Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression.

paper Cited Public

Authors: Mennella, Julie A; Pepino, M Yanina; Lehmann-Castor, Sara M; Yourshaw, Lauren M
Year: 2010
Journal: Addiction (Abingdon, England)
PMID: 20148789
DOI: 10.1111/j.1360-0443.2009.02865.x
PMCID: PMC2993322

#	Section	Preview
0	Introduction	For children, the general rule seems to be the sweeter the better, a preference that evolved to…
1	Introduction	At some time during adolescence, the intensity of sweetness most preferred declines to levels…
2	Introduction	Whether a food tastes sweet and the emotions experienced upon ingestion are complex processes…
3	Introduction	Animal and human research has focused upon sweet preference as a potential phenotypic marker for…
4	Introduction	The discrepancies among research studies on adults could be due to several factors, including not…
5	Introduction	In the present study we tested young children before they experienced alcohol or tobacco, which…
6	Methods — Subjects	Mothers with children aged between 5 and 12 years were recruited for a research study on taste…
7	Methods — Family history of alcoholism and child depressive symptoms	The children were grouped according to their family history of alcoholism (FH) and depressive…
8	Methods — Family history of alcoholism and child depressive symptoms	Children were administered the 23-item Pictorial Depression Scale (PDS), a forced-choice,…
9	Methods — Family history of alcoholism and child depressive symptoms	Sixty-one additional children were excluded because they or one of their parents was adopted (n =…
10	Methods — Phenotyping for sucrose preferences, sweet food liking and sucrose analgesia	Children were tested individually following a 1-hour fast in a closed room designed specifically for…
11	Methods — Phenotyping for sucrose preferences, sweet food liking and sucrose analgesia	Secondly, we determined children's liking for sweet foods in daily life. Because children often…
12	Methods — Phenotyping for sucrose preferences, sweet food liking and sucrose analgesia	Thirdly, the analgesic properties of intra-oral sucrose were assessed with a cold pressor test for a…
13	Methods — Phenotyping for sucrose preferences, sweet food liking and sucrose analgesia	standardize skin temperature. At 1.5 minutes subjects placed in their mouths, without swallowing,…
14	Methods — Phenotyping for sucrose preferences, sweet food liking and sucrose analgesia	Pain threshold (time elapsed when the subject indicated discomfort by raising the non-immersed hand)…
15	Methods — Anthropometry and maternal characteristics	Children were weighed and measured for height, and then their body mass index (BMI; kg/m2) was…
16	Methods — Data analyses	Primary dependent variables were children's sucrose preference, sweet food liking score, pain…
17	Results — Subject characteristics	The four groups did not differ significantly in children's sex ratio (χ2(3) = 4.05, P = 0.26),…
18	Results — Subject characteristics	Approximately one-quarter of the children (27%; n = 81) were classified as PDEP. FHP children were…
19	Results — Subject characteristics	There were significant main effects of DEP and FH on maternal perceptions of child temperament…

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In this knowledge base

Title	Year	PMID
Endophenotypes for Alcohol Use Disorder: An Update on the Field.	2015	26236574
Genetics of sweet taste preferences.	2011	21743773

External

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