Neurogenetic adaptive mechanisms in alcoholism.
- Authors
- Cloninger, C R
- Year
- 1987
- Journal
- Science (New York, N.Y.)
- PMID
- 2882604
- DOI
- 10.1126/science.2882604
Clinical, genetic, and neuropsychopharmacological studies of developmental factors in alcoholism are providing a better understanding of the neurobiological bases of personality and learning. Studies of the adopted-away children of alcoholics show that the predisposition to initiate alcohol-seeking behavior is genetically different from susceptibility to loss of control after drinking begins. Alcohol-seeking behavior is a special case of exploratory appetitive behavior and involves different neurogenetic processes than do susceptibility to behavioral tolerance and dependence on the antianxiety or sedative effects of alcohol. Three dimensions of personality have been described that may reflect individual differences in brain systems modulating the activation, maintenance, and inhibition of behavioral responses to the effects of alcohol and other environmental stimuli. These personality traits distinguish alcoholics with different patterns of behavioral, neurophysiological, and neuropharmacological responses to alcohol.
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| Identification of TNR as a Potential Hippocampal Biomarker of Novelty Seeking Behavior with Integrated Quantitative Proteomics and Systems Genetics Approaches. | Liu J et al. | β | 2025 | β |
| Molecular Effect of Variants in Serotonin Transporter Gene in Women with Alcohol Use Disorder. | Rychel M et al. | β | 2025 | β |
| Profiles of impulsivity and alcohol use: Unveiling personality, cognitive traits, and DSM diagnoses. | Lau C et al. | β | 2025 | β |
| The Promise of Genetics in Alcohol Use Disorders and the Problems of Phenotype, Polygenetic Architecture, Ancestry, and Comorbidity. | Ehlers CL et al. | β | 2025 | β |
| Within-day associations between affect and intentions to drink alcohol in adolescents and young adults: A registered report. | King KM et al. | β | 2025 | β |
| Association patterns of antisocial personality disorder across substance use disorders. | Low A et al. | β | 2024 | β |
| Drinking While Stressed and Drinking to Cope Differentially Relate to Mental Health. | Vornlocher C et al. | β | 2024 | β |
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| OPRM1 Gene Polymorphism in Women with Alcohol Use Disorder. | BoroΕ A et al. | β | 2024 | β |
| Targeting Symptom-Specific Networks With Transcranial Magnetic Stimulation. | Siddiqi SH et al. | β | 2024 | β |
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| Alcohol Use Disorder and Associated Factors Among Elderly in Ethiopia. | Wolde A | β | 2023 | β |
| Exploring associations between affect and marijuana use in everyday life via specification curve analysis. | Dora J et al. | β | 2023 | β |
| Old and New Biomarkers of Alcohol Abuse: Narrative Review. | Fakhari S et al. | β | 2023 | β |
| The daily association between affect and alcohol use: A meta-analysis of individual participant data. | Dora J et al. | β | 2023 | β |
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| Central nervous system monoamine metabolite response to alcohol exposure is associated with future alcohol intake in a nonhuman primate model (Macaca mulatta). | Wood EK et al. | β | 2022 | β |
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| Alcohol-related phenotypes and platelet serotonin concentration. | Nedic Erjavec G et al. | β | 2021 | β |
| Autistic Personality Traits and Treatment Outcome for Alcohol Use Disorders. | Hildebrand KarlΓ©n M et al. | β | 2021 | β |
| Genetically selected alcohol-preferring msP rats to study alcohol use disorder: Anything lost in translation? | Borruto AM et al. | β | 2021 | β |
| Incipient alcohol use in childhood: Early alcohol sipping and its relations with psychopathology and personality. | Watts AL et al. | β | 2021 | β |
| Promising vulnerability markers of substance use and misuse: A review of human neurobehavioral studies. | Lees B et al. | β | 2021 | β |
| Single nucleotide polymorphism heritability and differential patterns of genetic overlap between inattention and four neurocognitive factors in youth. | Micalizzi L et al. | β | 2021 | β |
| Alcohol Use Disorder and Risk of Suicide in a Swedish Population-Based Cohort. | Edwards AC et al. | β | 2020 | β |
| Alcohol Use Disorder Interventions Targeting Brain Sites for Both Conditioned Reward and Delayed Gratification. | Oberlin BG et al. | β | 2020 | β |
| A trait-like propensity to experience internalizing symptoms is associated with problem alcohol involvement across adulthood, but not adolescence. | King KM et al. | β | 2020 | β |
| DSM-5 Maladaptive Personality Domains among Treatment-Seeking Individuals with Alcohol Use Disorder: The Role of Disinhibition and Negative Affectivity. | Cavicchioli M et al. | β | 2020 | β |
| Neonatal temperament and neuromotor differences are predictive of adolescent alcohol intake in rhesus monkeys (Macaca mulatta). | Wood EK et al. | β | 2020 | β |
| Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment? | Jurado-Barba R et al. | β | 2020 | β |
| Predictive factors of long-term follow-up in treatment of Korean alcoholics with naltrexone or acamprosate. | Huh SY et al. | β | 2020 | β |
| Reexamining the Psychometric Properties of the Substance Use Risk Profile Scale. | Blanchard BE et al. | β | 2020 | β |
| The personality profile of chronic alcohol dependent patients with comorbid gambling disorder symptoms. | KovΓ‘cs I et al. | β | 2020 | β |
| Age of onset of substance use in patients with dual diagnosis and its association with clinical characteristics, risk behaviors, course, and outcome: A retrospective study. | Subodh BN et al. | β | 2019 | β |
| Alcohol Use Disorder and Antisocial and Borderline Personality Disorders. | Helle AC et al. | β | 2019 | β |
| Are Some Alcohol Use Disorder Criteria More (or Less) Externalizing than Others? Distinguishing Alcohol Use Symptomatology from General Externalizing Psychopathology. | McDowell YE et al. | β | 2019 | β |
| Blunted stress reactivity reveals vulnerability to early life adversity in young adults with a family history of alcoholism. | Lovallo WR et al. | β | 2019 | β |
| Development of Alcohol Use Disorder as a Function of Age, Severity, and Comorbidity with Externalizing and Internalizing Disorders in a Young Adult Cohort. | Nurnberger JI et al. | β | 2019 | β |
| Effects of Common and Rare Chromosome 4 GABAergic Gene Variation on Alcohol Use and Antisocial Behavior. | Deak JD et al. | β | 2019 | β |
| Evidence for incentive salience sensitization as a pathway to alcohol use disorder. | CofresΓ RU et al. | β | 2019 | β |
| Impact of Genetic Variation on Stress-Related Ethanol Consumption. | Mulligan MK et al. | β | 2019 | β |
| Impulsivities and addictions: a multidimensional integrative framework informing assessment and interventions for substance use disorders. | Vassileva J et al. | β | 2019 | β |
| Little video-gaming in adolescents can be protective, but too much is associated with increased substance use. | Turel O et al. | β | 2019 | β |
| Personality traits and risky behavior among motorcyclists: An exploratory study. | Romero DL et al. | β | 2019 | β |
| The association between <i>HTR1B</i> gene rs13212041 polymorphism and onset of alcohol abuse. | Svob Strac D et al. | β | 2019 | β |
| A Critical Review of Methods and Results in the Search for Genetic Contributors to Alcohol Sensitivity. | Schuckit MA | β | 2018 | β |
| Add-On Memantine Treatment for Bipolar II Disorder Comorbid with Alcohol Dependence: A 12-Week Follow-Up Study. | Lee SY et al. | β | 2018 | β |
| Cerebral dopaminergic and glutamatergic transmission relate to different subjective responses of acute alcohol intake: an in vivo multimodal imaging study. | Leurquin-Sterk G et al. | β | 2018 | β |
| Cloninger's Temperament Dimensions and Longitudinal Alcohol Use in Early Midlife: A Northern Finland Birth Cohort 1966 Study. | Vladimirov D et al. | β | 2018 | β |
| Early childhood parenting and child impulsivity as precursors to aggression, substance use, and risky sexual behavior in adolescence and early adulthood. | Hentges RF et al. | β | 2018 | β |
| Evaluating moderators of beneficial effects of severity-based assignment to substance use treatments in impaired drivers. | Wickens CM et al. | β | 2018 | β |
| Genetic Contribution to Initial and Progressive Alcohol Intake Among Recombinant Inbred Strains of Mice. | Mulligan MK et al. | β | 2018 | β |
| Impulsive dispositions and alcohol: what we know, how we know it, and where to go from here. | Stevens AK et al. | β | 2018 | β |
| Kappa opioid regulation of depressive-like behavior during acute withdrawal and protracted abstinence from ethanol. | Jarman SK et al. | β | 2018 | β |
| Longitudinal and Sex Measurement Invariance of the Affective Neuroscience Personality Scales. | Orri M et al. | β | 2018 | β |
| Neurological and neuropsychological effects of low and moderate prenatal alcohol exposure. | Comasco E et al. | β | 2018 | β |
| Personality as an intermediate phenotype for genetic dissection of alcohol use disorder. | Oreland L et al. | β | 2018 | β |
| Positive and negative effects of internalizing on alcohol use problems from childhood to young adulthood: The mediating and suppressing role of externalizing. | Foster KT et al. | β | 2018 | β |
| Risk profiles of personality traits for suicidality among mood disorder patients and community controls. | Su MH et al. | β | 2018 | β |
| The gender risk-severity paradox for alcohol use disorder from adolescence through young adulthood. | Foster KT et al. | β | 2018 | β |
| Trait Impulsivity in Alcohol-naΓ―ve Offspring at High Risk for Alcoholism. | Kumar R et al. | β | 2018 | β |
| Addictions Neuroclinical Assessment: A reverse translational approach. | Kwako LE et al. | β | 2017 | β |
| Age of Drinking Initiation as a Risk Factor for Alcohol Use Disorder Symptoms is Moderated by ALDH2*2 and Ethnicity. | Luczak SE et al. | β | 2017 | β |
| Associations among impulsivity, trauma history, and alcohol misuse within a young adult sample. | Bountress K et al. | β | 2017 | β |
| Associations between early internalizing symptoms and speed of transition through stages of alcohol involvement. | Menary KR et al. | β | 2017 | β |
| Corticotropin Releasing Factor in the Bed Nucleus of the Stria Terminalis in Socially Defeated and Non-stressed Mice with a History of Chronic Alcohol Intake. | Albrechet-Souza L et al. | β | 2017 | β |
| Excess social media use in normal populations is associated with amygdala-striatal but not with prefrontal morphology. | He Q et al. | β | 2017 | β |
| Gambling disorder: Association between duration of illness, clinical, and neurocognitive variables. | Medeiros GC et al. | β | 2017 | β |
| Latent classes of alcohol problems in Mauritian men: Results from the Joint Child Health Project. | Luczak SE et al. | β | 2017 | β |
| Measuring heightened attention to alcohol in a naturalistic setting: A validation study. | Monem RG et al. | β | 2017 | β |
| No Reliable Evidence That Emotional Disorders Are Proximal Antecedents, Concomitants, or Short-Term Consequences of First Episode Alcohol Use Disorders in a Representative Community Sample. | Farmer RF et al. | β | 2017 | β |
| Novelty seeking and reward dependence-related large-scale brain networks functional connectivity variation during salience expectancy. | Li S et al. | β | 2017 | β |
| OPRM1 genotype interacts with serotonin system dysfunction to predict alcohol-heightened aggression in primates. | Driscoll CA et al. | β | 2017 | β |
| Preclinical voluntary drinking models for alcohol abstinence-induced affective disturbances in mice. | Holleran KM et al. | β | 2017 | β |
| Predicting early onset of intoxication versus drinking-A population-based prospective study of Norwegian adolescents. | Enstad F et al. | β | 2017 | β |
| Rat animal models for screening medications to treat alcohol use disorders. | Bell RL et al. | β | 2017 | β |
| Variable effects of chronic intermittent ethanol exposure on ethanol drinking in a genetically diverse mouse cohort. | Lopez MF et al. | β | 2017 | β |
| Addictions Neuroclinical Assessment: A Neuroscience-Based Framework for Addictive Disorders. | Kwako LE et al. | β | 2016 | β |
| A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction. | Bell RL et al. | β | 2016 | β |
| Alcohol, Substance Use and Psychosocial Competence of Adolescents in Selected Secondary Schools in Uganda: A Cross Sectional Survey. | Abbo C et al. | β | 2016 | β |
| A review of 5-HT transporter linked promoter region (5-HTTLPR) polymorphism and associations with alcohol use problems and sexual risk behaviors. | Rubens M et al. | β | 2016 | β |
| Comparison of the Temperament and Character of Patients Referred to Cosmetic Nasal Surgeon in Shiraz Hospitals, 2015. | Sharif F et al. | β | 2016 | β |
| Early-Life Adversity Interacts with FKBP5 Genotypes: Altered Working Memory and Cardiac Stress Reactivity in the Oklahoma Family Health Patterns Project. | Lovallo WR et al. | β | 2016 | β |
| Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. | Bell RL et al. | β | 2016 | β |
| Genetic overlap between impulsivity and alcohol dependence: a large-scale national twin study. | Khemiri L et al. | β | 2016 | β |
| Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures. | Kapoor M et al. | β | 2016 | β |
| Interactive Effects of Ethanol and HIV-1 Proteins on Novelty-Seeking Behaviors and Addiction-Related Gene Expression. | Wingo T et al. | β | 2016 | β |
| Linking an Anxiety-Related Personality Trait to Cardiac Autonomic Regulation in Well-Defined Healthy Adults: Harm Avoidance and Resting Heart Rate Variability. | Kao LC et al. | β | 2016 | β |
| Neurophysiological Measures and Alcohol Use Disorder (AUD): Hypothesizing Links between Clinical Severity Index and Molecular Neurobiological Patterns. | Vitali M et al. | β | 2016 | β |
| Novelty Seeking and Drug Addiction in Humans and Animals: From Behavior to Molecules. | Wingo T et al. | β | 2016 | β |
| Personality profiles in adults with attention deficit hyperactivity disorder (ADHD). | Perroud N et al. | β | 2016 | β |
| Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity. | Heinrich A et al. | β | 2016 | β |
| Prefrontal Cortical Thickness Deficit in Detoxified Alcohol-dependent Patients. | Bae S et al. | β | 2016 | β |
| Sex-specific mediation effect of the right fusiform face area volume on the association between variants in repeat length of AVPR1A RS3 and altruistic behavior in healthy adults. | Wang J et al. | β | 2016 | β |
| What the alcohol doctor ordered from the neuroscientist: Theragnostic biomarkers for personalized treatments. | Heilig M et al. | β | 2016 | β |
| Acoustic startle in alcohol-naΓ―ve male rats predicts subsequent voluntary alcohol intake and alcohol preference. | Rasmussen DD et al. | β | 2015 | β |
| Adolescent heavy drinkers' amplified brain responses to alcohol cues decrease over one month of abstinence. | Brumback T et al. | β | 2015 | β |
| Adolescent Substance Misusers with and without Delinquency: Death, Mental and Physical Disorders, and Criminal Convictions from Age 21 to 45. | Larm P et al. | β | 2015 | β |
| Co-occurrence of alcohol use disorder and behavioral addictions: relevance of impulsivity and craving. | Di Nicola M et al. | β | 2015 | β |
| Differential involvement of anxiety and novelty preference levels on oral ethanol consumption in rats. | Pelloux Y et al. | β | 2015 | β |
| Heritability of the neural response to emotional pictures: evidence from ERPs in an adult twin sample. | Weinberg A et al. | β | 2015 | β |
| Improving personality/character traits in individuals with alcohol dependence: the influence of mindfulness-oriented meditation. | Crescentini C et al. | β | 2015 | β |
| Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon. | Tikkanen R et al. | β | 2015 | β |
| Is nocturnal eating in restless legs syndrome linked to a specific psychopathological profile? A pilot study. | Marconi S et al. | β | 2015 | β |
| Lower [3H]Citalopram binding in brain areas related to social cognition in alcoholics. | KΓ€rkkΓ€inen O et al. | β | 2015 | β |
| Monoamine oxidase a promoter variable number of tandem repeats (MAOA-uVNTR) in alcoholics according to Lesch typology. | Samochowiec A et al. | β | 2015 | β |
| Multidimensional alcoholism typologies: could they guide clinical practice? Results from a 3-month prospective study. | Pombo S et al. | β | 2015 | β |
| Neuropsychological Performance in Polyconsumer Men Under Treatment. Influence of Age of Onset of Substance Use. | Capella Mdel M et al. | β | 2015 | β |
| Sex addiction and gambling disorder: similarities and differences. | FarrΓ© JM et al. | β | 2015 | β |
| Targeting glutamate uptake to treat alcohol use disorders. | Rao PS et al. | β | 2015 | β |
| Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder. | Sizoo BB et al. | β | 2015 | β |
| Temperament and character traits associated with the use of alcohol, cannabis, cocaine, benzodiazepines, and hallucinogens: evidence from a large Brazilian web survey. | Schneider R et al. | β | 2015 | β |
| The association between alcohol, marijuana use, and new and emerging tobacco products in a young adult population. | Cohn A et al. | β | 2015 | β |
| The Effects of Alcohol on Quality of Sleep. | Park SY et al. | β | 2015 | β |
| The effects of mirtazapine versus placebo on alcohol consumption in male high consumers of alcohol: a randomized, controlled trial. | de Bejczy A et al. | β | 2015 | β |
| Tracking social motivation systems deficits: the affective neuroscience view of autism. | CarrΓ© A et al. | β | 2015 | β |
| A brief history of research on the genetics of alcohol and other drug use disorders. | Schuckit MA | β | 2014 | β |
| Alcohol abuse and HIV infection: role of DRD2. | Agudelo M et al. | β | 2014 | β |
| Alcoholics have more tryptophan hydroxylase 2 mRNA and protein in the dorsal and median raphe nuclei. | Bach H et al. | β | 2014 | β |
| Alcohol use disorder in women: Risks and consequences of an adolescent onset and persistent course. | Foster KT et al. | β | 2014 | β |
| Antecedents and consequences of drug abuse in rats selectively bred for high and low response to novelty. | Flagel SB et al. | β | 2014 | β |
| Anticipatory 50 kHz ultrasonic vocalizations are associated with escalated alcohol intake in dependent rats. | Buck CL et al. | β | 2014 | β |
| Anxiety- and depressive-like traits in Warsaw alcohol high-preferring (WHP) and Warsaw alcohol low-preferring (WLP) rats. | Acewicz A et al. | β | 2014 | β |
| Applicability of Type A/B alcohol dependence in the general population. | Tam TW et al. | β | 2014 | β |
| Are there depression and anxiety genetic markers and mutations? A systematic review. | Lacerda-Pinheiro SF et al. | β | 2014 | β |
| Association of gene polymorphisms encoding dopaminergic system components and platelet MAO-B activity with alcohol dependence and alcohol dependence-related phenotypes. | Nedic Erjavec G et al. | β | 2014 | β |
| Brain structural substrates of reward dependence during behavioral performance. | Dayan E et al. | β | 2014 | β |
| Civilian stressors associated with alcohol use disorders in the National Guard. | CerdΓ‘ M et al. | β | 2014 | β |
| Clinical features of drug abuse that reflect genetic risk. | Kendler KS et al. | β | 2014 | β |
| Co-occurring psychiatric disorders and alcoholism. | Stephen Rich J et al. | β | 2014 | β |
| Differences between early-onset pathological gambling and later-onset pathological gambling: data from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). | Verdura VizcaΓno EJ et al. | β | 2014 | β |
| DRD3 gene rs6280 polymorphism may be associated with alcohol dependence overall and with Lesch type I alcohol dependence in Koreans. | Kang SG et al. | β | 2014 | β |
| Effects of histone deacetylase inhibitors on amygdaloid histone acetylation and neuropeptide Y expression: a role in anxiety-like and alcohol-drinking behaviours. | Sakharkar AJ et al. | β | 2014 | β |
| Emotional traits and affective temperaments in alcohol users, abusers and dependents in a national sample. | Leite L et al. | β | 2014 | β |
| Gender-based measurement invariance of the substance use risk profile scale. | Memetovic J et al. | β | 2014 | β |
| Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population. | Crawford A et al. | β | 2014 | β |
| Impulsive choice and anxiety-like behavior in adult rats exposed to chronic intermittent ethanol during adolescence and adulthood. | Mejia-Toiber J et al. | β | 2014 | β |
| Impulsivity and Alcohol Involvement: Multiple, Distinct Constructs and Processes. | Littlefield AK et al. | β | 2014 | β |
| Neural mechanisms of oxytocin receptor gene mediating anxiety-related temperament. | Wang J et al. | β | 2014 | β |
| Neuropsychosocial profiles of current and future adolescent alcohol misusers. | Whelan R et al. | β | 2014 | β |
| Personality disorders and the persistence of substance use disorders: A reanalysis of published NESARC findings. | VergΓ©s A et al. | β | 2014 | β |
| Prevention of alcohol-heightened aggression by CRF-R1 antagonists in mice: critical role for DRN-PFC serotonin pathway. | Quadros IM et al. | β | 2014 | β |
| Sweet-liking is associated with transformation of heavy drinking into alcohol-related problems in young adults with high novelty seeking. | Kampov-Polevoy A et al. | β | 2014 | β |
| Text messaging: are dependency and Excessive Use discretely different for Japanese university students? | Lu X et al. | β | 2014 | β |
| The adolescent origins of substance use disorders: a behavioral genetic perspective. | McGue M et al. | β | 2014 | β |
| The alcohol-preferring (P) and high-alcohol-drinking (HAD) rats--animal models of alcoholism. | McBride WJ et al. | β | 2014 | β |
| The effects of chronic alcohol self-administration on serotonin-1A receptor binding in nonhuman primates. | Hillmer AT et al. | β | 2014 | β |
| The epigenetic landscape of alcoholism. | Krishnan HR et al. | β | 2014 | β |
| The role of constraint in the development of nicotine, marijuana, and alcohol dependence in young adulthood. | Vrieze SI et al. | β | 2014 | β |
| The role of the opioid system in alcohol dependence. | Nutt DJ | β | 2014 | β |
| Translational clinical neuroscience perspectives on the cognitive and neurobiological mechanisms underlying alcohol-related aggression. | Beck A et al. | β | 2014 | β |
| Variation of types of alcoholism: review and subtypes identified in Han Chinese. | Lee SY et al. | β | 2014 | β |
| Violent behavior and driving under the influence of alcohol: prevalence and association with impulsivity among individuals in treatment for alcohol dependence in Poland. | Klimkiewicz A et al. | β | 2014 | β |
| Aberrant histone deacetylase2-mediated histone modifications and synaptic plasticity in the amygdala predisposes to anxiety and alcoholism. | Moonat S et al. | β | 2013 | β |
| Addiction and choice: theory and new data. | Heyman GM | β | 2013 | β |
| Adolescent alcohol use is predicted by childhood temperament factors before age 5, with mediation through personality and peers. | Dick DM et al. | β | 2013 | β |
| Alcohol and drug abuse among U.S. veterans: comparing associations with intimate partner substance abuse and veteran psychopathology. | Miller MW et al. | β | 2013 | β |
| Association between DRD2, 5-HTTLPR, and ALDH2 genes and specific personality traits in alcohol- and opiate-dependent patients. | Wang TY et al. | β | 2013 | β |
| A two year longitudinal outcome study of addicted health care professionals: an investigation of the role of personality variables. | Angres D et al. | β | 2013 | β |
| Centrally-mediated sensory information processing is impacted with increased alcohol consumption in college-aged individuals. | Nguyen RH et al. | β | 2013 | β |
| Comparatively preserved impulse control in late-onset opiate users. | Passetti F et al. | β | 2013 | β |
| Dare to delay? The impacts of adolescent alcohol and marijuana use onset on cognition, brain structure, and function. | Lisdahl KM et al. | β | 2013 | β |
| Decreased cardiac vagal control in drug-naive patients with panic disorder: a case-control study in Taiwan. | Chang HA et al. | β | 2013 | β |
| Decreased cardiac vagal control in drug-naΓ―ve patients with posttraumatic stress disorder. | Chang HA et al. | β | 2013 | β |
| Early life adversity contributes to impaired cognition and impulsive behavior: studies from the Oklahoma Family Health Patterns Project. | Lovallo WR et al. | β | 2013 | β |
| Genetically selected alcohol preferring rats to model human alcoholism. | Ciccocioppo R | β | 2013 | β |
| Heart rate variability in patients with fully remitted major depressive disorder. | Chang HA et al. | β | 2013 | β |
| Impact of alcohol use on thyroid function. | Balhara YP et al. | β | 2013 | β |
| Impulsivity-related personality traits and adolescent alcohol use: a meta-analytic review. | Stautz K et al. | β | 2013 | β |
| Influence of alcohol use on neural response to Go/No-Go task in college drinkers. | Ahmadi A et al. | β | 2013 | β |
| Interaction between novelty seeking and the aldehyde dehydrogenase 2 gene in heroin-dependent patients. | Lee SY et al. | β | 2013 | β |
| Interactions of a Dopamine D1 Receptor Agonist with Glutamate NMDA Receptor Antagonists on the Volitional Consumption of Ethanol by the mHEP Rat. | McMillen BA et al. | β | 2013 | β |
| Longitudinal modeling of transmissible risk in boys who subsequently develop cannabis use disorder. | Kirisci L et al. | β | 2013 | β |
| Modeling the diagnostic criteria for alcohol dependence with genetic animal models. | Crabbe JC et al. | β | 2013 | β |
| Moderate-level prenatal alcohol exposure enhances acoustic startle magnitude and disrupts prepulse inhibition in adult rhesus monkeys. | Schneider ML et al. | β | 2013 | β |
| Multi-cultural association of the serotonin transporter gene (SLC6A4) with substance use disorder. | Cao J et al. | β | 2013 | β |
| Neural sensitivity to absolute and relative anticipated reward in adolescents. | Vaidya JG et al. | β | 2013 | β |
| Novelty-seeking behaviors and the escalation of alcohol drinking after abstinence in mice are controlled by metabotropic glutamate receptor 5 on neurons expressing dopamine d1 receptors. | Parkitna JR et al. | β | 2013 | β |
| Optimizing efficiency of psychopathology assessment through quantitative modeling: development of a brief form of the Externalizing Spectrum Inventory. | Patrick CJ et al. | β | 2013 | β |
| Peter Riederer "70th birthday" neurobiological foundations of modern addiction treatment. | Jacob C | β | 2013 | β |
| Polysubstance dependent patients display a more utilitarian profile in moral decision-making than alcohol-dependent patients, depressive patients and controls. | Kornreich C et al. | β | 2013 | β |
| Prospective associations of internalizing and externalizing problems and their co-occurrence with early adolescent substance use. | Colder CR et al. | β | 2013 | β |
| Psychographic Segments of College Females and Males in Relation to Substance Use Behaviors. | Suragh TA et al. | β | 2013 | β |
| Relapse (number of detoxifications) in abstinent male alcohol-dependent patients as related to personality traits and types of tolerance to frustration. | Baars MY et al. | β | 2013 | β |
| [Relapse prevention in alcohol dependence: acamprosate and naltrexone as a combined pharmacological strategy]. | Gahr M et al. | β | 2013 | β |
| The association of DRD2 -141C and ANKK1 TaqIA polymorphisms with alcohol dependence in Korean population classified by the Lesch typology. | Lee SH et al. | β | 2013 | β |
| The burden of cyclothymia on alcohol dependence. | Pombo S et al. | β | 2013 | β |
| The dopamine system in mediating alcohol effects in humans. | Charlet K et al. | β | 2013 | β |
| The Impact of Caffeine on the Behavioral Effects of Ethanol Related to Abuse and Addiction: A Review of Animal Studies. | LΓ³pez-Cruz L et al. | β | 2013 | β |
| The Serotonin Link between Alcohol Use and Affective Disorders. | Ketcherside A et al. | β | 2013 | β |
| Using Cloninger's temperament scales to predict substance-related behaviors in adolescents: a prospective longitudinal study. | Hartman C et al. | β | 2013 | β |
| ΞΌ-Opioid receptor gene (OPRM1) polymorphism A118G: lack of association in Finnish populations with alcohol dependence or alcohol consumption. | Rouvinen-LagerstrΓΆm N et al. | β | 2013 | β |
| Acute tolerance to alcohol in at-risk binge drinkers. | Fillmore MT et al. | β | 2012 | β |
| Alcohol dependence and criminal behavior: preliminary results of an association study of environmental and genetic factors in an Italian male population. | Terranova C et al. | β | 2012 | β |
| Alcohol dependence is related to overall internalizing psychopathology load rather than to particular internalizing disorders: evidence from a national sample. | Kushner MG et al. | β | 2012 | β |
| Alexithymia in relation to parental alcoholism, everyday frontal lobe functioning and alcohol consumption in a non-clinical sample. | Lyvers M et al. | β | 2012 | β |
| A meta-analysis of temperament in axis I psychiatric disorders. | Miettunen J et al. | β | 2012 | β |
| Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity. | Bell RL et al. | β | 2012 | β |
| Association between the dopamine D2 receptor (DRD2) polymorphism and the personality traits of healthy Japanese participants. | Tsuchimine S et al. | β | 2012 | β |
| Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances. | Yang BZ et al. | β | 2012 | β |
| Bipolar disorder and alcohol use disorder: a review. | Farren CK et al. | β | 2012 | β |
| Citric acid reduces the decline in P300 amplitude induced by acute alcohol consumption in healthy adults. | Chen WX et al. | β | 2012 | β |
| Clinical indices of familial alcohol use disorder. | Kendler KS et al. | β | 2012 | β |
| Clinical phenomenology of childhood abuse-related complex PTSD in a population of female patients: patterns of personality disturbance. | Dorrepaal E et al. | β | 2012 | β |
| Commentary on comparison of alcoholism subtypes as moderators of the response to sertraline treatment. | Roache JD | β | 2012 | β |
| Comparison of alcoholism subtypes as moderators of the response to sertraline treatment. | Kranzler HR et al. | β | 2012 | β |
| Comparison of the effect of the GABAΞ receptor agonist, baclofen, and the positive allosteric modulator of the GABAB receptor, GS39783, on alcohol self-administration in 3 different lines of alcohol-preferring rats. | Maccioni P et al. | β | 2012 | β |
| Cross-sectional survey of prevalence and personality characteristics of college students with internet addiction in Wenzhou, China. | Jiang D et al. | β | 2012 | β |
| Determinants of early alcohol use in healthy adolescents: the differential contribution of neuroimaging and psychological factors. | Nees F et al. | β | 2012 | β |
| Early-onset alcohol dependence increases the acoustic startle reflex. | Schellekens AF et al. | β | 2012 | β |
| Effects of divorce on Dutch boys' and girls' externalizing behavior in Gene Γ Environment perspective: diathesis stress or differential susceptibility in the Dutch Tracking Adolescents' Individual Lives Survey study? | Nederhof E et al. | β | 2012 | β |
| Effects of the triple monoamine uptake inhibitor DOV 102,677 on alcohol-motivated responding and antidepressant activity in alcohol-preferring (P) rats. | Yang AR et al. | β | 2012 | β |
| Evidence for multiple genetic factors underlying the DSM-IV criteria for alcohol dependence. | Kendler KS et al. | β | 2012 | β |
| Genome-wide linkage scan of antisocial behavior, depression, and impulsive substance use in the UCSF family alcoholism study. | Gizer IR et al. | β | 2012 | β |
| Ina Maria Hinnenthal and Mauro Cibin on Allaman Allamani's "Failure and transformation in the relationship: between patient and therapist". | Hinnenthal IM et al. | β | 2012 | β |
| Infralimbic and dorsal raphΓ© microinjection of the 5-HT(1B) receptor agonist CP-93,129: attenuation of aggressive behavior in CFW male mice. | Faccidomo S et al. | β | 2012 | β |
| Interaction between ALDH2*1*1 and DRD2/ANKK1 TaqI A1A1 genes may be associated with antisocial personality disorder not co-morbid with alcoholism. | Lu RB et al. | β | 2012 | β |
| Interaction between serotonin transporter and serotonin receptor 1 B genes polymorphisms may be associated with antisocial alcoholism. | Wang TY et al. | β | 2012 | β |
| Introduction to the special issue "Pharmacotherapies for the treatment of alcohol abuse and dependence" and a summary of patents targeting other neurotransmitter systems. | Bell RL et al. | β | 2012 | β |
| Is the continuity of externalizing psychopathology the same in adolescents and middle-aged adults? A test of the externalizing spectrum's developmental coherence. | Vrieze SI et al. | β | 2012 | β |
| Management of alcohol abuse. | Albanese AP | β | 2012 | β |
| Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism. | Jamadar S et al. | β | 2012 | β |
| Multiple polymorphisms in genes of the adrenergic stress system confer vulnerability to alcohol abuse. | Clarke TK et al. | β | 2012 | β |
| Post-treatment outcomes in a double-blind, randomized trial of sertraline for alcohol dependence. | Kranzler HR et al. | β | 2012 | β |
| Reinforcement sensitivity theory and alcohol outcome expectancies in early adolescence. | Lopez-Vergara HI et al. | β | 2012 | β |
| Relationship between personality change and the onset and course of alcohol dependence in young adulthood. | Hicks BM et al. | β | 2012 | β |
| Sequence of alcohol involvement from early onset to young adult alcohol abuse: differential predictors and moderation by family-focused preventive intervention. | Mason WA et al. | β | 2012 | β |
| Sex hormone activity in alcohol addiction: integrating organizational and activational effects. | Lenz B et al. | β | 2012 | β |
| Stress, epigenetics, and alcoholism. | Moonat S et al. | β | 2012 | β |
| Subtypes of alcohol dependence and their effect on sexual behavior change. | Osborne V et al. | β | 2012 | β |
| Translational behaviour-genetic studies of alcohol: are we there yet? | Crabbe JC | β | 2012 | β |
| Tridimensional personalities and polymorphism of dopamine D2 receptor among heroin addicts. | Teh LK et al. | β | 2012 | β |
| ΞΊ opioid regulation of anxiety-like behavior during acute ethanol withdrawal. | Valdez GR et al. | β | 2012 | β |
| (3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu(5): Discovery of a new tool compound with activity in the OSS mouse model of addiction. | Lindsley CW et al. | β | 2011 | β |
| Alcohol research: past, present, and future. | Gunzerath L et al. | β | 2011 | β |
| Alcohol use trajectories and the ubiquitous cat's cradle: cause for concern? | Sher KJ et al. | β | 2011 | β |
| An internalizing pathway to alcohol use and disorder. | Hussong AM et al. | β | 2011 | β |
| A systemic model of doping behavior. | Johnson MB | β | 2011 | β |
| Binge Drinking: In Search of its Molecular Target via the GABA(A) Receptor. | Yang AR et al. | β | 2011 | β |
| Cognitive and neurobiological mechanisms of alcohol-related aggression. | Heinz AJ et al. | β | 2011 | β |
| Critical thoughts on current rodent models for evaluating potential treatments of alcohol addiction and withdrawal. | Ripley TL et al. | β | 2011 | β |
| Depressive and aggressive responses to frustration: development of a questionnaire and its validation in a sample of male alcoholics. | Baars MY et al. | β | 2011 | β |
| Developmental trajectories of marijuana use from adolescence to adulthood: personal predictors. | Brook JS et al. | β | 2011 | β |
| Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters. | Chen YC et al. | β | 2011 | β |
| Does variance in drinking motives explain the genetic overlap between personality and alcohol use disorder symptoms? A twin study of young women. | Littlefield AK et al. | β | 2011 | β |
| DRD2 and DRD4 in relation to regular alcohol and cannabis use among adolescents: does parenting modify the impact of genetic vulnerability? The TRAILS study. | Creemers HE et al. | β | 2011 | β |
| Friends or foes: social anxiety, peer affiliation, and drinking in middle school. | Anderson KG et al. | β | 2011 | β |
| Genetics of alcohol dependence. | Kimura M et al. | β | 2011 | β |
| Genomic analysis of individual differences in ethanol drinking: evidence for non-genetic factors in C57BL/6 mice. | Wolstenholme JT et al. | β | 2011 | β |
| Healthy subjects with a family history of alcoholism show increased stimulative subjective effects of alcohol. | SΓΆderpalm Gordh AH et al. | β | 2011 | β |
| Impulse control disorders and dopamine dysregulation in Parkinson's disease: a broader conceptual framework. | Okai D et al. | β | 2011 | β |
| Molecular targets of alcohol action: Translational research for pharmacotherapy development and screening. | Gorini G et al. | β | 2011 | β |
| Natural rewards, neuroplasticity, and non-drug addictions. | Olsen CM | β | 2011 | β |
| Personality and motivational correlates of alcohol consumption and alcohol-related problems among excessive drinking university students. | Hosier SG et al. | β | 2011 | β |
| Personality, drug preference, drug use, and drug availability. | Feldman M et al. | β | 2011 | β |
| Pharmacogenetic approaches to the treatment of alcohol addiction. | Heilig M et al. | β | 2011 | β |
| Role of the serotonergic system in alcohol dependence: from animal models to clinics. | Sari Y et al. | β | 2011 | β |
| Stress and consumption of alcohol in humans with a Type 1 family history of alcoholism in an experimental laboratory setting. | Gordh AH et al. | β | 2011 | β |
| Structural, concurrent, and predictive validity of the Substance Use Risk Profile Scale in early adolescence. | Krank M et al. | β | 2011 | β |
| The latent structure of alcohol use pathology in an epidemiological sample. | Green BA et al. | β | 2011 | β |
| The prevalence and clinical implications of self-medication among individuals with anxiety disorders. | Menary KR et al. | β | 2011 | β |
| The role of amygdaloid brain-derived neurotrophic factor, activity-regulated cytoskeleton-associated protein and dendritic spines in anxiety and alcoholism. | Moonat S et al. | β | 2011 | β |
| A cognitive model for the intergenerational transference of alcohol use behavior. | Campbell JM et al. | β | 2010 | β |
| A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function. | Tost H et al. | β | 2010 | β |
| Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? | Heilig M et al. | β | 2010 | β |
| Alcohol response and consumption in adolescent rhesus macaques: life history and genetic influences. | Schwandt ML et al. | β | 2010 | β |
| Consequences of an adolescent onset and persistent course of alcohol dependence in men: adolescent risk factors and adult outcomes. | Hicks BM et al. | β | 2010 | β |
| Course of alcohol dependence among Vietnam combat veterans and nonveteran controls. | Jacob T et al. | β | 2010 | β |
| Design, synthesis, and subtype selectivity of 3,6-disubstituted Ξ²-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse. | Yin W et al. | β | 2010 | β |
| Early onset alcohol dependence with high density of family history is not "male limited". | Magnusson A et al. | β | 2010 | β |
| Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. | Dick DM et al. | β | 2010 | β |
| Familial loading for alcoholism and offspring behavior: mediating and moderating influences. | Molina BS et al. | β | 2010 | β |
| Genetic, personality, and environmental predictors of drug use in adolescents. | Conner BT et al. | β | 2010 | β |
| Genetics of novelty seeking, amphetamine self-administration and reinstatement using inbred rats. | Meyer AC et al. | β | 2010 | β |
| Haplotypes of dopamine and serotonin transporter genes are associated with antisocial personality disorder in alcoholics. | Reese J et al. | β | 2010 | β |
| Heritability of MMPI-2 scales in the UCSF family alcoholism study. | Gizer IR et al. | β | 2010 | β |
| Human behavioral pharmacology, past, present, and future: symposium presented at the 50th annual meeting of the Behavioral Pharmacology Society. | Comer SD et al. | β | 2010 | β |
| Impact of tryptophan metabolism on the vulnerability to alcohol-related blackouts and violent impulsive behaviours. | Vignau J et al. | β | 2010 | β |
| Insight into the relationship between impulsivity and substance abuse from studies using animal models. | Winstanley CA et al. | β | 2010 | β |
| MAOA interacts with the ALDH2 gene in anxiety-depression alcohol dependence. | Lee SY et al. | β | 2010 | β |
| Medication treatment of different types of alcoholism. | Johnson BA | β | 2010 | β |
| Neural circuitry associated with risk for alcohol use disorders. | Tessner KD et al. | β | 2010 | β |
| Person-environment interaction in the prediction of alcohol abuse and alcohol dependence in adulthood. | Hill KG et al. | β | 2010 | β |
| Relapse to smoking during unaided cessation: clinical, cognitive and motivational predictors. | Powell J et al. | β | 2010 | β |
| Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes. | Stephens DN et al. | β | 2010 | β |
| Sweet liking and high novelty seeking: independent phenotypes associated with alcohol-related problems. | Lange LA et al. | β | 2010 | β |
| The 10 most important things known about addiction. | Sellman D | β | 2010 | β |
| The Multiple, Distinct Ways that Personality Contributes to Alcohol Use Disorders. | Littlefield AK et al. | β | 2010 | β |
| The role of serotonin and possible interaction of serotonin-related genes with alcohol dehydrogenase and aldehyde dehydrogenase genes in alcohol dependence-a review. | Huang CL | β | 2010 | β |
| Acute effects of alcohol on inhibitory control and information processing in high and low sensation-seekers. | Fillmore MT et al. | β | 2009 | β |
| Alcoholism: a systems approach from molecular physiology to addictive behavior. | Spanagel R | β | 2009 | β |
| Alcohol use among adolescents: a population-based study. | Strauch ES et al. | β | 2009 | β |
| An interaction between DAT1 and having an alcoholic father predicts serious alcohol problems in a sample of males. | Vaske J et al. | β | 2009 | β |
| Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. | Kimura M et al. | β | 2009 | β |
| Association between problem gambling and conduct disorder in a national survey of adolescents and young adults in the United States. | Welte JW et al. | β | 2009 | β |
| Association of the dopamine D2 receptor gene with alcohol dependence: haplotypes and subgroups of alcoholics as key factors for understanding receptor function. | Kraschewski A et al. | β | 2009 | β |
| Behavioral inhibition and activation systems: differences in substance use expectancy organization and activation in memory. | Simons JS et al. | β | 2009 | β |
| Comparison of temperament and character between early- and late-onset Korean male pathological gamblers. | Shin YC et al. | β | 2009 | β |
| Constitutional mechanisms of vulnerability and resilience to nicotine dependence. | Hiroi N et al. | β | 2009 | β |
| D2 dopamine receptor (DRD2) gene, P300, and personality in children of alcoholics. | Antolin T et al. | β | 2009 | β |
| Differential effects of 5-HTTLPR and DRD2/ANKK1 polymorphisms on electrocortical measures of error and feedback processing in children. | Althaus M et al. | β | 2009 | β |
| Do genetic and individual risk factors moderate the efficacy of motivational enhancement therapy? Drinking outcomes with an emerging adult sample. | Feldstein Ewing SW et al. | β | 2009 | β |
| Dopamine D4 receptor gene exon III polymorphism associated with binge drinking attitudinal phenotype. | Vaughn MG et al. | β | 2009 | β |
| Drinking histories in alcohol-use-disordered youth: preliminary findings on relationships to platelet serotonin transporter expression with genotypes of the serotonin transporter. | Dawes MA et al. | β | 2009 | β |
| Enhanced 5-HT(2A) receptors in brain stem and ALDH activity in brain stem and liver: 5-HT(2A) regulation on ALDH in primary hepatocytes cultures in vitro. | George AK et al. | β | 2009 | β |
| Examining factors in the Research Institute on Addictions Self-Inventory (RIASI): Associations with alcohol use and problems at assessment and follow-up. | Mann RE et al. | β | 2009 | β |
| From the brain to bad behaviour and back again: neurocognitive and psychobiological mechanisms of driving while impaired by alcohol. | Brown TG et al. | β | 2009 | β |
| Frontal brain dysfunction in alcoholism with and without antisocial personality disorder. | Oscar-Berman M et al. | β | 2009 | β |
| Gender differences in factors influencing alcohol use and drinking progression among adolescents. | Schulte MT et al. | β | 2009 | β |
| Genetic and environmental influences on externalizing behavior and alcohol problems in adolescence: a female twin study. | Knopik VS et al. | β | 2009 | β |
| Genetic and non-genetic influences on the development of co-occurring alcohol problem use and internalizing symptomatology in adolescence: a review. | Saraceno L et al. | β | 2009 | β |
| [Genetic factors of alcohol-dependence]. | Pinto E et al. | β | 2009 | β |
| Genome-wide association study of alcohol dependence. | Treutlein J et al. | β | 2009 | β |
| Influence of antisocial and psychopathic traits on decision-making biases in alcoholics. | Miranda R et al. | β | 2009 | β |
| Long-term behavioral changes in response to early developmental exposure to ethanol in zebrafish. | Fernandes Y et al. | β | 2009 | β |
| MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder. | Lee SY et al. | β | 2009 | β |
| Negative affectivity, effortful control, and attention to threat-relevant stimuli. | Lonigan CJ et al. | β | 2009 | β |
| Operant sensation seeking engages similar neural substrates to operant drug seeking in C57 mice. | Olsen CM et al. | β | 2009 | β |
| Personality traits among ADHD adults: implications of late-onset and subthreshold diagnoses. | Faraone SV et al. | β | 2009 | β |
| Positron emission tomography imaging of the serotonin transporter and 5-HT(1A) receptor in alcohol dependence. | Martinez D et al. | β | 2009 | β |
| Prospective relations between growth in drinking and familial stressors across adolescence. | King KM et al. | β | 2009 | β |
| Subtypes of clients with serious mental illness and co-occurring disorders: latent-class trajectory analysis. | Xie H et al. | β | 2009 | β |
| Sweet liking phenotype, alcohol craving and response to naltrexone treatment in alcohol dependence. | Garbutt JC et al. | β | 2009 | β |
| Temperamental risk factors for adolescent cannabis use: a systematic review of prospective general population studies. | Creemers HE et al. | β | 2009 | β |
| The P300 event-related potential and its possible role as an endophenotype for studying substance use disorders: a review. | Singh SM et al. | β | 2009 | β |
| The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence. | Lee SY et al. | β | 2009 | β |
| The Substance Use Risk Profile Scale: a scale measuring traits linked to reinforcement-specific substance use profiles. | Woicik PA et al. | β | 2009 | β |
| The TaqI A DRD2 polymorphism in type II alcohol dependence: a marker of age at onset or of a familial disease? | Pinto E et al. | β | 2009 | β |
| Two types of classification in female alcoholism. | Traber R et al. | β | 2009 | β |
| Typologies of alcohol dependence. From Jellinek to genetics and beyond. | Leggio L et al. | β | 2009 | β |
| Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics. | Beck A et al. | β | 2009 | β |
| Adolescent stressors, psychopathology, and young adult substance dependence: a prospective study. | King KM et al. | β | 2008 | β |
| [Alcohol dependence: diagnosis and treatment]. | Perney P et al. | β | 2008 | β |
| Alcohol, psychological dysregulation, and adolescent brain development. | Clark DB et al. | β | 2008 | β |
| Analysis of single nucleotide polymorphisms and haplotypes in the neuropeptide Y gene: no evidence for association with alcoholism in a German population sample. | Zill P et al. | β | 2008 | β |
| Approach to the genetics of alcoholism: a review based on pathophysiology. | KΓΆhnke MD | β | 2008 | β |
| A psychometric evaluation of the revised Temperament and Character Inventory (TCI-R) and the TCI-140. | Farmer RF et al. | β | 2008 | β |
| Association between the alpha-2C-adrenergic receptor gene and attention deficit hyperactivity disorder in a Korean sample. | Cho SC et al. | β | 2008 | β |
| Autonomic activation associated with ethanol self-administration in adult female P rats. | Bell RL et al. | β | 2008 | β |
| Baclofen reduces ethanol intake in high-alcohol-drinking University of Chile bibulous rats. | Quintanilla ME et al. | β | 2008 | β |
| Children of alcoholics in Spain: from risk to pathology. Results from the ALFIL program. | DΓaz R et al. | β | 2008 | β |
| Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice. | KelaΓ― S et al. | β | 2008 | β |
| Clinical and temperamental differences between early- and late-onset alcoholism in Korean men. | Lim SW et al. | β | 2008 | β |
| Clusters of alcohol use disorders diagnostic criteria and predictors of alcohol use after liver transplantation for alcoholic liver disease. | DiMartini A et al. | β | 2008 | β |
| Cocaine withdrawal symptoms identify "Type B" cocaine-dependent patients. | Ahmadi J et al. | β | 2008 | β |
| Comparison of longitudinal phenotypes based on alternate heavy drinking cut scores: a systematic comparison of trajectory approaches III. | Jackson KM et al. | β | 2008 | β |
| Density of familial alcoholism and its effects on alcohol use and problems in college students. | Capone C et al. | β | 2008 | β |
| Differences in acute alcohol-induced behavioral responses among zebrafish populations. | Gerlai R et al. | β | 2008 | β |
| Ethanol induces stronger dopamine release in nucleus accumbens (shell) of alcohol-preferring (bibulous) than in alcohol-avoiding (abstainer) rats. | Bustamante D et al. | β | 2008 | β |
| Familial transmission of derived phenotypes for molecular genetic studies of substance use disorders. | Faraone SV et al. | β | 2008 | β |
| Hypothalamic-pituitary-adrenal axis response to stress in male DUI recidivists. | Couture S et al. | β | 2008 | β |
| Impulsive errors on a Go-NoGo reaction time task: disinhibitory traits in relation to a family history of alcoholism. | Saunders B et al. | β | 2008 | β |
| Innate differences in the expression of brain-derived neurotrophic factor in the regions within the extended amygdala between alcohol preferring and nonpreferring rats. | Prakash A et al. | β | 2008 | β |
| Long-term citalopram maintenance in mice: selective reduction of alcohol-heightened aggression. | Caldwell EE et al. | β | 2008 | β |
| Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations. | Luo X et al. | β | 2008 | β |
| Neuropharmacology of alcohol addiction. | Vengeliene V et al. | β | 2008 | β |
| Ordered subsets linkage analysis of antisocial behavior in substance use disorder among participants in the Collaborative Study on the Genetics of Alcoholism. | Jacobson KC et al. | β | 2008 | β |
| Prediction of serotonergic treatment efficacy using age of onset and Type A/B typologies of alcoholism. | Roache JD et al. | β | 2008 | β |
| Proton magnetic resonance spectroscopy in alcohol use disorders: a potential new endophenotype? | Meyerhoff DJ et al. | β | 2008 | β |
| Psychopathy Subtypes among African American County Jail Inmates. | Swogger MT et al. | β | 2008 | β |
| Review. Genetics of addictions: strategies for addressing heterogeneity and polygenicity of substance use disorders. | Wong CC et al. | β | 2008 | β |
| Role of Serotonin and Dopamine System Interactions in the Neurobiology of Impulsive Aggression and its Comorbidity with other Clinical Disorders. | Seo D et al. | β | 2008 | β |
| Social rank and social separation as determinants of alcohol drinking in squirrel monkeys. | McKenzie-Quirk SD et al. | β | 2008 | β |
| Temperament, character, and dissociation among detoxified male inpatients with alcohol dependency. | Evren C et al. | β | 2008 | β |
| Temperament, substance use and psychopathology in a prisoner population: implications for treatment. | Allnutt S et al. | β | 2008 | β |
| The A1 allele of the D2 dopamine receptor gene region, alcohol expectancies and drinking refusal self-efficacy are associated with alcohol dependence severity. | Connor JP et al. | β | 2008 | β |
| The association between DRD2/ANKK1, 5-HTTLPR gene, and specific personality trait on antisocial alcoholism among Han Chinese in Taiwan. | Wu CY et al. | β | 2008 | β |
| The MAO-A gene, platelet MAO-B activity and psychosocial environment in adolescent female alcohol-related problem behaviour. | Nilsson KW et al. | β | 2008 | β |
| The role of 5-HT3 receptors in drug abuse and as a target for pharmacotherapy. | Engleman EA et al. | β | 2008 | β |
| Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings. | Johnson BA | β | 2008 | β |
| Anger, depression and personality dimensions in patients with migraine without aura. | Abbate-Daga G et al. | β | 2007 | β |
| Anxiety disorders: treatable regardless of the severity of comorbid alcohol dependence. | SchadΓ© A et al. | β | 2007 | β |
| Association of THR105Ile, a functional polymorphism of histamine N-methyltransferase (HNMT), with alcoholism in German Caucasians. | Reuter M et al. | β | 2007 | β |
| Attention-deficit hyperactivity disorder moderates the life stress pathway to alcohol problems in children of alcoholics. | Marshal MP et al. | β | 2007 | β |
| Decreased dopamine D(2) receptor function in cerebral cortex and brain stem: their role in hepatic ALDH regulation in ethanol treated rats. | George AK et al. | β | 2007 | β |
| Deriving phenotypes for molecular genetic studies of substance use disorders: a family study approach. | Faraone SV et al. | β | 2007 | β |
| Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol. | Quintanilla ME et al. | β | 2007 | β |
| Effect of DOV 102,677 on the volitional consumption of ethanol by Myers' high ethanol-preferring rat. | McMillen BA et al. | β | 2007 | β |
| Energy substrate metabolism among habitually violent alcoholic offenders having antisocial personality disorder. | Virkkunen M et al. | β | 2007 | β |
| Ethanol alters the effect of kappa receptor ligands on dopamine release in the nucleus accumbens. | Lindholm S et al. | β | 2007 | β |
| Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference. | Hansson AC et al. | β | 2007 | β |
| Ideal self-image congruency as a motivator for smoking: the moderating effects of personality traits. | Chang C | β | 2007 | β |
| Identifying subtypes of criminal psychopaths: A replication and extension. | Swogger MT et al. | β | 2007 | β |
| [Impact of personality on the alcohol withdrawal syndrome intensity: a preliminary study with the Cloninger's model]. | Coton X et al. | β | 2007 | β |
| Impulsivity and negative emotionality associated with substance use problems and Cluster B personality in college students. | James LM et al. | β | 2007 | β |
| Impulsivity, neural deficits, and the addictions: the "oops" factor in relapse. | Adinoff B et al. | β | 2007 | β |
| Intact preference conditioning in acute intoxication despite deficient declarative knowledge and working memory. | Balodis IM et al. | β | 2007 | β |
| Internalizing and externalizing subtypes in female sexual assault survivors: implications for the understanding of complex PTSD. | Miller MW et al. | β | 2007 | β |
| Linking antisocial behavior, substance use, and personality: an integrative quantitative model of the adult externalizing spectrum. | Krueger RF et al. | β | 2007 | β |
| Migrating identities: the relational constitution of drug use and addiction. | Hughes K | β | 2007 | β |
| Monoamine oxidase-A polymorphisms might modify the association between the dopamine D2 receptor gene and alcohol dependence. | Huang SY et al. | β | 2007 | β |
| Nucleotide sequence variation within the human tyrosine kinase B neurotrophin receptor gene: association with antisocial alcohol dependence. | Xu K et al. | β | 2007 | β |
| Origin of the comorbidity of anxiety disorders and alcohol dependence: findings of a general population study. | Marquenie LA et al. | β | 2007 | β |
| Personality traits of agreeableness and extraversion are associated with ADH4 variation. | Luo X et al. | β | 2007 | β |
| Polymorphisms in the mu-opioid receptor gene (OPRM1) and the implications for alcohol dependence in humans. | van der Zwaluw CS et al. | β | 2007 | β |
| Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan. | Wang TJ et al. | β | 2007 | β |
| Preclinical and clinical pharmacology of alcohol dependence. | Tambour S et al. | β | 2007 | β |
| Prevalence and correlates of binge eating disorder in a community sample. | Grucza RA et al. | β | 2007 | β |
| Psychoactive substances and the provision of specialized care: the case of Espirito Santo. | Siqueira MM et al. | β | 2007 | β |
| Rates of ethanol metabolism decrease in sons of alcoholics following a priming dose of ethanol. | Bradford BU et al. | β | 2007 | β |
| Responding for brain stimulation reward in the bed nucleus of the stria terminalis in alcohol-preferring rats following alcohol and amphetamine pretreatments. | Eiler WJ et al. | β | 2007 | β |
| Specific personality traits and dopamine, serotonin genes in anxiety-depressive alcoholism among Han Chinese in Taiwan. | Lin SC et al. | β | 2007 | β |
| Substance use disorder among adoptees: a clinical comparative study. | Westermeyer J et al. | β | 2007 | β |
| Temperament and character in patients with borderline personality disorder taking gender and comorbidity into account. | Barnow S et al. | β | 2007 | β |
| Temperament and character model of personality profile of alcohol- and drug-dependent inpatients. | Evren C et al. | β | 2007 | β |
| The functional impact of SLC6 transporter genetic variation. | Hahn MK et al. | β | 2007 | β |
| The relationship between PROP and ethanol preferences: an evaluation of 4 inbred mouse strains. | White TL et al. | β | 2007 | β |
| Activation of adenosine A1 receptors reduces anxiety-like behavior during acute ethanol withdrawal (hangover) in mice. | Prediger RD et al. | β | 2006 | β |
| Alcohol, drugs, and attention-deficit/ hyperactivity disorder: a model for the study of addictions in youth. | Wilens TE et al. | β | 2006 | β |
| Approach and avoidance motivation in the social domain. | Elliot AJ et al. | β | 2006 | β |
| Assessment of the aversive and rewarding effects of alcohol in Fischer and Lewis rats. | Roma PG et al. | β | 2006 | β |
| Blunted hypothalamic-pituitary-adrenocortical axis responsivity to stress in persons with a family history of alcoholism. | Sorocco KH et al. | β | 2006 | β |
| Characterizing alcohol dependence: transitions during young and middle adulthood. | Jackson KM et al. | β | 2006 | β |
| Chronic daily ethanol and withdrawal: 6. Effects on rat sympathoadrenal activity during "abstinence". | Rasmussen DD et al. | β | 2006 | β |
| Clinical and genetic characteristics of Korean male alcoholics with and without attention deficit hyperactivity disorder. | Kim JW et al. | β | 2006 | β |
| Comorbidity of substance use with depression and other mental disorders: from Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) to DSM-V. | Nunes EV et al. | β | 2006 | β |
| Comparison of liver hemodynamics according to doppler ultrasonography in alcoholic patients subtyped by Cloninger classification and non-alcoholic healthy subjects. | Sumru Cosar Z et al. | β | 2006 | β |
| Comparison of VTA dopamine neuron activity in lines of rats selectively bred to prefer or avoid alcohol. | Morzorati SL et al. | β | 2006 | β |
| Concurrent validity of the Alcohol Use Disorders Identification Test (AUDIT) and AUDIT zones in defining levels of severity among out-patients with alcohol dependence in the COMBINE study. | Donovan DM et al. | β | 2006 | β |
| Conduct disorder and antisocial personality disorder in persons with severe psychiatric and substance use disorders. | Mueser KT et al. | β | 2006 | β |
| Coping styles of type I and type II alcohol-dependent men undergoing treatment. | Moussas G et al. | β | 2006 | β |
| Cortisol secretion patterns in addiction and addiction risk. | Lovallo WR | β | 2006 | β |
| Daily patterns of ethanol drinking in peri-adolescent and adult alcohol-preferring (P) rats. | Bell RL et al. | β | 2006 | β |
| DBH*444G/A polymorphism of the dopamine-beta-hydroxylase gene is associated with alcoholism but not with severe alcohol withdrawal symptoms. | KΓΆhnke MD et al. | β | 2006 | β |
| Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms. | Rothenfluh A et al. | β | 2006 | β |
| Does pervasive developmental disorder protect children and adolescents against drug and alcohol use? | Santosh PJ et al. | β | 2006 | β |
| Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. | Dick DM et al. | β | 2006 | β |
| Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats. | Vendruscolo LF et al. | β | 2006 | β |
| Family based association analysis of statistically derived quantitative traits for drug use in ADHD and the dopamine transporter gene. | Lasky-Su J et al. | β | 2006 | β |
| Glutamic acid in withdrawal and weaning in patients classified according to Cloninger's and Lesch's typologies. | Walter H et al. | β | 2006 | β |
| Individual differences in drug abuse vulnerability: d-amphetamine and sensation-seeking status. | Kelly TH et al. | β | 2006 | β |
| Longitudinal brain magnetic resonance imaging study of the alcohol-preferring rat. Part II: effects of voluntary chronic alcohol consumption. | Pfefferbaum A et al. | β | 2006 | β |
| Negative Mood Regulation (NMR) expectancies, mood, and affect intensity among clients in substance disorder treatment facilities. | Thorberg FA et al. | β | 2006 | β |
| New findings on the genetic influences on alcohol use and dependence. | Higuchi S et al. | β | 2006 | β |
| Non-human primate models of inheritance vulnerability to alcohol use disorders. | Barr CS et al. | β | 2006 | β |
| Phenotypic characterization of genetically selected Sardinian alcohol-preferring (sP) and -non-preferring (sNP) rats. | Colombo G et al. | β | 2006 | β |
| Possible role of nerve growth factor in the pathogenesis of alcohol dependence. | Yoon SJ et al. | β | 2006 | β |
| Protein expression changes in the nucleus accumbens and amygdala of inbred alcohol-preferring rats given either continuous or scheduled access to ethanol. | Bell RL et al. | β | 2006 | β |
| Psychologic considerations in the management of oral surgical patients. | Bodner S | β | 2006 | β |
| PTSD and substance-related problems: the mediating roles of disconstraint and negative emotionality. | Miller MW et al. | β | 2006 | β |
| Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients. | Patkar AA et al. | β | 2006 | β |
| Substance use disorder trajectory classes: diachronic integration of onset age, severity, and course. | Clark DB et al. | β | 2006 | β |
| Subtypes of illicit drug users: a latent class analysis of data from an Australian twin sample. | Lynskey MT et al. | β | 2006 | β |
| Temperament characteristics, as assessed by the tridimensional personality questionnaire, moderate the response to sertraline in depressed opiate-dependent methadone patients. | Raby WN et al. | β | 2006 | β |
| The alcohol-preferring P rat and animal models of excessive alcohol drinking. | Bell RL et al. | β | 2006 | β |
| The association between alcohol misuse and suicidal behaviour. | Brady J | β | 2006 | β |
| The Australian Twin ADHD Project: current status and future directions. | Bennett KS et al. | β | 2006 | β |
| The next challenge for psychiatric genetics: characterizing the risk associated with identified genes. | Dick DM et al. | β | 2006 | β |
| The Tridimensional Personality Questionnaire: changes during psychological treatment of social phobia. | Hofmann SG et al. | β | 2006 | β |
| The Type A-Type B classification in a community sample of problem drinkers: structural and predictive validity. | Carpenter KM et al. | β | 2006 | β |
| Understanding differences in marijuana use among urban Black and suburban White high school students from two U.S. community samples. | Chen KW et al. | β | 2006 | β |
| Working memory and decision-making biases in young adults with a family history of alcoholism: studies from the Oklahoma family health patterns project. | Lovallo WR et al. | β | 2006 | β |
| Adolescent alcohol drinking and its long-range consequences. Studies with animal models. | McBride WJ et al. | β | 2005 | β |
| Adversity among drug users: relationship to impulsivity. | Hayaki J et al. | β | 2005 | β |
| Alcohol and aldehyde dehydrogenase polymorphisms in men with type I and Type II alcoholism. | Chai YG et al. | β | 2005 | β |
| Alcohol dependence and gene x environment interaction in emotion regulation: Is serotonin the link? | Lesch KP | β | 2005 | β |
| A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence. | Mottagui-Tabar S et al. | β | 2005 | β |
| Anxiety and risk for substance dependence among late adolescents/young adults. | Lopez B et al. | β | 2005 | β |
| Applications of morphometric and diffusion tensor magnetic resonance imaging to the study of brain abnormalities in the alcoholism spectrum. | Daurignac E et al. | β | 2005 | β |
| Association between the serotonin transporter gene and alcohol consumption in social drinkers. | MunafΓ² MR et al. | β | 2005 | β |
| Association of the -141C Del variant of the dopamine D2 receptor (DRD2) with positive family history and suicidality in German alcoholics. | Johann M et al. | β | 2005 | β |
| Association of the serotonin transporter gene polymorphism with Korean male alcoholics. | Kweon YS et al. | β | 2005 | β |
| Association study of catechol-O-methyltransferase gene polymorphism in Korean male alcoholics. | Kweon YS et al. | β | 2005 | β |
| A three-axes approach of subtyping the alcohol dependence syndrome. | Wiesbeck GA et al. | β | 2005 | β |
| Conceptual framework for the etiology of alcoholism: a "kindling"/stress hypothesis. | Breese GR et al. | β | 2005 | β |
| CREB gene transcription factors: role in molecular mechanisms of alcohol and drug addiction. | Pandey SC et al. | β | 2005 | β |
| Deep serotonergic and dopaminergic structures in fetal alcoholic syndrome: a study with nor-beta-CIT-single-photon emission computed tomography and magnetic resonance imaging volumetry. | Riikonen RS et al. | β | 2005 | β |
| Deficits in amygdaloid cAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism. | Pandey SC et al. | β | 2005 | β |
| Differences in impulsivity and risk-taking propensity between primary users of crack cocaine and primary users of heroin in a residential substance-use program. | Bornovalova MA et al. | β | 2005 | β |
| DRD2 genotypes and substance use in adolescent children of alcoholics. | Conner BT et al. | β | 2005 | β |
| EEG spectral changes in treatment-naive, actively drinking alcoholics. | Fein G et al. | β | 2005 | β |
| Effects of ethanol on locomotor and anxiety-like behaviors and the acquisition of ethanol intake in Lewis and spontaneously hypertensive rats. | Da Silva GE et al. | β | 2005 | β |
| Efficacy of antidepressants in substance use disorders with and without comorbid depression. A systematic review and meta-analysis. | Torrens M et al. | β | 2005 | β |
| Ethanol withdrawal and proclivity are inversely related in rats selectively bred for differential saccharin intake. | Dess NK et al. | β | 2005 | β |
| Factors influencing susceptibility to compulsive dopaminergic drug use in Parkinson disease. | Evans AH et al. | β | 2005 | β |
| Genetic influences in emotional dysfunction and alcoholism-related brain damage. | Oscar-Berman M et al. | β | 2005 | β |
| Genetic susceptibility to substance dependence. | Hiroi N et al. | β | 2005 | β |
| Heritability of substance dependence in a native American population. | Wilhelmsen KC et al. | β | 2005 | β |
| Lipid peroxidation and antioxidant enzyme activities in erythrocytes of type I and II alcoholics. | UΓ§ar G et al. | β | 2005 | β |
| Meta-analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence. | Feinn R et al. | β | 2005 | β |
| No alcoholism-protection effects of ADH1B*2 allele in antisocial alcoholics among Han Chinese in Taiwan. | Lu RB et al. | β | 2005 | β |
| Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene. | Pogorelov VM et al. | β | 2005 | β |
| Predictors of acamprosate efficacy: results from a pooled analysis of seven European trials including 1485 alcohol-dependent patients. | Verheul R et al. | β | 2005 | β |
| [Prevalence and comorbidity of psychiatric disorders in the French general population]. | LΓ©pine JP et al. | β | 2005 | β |
| Risk-taking on tests sensitive to ventromedial prefrontal cortex dysfunction predicts early relapse in alcohol dependency: a pilot study. | Bowden-Jones H et al. | β | 2005 | β |
| Role of the serotonin transporter gene and family function in adolescent alcohol consumption. | Nilsson KW et al. | β | 2005 | β |
| Similarities and differences of longitudinal phenotypes across alternate indices of alcohol involvement: a methodologic comparison of trajectory approaches. | Jackson KM et al. | β | 2005 | β |
| Stage model of recovery for chemically dependent adolescents: part 2--Model evaluation and treatment implications. | Blumberg D | β | 2005 | β |
| Stress enhancement of craving during sobriety: a risk for relapse. | Breese GR et al. | β | 2005 | β |
| The utility of neurophysiological markers in the study of alcoholism. | Porjesz B et al. | β | 2005 | β |
| Thr105Ile, a functional polymorphism of histamine N-methyltransferase, is associated with alcoholism in two independent populations. | Oroszi G et al. | β | 2005 | β |
| Two types of classification for male opioid dependence: identification of an opioid addict with depressive features. | Modestin J et al. | β | 2005 | β |
| Voluntary alcohol intake in two rat lines selectively bred for learned helpless and non-helpless behavior. | Vengeliene V et al. | β | 2005 | β |
| ADH1B*1, ADH1C*2, DRD2 (-141C Ins), and 5-HTTLPR are associated with alcoholism in Mexican American men living in Los Angeles. | Konishi T et al. | β | 2004 | β |
| Alcohol expectancy mediation of biopsychosocial risk: complex patterns of mediation. | Darkes J et al. | β | 2004 | β |
| Alcoholic subtypes: are two sufficient? | Windle M et al. | β | 2004 | β |
| An overview of the development of medications including novel anticonvulsants for the treatment of alcohol dependence. | Johnson BA | β | 2004 | β |
| Antidepressant treatment of co-occurring depression and alcohol dependence. | Pettinati HM | β | 2004 | β |
| Anxiety as a predictor of alcohol preference in rats? | Langen B et al. | β | 2004 | β |
| A prospective study of intraindividual and peer influences on adolescents' heterosexual romantic and sexual behavior. | Zimmer-Gembeck MJ et al. | β | 2004 | β |
| Arginine vasopressin and adrenocorticotropin secretion in response to psychosocial stress is attenuated by ethanol in sons of alcohol-dependent fathers. | Zimmermann U et al. | β | 2004 | β |
| Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. | Verdejo-GarcΓa A et al. | β | 2004 | β |
| Differences in peripheral noradrenergic function among actively drinking and abstinent alcohol-dependent individuals. | Patkar AA et al. | β | 2004 | β |
| Early adolescent through young adult alcohol and marijuana use trajectories: early predictors, young adult outcomes, and predictive utility. | Flory K et al. | β | 2004 | β |
| Effect of ethanol on hypothalamic-pituitary-adrenal system response to psychosocial stress in sons of alcohol-dependent fathers. | Zimmermann U et al. | β | 2004 | β |
| Effects of heavy drinking, binge drinking, and family history of alcoholism on regional brain metabolites. | Meyerhoff DJ et al. | β | 2004 | β |
| Efficacy of fluvoxamine in preventing relapse in alcohol dependence: a one-year, double-blind, placebo-controlled multicentre study with analysis by typology. | Chick J et al. | β | 2004 | β |
| [Explanatory models for alcohol and drugs use and the nursing practice]. | Pillon SC et al. | β | 2004 | β |
| GABA(A) and opioid receptors of the central nucleus of the amygdala selectively regulate ethanol-maintained behaviors. | Foster KL et al. | β | 2004 | β |
| Genetics, pharmacokinetics, and neurobiology of adolescent alcohol use. | β | β | 2004 | β |
| Have Halpern et al. (2004) detected 'residual neuropsychological effects' of MDMA? Not likely. | Lyvers M et al. | β | 2004 | β |
| Immunocytochemical study of the forebrain serotonergic innervation in Sardinian alcohol-preferring rats. | Casu MA et al. | β | 2004 | β |
| Impulsivity in abstinent alcohol-dependent patients: relation to control subjects and type 1-/type 2-like traits. | Bjork JM et al. | β | 2004 | β |
| Increased anxiety-like behavior and ethanol self-administration in dependent rats: reversal via corticotropin-releasing factor-2 receptor activation. | Valdez GR et al. | β | 2004 | β |
| Mismatch negativity: no difference between treatment-naive alcoholics and controls. | Fein G et al. | β | 2004 | β |
| Partial deletion of the cAMP response element-binding protein gene promotes alcohol-drinking behaviors. | Pandey SC et al. | β | 2004 | β |
| Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. | Huang SY et al. | β | 2004 | β |
| Pretransplant psychiatric and medical comorbidity of alcoholic liver disease patients who received liver transplant. | DiMartini A et al. | β | 2004 | β |
| Prevalence and correlates of past-year substance use, abuse, and dependence in a suburban community sample of high-school students. | Chen K et al. | β | 2004 | β |
| Psychopathology and treatment outcome of drug dependent women in a perinatal program. | Ingersoll KS et al. | β | 2004 | β |
| Sensitivity to reward: implications for overeating and overweight. | Davis C et al. | β | 2004 | β |
| Serotonin-3 receptors in the actions of alcohol, alcohol reinforcement, and alcoholism. | McBride WJ et al. | β | 2004 | β |
| Sweet liking, novelty seeking, and gender predict alcoholic status. | Kampov-Polevoy AB et al. | β | 2004 | β |
| Temperament and adolescent substance use: a transactional analysis of emerging self-control. | Wills TA et al. | β | 2004 | β |
| The gene transcription factor cyclic AMP-responsive element binding protein: role in positive and negative affective states of alcohol addiction. | Pandey SC | β | 2004 | β |
| The High-Ethanol Preferring rat as a model to study the shift between alcohol abuse and dependence. | Terenina-Rigaldie E et al. | β | 2004 | β |
| The Italian version of the Obsessive-Compulsive Drinking Scale: validation, comparison with the other versions, and difference between type 1- and type 2-like alcoholics. | Janiri L et al. | β | 2004 | β |
| The natural history of adolescent alcohol use disorders. | Clark DB | β | 2004 | β |
| The role of brain oscillations as functional correlates of cognitive systems: a study of frontal inhibitory control in alcoholism. | Kamarajan C et al. | β | 2004 | β |
| The use of adolescent nonhuman primates to model human alcohol intake: neurobiological, genetic, and psychological variables. | Barr CS et al. | β | 2004 | β |
| Trajectories of alcohol and drug use and dependence from adolescence to adulthood: the effects of familial alcoholism and personality. | Chassin L et al. | β | 2004 | β |
| Using latent trait modeling to conceptualize an alcohol problems continuum. | Krueger RF et al. | β | 2004 | β |
| A classification of substance-dependent men on temperament and severity variables. | Henderson MJ et al. | β | 2003 | β |
| A comparative study on alcohol-preferring rat lines: effects of deprivation and stress phases on voluntary alcohol intake. | Vengeliene V et al. | β | 2003 | β |
| Advances in nonhuman primate alcohol abuse and alcoholism research. | Grant KA et al. | β | 2003 | β |
| Age at onset typology in opioid-dependent men: an exploratory study from India. | De B et al. | β | 2003 | β |
| A genome-wide search for quantitative trait loci influencing substance dependence vulnerability in adolescence. | Stallings MC et al. | β | 2003 | β |
| Aggressiveness, family history of alcoholism, and the heart rate response to alcohol intoxication. | Assaad JM et al. | β | 2003 | β |
| Alcohol and withdrawal: from animal research to clinical issues. | De Witte P et al. | β | 2003 | β |
| Alcohol intake in social housing and in isolation before puberty and its effects on voluntary alcohol consumption in adulthood. | JuΓ‘rez J et al. | β | 2003 | β |
| Alcoholism risk and the P300 event-related brain potential: modality, task, and gender effects. | Reese C et al. | β | 2003 | β |
| Alcohol use and other psychiatric disorders in the formerly homeless and never homeless: prevalence, age of onset, comorbidity, temporal sequencing, and service utilization. | Reardon ML et al. | β | 2003 | β |
| Alcohol use disorders and psychological distress: a prospective state-trait analysis. | Jackson KM et al. | β | 2003 | β |
| Altered affective modulation of the startle reflex in alcoholics with antisocial personality disorder. | Miranda R et al. | β | 2003 | β |
| Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence. | Valdez GR et al. | β | 2003 | β |
| Association between sweet preference and paternal history of alcoholism in psychiatric and substance abuse patients. | Kampov-Polevoy AB et al. | β | 2003 | β |
| A study of psychiatric comorbidity in alcohol dependence. | Vohra AK et al. | β | 2003 | β |
| Boredom and psychotic disorders: cognitive and motivational issues. | Todman M | β | 2003 | β |
| Candidate genes for alcohol dependence: a review of genetic evidence from human studies. | Dick DM et al. | β | 2003 | β |
| Cognitive-behavioral profiles of college risk-takers with Type II and psychopathic personality traits. | Hartzler B et al. | β | 2003 | β |
| College students and problematic drinking: a review of the literature. | Ham LS et al. | β | 2003 | β |
| D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes. | Noble EP | β | 2003 | β |
| Differential associations of sex and D2 dopamine receptor (DRD2) genotype with negative affect and other substance abuse risk markers in children of alcoholics. | Berman SM et al. | β | 2003 | β |
| Effects of alcohol on cardiovascular reactivity and the mediation of aggressive behaviour in adult men and women. | Hoaken PN et al. | β | 2003 | β |
| Effects of ondansetron in early- versus late-onset alcoholics: a prospective, open-label study. | Kranzler HR et al. | β | 2003 | β |
| [ERPs (N200, P300 and CNV) in alcoholics: relapse risk assessment]. | Cristini P et al. | β | 2003 | β |
| Ethanol consumption and DRD2 gene TaqI a polymorphism among socially drinking males. | Hallikainen T et al. | β | 2003 | β |
| Functional variation in promoter region of monoamine oxidase A and subtypes of alcoholism: haplotype analysis. | Parsian A et al. | β | 2003 | β |
| Genetic analysis of the psychomotor stimulant effect of ethanol. | Downing C et al. | β | 2003 | β |
| Genetic influences on the association between personality risk factors and alcohol use and abuse. | Mustanski BS et al. | β | 2003 | β |
| Genetics of behaviour: phenotypic and molecular study of rats derived from high- and low-alcohol consuming lines. | Terenina-Rigaldie E et al. | β | 2003 | β |
| G x E: a NIAAA workshop on gene-environment interactions. | Gunzerath L et al. | β | 2003 | β |
| High-alcohol-drinking rats exhibit persistent freezing responses to discrete cues following Pavlovian fear conditioning. | Rorick LM et al. | β | 2003 | β |
| Linkage disequilibrium and haplotype analysis between serotonin receptor 1B gene variations and subtypes of alcoholism. | Sinha R et al. | β | 2003 | β |
| Measurement of impulsivity in a hierarchical model of personality traits: implications for substance use. | Acton GS | β | 2003 | β |
| Neither antisocial personality disorder nor antisocial alcoholism is associated with the MAO-A gene in Han Chinese males. | Lu RB et al. | β | 2003 | β |
| NEO PI-R predictors of alcohol use and alcohol-related problems. | Ruiz MA et al. | β | 2003 | β |
| No association between a polymorphism in the promoter region of the MAOA gene with antisocial personality traits in alcoholics. | Koller G et al. | β | 2003 | β |
| Ondansetron reduces mood disturbance among biologically predisposed, alcohol-dependent individuals. | Johnson BA et al. | β | 2003 | β |
| Outcome predictors in substance use disorders. | Ciraulo DA et al. | β | 2003 | β |
| Personality, substance of choice, and polysubstance involvement among substance dependent patients. | Conway KP et al. | β | 2003 | β |
| Pharmacogenomics of alcohol response and addiction. | Enoch MA | β | 2003 | β |
| Pleiotropic effect of a locus on chromosome 4 influencing alcohol drinking and emotional reactivity in rats. | Terenina-Rigaldie E et al. | β | 2003 | β |
| Polymorphisms in the N-methyl-D-aspartate receptor 1 and 2B subunits are associated with alcoholism-related traits. | Wernicke C et al. | β | 2003 | β |
| Relationships between personality and preferred substance and motivations for use among adolescent substance abusers. | Adams JB et al. | β | 2003 | β |
| Reliability of self-reported age of substance involvement onset. | Parra GR et al. | β | 2003 | β |
| Sex-dependent modulation of ethanol consumption in vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) knockout mice. | Hall FS et al. | β | 2003 | β |
| Social influences in motivated drinking among college students. | Hussong AM | β | 2003 | β |
| The intoxicated child. | Solhkhah R | β | 2003 | β |
| The neurobiology and control of anxious states. | Millan MJ | β | 2003 | β |
| The reinforcing properties of alcohol are mediated by GABA(A1) receptors in the ventral pallidum. | June HL et al. | β | 2003 | β |
| The status of serotonin-selective pharmacotherapy in the treatment of alcohol dependence. | Pettinati HM et al. | β | 2003 | β |
| Adolescent substance use disorders and comorbidity. | Simkin DR | β | 2002 | β |
| Adrenocorticotropin and cortisol responses to a naloxone challenge and risk of alcoholism. | Hernandez-Avila CA et al. | β | 2002 | β |
| Age at onset typology in opioid dependent men: an exploratory study. | De B et al. | β | 2002 | β |
| A genotype-controlled analysis of plasma dopamine beta-hydroxylase in healthy and alcoholic subjects: evidence for alcohol-related differences in noradrenergic function. | KΓΆhnke MD et al. | β | 2002 | β |
| Alcoholism and personality. | Mulder RT | β | 2002 | β |
| Alcohol use disorders in primary care: do gender-specific differences exist? | Brienza RS et al. | β | 2002 | β |
| Analysis of monoamine oxidase A (MAOA) promoter polymorphism in Finnish male alcoholics. | Saito T et al. | β | 2002 | β |
| An evaluation of relations among antisocial behavior, psychopathic traits, and alcohol problems in incarcerated men. | Reardon ML et al. | β | 2002 | β |
| Antisocial alcoholism and serotonin-related polymorphisms: association tests. | Hill EM et al. | β | 2002 | β |
| Binge drinking trajectories from adolescence to emerging adulthood in a high-risk sample: predictors and substance abuse outcomes. | Chassin L et al. | β | 2002 | β |
| Co-occurrence of obsessive-compulsive personality traits in young and middle-aged Japanese alcohol-dependent men. | Suzuki K et al. | β | 2002 | β |
| D(2) dopamine receptor (DRD2) polymorphism is associated with severity of alcohol dependence. | Connor JP et al. | β | 2002 | β |
| Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences. | Bechara A et al. | β | 2002 | β |
| Development of substance dependence in two delinquency subgroups and nondelinquents from a male twin sample. | Taylor J et al. | β | 2002 | β |
| Dopamine agonist and antagonist responders as related to types of nicotine craving and facets of extraversion. | Reuter M et al. | β | 2002 | β |
| Drinks of the father: father's maximum number of drinks consumed predicts externalizing disorders, substance use, and substance use disorders in preadolescent and adolescent offspring. | Malone SM et al. | β | 2002 | β |
| Dysregulation of the hypothalamic-pituitary-thyroid axis in alcoholism. | Hermann D et al. | β | 2002 | β |
| Early-onset alcoholism with conduct disorder: go/no go learning deficits, working memory capacity, and personality. | Finn PR et al. | β | 2002 | β |
| Effect of tryptophan depletion on impulsive behavior in men with or without a family history of alcoholism. | Crean J et al. | β | 2002 | β |
| Effects of (+/-) 3,4-methylene-dioxymethamphetamine (ecstasy) on dopamine system function in humans. | Gerra G et al. | β | 2002 | β |
| Estimating two-stage models for genetic influences on alcohol, tobacco or drug use initiation and dependence vulnerability in twin and family data. | Heath AC et al. | β | 2002 | β |
| Evidence for the importance of the human dopamine transporter gene for withdrawal symptomatology of alcoholics in a German population. | Wernicke C et al. | β | 2002 | β |
| Evolutionary underpinnings of excessive alcohol consumption. | Gerald MS et al. | β | 2002 | β |
| Evolution meets biopsychosociality: an analysis of addictive behavior. | Lende DH et al. | β | 2002 | β |
| Genetic contributions to addiction. | Crabbe JC | β | 2002 | β |
| Heart rate and motor-activating effects of orally self-administered ethanol in alcohol-preferring (P) rats. | Bell RL et al. | β | 2002 | β |
| HPA axis function and drug addictive behaviors: insights from studies with Lewis and Fischer 344 inbred rats. | Kosten TA et al. | β | 2002 | β |
| Implications of multifactorial inheritance for identification of genetic mechanisms in major psychiatric disorders. | Nurnberger JI | β | 2002 | β |
| Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor. | Valdez GR et al. | β | 2002 | β |
| Injury among detoxification patients: alcohol users' greater risk. | Rees VW et al. | β | 2002 | β |
| Longitudinal brain metabolic characterization of chronic alcoholics with proton magnetic resonance spectroscopy. | Parks MH et al. | β | 2002 | β |
| Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders. | Hahn MK et al. | β | 2002 | β |
| Motivation, working memory, and decision making: a cognitive-motivational theory of personality vulnerability to alcoholism. | Finn PR | β | 2002 | β |
| Neurodevelopmental liabilities in alcohol dependence: central serotonin and dopamine dysfunction. | Naranjo CA et al. | β | 2002 | β |
| No association of the MAOA gene with alcoholism among Han Chinese males in Taiwan. | Lu RB et al. | β | 2002 | β |
| Personality and the genetic risk for alcohol dependence. | Slutske WS et al. | β | 2002 | β |
| Personality, drug of choice, and comorbid psychopathology among substance abusers. | Conway KP et al. | β | 2002 | β |
| Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference. | Murphy JM et al. | β | 2002 | β |
| Prefrontal volumes in habitually violent subjects with antisocial personality disorder and type 2 alcoholism. | Laakso MP et al. | β | 2002 | β |
| Regional cerebral blood flow and neuropsychological functioning in early and late onset alcoholism. | Demir B et al. | β | 2002 | β |
| Sex differences in psychopathy and antisocial personality disorder. A review and integration. | Cale EM et al. | β | 2002 | β |
| Substance use disorder and personality disorder. | Sher KJ et al. | β | 2002 | β |
| Subtypes for classifying adolescents with marijuana use disorders: construct validity and clinical implications. | Babor TF et al. | β | 2002 | β |
| Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype. | Dick DM et al. | β | 2002 | β |
| Temperament in schizophrenia: a study of the tridimensional personality questionnaire (TPQ). | SzΓΆke A et al. | β | 2002 | β |
| Temporal progression of cocaine dependence symptoms in the US National Comorbidity Survey. | Shaffer HJ et al. | β | 2002 | β |
| The development, evolution and philosophy of a clinical research unit. | Joyce PR | β | 2002 | β |
| The GABA(A) receptor alpha1 subtype in the ventral pallidum regulates alcohol-seeking behaviors. | Harvey SC et al. | β | 2002 | β |
| The heritability of alcohol abuse and dependence: a meta-analysis of behavior genetic research. | Walters GD | β | 2002 | β |
| Tryptophan metabolism in alcoholism. | Badawy AA | β | 2002 | β |
| Validation study of the Japanese version of the Obsessive-Compulsive Drinking Scale. | Tatsuzawa Y et al. | β | 2002 | β |
| WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence: analysis of demographic, behavioral, physiologic, and drinking variables that contribute to dependence and seeking treatment. International Society on Biomedical Research on Alcoholism. | Glanz J et al. | β | 2002 | β |
| Association between 5HT2A receptor gene promoter region polymorphism and eating disorders in Japanese patients. | Nishiguchi N et al. | β | 2001 | β |
| Association study of serotonin transporter gene regulatory region polymorphism and alcoholism. | Matsushita S et al. | β | 2001 | β |
| Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach. | Wang T et al. | β | 2001 | β |
| Auditory P3a deficits in male subjects at high risk for alcoholism. | Hada M et al. | β | 2001 | β |
| Behavior genetic research on gambling and problem gambling: a preliminary meta-analysis of available data. | Walters GD | β | 2001 | β |
| Biological markers for suicidal behavior in alcohol dependence. | Gorwood P | β | 2001 | β |
| Childhood trauma and attempted suicide in alcoholics. | Roy A | β | 2001 | β |
| Chronic daily ethanol and withdrawal: 2. Behavioral changes during prolonged abstinence. | Rasmussen DD et al. | β | 2001 | β |
| Co-morbidity of personality disorders in individuals with substance use disorders. | Verheul R | β | 2001 | β |
| Constraint, alcoholism, and electrodermal response in aversive classical conditioning and mismatch novelty paradigms. | Finn PR et al. | β | 2001 | β |
| Correlates of intimate partner violence among male alcoholic patients. | Murphy CM et al. | β | 2001 | β |
| Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats. | Haile CN et al. | β | 2001 | β |
| Differential expression of diacylglycerol kinase iota and L18A mRNAs in the brains of alcohol-preferring AA and alcohol-avoiding ANA rats. | Sommer W et al. | β | 2001 | β |
| Differential expression of NPY and its receptors in alcohol-preferring AA and alcohol-avoiding ANA rats. | Caberlotto L et al. | β | 2001 | β |
| Differential sensitivity to the anxiolytic effects of ethanol and flunitrazepam in PKCgamma null mutant mice. | Bowers BJ et al. | β | 2001 | β |
| Dopamine D2 receptor gene (DRD2) is associated with alcoholism with conduct disorder. | Lu RB et al. | β | 2001 | β |
| Dopamine receptor imaging in alcohol dependency: should personality traits be taken into account? | Goethals I et al. | β | 2001 | β |
| DRD4 and DAT1 as modifying genes in alcoholism: interaction with novelty seeking on level of alcohol consumption. | Bau CH et al. | β | 2001 | β |
| Genetic-environment analysis of sensitivity and acute tolerance to ethanol in mice. | Reed CL et al. | β | 2001 | β |
| Genetic polymorphisms of the promoter region of dopamine D2 receptor and dopamine transporter genes and alcoholism among four aboriginal groups and Han Chinese in Taiwan. | Chen WJ et al. | β | 2001 | β |
| Heterogeneity in early onset alcoholism suggests a third group of alcoholics. | Bau CH et al. | β | 2001 | β |
| Individual differences in alcohol-induced aggression. A nonhuman-primate model. | Higley JD | β | 2001 | β |
| Integrating disinhibition and learning risk for alcohol use. | McCarthy DM et al. | β | 2001 | β |
| Locomotor-stimulating effects of indirect dopamine agonists are attenuated in Fawn hooded rats independent of postweaning social experience. | Hall FS et al. | β | 2001 | β |
| Maxillofacial injuries associated with domestic violence. | Le BT et al. | β | 2001 | β |
| Natural course of alcohol use disorders from adolescence to young adulthood. | Rohde P et al. | β | 2001 | β |
| No effect of the cortisol-synthesis inhibitor metyrapone on alcohol drinking: a pilot study. | Eriksson M et al. | β | 2001 | β |
| Origins and consequences of age at first drink. I. Associations with substance-use disorders, disinhibitory behavior and psychopathology, and P3 amplitude. | McGue M et al. | β | 2001 | β |
| Overexpression of dopamine D2 receptors reduces alcohol self-administration. | Thanos PK et al. | β | 2001 | β |
| P300, disinhibited personality, and early-onset alcohol problems. | Justus AN et al. | β | 2001 | β |
| Parental alcoholism and co-occurring antisocial behavior: prospective relationships to externalizing behavior problems in their young sons. | Loukas A et al. | β | 2001 | β |
| Preadolescent children of substance-dependent fathers with antisocial personality disorder: psychiatric disorders and problem behaviors. | Moss HB et al. | β | 2001 | β |
| Psychopathy and the posterior hippocampus. | Laakso MP et al. | β | 2001 | β |
| Reliability and discriminant validity of the Type I/II and Type A/B alcoholic subtype classifications in untreated problem drinkers: a test of the Apollonian--Dionysian hypothesis. | Carpenter KM et al. | β | 2001 | β |
| Responsivity and development of tolerance to the motor impairing effects of moderate doses of ethanol in alcohol-preferring (P) and -nonpreferring (NP) rat lines. | Bell RL et al. | β | 2001 | β |
| Risk factors for adolescent substance abuse. | Weinberg NZ | β | 2001 | β |
| Serotonergic dysfunction, negative mood states, and response to alcohol. | Heinz A et al. | β | 2001 | β |
| Serotonergic pathway genes and subtypes of alcoholism: association studies. | Parsian A et al. | β | 2001 | β |
| Sleep abnormalities during abstinence in alcohol-dependent patients. Aetiology and management. | Landolt HP et al. | β | 2001 | β |
| Substance use, substance abuse, and LD among adolescents with a childhood history of ADHD. | Molina BS et al. | β | 2001 | β |
| The genetics of addiction: alcohol-dependence and D3 dopamine receptor gene. | Gorwood P et al. | β | 2001 | β |
| The genetics of alcoholism and alcohol abuse. | Enoch MA et al. | β | 2001 | β |
| The inebri-actometer: a device for measuring the locomotor activity of Drosophila exposed to ethanol vapor. | Parr J et al. | β | 2001 | β |
| The relationship of perceived social support to substance use in offspring of alcoholics. | Averna S et al. | β | 2001 | β |
| Time perspective and early-onset substance use: a model based on stress-coping theory. | Wills TA et al. | β | 2001 | β |
| Addiction and its reward process through polymorphisms of the D2 dopamine receptor gene: a review. | Noble EP | β | 2000 | β |
| Age of onset as a discriminator between alcoholic subtypes in a treatment-seeking outpatient population. | Johnson BA et al. | β | 2000 | β |
| A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory. | Comings DE et al. | β | 2000 | β |
| An assessment of novelty-seeking behavior in alcohol-preferring and nonpreferring rats. | Nowak KL et al. | β | 2000 | β |
| Association analysis of the GABA(A) receptor subunit genes cluster on 5q33-34 and alcohol dependence in a Japanese population. | Loh EW et al. | β | 2000 | β |
| Associations of family environment and individual factors with tobacco, alcohol, and illicit drug use in adolescents. | Challier B et al. | β | 2000 | β |
| A volumetric MRI study of the hippocampus in type 1 and 2 alcoholism. | Laakso MP et al. | β | 2000 | β |
| Characteristics of Japanese alcoholics with inactive aldehyde dehydrogenase: clinical features of alcoholics with ALDH2*2. | Nakamura K et al. | β | 2000 | β |
| Decision-making biases, antisocial personality, and early-onset alcoholism. | Mazas CA et al. | β | 2000 | β |
| Developmental sources of variation in liability to adolescent substance use disorders. | Dawes MA et al. | β | 2000 | β |
| Different sensitivity to ethanol in alcohol-preferring sP and -nonpreferring sNP rats. | Colombo G et al. | β | 2000 | β |
| Early-onset of illicit substance use is associated with greater axis-II comorbidity, not with axis-I comorbidity. | Franken IH et al. | β | 2000 | β |
| Effects of chronic ethanol administration on serotonin metabolism in the various regions of the rat brain. | Uzbay IT et al. | β | 2000 | β |
| Effects of cocaine-induced sensitization on ethanol drinking: sex and strain differences. | Cailhol S et al. | β | 2000 | β |
| Environmental influences on the failure to drink in inbred rats with an ethanol preference. | Adams N et al. | β | 2000 | β |
| Evaluation of an allelic association of the serotonin 5-HT1B G681C polymorphism with antisocial alcoholism in the German population. | Sander T et al. | β | 2000 | β |
| Flavour conditioning and alcohol: a multilevel model of individual differences. | Glautier S et al. | β | 2000 | β |
| Food craving and food "addiction": a critical review of the evidence from a biopsychosocial perspective. | Rogers PJ et al. | β | 2000 | β |
| Functional variant in the DRD2 receptor promoter region and subtypes of alcoholism. | Parsian A et al. | β | 2000 | β |
| Gamma-hydroxybutyric acid in alcohol preference, dependence and withdrawal. | Colombo G et al. | β | 2000 | β |
| Gender differences and similarities in the personality correlates of adolescent alcohol problems. | Martin CS et al. | β | 2000 | β |
| Genetic and environmental influences on behavioral disinhibition. | Young SE et al. | β | 2000 | β |
| Genotype effects on neurodegeneration and neuroadaptation in monoaminergic neurotransmitter systems. | Heinz A et al. | β | 2000 | β |
| Haplotypes at the DRD2 locus and severe alcoholism. | Noble EP et al. | β | 2000 | β |
| Hispanic and Anglo college women's risk factors for substance use and eating disorders. | Pidcock BW et al. | β | 2000 | β |
| Individual differences in mood reactions to d-amphetamine: a test of three personality factors. | Corr PJ et al. | β | 2000 | β |
| Individual differences predictive of drinking to manage anxiety among non-problem drinkers with panic disorder. | Kushner MG et al. | β | 2000 | β |
| Influence of ascertainment strategy on finding sex differences in genetic estimates from twin studies of alcoholism. | Prescott CA et al. | β | 2000 | β |
| Intellectual, cognitive, and academic performance among sons of alcoholics, during the early school years: differences related to subtypes of familial alcoholism. | Poon E et al. | β | 2000 | β |
| Lack of association between the functional variant of the catechol-o-methyltransferase (COMT) gene and early-onset alcoholism associated with severe antisocial behavior. | Hallikainen T et al. | β | 2000 | β |
| Multidimensional subtypes and treatment outcome in first-time DWI offenders. | Ball SA et al. | β | 2000 | β |
| Personality and substance use disorders: a prospective study. | Sher KJ et al. | β | 2000 | β |
| Personality, family history, and alcohol use among older men: the VA Normative Aging Study. | LoCastro J et al. | β | 2000 | β |
| Pharmacogenetics and the serotonin system: initial studies and future directions. | Veenstra-VanderWeele J et al. | β | 2000 | β |
| Pharmacogenetics of alcohol: treatment implications. | Busto UE | β | 2000 | β |
| Possible association between loudness dependence of auditory evoked potentials and tryptophan hydroxylase-alleles in alcoholics. | Preuss UW et al. | β | 2000 | β |
| Premorbid risk factors for alcohol dependence in antisocial personality disorder. | Yoshino A et al. | β | 2000 | β |
| Prospective analysis of comorbidity: tobacco and alcohol use disorders. | Jackson KM et al. | β | 2000 | β |
| Quantitative trait loci affecting ethanol sensitivity in BXD recombinant inbred mice. | Browman KE et al. | β | 2000 | β |
| Rearing experiences and stress-induced plasma cortisol as early risk factors for excessive alcohol consumption in nonhuman primates. | Fahlke C et al. | β | 2000 | β |
| Relationships between age of onset, antisocial history and general psychopathological traits in Japanese alcoholics. | Matsuoka K et al. | β | 2000 | β |
| Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors. | Blum K et al. | β | 2000 | β |
| Role of serotonin and serotonin-selective pharmacotherapy in alcohol dependence. | Pettinati HM et al. | β | 2000 | β |
| Search for the influence of the tyrosine hydroxylase (TCAT)(n) repeat polymorphism on personality traits. | Persson ML et al. | β | 2000 | β |
| Season of birth and substance abuse: findings from a large national sample. | Goldberg AE et al. | β | 2000 | β |
| Sensation seeking and drinking game participation in heavy-drinking college students. | Johnson TJ et al. | β | 2000 | β |
| Serotonin, impulsivity, and alcohol use disorders in the older adolescent: a psychobiological study. | Soloff PH et al. | β | 2000 | β |
| Structures and limits of animal models: examples from alcohol research. | McClearn GE et al. | β | 2000 | β |
| Temperament and character in women with anorexia nervosa. | Klump KL et al. | β | 2000 | β |
| The D(2) dopamine receptor A(1) allele and opioid dependence: association with heroin use and response to methadone treatment. | Lawford BR et al. | β | 2000 | β |
| The DRD2 gene in psychiatric and neurological disorders and its phenotypes. | Noble EP | β | 2000 | β |
| The effects of familial risk, personality, and expectancies on alcohol use and abuse. | Finn PR et al. | β | 2000 | β |
| The HTR1B 861G>C receptor polymorphism among patients suffering from alcoholism, major depression, anxiety disorders and narcolepsy. | Fehr C et al. | β | 2000 | β |
| The TaqI A1 allele of the dopamine D2 receptor gene and alcoholism in Brazil: association and interaction with stress and harm avoidance on severity prediction. | Bau CH et al. | β | 2000 | β |
| Trajectories of concurrent substance use disorders: a developmental, typological approach to comorbidity. | Jackson KM et al. | β | 2000 | β |
| Addictive disorders in adolescents. | Kaminer Y | β | 1999 | β |
| Alcohol and genetics: new animal models. | Browman KE et al. | β | 1999 | β |
| Alcohol and the brain. Pharmacological insights for psychiatrists. | Nutt D | β | 1999 | β |
| Alcoholic typology and season of birth. | Levine ME et al. | β | 1999 | β |
| Allele dose analysis in recombinant inbred strains: a tool for multiple phenotype analysis with implications for quantitative trait loci mapping. | Markel PD et al. | β | 1999 | β |
| A logistic regression extension of the transmission disequilibrium test for continuous traits: application to linkage disequilibrium between alcoholism and the candidate genes DRD2 and ADH3. | Waldman ID et al. | β | 1999 | β |
| A new conceptual paradigm from genetics and psychobiology for the science of mental health. | Cloninger CR | β | 1999 | β |
| Association analysis of a PAX-6 gene promoter-associated polymorphic repeat with alcohol dependence. | Samochowiec J et al. | β | 1999 | β |
| Association analysis of sequence variants of GABA(A) alpha6, beta2, and gamma2 gene cluster and alcohol dependence. | Sander T et al. | β | 1999 | β |
| Association between drinking-related antisocial behavior and a polymorphism in the serotonin transporter gene in a Japanese population. | Ishiguro H et al. | β | 1999 | β |
| Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism. | Samochowiec J et al. | β | 1999 | β |
| Association of low-voltage alpha EEG with a subtype of alcohol use disorders. | Enoch MA et al. | β | 1999 | β |
| Autoradiographic analysis of 5-HT2A binding sites in the brain of Sardinian alcohol-preferring and nonpreferring rats. | Ciccocioppo R et al. | β | 1999 | β |
| Behavioral disinhibition induced by tryptophan depletion in nonalcoholic young men with multigenerational family histories of paternal alcoholism. | LeMarquand DG et al. | β | 1999 | β |
| Behavioral responses to ethanol in rats perinatally exposed to low lead levels. | Virgolini MB et al. | β | 1999 | β |
| Birth cohort differences in features of antisocial alcoholism among men and women. | Stoltenberg SF et al. | β | 1999 | β |
| Child psychopathology risk factors for drug abuse: overview. | Weinberg NZ et al. | β | 1999 | β |
| Cladistic association analysis of Y chromosome effects on alcohol dependence and related personality traits. | Kittles RA et al. | β | 1999 | β |
| Correlates of problem drinking among young Japanese women: personality and early experiences. | Kitamura T et al. | β | 1999 | β |
| Criminal recidivism as a neurobehavioral syndrome. | French AP et al. | β | 1999 | β |
| Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism. | Begleiter H et al. | β | 1999 | β |
| Different behavioral patterns related to alcohol use in rodents: a factor analysis. | Salimov RM | β | 1999 | β |
| Effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. | Rossetti ZL et al. | β | 1999 | β |
| Ethanol impairs saccadic and smooth pursuit eye movements without producing self-reports of sedation. | Holdstock L et al. | β | 1999 | β |
| Examining an affect regulation model of substance abuse in schizophrenia. The role of traits and coping. | Blanchard JJ et al. | β | 1999 | β |
| Exploring the impact of extended phenotype in stratified samples. | Kovac I et al. | β | 1999 | β |
| Factors associated with the development of substance use disorder in depressed adolescents. | Rao U et al. | β | 1999 | β |
| Gamma-vinyl GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine. | Gerasimov MR et al. | β | 1999 | β |
| Genome-wide linkage analysis using genetic variance components of alcohol dependency-associated censored and continuous traits. | Palmer LJ et al. | β | 1999 | β |
| HTR2C Cys23Ser polymorphism in relation to CSF monoamine metabolite concentrations and DSM-III-R psychiatric diagnoses. | Lappalainen J et al. | β | 1999 | β |
| Human chromosomes 11p15 and 4p12 and alcohol dependence: possible association with the GABRB1 gene. | Parsian A et al. | β | 1999 | β |
| Individual risk factors for adolescent substance use. | Swadi H | β | 1999 | β |
| Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism. | Chen CC et al. | β | 1999 | β |
| Involvement of the cyclic AMP-responsive element binding protein gene transcription factor in genetic preference for alcohol drinking behavior. | Pandey SC et al. | β | 1999 | β |
| Lack of association of the dopamine D4 receptor gene polymorphism with alcoholism in a Brazilian population. | Roman T et al. | β | 1999 | β |
| Neural sensitization model for multiple chemical sensitivity: overview of theory and empirical evidence. | Bell IR et al. | β | 1999 | β |
| No association between DRD2 locus and alcoholism after controlling the ADH and ALDH genotypes in Chinese Han population. | Lee JF et al. | β | 1999 | β |
| Oral ethanol self-administration in rhesus monkeys: behavioral and neurochemical correlates. | Vivian JA et al. | β | 1999 | β |
| P300, alcoholism heritability, and stimulus modality. | Polich J et al. | β | 1999 | β |
| Path analysis of P300 amplitude of individuals from families at high and low risk for developing alcoholism. | Hill SY et al. | β | 1999 | β |
| Patterns of ethanol and saccharin intake in P rats under limited-access conditions. | Nowak KL et al. | β | 1999 | β |
| Platelet adenylyl cyclase activity as a biochemical trait marker for predisposition to alcoholism. | Ratsma JE et al. | β | 1999 | β |
| Reasons for drinking in relation to problem drinking behavior in a sample of Japanese high school students. | Yokoyama K et al. | β | 1999 | β |
| Risk factors for injury to women from domestic violence. | Kyriacou DN et al. | β | 1999 | β |
| Serotonergic function in cocaine addicts: prolactin responses to sequential D,L-fenfluramine challenges. | Buydens-Branchey L et al. | β | 1999 | β |
| Sex-based linkage analysis of alcoholism. | Paterson AD et al. | β | 1999 | β |
| Sex differences in the sources of genetic liability to alcohol abuse and dependence in a population-based sample of U.S. twins. | Prescott CA et al. | β | 1999 | β |
| Suicide in adolescents with disruptive disorders. | Renaud J et al. | β | 1999 | β |
| The DRD2Aβallele: a behavioural genetic risk factor in hepatitis C infection of persistent drug abusers. | Lawford B et al. | β | 1999 | β |
| The ongoing quest for sub-typing substance abuse : current status. | Gupta N et al. | β | 1999 | β |
| The Tridimensional Personality Questionnaire as a predictor of relapse in detoxified alcohol dependents. The European Fluvoxamine in Alcoholism Study Group. | Meszaros K et al. | β | 1999 | β |
| The urinary MHPG/creatinine ratio and its relationship to platelet monoamine oxidase activity in abstinent alcoholics. | Farren CK et al. | β | 1999 | β |
| Toward a rational pharmacotherapy of comorbid substance abuse in schizophrenic patients. | Krystal JH et al. | β | 1999 | β |
| Treatment attrition among alcohol-dependent men: is it related to novelty seeking personality traits? | Kravitz HM et al. | β | 1999 | β |
| Voluntary ethanol drinking during the first three postnatal weeks in lines of rats selectively bred for divergent ethanol preference. | McKinzie DL et al. | β | 1999 | β |
| Activity of the adenylyl cyclase in lymphocytes of male alcoholic patients is state dependent. | Szegedi A et al. | β | 1998 | β |
| Adenylyl cyclases and alcohol. | Tabakoff B et al. | β | 1998 | β |
| Adolescent versus adult onset and the development of substance use disorders in males. | Clark DB et al. | β | 1998 | β |
| A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism. | Edenberg HJ et al. | β | 1998 | β |
| A family-based analysis of whether the functional promoter alleles of the serotonin transporter gene HTT affect the risk for alcohol dependence. | Edenberg HJ et al. | β | 1998 | β |
| Alcoholism and emotional reactivity: more heterogeneous film-induced emotional response in newly detoxified alcoholics compared to controls--a preliminary study. | Kornreich C et al. | β | 1998 | β |
| Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil. | Abi-Dargham A et al. | β | 1998 | β |
| An investigation of the co-occurrence of panic and somatization disorders through temperamental variables. | Battaglia M et al. | β | 1998 | β |
| A quantitative trait locus for alcohol consumption in selectively bred rat lines. | Carr LG et al. | β | 1998 | β |
| Association studies of polymorphisms of CYP2E1 gene in alcoholics with cirrhosis, antisocial personality, and normal controls. | Parsian A et al. | β | 1998 | β |
| Axis I and axis II comorbidity in alcohol dependence and the two types of alcoholism. | Driessen M et al. | β | 1998 | β |
| Behavioral outcomes among children of alcoholics during the early and middle childhood years: familial subtype variations. | Puttler LI et al. | β | 1998 | β |
| Brain imaging in alcoholism. | Estruch R et al. | β | 1998 | β |
| Clinical characteristics and disease course of alcoholics with inactive aldehyde dehydrogenase-2. | Murayama M et al. | β | 1998 | β |
| Comparison of the alcohol-preferring P rat to the Wistar rat in behavioral tests of impulsivity and anxiety. | McMillen BA et al. | β | 1998 | β |
| D2 and D4 dopamine receptor polymorphisms and personality. | Noble EP et al. | β | 1998 | β |
| D2 dopamine receptor and GABA(A) receptor beta3 subunit genes and alcoholism. | Noble EP et al. | β | 1998 | β |
| Development of alcohol drinking behavior in rat lines selectively bred for divergent alcohol preference. | McKinzie DL et al. | β | 1998 | β |
| Differential sensitivity to alcohol reinforcement in groups of men at risk for distinct alcoholism subtypes. | Conrod PJ et al. | β | 1998 | β |
| Dopamine release during ethanol drinking in AA rats. | Nurmi M et al. | β | 1998 | β |
| Dopaminergic and serotonergic alterations in the rat brain during ethanol withdrawal: association with behavioral signs. | Uzbay IT et al. | β | 1998 | β |
| Dual diagnosis: a review of etiological theories. | Mueser KT et al. | β | 1998 | β |
| Effects of abstinence and family history for alcoholism on platelet adenylyl cyclase activity. | Menninger JA et al. | β | 1998 | β |
| Ethanol modulates cocaine-induced behavioral change in inbred mice. | Cook MN et al. | β | 1998 | β |
| Executive cognitive functioning in alcohol use disorders. | Giancola PR et al. | β | 1998 | β |
| Extension of a typology of alcohol dependence based on relative genetic and environmental loading. | Johnson EO et al. | β | 1998 | β |
| Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders? | Lesch KP et al. | β | 1998 | β |
| Genetic analysis of diagnostic systems of alcoholism in males. | van den Bree MB et al. | β | 1998 | β |
| Genetic basis of event-related potentials and their relationship to alcoholism and alcohol use. | Porjesz B et al. | β | 1998 | β |
| High ethanol tolerance in young adults is associated with the low-activity variant of the promoter of the human serotonin transporter gene. | TΓΌrker T et al. | β | 1998 | β |
| Individual differences in the biphasic effects of ethanol. | Holdstock L et al. | β | 1998 | β |
| Integrating the cognitive and physiological aspects of craving. | Weinstein A et al. | β | 1998 | β |
| Is a mild deficit in executive functions in boys related to childhood ADHD or to parental multigenerational alcoholism? | Wiers RW et al. | β | 1998 | β |
| Linkage of an alcoholism-related severity phenotype to chromosome 16. | Foroud T et al. | β | 1998 | β |
| Modification of alcohol withdrawal by the A9 allele of the dopamine transporter gene. | Schmidt LG et al. | β | 1998 | β |
| Multivariate genetic analysis of the causes of temperance board registrations. In all Swedish male-male [correction of male-female] twin pairs born 1926-1949. | Kendler KS et al. | β | 1998 | β |
| Overt behavior problems and serotonergic function in middle childhood among male and female offspring of alcoholic fathers. | Twitchell GR et al. | β | 1998 | β |
| P3 scalp topography to target and novel visual stimuli in children of alcoholics. | Van der Stelt O et al. | β | 1998 | β |
| Pathways of risk for accelerated heavy alcohol use among adolescent children of alcoholic parents. | Hussong AM et al. | β | 1998 | β |
| Platelet MAO activity in subtypes of alcoholics and controls in a homogenous population. | Farren CK et al. | β | 1998 | β |
| Platelet monoamine oxidase activity in subgroups of alcoholics and controls: results from the Collaborative Study on the Genetics of Alcoholism. | Anthenelli RM et al. | β | 1998 | β |
| Preference for higher sugar concentrations and Tridimensional Personality Questionnaire scores in alcoholic and nonalcoholic men. | Kampov-Polevoy AB et al. | β | 1998 | β |
| Propylthiouracil tasting as a possible genetic association marker for two types of alcoholism. | DiCarlo ST et al. | β | 1998 | β |
| Psychotherapies for adolescent substance abusers: a pilot study. | Kaminer Y et al. | β | 1998 | β |
| Reduced central serotonin transporters in alcoholism. | Heinz A et al. | β | 1998 | β |
| Role of taste and calories in the selection of ethanol by C57BL/6NHsd and Hsd:ICR mice. | McMillen BA et al. | β | 1998 | β |
| Serotonin transporter gene variants in alcohol-dependent subjects with dissocial personality disorder. | Sander T et al. | β | 1998 | β |
| Social anxiety, alcohol expectancies, and drinking-game participation. | Johnson TJ et al. | β | 1998 | β |
| Social class and substance use disorders: the value of social class as distinct from socioeconomic status. | Wohlfarth T et al. | β | 1998 | β |
| Substance use disorders. Difficulties in diagnoses. | Ross SM et al. | β | 1998 | β |
| Symptoms and characteristics of individuals with different types of recovery from DSM-IV alcohol dependence. | Dawson DA | β | 1998 | β |
| Temperament Style and Substance Abuse Characteristics. | Henderson MJ et al. | β | 1998 | β |
| The D2 dopamine receptor gene: a review of association studies in alcoholism and phenotypes. | Noble EP | β | 1998 | β |
| The fruit fly: a model organism to study the genetics of alcohol abuse and addiction? | Bellen HJ | β | 1998 | β |
| Understanding and preventing substance abuse by adolescents: a guide for primary care clinicians. | Liepman MR et al. | β | 1998 | β |
| Visual and auditory event-related potentials in young children of alcoholics from high- and low-density families. | RodrΓguez HolguΓn S et al. | β | 1998 | β |
| Why different rules are required for polygenic inheritance: lessons from studies of the DRD2 gene. | Comings DE | β | 1998 | β |
| A behavioral-genetic perspective on children of alcoholics. | McGue M | β | 1997 | β |
| A comparison of the symptoms associated with early and late onset alcohol dependence. | Watson CG et al. | β | 1997 | β |
| Acquisition and maintenance of intravenous cocaine self-administration in Lewis and Fischer inbred rat strains. | Kosten TA et al. | β | 1997 | β |
| Alcohol, drugs, and violence in children's lives. | Miller BA et al. | β | 1997 | β |
| Alcoholism in a geriatric outpatient clinic of SΓ£o Paulo-Brazil. | Hirata ES et al. | β | 1997 | β |
| Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium. | Sander T et al. | β | 1997 | β |
| A personality typology of smokers. | Patton D et al. | β | 1997 | β |
| Association of prenatal alcohol exposure with behavioral and learning problems in early adolescence. | Olson HC et al. | β | 1997 | β |
| Association of the D2 dopamine receptor A1 allele with alcoholism: medical severity of alcoholism and type of controls. | Lawford BR et al. | β | 1997 | β |
| Attention deficit hyperactivity disorder (ADHD) is associated with early onset substance use disorders. | Wilens TE et al. | β | 1997 | β |
| Biphasic effects of alcohol on heart rate are influenced by alcoholic family history and rate of alcohol ingestion. | Conrod PJ et al. | β | 1997 | β |
| Catalase and the production of brain acetaldehyde: a possible mediator of the psychopharmacological effects of ethanol. | Smith BR et al. | β | 1997 | β |
| Childhood hyperactivity, gender, and Cloninger's personality dimensions in alcoholics. | Johnson DE et al. | β | 1997 | β |
| Convergent validity of DSM-III-R and DSM-IV alcohol dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. | Grant BF | β | 1997 | β |
| D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects. | Gelernter J et al. | β | 1997 | β |
| Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions. | MΓΆller C et al. | β | 1997 | β |
| Decreased measures of experimental anxiety in rats bred for high alcohol preference. | MΓΆller C et al. | β | 1997 | β |
| Disinhibited personality and sensitivity to alcohol reinforcement: independent correlates of drinking behavior in sons of alcoholics. | Conrod PJ et al. | β | 1997 | β |
| Dopamine D2 receptor gene and alcoholism among four aboriginal groups and Han in Taiwan. | Chen WJ et al. | β | 1997 | β |
| Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics. | Sander T et al. | β | 1997 | β |
| Early onset cannabis use and psychosocial adjustment in young adults. | Fergusson DM et al. | β | 1997 | β |
| E. M. Jellinek and the evolution of alcohol studies: a critical essay. | Page PB | β | 1997 | β |
| Event-related potentials in COA's. | Porjesz B et al. | β | 1997 | β |
| Gender and comorbid psychopathology in adolescents with alcohol dependence. | Clark DB et al. | β | 1997 | β |
| Genetic markers of alcohol abuse. | Ferguson RA et al. | β | 1997 | β |
| Growing up in an alcoholic family system: the effect on anxiety and differentiation of self. | Maynard S | β | 1997 | β |
| Human adenylyl cyclase type 7 contains polymorphic repeats in the 3' untranslated region: investigations of association with alcoholism. | Hellevuo K et al. | β | 1997 | β |
| Human dopamine transporter gene polymorphism (VNTR) and alcoholism. | Parsian A et al. | β | 1997 | β |
| Human GABAA receptor alpha 1 and alpha 3 subunits genes and alcoholism. | Parsian A et al. | β | 1997 | β |
| Human GABA, Receptor Ξ±<sub>l</sub> and Ξ±<sub>3</sub> Subunits Genes and Alcoholism. | Parsian A et al. | β | 1997 | β |
| Integrative psychobiological approach to psychiatric assessment and treatment. | Cloninger CR et al. | β | 1997 | β |
| Is ADHD a risk factor for psychoactive substance use disorders? Findings from a four-year prospective follow-up study. | Biederman J et al. | β | 1997 | β |
| Neuropsychological functioning in sons of active alcoholic, recovering alcoholic, and social drinking fathers. | Ozkaragoz T et al. | β | 1997 | β |
| No association between polymorphisms in the human dopamine D3 and D4 receptors genes and alcoholism. | Parsian A et al. | β | 1997 | β |
| Persistence predicts latency to relapse following inpatient treatment for alcohol dependence. | Cannon DS et al. | β | 1997 | β |
| Persistent alterations in behavior and serotonin activity after recovery from anorexia and bulimia nervosa. | Kaye WH | β | 1997 | β |
| Personality and substance use disorders: I. Effects of gender and alcoholism subtype. | McGue M et al. | β | 1997 | β |
| Personality and Substance Use Disorders: I. Effects of Gender and Alcoholism Subtype. | McGue M et al. | β | 1997 | β |
| Psychological characteristics of children of alcoholics. | Sher KJ | β | 1997 | β |
| Risk-taking behavior in adolescents: the paradigm. | Irwin CE et al. | β | 1997 | β |
| Russian adolescent drug use and comparisons to United States adolescents. | Scheer SD et al. | β | 1997 | β |
| Startle modulation in children at risk for anxiety disorders and/or alcoholism. | Grillon C et al. | β | 1997 | β |
| The moderating effects of children's fear and activity level on relations between parenting practices and childhood symptomatology. | Colder CR et al. | β | 1997 | β |
| The neurobiology of alcoholism in genetically selected rat models. | Stewart RB et al. | β | 1997 | β |
| The relation between alcohol and aggression: an integrated biopsychosocial conceptualization. | Chermack ST et al. | β | 1997 | β |
| Three clusters of male alcoholics. | Hauser J et al. | β | 1997 | β |
| Timing of paternal substance use disorder cessation and effects on problem behaviors in sons. | Moss HB et al. | β | 1997 | β |
| Toward a definition of a valid model of alcoholism: multiple animal models for multiple diseases. | McMillen BA | β | 1997 | β |
| Two types classification of male alcoholism confirmed. | Modestin J et al. | β | 1997 | β |
| Ultrasonic vocalization behavior differs between lines of ethanol-preferring and nonpreferring rats. | Knapp DJ et al. | β | 1997 | β |
| Which relapse criteria best predict the mortality risk of treated alcoholics? | Yoshino A et al. | β | 1997 | β |
| Young adults' drug use: a 17-year longitudinal inquiry of antecedents. | Brook JS et al. | β | 1997 | β |
| A nonhuman primate model of type II alcoholism? Part 2. Diminished social competence and excessive aggression correlates with low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations. | Higley JD et al. | β | 1996 | β |
| A nonhuman primate model of type II excessive alcohol consumption? Part 1. Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations and diminished social competence correlate with excessive alcohol consumption. | Higley JD et al. | β | 1996 | β |
| A prospective study of self-esteem and alcohol use disorders in early adulthood: evidence for gender differences. | Walitzer KS et al. | β | 1996 | β |
| Can we subtype alcoholism? A latent class analysis of data from relatives of alcoholics in a multicenter family study of alcoholism. | Bucholz KK et al. | β | 1996 | β |
| Conference summary: Consensus Conference on Alcohol Dependence and the Role of Pharmacotherapy in its Treatment. | Chick J et al. | β | 1996 | β |
| Effects of the benzodiazepine inverse agonist RO19-4603 alone and in combination with the benzodiazepine receptor antagonists flumazenil, ZK 93426 and CGS 8216, on ethanol intake in alcohol-preferring (P) rats. | June HL et al. | β | 1996 | β |
| Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats. | Weiss F et al. | β | 1996 | β |
| Gender and Alcoholic Subtypes. | Del Boca FK et al. | β | 1996 | β |
| Generalizability of the type A/type B distinction across different psychoactive substances. | Feingold A et al. | β | 1996 | β |
| Illness severity and self-efficacy as course predictors of DSM-IV alcohol dependence in a multisite clinical sample. | Langenbucher J et al. | β | 1996 | β |
| Indicators of genetic and environmental influence in alcohol-dependent individuals. | Johnson EO et al. | β | 1996 | β |
| Indicators of genetic and environmental influences in drug abusing individuals. | Johnson EO et al. | β | 1996 | β |
| No association between alcoholism and multiple polymorphisms at the dopamine D2 receptor gene (DRD2) in three distinct Taiwanese populations. | Lu RB et al. | β | 1996 | β |
| Overview of substance abuse acupuncture treatment research. | Culliton PD et al. | β | 1996 | β |
| Patient factors related to early attrition from an outpatient cocaine research clinic. | Agosti V et al. | β | 1996 | β |
| Pharmacological treatment for antisocial personality disorder alcoholics: a preliminary study. | Penick EC et al. | β | 1996 | β |
| Platelet adenylyl cyclase activity in alcoholics and subtypes of alcoholics. WHO/ISBRA Study Clinical Centers. | Parsian A et al. | β | 1996 | β |
| Prediction of 3-year outcome of treated alcoholics by an empirically derived multivariate typology. | Yoshino A et al. | β | 1996 | β |
| Psychopharmacologic violence associated with cocaine abuse: kindling of a limbic dyscontrol syndrome? | Davis WM | β | 1996 | β |
| Quantitative trait locus gene mapping: a new method for locating alcohol response genes. | Crabbe JC | β | 1996 | β |
| Risk of alcoholism and parental history: gender differences and a possible reporting bias. | Crum RM et al. | β | 1996 | β |
| Serotonin2C receptors and serotonin2C receptor-mediated phosphoinositide hydrolysis in the brain of alcohol-preferring and alcohol-nonpreferring rats. | Pandey SC et al. | β | 1996 | β |
| Substance abuse, comorbidity, and sensation seeking: gender differences. | Scourfield J et al. | β | 1996 | β |
| Subtypes of alcohol-dependent men: a typology based on relative genetic and environmental loading. | Johnson EO et al. | β | 1996 | β |
| Temperament dimensions explain the comorbidity of psychiatric disorders. | Battaglia M et al. | β | 1996 | β |
| The 1996 James B. Isaacson Award Lecture. Platelet MAO activity in type 1/type 2 alcoholics. | von Knorring L | β | 1996 | β |
| The biological, social and clinical bases of drug addiction: commentary and debate. | Altman J et al. | β | 1996 | β |
| The Classification of Alcoholics: Typology Theories From the 19th Century to the Present. | Babor TF | β | 1996 | β |
| The Development of Alcoholic Subtypes: Risk Variation Among Alcoholic Families During the Early Childhood Years. | Zucker RA et al. | β | 1996 | β |
| The relationship between age at onset and comorbidity in psychiatric disorders. | Kasch KL et al. | β | 1996 | β |
| The tridimensional personality model: influencing variables in a sample of detoxified alcohol dependents. European Fluvoxamine in Alcoholism Study Group. | Meszaros K et al. | β | 1996 | β |
| Tridimensional personality traits in sons of alcoholic and nonalcoholic fathers. | Howard MO et al. | β | 1996 | β |
| Type A and Type B Alcoholism: Applicability Across Subpopulations and Treatment Settings. | Ball SA | β | 1996 | β |
| Type I and Type II Alcoholism: An Update. | Cloninger CR et al. | β | 1996 | β |
| Typology Research Questionnaires. | Ingle KG | β | 1996 | β |
| Use of serotonin selective pharmacotherapy in the treatment of alcohol dependence. | Pettinati HM | β | 1996 | β |
| Voices of the afflicted. | Erickson CK | β | 1996 | β |
| Aggressivity in adolescent alcohol abusers: relationship with conduct disorder. | Moss HB et al. | β | 1995 | β |
| Alcohol and adolescents. | Morrison SF et al. | β | 1995 | β |
| Alcoholism in Brazil--the role of personality and susceptibility to stress. | Bau CH et al. | β | 1995 | β |
| Alcoholism: the role of different motivational systems. | Pihl RO et al. | β | 1995 | β |
| Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics. | Tiihonen J et al. | β | 1995 | β |
| An empirical classification of drinking patterns among alcoholics: binge, episodic, sporadic, and steady. | Epstein EE et al. | β | 1995 | β |
| An evaluation of type A and B alcoholics. | Schuckit MA et al. | β | 1995 | β |
| Antisocial tendencies and cortical sensory-evoked responses in alcoholism. | Hegerl U et al. | β | 1995 | β |
| Assessment, diagnosis, and treatment of the dually diagnosed adolescent. | Armentano ME | β | 1995 | β |
| Association and linkage studies of the TAQI A1 allele at the dopamine D2 receptor gene in samples of female and male alcoholics. | Neiswanger K et al. | β | 1995 | β |
| Autonomic reactivity and alcohol-induced dampening in men at risk for alcoholism and men at risk for hypertension. | Conrod PJ et al. | β | 1995 | β |
| Bromocriptine in the treatment of alcoholics with the D2 dopamine receptor A1 allele. | Lawford BR et al. | β | 1995 | β |
| Childhood and adulthood temperament and problem behaviors and adulthood substance use. | Ohannessian CM et al. | β | 1995 | β |
| Classical and neoclassical approaches to the genetic analysis of alcohol-related phenotypes. | Dudek BC et al. | β | 1995 | β |
| Cognitive Impairment in Children of Alcoholics. | Pihl RO et al. | β | 1995 | β |
| Cognitive psychosocial performance and recovery in female alcoholics. | Nixon SJ et al. | β | 1995 | β |
| Common genetic mechanisms in alcohol, drug, and mental disorder comorbidity. | Pickens RW et al. | β | 1995 | β |
| Development of a comprehensive treatment program for chemical dependency at Al Amal Hospital, Dammam. | Abdel-Mawgoud M et al. | β | 1995 | β |
| DSM-III, DSM-IV and ICD-10 as severity scales for drug dependence. | Langenbucher JW et al. | β | 1995 | β |
| Evidence for reduced dopamine D2 receptor sensitivity in postwithdrawal alcoholics. | Farren CK et al. | β | 1995 | β |
| Family history of alcoholism and the mediation of alcohol intake by catalase: further evidence for catalase as a marker of the propensity to ingest alcohol. | Koechling UM et al. | β | 1995 | β |
| Gonadal hormones and aggression-maintaining effect of alcohol in male transgenic transforming growth factor-alpha mice. | Hilakivi-Clarke L et al. | β | 1995 | β |
| Homovanillic acid and dopamine-beta-hydroxylase in male youth: relationships with paternal substance abuse and antisocial behavior. | Gabel S et al. | β | 1995 | β |
| Inheritance of Alcohol Abuse: Cross-Fitting Analysis of Adopted Men. | Heath AC | β | 1995 | β |
| Lack of association between alcohol-dependence and D3 dopamine receptor gene in three independent samples. | Gorwood P et al. | β | 1995 | β |
| Longitudinal patterns of heart rate and fighting behavior in 9- through 12-year-old boys. | Kindlon DJ et al. | β | 1995 | β |
| Loss of control and inability to abstain: the measurement of and the relationship between two constructs in male alcoholics. | Kahler CW et al. | β | 1995 | β |
| Monoamine oxidases and alcoholism. I. Studies in unrelated alcoholics and normal controls. | Parsian A et al. | β | 1995 | β |
| Neuroendocrine support for a relationship between "novelty seeking" and dopaminergic function in alcohol-dependent men. | Wiesbeck GA et al. | β | 1995 | β |
| Pathways into risk: temperament and behavior problems in three- to five-year-old sons of alcoholics. | Jansen RE et al. | β | 1995 | β |
| Perinatal alterations of thyroid hormones and behaviour in adult rats. | Darbra S et al. | β | 1995 | β |
| Personality and EEG beta in older adults with alcoholic relatives. | Pollock VE et al. | β | 1995 | β |
| Personality and the inheritance of smoking behavior: a genetic perspective. | Heath AC et al. | β | 1995 | β |
| Personality antecedents of alcoholism in a national area probability sample. | Cloninger CR et al. | β | 1995 | β |
| Platelet monoamine oxidase activity levels in subgroups of alcoholics: diagnostic, temporal, and clinical correlates. | Anthenelli RM et al. | β | 1995 | β |
| Policy and ethical implications of biosocial research. | Udry JR | β | 1995 | β |
| Primates in Alcohol Research. | Higley JD | β | 1995 | β |
| Psychiatric comorbidity of smoking and nicotine dependence. | Breslau N | β | 1995 | β |
| Psychometric properties of impulsivity measures: temporal stability, validity and factor structure. | Kindlon D et al. | β | 1995 | β |
| Rat mitochondrial aldehyde dehydrogenase polymorphism and major histocompatibility complex RT1.A phenotypes are not associated with alcohol drinking in P and NP rats. | Carr LG et al. | β | 1995 | β |
| Reduced visuospatial performance in children with the D2 dopamine receptor A1 allele. | Berman SM et al. | β | 1995 | β |
| Regional brain metabolic response to lorazepam in subjects at risk for alcoholism. | Volkow ND et al. | β | 1995 | β |
| Sex- and strain-related differences in first-pass alcohol metabolism in mice. | Desroches D et al. | β | 1995 | β |
| Sex differences and the effects of tail pinch on ethanol drinking in Maudsley rats. | Adams N | β | 1995 | β |
| Strategies for mapping and identifying quantitative trait loci specifying behavioral responses to alcohol. | Buck KJ | β | 1995 | β |
| Temperament in eating disorders. | Bulik CM et al. | β | 1995 | β |
| The psychobiological regulation of social cooperation. | Cloninger CR | β | 1995 | β |
| The psychopharmacological basis of nicotine's differential effects on behavior: individual subject variability in the rat. | Rosecrans JA | β | 1995 | β |
| The Search for Biochemical Markers. | Anthenelli RM et al. | β | 1995 | β |
| Thyrotropin and prolactin responses to thyrotropin-releasing hormone in young men at high or low risk for alcoholism. | Garbutt JC et al. | β | 1995 | β |
| Time perspective of substance abuse patients: comparison of the scales in Stanford Time Perspective Inventory, Beck Depression Inventory, and Beck Hopelessness Scale. | Breier-Williford S et al. | β | 1995 | β |
| Correlates of early- and late-onset alcohol dependence. | Varma VK et al. | β | 1994 | β |
| Psychological correlates of frequency and type of drug use among jail inmates. | Fishbein DH et al. | β | 1994 | β |
| Psychological mechanisms of enhanced risk of addiction in children of alcoholics: a dual pathway? | Wiers RW et al. | β | 1994 | β |