single locus control seed dormancy in Swedish <i>Arabidopsis</i>. | Kerdaffrec E et al. | โ | 2016 | โ |
| Multi-strategy genome-wide association studies identify the DCAF16-NCAPG region as a susceptibility locus for average daily gain in cattle. | Zhang W et al. | โ | 2016 | โ |
| Neuroblastoma, a Paradigm for Big Data Science in Pediatric Oncology. | Salazar BM et al. | โ | 2016 | โ |
| Noncoding Genome-Wide Association Studies Variant for Obesity: Inroads Into Mechanism: An Overview From the AHA's Council on Functional Genomics and Translational Biology. | Wu C et al. | โ | 2016 | โ |
| Of the multiple mechanisms leading to type 1 diabetes, T cell receptor revision may play a prominent role (is type 1 diabetes more than a single disease?). | Wagner DH | โ | 2016 | โ |
| 'Omics' biomarkers associated with chronic low back pain: protocol of a retrospective longitudinal study. | Allegri M et al. | โ | 2016 | โ |
| PALME: PAtients Like My gEnome. | Wang L et al. | โ | 2016 | โ |
| PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases. | Ayati M et al. | โ | 2016 | โ |
| Powerful decomposition of complex traits in a diploid model. | Hallin J et al. | โ | 2016 | โ |
| Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits. | Pavlides JM et al. | โ | 2016 | โ |
| Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster. | Okada H et al. | โ | 2016 | โ |
| Rapid phenotyping of knockout mice to identify genetic determinants of bone strength. | Freudenthal B et al. | โ | 2016 | โ |
| Rare mutations and educational attainment. | Cesarini D | โ | 2016 | โ |
| snpGeneSets: An R Package for Genome-Wide Study Annotation. | Mei H et al. | โ | 2016 | โ |
| The critical role of epigenetics in systemic lupus erythematosus and autoimmunity. | Long H et al. | โ | 2016 | โ |
| The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem. | Maadooliat M et al. | โ | 2016 | โ |
| The genetic architecture of resistance to virus infection in Drosophila. | Cogni R et al. | โ | 2016 | โ |
| Transcriptomic Segregation of Human Autoantigens Useful for the Diagnosis of Autoimmune Diseases. | Burbelo PD et al. | โ | 2016 | โ |
| What Drives the Development of Social Inequality Over the Life Course? The German TwinLife Study. | Hahn E et al. | โ | 2016 | โ |