OCD phenotype

Aliases: OCD, OCD patients, OCD risk, OCD symptoms, Obsessive-Compulsive Disorder, Obsessive-compulsive disorder, Obsessive‑Compulsive Disorder, obsessive compulsive disorder, obsessive-compulsive disorder, obsessive‑compulsive disorder, patients, pediatric OCD, primary OCD meta-analysis

Evidence from: primary | all sources

Related entities (146)

Subject	Relation	Object	p-value	Evidence
1000 Genomes Project	associated_with	OCD	—	1
ADHD	associated_with	OCD	—	1
adults	associated_with	OCD	—	1
anhedonia	associated_with	OCD	—	1
anterior cingulate cortex	targets	OCD	—	1
anxiety	associated_with	OCD	—	1
causal variants	risk_factor_for	OCD	—	1
CDH10	associated_with	OCD	—	1
CDH9	associated_with	OCD	—	1
CHD8	risk_factor_for	OCD	0.098	1
CHD8	associated_with	OCD	—	1
CHD8	targets	OCD	—	1
children	associated_with	OCD	—	1
cingulum	targets	OCD	—	1
Cognitive behavioral therapy	associated_with	OCD	—	1
common variants	risk_factor_for	OCD	—	2
common variants	associated_with	OCD	—	1
copy number variations	risk_factor_for	OCD	—	1
cortical surface area	associated_with	OCD	—	1
cortical surface area	biomarker_for	OCD	—	1
cortical thickness	biomarker_for	OCD	—	1
CTNND1	associated_with	OCD	—	1
CTNND1	risk_factor_for	OCD	7.11e-06	1
DALRD3	risk_factor_for	OCD	—	1
deep brain stimulation	interacts_with	OCD	—	1
de novo variant	associated_with	OCD	—	2
de novo variant	risk_factor_for	OCD	0.01	1
depression	associated_with	OCD	—	1
Dlgap1	associated_with	OCD	0.000267	2
Dlgap1	risk_factor_for	OCD	0.000267	1
DLGAP3	risk_factor_for	OCD	—	2
dlPFC	associated_with	OCD	—	2
dopamine	biomarker_for	OCD	—	1
dorsal striatum	targets	OCD	—	1
EGOS	associated_with	OCD	—	1
ENIGMA	associated_with	OCD	—	1
ENIGMA-OCD working group	associated_with	OCD	—	2
eQTLGen Consortium	associated_with	OCD	—	1
EREG	biomarker_for	OCD	0.000306	1
European population	associated_with	OCD	—	1
executive function	associated_with	OCD	—	1
executive functioning	risk_factor_for	OCD	—	1
families	associated_with	OCD	—	1
fear	associated_with	OCD	—	1
fronto-parietal network	associated_with	OCD	—	1
genome-wide significant loci	associated_with	OCD	—	1
GRIA4	associated_with	OCD	—	1
Grid2	associated_with	OCD	1.07e-07	1
GRIK2	risk_factor_for	OCD	—	1
GRIK2	associated_with	OCD	0.045	1
habitual behavior	associated_with	OCD	—	1
HapMap	associated_with	OCD	—	1
heritability	protective_against	OCD	—	1
heritability	associated_with	OCD	—	1
high-frequency rTMS	protective_against	OCD	—	1
histone genes	associated_with	OCD	—	1
HLA	associated_with	OCD	—	1
immune function	associated_with	OCD	—	1
inferior parietal lobe	biomarker_for	OCD	—	1
insula	targets	OCD	—	1
insula	biomarker_for	OCD	—	1
IOCDF-GC	associated_with	OCD	—	1
LDSC	associated_with	OCD	—	1
lead SNP	associated_with	OCD	5e-08	1
LGD	risk_factor_for	OCD	—	1
low-frequency rTMS	protective_against	OCD	—	1
low MAF SNPs	risk_factor_for	OCD	—	1
MAGMA	associated_with	OCD	—	1
medicated patients	associated_with	OCD	—	1
medication	associated_with	OCD	—	1
methylphenidate	risk_factor_for	OCD	—	1
methylphenidate	protective_against	OCD	—	1
missense variants	associated_with	OCD	—	1
MiXeR	associated_with	OCD	—	1
NAcc	associated_with	OCD	—	1
OCD	associated_with	ADHD	—	1
OCD	associated_with	age at first birth	—	1
OCD	associated_with	alcohol abuse	—	1
OCD	protective_against	alcohol dependence	—	1
OCD	associated_with	alpha-gamma PAC	—	1
OCD	associated_with	anorexia nervosa	—	2
OCD	associated_with	anxiety	—	4
OCD	associated_with	autism	—	1
OCD	associated_with	behavioral traits	—	1
OCD	associated_with	body mass index	—	1
OCD	associated_with	brain structure	—	1
OCD	associated_with	comorbidity	—	1
OCD	associated_with	depression	—	1
OCD	associated_with	developmental disorders	—	1
OCD	associated_with	EA	—	1
OCD	associated_with	EGOS	—	1
OCD	associated_with	healthy controls	—	1
OCD	associated_with	height	—	1
OCD	associated_with	hippocampus	—	1
OCD	associated_with	hoarding	—	1
OCD	associated_with	major depressive disorder	—	2
OCD	associated_with	mood disorders	—	1
OCD	risk_factor_for	mortality	—	1
OCD	associated_with	neuropsychiatric disorders	—	1
OCD	associated_with	number of children ever born	—	1
OCD	associated_with	Obsessive-compulsive traits	—	1
OCD	associated_with	phenotype	—	1
OCD	associated_with	PsychENCODE	—	1
OCD	associated_with	psychiatric traits	—	1
OCD	associated_with	Reproductive behavior	—	1
OCD	associated_with	schizophrenia	—	1
OCD	associated_with	smoking	—	1
OCD	associated_with	substance abuse	—	1
OCD	associated_with	Sweden	—	1
OCD	associated_with	Swedish population	—	1
OCD	associated_with	tics	—	1
OCD	associated_with	TS	—	2
OCD risk genes	risk_factor_for	OCD	0.026	2
OCD risk genes	associated_with	OCD	—	1
OCD risk genes	biomarker_for	OCD	—	1
OCGAS	associated_with	OCD	—	1
ondansetron	protective_against	OCD	—	1
orbitofrontal cortex	associated_with	OCD	—	1
parietal cortex	associated_with	OCD	—	1
PsychENCODE	associated_with	OCD	—	1
PTPRD	associated_with	OCD	—	1
rare variant	risk_factor_for	OCD	—	1
rare variation	risk_factor_for	OCD	—	1
response inhibition	associated_with	OCD	—	1
reward system	associated_with	OCD	—	1
risk genes	risk_factor_for	OCD	—	1
rTMS	protective_against	OCD	—	1
selective serotonin reuptake inhibitors	associated_with	OCD	—	1
sex	risk_factor_for	OCD	—	1
SLC1A1	biomarker_for	OCD	—	1
SLC1A1	associated_with	OCD	—	1
SLC1A1	risk_factor_for	OCD	—	1
Slc1a2	associated_with	OCD	—	1
SLITRK1	associated_with	OCD	—	1
SNP	risk_factor_for	OCD	—	1
SNP	associated_with	OCD	—	2
SSRIs	targets	OCD	—	1
SSRIs	protective_against	OCD	—	1
STN	targets	OCD	—	1
structural MRI	biomarker_for	OCD	—	1
Sv2a	associated_with	OCD	—	1
Sweden	associated_with	OCD	—	1
synonymous variant	associated_with	OCD	—	1
TS	associated_with	OCD	—	2
WDR6	risk_factor_for	OCD	—	1
working memory	associated_with	OCD	—	1

Mentioned in (30)

Papers in which this entity is mentioned.

Mapping the genetic landscape across 14 psychiatric disorders. (2026)
Alcohol use disorder is associated with altered frontomedial phase-amplitude coupling strength during resting state. (2026)
Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. (2025)
Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder. (2025)
Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders. (2023)
Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis. (2022)
The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum. (2022)
Mapping brain asymmetry in health and disease through the ENIGMA consortium. (2022)
Closing the life-cycle of normative modeling using federated hierarchical Bayesian regression. (2022)
Toward a neurocircuit-based taxonomy to guide treatment of obsessive-compulsive disorder. (2021)
Structural neuroimaging biomarkers for obsessive-compulsive disorder in the ENIGMA-OCD consortium: medication matters. (2020)
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries. (2020)
De Novo Damaging DNA Coding Mutations Are Associated With Obsessive-Compulsive Disorder and Overlap With Tourette's Disorder and Autism. (2020)
Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders. (2019)
Sex differences in the genetic architecture of obsessive-compulsive disorder. (2019)
Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. (2019)
Heritability of obsessive-compulsive trait dimensions in youth from the general population. (2018)
The anatomy of the human medial forebrain bundle: Ventral tegmental area connections to reward-associated subcortical and frontal lobe regions. (2018)
Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group. (2018)
De Novo Coding Variants Are Strongly Associated with Tourette Disorder. (2017)
Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS. (2015)
Genetics and genomics of psychiatric disease. (2015)
A META-ANALYSIS OF COGNITIVE BEHAVIOR THERAPY AND MEDICATION FOR CHILD OBSESSIVE-COMPULSIVE DISORDER: MODERATORS OF TREATMENT EFFICACY, RESPONSE, AND REMISSION. (2015)
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. (2014)
Linear mixed-effects modeling approach to FMRI group analysis. (2013)
Neuroimaging of child abuse: a critical review. (2012)
Is there an inhibitory-response-control system in the rat? Evidence from anatomical and pharmacological studies of behavioral inhibition. (2010)
A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. (2009)
Genetic and environmental factors in complex neurodevelopmental disorders. (2007)
Adaptive, emotional, and family functioning of children with obsessive-compulsive disorder and comorbid attention deficit hyperactivity disorder. (2005)

Merged raw entities (9)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
ocd	phenotype	27	192
ocd patients	cohort	3	5
patients	phenotype	2	2
pediatric ocd	phenotype	2	2
ocd patients	phenotype	1	1
obsessive‑compulsive disorder	phenotype	—	—
ocd risk	phenotype	—	—
ocd symptoms	phenotype	—	—
primary ocd meta-analysis	phenotype	—	—