Marital quality moderates genetic and environmental influences on the internalizing spectrum.
paper
Cited
Public
- Authors
- South, Susan C; Krueger, Robert F
- Year
- 2008
- Journal
- Journal of abnormal psychology
- PMID
- 19025229
- DOI
- 10.1037/a0013499
- PMCID
- PMC2602959
Poor marital quality is a reliable correlate of internalizing problems, but the etiology of this association has yet to be examined. Marital distress may exert its influence by acting as a stressor that enables the expression of latent genetic risk for internalizing psychopathology. The authors examined this question using 379 twin pairs, assessed for marital quality, symptoms of major depression (MD), generalized anxiety disorder (GAD), panic attacks (PA), and neuroticism (N). A phenotypic factor analysis confirmed that one factor best accounted for the variance shared between MD, GAD, PA, and N. After accounting for genetic influences on the general Internalizing factor, there were residual genetic influences on N but no specific genetic influences on any other individual internalizing syndrome. The authors found overlap between the genetic influences on marital quality and the internalizing spectrum. Finally, biometrical moderation models revealed that genetic effects on the Internalizing factor increased as the marital quality deteriorated (marital quality high: h(2) = 0.05; marital quality low: h(2) = 0.29), suggesting that those with a genetic predisposition to internalizing syndromes may be more likely to express this predisposition in the context of a dissatisfying marriage.
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| Name | Type |
|---|---|
| aggression | phenotype |
| agoraphobia | phenotype |
| American adults | cohort |
| anhedonia | phenotype |
| anxiety | phenotype |
| Change in weight local | phenotype |
| CIDI-SF local | drug |
| conflict-laden marriage local | phenotype |
| depression | phenotype |
| depressive symptoms | phenotype |
| Distress- and Worry-Prone Personality local | phenotype |
| Dizygotic female twin pairs local | cohort |
| Dizygotic male twin pairs local | cohort |
| dysthymia | phenotype |
| expressed emotion local | phenotype |
| externalizing behavior | phenotype |
| family environment | phenotype |
| fear | phenotype |
| Feeling anxious local | phenotype |
| Feeling down local | phenotype |
| Feeling tense local | phenotype |
| Feeling tired local | phenotype |
| Feeling worried local | phenotype |
| female Australian twin pairs local | cohort |
| Five Factor model | phenotype |
| Five-Factor Model | phenotype |
| generalized anxiety disorder | phenotype |
| household tasks disagreement local | phenotype |
| hyperarousal | phenotype |
| internalizing disorders | phenotype |
| Internalizing factor | phenotype |
| Internalizing factor score local | phenotype |
| Internalizing Spectrum Disorders local | phenotype |
| internalizing syndromes local | phenotype |
| Internalizing syndromes local | phenotype |
| leisure time activities disagreement local | phenotype |
| MacArthur Foundation Survey of Midlife Development in the United States local | cohort |
| major depressive disorder | phenotype |
| marital distress local | phenotype |
| marital satisfaction | phenotype |
| marital status | phenotype |
| MIDUS local | cohort |
| MIDUS main (non-twin) sample local | cohort |
| MIDUS study local | cohort |
| MIDUS survey local | cohort |
| MIDUS twin sample local | cohort |
| money disagreement local | phenotype |
| Monozygotic female twin pairs local | cohort |
| Monozygotic male twin pairs local | cohort |
| mood disorders | phenotype |
| National Longitudinal Survey of Labor Market Experiences local | cohort |
| National Survey of Families and Households local | cohort |
| negative affect | phenotype |
| neuroticism | phenotype |
| neurotic personality style local | phenotype |
| optimism local | phenotype |
| Optimism local | phenotype |
| panic disorder | phenotype |
| pathology | phenotype |
| Personality composite of optimism and aggression local | phenotype |
| personality traits | phenotype |
| physical health | phenotype |
| poor response to treatment local | phenotype |
| positive affect | phenotype |
| Post-Traumatic Stress Disorder | phenotype |
| psychiatric disorders | phenotype |
| psychiatric relapse local | phenotype |
| psychological distress | phenotype |
| psychopathology | phenotype |
| relationship quality | phenotype |
| separation or divorce risk local | phenotype |
| social phobia | phenotype |
| social responsibilities local | phenotype |
| specific phobia | phenotype |
| subjective well-being | phenotype |
| Swedish population | cohort |
| Thoughts about death local | phenotype |
| Trouble concentrating local | phenotype |
| Trouble with sleep local | phenotype |
| Twin cohort | cohort |
| Virginia Twin Registry | cohort |
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