Effects of child maltreatment and inherited liability on antisocial development: an official records study.
- Authors
- Jonson-Reid, Melissa; Presnall, Ned; Drake, Brett; Fox, Louis; Bierut, Laura; Reich, Wendy; Kane, Phyllis; Todd, Richard D; Constantino, John N
- Year
- 2010
- Journal
- Journal of the American Academy of Child and Adolescent Psychiatry
- PMID
- 20410725
- PMCID
- PMC2878182
OBJECTIVE: Evidence is steadily accumulating that a preventable environmental hazard, child maltreatment, exerts causal influences on the development of long-standing patterns of antisocial behavior in humans. The relationship between child maltreatment and antisocial outcome, however, has never previously been tested in a large-scale study in which official reports (rather than family member reports) of child abuse and neglect were incorporated, and genetic influences comprehensively controlled for. METHOD: We cross-referenced official report data on child maltreatment from the Missouri Division of Social Services (DSS) with behavioral data from 4,432 epidemiologically ascertained Missouri twins from the Missouri Twin Registry (MOTWIN). We performed a similar procedure for a clinically ascertained sample of singleton children ascertained from families affected by alcohol dependence participating in the Collaborative Study on the Genetics of Alcoholism (COGA; n = 428) to determine whether associations observed in the general population held true in an "enriched" sample at combined inherited and environmental risk for antisocial development. RESULTS: For both the twin and clinical samples, the additive effects (not interactive effects) of maltreatment and inherited liability on antisocial development were confirmed and were highly statistically significant. CONCLUSIONS: Child maltreatment exhibited causal influence on antisocial outcome when controlling for inherited liability in both the general population and in a clinically ascertained sample. Official report maltreatment data represents a critical resource for resolving competing hypotheses on genetic and environmental causation of child psychopathology, and for assessing intervention outcomes in efforts to prevent antisocial development.
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| Early Life Stress and Childhood Aggression: Mediating and Moderating Effects of Child Callousness and Stress Reactivity. | Winiarski DA et al. | — | 2018 | → |
| Mechanism underlying NMDA blockade-induced inhibition of aggression in post-weaning socially isolated mice. | Chang CH et al. | — | 2018 | → |
| Child Maltreatment and Risk for Psychopathology in Childhood and Adulthood. | Jaffee SR | — | 2017 | → |
| Long-lasting monoaminergic and behavioral dysfunctions in a mice model of socio-environmental stress during adolescence. | de Lima AP et al. | — | 2017 | → |
| Maltreatment-associated neurodevelopmental disorders: a co-twin control analysis. | Dinkler L et al. | — | 2017 | → |
| The Programming of the Social Brain by Stress During Childhood and Adolescence: From Rodents to Humans. | Tzanoulinou S et al. | — | 2017 | → |
| Epigenetic and gene expression changes in the adolescent brain: What have we learned from animal models? | Mychasiuk R et al. | — | 2016 | → |
| Experiences of Domestic and School Violence Among Child and Adolescent Psychiatric Outpatients. | Völkl-Kernstock S et al. | — | 2016 | → |
| Functional consequences of attention-deficit hyperactivity disorder on children and their families. | Usami M | — | 2016 | → |
| Meta-analysis of the serotonin transporter promoter variant (5-HTTLPR) in relation to adverse environment and antisocial behavior. | Tielbeek JJ et al. | — | 2016 | → |
| Post-retrieval extinction in adolescence prevents return of juvenile fear. | Jones CE et al. | — | 2016 | → |
| Social skills and psychopathic traits in maltreated adolescents. | Ometto M et al. | — | 2016 | → |
| Sexually coercive behavior following childhood maltreatment. | Forsman M et al. | — | 2015 | → |
| The co-occurrence of zinc deficiency and social isolation has the opposite effects on mood compared with either condition alone due to changes in the central norepinephrine system. | Mitsuya H et al. | — | 2015 | → |
| Association of the family environment with behavioural and cognitive outcomes in children with chromosome 22q11.2 deletion syndrome. | Allen TM et al. | — | 2014 | → |
| Effects of adverse early-life events on aggression and anti-social behaviours in animals and humans. | Haller J et al. | — | 2014 | → |
| Parent training: equivalent improvement in externalizing behavior for children with and without familial risk. | Presnall N et al. | — | 2014 | → |
| Increased corticosterone in peripubertal rats leads to long-lasting alterations in social exploration and aggression. | Veenit V et al. | — | 2013 | → |
| Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression. | Márquez C et al. | — | 2013 | → |
| Preventive interventions and sustained attachment security in maltreated children. | Stronach EP et al. | — | 2013 | → |
| What time periods of the day are concerning for parents of children with attention deficit hyperactivity disorder? | Usami M et al. | — | 2013 | → |
| From correlates to causes: can quasi-experimental studies and statistical innovations bring us closer to identifying the causes of antisocial behavior? | Jaffee SR et al. | — | 2012 | → |
| Letter from Russia: child abuse and alcohol misuse in a victim. | Jargin SV | — | 2011 | → |
| Emotional and behavioral sequelae of childhood maltreatment. | Perepletchikova F et al. | — | 2010 | → |
| Nature, nurture, and the development and prevention of antisocial behavior problems in children. | Kaufman J | — | 2010 | → |