GRIN1 gene
Evidence from:
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all sources
Related entities (22)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| alcohol | regulates | GRIN1 | 0.002 | 2 |
| alcohol | interacts_with | GRIN1 | 0.32 | 1 |
| APV | targets | GRIN1 | — | 1 |
| Dlg2 | interacts_with | GRIN1 | — | 1 |
| ethanol group | interacts_with | GRIN1 | — | 1 |
| glutamate | interacts_with | GRIN1 | — | 2 |
| GRIN1 | biomarker_for | alcoholism | — | 1 |
| GRIN1 | expressed_in | amygdala | — | 1 |
| GRIN1 | expressed_in | caudate nucleus | — | 1 |
| GRIN1 | expressed_in | cingulate cortex | — | 1 |
| GRIN1 | expressed_in | cortex | — | 1 |
| GRIN1 | interacts_with | glycine | — | 1 |
| GRIN1 | expressed_in | hippocampal dentate gyrus | — | 1 |
| GRIN1 | expressed_in | hippocampus | — | 2 |
| GRIN1 | associated_with | mood disorders | — | 1 |
| GRIN1 | expressed_in | motor cortex | — | 1 |
| GRIN1 | associated_with | NMDA receptor | — | 1 |
| GRIN1 | expressed_in | putamen | — | 1 |
| GRIN1 | expressed_in | striatum | — | 1 |
| GRIN1 | expressed_in | superior frontal cortex | — | 1 |
| N-acetylcysteine | interacts_with | GRIN1 | — | 1 |
| withdrawal | regulates | GRIN1 | — | 1 |
Mentioned in (49)
Papers in which this entity is mentioned.
- Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. (2024)
- Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
- SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics. (2019)
- Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission. (2018)
- Neuroepigenetics and addiction. (2018)
- Regional Differences and Similarities in the Brain Transcriptome for Mice Selected for Ethanol Preference From HS-CC Founders. (2018)
- Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017)
- Genetic studies of alcohol dependence in the context of the addiction cycle. (2017)
- Effects of Antenatal Maternal Depressive Symptoms and Socio-Economic Status on Neonatal Brain Development are Modulated by Genetic Risk. (2017)
- Human Brain Abnormalities Associated With Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder. (2017)
- Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. (2017)
- Sex differences in DNA methylation of the cord blood are related to sex-bias psychiatric diseases. (2017)
- Dysregulation of Cortical Neuron DNA Methylation Profile in Autism Spectrum Disorder. (2017)
- Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace. (2016)
- Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016)
- Prenatal arsenic exposure alters the programming of the glucocorticoid signaling system during embryonic development. (2015)
- The discovery of integrated gene networks for autism and related disorders. (2015)
- Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels. (2015)
- Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex. (2015)
- GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics. (2014)
- The Effects of Arsenic Exposure on Neurological and Cognitive Dysfunction in Human and Rodent Studies: A Review. (2014)
- Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics. (2014)
- Fate analysis of adult hippocampal progenitors in a murine model of fetal alcohol spectrum disorder (FASD). (2013)
- Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. (2013)
- LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype. (2013)
- Rethinking schizophrenia in the context of normal neurodevelopment. (2013)
- Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus. (2013)
- Role of motor cortex NMDA receptors in learning-dependent synaptic plasticity of behaving mice. (2013)
- Synaptic effects induced by alcohol. (2013)
- Does moderate drinking harm the fetal brain? Insights from animal models. (2012)
- Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012)
- Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. (2012)
- Glutamatergic transmission in schizophrenia: from basic research to clinical practice. (2012)
- DISC1 at 10: connecting psychiatric genetics and neuroscience. (2011)
- Administration of memantine during ethanol withdrawal in neonatal rats: effects on long-term ethanol-induced motor incoordination and cerebellar Purkinje cell loss. (2011)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. (2010)
- Postnatal binge-like alcohol exposure decreases dendritic complexity while increasing the density of mature spines in mPFC Layer II/III pyramidal neurons. (2010)
- Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. (2009)
- Neurotoxic effects and biomarkers of lead exposure: a review. (2009)
- Prenatal NAP+SAL prevents developmental delay in a mouse model of Down syndrome through effects on N-methyl-D-aspartic acid and gamma-aminobutyric acid receptors. (2009)
- Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
- HITS-CLIP yields genome-wide insights into brain alternative RNA processing. (2008)
- Chronic alcohol drinking alters neuronal dendritic spines in the brain reward center nucleus accumbens. (2007)
- Decline of the critical period of visual plasticity is concurrent with the reduction of NR2B subunit of the synaptic NMDA receptor in layer 4. (2003)
- Neonatal alcohol exposure induces long-lasting impairment of visual cortical plasticity in ferrets. (2003)
- Relationship between availability of NMDA receptor subunits and their expression at the synapse. (2002)
- In utero cocaine-induced dysfunction of dopamine D1 receptor signaling and abnormal differentiation of cerebral cortical neurons. (2000)
- Effect of enriched environment rearing on impairments in cortical excitability and plasticity after prenatal alcohol exposure. (1999)
Merged raw entities (6)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| grin1 | gene | 49 | 250 |
| glun1 | gene | 7 | 18 |
| nmda receptor nr1 subunit | gene | — | — |
| nmda receptor subunit epsilon-1 | gene | — | — |
| nmdar nr1 subunit | gene | — | — |
| n-methyl-d-aspartic acid receptor subunit nr1 | gene | — | — |