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Bierut, Laura

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA

TitleYearPMID
Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. preprint 2025 39974067
High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk. 2022 36324664
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. 2022 36207451
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. 2020 30617275
Sibling comparisons elucidate the associations between educational attainment polygenic scores and alcohol, nicotine and cannabis. 2020 31659820
A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults. 2019 31141183
Development of Alcohol Use Disorder as a Function of Age, Severity, and Comorbidity with Externalizing and Internalizing Disorders in a Young Adult Cohort. 2019 31853508
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. 2019 30679032
The etiology of DSM-5 alcohol use disorder: Evidence of shared and non-shared additive genetic effects. 2019 31229702
Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample. 2015 25486392
Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. 2014 24962325
Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory. 2014 24828478
Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6). 2014 24033696
Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence. 2014 24057674
Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy. 2014 24675634
A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks. 2013 23743675
Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. 2013 23963516
How phenotype and developmental stage affect the genes we find: GABRA2 and impulsivity. 2013 23561058
Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective. 2012 22261179
Effects of child maltreatment and inherited liability on antisocial development: an official records study. 2010 20410725
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