mental retardation phenotype
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Related entities (35)
Mentioned in (174)
Papers in which this entity is mentioned.
- Predicting Fetal Alcohol Spectrum Disorders Using Machine Learning Techniques: Multisite Retrospective Cohort Study. (2023)
- Racial/Ethnic Disparity in Association Between Fetal Alcohol Syndrome and Alcohol Intake During Pregnancy: Multisite Retrospective Cohort Study. (2023)
- Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice. (2021)
- Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia. (2020)
- Reduced Hippocampal Volumes Partially Mediate Effects of Prenatal Alcohol Exposure on Spatial Navigation on a Virtual Water Maze Task in Children. (2020)
- Neuroanatomical Changes Underlying Vertical HIV Infection in Adolescents. (2019)
- Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders. (2019)
- Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity. (2018)
- The Gene Encoding Protocadherin 9 (PCDH9), a Novel Risk Factor for Major Depressive Disorder. (2018)
- The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer. (2018)
- Imaging structural and functional brain development in early childhood. (2018)
- Meta-Analyses of Externalizing Disorders: Genetics or Prenatal Alcohol Exposure? (2018)
- Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. (2018)
- Neurotrophins in the Brain: Interaction With Alcohol Exposure During Development. (2017)
- Cortical gyrification is abnormal in children with prenatal alcohol exposure. (2017)
- Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. (2017)
- Genome-wide association analysis identifies common variants influencing infant brain volumes. (2017)
- Mapping and phasing of structural variation in patient genomes using nanopore sequencing. (2017)
- Epigenetic profiling of ADHD symptoms trajectories: a prospective, methylome-wide study. (2017)
- Relationships between Head Circumference, Brain Volume and Cognition in Children with Prenatal Alcohol Exposure. (2016)
- Inhibition of Mammary Cancer Progression in Fetal Alcohol Exposed Rats by β-Endorphin Neurons. (2016)
- The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository. (2016)
- Prenatal Exposure to Arsenic Impairs Behavioral Flexibility and Cortical Structure in Mice. (2016)
- The placenta and neurodevelopment: sex differences in prenatal vulnerability. (2016)
- Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants. (2016)
- Verbal learning and memory impairment in children with fetal alcohol spectrum disorders. (2015)
- Trace elements as paradigms of developmental neurotoxicants: Lead, methylmercury and arsenic. (2015)
- Pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. (2015)
- Child psychiatry branch of the National Institute of Mental Health longitudinal structural magnetic resonance imaging study of human brain development. (2015)
- Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS. (2015)
- The effects of age, sex, and hormones on emotional conflict-related brain response during adolescence. (2015)
- Acceptability of a computerized brief intervention for alcohol among abstinent but at-risk pregnant women. (2015)
- MiR-125b protects against ethanol-induced apoptosis in neural crest cells and mouse embryos by targeting Bak 1 and PUMA. (2015)
- The Effects of Arsenic Exposure on Neurological and Cognitive Dysfunction in Human and Rodent Studies: A Review. (2014)
- The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. (2014)
- Modelling cognitive affective biases in major depressive disorder using rodents. (2014)
- Heritability and genomics of gene expression in peripheral blood. (2014)
- White matter integrity in alcohol-naive youth with a family history of alcohol use disorders. (2014)
- Diminishing return for increased Mappability with longer sequencing reads: implications of the k-mer distributions in the human genome. (2014)
- Renal dysfunction in fetal alcohol syndrome: a potential contributor on developmental disabilities of offspring. (2014)
- Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in β-endorphin-producing POMC neurons of the hypothalamus. (2013)
- Fate analysis of adult hippocampal progenitors in a murine model of fetal alcohol spectrum disorder (FASD). (2013)
- Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. (2013)
- Mitogen-activated protein kinase modulates ethanol inhibition of cell adhesion mediated by the L1 neural cell adhesion molecule. (2013)
- White matter microstructure abnormalities and executive function in adolescents with prenatal cocaine exposure. (2013)
- A genetic perspective on the proposed inclusion of cannabis withdrawal in DSM-5. (2013)
- Diffusion MRI of the developing cerebral cortical gray matter can be used to detect abnormalities in tissue microstructure associated with fetal ethanol exposure. (2013)
- Clinical whole-exome sequencing for the diagnosis of mendelian disorders. (2013)
- Prenatal ethanol exposure disrupts intraneocortical circuitry, cortical gene expression, and behavior in a mouse model of FASD. (2013)
- In utero alcohol exposure, epigenetic changes, and their consequences. (2013)
- The feasibility and cost of neonatal screening for prenatal alcohol exposure by measuring phosphatidylethanol in dried blood spots. (2013)
- The role of nutrition in children's neurocognitive development, from pregnancy through childhood. (2013)
- Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders. (2013)
- Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. (2013)
- Perinatal exposure to alcohol: implications for lung development and disease. (2013)
- Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model. (2013)
- Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brain. (2013)
- Brief FASD prevention intervention: physicians' skills demonstrated in a clinical trial in Russia. (2013)
- Neuroprotective actions of perinatal choline nutrition. (2013)
- Zebrafish models of human liver development and disease. (2013)
- Effects of Ethanol Exposure during Distinct Periods of Brain Development on Hippocampal Synaptic Plasticity. (2013)
- Over-expression of Nrf2 diminishes ethanol-induced oxidative stress and apoptosis in neural crest cells by inducing an antioxidant response. (2013)
- Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. (2012)
- Early exposure to alcohol leads to permanent impairment of dendritic excitability in neocortical pyramidal neurons. (2012)
- Persistent dose-dependent changes in brain structure in young adults with low-to-moderate alcohol exposure in utero. (2012)
- Auditory brainstem response (ABR) abnormalities across the life span of rats prenatally exposed to alcohol. (2012)
- How to measure cortical folding from MR images: a step-by-step tutorial to compute local gyrification index. (2012)
- Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders. (2012)
- Epilepsy genetics--past, present, and future. (2011)
- Teratogenic effects of thalidomide: molecular mechanisms. (2011)
- Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease. (2011)
- Fetal alcohol spectrum disorders: neuropsychological and behavioral features. (2011)
- Candidate placental biomarkers for intrauterine alcohol exposure. (2011)
- Classification of neurocognitive disorders in DSM-5: a work in progress. (2011)
- Functional consequences of developmentally regulated alternative splicing. (2011)
- Cranial neural crest cells on the move: their roles in craniofacial development. (2011)
- The role of DYRK1A in neurodegenerative diseases. (2011)
- Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum. (2011)
- Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. (2011)
- Brain imaging correlates of verbal working memory in children following traumatic brain injury. (2011)
- Ventromedian forebrain dysgenesis follows early prenatal ethanol exposure in mice. (2011)
- Heritability of delay discounting in adolescence: a longitudinal twin study. (2011)
- Basal forebrain involvement in low-functioning autistic children: a voxel-based morphometry study. (2011)
- Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. (2011)
- Tissue plasminogen activator is required for the development of fetal alcohol syndrome in mice. (2011)
- S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors. (2011)
- Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions. (2011)
- Sex differences in adolescent white matter architecture. (2011)
- Risk factors for behavioural problems in foetal alcohol spectrum disorders. (2011)
- Prenatal alcohol exposure: fetal programming and later life vulnerability to stress, depression and anxiety disorders. (2010)
- Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome. (2010)
- A 14-year retrospective maternal report of alcohol consumption in pregnancy predicts pregnancy and teen outcomes. (2010)
- "CRASH"ing with the worm: insights into L1CAM functions and mechanisms. (2010)
- Toward a neurobehavioral profile of fetal alcohol spectrum disorders. (2010)
- A syndrome of short stature, microcephaly and speech delay is associated with duplications reciprocal to the common Sotos syndrome deletion. (2010)
- Normal development of brain circuits. (2010)
- Craniofacial birth defects: The role of neural crest cells in the etiology and pathogenesis of Treacher Collins syndrome and the potential for prevention. (2010)
- Histone methylation regulates memory formation. (2010)
- MicroRNAs: master regulators of ethanol abuse and toxicity? (2010)
- Longitudinal characterization of white matter maturation during adolescence. (2010)
- Assessment of benefits of a universal screen for maternal alcohol use during pregnancy. (2010)
- Structural MRI of pediatric brain development: what have we learned and where are we going? (2010)
- The contributions of disease and genetic factors towards regional cortical thinning in schizophrenia: the UCLA family study. (2010)
- Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells. (2010)
- Neurocognitive correlates of white matter quality in adolescent substance users. (2010)
- The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. (2010)
- The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos. (2010)
- Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 7. (2010)
- Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model. (2010)
- Zebrafish fetal alcohol syndrome model: effects of ethanol are rescued by retinoic acid supplement. (2010)
- Reduced cortical folding in mental retardation. (2010)
- Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome. (2009)
- Phosphodiesterase inhibition increases CREB phosphorylation and restores orientation selectivity in a model of fetal alcohol spectrum disorders. (2009)
- A genome-wide association study of autism reveals a common novel risk locus at 5p14.1. (2009)
- Ethanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60(src). (2009)
- Alterations in phosphorylated cyclic adenosine monophosphate response element of binding protein activity: a pathway for fetal alcohol syndrome-related neurotoxicity. (2009)
- A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. (2009)
- On the value of homogeneous constructs for construct validation, theory testing, and the description of psychopathology. (2009)
- Genomewide association studies: history, rationale, and prospects for psychiatric disorders. (2009)
- Insulin-like growth factor-I mitigates motor coordination deficits associated with neonatal alcohol exposure in rats. (2009)
- Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation. (2009)
- Novel SOX2 mutations and genotype-phenotype correlation in anophthalmia and microphthalmia. (2009)
- Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum. (2009)
- Neurotoxic effects and biomarkers of lead exposure: a review. (2009)
- Prenatal NAP+SAL prevents developmental delay in a mouse model of Down syndrome through effects on N-methyl-D-aspartic acid and gamma-aminobutyric acid receptors. (2009)
- Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept. (2009)
- Alcohol consumption by women before and during pregnancy. (2009)
- Do multivitamin supplements modify the relationship between prenatal alcohol intake and miscarriage? (2009)
- Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8. (2009)
- An alcohol binding site on the neural cell adhesion molecule L1. (2008)
- Modeling the impact of alcohol on cortical development in a dish: strategies from mapping neural stem cell fate. (2008)
- Neuropsychological study of FASD in a sample of American Indian children: processing simple versus complex information. (2008)
- Fetal alcohol spectrum disorders and their persisting sequelae in adult life. (2008)
- Mapping white matter integrity and neurobehavioral correlates in children with fetal alcohol spectrum disorders. (2008)
- Children with heavy prenatal alcohol exposure demonstrate deficits on multiple measures of concept formation. (2008)
- Cannabis withdrawal in the United States: results from NESARC. (2008)
- Prenatal alcohol exposure increases vulnerability to stress and anxiety-like disorders in adulthood. (2008)
- Differences in executive functioning in children with heavy prenatal alcohol exposure or attention-deficit/hyperactivity disorder. (2008)
- Fetal alcohol syndrome (FAS) in C57BL/6 mice detected through proteomics screening of the amniotic fluid. (2008)
- Automated diagnosis of fetal alcohol syndrome using 3D facial image analysis. (2008)
- The power of comparative and developmental studies for mouse models of Down syndrome. (2007)
- Genetic and environmental factors in complex neurodevelopmental disorders. (2007)
- Transcriptional regulation of cortical interneuron development. (2007)
- Characterization of Potocki-Lupski syndrome (dup(17)(p11.2p11.2)) and delineation of a dosage-sensitive critical interval that can convey an autism phenotype. (2007)
- PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. (2007)
- Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. (2007)
- Holoprosencephaly. (2007)
- Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans. (2006)
- Restoration of neuronal plasticity by a phosphodiesterase type 1 inhibitor in a model of fetal alcohol exposure. (2006)
- Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice. (2006)
- Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brain. (2006)
- Diffusion tensor imaging in children with fetal alcohol spectrum disorders. (2006)
- Impaired neural networks for approximate calculation in dyscalculic children: a functional MRI study. (2006)
- Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly. (2005)
- Brief intervention for prenatal alcohol use: a randomized trial. (2005)
- Genomic disorders: molecular mechanisms for rearrangements and conveyed phenotypes. (2005)
- Genetic contributions to human gyrification: sulcal morphometry in Williams syndrome. (2005)
- Neonatal alcohol exposure induces long-lasting impairment of visual cortical plasticity in ferrets. (2003)
- Effects of prenatal alcohol exposure on child development. (2002)
- Functional brain activation during arithmetic processing in females with fragile X Syndrome is related to FMR1 protein expression. (2002)
- Mechanisms of alcohol-induced damage to the developing nervous system. (2001)
- Modeling alcohol's effects on organs in animal models. (2000)
- Role of founder cell deficit and delayed neuronogenesis in microencephaly of the trisomy 16 mouse. (2000)
- Drinking moderately and pregnancy. Effects on child development. (1999)
- Biochemical and morphometric analyses show that myelination in the insulin-like growth factor 1 null brain is proportionate to its neuronal composition. (1998)
- The hormonal effects of alcohol use on the mother and fetus. (1998)
- Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome. (1998)
- Alcohol inhibits cell-cell adhesion mediated by human L1. (1996)
- Clinical Recognition of FAS: Difficulties of Detection and Diagnosis. (1994)
- Prenatal Alcohol Exposure and Neurobehavioral Development: Where Is the Threshold? (1994)
- Critical Periods for Prenatal Alcohol Exposure: Evidence From Animal and Human Studies. (1994)
- A Long-Term Perspective of FAS. (1994)
- Alcohol-related birth defects: an update. (1988)
- Clinical profile and prevalence of fetal alcohol syndrome in an isolated community in British Columbia. (1987)
Merged raw entities (9)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| mental retardation | phenotype | 159 | 272 |
| psychomotor retardation | phenotype | 7 | 9 |
| severe mental retardation | phenotype | 5 | 5 |
| mild mental retardation | phenotype | 4 | 6 |
| x-linked mental retardation | phenotype | 4 | 10 |
| mr | phenotype | 3 | 12 |
| severe mr | phenotype | 1 | 1 |
| xlmr | phenotype | 1 | 8 |
| mild mr | phenotype | — | — |