apoptosis phenotype

Aliases

OPC death, apoptosis, cell death, natural apoptosis, oligodendrocyte death

Related entities (34)

Mentioned in (387)

Papers in which this entity is mentioned.

• DrBioRight 2.0: an LLM-powered bioinformatics chatbot for large-scale cancer functional proteomics analysis. (2025)
• Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. (2025)
• Functional analysis of cancer-associated germline risk variants. (2025)
• Alcohol Exposure May Increase Prenatal Choline Needs Through Redirection of Choline into Lipid Synthesis Rather than Methyl Donation. (2025)
• Mutations in the bone morphogenetic protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations. (2025)
• Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. (2024)
• Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells. (2024)
• ENPP1 Immunobiology as a Therapeutic Target. (2023)
• The ameliorative effects of choline on ethanol-induced cell death in the neural tube of susceptible BXD strains of mice. (2023)
• Embryonic ethanol exposure disrupts craniofacial neuromuscular integration in zebrafish larvae. (2023)
• Impact of alcohol exposure on neural development and network formation in human cortical organoids. (2023)
• Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. (2023)
• Gene-alcohol interactions in birth defects. (2023)
• Deterministic evolution and stringent selection during preneoplasia. (2023)
• Alcohol and Immunology: Mechanisms of multi-organ damage. Summary of the 2022 alcohol and Immunology research interest group (AIRIG) meeting. (2023)
• High-throughput detection of craniofacial defects in fluorescent zebrafish. (2023)
• Towards understandings of serine/arginine-rich splicing factors. (2023)
• RNA splicing dysregulation and the hallmarks of cancer. (2023)
• Chronic oligodendrocyte injury in central nervous system pathologies. (2022)
• Prenatal alcohol exposure contributes to negative pregnancy outcomes by altering fetal vascular dynamics and the placental transcriptome. (2022)
• At the dawn: cell-free DNA fragmentomics and gene regulation. (2022)
• Epigenetics in Alzheimer's Disease. (2022)
• Explainable multiview framework for dissecting spatial relationships from highly multiplexed data. (2022)
• Untargeted Metabolome Analysis Reveals Reductions in Maternal Hepatic Glucose and Amino Acid Content That Correlate with Fetal Organ Weights in a Mouse Model of Fetal Alcohol Spectrum Disorders. (2022)
• The pro-apoptotic Bax gene modifies susceptibility to craniofacial dysmorphology following gastrulation-stage alcohol exposure. (2022)
• Rodent models in placental research. Implications for fetal origins of adult disease. (2022)
• Beneficial Effects of Betaine: A Comprehensive Review. (2021)
• Micro-RNA-125a mediates the effects of hypomethylating agents in chronic myelomonocytic leukemia. (2021)
• Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. (2021)
• Loss of tumor protein 53 protects against alcohol-induced facial malformations in mice and zebrafish. (2021)
• Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions. (2021)
• Neurotoxic reactive astrocytes induce cell death via saturated lipids. (2021)
• Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
• Infant circulating MicroRNAs as biomarkers of effect in fetal alcohol spectrum disorders. (2021)
• Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway. (2021)
• Macrophage Polarization States in the Tumor Microenvironment. (2021)
• Prenatal alcohol exposure disrupts Sonic hedgehog pathway and primary cilia genes in the mouse neural tube. (2021)
• Simultaneous single cell measurements of intranuclear proteins and gene expression (2021)
• Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease. (2021)
• Evaluating Neurodevelopmental Consequences of Perinatal Exposure to Antiretroviral Drugs: Current Challenges and New Approaches. (2021)
• Gestational age and birth growth parameters as early predictors of fetal alcohol spectrum disorders. (2021)
• Current Socioeconomic Status Correlates With Brain Volumes in Healthy Children and Adolescents but Not in Children With Prenatal Alcohol Exposure. (2020)
• Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex. (2020)
• Tead transcription factors differentially regulate cortical development. (2020)
• Emerging Roles of SRSF3 as a Therapeutic Target for Cancer. (2020)
• ABHD4-dependent developmental anoikis safeguards the embryonic brain. (2020)
• Choline, Neurological Development and Brain Function: A Systematic Review Focusing on the First 1000 Days. (2020)
• Transcriptome-Wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure. (2020)
• Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
• Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma. (2020)
• Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction. (2019)
• Super-enhancers: critical roles and therapeutic targets in hematologic malignancies. (2019)
• Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish. (2019)
• Alcohol Use in Pregnancy. (2019)
• Effects of nicotine exposure on murine mandibular development. (2019)
• Prenatal nicotine exposure induces depression‑like behavior in adolescent female rats via modulating neurosteroid in the hippocampus. (2019)
• Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes. (2019)
• Maternal circulating miRNAs that predict infant FASD outcomes influence placental maturation. (2019)
• Designing combination therapies with modeling chaperoned machine learning. (2019)
• Ethanol activates immune response in lymphoblastoid cells. (2019)
• Genome-Informed Targeted Therapy for Osteosarcoma. (2019)
• The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data. (2019)
• Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. (2018)
• Circular DNA elements of chromosomal origin are common in healthy human somatic tissue. (2018)
• The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer. (2018)
• Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning. (2018)
• Quantification of subclonal selection in cancer from bulk sequencing data. (2018)
• Enhanced detection of circulating tumor DNA by fragment size analysis. (2018)
• Sex and gender differences in developmental programming of metabolism. (2018)
• Sex Differences in Early Postnatal Microglial Colonization of the Developing Rat Hippocampus Following a Single-Day Alcohol Exposure. (2018)
• Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain. (2018)
• Interactive effects of prenatal alcohol exposure and chronic stress in adulthood on anxiety-like behavior and central stress-related receptor mRNA expression: Sex- and time-dependent effects. (2018)
• PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
• Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. (2018)
• Neural correlates of verbal memory in youth with heavy prenatal alcohol exposure. (2018)
• Immune Dysfunction and Autoimmunity as Pathological Mechanisms in Autism Spectrum Disorders. (2018)
• Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypes in a Zebrafish Model of 22q11.2 Deletion Syndrome. (2018)
• EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma. (2018)
• Altered structural brain changes and neurocognitive performance in pediatric HIV. (2017)
• Neurotrophins in the Brain: Interaction With Alcohol Exposure During Development. (2017)
• Demystifying the cytokine network: Mathematical models point the way. (2017)
• Universal Patterns of Selection in Cancer and Somatic Tissues. (2017)
• Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1. (2017)
• ChimeRScope: a novel alignment-free algorithm for fusion transcript prediction using paired-end RNA-Seq data. (2017)
• Maternal choline supplementation during murine pregnancy modulates placental markers of inflammation, apoptosis and vascularization in a fetal sex-dependent manner. (2017)
• Patient-derived xenografts undergo mouse-specific tumor evolution. (2017)
• Larger Subcortical Gray Matter Structures and Smaller Corpora Callosa at Age 5 Years in HIV Infected Children on Early ART. (2017)
• Postnatal choline supplementation selectively attenuates hippocampal microRNA alterations associated with developmental alcohol exposure. (2017)
• Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. (2017)
• Environmental factors influencing the risk of autism. (2017)
• Sexual Dimorphism of miRNAs Secreted by Bovine -produced Embryos. (2017)
• Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling. (2017)
• The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network. (2017)
• Epigenetics studies of fetal alcohol spectrum disorder: where are we now? (2017)
• Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. (2017)
• Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis. (2017)
• PGBD5 promotes site-specific oncogenic mutations in human tumors. (2017)
• Dietary choline levels modify the effects of prenatal alcohol exposure in rats. (2017)
• Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis. (2016)
• Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders. (2016)
• Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin. (2016)
• Gray matter maturation and cognition in children with different APOE ε genotypes. (2016)
• Inhibition of Mammary Cancer Progression in Fetal Alcohol Exposed Rats by β-Endorphin Neurons. (2016)
• Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage. (2016)
• Prenatal Exposure to Arsenic Impairs Behavioral Flexibility and Cortical Structure in Mice. (2016)
• Fragment Length of Circulating Tumor DNA. (2016)
• Developmental ethanol exposure-induced sleep fragmentation predicts adult cognitive impairment. (2016)
• Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure. (2016)
• The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming. (2016)
• Pdgfra and Pdgfrb genetically interact during craniofacial development. (2016)
• Acute alcohol exposure during neurulation: Behavioral and brain structural consequences in adolescent C57BL/6J mice. (2016)
• Oxidative stress signaling to chromatin in health and disease. (2016)
• Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. (2016)
• Evolutionary Insights into RNA trans-Splicing in Vertebrates. (2016)
• The Genetics of Fetal Alcohol Spectrum Disorders. (2016)
• Direct Transcriptional Effects of Apolipoprotein E. (2016)
• Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016)
• Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. (2016)
• Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution. (2016)
• Maternal iron deficiency worsens the associative learning deficits and hippocampal and cerebellar losses in a rat model of fetal alcohol spectrum disorders. (2015)
• Fetal Alcohol Spectrum Disorders: An Overview from the Glia Perspective. (2015)
• The cell cycle regulator CCDC6 is a key target of RNA-binding protein EWS. (2015)
• Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. (2015)
• Mechanisms of retinoic acid signalling and its roles in organ and limb development. (2015)
• Genetic absence of nNOS worsens fetal alcohol effects in mice. II: microencephaly and neuronal losses. (2015)
• Zebrafish retinal defects induced by ethanol exposure are rescued by retinoic acid and folic acid supplement. (2015)
• Effects of all three trimester moderate binge alcohol exposure on the foetal hippocampal formation and olfactory bulb. (2015)
• BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells. (2015)
• Impact of prenatal environmental stress on cortical development. (2015)
• Importance of genetics in fetal alcohol effects: null mutation of the nNOS gene worsens alcohol-induced cerebellar neuronal losses and behavioral deficits. (2015)
• Prenatal alcohol exposure alters steady-state and activated gene expression in the adult rat brain. (2015)
• Low and moderate prenatal ethanol exposures of mice during gastrulation or neurulation delays neurobehavioral development. (2015)
• Selective reduction of cerebral cortex GABA neurons in a late gestation model of fetal alcohol spectrum disorder. (2015)
• MiR-125b protects against ethanol-induced apoptosis in neural crest cells and mouse embryos by targeting Bak 1 and PUMA. (2015)
• Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish. (2015)
• Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. (2015)
• Gonadectomy before puberty increases the number of neurons and glia in the medial prefrontal cortex of female, but not male, rats. (2015)
• A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation. (2014)
• Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation. (2014)
• Modulation of pilocarpine-induced seizures by cannabinoid receptor 1. (2014)
• MicroRNA-29b regulates ethanol-induced neuronal apoptosis in the developing cerebellum through SP1/RAX/PKR cascade. (2014)
• Gene expression in the addicted brain. (2014)
• RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing. (2014)
• A screen of zebrafish mutants identifies ethanol-sensitive genetic loci. (2014)
• MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. (2014)
• Pre-administration of G9a/GLP inhibitor during synaptogenesis prevents postnatal ethanol-induced LTP deficits and neurobehavioral abnormalities in adult mice. (2014)
• CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. (2014)
• Estimating telomere length from whole genome sequence data. (2014)
• Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. (2014)
• Neurodevelopmental benefits of antiretroviral therapy in Ugandan children aged 0-6 years with HIV. (2014)
• Policy: NIH to balance sex in cell and animal studies. (2014)
• Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. (2014)
• Gene expression signatures affected by alcohol-induced DNA methylomic deregulation in human embryonic stem cells. (2014)
• High-throughput transcriptome sequencing identifies candidate genetic modifiers of vulnerability to fetal alcohol spectrum disorders. (2014)
• Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. (2014)
• An evolutionarily conserved mechanism of calcium-dependent neurotoxicity in a zebrafish model of fetal alcohol spectrum disorders. (2014)
• Low-dose maternal alcohol consumption: effects in the hearts of offspring in early life and adulthood. (2014)
• Effects of Acute Prenatal Exposure to Ethanol on microRNA Expression are Ameliorated by Social Enrichment. (2014)
• Genomic factors that shape craniofacial outcome and neural crest vulnerability in FASD. (2014)
• The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
• Neural crest development in fetal alcohol syndrome. (2014)
• Gene-ethanol interactions underlying fetal alcohol spectrum disorders. (2014)
• Genetic influences on brain developmental trajectories on neuroimaging studies: from infancy to young adulthood. (2014)
• Molecular pathways underpinning ethanol-induced neurodegeneration. (2014)
• Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). (2014)
• Clonal evolution in hematological malignancies and therapeutic implications. (2014)
• The impact of environmental factors in severe psychiatric disorders. (2014)
• Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
• EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014)
• MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells. (2014)
• The role of NADPH oxidase in a mouse model of fetal alcohol syndrome. (2014)
• Direct functional consequences of ZRS enhancer mutation combine with secondary long range SHH signalling effects to cause preaxial polydactyly. (2014)
• Effects of one- and three-day binge alcohol exposure in neonatal C57BL/6 mice on spatial learning and memory in adolescence and adulthood. (2014)
• Alcohol modulates expression of DNA methyltranferases and methyl CpG-/CpG domain-binding proteins in murine embryonic fibroblasts. (2013)
• Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure. (2013)
• Ethanol alters gene expression and cell organization during optic vesicle evagination. (2013)
• Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. (2013)
• White matter microstructure abnormalities and executive function in adolescents with prenatal cocaine exposure. (2013)
• Prioritizing Potentially Druggable Mutations with dGene: An Annotation Tool for Cancer Genome Sequencing Data. (2013)
• Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure. (2013)
• Modeling transformations of neurodevelopmental sequences across mammalian species. (2013)
• Ewing sarcoma protein: a key player in human cancer. (2013)
• Cyclic adenosine monophosphate and brain-derived neurotrophic factor decreased oxidative stress and apoptosis in developing hypothalamic neuronal cells: role of microglia. (2013)
• Recent binge drinking predicts smaller cerebellar volumes in adolescents. (2013)
• Alcohol metabolism and epigenetics changes. (2013)
• G9a-mediated histone methylation regulates ethanol-induced neurodegeneration in the neonatal mouse brain. (2013)
• In utero alcohol exposure, epigenetic changes, and their consequences. (2013)
• Alcohol exposure in utero increases susceptibility to prostate tumorigenesis in rat offspring. (2013)
• Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. (2013)
• Vitamin D nutrition in pregnancy: current opinion. (2013)
• Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (2013)
• Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD. (2013)
• Effects of alcohol on the endocrine system. (2013)
• Cholecalciferol attenuates perseverative behavior associated with developmental alcohol exposure in rats in a dose-dependent manner. (2013)
• Prenatal ethanol exposure delays the onset of spermatogenesis in the rat. (2013)
• The role of nutrition in children's neurocognitive development, from pregnancy through childhood. (2013)
• Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders. (2013)
• Intrinsic properties of larval zebrafish neurons in ethanol. (2013)
• Commonality in Down and fetal alcohol syndromes. (2013)
• Interactive effects of dehydroepiandrosterone and testosterone on cortical thickness during early brain development. (2013)
• RNA splicing: a new player in the DNA damage response. (2013)
• Hand in glove: brain and skull in development and dysmorphogenesis. (2013)
• Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brain. (2013)
• Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. (2013)
• The ubiquitin-proteasome system as a critical regulator of synaptic plasticity and long-term memory formation. (2013)
• Different patterns of regional Purkinje cell loss in the cerebellar vermis as a function of the timing of prenatal ethanol exposure in an ovine model. (2013)
• Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice. (2013)
• Neuroprotective actions of perinatal choline nutrition. (2013)
• Reduced expression of brain cannabinoid receptor 1 (Cnr1) is coupled with an increased complementary micro-RNA (miR-26b) in a mouse model of fetal alcohol spectrum disorders. (2013)
• Zebrafish models of human liver development and disease. (2013)
• Effects of Ethanol Exposure during Distinct Periods of Brain Development on Hippocampal Synaptic Plasticity. (2013)
• LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. (2013)
• Over-expression of Nrf2 diminishes ethanol-induced oxidative stress and apoptosis in neural crest cells by inducing an antioxidant response. (2013)
• Nitric oxide rescues thalidomide mediated teratogenicity. (2012)
• 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. (2012)
• Distinct spatiotemporal roles of hedgehog signalling during chick and mouse cranial base and axial skeleton development. (2012)
• Adequacy of maternal iron status protects against behavioral, neuroanatomical, and growth deficits in fetal alcohol spectrum disorders. (2012)
• SOX2 hypomorphism disrupts development of the prechordal floor and optic cup. (2012)
• Opposing actions of ethanol and nicotine on microRNAs are mediated by nicotinic acetylcholine receptors in fetal cerebral cortical-derived neural progenitor cells. (2012)
• Early exposure to alcohol leads to permanent impairment of dendritic excitability in neocortical pyramidal neurons. (2012)
• Housing in environmental complexity following wheel running augments survival of newly generated hippocampal neurons in a rat model of binge alcohol exposure during the third trimester equivalent. (2012)
• Enhanced deficits in long-term potentiation in the adult dentate gyrus with 2nd trimester ethanol consumption. (2012)
• Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. (2012)
• Inflammaging: disturbed interplay between autophagy and inflammasomes. (2012)
• Persistent dose-dependent changes in brain structure in young adults with low-to-moderate alcohol exposure in utero. (2012)
• Sex matters during adolescence: testosterone-related cortical thickness maturation differs between boys and girls. (2012)
• Pubertal testosterone organizes regional volume and neuronal number within the medial amygdala of adult male Syrian hamsters. (2012)
• Effects of prenatal exposure to sodium arsenite on motor and food-motivated behaviors from birth to adulthood in C57BL6/J mice. (2012)
• Molecular genetics of B-precursor acute lymphoblastic leukemia. (2012)
• Corpus callosum alterations in very preterm infants: perinatal correlates and 2 year neurodevelopmental outcomes. (2012)
• The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. (2012)
• Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects. (2012)
• Analysis of sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors. (2012)
• Ethanol-induced face-brain dysmorphology patterns are correlative and exposure-stage dependent. (2012)
• Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice. (2012)
• Ethanol exposure during pregnancy persistently attenuates cranially directed blood flow in the developing fetus: evidence from ultrasound imaging in a murine second trimester equivalent model. (2012)
• Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders. (2012)
• Vitamin D supplementation protects against bone loss associated with chronic alcohol administration in female mice. (2012)
• Prenatal exposure to cigarette smoke or alcohol and cerebellum volume in attention-deficit/hyperactivity disorder and typical development. (2012)
• Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response. (2012)
• Postnatal day 7 ethanol treatment causes persistent reductions in adult mouse brain volume and cortical neurons with sex specific effects on neurogenesis. (2012)
• Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. (2012)
• Gene expression changes in C57BL/6J and DBA/2J mice following prenatal alcohol exposure. (2012)
• The Pediatric Cancer Genome Project. (2012)
• Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons. (2012)
• Massive genomic rearrangement acquired in a single catastrophic event during cancer development. (2011)
• A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories. (2011)
• Teratogenic effects of thalidomide: molecular mechanisms. (2011)
• Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. (2011)
• Fetal alcohol spectrum disorders: experimental treatments and strategies for intervention. (2011)
• Early childhood exposure to anesthesia and risk of developmental and behavioral disorders in a sibling birth cohort. (2011)
• Fetal alcohol spectrum disorders: research challenges and opportunities. (2011)
• Ethanol-induced microphthalmia is not mediated by changes in retinoic acid or sonic hedgehog signaling during retinal neurogenesis. (2011)
• A Drosophila model for fetal alcohol syndrome disorders: role for the insulin pathway. (2011)
• Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease. (2011)
• What choline metabolism can tell us about the underlying mechanisms of fetal alcohol spectrum disorders. (2011)
• Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood. (2011)
• Developmental trajectories during adolescence in males and females: a cross-species understanding of underlying brain changes. (2011)
• Functional connectivity MRI in infants: exploration of the functional organization of the developing brain. (2011)
• Functional consequences of developmentally regulated alternative splicing. (2011)
• The role of DYRK1A in neurodegenerative diseases. (2011)
• The effects of a single memantine treatment on behavioral alterations associated with binge alcohol exposure in neonatal rats. (2011)
• Strain differences in developmental vulnerability to alcohol exposure via embryo culture in mice. (2011)
• Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. (2011)
• Mechanisms that underlie co-variation of the brain and face. (2011)
• Apolipoprotein E: from lipid transport to neurobiology. (2011)
• An integrated ChIP-seq analysis platform with customizable workflows. (2011)
• CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. (2011)
• MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. (2011)
• Tissue plasminogen activator is required for the development of fetal alcohol syndrome in mice. (2011)
• Imaging the impact of prenatal alcohol exposure on the structure of the developing human brain. (2011)
• Effects of early postnatal exposure to ethanol on retinal ganglion cell morphology and numbers of neurons in the dorsolateral geniculate in mice. (2011)
• Molecular mechanisms of long noncoding RNAs. (2011)
• S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors. (2011)
• Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions. (2011)
• Calcium-mediated repression of β-catenin and its transcriptional signaling mediates neural crest cell death in an avian model of fetal alcohol syndrome. (2011)
• Local and regional network function in behaviorally relevant cortical circuits of adult mice following postnatal alcohol exposure. (2011)
• Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome. (2010)
• The role of zinc in the modulation of neuronal proliferation and apoptosis. (2010)
• Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
• Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. (2010)
• Alcohol-induced facial dysmorphology in C57BL/6 mouse models of fetal alcohol spectrum disorder. (2010)
• Reduction of ethanol-induced ocular abnormalities in mice through dietary administration of N-acetylcysteine. (2010)
• Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. (2010)
• Normal development of brain circuits. (2010)
• Linking functional decline of telomeres, mitochondria and stem cells during ageing. (2010)
• Craniofacial birth defects: The role of neural crest cells in the etiology and pathogenesis of Treacher Collins syndrome and the potential for prevention. (2010)
• Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. (2010)
• MicroRNAs: master regulators of ethanol abuse and toxicity? (2010)
• Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. (2010)
• Fetal alcohol exposure increases mammary tumor susceptibility and alters tumor phenotype in rats. (2010)
• Genetic and epigenetic insights into fetal alcohol spectrum disorders. (2010)
• Fetal alcohol spectrum disorders: from research to policy. (2010)
• Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells. (2010)
• The development of gyrification in childhood and adolescence. (2010)
• The basics of brain development. (2010)
• Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. (2010)
• The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos. (2010)
• Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. (2010)
• Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development. (2010)
• Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. (2010)
• MR diffusion tensor imaging: a window into white matter integrity of the working brain. (2010)
• Structural, metabolic, and functional brain abnormalities as a result of prenatal exposure to drugs of abuse: evidence from neuroimaging. (2010)
• Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
• Role of microglia in ethanol's apoptotic action on hypothalamic neuronal cells in primary cultures. (2010)
• Magnetic resonance microscopy-based analyses of the brains of normal and ethanol-exposed fetal mice. (2010)
• Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model. (2010)
• The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example. (2010)
• Prenatal exposure to drugs: effects on brain development and implications for policy and education. (2009)
• Vulnerability of macaque cranial nerve neurons to ethanol is time- and site-dependent. (2009)
• Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. (2009)
• Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. (2009)
• The epigenetics of sex differences in the brain. (2009)
• Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation. (2009)
• The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles. (2009)
• Sexual dimorphism in the white matter of rodents. (2009)
• Alterations in phosphorylated cyclic adenosine monophosphate response element of binding protein activity: a pathway for fetal alcohol syndrome-related neurotoxicity. (2009)
• Choline: an essential nutrient for public health. (2009)
• Fetal effects of psychoactive drugs. (2009)
• Insulin-like growth factor-I mitigates motor coordination deficits associated with neonatal alcohol exposure in rats. (2009)
• Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. (2009)
• Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
• Neurotoxic effects and biomarkers of lead exposure: a review. (2009)
• Neuroimaging of children following prenatal drug exposure. (2009)
• DNA methylation and methyl-CpG binding proteins: developmental requirements and function. (2009)
• An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. (2009)
• Phenotype of apoptotic lymphocytes in children with Down syndrome. (2009)
• Animal models of fetal alcohol spectrum disorders: impact of the social environment. (2009)
• Neuroimaging of children following prenatal drug exposure. (2009)
• Evolution of the neocortex: a perspective from developmental biology. (2009)
• Effects of ethanol and ipsapirone on the expression of genes encoding anti-apoptotic proteins and an antioxidant enzyme in ethanol-treated neurons. (2009)
• Activity-dependent neuroprotective protein-derived peptide, NAP, preventing alcohol-induced apoptosis in fetal brain of C57BL/6 mouse. (2009)
• Mechanisms of neurodegeneration and regeneration in alcoholism. (2009)
• Characterization of white matter microstructure in fetal alcohol spectrum disorders. (2009)
• Ethanol's molecular targets. (2008)
• An alcohol binding site on the neural cell adhesion molecule L1. (2008)
• Modeling the impact of alcohol on cortical development in a dish: strategies from mapping neural stem cell fate. (2008)
• Ethanol consumption during early pregnancy alters the disposition of tangentially migrating GABAergic interneurons in the fetal cortex. (2008)
• Oxidative stress during diabetic pregnancy disrupts cardiac neural crest migration and causes outflow tract defects. (2008)
• Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons. (2008)
• Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling. (2008)
• Nrf2-mediated transcriptional induction of antioxidant response in mouse embryos exposed to ethanol in vivo: implications for the prevention of fetal alcohol spectrum disorders. (2008)
• 3' end mRNA processing: molecular mechanisms and implications for health and disease. (2008)
• Adolescent development of neuron structure in dentate gyrus granule cells of male Syrian hamsters. (2008)
• Mechanism of alcohol-induced oxidative stress and neuronal injury. (2008)
• MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. (2008)
• The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum. (2008)
• Perinatal choline deficiency produces abnormal sensory inhibition in Sprague-Dawley rats. (2008)
• Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. (2007)
• Mechanisms for persistent microphthalmia following ethanol exposure during retinal neurogenesis in zebrafish embryos. (2007)
• Perlecan controls neurogenesis in the developing telencephalon. (2007)
• Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde. (2007)
• PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. (2007)
• L1 cell adhesion molecule is neuroprotective of alcohol induced cell death. (2007)
• Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion. (2006)
• Choline: critical role during fetal development and dietary requirements in adults. (2006)
• Perinatal choline influences brain structure and function. (2006)
• Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brain. (2006)
• Effects of ethanol on photoreceptors and visual function in developing zebrafish. (2006)
• Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis. (2005)
• Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
• Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. (2005)
• Macrophage-derived tumor necrosis factor alpha, an early developmental signal for motoneuron death. (2004)
• Dynamic mapping of human cortical development during childhood through early adulthood. (2004)
• Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. (2004)
• Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes. (2004)
• Structural abnormalities in the brains of human subjects who use methamphetamine. (2004)
• Alcohol and the developing brain: neuroanatomical studies. (2003)
• Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions. (2003)
• Relationship between availability of NMDA receptor subunits and their expression at the synapse. (2002)
• Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. (2002)
• Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure. (2002)
• Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death. (2002)
• Nicotinic receptors mediate changes in spinal motoneuron development and axonal pathfinding in embryonic zebrafish exposed to nicotine. (2002)
• Myelination is altered in insulin-like growth factor-I null mutant mice. (2002)
• Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner. (2001)
• Mechanisms of alcohol-induced damage to the developing nervous system. (2001)
• Modeling alcohol's effects on organs in animal models. (2000)
• Role of founder cell deficit and delayed neuronogenesis in microencephaly of the trisomy 16 mouse. (2000)
• Specific regional transcription of apolipoprotein E in human brain neurons. (1999)
• Alcohol-induced cell death in the embryo. (1997)
• Gestational exposure to ethanol suppresses msx2 expression in developing mouse embryos. (1997)
• Impairments of brain and behavior: the neurological effects of alcohol. (1997)
• Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. (1995)
• Axons of early generated neurons in cingulate cortex pioneer the corpus callosum. (1994)
• Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. (1993)
• Transient IGF-I gene expression during the maturation of functionally related central projection neurons. (1991)

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