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Kreek, Mary Jeanne

Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, NY, USA

TitleYearPMID
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. 2022 36207451
Population-specific genetic background for the OPRM1 variant rs1799971 (118A>G): implications for genomic medicine and functional analysis. 2021 33037305
Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. 2016 26392368
Individual differences in gene expression of vasopressin, D2 receptor, POMC and orexin: vulnerability to relapse to heroin-seeking in rats. 2015 25446223
Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry. 2015 26384852
Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective. 2012 22261179
Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics. 2012 23023708
The genetics of the opioid system and specific drug addictions. 2012 22547174
Effects of adrenal sensitivity, stress- and cue-induced craving, and anxiety on subsequent alcohol relapse and treatment outcomes. 2011 21536969
Haplotype block structure of the genomic region of the mu opioid receptor gene. 2011 21160491
Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts. 2010 20237803
Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. 2010 20520587
Increased OPRM1 DNA methylation in lymphocytes of methadone-maintained former heroin addicts. 2009 18650805
Prodynorphin gene promoter repeat associated with cocaine/alcohol codependence. 2007 17559549
Stress, dysregulation of drug reward pathways, and the transition to drug dependence. 2007 17671276
The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor. 2007 17877633
Association analysis of polymorphisms in serotonin 1B receptor (HTR1B) gene with heroin addiction: a comparison of molecular and statistically estimated haplotypes. 2006 16344719
Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes. 2006 16520439
Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction. 2005 16251987
Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. 2005 15525999
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