Genetic Influences on Alcoholism Risk: A Review of Adoption and Twin Studies.
paper
Cited
Public
- Authors
- Heath, Andrew C
- Year
- 1995
- Journal
- Alcohol health and research world
- PMID
- 31798109
- PMCID
- PMC6875767
Researchers have used two different strategies to determine the relative contributions of genes and shared environment to the development of alcoholism among family members: the adoption study and the twin study. Adoption studies compare the risk to biological relatives with the risk to adoptive relatives of alcoholics. Twin studies compare identical and fraternal pairs of twins reared in the same environment. Evidence indicates an important genetic influence on alcoholism risk; this influence appears as strong in women as in men. These results have been remarkably consistent despite major differences between research methods.
No figures extracted from this document.
1–20 of 36
Next →
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Molecular Effect of Variants in Serotonin Transporter Gene in Women with Alcohol Use Disorder. | Rychel M et al. | — | 2025 | → |
| Bitter taste function-related genes are implicated in the behavioral association between taste preference and ethanol preference in male mice. | Koh AP et al. | — | 2024 | → |
| Influence of sex in alcohol-related liver disease: Pre-clinical and clinical settings. | Bizzaro D et al. | — | 2023 | → |
| Hazardous drinking and alcohol use disorders. | MacKillop J et al. | — | 2022 | → |
| Alcohol in Psoriasis-From Bench to Bedside. | Szentkereszty-Kovács Z et al. | — | 2021 | → |
| The Etiologic, Theory-Based, Ontogenetic Hierarchical Framework of Alcohol Use Disorder: A Translational Systematic Review of Reviews. | Boness CL et al. | — | 2021 | → |
| Genetic Association and Expression Analyses of the Phosphatidylinositol-4-Phosphate 5-Kinase (PIP5K1C) Gene in Alcohol Use Disorder-Relevance for Pain Signaling and Alcohol Use. | Lee JS et al. | — | 2018 | → |
| Pharmacotherapy for alcohol use disorder: current and emerging therapies. | Swift RM et al. | — | 2015 | → |
| The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies. | Verhulst B et al. | — | 2015 | → |
| Genetics of alcoholism. | Edenberg HJ et al. | — | 2014 | → |
| Genotype-based association models of complex diseases to detect gene-gene and gene-environment interactions. | Lobach I et al. | — | 2014 | → |
| Genetics and alcoholism. | Edenberg HJ et al. | — | 2013 | → |
| The genetics of alcohol dependence. | Rietschel M et al. | — | 2013 | → |
| Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumption. | McBride WJ et al. | — | 2012 | → |
| Polymorphisms of the mu-opioid receptor and dopamine D4 receptor genes and subjective responses to alcohol in the natural environment. | Ray LA et al. | — | 2010 | → |
| Subjective responses to alcohol consumption as endophenotypes: advancing behavioral genetics in etiological and treatment models of alcoholism. | Ray LA et al. | — | 2010 | → |
| Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms. | Agrawal A et al. | — | 2009 | → |
| Parental alcoholism and offspring behavior problems: findings in Australian children of twins. | Waldron M et al. | — | 2009 | → |
| The dopamine D Receptor (DRD4) gene exon III polymorphism, problematic alcohol use and novelty seeking: direct and mediated genetic effects. | Ray LA et al. | — | 2009 | → |
| Affective circuitry and risk for alcoholism in late adolescence: differences in frontostriatal responses between vulnerable and resilient children of alcoholic parents. | Heitzeg MM et al. | — | 2008 | → |
| The short allele of the serotonin transporter promoter polymorphism influences relapse in alcohol dependence. | Pinto E et al. | — | 2008 | → |
| Pharmacotherapy for alcohol dependence: anticraving medications for relapse prevention. | Jung YC et al. | — | 2006 | → |
| Risk factors for alcohol misuse: examining heart rate reactivity to alcohol, alcohol sensitivity, and personality constructs. | Ray LA et al. | — | 2006 | → |
| Alcohol and gene interactions. | Whitfield JB | — | 2005 | → |
| Is cannabis a gateway drug? Testing hypotheses about the relationship between cannabis use and the use of other illicit drugs. | Hall WD et al. | — | 2005 | → |
| A polymorphism of the mu-opioid receptor gene (OPRM1) and sensitivity to the effects of alcohol in humans. | Ray LA et al. | — | 2004 | → |
| Biological and behavioral markers of alcohol sensitivity. | Fromme K et al. | — | 2004 | → |
| Gender differences in risk factors and consequences for alcohol use and problems. | Nolen-Hoeksema S | — | 2004 | → |
| Pharmacogenomics of alcohol response and addiction. | Enoch MA | — | 2003 | → |
| Effects of the interaction between genotype and environment. Research into the genetic epidemiology of alcohol dependence. | Heath AC et al. | — | 2002 | → |
| Gene-environment interaction effects on behavioral variation and risk of complex disorders: the example of alcoholism and other psychiatric disorders. | Heath AC et al. | — | 2002 | → |
| The heritability of alcohol abuse and dependence: a meta-analysis of behavior genetic research. | Walters GD | — | 2002 | → |
| An integrative approach for studying the etiology of alcoholism and other addictions. | Jacob T et al. | — | 2001 | → |
| Drug abuse and dependency: understanding gender differences in etiology and management. | Wasilow-Mueller S et al. | — | 2001 | → |
| Use of genetic analyses to refine phenotypes related to alcohol tolerance and dependence. | Crabbe JC | — | 2001 | → |
| Genetic and environmental influences on posttraumatic stress disorder, alcohol and drug dependence in twin pairs. | Xian H et al. | — | 2000 | → |
| Smoking and the genetic contribution to alcohol-dependence risk. | Madden PA et al. | — | 2000 | → |
| A case-control study on family history of liver cancer as a risk factor for hepatocellular carcinoma in North Italy. Brescia HCC Study. | Donato F et al. | — | 1999 | → |
| An assessment of the genetic relationship between alcohol metabolism and alcoholism risk in Australian twins of European ancestry. | Grant JD et al. | — | 1999 | → |
| A note on issues in meta-analysis for behavioral genetic studies using categorical phenotypes. | Ridenour TA et al. | — | 1999 | → |
| Possible linkage of alcoholism, monoamine oxidase activity and P300 amplitude to markers on chromosome 12q24. | Juo SH et al. | — | 1999 | → |