Neuronal generator patterns of olfactory event-related brain potentials in schizophrenia.

paper Cited Public

Authors: Kayser, Jürgen; Tenke, Craig E; Malaspina, Dolores; Kroppmann, Christopher J; Schaller, Jennifer D; Deptula, Andrew; Gates, Nathan A; Harkavy-Friedman, Jill M; Gil, Roberto; Bruder, Gerard E
Year: 2010
Journal: Psychophysiology
PMID: 20456657
DOI: 10.1111/j.1469-8986.2010.01013.x
PMCID: PMC3341093

#	Section	Preview
20	Methods — CSD Transform, Temporal PCA, and Statistical Analyses	Data from two meaningful, high-variance CSD factors corresponding to N1 and P2 were submitted to…
21	Methods — CSD Transform, Temporal PCA, and Statistical Analyses	It appears to be a fairly common, although incorrect, assumption that CSD methods necessarily…
22	Methods — CSD Transform, Temporal PCA, and Statistical Analyses	Another example would be a midline closed-field generator as described for a novelty vertex source…
23	Methods — CSD Transform, Temporal PCA, and Statistical Analyses	For analyses of the behavioral data, percentages of missed responses were submitted to a similar…
24	Results — Behavioral Data	The mean percentages of H2S stimuli that were missed (± SD) were 23.4 ± 17.5 and 44.9 ± 19.3…
25	Results — Average ERP and CSD Waveforms	To the best of our knowledge, no complete ERP waveform topography for olfactory stimuli has yet been…
26	Results — Average ERP and CSD Waveforms	the mastoid reference sites (TP9/10), however, it becomes obvious that recording sites along the…
27	Results — Average ERP and CSD Waveforms	N1 sink and P2 source amplitudes were greater to high- than low-intensity H2S stimuli in both…
28	Results — PCA Component Waveforms and Topographies	The first four PCA factors effectively explained all of the systematic CSD variance (82.6% after…
29	Results — PCA Component Waveforms and Topographies	Both healthy adults and schizophrenia patients had bilateral N1 sinks for the high odor…
30	Results — Repeated Measures ANOVA of PCA Factor Scores — N1 sink	At lateral centrotemporal sites (T7/8, C3/4, FC5/6, CP5/6) for factor 305, there was a highly…
31	Results — Repeated Measures ANOVA of PCA Factor Scores — N1 sink	The analysis for the frontopolar source (Fp1/2) accompanying the bilateral centrotemporal sinks for…
32	Results — Repeated Measures ANOVA of PCA Factor Scores — P2 source	At medial-lateral centroparietal sites (P3/4, P7/8, CP5/6, C3/4) for factor 630, there was also a…
33	Results — Repeated Measures ANOVA of PCA Factor Scores — P2 source	The analysis for the lateral frontotemporal sinks (FT9/10, F7/8) accompanying the parietal P2 for…
34	Discussion	The application of the CSD-PCA approach identified factors corresponding to the N1 and P2…
35	Discussion	perception. In contrast, the P2 source had a mid-parietal topography, with current sinks over…
36	Discussion	of other modalities than are piriform cortex and related olfactory cortical regions (Haberly, 2001).…
37	Discussion	of olfactory N1 sink and P2 source in the present odor detection paradigm would be the olfactory…
38	Discussion	The N1 sink and P2 source were greater to high than low concentrations of H2S, which is in accord…
39	Discussion	Schizophrenic patients had reduced N1 sink and P2 source amplitudes to the higher concentration of…

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Olfaction in the psychosis prodrome: electrophysiological and behavioral measures of odor detection.	2013	23856353
Generator localization by current source density (CSD): implications of volume conduction and field closure at intracranial and scalp resolutions.	2012	22796039

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