Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample.
paper
Cited
Public
- Authors
- Peer, Kyle; Rennert, Lior; Lynch, Kevin G; Farrer, Lindsay; Gelernter, Joel; Kranzler, Henry R
- Year
- 2013
- Journal
- Drug and alcohol dependence
- PMID
- 22884164
- DOI
- 10.1016/j.drugalcdep.2012.07.009
- PMCID
- PMC3727225
BACKGROUND: The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) will soon replace the DSM-IV, which has existed for nearly two decades. The changes in diagnostic criteria have important implications for research and for the clinical care of individuals with Substance Use Disorders (SUDs). METHODS: We used the Semi-Structured Assessment for Drug Dependence and Alcoholism to evaluate the lifetime presence of DSM-IV abuse and dependence diagnoses and DSM-5 mild, moderate, or severe SUDs for alcohol, cocaine, opioids, and cannabis in a sample of 7,543 individuals recruited to participate in genetic studies of substance dependence. RESULTS: Switches between diagnostic systems consistently resulted in a modestly greater prevalence for DSM-5 SUDs, based largely on the assignment of DSM-5 diagnoses to DSM-IV "diagnostic orphans" (i.e., individuals meeting one or two criteria for dependence and none for abuse, and thus not receiving a DSM-IV SUD diagnosis). The vast majority of these diagnostic switches were attributable to the requirement that only two of 11 criteria be met for a DSM-5 SUD diagnosis. We found evidence to support the omission from DSM-5 of the legal criterion due to its limited diagnostic utility. The addition of craving as a criterion in DSM-5 did not substantially affect the likelihood of an SUD diagnosis. CONCLUSION: The greatest advantage of DSM-5 for the diagnosis of SUDs appears to be its ability to capture diagnostic orphans. In this sample, changes reflected in DSM-5 had a minimal impact on the prevalence of SUD diagnoses.
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| Name | Type |
|---|---|
| abuse criterion local | phenotype |
| affected cases local | cohort |
| Agrawal et al. (2011) local | cohort |
| Agrawal et al. 2011 local | cohort |
| Agrawal et al., 2011 local | cohort |
| alcohol | phenotype |
| alcohol abuse | phenotype |
| alcohol dependence | phenotype |
| Alcohol Use Disorder | phenotype |
| alcohol use disorders | phenotype |
| Alcohol use severity continuum local | phenotype |
| amphetamine | drug |
| Amphetamine use disorder | phenotype |
| any SUD local | phenotype |
| Boscarino et al. 2011 local | cohort |
| cannabis use | phenotype |
| cannabis use disorder | phenotype |
| case-control sample | cohort |
| chronic pain | phenotype |
| cocaine | phenotype |
| cocaine disorder local | phenotype |
| cocaine use disorder | phenotype |
| Cocaine use disorders local | phenotype |
| college students | cohort |
| control subjects | cohort |
| craving | phenotype |
| Dependence symptoms | phenotype |
| diagnostic orphans | phenotype |
| Driving while intoxicated local | phenotype |
| drug dependence | phenotype |
| DSM-5 mild SUD local | phenotype |
| DSM-5 moderate or severe SUD local | phenotype |
| DSM-5 moderate SUD local | phenotype |
| DSM-5 severe SUD local | phenotype |
| DSM-IV | phenotype |
| DSM-IV abuse diagnosis local | phenotype |
| DSM-IV abuse or dependence local | phenotype |
| DSM-IV diagnostic orphan local | phenotype |
| DSM-IV substance abuse local | phenotype |
| full sample | cohort |
| Hasin et al. (2012) local | cohort |
| hazardous drinking | phenotype |
| hazardous use | phenotype |
| hazardous use criterion local | phenotype |
| heavy drinking | phenotype |
| Help-seeking behavior local | phenotype |
| Keyes et al. (2011) local | cohort |
| large SUD cohort local | cohort |
| legal criterion | phenotype |
| legal problems | phenotype |
| McLean Hospital | cohort |
| Medical University of South Carolina | cohort |
| Mewton et al. 2010 local | cohort |
| Mewton et al. (2011) local | cohort |
| Mewton et al. 2011 local | cohort |
| Moderate SUD local | phenotype |
| no SUD local | phenotype |
| opioid | drug |
| opioid dependence | phenotype |
| opioid disorder local | phenotype |
| Other 11 criteria local | phenotype |
| other criteria local | phenotype |
| population studies | cohort |
| Prescription drug local | drug |
| Prescription drug use disorder local | phenotype |
| present study | cohort |
| Proctor et al. 2012 local | cohort |
| proposed DSM-5 criteria changes local | phenotype |
| Severe SUD local | phenotype |
| Shmulewitz et al. (2010) local | cohort |
| SSADDA local | cohort |
| State prison inmates local | cohort |
| substance | phenotype |
| substance use | phenotype |
| Substance Use Disorder diagnoses local | phenotype |
| SUD diagnosis local | phenotype |
| SUD prevalence local | phenotype |
| trauma | phenotype |
| University of Connecticut Health Center | cohort |
| University of Pennsylvania | cohort |
| Yale University School of Medicine | cohort |
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