Onset of opportunity to use cannabis and progression from opportunity to dependence: Are influences consistent across transitions?

paper Cited Public

Authors: Hines, Lindsey A; Morley, Katherine I; Strang, John; Agrawal, Arpana; Nelson, Elliot C; Statham, Dixie; Martin, Nicholas G; Lynskey, Michael T
Year: 2016
Journal: Drug and alcohol dependence
PMID: 26811121
DOI: 10.1016/j.drugalcdep.2015.12.032
PMCID: PMC4946162

#	Section	Preview
0	1. INTRODUCTION	Cannabis is widely used, with cumulative lifetime incidence of use estimated to range from 6%-20% in…
1	1. INTRODUCTION	The first stage of drug involvement is having the opportunity to use (regardless of whether the…
2	1. INTRODUCTION	There is a developing body of research looking at the opportunity to use. Factors associated with…
3	1. INTRODUCTION	opportunity typically occurs in late childhood or early adolescence, lower parental involvement and…
4	1. INTRODUCTION	Amongst this existing evidence, there is little research examining the timing of opportunity to use…
5	1. INTRODUCTION	al., 2009), some mental health factors (Behrendt et al., 2011) and gender (Ridenour et al., 2006;…
6	1. INTRODUCTION	This paper aims to: Identify factors associated with earlier opportunity to use cannabisIdentify…
7	2. METHODS — 2.1 Sample	The sample was drawn from the Australian Twin Registry. From a pool of twin pairs born between 1972…
8	2. METHODS — 2.2 Assessment	Participants were assessed through computer-assisted telephone interviews which collected…
9	2. METHODS — 2.3 Measures — 2.3.1 Outcome Measures — 2.3.1.1 Opportunity to use cannabis	Participants were asked “have you ever been offered, or had the opportunity to use cannabis, even…
10	2. METHODS — 2.3 Measures — 2.3.1 Outcome Measures — 2.3.1.2 Cannabis dependence	Participants were classified as meeting lifetime criteria for DSM-IV cannabis dependence (American…
11	2. METHODS — 2.3 Measures — 2.3.1 Outcome Measures — 2.3.1.2 Cannabis dependence	Of those reporting lifetime opportunity to use cannabis, 10.9% (N=371) met criteria for cannabis…
12	2. METHODS — 2.3 Measures — 2.3.2 Covariates — 2.3.2.1 Demographic characteristics	Gender was determined through self-report.
13	2. METHODS — 2.3 Measures — 2.3.2 Covariates — 2.3.2.2 Childhood and parenting factors	Parental alcohol problems were determined through participant self-report of their mother or father…
14	2. METHODS — 2.3 Measures — 2.3.2 Covariates — 2.3.2.3	Parental drug problems were determined through participant self-report of their mother or father…
15	2. METHODS — 2.3 Measures — 2.3.2 Covariates — 2.3.2.4	Parental conflict was determined by participant responses to the questions “how often did your…
16	2. METHODS — 2.3 Measures — 2.3.2 Covariates — 2.3.2.5	Single parent family was determined by participants’ report of whether their mother or father was…
17	2. METHODS — 2.3 Measures — 2.3.2 Covariates — 2.3.2.6	Strict parenting was determined through participants response to the items “In your opinion, when…
18	2. METHODS — 2.3 Measures — 2.3.2 Covariates — 2.3.2.7	Childhood sexual abuse was recorded for individuals who reported being forced into sexual…
19	2. METHODS — 2.3 Measures — 2.3.2 Covariates — 2.3.2.8	Frequent childhood religious attendance was determined through participant self-report of their…

Citation	PMID	DOI	Status
Agrawal, A et al., Addiction, 2012, The co-occurring use and misuse of cannabis and tobacco: a review	22300456	10.1111/j.1360-0443.2012.03837.x	Cited
Agrawal, A et al., Drug Alcohol Depend, 2010, Mechanisms underlying the lifetime co-occurrence of tobacco and cannabis use in adolescent and young adult twins	20047801	10.1016/j.drugalcdep.2009.11.016	Cited
Agrawal, A et al., Drug Alcohol Depend, 2013, Do early experiences with cannabis vary in cigarette smokers?	23010290	10.1016/j.drugalcdep.2012.09.002	Cited
Anthony, JC, Cannabis Dependence: Its Nature, Consequences, and Treatment, 2006, The epidemiology of cannabis dependence	—	—	—
Behrendt, S et al., Drug Alcohol Depend, 2009, Transitions from first substance use to substance use disorders in adolescence: is early onset associated with a rapid escalation?	18768267	10.1016/j.drugalcdep.2008.06.014	Cited
Behrendt, S et al., Drug Alcohol Depend, 2012, The relevance of age at first alcohol and nicotine use for initiation of cannabis use and progression to cannabis use disorders	22071122	10.1016/j.drugalcdep.2011.10.013	Cited
Behrendt, S et al., Psychol. Med, 2011, The role of mental disorders in the risk and speed of transition to alcohol use disorders among community youth	20663258	10.1017/S0033291710001418	Cited
Bellera, CA et al., BMC Med. Res. Methodol, 2010, Variables with time-varying effects and the Cox model: some statistical concepts illustrated with a prognostic factor study in breast cancer	20233435	10.1186/1471-2288-10-20	Cited
Benjet, C et al., Drug Alcohol Depend, 2013, Chronic childhood adversity and stages of substance use involvement in adolescents	23276477	10.1016/j.drugalcdep.2012.12.002	Cited
Bucholz, KK et al., J. Stud. Alcohol Drugs, 1994, A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA	8189735	10.15288/jsa.1994.55.149	Primary
Caris, L et al., Drug Alcohol Depend, 2009, Opportunities to use drugs and stages of drug involvement outside the United States: evidence from the Republic of Chile	19328635	10.1016/j.drugalcdep.2008.12.004	Cited
Chen, C-Y et al., Addict. Behav, 2009, Early-onset drug use and risk for drug dependence problems	19022584	10.1016/j.addbeh.2008.10.021	Cited
Chen, C-Y et al., Am. J. Epidemiol, 2004, Religiosity and the earliest stages of adolescent drug involvement in seven countries of Latin America	15191935	10.1093/aje/kwh151	Cited
Chen, CY et al., Pediatrics, 2005, Influences of parenting practices on the risk of having a chance to try cannabis	15930226	10.1542/peds.2004-1926	Cited
Coffey, C et al., Addiction, 2000, Initiation and progression of cannabis use in a population-based Australian adolescent longitudinal study	11219371	10.1046/j.1360-0443.2000.951116798.x	Cited
Darke, S, Drug Alcohol Depend, 1998, Self-report among injecting drug users: a review	9787998	10.1016/s0376-8716(98)00028-3	Cited
Degenhardt, L et al., Drug Alcohol Rev, 2014, The Global burden of disease projects: what have we learned about illicit drug use and dependence and their contribution to the global burden of disease?	24251757	10.1111/dar.12088	Cited
Degenhardt, L et al., PLoS Med, 2008, Toward a global view of alcohol, tobacco, cannabis, and cocaine use: findings from the WHO World Mental Health Surveys	18597549	10.1371/journal.pmed.0050141	Cited
Diagnostic And Statistical Manual Of Mental Disorders: DSM-IV-TR, 4th Ed. Text Revision, 2000	—	—	—
Duncan, AE et al., Addiction, 2008, The association between cannabis abuse and dependence and childhood physical and sexual abuse: evidence from an offspring of twins design	18482422	10.1111/j.1360-0443.2008.02210.x	Cited
Efron, B, J. Am. Stat. Assoc, 1977, The efficiency of Cox’s Likelihood Function for censored data	—	—	—
Feingold, D et al., J. Affect. Disord, 2015, The association between cannabis use and mood disorders: a longitudinal study	25451420	10.1016/j.jad.2014.10.006	Cited
Gillespie, NA et al., Addiction, 2009, Pathways to cannabis abuse: a multi-stage model from cannabis availability, cannabis initiation and progression to abuse	19207351	10.1111/j.1360-0443.2008.02456.x	Cited
Heath, AC et al., Psychol. Med, 1997, Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men	9403910	10.1017/s0033291797005643	Cited
Hindocha, C et al., Drug Alcohol Depend, 2015, Associations between cigarette smoking and cannabis dependence: a longitudinal study of young cannabis users in the United Kingdom	25622777	10.1016/j.drugalcdep.2015.01.004	Cited
Hines, LA et al., Addict. Abingdon Engl, The association between speed of transition from initiation to subsequent use of cannabis and later problematic cannabis use, abuse and dependence	25917230	10.1111/add.12963	Cited
Hines, LA et al., Curr. Addict. Rep, Genetic and environmental interplay in adolescent substance use disorders	26301173	10.1007/s40429-015-0049-8	Cited
Johnson, TP et al., Addict. Abingdon Engl, 2001, The reliability of self-reported age of onset of tobacco, alcohol and illicit drug use	11487424	10.1046/j.1360-0443.2001.968118711.x	Cited
Lopez-Quintero, C et al., Drug Alcohol Depend, 2015, Prevalence and determinants of resistance to use drugs among adolescents who had an opportunity to use drugs	25659896	10.1016/j.drugalcdep.2015.01.015	Cited
Lynskey, MT et al., Twin Res. Hum. Genet, 2012, An Australian twin study of cannabis and other illicit drug use and misuse, and other psychopathology	22874079	10.1017/thg.2012.41	Cited
Miller, L et al., J. Am. Acad. Child Adolesc. Psychiatry, 2000, Religiosity and substance use and abuse among adolescents in the National Comorbidity Survey	10986817	10.1097/00004583-200009000-00020	Cited
National Drug Strategy Household Survey detailed report: 2013. Drug statistics series no. 28. Cat. no. PHE 183, 2014	—	—	—
Neumark, Y et al., Drug Alcohol Depend, 2012, Drug use opportunities as opportunities for drug use prevention: Bogota, Colombia a case in point	22018603	10.1016/j.drugalcdep.2011.09.022	Cited
Pacek, LR et al., J. Affect. Disord, 2013, The bidirectional relationships between alcohol, cannabis, co-occurring alcohol and cannabis use disorders with major depressive disorder: results from a national sample	23260381	10.1016/j.jad.2012.11.059	Cited
Patton, GC et al., BMJ, 2002, Cannabis use and mental health in young people: cohort study	12446533	10.1136/bmj.325.7374.1195	Cited
Pinchevsky, GM et al., Prev. Sci, 2011, Marijuana exposure opportunity and initiation during college: parent and peer influences	21870157	10.1007/s11121-011-0243-4	Cited
Preventing Mental, Emotional, and Behavioral Disorders Among Young People: Progress and Possibilities, The National Academies Collection: Reports funded by National Institutes of Health, 2009, National Research Council (US) and Institute of Medicine (US) Committee on the Prevention of Mental Disorders and Substance Abuse Among Children, Youth, and Young Adults: Research Advances and Promising Interventions	—	—	—
Reboussin, BA et al., Addict. Behav, 2015, Influences of behavior and academic problems at school entry on marijuana use transitions during adolescence in an African-American sample	25305658	10.1016/j.addbeh.2014.09.030	Cited
Ridenour, TA et al., Addict. Behav, 2006, Different lengths of times for progressions in adolescent substance involvement	16677774	10.1016/j.addbeh.2006.03.015	Cited
Sartor, CE et al., Addict. Behav, 2008, Psychiatric and familial predictors of transition times between smoking stages: results from an offspring-of-twins study	17900819	10.1016/j.addbeh.2007.09.002	Cited
Sartor, CE et al., Alcohol. Clin. Exp. Res, 2011, Reporting bias in the association between age at first alcohol use and heavy episodic drinking	21438885	10.1111/j.1530-0277.2011.01477.x	Cited
Sartor, CE et al., Drug Alcohol Depend, 2009, Common genetic influences on the timing of first use for alcohol, cigarettes, and cannabis in young African-American women	19261395	10.1016/j.drugalcdep.2008.12.013	Cited
Storr, CL et al., Drug Alcohol Depend, 2011, Childhood predictors of first chance to use and use of cannabis by young adulthood	21288658	10.1016/j.drugalcdep.2010.12.023	Cited
van Etten, ML et al., Addiction, 1999, Male-female differences in the earliest stages of drug involvement	10615725	10.1046/j.1360-0443.1999.949141312.x	Cited
Van Etten, ML et al., Drug Alcohol Depend, 1999, Comparative epidemiology of initial drug opportunities and transitions to first use: marijuana, cocaine, hallucinogens and heroin	10217551	10.1016/s0376-8716(98)00151-3	Cited
Vitaro, F et al., Int. J. Behav. Dev, 2009, The discordant MZ-twin method: one step closer to the holy grail of causality	—	—	—
Wagner, FA et al., J. Epidemiol, 2002, Into the world of illegal drug use: exposure opportunity and other mechanisms linking the use of alcohol, tobacco, marijuana, and cocaine	11994231	10.1093/aje/155.10.918	Cited
Wells, JE et al., Subst. Use Misuse, 2011, Cross-national comparisons of sex differences in opportunities to use alcohol or drugs, and the transitions to use	21417555	10.3109/10826084.2011.553659	Cited
Wittchen, HU et al., Int. J. Methods Psychiatr. Res, 2008, What are the high risk periods for incident substance use and transitions to abuse and dependence? Implications for early intervention and prevention	18543359	10.1002/mpr.254	Cited

In this knowledge base

Title	Year	PMID
Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families.	2018	28804966

External

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Persistent increased severity of cannabis use disorder symptoms in adolescents compared to adults: a one-year longitudinal study.	Lees R et al.	—	2025	→
Perspectives regarding cannabis use: Results from a qualitative study of individuals engaged in substance use treatment in Georgia and Connecticut.	Warnock CA et al.	—	2024	→
Impacts of recreational cannabis legalization on use and harms: A narrative review of sex/gender differences.	Matheson J et al.	—	2023	→
Prevalence and correlates of cannabis use disorder among Australians using cannabis products to treat a medical condition.	Mills L et al.	—	2022	→
Attitudes, Subjective Norms, and Perceived Behavioral Control Associated with Age of First Use of Cannabis among Adolescents.	Korn L et al.	—	2021	→
Cigarette Use and Cannabis Use Disorder Onset, Persistence, and Relapse: Longitudinal Data From a Representative Sample of US Adults.	Weinberger AH et al.	—	2021	→
Psychiatric Comorbidity and Addiction Severity Differences in Patients With ADHD Seeking Treatment for Cannabis or Cocaine Use Disorders.	Martínez-Luna N et al.	—	2021	→
The Relationship Between Childhood Physical and Sexual Abuse and Adolescent Cannabis Use: A Systematic Review.	De la Peña-Arteaga V et al.	—	2021	→
Assessing the public health effects of cannabis use: can legalization improve the evidence base?	Hickman M et al.	—	2020	→
Life-course trajectories of cannabis use: a latent class analysis of a New Zealand birth cohort.	Boden JM et al.	—	2020	→
Perceived Ease of Access and Age Attenuate the Association Between Marijuana Ad Exposure and Marijuana Use in Adolescents.	Turel O	—	2020	→
Probability and correlates of transition from cannabis use to DSM-5 cannabis use disorder: Results from a large-scale nationally representative study.	Feingold D et al.	—	2020	→
Monitoring young lifestyles (MyLife) - a prospective longitudinal quantitative and qualitative study of youth development and substance use in Norway.	Brunborg GS et al.	—	2019	→
Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families.	McCutcheon VV et al.	—	2018	→
Consideration of use opportunities, novel products, and user modes in cannabis monitoring, research, and policy: a response to the commentary.	Burdzovic Andreas J et al.	—	2018	→
Denise Kandel's classic work on the gateway sequence of drug acquisition.	Lynskey MT et al.	—	2018	→
Modelling opportunity: An examination of quadratic effects of adolescent Venezuelan substance use.	Croff JM et al.	—	2018	→
Overlap of heritable influences between cannabis use disorder, frequency of use and opportunity to use cannabis: trivariate twin modelling and implications for genetic design.	Hines LA et al.	—	2018	→
Commentary on Kosty et al. (2017): Understanding risk classes for cannabis use disorder requires knowledge of exposure, environment and genetic effects.	Hines LA	—	2017	→
Ready, willing, and able: the role of cannabis use opportunities in understanding adolescent cannabis use.	Burdzovic Andreas J et al.	—	2017	→
The relationship between initial route of heroin administration and speed of transition to daily heroin use.	Hines LA et al.	—	2017	→
Keep off the grass? Cannabis, cognition and addiction.	Curran HV et al.	—	2016	→