complex diseases phenotype
Evidence from:
primary |
all sources
Related entities (38)
Mentioned in (70)
Papers in which this entity is mentioned.
- Associations between common genetic variants and income provide insights about the socio-economic health gradient. (2025)
- Genome-wide association testing beyond SNPs. (2025)
- Yield of genetic association signals from genomes, exomes and imputation in the UK Biobank. (2024)
- Principles and methods for transferring polygenic risk scores across global populations. (2024)
- Recent advances in polygenic scores: translation, equitability, methods and FAIR tools. (2024)
- Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases. (2024)
- An overview of DNA methylation-derived trait score methods and applications. (2023)
- Pruning and thresholding approach for methylation risk scores in multi-ancestry populations. (2023)
- A saturated map of common genetic variants associated with human height. (2022)
- Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease. (2022)
- Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. (2022)
- Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. (2021)
- Genotypes of informative loci from 1000 Genomes data allude evolution and mixing of human populations. (2021)
- The mutational constraint spectrum quantified from variation in 141,456 humans. (2020)
- Polygenic prediction via Bayesian regression and continuous shrinkage priors. (2019)
- The mutational constraint spectrum quantified from variation in 141,456 humans (2019)
- Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis. (2019)
- The GenomeAsia 100K Project enables genetic discoveries across Asia. (2019)
- Designing combination therapies with modeling chaperoned machine learning. (2019)
- What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics. (2018)
- Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. (2018)
- The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). (2017)
- The impact of structural variation on human gene expression. (2017)
- LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. (2017)
- Enacting the molecular imperative: How gene-environment interaction research links bodies and environments in the post-genomic age. (2016)
- A gene-based association method for mapping traits using reference transcriptome data. (2015)
- HLAreporter: a tool for HLA typing from next generation sequencing data. (2015)
- A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants. (2015)
- SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations. (2015)
- Guidelines for investigating causality of sequence variants in human disease. (2014)
- Transcriptome sequencing of a large human family identifies the impact of rare noncoding variants. (2014)
- DNA methylation signatures link prenatal famine exposure to growth and metabolism. (2014)
- A general approach for haplotype phasing across the full spectrum of relatedness. (2014)
- Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity. (2013)
- Structure and function of complex brain networks. (2013)
- The Growing Importance of CNVs: New Insights for Detection and Clinical Interpretation. (2013)
- Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. (2013)
- Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report. (2013)
- Associations between maternal genotypes and metabolites implicated in congenital heart defects. (2012)
- CNVs: harbingers of a rare variant revolution in psychiatric genetics. (2012)
- Annotation of functional variation in personal genomes using RegulomeDB. (2012)
- Pathway analysis of genomic data: concepts, methods, and prospects for future development. (2012)
- DELLY: structural variant discovery by integrated paired-end and split-read analysis. (2012)
- An integrated encyclopedia of DNA elements in the human genome. (2012)
- Meta-analysis and genome-wide interpretation of genetic susceptibility to drug addiction. (2011)
- Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011)
- A framework for variation discovery and genotyping using next-generation DNA sequencing data. (2011)
- Gene set analysis of genome-wide association studies: methodological issues and perspectives. (2011)
- Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. (2011)
- The PhenX Toolkit: get the most from your measures. (2011)
- LocusZoom: regional visualization of genome-wide association scan results. (2010)
- Genetics of psychiatric disorders methods: molecular approaches. (2010)
- Statistical analysis strategies for association studies involving rare variants. (2010)
- Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes. (2010)
- Large copy-number variations are enriched in cases with moderate to extreme obesity. (2010)
- i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study. (2010)
- Genetics and beyond--the transcriptome of human monocytes and disease susceptibility. (2010)
- A groupwise association test for rare mutations using a weighted sum statistic. (2009)
- Meta-analysis in genome-wide association studies. (2009)
- Finding the missing heritability of complex diseases. (2009)
- Genomewide association studies: history, rationale, and prospects for psychiatric disorders. (2009)
- Marker selection for genetic case-control association studies. (2009)
- Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. (2009)
- Genome-wide association study of alcohol dependence. (2009)
- The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. (2007)
- FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization. (2006)
- SNPs3D: candidate gene and SNP selection for association studies. (2006)
- Why most published research findings are false. (2005)
Merged raw entities (9)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| complex diseases | phenotype | 28 | 35 |
| complex disease | phenotype | 22 | 32 |
| common diseases | phenotype | 19 | 23 |
| common disease | phenotype | 9 | 10 |
| common complex disease | phenotype | 3 | 3 |
| common complex diseases | phenotype | 3 | 3 |
| complex human diseases | phenotype | 3 | 3 |
| common variant common disease scenario | phenotype | — | — |
| complex disease liability loci | phenotype | — | — |