Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1.
paper
Cited
Public
Unavailable
- Authors
- Neville, Matt J; Johnstone, Elaine C; Walton, Robert T
- Year
- 2004
- Journal
- Human mutation
- PMID
- 15146457
- DOI
- 10.1002/humu.20039
The dopamine D2 receptor has been extensively studied in relation to alcoholism, substance abuse, and nicotine dependence. The most frequently examined polymorphism linked to this gene is the Taq1A restriction fragment length polymorphism (RFLP) (dbSNP rs1800497; g.32806C>T in GenBank AF050737.1), which has been associated with a reduction in D2 receptor density, although this is not universally accepted. The Taq1A RFLP lies 10 kB downstream of DRD2 and may therefore fall within a different coding region than the DRD2 gene or within a regulatory region. Within this downstream region, we have identified a novel kinase gene, named ankyrin repeat and kinase domain containing 1 (ANKK1), which contains a single serine/threonine kinase domain and is expressed at low levels in placenta and whole spinal cord RNA. This gene is a member of an extensive family of proteins involved in signal transduction pathways. The DRD2 Taq1A RFLP is a single nucleotide polymorphism (SNP) that causes an amino acid substitution within the 11th ankyrin repeat of ANKK1 (p.Glu713Lys), which, while unlikely to affect structural integrity, may affect substrate-binding specificity. If this is the case, then changes in ANKK1 activity may provide an alternative explanation for previously described associations between the DRD2 Taq1A RFLP and neuropsychiatric disorders such as addiction.
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| An association study of <i>Taq1A ANKK1</i> and <i>C957T</i> and -Β <i>141C DRD2</i> polymorphisms in adults with internet gaming disorder: a pilot study. | Paik SH et al. | β | 2017 | β |
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| Association of the dopamine D2 receptor rs1800497 polymorphism and eating behavior in Chilean children. | ObregΓ³n AM et al. | β | 2017 | β |
| Brain on Fire: Incentive Salience, Hedonic Hot Spots, Dopamine, Obesity, and Other Hunger Games. | Cameron JD et al. | β | 2017 | β |
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| DRD2: Bridging the Genome and Ingestive Behavior. | Sun X et al. | β | 2017 | β |
| Genetic Correlates of Spirituality/Religion and Depression: A Study in Offspring and Grandchildren at High and Low Familial Risk for Depression. | Anderson MR et al. | β | 2017 | β |
| Hierarchical investigation of genetic influences on response inhibition in healthy young adults. | Weafer J et al. | β | 2017 | β |
| Imaging genetics in neurodevelopmental psychopathology. | Klein M et al. | β | 2017 | β |
| Parenting and adolescents' psychological adjustment: Longitudinal moderation by adolescents' genetic sensitivity. | Stocker CM et al. | β | 2017 | β |
| Pharmacodynamic genetic polymorphisms affect adverse drug reactions of haloperidol in patients with alcohol-use disorder. | Zastrozhin MS et al. | β | 2017 | β |
| Rare deleterious mutations are associated with disease in bipolar disorder families. | Rao AR et al. | β | 2017 | β |
| The Addiction-Related Protein ANKK1 is Differentially Expressed During the Cell Cycle in Neural Precursors. | EspaΓ±a-Serrano L et al. | β | 2017 | β |
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| Alcohol misuse in emerging adulthood: Association of dopamine and serotonin receptor genes with impulsivity-related cognition. | Leamy TE et al. | β | 2016 | β |
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| FTO gene variant modulates the neural correlates of visual food perception. | KΓΌhn AB et al. | β | 2016 | β |
| Genetic variation and dopamine D2 receptor availability: a systematic review and meta-analysis of human in vivo molecular imaging studies. | Gluskin BS et al. | β | 2016 | β |
| Genetic variation and the D2 dopamine receptor: implications for the treatment of neuropsychiatric disease. | Mickey BJ | β | 2016 | β |
| Influence of Dopaminergic System Genetic Variation and Lifestyle Factors on Excessive Alcohol Consumption. | Celorrio D et al. | β | 2016 | β |
| Interaction between the obesity-risk gene FTO and the dopamine D2 receptor gene ANKK1/TaqIA on insulin sensitivity. | Heni M et al. | β | 2016 | β |
| Longitudinal predictors of cannabis use and dependence in offspring from families at ultra high risk for alcohol dependence and in control families. | Hill SY et al. | β | 2016 | β |
| Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity. | Heinrich A et al. | β | 2016 | β |
| Symmetry symptoms in obsessive-compulsive disorder: clinical and genetic correlates. | Lochner C et al. | β | 2016 | β |
| The Addiction-Related Gene Ankk1 is Oppositely Regulated by D1R- and D2R-Like Dopamine Receptors. | Ponce G et al. | β | 2016 | β |
| The Association Between Genetic Variants in the Dopaminergic System and Posttraumatic Stress Disorder: A Meta-Analysis. | Li L et al. | β | 2016 | β |
| The Association of <i>DRD2</i> with Insight Problem Solving. | Zhang S et al. | β | 2016 | β |
| The neurobiological basis of binge-eating disorder. | Kessler RM et al. | β | 2016 | β |
| To quit or not: Vulnerability of women to smoking tobacco. | Park SJ et al. | β | 2016 | β |
| Varenicline in Autism: Theory and Case Report of Clinical and Biochemical Changes. | Mostafavi M et al. | β | 2016 | β |
| Variants in the DRD2 locus and antipsychotic-related prolactin levels: A meta-analysis. | Miura I et al. | β | 2016 | β |
| What does addiction medicine expect from neuroscience? From genes and neurons to treatment responses. | Le Foll B | β | 2016 | β |
| Allelic Variation of Risk for Anxiety Symptoms Moderates the Relation Between Adolescent Safety Behaviors and Social Anxiety Symptoms. | Thomas SA et al. | β | 2015 | β |
| Alterations of Dopamine D2 Receptors and Related Receptor-Interacting Proteins in Schizophrenia: The Pivotal Position of Dopamine Supersensitivity Psychosis in Treatment-Resistant Schizophrenia. | Oda Y et al. | β | 2015 | β |
| An Obesity-Predisposing Variant of the FTO Gene Regulates D2R-Dependent Reward Learning. | Sevgi M et al. | β | 2015 | β |
| A Population Based Study of the Genetic Association between Catecholamine Gene Variants and Spontaneous Low-Frequency Fluctuations in Reaction Time. | Bastiaansen JA et al. | β | 2015 | β |
| A review of pharmacogenetic studies of substance-related disorders. | Jones JD et al. | β | 2015 | β |
| A Shared Molecular and Genetic Basis for Food and Drug Addiction: Overcoming Hypodopaminergic Trait/State by Incorporating Dopamine Agonistic Therapy in Psychiatry. | Gold MS et al. | β | 2015 | β |
| Association between ANKK1 (rs1800497) polymorphism of DRD2 gene and attention deficit hyperactivity disorder: a meta-analysis. | Pan YQ et al. | β | 2015 | β |
| Association between Dopamine Receptor D2 (DRD2) Variations rs6277 and rs1800497 and Cognitive Performance According to Risk Type for Psychosis: A Nested Case Control Study in a Finnish Population Sample. | Ramsay H et al. | β | 2015 | β |
| Association between DRD2/ANKK1 TaqIA polymorphism and common illicit drug dependence: evidence from a meta-analysis. | Deng XD et al. | β | 2015 | β |
| Association between DRD2 (rs1799732 and rs1801028) and ANKK1 (rs1800497) polymorphisms and schizophrenia: a meta-analysis. | Yao J et al. | β | 2015 | β |
| Association between the traditional Chinese medicine pathological factors of opioid addiction and DRD2/ANKK1 TaqIA polymorphisms. | Cai M et al. | β | 2015 | β |
| Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury. | Yue JK et al. | β | 2015 | β |
| Association of Genetic Factors and Gene-Environment Interactions With Risk of Developing Posttraumatic Stress Disorder in a Case-Control Study. | Tian Y et al. | β | 2015 | β |
| Candidate gene-environment interaction research: reflections and recommendations. | Dick DM et al. | β | 2015 | β |
| Commonly-occurring polymorphisms in the COMT, DRD1 and DRD2 genes influence different aspects of motor sequence learning in humans. | Baetu I et al. | β | 2015 | β |
| Common single nucleotide variants underlying drug addiction: more than a decade of research. | BΓΌhler KM et al. | β | 2015 | β |
| CYP2B6 rs2279343 polymorphism is associated with smoking cessation success in bupropion therapy. | Tomaz PR et al. | β | 2015 | β |
| DRD2 and DRD4 genes related to cognitive deficits in HIV-infected adults who abuse alcohol. | Villalba K et al. | β | 2015 | β |
| DRD2 genotypic and haplotype variation is associated with improvements in negative symptoms after 6 weeks' amisulpride treatment. | Kang SG et al. | β | 2015 | β |
| DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson's disease patients. | Zainal Abidin S et al. | β | 2015 | β |
| Mesocorticolimbic dopamine functioning in primary psychopathy:Β A source of within-group heterogeneity. | Yildirim BO et al. | β | 2015 | β |
| Moderating Effects of Genetic Polymorphisms on Improvements in Cognitive Impairment in Breast Cancer Survivors Participating in a 6-Week Mindfulness-Based Stress Reduction Program. | Lengacher CA et al. | β | 2015 | β |
| NCAM1-TTC12-ANKK1-DRD2 gene cluster and the clinical and genetic heterogeneity of adults with ADHD. | Mota NR et al. | β | 2015 | β |
| NCAM1-TTC12-ANKK1-DRD2 variants and smoking motives as intermediate phenotypes for nicotine dependence. | Bidwell LC et al. | β | 2015 | β |
| Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity. | Val-Laillet D et al. | β | 2015 | β |
| Pharmacogenetic considerations in the treatment of Parkinson's disease. | Kurzawski M et al. | β | 2015 | β |
| Pharmacogenetics of drug response in Parkinson's disease. | DΕΎoljiΔ E et al. | β | 2015 | β |
| Pharmacogenetics of nicotine and associated smoking behaviors. | Tanner JA et al. | β | 2015 | β |
| Pharmacotherapy for alcohol dependence: A stratified approach. | Thompson A et al. | β | 2015 | β |
| Posttraumatic Brain Injury Cognitive Performance Is Moderated by Variation Within ANKK1 and DRD2 Genes. | Failla MD et al. | β | 2015 | β |
| Post-Traumatic Brain Injury: Genetic Susceptibility to Outcome. | Davidson J et al. | β | 2015 | β |
| Reward Region Responsivity Predicts Future Weight Gain and Moderating Effects of the TaqIA Allele. | Stice E et al. | β | 2015 | β |
| The addiction-related gene ANKK1 in Parkinsonian patients with impulse control disorder. | Hoenicka J et al. | β | 2015 | β |
| The ANKK1/DRD2 locus is a genomic substrate for affective priming and recognition of angry faces. | Koeneke A et al. | β | 2015 | β |
| The associations among the dopamine D2 receptor Taq1, emotional intelligence, creative potential measured by divergent thinking, and motivational state and these associations' sex differences. | Takeuchi H et al. | β | 2015 | β |
| The pharmacogenetics of alcohol use disorder. | Jones JD et al. | β | 2015 | β |
| Underlying Mechanisms of Gene-Environment Interactions in Externalizing Behavior: A Systematic Review and Search for Theoretical Mechanisms. | Weeland J et al. | β | 2015 | β |
| Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions. | Ma Y et al. | β | 2015 | β |
| Addicted to palatable foods: comparing the neurobiology of Bulimia Nervosa to that of drug addiction. | Hadad NA et al. | β | 2014 | β |
| Alcohol abuse and HIV infection: role of DRD2. | Agudelo M et al. | β | 2014 | β |
| Association of dopamine receptor D2 TaqI A polymorphism and cannabis use disorder in Lagos, Nigeria. | Adedeji OH et al. | β | 2014 | β |
| Association study between the Taq1A (rs1800497) polymorphism and schizophrenia in a Brazilian sample. | Cordeiro Q et al. | β | 2014 | β |
| A variant in ANKK1 modulates acute subjective effects of cocaine: a preliminary study. | Spellicy CJ et al. | β | 2014 | β |
| Different trajectories of adolescent alcohol use: testing gene-environment interactions. | van der Zwaluw CS et al. | β | 2014 | β |
| Dopamine DRD2/ANKK1 Taq1A and DAT1 VNTR polymorphisms are associated with a cognitive flexibility profile in pathological gamblers. | Fagundo AB et al. | β | 2014 | β |
| Dopamine system genes are associated with orienting bias among healthy individuals. | Zozulinsky P et al. | β | 2014 | β |
| DRD2/ANKK1 polymorphism modulates the effect of ventral striatal activation on working memory performance. | Nymberg C et al. | β | 2014 | β |
| Elevated postmortem striatal t-DARPP expression in schizophrenia and associations with DRD2/ANKK1 polymorphism. | Kunii Y et al. | β | 2014 | β |
| Gender-specific association of the SLC6A4 and DRD2 gene variants in bipolar disorder. | Wang TY et al. | β | 2014 | β |
| Genetic Addiction Risk Score (GARS): molecular neurogenetic evidence for predisposition to Reward Deficiency Syndrome (RDS). | Blum K et al. | β | 2014 | β |
| Genetic influence of dopamine receptor, dopamine transporter, and nicotine metabolism on smoking cessation and nicotine dependence in a Japanese population. | Ohmoto M et al. | β | 2014 | β |
| Genetics of alcohol dependence: a review of clinical studies. | Samochowiec J et al. | β | 2014 | β |
| Genetics of Opioid Dependence: A Review of the Genetic Contribution to Opioid Dependence. | Mistry CJ et al. | β | 2014 | β |
| Hypothesizing dopaminergic genetic antecedents in schizophrenia and substance seeking behavior. | Blum K et al. | β | 2014 | β |
| Identification of ANKK1 rs1800497 variant in schizophrenia: new data and meta-analysis. | Zhang C et al. | β | 2014 | β |
| Lack of association between DRD2 and OPRM1 genotypes and adiposity. | Hardman CA et al. | β | 2014 | β |
| Moderator effects of working memory on the stability of ADHD symptoms by dopamine receptor gene polymorphisms during development. | Trampush JW et al. | β | 2014 | β |
| Neurotransmitters in alcoholism: A review of neurobiological and genetic studies. | Banerjee N | β | 2014 | β |
| Parkinson's disease pharmacogenomics: new findings and perspectives. | Schumacher-Schuh AF et al. | β | 2014 | β |
| Polymorphisms in genes encoding dopamine signalling pathway and risk of alcohol dependence: a systematic review. | Bhaskar LV et al. | β | 2014 | β |
| Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility. | Guigas B et al. | β | 2014 | β |
| Suicidal behavior and haplotypes of the dopamine receptor gene (DRD2) and ANKK1 gene polymorphisms in patients with alcohol dependence--preliminary report. | Jasiewicz A et al. | β | 2014 | β |
| The dopaminergic reward system and leisure time exercise behavior: a candidate allele study. | Huppertz C et al. | β | 2014 | β |
| The longitudinal and interactive effects of HIV status, stimulant use, and host genotype upon neurocognitive functioning. | Levine AJ et al. | β | 2014 | β |
| The role of gene-gene interaction in the prediction of criminal behavior. | Boutwell BB et al. | β | 2014 | β |
| Time perception networks and cognition in schizophrenia: a review and a proposal. | GΓ³mez J et al. | β | 2014 | β |
| Towards the clinical implementation of pharmacogenetics in bipolar disorder. | Salloum NC et al. | β | 2014 | β |
| Valenced action/inhibition learning in humans is modulated by a genetic variant linked to dopamine D2 receptor expression. | Richter A et al. | β | 2014 | β |
| Who gains? Genetic and neurophysiological correlates of BMI gain upon college entry in women. | Bauer LO | β | 2014 | β |
| A large-scale meta-analysis of the association between the ANKK1/DRD2 Taq1A polymorphism and alcohol dependence. | Wang F et al. | β | 2013 | β |
| Analysis of the canine brain transcriptome with an emphasis on the hypothalamus and cerebral cortex. | Roy M et al. | β | 2013 | β |
| ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse. | Spellicy CJ et al. | β | 2013 | β |
| A pilot study of genetic variants in dopamine regulators with indoor tanning and melanoma. | Flores KG et al. | β | 2013 | β |
| Association between dopamine receptor 2 TaqIA polymorphisms and smoking behavior with an influence of ethnicity: a systematic review and meta-analysis update. | Ohmoto M et al. | β | 2013 | β |
| Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction. | Levran O et al. | β | 2013 | β |
| COMT and ANKK1-Taq-Ia genetic polymorphisms influence visual working memory. | Berryhill ME et al. | β | 2013 | β |
| Dopamine Genetics and Function in Food and Substance Abuse. | Blum K et al. | β | 2013 | β |
| Dopamine receptor (D4) polymorphism is related to comorbidity between marijuana abuse and depression. | Bobadilla L et al. | β | 2013 | β |
| DRD2 and ANKK1 gene polymorphisms and alcohol dependence: a case-control study among a Mendelian population of East Asian ancestry. | Suraj Singh H et al. | β | 2013 | β |
| DRD2/ANKK1 Taq1A (rs 1800497 C>T) genotypes are associated with susceptibility to second generation antipsychotic-induced akathisia. | Lawford BR et al. | β | 2013 | β |
| Effects of nicotine on emotional distraction of attentional orienting: evidence of possible moderation by dopamine type 2 receptor genotype. | Hammersley JJ et al. | β | 2013 | β |
| Genetics of impulse control disorders in Parkinson's disease. | Cormier F et al. | β | 2013 | β |
| Genetic variation and the risk of haloperidol-related parkinsonism in elderly patients: a candidate gene approach. | Knol W et al. | β | 2013 | β |
| Genetic variations in COMT and DRD2 modulate attentional bias for affective facial expressions. | Gong P et al. | β | 2013 | β |
| Identification of a novel ANKK1 and other dopaminergic (DRD2 and DBH) gene variants in migraine susceptibility. | Ghosh J et al. | β | 2013 | β |
| Influence of ANKK1 and DRD2 polymorphisms in response to haloperidol. | Giegling I et al. | β | 2013 | β |
| Integrating behavioral economics and behavioral genetics: delayed reward discounting as an endophenotype for addictive disorders. | MacKillop J | β | 2013 | β |
| Interaction of the TaqIA polymorphism and poor parental socialization on changes in adolescent marijuana use. | Vaske J | β | 2013 | β |
| Linguistic grammar learning and DRD2-TAQ-IA polymorphism. | Wong PC et al. | β | 2013 | β |
| Motivational salience and genetic variability of dopamine D2 receptor expression interact in the modulation of interference processing. | Richter A et al. | β | 2013 | β |
| Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence. | Vereczkei A et al. | β | 2013 | β |
| Oxytocin receptor gene (OXTR) in relation to loneliness in adolescence: interactions with sex, parental support, and DRD2 and 5-HTTLPR genotypes. | van Roekel E et al. | β | 2013 | β |
| Pathological gambling in Parkinson's disease. A comprehensive review. | Santangelo G et al. | β | 2013 | β |
| Pharmacogenetics of Parkinson's disease - through mechanisms of drug actions. | DroΕΊdzik M et al. | β | 2013 | β |
| Phenotype and micro-array characterization of duplication 11q22.1-q25 and review of the literature. | Ben-Abdallah-Bouhjar I et al. | β | 2013 | β |
| The association between DRD2/ANKK1 and genetically informed measures of alcohol use and problems. | Meyers JL et al. | β | 2013 | β |
| The CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers. | Robinson JD et al. | β | 2013 | β |
| The influence of dopaminergic gene variants on decision making in the ultimatum game. | Reuter M et al. | β | 2013 | β |
| The TaqIA RFLP is associated with attenuated intervention-induced body weight loss and increased carbohydrate intake in post-menopausal obese women. | Cameron JD et al. | β | 2013 | β |
| Ventromedial prefrontal cortex response to concentrated sucrose reflects liking rather than sweet quality coding. | Rudenga KJ et al. | β | 2013 | β |
| A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD. | Jain M et al. | β | 2012 | β |
| A DRD2 and ANKK1 haplotype is associated with nicotine dependence. | Voisey J et al. | β | 2012 | β |
| An association study on the polymorphisms of dopaminergic genes with working memory in a healthy Chinese Han population. | Gong P et al. | β | 2012 | β |
| Assessment between Dopamine Receptor D2 (DRD2) Polymorphisms and Schizophrenia in Korean Population. | Cho AR et al. | β | 2012 | β |
| Association between the dopamine D2 receptor (DRD2) polymorphism and the personality traits of healthy Japanese participants. | Tsuchimine S et al. | β | 2012 | β |
| Dopamine genes (DRD2/ANKK1-TaqA1 and DRD4-7R) and executive function: their interaction with obesity. | Ariza M et al. | β | 2012 | β |
| Dopaminergic system genes in childhood aggression: possible role for DRD2. | Zai CC et al. | β | 2012 | β |
| DRD2 C957T and TaqIA genotyping reveals gender effects and unique low-risk and high-risk genotypes in alcohol dependence. | Swagell CD et al. | β | 2012 | β |
| DRD2 haplotype is associated with dyskinesia induced by levodopa therapy in Parkinson's disease patients. | Rieck M et al. | β | 2012 | β |
| Effects of aripiprazole and the Taq1A polymorphism in the dopamine D2 receptor gene on the clinical response and plasma monoamine metabolites level during the acute phase of schizophrenia. | Miura I et al. | β | 2012 | β |
| Evocative gene-parenting correlations and academic performance at first grade: an exploratory study. | Propper CB et al. | β | 2012 | β |
| Genetic factors modulating the response to stimulant drugs in humans. | Hart AB et al. | β | 2012 | β |
| Genetics of dopamine receptors and drug addiction. | Gorwood P et al. | β | 2012 | β |
| Influence of DRD2 and ANKK1 polymorphisms on the manifestation of withdrawal syndrome symptoms in alcohol addiction. | Grzywacz A et al. | β | 2012 | β |
| Interaction between ALDH2*1*1 and DRD2/ANKK1 TaqI A1A1 genes may be associated with antisocial personality disorder not co-morbid with alcoholism. | Lu RB et al. | β | 2012 | β |
| Linking dopamine neurotransmission and neurogenesis: The evolutionary history of the NTAD (NCAM1-TTC12-ANKK1-DRD2) gene cluster. | Mota NR et al. | β | 2012 | β |
| Missense substitutions associated with behavioural disturbances in Alzheimer's disease (AD). | Proitsi P et al. | β | 2012 | β |
| Multilocus genetic composite reflecting dopamine signaling capacity predicts reward circuitry responsivity. | Stice E et al. | β | 2012 | β |
| Role of genetic polymorphisms of the dopaminergic system in Parkinson's disease patients with impulse control disorders. | Vallelunga A et al. | β | 2012 | β |
| Systematic analysis of dopamine receptor genes (DRD1-DRD5) in antipsychotic-induced weight gain. | MΓΌller DJ et al. | β | 2012 | β |
| The influence of five monoamine genes on trajectories of depressive symptoms across adolescence and young adulthood. | Adkins DE et al. | β | 2012 | β |
| The moderating effect of alcohol-specific parental rule-setting on the relation between the dopamine D2 receptor gene (DRD2), the ΞΌ-opioid receptor gene (OPRM1) and alcohol use in young adolescents. | Pieters S et al. | β | 2012 | β |
| The role of ANKK1 and TTC12 genes on drinking behaviour in tobacco dependent subjects. | Lobo DS et al. | β | 2012 | β |
| Addictive genes and the relationship to obesity and inflammation. | Heber D et al. | β | 2011 | β |
| A Nested Allele-Specific Multiplex Polymerase Chain Reaction Method for the Detection of DRD2 Polymorphisms. | Zahari Z et al. | β | 2011 | β |
| ANKK1/DRD2 locus variants are associated with rimonabant efficacy in aiding smoking cessation: pilot data. | Wilcox CS et al. | β | 2011 | β |
| A review on experimental and clinical genetic associations studies on fear conditioning, extinction and cognitive-behavioral treatment. | Lonsdorf TB et al. | β | 2011 | β |
| Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium. | McGuire V et al. | β | 2011 | β |
| Association study of candidate gene polymorphisms and obesity in a young Mexican-American population from South Texas. | Duran-Gonzalez J et al. | β | 2011 | β |
| Attention-deficit/hyperactivity disorder: is it time to reappraise the role of sugar consumption? | Johnson RJ et al. | β | 2011 | β |
| COMT and ANKK1 gene-gene interaction modulates contextual updating of mental representations. | Garcia-Garcia M et al. | β | 2011 | β |
| COMT Val158Met Genotype and Individual Differences in Executive Function in Healthy Adults. | Wishart HA et al. | β | 2011 | β |
| Do alcohol-dependent individuals with DRD2 A1 allele have an increased risk of relapse? A pilot study. | Dahlgren A et al. | β | 2011 | β |
| DRD2 Taq1A polymorphism modulates prolactin secretion induced by atypical antipsychotics in healthy volunteers. | LΓ³pez-RodrΓguez R et al. | β | 2011 | β |
| Generational association studies of dopaminergic genes in reward deficiency syndrome (RDS) subjects: selecting appropriate phenotypes for reward dependence behaviors. | Blum K et al. | β | 2011 | β |
| Genetic factors of reaction time performance: DRD4 7-repeat allele associated with slower responses. | Szekely A et al. | β | 2011 | β |
| Genetics of alcohol dependence. | Kimura M et al. | β | 2011 | β |
| Genetics of antipsychotic-induced side effects and agranulocytosis. | Chowdhury NI et al. | β | 2011 | β |
| Genetics of eating behavior: established and emerging concepts. | Grimm ER et al. | β | 2011 | β |
| Impulse control disorders in Parkinson's disease: seeking a roadmap toward a better understanding. | Cilia R et al. | β | 2011 | β |
| Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD). | Hack LM et al. | β | 2011 | β |
| Pharmacogenetics of smoking cessation in general practice: results from the patch II and patch in practice trials. | David SP et al. | β | 2011 | β |
| Pharmacological treatment and the prospect of pharmacogenetics in Parkinson's disease. | Kalinderi K et al. | β | 2011 | β |
| PharmGKB summary: dopamine receptor D2. | Mi H et al. | β | 2011 | β |
| Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood. | Nemoda Z et al. | β | 2011 | β |
| Reward mechanisms in obesity: new insights and future directions. | Kenny PJ | β | 2011 | β |
| Risky alcohol use in adolescence: the role of genetics (DRD2, SLC6A4) and coping motives. | van der Zwaluw CS et al. | β | 2011 | β |
| The ANKK1 protein associated with addictions has nuclear and cytoplasmic localization and shows a differential response of Ala239Thr to apomorphine. | Garrido E et al. | β | 2011 | β |
| The influence of gene-environment interactions on alcohol consumption and alcohol use disorders: a comprehensive review. | Young-Wolff KC et al. | β | 2011 | β |
| The influence of three genes on whether adolescents use contraception, USA 1994-2002. | Daw J et al. | β | 2011 | β |
| The role of dopamine transporter (SLC6A3) and dopamine D2 receptor/ankyrin repeat and kinase domain containing 1 (DRD2/ANKK1) gene polymorphisms in personality traits. | Kazantseva A et al. | β | 2011 | β |
| Treatment for tobacco dependence: a potential application for stratified medicine? | Brock AJ et al. | β | 2011 | β |
| Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists. | Ali SF et al. | β | 2011 | β |
| Variability in reward responsivity and obesity: evidence from brain imaging studies. | Burger KS et al. | β | 2011 | β |
| Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients. | Nemoda Z et al. | β | 2010 | β |
| Association of functional variants in the dopamine D2-like receptors with risk for gambling behaviour in healthy Caucasian subjects. | Lobo DS et al. | β | 2010 | β |
| Comparison of DRD2 rs1800497 (TaqIA) polymorphism between schizophrenic patients and healthy controls: Lack of association in a Turkish sample. | Aslan S et al. | β | 2010 | β |
| D2 receptor genetic variation and clinical response to antipsychotic drug treatment: a meta-analysis. | Zhang JP et al. | β | 2010 | β |
| Depression and the role of genes involved in dopamine metabolism and signalling. | Opmeer EM et al. | β | 2010 | β |
| Developmental changes in dopamine neurotransmission in adolescence: behavioral implications and issues in assessment. | Wahlstrom D et al. | β | 2010 | β |
| Dopamine D2 receptor genotype is associated with increased mortality at a 10-year follow-up of alcohol-dependent individuals. | Berggren U et al. | β | 2010 | β |
| Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study. | Prasad P et al. | β | 2010 | β |
| Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. | Johnson PM et al. | β | 2010 | β |
| Epistasis of the DRD2/ANKK1 Taq Ia and the BDNF Val66Met polymorphism impacts novelty seeking and harm avoidance. | Montag C et al. | β | 2010 | β |
| Genetically determined differences in brain response to a primary food reward. | Felsted JA et al. | β | 2010 | β |
| Genetic associations of brain structural networks in schizophrenia: a preliminary study. | Jagannathan K et al. | β | 2010 | β |
| Genetic association studies of performance monitoring and learning from feedback: the role of dopamine and serotonin. | Ullsperger M | β | 2010 | β |
| Genetic, personality, and environmental predictors of drug use in adolescents. | Conner BT et al. | β | 2010 | β |
| Genetic variation in three candidate genes and nicotine dependence, withdrawal and smoking cessation in hospitalized patients. | De Ruyck K et al. | β | 2010 | β |
| Influence of DRD2 and ANKK1 genotypes on apomorphine-induced growth hormone (GH) response in alcohol-dependent patients. | Lucht M et al. | β | 2010 | β |
| Neurobehavioral evidence for changes in dopamine system activity during adolescence. | Wahlstrom D et al. | β | 2010 | β |
| Pharmacogenetics of alcohol and alcohol dependence treatment. | Kranzler HR et al. | β | 2010 | β |
| Pharmacogenetics of D2 dopamine receptor gene in prolactin-secreting pituitary adenomas. | Filopanti M et al. | β | 2010 | β |
| Pharmacogenetics of drug dependence: role of gene variations in susceptibility and treatment. | Khokhar JY et al. | β | 2010 | β |
| Pharmacogenetics of smoking cessation therapy. | Kortmann GL et al. | β | 2010 | β |
| Pharmacogenomic implications of variants of monoaminergic-related genes in geriatric psychiatry. | Shiroma PR et al. | β | 2010 | β |
| Polymorphisms in dopamine system genes are associated with individual differences in attention in infancy. | Holmboe K et al. | β | 2010 | β |
| Population-based case-control study of DRD2 gene polymorphisms and alcoholism. | Bhaskar LV et al. | β | 2010 | β |
| Review: The biological basis of antipsychotic response in schizophrenia. | Stone JM et al. | β | 2010 | β |
| Reward circuitry responsivity to food predicts future increases in body mass: moderating effects of DRD2 and DRD4. | Stice E et al. | β | 2010 | β |
| Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans. | David SP et al. | β | 2010 | β |
| The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine. | Hoenicka J et al. | β | 2010 | β |
| The D2 dopamine receptor gene and nicotine dependence among bladder cancer patients and controls. | Clague J et al. | β | 2010 | β |
| The D2 dopamine receptor gene variant C957T affects human fear conditioning and aversive priming. | Huertas E et al. | β | 2010 | β |
| Waterpipe Smoking And The DRD2/ANKK1 Genotype. | Radwan GN et al. | β | 2010 | β |
| Association of DRD3 and GRIN2B with impulse control and related behaviors in Parkinson's disease. | Lee JY et al. | β | 2009 | β |
| Association of the dopamine D2 receptor gene with alcohol dependence: haplotypes and subgroups of alcoholics as key factors for understanding receptor function. | Kraschewski A et al. | β | 2009 | β |
| Association of the DRD2 and DRD3 polymorphisms with response to pramipexole in Parkinson's disease patients. | Liu YZ et al. | β | 2009 | β |
| Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new data. | MunafΓ² MR et al. | β | 2009 | β |
| C957T polymorphism of dopamine D2 receptor gene affects striatal DRD2 in vivo availability by changing the receptor affinity. | Hirvonen MM et al. | β | 2009 | β |
| C957T polymorphism of the human dopamine D2 receptor gene predicts extrastriatal dopamine receptor availability in vivo. | Hirvonen MM et al. | β | 2009 | β |
| Candidate genes for cannabis use disorders: findings, challenges and directions. | Agrawal A et al. | β | 2009 | β |
| Candidate gene studies of ADHD: a meta-analytic review. | Gizer IR et al. | β | 2009 | β |
| Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population. | Betcheva ET et al. | β | 2009 | β |
| Clinical and pharmacogenetic determinants for the discontinuation of non-ergoline dopamine agonists in Parkinson's disease. | Arbouw ME et al. | β | 2009 | β |
| Cortical NMDA receptor expression in human chronic alcoholism: influence of the TaqIA allele of ANKK1. | Ridge JP et al. | β | 2009 | β |
| D2 dopamine receptor Taq1A polymorphism, body weight, and dietary intake in type 2 diabetes. | Barnard ND et al. | β | 2009 | β |
| Differential effects of 5-HTTLPR and DRD2/ANKK1 polymorphisms on electrocortical measures of error and feedback processing in children. | Althaus M et al. | β | 2009 | β |
| Dopamine DRD2 polymorphism alters reversal learning and associated neural activity. | Jocham G et al. | β | 2009 | β |
| Dopamine for "wanting" and opioids for "liking": a comparison of obese adults with and without binge eating. | Davis CA et al. | β | 2009 | β |
| DRD2-related TaqIA polymorphism modulates motivation to smoke. | Zuo Y et al. | β | 2009 | β |
| Effect of the TaqIA polymorphism on ethanol response in the brain. | London ED et al. | β | 2009 | β |
| Effects of DRD2/ANKK1 gene variations and clinical factors on aripiprazole efficacy in schizophrenic patients. | Shen YC et al. | β | 2009 | β |
| Gene-environment interactions across development: Exploring DRD2 genotype and prenatal smoking effects on self-regulation. | Wiebe SA et al. | β | 2009 | β |
| Genetic aspects of pathological gambling: a complex disorder with shared genetic vulnerabilities. | Lobo DS et al. | β | 2009 | β |
| Genetic diagnostics of functional variants of the human dopamine D2 receptor gene. | Doehring A et al. | β | 2009 | β |
| Genetic linkage findings for DSM-IV nicotine withdrawal in two populations. | Pergadia ML et al. | β | 2009 | β |
| Genetic modulation of the pharmacological treatment of pain. | LΓΆtsch J et al. | β | 2009 | β |
| Genetics of alcohol dependence. | Gelernter J et al. | β | 2009 | β |
| Genetics of dopamine receptors and drug addiction: a comprehensive review. | Le Foll B et al. | β | 2009 | β |
| Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution. | Doehring A et al. | β | 2009 | β |
| Haplotype diversity and linkage disequilibrium at DRD2 locus--a study on four population groups of Andhra Pradesh, India. | Saraswathy KN et al. | β | 2009 | β |
| Haplotype frequencies at the DRD2 locus in populations of the East European Plain. | Flegontova OV et al. | β | 2009 | β |
| Impact of the dopamine receptor gene family on temperament traits in a population-based birth cohort. | Nyman ES et al. | β | 2009 | β |
| Implications of gene-drug interactions in smoking cessation for improving the prevention of chronic degenerative diseases. | Quaak M et al. | β | 2009 | β |
| Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population. | Sieminska A et al. | β | 2009 | β |
| Interaction between DRD2 C957T polymorphism and an acute psychosocial stressor on reward-related behavioral impulsivity. | White MJ et al. | β | 2009 | β |
| Lack of association of DRD2 rs1800497 (Taq1A) polymorphism with smoking cessation in a nicotine replacement therapy randomized trial. | MunafΓ² MR et al. | β | 2009 | β |
| Neurogenetics of dopaminergic receptor supersensitivity in activation of brain reward circuitry and relapse: proposing "deprivation-amplification relapse therapy" (DART). | Blum K et al. | β | 2009 | β |
| Neurotransmission-related genetic polymorphisms, negative affectivity traits, and gender predict tobacco abstinence symptoms across 44 days with and without nicotine patch. | Gilbert DG et al. | β | 2009 | β |
| New insights into the genetics of addiction. | Li MD et al. | β | 2009 | β |
| Pharmacogenetics of antipsychotic-induced side effects. | Lencz T et al. | β | 2009 | β |
| Polymorphisms in genes modulating the dopamine system: do they inf luence outcome and response to medication after traumatic brain injury? | McAllister TW | β | 2009 | β |
| Prediction of deleterious non-synonymous single nucleotide polymorphisms of genes related to ethanol-induced toxicity. | Wang LL et al. | β | 2009 | β |
| Psychobiological traits in the risk profile for overeating and weight gain. | Davis C | β | 2009 | β |
| Sex heterogeneity in pharmacogenetic smoking cessation clinical trials. | Schnoll RA et al. | β | 2009 | β |
| Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African-American sample. | Huang W et al. | β | 2009 | β |
| The ANKK1 kinase gene and psychiatric disorders. | Ponce G et al. | β | 2009 | β |
| The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans. | Voisey J et al. | β | 2009 | β |
| The impact of genetic research on our understanding of normal cognitive ageing: 1995 to 2009. | Payton A | β | 2009 | β |
| The impact of genetic variation in DRD2 and SLC6A3 on smoking cessation in a cohort of participants 1 year after enrollment in a lung cancer screening study. | Styn MA et al. | β | 2009 | β |
| The interaction of reward genes with environmental factors in contribution to alcoholism in mexican americans. | Du Y et al. | β | 2009 | β |
| Unraveling the molecular mechanisms of alcohol dependence. | Kalsi G et al. | β | 2009 | β |
| A cost-effectiveness analysis of genetic testing of the DRD2 Taq1A polymorphism to aid treatment choice for smoking cessation. | Welton NJ et al. | β | 2008 | β |
| Antipsychotic-induced tardive dyskinesia and polymorphic variations in COMT, DRD2, CYP1A2 and MnSOD genes: a meta-analysis of pharmacogenetic interactions. | Bakker PR et al. | β | 2008 | β |
| Approach to the genetics of alcoholism: a review based on pathophysiology. | KΓΆhnke MD | β | 2008 | β |
| Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety. | Childs E et al. | β | 2008 | β |
| Association of dopamine and opioid receptor genetic polymorphisms with response to methadone maintenance treatment. | Crettol S et al. | β | 2008 | β |
| Behavioral phenotypes of impulsivity related to the ANKK1 gene are independent of an acute stressor. | White MJ et al. | β | 2008 | β |
| Comment on "Genetically determined differences in learning from errors". | Lucht M et al. | β | 2008 | β |
| Dopamine receptor genetic polymorphisms and body composition in undernourished pastoralists: an exploration of nutrition indices among nomadic and recently settled Ariaal men of northern Kenya. | Eisenberg DT et al. | β | 2008 | β |
| Dopaminergic mutations: within-family association and linkage in multiplex alcohol dependence families. | Hill SY et al. | β | 2008 | β |
| DRD2 and ANKK1 genotype in alcohol-dependent patients with psychopathic traits: association and interaction study. | Ponce G et al. | β | 2008 | β |
| Gene polymorphism influencing treatment response in psychotic patients in a naturalistic setting. | Alenius M et al. | β | 2008 | β |
| Genes and cigarette smoking. | MunafΓ² MR et al. | β | 2008 | β |
| Genetic influences on smoking cessation and relapse in pregnant women. | Triche EW et al. | β | 2008 | β |
| Genetics of nicotine dependence and pharmacotherapy. | Lessov-Schlaggar CN et al. | β | 2008 | β |
| Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence. | Laucht M et al. | β | 2008 | β |
| Genetic variation in the dopamine D4 receptor (DRD4) gene and smoking cessation: follow-up of a randomised clinical trial of transdermal nicotine patch. | David SP et al. | β | 2008 | β |
| Genetic variation in the dopamine pathway and smoking cessation. | David SP et al. | β | 2008 | β |
| Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence. | Yang BZ et al. | β | 2008 | β |
| Meta-analysis of the association of the Taq1A polymorphism with the risk of alcohol dependency: a HuGE gene-disease association review. | Smith L et al. | β | 2008 | β |
| Neuroimaging, genetics and the treatment of nicotine addiction. | Ray R et al. | β | 2008 | β |
| Reward sensitivity and the D2 dopamine receptor gene: A case-control study of binge eating disorder. | Davis C et al. | β | 2008 | β |
| Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: a replication and extension study. | McAllister TW et al. | β | 2008 | β |
| Taq1A polymorphism in the dopamine D2 receptor gene as a predictor of clinical response to aripiprazole. | Kwon JS et al. | β | 2008 | β |
| Taq1A polymorphism in the dopamine D2 receptor gene predicts brain metabolic response to aripiprazole in healthy male volunteers. | Kim E et al. | β | 2008 | β |
| The A1 allele of the D2 dopamine receptor gene region, alcohol expectancies and drinking refusal self-efficacy are associated with alcohol dependence severity. | Connor JP et al. | β | 2008 | β |
| The association between DRD2/ANKK1, 5-HTTLPR gene, and specific personality trait on antisocial alcoholism among Han Chinese in Taiwan. | Wu CY et al. | β | 2008 | β |
| Using genetic data in cognitive neuroscience: from growing pains to genuine insights. | Green AE et al. | β | 2008 | β |
| ADHD candidate gene study in a population-based birth cohort: association with DBH and DRD2. | Nyman ES et al. | β | 2007 | β |
| A dopamine D2 receptor gene-related polymorphism is associated with schizophrenia in a Spanish population isolate. | Parsons MJ et al. | β | 2007 | β |
| Alcohol consumption is associated with an interaction between DRD2 exon 8 A/A genotype and self-directedness in males. | Lucht M et al. | β | 2007 | β |
| An association study of DRD2 and COMT polymorphisms with novelty seeking and harm avoidance scores, in two independent samples of depressed patients. | Light KJ et al. | β | 2007 | β |
| Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. | Yang BZ et al. | β | 2007 | β |
| Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias. | MunafΓ² MR et al. | β | 2007 | β |
| Association study of tardive dyskinesia and twelve DRD2 polymorphisms in schizophrenia patients. | Zai CC et al. | β | 2007 | β |
| Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: analysis of pooled data from two clinical trials. | David SP et al. | β | 2007 | β |
| D2 dopamine receptor (DRD2) gene Taq1A polymorphism and the eating-related psychological traits in eating disorders (anorexia nervosa and bulimia) and obesity. | Nisoli E et al. | β | 2007 | β |
| Dopamine genes and pathological gambling in discordant sib-pairs. | da Silva Lobo DS et al. | β | 2007 | β |
| Dopamine receptor genes (DRD2, DRD3 and DRD4) and gene-gene interactions associated with smoking-related behaviors. | Vandenbergh DJ et al. | β | 2007 | β |
| Examining impulsivity as an endophenotype using a behavioral approach: a DRD2 TaqI A and DRD4 48-bp VNTR association study. | Eisenberg DT et al. | β | 2007 | β |
| Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1. | Dick DM et al. | β | 2007 | β |
| Food reinforcement, the dopamine D2 receptor genotype, and energy intake in obese and nonobese humans. | Epstein LH et al. | β | 2007 | β |
| From dopaminergic genes to psychiatric disorders. | Hoenicka J et al. | β | 2007 | β |
| Genetics and smoking cessation improving outcomes in smokers at risk. | Lerman CE et al. | β | 2007 | β |
| Genetic variation and shared biological susceptibility underlying comorbidity in neuropsychiatry. | Palomo T et al. | β | 2007 | β |
| Overview of the pharmacogenomics of cigarette smoking. | Ho MK et al. | β | 2007 | β |
| Pharmacogenetic clinical trial of sustained-release bupropion for smoking cessation. | David SP et al. | β | 2007 | β |
| Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research. | Arranz MJ et al. | β | 2007 | β |
| Pharmacogenetics and smoking cessation with nicotine replacement therapy. | Ray R et al. | β | 2007 | β |
| Pharmacogenetics of antiparkinsonian drug treatment: a systematic review. | Arbouw ME et al. | β | 2007 | β |
| Pharmacogenetics of risperidone response and induced side effects. | Correia C et al. | β | 2007 | β |
| Season of birth and dopamine receptor gene associations with impulsivity, sensation seeking and reproductive behaviors. | Eisenberg DT et al. | β | 2007 | β |
| Test of association between TaqIA A1 allele and alcohol use disorder phenotypes in a sample of adolescent patients with serious substance and behavioral problems. | Sakai JT et al. | β | 2007 | β |
| The DRD2 TaqI-B polymorphism and its relationship to smoking abstinence and withdrawal symptoms. | Robinson JD et al. | β | 2007 | β |
| The relationship between the therapeutic response to risperidone and the dopamine D2 receptor polymorphism in Chinese schizophrenia patients. | Xing Q et al. | β | 2007 | β |
| C957T polymorphism of the dopamine D2 receptor gene modulates the effect of nicotine on working memory performance and cortical processing efficiency. | Jacobsen LK et al. | β | 2006 | β |
| Candidate gene studies in the 21st century: meta-analysis, mediation, moderation. | MunafΓ² MR | β | 2006 | β |
| Can pharmacogenetics help smokers quit? | MunafΓ² M et al. | β | 2006 | β |
| DOPA decarboxylase gene is associated with nicotine dependence. | Zhang H et al. | β | 2006 | β |
| Dopamine D2 receptor gene variants and quantitative measures of positive and negative symptom response following clozapine treatment. | Hwang R et al. | β | 2006 | β |
| DRD2 genetic variation in relation to smoking and obesity in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. | Morton LM et al. | β | 2006 | β |
| Drugs and genotypes: how pharmacogenetic information could improve smoking cessation treatment. | Lee AM et al. | β | 2006 | β |
| Evaluation of a structural polymorphism in the ankyrin repeat and kinase domain containing 1 (ANKK1) gene and the activation of executive attention networks. | Fossella J et al. | β | 2006 | β |
| Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations. | Gelernter J et al. | β | 2006 | β |
| P300 development during adolescence: effects of DRD2 genotype. | Berman SM et al. | β | 2006 | β |
| Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors. | Hurd YL | β | 2006 | β |
| Polymorphisms in the DBH and DRD2 gene regions and smoking behavior. | Freire MT et al. | β | 2006 | β |
| Role of functional genetic variation in the dopamine D2 receptor (DRD2) in response to bupropion and nicotine replacement therapy for tobacco dependence: results of two randomized clinical trials. | Lerman C et al. | β | 2006 | β |
| Symbiotic relationship of pharmacogenetics and drugs of abuse. | Rutter JL | β | 2006 | β |
| The genetics of gambling and behavioral addictions. | Lobo DS et al. | β | 2006 | β |
| Association between the DRD2 gene Taq1A (C32806T) polymorphism and alcohol consumption in social drinkers. | MunafΓ² MR et al. | β | 2005 | β |
| Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations. | Hwang R et al. | β | 2005 | β |
| Dopamine receptor D2 gene polymorphisms are associated in Taiwanese children with Tourette syndrome. | Lee CC et al. | β | 2005 | β |
| Ebrii gignunt ebrios--One drunkard begets another: the genetics of alcohol dependence. | Ball D | β | 2005 | β |
| Effect of the dopamine D2 receptor T allele on response latency after mild traumatic brain injury. | McAllister TW et al. | β | 2005 | β |
| Evolution of the DRD2 gene haplotype and its association with alcoholism in Mexican Americans. | Luo HR et al. | β | 2005 | β |
| Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction. | Kreek MJ et al. | β | 2005 | β |
| Neurogenetic interactions and aberrant behavioral co-morbidity of attention deficit hyperactivity disorder (ADHD): dispelling myths. | Comings DE et al. | β | 2005 | β |
| Pharmacogenetics and nicotine addiction treatment. | MunafΓ² MR et al. | β | 2005 | β |
| The contribution of genetics to addiction therapy approaches. | Edenberg HJ et al. | β | 2005 | β |
| The 5-HT(2A) -1438G/A polymorphism in anorexia nervosa: a combined analysis of 316 trios from six European centres. | Gorwood P et al. | β | 2002 | β |