risk allele cohort

Aliases: independent risk variant, individual risk alleles, risk allele, risk allele score, risk alleles, risk genotype, risk variant, risk variants, significant risk allele

Evidence from: primary | all sources

Related entities (29)

Subject	Relation	Object	p-value	Evidence
European population	associated_with	risk allele	—	1
patients	associated_with	risk allele	—	1
risk allele	associated_with	1000 Genomes Project	—	1
risk allele	associated_with	5-HTT	—	1
risk allele	associated_with	alcohol	—	1
risk allele	risk_factor_for	alcohol dependence	0.027	1
risk allele	risk_factor_for	Alzheimer's disease	—	1
risk allele	risk_factor_for	AP	—	1
risk allele	risk_factor_for	BiP	—	1
risk allele	risk_factor_for	bipolar disorder	—	1
risk allele	risk_factor_for	bladder cancer	—	1
risk allele	risk_factor_for	BMI	—	1
risk allele	associated_with	disease	—	1
risk allele	risk_factor_for	disease	—	2
risk allele	risk_factor_for	disease risk	—	1
risk allele	risk_factor_for	drug dependence	—	1
risk allele	associated_with	EEG	—	1
risk allele	associated_with	eQTLGen Consortium	—	1
risk allele	associated_with	ERP	—	1
risk allele	associated_with	Htr2a	—	1
risk allele	risk_factor_for	mood disorders	—	1
risk allele	risk_factor_for	neuropsychiatric disorders	—	1
risk allele	risk_factor_for	PAU	—	2
risk allele	risk_factor_for	relapse	—	1
risk allele	risk_factor_for	schizophrenia	—	1
risk allele	risk_factor_for	SCZ	—	1
risk allele	risk_factor_for	smoking cessation	—	1
risk allele	risk_factor_for	substance use	—	1
study cohort	associated_with	risk allele	—	1

Mentioned in (38)

Papers in which this entity is mentioned.

Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis. (2026)
Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. (2025)
Detection and analysis of complex structural variation in human genomes across populations and in brains of donors with psychiatric disorders. (2024)
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. (2023)
The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum. (2022)
Research Review: A guide to computing and implementing polygenic scores in developmental research. (2022)
Shared genetic architecture across psychiatric disorders. (2021)
Genetics of substance use disorders in the era of big data. (2021)
Polygenic risk scores: from research tools to clinical instruments. (2020)
Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks. (2020)
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020)
Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders. (2019)
Epigenetics and depression . (2019)
Translating genome-wide association findings into new therapeutics for psychiatry. (2016)
Dissecting ancestry genomic background in substance dependence genome-wide association studies. (2015)
Genomic influences on alcohol problems in a population-based sample of young adults. (2015)
Is the gene-environment interaction paradigm relevant to genome-wide studies? The case of education and body mass index. (2014)
Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. (2014)
Polygenic risk scores for smoking: predictors for alcohol and cannabis use? (2014)
Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. (2013)
DNA methylation contributes to natural human variation. (2013)
Predictors of relapse in a bupropion trial for smoking cessation in recently-abstinent alcoholics: preliminary results using an aggregate genetic risk score. (2012)
The genetics of alcohol dependence: advancing towards systems-based approaches. (2012)
CNVs: harbingers of a rare variant revolution in psychiatric genetics. (2012)
The neuroscience of suicidal behaviors: what can we expect from endophenotype strategies? (2011)
Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants. (2011)
The neuronal transporter gene SLC6A15 confers risk to major depression. (2011)
From genotype to EEG endophenotype: a route for post-genomic understanding of complex psychiatric disease? (2010)
Using public control genotype data to increase power and decrease cost of case-control genetic association studies. (2010)
Genome-wide association studies in diverse populations. (2010)
The genetic interpretation of area under the ROC curve in genomic profiling. (2010)
Finding the missing heritability of complex diseases. (2009)
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. (2009)
Genomewide association studies: history, rationale, and prospects for psychiatric disorders. (2009)
Genomewide association studies and human disease. (2009)
The possible influence of impulsivity and dietary restraint on associations between serotonin genes and binge eating. (2009)
A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. (2009)
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. (2008)

Merged raw entities (13)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
risk allele	variant	18	18
risk variants	variant	10	13
risk alleles	variant	8	9
risk variant	variant	8	10
independent risk variant	cohort	—	—
individual risk alleles	cohort	—	—
risk allele	cohort	—	—
risk alleles	cohort	—	—
risk allele score	cohort	—	—
risk genotype	cohort	—	—
risk variant	cohort	—	—
risk variants	cohort	—	—
significant risk allele	cohort	—	—