neuronal differentiation phenotype

Aliases

differentiation of new cells into neurons

Related entities (27)

Mentioned in (185)

Papers in which this entity is mentioned.

• LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development. (2025)
• Analysis of multi-condition single-cell data with latent embedding multivariate regression. (2025)
• Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. (2025)
• SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms. (2024)
• Transient loss of Polycomb components induces an epigenetic cancer fate. (2024)
• Choline-An Underappreciated Component of a Mother-to-Be's Diet. (2024)
• Effect of schizophrenia common variants on infant brain volumes: cross-sectional study in 207 term neonates in developing Human Connectome Project. (2023)
• A DNA methylation atlas of normal human cell types. (2023)
• Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. (2023)
• Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome. (2023)
• High-throughput detection of craniofacial defects in fluorescent zebrafish. (2023)
• Epigenetics in Alzheimer's Disease. (2022)
• Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. (2022)
• Integrated analysis of multimodal single-cell data. (2021)
• Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence. (2021)
• NGN2 induces diverse neuron types from human pluripotency. (2021)
• A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
• Loss of tumor protein 53 protects against alcohol-induced facial malformations in mice and zebrafish. (2021)
• Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
• Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders. (2021)
• Potential Role of S-Palmitoylation in Cancer Stem Cells of Lung Adenocarcinoma. (2021)
• Inference and analysis of cell-cell communication using CellChat. (2021)
• Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex. (2020)
• Tead transcription factors differentially regulate cortical development. (2020)
• Kcnn2 blockade reverses learning deficits in a mouse model of fetal alcohol spectrum disorders. (2020)
• Choline, Neurological Development and Brain Function: A Systematic Review Focusing on the First 1000 Days. (2020)
• Transcriptome-Wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure. (2020)
• Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
• Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma. (2020)
• Modification of stem cell states by alcohol and acetaldehyde. (2020)
• Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome. (2020)
• Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. (2019)
• Prenatal Developmental Origins of Future Psychopathology: Mechanisms and Pathways. (2019)
• Differentially sensitive neuronal subpopulations in the central nervous system and the formation of hindbrain heterotopias in ethanol-exposed zebrafish. (2019)
• Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure. (2019)
• Prenatal Environment That Affects Neuronal Migration. (2019)
• Hippocampal deficits in neurodevelopmental disorders. (2019)
• Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. (2018)
• Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning. (2018)
• Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE. (2018)
• A compendium of conserved cleavage and polyadenylation events in mammalian genes. (2018)
• Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues. (2018)
• PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
• Neural correlates of verbal memory in youth with heavy prenatal alcohol exposure. (2018)
• Neurotrophins in the Brain: Interaction With Alcohol Exposure During Development. (2017)
• An Update on Non-CB, Non-CB Cannabinoid Related G-Protein-Coupled Receptors. (2017)
• Demystifying the cytokine network: Mathematical models point the way. (2017)
• Prenatal arsenic exposure alters REST/NRSF and microRNA regulators of embryonic neural stem cell fate in a sex-dependent manner. (2017)
• Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1. (2017)
• Postnatal choline supplementation selectively attenuates hippocampal microRNA alterations associated with developmental alcohol exposure. (2017)
• Sex differences in DNA methylation of the cord blood are related to sex-bias psychiatric diseases. (2017)
• Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling. (2017)
• Disconnect between alcohol-induced alterations in chromatin structure and gene transcription in a mouse embryonic stem cell model of exposure. (2017)
• Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. (2017)
• Dysregulation of Cortical Neuron DNA Methylation Profile in Autism Spectrum Disorder. (2017)
• Impact of cytosine methylation on DNA binding specificities of human transcription factors. (2017)
• Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation. (2017)
• Evidence for an immune signature of prenatal alcohol exposure in female rats. (2016)
• Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders. (2016)
• Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin. (2016)
• Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments. (2016)
• Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells. (2016)
• Sustained synchronized neuronal network activity in a human astrocyte co-culture system. (2016)
• Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. (2016)
• Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells. (2016)
• Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis. (2016)
• Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. (2016)
• Zebrafish as a Vertebrate Model System to Evaluate Effects of Environmental Toxicants on Cardiac Development and Function. (2016)
• Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood. (2015)
• Mechanisms of retinoic acid signalling and its roles in organ and limb development. (2015)
• Zebrafish retinal defects induced by ethanol exposure are rescued by retinoic acid and folic acid supplement. (2015)
• Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice. (2015)
• A longitudinal study: changes in cortical thickness and surface area during pubertal maturation. (2015)
• Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. (2015)
• Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells. (2015)
• Fat-Dachsous signaling coordinates cartilage differentiation and polarity during craniofacial development. (2014)
• The Effects of Arsenic Exposure on Neurological and Cognitive Dysfunction in Human and Rodent Studies: A Review. (2014)
• The role of BAF (mSWI/SNF) complexes in mammalian neural development. (2014)
• Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. (2014)
• Gene expression signatures affected by alcohol-induced DNA methylomic deregulation in human embryonic stem cells. (2014)
• Neuronal substrates and functional consequences of prenatal cannabis exposure. (2014)
• Exercise and environment as an intervention for neonatal alcohol effects on hippocampal adult neurogenesis and learning. (2014)
• Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). (2014)
• Epigenetics, microRNA, and addiction. (2014)
• Clonal evolution in hematological malignancies and therapeutic implications. (2014)
• Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
• EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014)
• Temporal specification and bilaterality of human neocortical topographic gene expression. (2014)
• MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells. (2014)
• Live imaging-based model selection reveals periodic regulation of the stochastic G1/S phase transition in vertebrate axial development. (2014)
• Mosaic epigenetic dysregulation of ectodermal cells in autism spectrum disorder. (2014)
• Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? (2014)
• Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in β-endorphin-producing POMC neurons of the hypothalamus. (2013)
• Global epigenomic reconfiguration during mammalian brain development. (2013)
• Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure. (2013)
• Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer. (2013)
• Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure. (2013)
• Ewing sarcoma protein: a key player in human cancer. (2013)
• Alcohol metabolism and epigenetics changes. (2013)
• The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. (2013)
• Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. (2013)
• Vitamin D nutrition in pregnancy: current opinion. (2013)
• Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (2013)
• Identification and characterization of the miRNA transcriptome of Ovis aries. (2013)
• DNA methylation program in developing hippocampus and its alteration by alcohol. (2013)
• Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders. (2013)
• Commonality in Down and fetal alcohol syndromes. (2013)
• Gene expression in the human brain: the current state of the study of specificity and spatiotemporal dynamics. (2013)
• Hand in glove: brain and skull in development and dysmorphogenesis. (2013)
• Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. (2013)
• Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation. (2013)
• Suppression and epigenetic regulation of MiR-9 contributes to ethanol teratology: evidence from zebrafish and murine fetal neural stem cell models. (2013)
• Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. (2013)
• Epigenetic medicine and fetal alcohol spectrum disorders. (2013)
• Alcohol exposure during development: Impact on the epigenome. (2013)
• Reduced expression of brain cannabinoid receptor 1 (Cnr1) is coupled with an increased complementary micro-RNA (miR-26b) in a mouse model of fetal alcohol spectrum disorders. (2013)
• Effects of Ethanol Exposure during Distinct Periods of Brain Development on Hippocampal Synaptic Plasticity. (2013)
• 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. (2012)
• Cannabinoid receptor 1 signaling in embryo neurodevelopment. (2012)
• Choline supplementation mitigates trace, but not delay, eyeblink conditioning deficits in rats exposed to alcohol during development. (2012)
• The Aplnr GPCR regulates myocardial progenitor development via a novel cell-non-autonomous, Gα(i/o) protein-independent pathway. (2012)
• Housing in environmental complexity following wheel running augments survival of newly generated hippocampal neurons in a rat model of binge alcohol exposure during the third trimester equivalent. (2012)
• Enhanced deficits in long-term potentiation in the adult dentate gyrus with 2nd trimester ethanol consumption. (2012)
• Alcohol alters DNA methylation patterns and inhibits neural stem cell differentiation. (2011)
• A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories. (2011)
• Functional consequences of developmentally regulated alternative splicing. (2011)
• Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls. (2011)
• Effects of ethanol and NAP on cerebellar expression of the neural cell adhesion molecule L1. (2011)
• Down syndrome: searching for the genetic culprits. (2011)
• Mechanisms and consequences of alternative polyadenylation. (2011)
• MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. (2011)
• Molecular mechanisms of long noncoding RNAs. (2011)
• Uncovering genomic causes of co-morbidity in epilepsy: gene-driven phenotypic characterization of rare microdeletions. (2011)
• Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord. (2011)
• Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome. (2010)
• Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats. (2010)
• Normal development of brain circuits. (2010)
• Craniofacial birth defects: The role of neural crest cells in the etiology and pathogenesis of Treacher Collins syndrome and the potential for prevention. (2010)
• Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. (2010)
• MicroRNAs: master regulators of ethanol abuse and toxicity? (2010)
• Genetic and epigenetic insights into fetal alcohol spectrum disorders. (2010)
• Fetal alcohol spectrum disorders: from research to policy. (2010)
• Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells. (2010)
• Prenatal alcohol exposure reduces the proportion of newly produced neurons and glia in the dentate gyrus of the hippocampus in female rats. (2010)
• Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking. (2010)
• Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. (2010)
• Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
• Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation. (2009)
• Down syndrome--recent progress and future prospects. (2009)
• Sonic hedgehog ligand partners with caveolin-1 for intracellular transport. (2009)
• The future of genetics in psychology and psychiatry: microarrays, genome-wide association, and non-coding RNA. (2009)
• Neurotoxic effects and biomarkers of lead exposure: a review. (2009)
• Response inhibition among early adolescents prenatally exposed to tobacco: an fMRI study. (2009)
• Neuroimaging of children following prenatal drug exposure. (2009)
• Effects of prenatal methamphetamine exposure on verbal memory revealed with functional magnetic resonance imaging. (2009)
• Modeling the impact of alcohol on cortical development in a dish: strategies from mapping neural stem cell fate. (2008)
• Ethanol consumption during early pregnancy alters the disposition of tangentially migrating GABAergic interneurons in the fetal cortex. (2008)
• Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
• Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling. (2008)
• Association study of Wnt signaling pathway genes in bipolar disorder. (2008)
• Model-based analysis of ChIP-Seq (MACS). (2008)
• Model-based analysis of ChIP-Seq (MACS). (2008)
• Pubertal hormones modulate the addition of new cells to sexually dimorphic brain regions. (2008)
• The role of cytoplasmic serine residues of the cell adhesion molecule L1 in neurite outgrowth, endocytosis, and cell migration. (2007)
• Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. (2007)
• Mechanisms for persistent microphthalmia following ethanol exposure during retinal neurogenesis in zebrafish embryos. (2007)
• Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes. (2007)
• Perlecan controls neurogenesis in the developing telencephalon. (2007)
• Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex. (2007)
• Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. (2007)
• PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. (2007)
• The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. (2007)
• Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. (2007)
• Origin of oligodendrocytes in the subventricular zone of the adult brain. (2006)
• Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. (2005)
• Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes. (2004)
• Structural abnormalities in the brains of human subjects who use methamphetamine. (2004)
• Cannabinoid receptor, CB1, expression follows neuronal differentiation in the early chick embryo. (2004)
• Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. (2003)
• Relationship between availability of NMDA receptor subunits and their expression at the synapse. (2002)
• Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death. (2002)
• Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner. (2001)
• In utero cocaine-induced dysfunction of dopamine D1 receptor signaling and abnormal differentiation of cerebral cortical neurons. (2000)
• Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter/enhancer. (2000)
• Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. (1995)

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