Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.

paper Cited Public

Authors: Meaney, Michael J; Szyf, Moshe
Year: 2005
Journal: Dialogues in clinical neuroscience
PMID: 16262207
DOI: 10.31887/DCNS.2005.7.2/mmeaney
PMCID: PMC3181727

#	Section	Preview
60	How does maternal care alter cytosine methylation?	replication independent, active demethylation hours after fertilization, well before the initiation…
61	How does maternal care alter cytosine methylation?	Earlier studies from Szyf's122 laboratory extracted active DNA demethylase activity from a human…
62	How does maternal care alter cytosine methylation?	be fully explained. Interestingly, MBD2 increased gene expression in those instances where promoter…
63	How does maternal care alter cytosine methylation?	To test the hypothesis that MBD2 is associated with maternally induced demethylation, we performed…
64	Reversal of the maternal effect on GR expression and HPA responses to stress	These findings suggest that maternal behavior produces an active demethylation process at selected…
65	Reversal of the maternal effect on GR expression and HPA responses to stress	These findings beg the question of how maternal high LG might activate a demethylation of the GR…
66	Reversal of the maternal effect on GR expression and HPA responses to stress	repressor complex that includes methylated DNA binding proteins and HDACs. This hypothesis predicts…
67	Reversal of the maternal effect on GR expression and HPA responses to stress	previously established that pharmacological activation of chromatin structure by HDAC inhibitors can…
68	Reversal of the maternal effect on GR expression and HPA responses to stress	eliminates the effect of maternal care. As expected, enhanced NGFIA binding to the exon 17 promoter…
69	Reversal of the maternal effect on GR expression and HPA responses to stress	These findings have important implications for our understanding of the mechanisms linking early…
70	Dissection of the molecular mechanisms linking maternal behavior and active demethylation of GR exon 17 promoter in the hippocampus	The data discussed above support the hypothesis that histone acetylation could produce active…
71	Dissection of the molecular mechanisms linking maternal behavior and active demethylation of GR exon 17 promoter in the hippocampus	following 4 days of treatment. Treatment of hippocampal cells in culture with 5-HT also results in…
72	Dissection of the molecular mechanisms linking maternal behavior and active demethylation of GR exon 17 promoter in the hippocampus	promoter through an increase in cAMP Since increased cAMP activates NGFIA, it seems that ectopic…
73	Dissection of the molecular mechanisms linking maternal behavior and active demethylation of GR exon 17 promoter in the hippocampus	To test the hypothesis that NGFIA targets demethylation to GR exon 17 promoter we resorted to…
74	Dissection of the molecular mechanisms linking maternal behavior and active demethylation of GR exon 17 promoter in the hippocampus	these manipulations abolished the ability of NGFIA to activate and demethylate the GR exon 17…
75	Experience-dependent chromatin plasticity? Environmental variability meets epigenomic predictability	In summary, our findings suggest that shortly after birth there is a wave of de novo methylation…
76	Experience-dependent chromatin plasticity? Environmental variability meets epigenomic predictability	The defining question of early experience studies concerns the mechanism by which environmental…
77	Experience-dependent chromatin plasticity? Environmental variability meets epigenomic predictability	epigenomic status of the exon 17 GR promoter. The developmental timecourse study is critical. Recall…
78	Experience-dependent chromatin plasticity? Environmental variability meets epigenomic predictability	to clearly define the nature of gene-environment interactions during development and how such…
79	Experience-dependent chromatin plasticity? Environmental variability meets epigenomic predictability	reasonably subtle variations in environmental conditions might serve as a major source of epigenetic…

Name	Type
32P-labelled synthetic oligonucleotide local	drug
3' CpG site local	drug
3' CpG site local	variant
5' CpG dinucleotide local	drug
5' CpG site local	variant
5' CpG site methylation of NFIA consensus sequence in exon 17 NR3C1 promoter local	phenotype
5-CT local	drug
5' cytosine point mutation local	variant
5-HT	drug
5-HT1A receptor	drug
5-HT7 receptor	drug
5-HT7 receptor antagonist local	drug
5-HT signaling local	drug
8-bromo-cAMP local	drug
8-bromocAMP local	drug
acetylated H3 local	drug
Acetylated H3 local	drug
acetylation	drug
ACTH	drug
active chromatin local	drug
Active demethylation local	phenotype
adenosine	drug
adenylyl cyclase	drug
Adult low-LG offspring local	cohort
adult offspring of high-LG mothers local	cohort
adult postmitotic tissues local	cohort
adverse childhood experiences	phenotype
Alternative exon 1 sequences local	variant
Amnion's Horn local	anatomy
amygdala	anatomy
Amygdala-locus ceruleus activity local	phenotype
anterior pituitary	anatomy
Anxiolytic response to acute benzodiazepine administration local	phenotype
basolateral amygdala	anatomy
B cell local	drug
behavioral and neuroendocrine responses to stress local	phenotype
behavioral responses to stress local	phenotype
behavioral response to stress local	phenotype
Behavioral response to stress local	phenotype
Behavioral sensitivity to acute benzodiazepine administration local	phenotype
behavioral stress response local	phenotype
benzodiazepines	drug
BIRC5 local	gene
BrdU	drug
BZ agonists local	drug
cAMP	drug
CBP	gene
central nucleus of amygdala local	anatomy
Central nucleus of amygdala local	anatomy
chromatin	drug
Contact time with pups local	phenotype
cortex	anatomy
corticosterone	drug
corticosterone response magnitude local	phenotype
CpG local	drug
CREB1	gene
CREBBP	gene
CRF	drug
CRF mRNA local	gene
CRF receptor local	gene
CRH	gene
cytosine	drug
Dampened HPA response to stress local	phenotype
day-6 rat pups local	cohort
decreased CRF mRNA expression local	phenotype
decreased CRF receptor levels local	phenotype
decreased hypothalamic CRF mRNA expression local	phenotype
decreased startle response local	phenotype
defensive responses local	phenotype
demethylases local	gene
de novo methylation local	phenotype
dMBD2/3 local	gene
DNA	drug
DNA demethylase local	drug
DNA demethylation local	phenotype
DNA methylation	drug
DNA methylation pattern local	phenotype
DNA methyltransferase	drug
DNMTs	gene
DOI local	drug
Early life events local	phenotype
early maternal behavior local	phenotype
Egr1	gene
endocrine responses to stress local	phenotype
endocrine response to stress local	phenotype
enhanced glucocorticoid negative-feedback sensitivity local	phenotype
environmental conditions local	drug
environmental programming local	phenotype
enzyme	drug
epigenomic changes local	drug
epigenomic modifications local	drug
Epstein-Barr virus	drug
ERBB2 local	gene
Exon 17 GR promoter local	variant
exon 17 NR3C1 promoter methylation local	phenotype
exon 17 promoter local	drug
Extracellular signals local	drug
fearful response to stress local	phenotype
fear under novelty local	phenotype
GABA	phenotype
GABAA/BZ receptor local	gene
GABAA/BZ receptor binding local	phenotype
GABAA receptor subunit expression local	phenotype
Gabra1	gene
GABRA3	gene
Gabra4	gene
Gabrg1	gene
Gabrg2	gene
Gastric cancer	phenotype
gene	gene
gene expression	phenotype
gene function local	phenotype
gene silencing	phenotype
glucocorticoid receptor	gene
glucocorticoids	drug
greater burying of electrified probe local	phenotype
GR exon 17 mRNA variant local	variant
GR exon 17 promoter local	drug
GR exon 17 promoter hypomethylation local	phenotype
GR exon 17 splice variant local	variant
H3 acetylation local	phenotype
H8 local	drug
handling local	drug
handling local	phenotype
HATs	gene
HDAC inhibitors	drug
HDACs	gene
HEK293 local	drug
HEK293 cells	cohort
high-LG local	cohort
high-LG local	phenotype
High-LG local	cohort
High-LG cohort local	cohort
high-LG dams local	phenotype
High-LG group local	cohort
high-LG mothers local	cohort
High-LG mothers local	cohort
High-LG mothers local	phenotype
high-LG offspring local	cohort
High-LG offspring local	cohort
High-LG offspring local	phenotype
Hippocampal GR expression local	phenotype
hippocampal GR mRNA level local	phenotype
hippocampus	anatomy
histone	drug
histone acetylation	drug
histone acetyltransferase local	drug
histone acetyltransferase local	gene
Histone deacetylases local	drug
histone tail local	drug
HK2 local	gene
HOXA5 local	gene
HOXB5	gene
HPA activity	phenotype
HPA responses local	phenotype
HPA responses to stress local	phenotype
HPA response to stress local	phenotype
HPA stress response local	phenotype
Htr7	gene
hypothalamic CRF mRNA expression local	phenotype
hypothalamus	anatomy
IL-2 local	gene
increased exploration in novel environment local	phenotype
increased GABAA/BZ receptor levels local	phenotype
increased GR expression local	phenotype
Increased hippocampal GR expression local	phenotype
increased hippocampal GR mRNA expression local	phenotype
infant mice local	cohort
Intracellular second-messenger systems local	drug
Lactating female rats local	cohort
licking/grooming (LG) local	phenotype
Licking/Grooming (LG) local	phenotype
locus ceruleus	anatomy
low-LG local	cohort
low-LG local	phenotype
Low-LG local	cohort
Low-LG cohort local	cohort
Low-LG group local	cohort
low-LG mothers local	cohort
low-LG mothers local	phenotype
Low-LG mothers local	cohort
Low-LG mothers local	phenotype
low-LG offspring local	cohort
Low-LG offspring local	cohort
Low-LG offspring local	phenotype
luciferase	drug
luciferase reporter local	drug
lung cancer	phenotype
maintenance DNA methyltransferase local	drug
maternal behavior	phenotype
maternal care local	drug
maternal care	phenotype
maternal effects local	phenotype
maternal high LG local	phenotype
maternal LG local	phenotype
Maternal LG local	phenotype
maternal LG frequency local	phenotype
Maternal licking/grooming local	phenotype
Maternal licking/grooming (LG) local	phenotype
MBD2 local	gene
MeCP2	gene
Metastatic breast cancer local	phenotype
methiothepin local	drug
methylated DNA binding protein local	gene
Methylated DNA binding proteins local	drug
methyl cytosines local	drug
mineralocorticoid receptor local	gene
Mineralocorticoid receptor local	gene
Myc	gene
Neonatal handling local	phenotype
Neonatal rats	cohort
neonates	cohort
neuroendocrine response to stress local	phenotype
neurons	phenotype
Newborn offspring of high-LG mothers local	cohort
Newborn offspring of low-LG mothers local	cohort
NFIA	gene
NGFIA response element local	drug
noradrenaline	drug
Nr3c1	gene
NR3C1 exon 17 promoter local	gene
nucleosome	drug
Number of pups to weaning local	phenotype
offspring	cohort
offspring of high-LG mothers local	cohort
offspring of high-LG mothers fostered to low-LG dams local	cohort
offspring of low-LG mothers cross-fostered to high-LG dams local	cohort
ovarian cancer	phenotype
paraformaldehyde	drug
paraventricular nucleus	anatomy
paraventricular nucleus (PVN)	anatomy
parental care local	phenotype
Parental care local	phenotype
parental imprinting local	phenotype
phenotype	phenotype
phosphorylation	drug
Pindolol local	drug
PKA	drug
Plasma corticosterone level local	phenotype
PLAU local	gene
postnatal day-6 pups local	cohort
postnatal handling local	cohort
postnatal handling local	drug
Postnatal handling local	phenotype
prefrontal cortex	anatomy
pup LG frequency local	phenotype
Pup weaning weight local	phenotype
PVN	anatomy
Quipazine local	drug
Rat pup local	cohort
reduced plasma ACTH response local	phenotype
reduced plasma corticosterone response local	phenotype
Repressor complexes local	drug
response element local	drug
ribosylation local	drug
septum local	anatomy
serotonin	drug
shorter latency to eat in novel environment local	phenotype
single cytosine epimutation local	variant
sodium bisulfite	drug
Sp1	gene
stable adult behavior local	phenotype
stress	phenotype
stress-induced illness local	phenotype
stress‑induced increase in noradrenaline local	phenotype
stress-reactive offspring local	phenotype
stress response	phenotype
stress‑responsive brain regions local	anatomy
TFMPP local	drug
transcription factor	drug
transcription factors	drug
Trichostatin A local	drug
TSA local	drug
Valproic acid	drug
weaning weight	phenotype
Y chromosome	drug

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In this knowledge base

Title	Year	PMID
Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning.	2018	29305195
Genetic influences on conduct disorder.	2018	27350097
Beyond genotype: serotonin transporter epigenetic modification predicts human brain function.	2014	25086606
Early experience and the development of stress reactivity and regulation in children.	2010	19481109
Psychobiology and molecular genetics of resilience.	2009	19455174

External

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The Long-Term Effects of Neonatal Inflammatory Pain on Cognitive Function and Stress Hormones Depend on the Heterogeneity of the Adolescent Period of Development in Male and Female Rats.	Butkevich IP et al.	—	2021	→
Three putative DNA methyltransferases of Verticillium dahliae differentially contribute to DNA methylation that is dispensable for growth, development and virulence.	Kramer HM et al.	—	2021	→
Transforming Trauma With Lifestyle Medicine.	Gordon JS et al.	—	2021	→
Troubling Neurobiological Vulnerability: Psychiatric Risk and the Adverse Milieu in Environmental Epigenetics Research.	Filipe AM et al.	—	2021	→
Update on the neurodevelopmental theory of depression: is there any 'unconscious code'?	Gałecka M et al.	—	2021	→
Using Monozygotic Twins to Dissect Common Genes in Posttraumatic Stress Disorder and Migraine.	Bainomugisa CK et al.	—	2021	→
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Atypical lateralization in neurodevelopmental and psychiatric disorders: What is the role of stress?	Berretz G et al.	—	2020	→
Childhood trauma, HPA axis activity and antidepressant response in patients with depression.	Nikkheslat N et al.	—	2020	→
Cortisol and Parenting Predict Pathways to Disinhibited Social Engagement and Social Functioning in Previously Institutionalized Children.	DePasquale CE et al.	—	2020	→
Embryonic Heat Conditioning Induces TET-Dependent Cross-Tolerance to Hypothalamic Inflammation Later in Life.	Rosenberg T et al.	—	2020	→
Epigenetic Mechanisms in Irritable Bowel Syndrome.	Mahurkar-Joshi S et al.	—	2020	→
Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts.	Branje S et al.	—	2020	→
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Maternal separation in rodents: a journey from gut to brain and nutritional perspectives.	Rincel M et al.	—	2020	→
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Pathways to inflammation in adolescence through early adversity, childhood depressive symptoms, and body mass index: A prospective longitudinal study of Chilean infants.	Reid BM et al.	—	2020	→
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Early adversity, child neglect, and stress neurobiology: From observations of impact to empirical evaluations of mechanisms.	Blaisdell KN et al.	—	2019	→
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Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms.	Yehuda R et al.	—	2018	→
Life course programming of stress responses in adolescents and young adults in India: Protocol of the Stress Responses in Adolescence and Vulnerability to Adult Non-communicable disease (SRAVANA) Study.	Krishnaveni GV et al.	—	2018	→
"Motherless Children Have the Hardest Time": Epigenetic Programming and Early Life Environment.	Wright RO	—	2018	→
Neonatal mice exposed to a high-fat diet <i>in utero</i> influence the behaviour of their nursing dam.	Baptissart M et al.	—	2018	→
Parenting practices and overweight status of junior high school students in China: A nationally representative study of 19,487 students from 112 schools.	Tan Z et al.	—	2018	→
Prenatal Maternal Stress from a Natural Disaster Alters Urinary Metabolomic Profiles in Project Ice Storm Participants.	Paxman EJ et al.	—	2018	→
Profiling changes in cortical astroglial cells following chronic stress.	Simard S et al.	—	2018	→
Repeated touch and needle-prick stimulation in the neonatal period increases the baseline mechanical sensitivity and postinjury hypersensitivity of adult spinal sensory neurons.	van den Hoogen NJ et al.	—	2018	→
Research domain criteria and the study of trauma in children: Implications for assessment and treatment research.	Stover CS et al.	—	2018	→
The behavioral genetics of nonhuman primates: Status and prospects.	Rogers J	—	2018	→
The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation.	Bush NR et al.	—	2018	→
The effect of enriched environment across ages: A study of anhedonia and BDNF gene induction.	Dong BE et al.	—	2018	→
Validation and psychometric properties of the Russian version of the Touch Experiences and Attitudes Questionnaire (TEAQ-37 Rus).	Trotter P et al.	—	2018	→
Apolipoprotein E: the resilience gene.	James LM et al.	—	2017	→
Associations between early life experience, chronic HPA axis activity, and adult social rank in rhesus monkeys.	Dettmer AM et al.	—	2017	→
COMT Val158Met and MTHFR C677T moderate risk of schizophrenia in response to childhood adversity.	Debost JC et al.	—	2017	→
Cross-fostering: Elucidating the effects of gene×environment interactions on phenotypic development.	McCarty R	—	2017	→
Deubiquitinating Enzyme OTU5 Contributes to DNA Methylation Patterns and Is Critical for Phosphate Nutrition Signals.	Yen MR et al.	—	2017	→
Developmental and Transmittable Origins of Obesity-Associated Health Disorders.	Oestreich AK et al.	—	2017	→
Early-Life Effects on Adult Physical Activity: Concepts, Relevance, and Experimental Approaches.	Garland T et al.	—	2017	→
Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering.	Vogel Ciernia A et al.	—	2017	→
Early rearing history influences oxytocin receptor epigenetic regulation in rhesus macaques.	Baker M et al.	—	2017	→
Genetic and epigenetic epidemiology of chronic widespread pain.	Kerr JI et al.	—	2017	→
Harm avoidance and childhood adversities in patients with obsessive-compulsive disorder and their unaffected first-degree relatives.	Bey K et al.	—	2017	→
Infantile Amnesia: A Critical Period of Learning to Learn and Remember.	Alberini CM et al.	—	2017	→
Juvenile social isolation affects maternal care in rats: involvement of allopregnanolone.	Pisu MG et al.	—	2017	→
Maternal sensitivity and adrenocortical functioning across infancy and toddlerhood: Physiological adaptation to context?	Berry D et al.	—	2017	→
Methylation of the glucocorticoid receptor gene, nuclear receptor subfamily 3, group C, member 1 (NR3C1), in maltreated and nonmaltreated children: Associations with behavioral undercontrol, emotional lability/negativity, and externalizing and internalizing symptoms.	Cicchetti D et al.	—	2017	→
Methylation of the oxytocin receptor gene mediates the effect of adversity on negative schemas and depression.	Simons RL et al.	—	2017	→
Neurobiological and Systemic Effects of Chronic Stress.	McEwen BS	—	2017	→
Parental depression and parent and child stress physiology: Moderation by parental hostility.	Merwin SM et al.	—	2017	→
Paternal personality and social status influence offspring activity in zebrafish.	Zajitschek S et al.	—	2017	→
Pharmacogenetics and Pharmacotherapy of Military Personnel Suffering from Post-traumatic Stress Disorder.	Naß J et al.	—	2017	→
Preclinical and Clinical Evidence of DNA Methylation Changes in Response to Trauma and Chronic Stress.	Matosin N et al.	—	2017	→
PTSD, alcohol dependence, and conduct problems: Distinct pathways via lability and disinhibition.	Simons JS et al.	—	2017	→
The impact of stress at different life stages on physical health and the buffering effects of maternal sensitivity.	Farrell AK et al.	—	2017	→
Threat vigilance and socioeconomic disparities in metabolic health.	Hostinar CE et al.	—	2017	→
Weaponized sex: defensive pseudo-erotic aggression in the service of safety.	Kluft RP	—	2017	→
ALS and FTD: an epigenetic perspective.	Belzil VV et al.	—	2016	→
An epigenomics approach to individual differences and its translation to neuropsychiatric conditions.	Sweatt JD et al.	—	2016	→
Biobehavioral Factors in Child Health Outcomes: The Roles of Maternal Stress, Maternal-Child Engagement, Salivary Cortisol, and Salivary Testosterone.	Clowtis LM et al.	—	2016	→
Breaking the Intergenerational Cycle of Disadvantage: The Three Generation Approach.	Cheng TL et al.	—	2016	→
Childhood adversities and psychosis: evidence, challenges, implications.	Morgan C et al.	—	2016	→
Differential DNA methylation in peripheral blood mononuclear cells in adolescents exposed to significant early but not later childhood adversity.	Esposito EA et al.	—	2016	→
DNA methylation in peripheral tissue of schizophrenia and bipolar disorder: a systematic review.	Teroganova N et al.	—	2016	→
Dynamic DNA methylation controls glutamate receptor trafficking and synaptic scaling.	Sweatt JD	—	2016	→
Early adversity, hypocortisolism, and behavior problems at school entry: A study of internationally adopted children.	Koss KJ et al.	—	2016	→
Early origins of mental disorder - risk factors in the perinatal and infant period.	Newman L et al.	—	2016	→
Epigenetic Patterns Modulate the Connection Between Developmental Dynamics of Parenting and Offspring Psychosocial Adjustment.	Naumova OY et al.	—	2016	→
Epigenetic regulation of the DRD4 gene and dimensions of attention-deficit/hyperactivity disorder in children.	Dadds MR et al.	—	2016	→
Epigenetics: ambiguities and implications.	Stotz K et al.	—	2016	→
Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection.	Sharma G et al.	—	2016	→
In search of the HPA axis activity in unipolar depression patients with childhood trauma: Combined cortisol awakening response and dexamethasone suppression test.	Lu S et al.	—	2016	→
Living long and ageing well: is epigenomics the missing link between nature and nurture?	Rea IM et al.	—	2016	→
Maternal depression across the first years of life compromises child psychosocial adjustment; relations to child HPA-axis functioning.	Apter-Levi Y et al.	—	2016	→
Neonatal maternal separation stress elicits lasting DNA methylation changes in the hippocampus of stress-reactive Wistar Kyoto rats.	McCoy CR et al.	—	2016	→
Oxytocin Pathway Genes: Evolutionary Ancient System Impacting on Human Affiliation, Sociality, and Psychopathology.	Feldman R et al.	—	2016	→
Patterns of anterior versus posterior white matter fractional anistotropy concordance in adult nonhuman primates: Effects of early life stress.	Coplan JD et al.	—	2016	→
Protective effects of chronic mild stress during adolescence in the low-novelty responder rat.	Rana S et al.	—	2016	→
Resource base influences genome-wide DNA methylation levels in wild baboons (Papio cynocephalus).	Lea AJ et al.	—	2016	→
Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex.	McEwen BS et al.	—	2016	→
[Stress-induced hyperalgesia (SIH) as a consequence of emotional deprivation and psychosocial traumatization in childhood : Implications for the treatment of chronic pain].	Egle UT et al.	—	2016	→
Studying longitudinal trajectories in animal models of psychiatric illness and their translation to the human condition.	Driscoll CA et al.	—	2016	→
Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014.	Aas M et al.	—	2016	→
The Links Between Stress and Depression: Psychoneuroendocrinological, Genetic, and Environmental Interactions.	Tafet GE et al.	—	2016	→
The neurobiological basis of human aggression: A review on genetic and epigenetic mechanisms.	Waltes R et al.	—	2016	→
The Neurobiology of Intervention and Prevention in Early Adversity.	Fisher PA et al.	—	2016	→
The neurobiology of mammalian parenting and the biosocial context of human caregiving.	Feldman R	—	2016	→
Associations between early life stress and gene methylation in children.	Romens SE et al.	—	2015	→
Behavioral stress reduces RIP140 expression in astrocyte and increases brain lipid accumulation.	Feng X et al.	—	2015	→
Childhood and later life stressors and increased inflammatory gene expression at older ages.	Levine ME et al.	—	2015	→
Early-life risperidone administration alters maternal-offspring interactions and juvenile play fighting.	Gannon MA et al.	—	2015	→
Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition.	Moloney RD et al.	—	2015	→
Early Life Stress, Nicotinic Acetylcholine Receptors and Alcohol Use Disorders.	Holgate JY et al.	—	2015	→
Early life trauma, depression and the glucocorticoid receptor gene--an epigenetic perspective.	Smart C et al.	—	2015	→
Effects of prenatal and postnatal depression, and maternal stroking, at the glucocorticoid receptor gene.	Murgatroyd C et al.	—	2015	→
Examining the joint contribution of placental NR3C1 and HSD11B2 methylation for infant neurobehavior.	Appleton AA et al.	—	2015	→
Genes and life-style factors in BELFAST nonagenarians: Nature, Nurture and Narrative.	Rea JN et al.	—	2015	→
GLUCOCORTICOIDS AND LEARNING DURING INFANCY.	Gunnar MR	—	2015	→
Individual Differences in Childhood Behavior Disorders Associated With Epigenetic Modulation of the Cortisol Receptor Gene.	Dadds MR et al.	—	2015	→
Inflammation and neuronal plasticity: a link between childhood trauma and depression pathogenesis.	Cattaneo A et al.	—	2015	→
Invited address: "The times they are a-changin'" gene expression, neuroplasticity, and developmental research.	Simons RL et al.	—	2015	→
Maternal antenatal anxiety, postnatal stroking and emotional problems in children: outcomes predicted from pre- and postnatal programming hypotheses.	Sharp H et al.	—	2015	→
Maternal prenatal depressive symptoms predict infant NR3C1 1F and BDNF IV DNA methylation.	Braithwaite EC et al.	—	2015	→
Mechanisms of stress in the brain.	McEwen BS et al.	—	2015	→
Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility.	Nasca C et al.	—	2015	→
Mothers' and Fathers' Sensitivity and Children's Cognitive Development in Low-Income, Rural Families.	Mills-Koonce WR et al.	—	2015	→
Parental buffering of fear and stress neurobiology: Reviewing parallels across rodent, monkey, and human models.	Gunnar MR et al.	—	2015	→
Prenatal stress and its effects on the fetus and the child: possible underlying biological mechanisms.	Glover V	—	2015	→
Psychometric Properties of the Parent-Infant Caregiving Touch Scale.	Koukounari A et al.	—	2015	→
Recognizing Resilience: Learning from the Effects of Stress on the Brain.	McEwen BS et al.	—	2015	→
Regulation of TRH neurons and energy homeostasis-related signals under stress.	Joseph-Bravo P et al.	—	2015	→
Relationship of clinical course of illness variables to medical comorbidities in 900 adult outpatients with bipolar disorder.	Post RM et al.	—	2015	→
Summary cortisol reactivity indicators: Interrelations and meaning.	Khoury JE et al.	—	2015	→
Synaptic rewiring of stress-sensitive neurons by early-life experience: a mechanism for resilience?	Singh-Taylor A et al.	—	2015	→
The Cortisol Paradox of Trauma-Related Disorders: Lower Phasic Responses but Higher Tonic Levels of Cortisol Are Associated with Sexual Abuse in Childhood.	Schalinski I et al.	—	2015	→
The neuroendocrinology of social isolation.	Cacioppo JT et al.	—	2015	→
The Regulation of Task Performance: A Trans-Disciplinary Review.	Clark I et al.	—	2015	→
The Vindication of Lamarck? Epigenetics at the Intersection of Law and Mental Health.	DeLisi M et al.	—	2015	→
Addiction science: Uncovering neurobiological complexity.	Volkow ND et al.	—	2014	→
Allomaternal nursing in humans.	Hewlett BS et al.	—	2014	→
A review on the evidence of transgenerational transmission of posttraumatic stress disorder vulnerability.	Yahyavi ST et al.	—	2014	→
Author's reply: To PMID 24991682.	Hewlett BS et al.	—	2014	→
Beyond genotype: serotonin transporter epigenetic modification predicts human brain function.	Nikolova YS et al.	—	2014	→
Childhood adversities and adolescent depression: a matter of both risk and resilience.	Oldehinkel AJ et al.	—	2014	→
Discriminative and affective touch: sensing and feeling.	McGlone F et al.	—	2014	→
DNA memories of early social life.	Hoffmann A et al.	—	2014	→
DNA methylation biomarkers: cancer and beyond.	Mikeska T et al.	—	2014	→
DNA methylation of pituitary growth hormone is involved in male growth superiority of Nile tilapia (Oreochromis niloticus).	Zhong H et al.	—	2014	→
Early life trauma and attachment: immediate and enduring effects on neurobehavioral and stress axis development.	Rincón-Cortés M et al.	—	2014	→
Effects of negative stressors on DNA methylation in the brain: implications for mood and anxiety disorders.	Hing B et al.	—	2014	→
Effects of short-term exposure to inhalable particulate matter on DNA methylation of tandem repeats.	Guo L et al.	—	2014	→
Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders.	Zhu L et al.	—	2014	→
Epigenome: biosensor of cumulative exposure to chemical and nonchemical stressors related to environmental justice.	Olden K et al.	—	2014	→
Exploring the complexity of intellectual disability in fetal alcohol spectrum disorders.	Chokroborty-Hoque A et al.	—	2014	→
Extended evolutionary psychology: the importance of transgenerational developmental plasticity.	Stotz K	—	2014	→
Fine-scale population epigenetic structure in relation to gastrointestinal parasite load in red grouse (Lagopus lagopus scotica).	Wenzel MA et al.	—	2014	→
Food for love: the role of food offering in empathic emotion regulation.	Hamburg ME et al.	—	2014	→
Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?	Stilling RM et al.	—	2014	→
G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter.	Stevens AJ et al.	—	2014	→
Isolation during the prepubertal period associated with chronic access to palatable diets: effects on plasma lipid profile and liver oxidative stress.	Arcego DM et al.	—	2014	→
Long-term effects of gestational nicotine exposure and food-restriction on gene expression in the striatum of adolescent rats.	Ilott NE et al.	—	2014	→
Maternal exposure to low levels of corticosterone during lactation protects against experimental inflammatory colitis-induced damage in adult rat offspring.	Petrella C et al.	—	2014	→
Methylation of the oxytocin receptor gene and oxytocin blood levels in the development of psychopathy.	Dadds MR et al.	—	2014	→
Post-traumatic stress disorder--a diagnostic and therapeutic challenge.	Frommberger U et al.	—	2014	→
Psychobiological mechanisms underlying the social buffering of the hypothalamic-pituitary-adrenocortical axis: a review of animal models and human studies across development.	Hostinar CE et al.	—	2014	→
Social deprivation and the HPA axis in early development.	Koss KJ et al.	—	2014	→
The ABC of moral development: an attachment approach to moral judgment.	Govrin A	—	2014	→
The "domestication syndrome" in mammals: a unified explanation based on neural crest cell behavior and genetics.	Wilkins AS et al.	—	2014	→
The effects of SES on infant and maternal diurnal salivary cortisol output.	Clearfield MW et al.	—	2014	→
The importance of glia in dealing with stress.	Woodbury-Fariña MA	—	2014	→
The intergenerational effects of early adversity.	Galler J et al.	—	2014	→
The multifaceted mineralocorticoid receptor.	Gomez-Sanchez E et al.	—	2014	→
The potential biomarker panels for identification of Major Depressive Disorder (MDD) patients with and without early life stress (ELS) by metabonomic analysis.	Ding X et al.	—	2014	→
Transgenerational effects of social stress on social behavior, corticosterone, oxytocin, and prolactin in rats.	Babb JA et al.	—	2014	→
Being suckled in a large litter mitigates the effects of early-life stress on hypothalamic-pituitary-adrenal axis function in the male rat.	Clarke M et al.	—	2013	→
Calcium-based dendritic excitability and its regulation in the deep cerebellar nuclei.	Schneider ER et al.	—	2013	→
Cortisol and depression: three questions for psychiatry.	Herbert J	—	2013	→
Cortisol response and desire to binge following psychological stress: comparison between obese subjects with and without binge eating disorder.	Rosenberg N et al.	—	2013	→
DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP.	Powell TR et al.	—	2013	→
Effects of early life social stress on endocrinology, maternal behavior, and lactation in rats.	Carini LM et al.	—	2013	→
Enriched early life experiences reduce adult anxiety-like behavior in rats: a role for insulin-like growth factor 1.	Baldini S et al.	—	2013	→
Epigenetic mechanisms in learned fear: implications for PTSD.	Zovkic IB et al.	—	2013	→
Epigenetic mechanisms of depression and antidepressant action.	Vialou V et al.	—	2013	→
Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence.	Essex MJ et al.	—	2013	→
Exploration of the Hypothalamic-Pituitary-Adrenal Axis to Improve Animal Welfare by Means of Genetic Selection: Lessons from the South African Merino.	Hough D et al.	—	2013	→
Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins.	Ouellet-Morin I et al.	—	2013	→
Intimate partner violence exposure in early childhood: an ecobiodevelopmental perspective.	Herman-Smith R	—	2013	→
Introduction to special issue on the neurobiology of depression.	Barch DM	—	2013	→
Litter size, age-related memory impairments, and microglial changes in rat dentate gyrus: stereological analysis and three dimensional morphometry.	Viana LC et al.	—	2013	→
Maternal behavior as an early modulator of neurobehavioral offspring responses by Sprague-Dawley rats.	Sequeira-Cordero A et al.	—	2013	→
Maternal stimulation in infancy predicts hypothalamic-pituitary-adrenal axis reactivity in young men.	Schmid B et al.	—	2013	→
Patterning in placental 11-B hydroxysteroid dehydrogenase methylation according to prenatal socioeconomic adversity.	Appleton AA et al.	—	2013	→
Perinatal programming of neuroendocrine mechanisms connecting feeding behavior and stress.	Spencer SJ	—	2013	→
Potential translational targets revealed by linking mouse grooming behavioral phenotypes to gene expression using public databases.	Roth A et al.	—	2013	→
Prospectively assessed early life experiences in relation to cortisol reactivity in adolescents at risk for asthma.	Kelsay K et al.	—	2013	→
Quality of maternal and paternal care predicts later stress reactivity in the cooperatively-breeding marmoset (Callithrix geoffroyi).	Birnie AK et al.	—	2013	→
Reflections on the interaction of psychogenic stress systems in humans: the stress coherence/compensation model.	Andrews J et al.	—	2013	→
Research review: the role of cytokines in depression in adolescents: a systematic review.	Mills NT et al.	—	2013	→
Resilience in mental health: linking psychological and neurobiological perspectives.	Rutten BP et al.	—	2013	→
Role of childhood adversity in the development of medical co-morbidities associated with bipolar disorder.	Post RM et al.	—	2013	→
Social environmental effects on gene regulation.	Tung J et al.	—	2013	→
Stability of parental care across siblings from undisturbed and challenged pregnancies: intrinsic maternal dispositions of female rhesus monkeys.	Shirtcliff EA et al.	—	2013	→
The ADHD debate: being mindful of complexity and wary of reductionist explanations and polarization: Commentary on 'A social relational critique of the biomedical definition and treatment of ADHD; ethical, practical and political implications'	Thapar A et al.	—	2013	→
The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course.	McEwen BS et al.	—	2013	→
The Developmental Effects of Early Life Stress: An Overview of Current Theoretical Frameworks.	Hostinar CE et al.	—	2013	→
The role of nutraceuticals in the management of autism.	Alanazi AS	—	2013	→
The social brain: neurobiological basis of affiliative behaviours and psychological well-being.	Walker SC et al.	—	2013	→
The social defeat hypothesis of schizophrenia: an update.	Selten JP et al.	—	2013	→
Adoption as an intervention for institutionally reared children: HPA functioning and developmental status.	Kroupina MG et al.	—	2012	→
Basal anxiety-like behavior predicts differences in dendritic morphology in the medial prefrontal cortex in two strains of rats.	Miller MM et al.	—	2012	→
Biological indicators of illness risk in offspring of bipolar parents: targeting the hypothalamic-pituitary-adrenal axis and immune system.	Duffy A et al.	—	2012	→
Brain on stress: how the social environment gets under the skin.	McEwen BS	—	2012	→
Child development in the context of adversity: experiential canalization of brain and behavior.	Blair C et al.	—	2012	→
Childhood stressful events, HPA axis and anxiety disorders.	Faravelli C et al.	—	2012	→
DNA methylation patterns in cord blood DNA and body size in childhood.	Relton CL et al.	—	2012	→
DNA methylation program during development.	Zhou FC	—	2012	→
Enhanced stress responses in adolescent versus adult rats exposed to cues of predation threat, and peer interaction as a predictor of adult defensiveness.	Wright LD et al.	—	2012	→
Epigenetic and genetic factors predict women's salivary cortisol following a threat to the social self.	Edelman S et al.	—	2012	→
Expression profiles of mitochondrial genes in the frontal cortex and the caudate nucleus of developing humans and mice selectively bred for high and low fear.	Choi KH et al.	—	2012	→
Frequency of infant stroking reported by mothers moderates the effect of prenatal depression on infant behavioural and physiological outcomes.	Sharp H et al.	—	2012	→
Genetic and environmental vulnerabilities in children with neurodevelopmental disorders.	Karmiloff-Smith A et al.	—	2012	→
Genetic contributions to intergroup responses: a cautionary perspective.	Ratner KG et al.	—	2012	→
Have studies of the developmental regulation of behavioral phenotypes revealed the mechanisms of gene-environment interactions?	Hall FS et al.	—	2012	→
Individual development and evolution: experiential canalization of self-regulation.	Blair C et al.	—	2012	→
Neurobiology of resilience.	Russo SJ et al.	—	2012	→
[Overview of acute and chronic stress responses].	Moisan MP et al.	—	2012	→
Prenatal lipopolysaccharide exposure increases anxiety-like behaviors and enhances stress-induced corticosterone responses in adult rats.	Lin YL et al.	—	2012	→
Social influences on neuroplasticity: stress and interventions to promote well-being.	Davidson RJ et al.	—	2012	→
Stress and anxiety: structural plasticity and epigenetic regulation as a consequence of stress.	McEwen BS et al.	—	2012	→
Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4.	Sailaja BS et al.	—	2012	→
The Confluence of Adverse Early Experience and Puberty on the Cortisol Awakening Response.	Quevedo K et al.	—	2012	→
The lifelong effects of early childhood adversity and toxic stress.	Shonkoff JP et al.	—	2012	→
The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder.	Wu K et al.	—	2012	→
The Role of Parenting in the Emergence of Human Emotion: New Approaches to the Old Nature-Nurture Debate.	Pollak SD	—	2012	→
Addiction as a systems failure: focus on adolescence and smoking.	Baler RD et al.	—	2011	→
A life course approach to the development of mental skills.	Richards M et al.	—	2011	→
Animal models of human anxiety disorders: reappraisal from a developmental psychopathology vantage point.	Lampis V et al.	—	2011	→
Association between income and the hippocampus.	Hanson JL et al.	—	2011	→
A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development.	Juster RP et al.	—	2011	→
Blunted cortisol responses to stress signal social and behavioral problems among maltreated/bullied 12-year-old children.	Ouellet-Morin I et al.	—	2011	→
Childhood adversity, trauma and abuse: context and consequences.	Boyce P et al.	—	2011	→
Chronic stress, cognitive functioning and mental health.	Marin MF et al.	—	2011	→
Dark matters in AMD genetics: epigenetics and stochasticity.	Hjelmeland LM	—	2011	→
Developmental programming of the metabolic syndrome - critical windows for intervention.	Vickers MH	—	2011	→
Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences.	Claessens SE et al.	—	2011	→
Differences in mouse maternal care behavior - is there a genetic impact of the glucocorticoid receptor?	Chourbaji S et al.	—	2011	→
Early adversity and adult health outcomes.	Taylor SE et al.	—	2011	→
Early rearing interacts with temperament and housing to influence the risk for motor stereotypy in rhesus monkeys (Macaca mulatta).	Vandeleest JJ et al.	—	2011	→
Effects of neonatal treatment with valproic acid on vasopressin immunoreactivity and olfactory behaviour in mice.	Murray EK et al.	—	2011	→
Endophenotypes and the diagnosis of personality disorders.	Paris J	—	2011	→
Environment-sensitive epigenetics and the heritability of complex diseases.	Furrow RE et al.	—	2011	→
Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated northern Swedish population.	Ceulemans S et al.	—	2011	→
Fostering in mice induces cardiovascular and metabolic dysfunction in adulthood.	Matthews PA et al.	—	2011	→
Growth delay as an index of allostatic load in young children: predictions to disinhibited social approach and diurnal cortisol activity.	Johnson AE et al.	—	2011	→
Hyperhomocysteinemia does not affect global DNA methylation and nicotinamide N-methyltransferase expression in mice.	Bromberg A et al.	—	2011	→
Infant neurobehavioral development.	Lester BM et al.	—	2011	→
Juvenile offspring of rats exposed to restraint stress in late gestation have impaired cognitive performance and dysregulated progestogen formation.	Paris JJ et al.	—	2011	→
Maternal obesity and developmental programming of metabolic disorders in offspring: evidence from animal models.	Li M et al.	—	2011	→
Mechanical-tactile stimulation (MTS) intervention in a neonatal stress model improves long-term outcomes on bone.	Haley S et al.	—	2011	→
Neonatal programming of innate immune function.	Spencer SJ et al.	—	2011	→
Normalizing the development of cortisol regulation in maltreated infants through preventive interventions.	Cicchetti D et al.	—	2011	→
Postnatal blockade of androgen receptors or aromatase impair the expression of stress hypothalamic-pituitary-adrenal axis habituation in adult male rats.	Bingham B et al.	—	2011	→
Post-traumatic stress disorder: the neurobiological impact of psychological trauma.	Sherin JE et al.	—	2011	→
Quality of early mother-child interaction associated with depressive psychopathology in the offspring: a prospective study from infancy to adulthood.	Schmid B et al.	—	2011	→
Rat pup social motivation: a critical component of early psychological development.	Cromwell HC	—	2011	→
Salivary cortisol mediates effects of poverty and parenting on executive functions in early childhood.	Blair C et al.	—	2011	→
Stressed and depressed? Check your GDNF for epigenetic repression.	Miller CA	—	2011	→
Stress-induced depressive behaviors are correlated with Par-4 and DRD2 expression in rat striatum.	Zhu X et al.	—	2011	→
Stress, vulnerability and resilience, a developmental approach.	Broekman BF	—	2011	→
The contribution of maternal stress to preterm birth: issues and considerations.	Wadhwa PD et al.	—	2011	→
Using animal models to disentangle the role of genetic, epigenetic, and environmental influences on behavioral outcomes associated with maternal anxiety and depression.	Tarantino LM et al.	—	2011	→
Variations in maternal care alter corticosterone and 17beta-estradiol levels, estrous cycle and folliculogenesis and stimulate the expression of estrogen receptors alpha and beta in the ovaries of UCh rats.	Amorim JP et al.	—	2011	→
Challenges to bonnet monkey (Macaca radiata) social groups: Mother-infant dyad and infant social interactions.	Laudenslager ML et al.	—	2010	→
Childhood separation experience predicts HPA axis hormonal responses in late adulthood: a natural experiment of World War II.	Pesonen AK et al.	—	2010	→
Childhood traumata, Dexamethasone Suppression Test and psychiatric symptoms: a trans-diagnostic approach.	Faravelli C et al.	—	2010	→
Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking.	Kim HS et al.	—	2010	→
Early experience and the development of stress reactivity and regulation in children.	Loman MM et al.	—	2010	→
Epigenetic effects of shiftwork on blood DNA methylation.	Bollati V et al.	—	2010	→
Epigenetic regulation of the expression of genes involved in steroid hormone biosynthesis and action.	Martinez-Arguelles DB et al.	—	2010	→
Evidence for a familial correlation between increased reactivity to stress and positive psychotic symptoms.	Lataster T et al.	—	2010	→
Family life on the prairie.	Bales KL	—	2010	→
Fear conditioning and early life vulnerabilities: two distinct pathways of emotional dysregulation and brain dysfunction in PTSD.	Lanius RA et al.	—	2010	→
Genetics as a tool for the dissociation of mental operations over the course of development.	Fossella JA et al.	—	2010	→
Genetics of human social behavior.	Ebstein RP et al.	—	2010	→
Investigations of HPA function and the enduring consequences of stressors in adolescence in animal models.	McCormick CM et al.	—	2010	→
Maternal touch and feed as critical regulators of behavioral and stress responses in the offspring.	Walker CD	—	2010	→
Mechanisms linking early life stress to adult health outcomes.	Taylor SE	—	2010	→
Plasticity of the stress response early in life: mechanisms and significance.	Korosi A et al.	—	2010	→
Resilience under conditions of extreme stress: a multilevel perspective.	Cicchetti D	—	2010	→
Social influences on health: is serotonin a critical mediator?	Way BM et al.	—	2010	→
Stress and the Development of Self-Regulation in Context.	Blair C	—	2010	→
Systems theory and cascades in developmental psychopathology.	Cox MJ et al.	—	2010	→
The differential impacts of early physical and sexual abuse and internalizing problems on daytime cortisol rhythm in school-aged children.	Cicchetti D et al.	—	2010	→
The genetics of mood disorders.	Lau JY et al.	—	2010	→
Adverse rearing experiences enhance responding to both aversive and rewarding stimuli in juvenile rhesus monkeys.	Nelson EE et al.	—	2009	→
A review of candidate pathways underlying the association between asthma and major depressive disorder.	Van Lieshout RJ et al.	—	2009	→
Assessing the molecular genetics of the development of executive attention in children: focus on genetic pathways related to the anterior cingulate cortex and dopamine.	Brocki K et al.	—	2009	→
Cardiovascular health of Finnish war evacuees 60 years later.	Alastalo H et al.	—	2009	→
[Childhood maltreatment and adult psychopathology: pathways to hypothalamic-pituitary-adrenal axis dysfunction].	Mello MF et al.	—	2009	→
Chromatin ultrastructural abnormalities in leukocytes, as peripheral markers of bipolar patients.	Chrysanthou-Piterou M et al.	—	2009	→
Cultural neuroscience and psychopathology: prospects for cultural psychiatry.	Choudhury S et al.	—	2009	→
Desperately driven and no brakes: developmental stress exposure and subsequent risk for substance abuse.	Andersen SL et al.	—	2009	→
Developmental origins of health and disease: environmental exposures.	Swanson JM et al.	—	2009	→
Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene.	Heim C et al.	—	2009	→
Genetics of emotion regulation.	Canli T et al.	—	2009	→
Global leukocyte DNA methylation is not altered in euthymic bipolar patients.	Bromberg A et al.	—	2009	→
Glucocorticoid receptor polymorphisms in major depression.	Claes S	—	2009	→
Health psychology: developing biologically plausible models linking the social world and physical health.	Miller G et al.	—	2009	→
Identifying atypical cortisol patterns in young children: The benefits of group-based trajectory modeling.	Van Ryzin MJ et al.	—	2009	→
Imaging phenotypes of major depressive disorder: genetic correlates.	Savitz JB et al.	—	2009	→
Length of time between onset of childhood sexual abuse and emergence of depression in a young adult sample: a retrospective clinical report.	Teicher MH et al.	—	2009	→
Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling.	Miller GE et al.	—	2009	→
Massage accelerates brain development and the maturation of visual function.	Guzzetta A et al.	—	2009	→
Paediatric major depressive disorder: neurobiology and implications for early intervention.	Cullen K et al.	—	2009	→
Pathways from science findings to health benefits.	Rutter M et al.	—	2009	→
Postnatal programming of the innate immune response.	Galic MA et al.	—	2009	→
Poverty-alleviation program participation and salivary cortisol in very low-income children.	Fernald LC et al.	—	2009	→
Psychiatry and neuroscience.	Paris J	—	2009	→
Psychobiology and molecular genetics of resilience.	Feder A et al.	—	2009	→
Sex differences in histone modifications in the neonatal mouse brain.	Tsai HW et al.	—	2009	→
Stress, the hippocampus, and epilepsy.	Joëls M	—	2009	→
The neurobiological toll of child abuse and neglect.	Neigh GN et al.	—	2009	→
The relevance of epigenetics to PTSD: implications for the DSM-V.	Yehuda R et al.	—	2009	→
The role played by the interaction between genetic factors and attachment in the stress response in infancy.	Frigerio A et al.	—	2009	→
Addiction and the brain antireward system.	Koob GF et al.	—	2008	→
ADHD, lead exposure and prevention: how much lead or how much evidence is needed?	Nigg JT	—	2008	→
Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: a prospective study on the fetal origins of depressed mood.	Van den Bergh BR et al.	—	2008	→
Biological implications of gene-environment interaction.	Rutter M	—	2008	→
Bipolar disorder and suicide: research synthesis and clinical translation.	McIntyre RS et al.	—	2008	→
Continued exposure to maternal distress in early life is associated with an increased risk of childhood asthma.	Kozyrskyj AL et al.	—	2008	→
Developmental Neuroscience Perspectives on Emotion Regulation.	Goldsmith HH et al.	—	2008	→
Diet and the epigenetic (re)programming of phenotypic differences in behavior.	McGowan PO et al.	—	2008	→
Early care experiences and HPA axis regulation in children: a mechanism for later trauma vulnerability.	Gunnar MR et al.	—	2008	→
Early deprivation and home basal cortisol levels: a study of internationally adopted children.	Kertes DA et al.	—	2008	→
Effects of maternal strain on ethanol responses in reciprocal F1 C57BL/6J and DBA/2J hybrid mice.	Gabriel KI et al.	—	2008	→
Enhanced cutaneous hypersensitivity reactions are associated with ovine high and low cortisol responsiveness to acute endotoxin challenge.	You Q et al.	—	2008	→
Epigenetic principles and mechanisms underlying nervous system functions in health and disease.	Mehler MF	—	2008	→
Epigenetic programming of the stress response in male and female rats by prenatal restraint stress.	Darnaudéry M et al.	—	2008	→
Epigenetics and its implications for behavioral neuroendocrinology.	Crews D	—	2008	→
Experiential and genetic contributions to depressive- and anxiety-like disorders: clinical and experimental studies.	Anisman H et al.	—	2008	→
Fetal programming of hypothalamic-pituitary-adrenal (HPA) axis function and behavior by synthetic glucocorticoids.	Kapoor A et al.	—	2008	→
Gene-environment interactions in schizophrenia: review of epidemiological findings and future directions.	van Os J et al.	—	2008	→
Gene environment interplay: nonhuman primate models in the study of resilience and vulnerability.	Bennett AJ	—	2008	→
HPA axis and sleep: identifying subtypes of major depression.	Antonijevic I	—	2008	→
Increased depressive behaviour in females and heightened corticosterone release in males to swim stress after adolescent social stress in rats.	Mathews IZ et al.	—	2008	→
Interdisciplinarity and systems science to improve population health: a view from the NIH Office of Behavioral and Social Sciences Research.	Mabry PL et al.	—	2008	→
Intervention effects on foster parent stress: associations with child cortisol levels.	Fisher PA et al.	—	2008	→
Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring.	Novikova SI et al.	—	2008	→
Molecular genetics of the stress-responsive adrenocortical axis.	Redei EE	—	2008	→
Naturally occurring variations in maternal care modulate the effects of repeated neonatal pain on behavioral sensitivity to thermal pain in the adult offspring.	Walker CD et al.	—	2008	→
Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions.	Chapman CR et al.	—	2008	→
Prenatal stress and risk for autism.	Kinney DK et al.	—	2008	→
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain.	McGowan PO et al.	—	2008	→
Social bonds and posttraumatic stress disorder.	Charuvastra A et al.	—	2008	→
Stress-induced changes in corticosteroid receptor expression in primate hippocampus and prefrontal cortex.	Patel PD et al.	—	2008	→
The link between childhood trauma and depression: insights from HPA axis studies in humans.	Heim C et al.	—	2008	→
Variation in the ovine cortisol response to systemic bacterial endotoxin challenge is predominantly determined by signalling within the hypothalamic-pituitary-adrenal axis.	You Q et al.	—	2008	→
Augmented hypothalamic corticotrophin-releasing hormone mRNA and corticosterone responses to stress in adult rats exposed to perinatal hypoxia.	Raff H et al.	—	2007	→
Developmental programming through epigenetic changes.	Nuyt AM et al.	—	2007	→
Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects.	Thapar A et al.	—	2007	→
Effects of a therapeutic intervention for foster preschoolers on diurnal cortisol activity.	Fisher PA et al.	—	2007	→
Influence of genetics on disease susceptibility and progression.	Duff GW	—	2007	→
Long-term behavioral consequences of brief, repeated neonatal isolation.	Knuth ED et al.	—	2007	→
Maternal care, the epigenome and phenotypic differences in behavior.	Szyf M et al.	—	2007	→
Maternal separation enhances neuronal activation and cardiovascular responses to acute stress in borderline hypertensive rats.	Sanders BJ et al.	—	2007	→
Psychological stressors as a model of maternal adversity: diurnal modulation of corticosterone responses and changes in maternal behavior.	Léonhardt M et al.	—	2007	→
Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha gene.	Huo L et al.	—	2007	→
Stress inoculation-induced indications of resilience in monkeys.	Lyons DM et al.	—	2007	→
Stressor-specific regulation of distinct brain-derived neurotrophic factor transcripts and cyclic AMP response element-binding protein expression in the postnatal and adult rat hippocampus.	Nair A et al.	—	2007	→
The dynamic epigenome and its implications in toxicology.	Szyf M	—	2007	→
The molecular neurobiology of depression.	Shelton RC	—	2007	→
The neurobiology of stress and development.	Gunnar M et al.	—	2007	→
Toward a psychobiologic understanding of youth health disparities.	Susman EJ	—	2007	→
Bringing basic research on early experience and stress neurobiology to bear on preventive interventions for neglected and maltreated children.	Gunnar MR et al.	—	2006	→
Cross-talk between nuclear receptors and nuclear factor kappaB.	De Bosscher K et al.	—	2006	→
Developmental plasticity of HPA and fear responses in rats: a critical review of the maternal mediation hypothesis.	Macrì S et al.	—	2006	→
Early deprivation, but not maternal separation, attenuates rise in corticosterone levels after exposure to a novel environment in both juvenile and adult female rats.	Rees SL et al.	—	2006	→
Effects of therapeutic interventions for foster children on behavioral problems, caregiver attachment, and stress regulatory neural systems.	Fisher PA et al.	—	2006	→
Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation.	D'Alessio AC et al.	—	2006	→
Evolutionary theory, psychiatry, and psychopharmacology.	Stein DJ	—	2006	→
Keeping up NF-kappaB appearances: epigenetic control of immunity or inflammation-triggered epigenetics.	Vanden Berghe W et al.	—	2006	→