Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication.
- Authors
- Kessler, Ronald C; Berglund, Patricia; Demler, Olga; Jin, Robert; Merikangas, Kathleen R; Walters, Ellen E
- Year
- 2005
- Journal
- Archives of general psychiatry
- PMID
- 15939837
- DOI
- 10.1001/archpsyc.62.6.593
CONTEXT: Little is known about lifetime prevalence or age of onset of DSM-IV disorders. OBJECTIVE: To estimate lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the recently completed National Comorbidity Survey Replication. DESIGN AND SETTING: Nationally representative face-to-face household survey conducted between February 2001 and April 2003 using the fully structured World Health Organization World Mental Health Survey version of the Composite International Diagnostic Interview. PARTICIPANTS: Nine thousand two hundred eighty-two English-speaking respondents aged 18 years and older. MAIN OUTCOME MEASURES: Lifetime DSM-IV anxiety, mood, impulse-control, and substance use disorders. RESULTS: Lifetime prevalence estimates are as follows: anxiety disorders, 28.8%; mood disorders, 20.8%; impulse-control disorders, 24.8%; substance use disorders, 14.6%; any disorder, 46.4%. Median age of onset is much earlier for anxiety (11 years) and impulse-control (11 years) disorders than for substance use (20 years) and mood (30 years) disorders. Half of all lifetime cases start by age 14 years and three fourths by age 24 years. Later onsets are mostly of comorbid conditions, with estimated lifetime risk of any disorder at age 75 years (50.8%) only slightly higher than observed lifetime prevalence (46.4%). Lifetime prevalence estimates are higher in recent cohorts than in earlier cohorts and have fairly stable intercohort differences across the life course that vary in substantively plausible ways among sociodemographic subgroups. CONCLUSIONS: About half of Americans will meet the criteria for a DSM-IV disorder sometime in their life, with first onset usually in childhood or adolescence. Interventions aimed at prevention or early treatment need to focus on youth.
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| Research progress on the neural circuits mechanisms of anxiety. | Gong W | β | 2025 | β |
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| The association between depressive symptoms and overweight or obesity in prepubertal children: Findings from the QUALITY cohort. | Bonin S et al. | β | 2024 | β |
| The auditory stimulus facilitates memory guidance in distractor suppression in males with substance use disorder. | Cai B et al. | β | 2024 | β |
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| The Effectiveness of Preventative Interventions to Reduce Mental Health Problems in at-risk Children and Young People: A Systematic Review of Reviews. | McGovern R et al. | β | 2024 | β |
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| The Impact of User Engagement With Exposure Components on Posttraumatic Stress Symptoms in an mHealth Mobile App: Secondary Analysis of a Randomized Controlled Trial. | Davis CA et al. | β | 2024 | β |
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| 'The Lost Peace': Evidencing the Syndemic Relationship between Neglected Tropical Diseases and Mental Distress in Liberia. | McCollum R et al. | β | 2024 | β |
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| The Social Return on Investment in programs designed for young people living with a family member who experiences mental health challenges: study protocol. | Reupert AE et al. | β | 2024 | β |
| The Transition from Childhood to Adolescence: Between Health and Vulnerability. | Mastorci F et al. | β | 2024 | β |
| The use of online methods to recruit and follow a hard-to-reach population in the Peer Alternatives for Addiction Study 2021 Cohort. | Zemore SE et al. | β | 2024 | β |
| Toward a mechanistic understanding of the role of error monitoring and memory in social anxiety. | Hosseini K et al. | β | 2024 | β |
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| Treatment of Obsessive-Compulsive Disorder in Children and Youth: A Meta-Analysis. | Steele DW et al. | β | 2024 | β |
| Trends in incidence of self-harm, neurodevelopmental and mental health conditions among university students compared with the general population: nationwide electronic data linkage study in Wales. | John A et al. | β | 2024 | β |
| Tyrosine Hydroxylase-Positive Nucleus Accumbens Neurons Influence Delay Discounting in a Mouse T-Maze Task. | Appings R et al. | β | 2024 | β |
| Understanding Mechanisms that Maintain Social Anxiety Disorder in Autistic Individuals Through the Clark and Wells (1995) Model and Beyond: A Systematic Review. | Lei J et al. | β | 2024 | β |
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| Urea Level and Depression in Patients with Chronic Kidney Disease. | Levassort H et al. | β | 2024 | β |
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| Using intervention mapping to develop an occupational therapy informed intervention for adolescents experiencing mental health difficulties. | Parsonage-Harrison J et al. | β | 2024 | β |
| Using latent variables to improve the management of depression among hemodialysis patients. | Gunzler DD et al. | β | 2024 | β |
| Validation of the Capacity for the Psychotherapy Process Scale for Use in Adolescent Patients. | Hou Y et al. | β | 2024 | β |
| Validation of visual analog scales of mood and anxiety at the workplace. | Dutheil F et al. | β | 2024 | β |
| Validity and Reliability of the Transcultural Arabic Adaptation of the Food-Mood Questionnaire Among College Students. | Begdache L et al. | β | 2024 | β |
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| World Psychiatric Association-Asian Journal of Psychiatry Commission on Public Mental Health. | Bhugra D et al. | β | 2024 | β |
| Yoga as a therapeutic approach to mental health in university students: a randomized controlled trial. | Castellote-Caballero Y et al. | β | 2024 | β |
| Young adults, particularly young women, account for an increasingly large share of Dutch mental healthcare expenditure over the period between 2015 and 2021. | Dijkstra L et al. | β | 2024 | β |
| Young people's sense of agency and responsibility towards promoting mental health in Brazil: a reflexive thematic analysis. | Mendes JAA et al. | β | 2024 | β |
| Youth Perspectives on 'Highly Personalised and Measurement-Based Care': Qualitative Co-Design of Education Materials. | McKenna S et al. | β | 2024 | β |