Polygenic risk scores: from research tools to clinical instruments.

paper Cited Public

Authors: Lewis, Cathryn M; Vassos, Evangelos
Year: 2020
Journal: Genome medicine
PMID: 32423490
DOI: 10.1186/s13073-020-00742-5
PMCID: PMC7236300

#	Section	Preview
40	Role of direct-to-consumer testing	Direct-to-consumer (DTC) genetic testing companies give consumers easy access to their genetic data,…
41	Role of direct-to-consumer testing	genetic testing, MyHeritage (https://www.myheritage.com/health/genetic-risk-reports) provides…
42	Role of direct-to-consumer testing	The accuracy and generalisability of any PRS model need to be validated with external data, but even…
43	Conclusions and future directions	Polygenic risk scores have moved from research discovery studies to clinical research studies (for…
44	Conclusions and future directions	of predictive ability in clinical populations, which may differ from research samples in disease…
45	Conclusions and future directions	One challenge of exploring the value of PRS within the clinical setting to predict the outcome, or…
46	Conclusions and future directions	An ultimate goal might be to have genotype data—and later whole-genome sequence data—integrated…
47	Conclusions and future directions	We focus on two limitations to the implementation of polygenic risk scores in clinical practice:…
48	Conclusions and future directions	In summary, we have made astounding biological advances in uncovering the genetic component to…

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Artificial intelligence-derived electrocardiographic aging and risk of atrial fibrillation: a multi-national study.	Cho S et al.	—	2025	→
Association between clock genes polygenic risk score for depression and obesity in a population with high burden of obesity.	Abdulkader HA et al.	—	2025	→
Association between genetic risk and adherence to the Dietary Approaches to Stop Hypertension diet for developing venous thromboembolism.	Li S et al.	—	2025	→
Association of Alzheimer's Disease Polygenic Risk Score with Concussion Severity and Recovery Metrics.	Dybing KM et al.	—	2025	→
Association of radiation-induced normal tissue toxicity with a high genetic risk for rheumatoid arthritis.	McWilliam A et al.	—	2025	→
Associations of polyunsaturated fatty acids and genetic predisposition with cardiovascular risk among hypertensive adults.	Li J et al.	—	2025	→
Benefits of Better Cardiovascular Health for Calcific Aortic Valve Stenosis Stratified by Polygenic Risk Score.	Zhu 朱岳鑫 Y et al.	—	2025	→
Body mass index modifies genetic susceptibility to high systolic blood pressure in adolescents and young adults: results from an 18-year longitudinal study.	Riglea T et al.	—	2025	→
Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations.	Wu Q et al.	—	2025	→
[Building precision psychiatry: why and how?]	Chaumette B et al.	—	2025	→
Calculating genetic risk scores directly from summary statistics with an application to type 1 diabetes.	Squires S et al.	—	2025	→
Can Polygenic Risk Scores for Metabolic Syndrome Contribute to Long-Term Syndrome Development in First-Episode Psychosis Patients? A Naturalistic 21-Year Follow-Up Study.	Cuesta MJ et al.	—	2025	→
Carotid artery atherosclerosis: mechanisms of instability and clinical implications.	Saba L et al.	—	2025	→
Choosing sweeteners wisely-nutrigenetic study on childhood obesity.	Qiu DW et al.	—	2025	→
Classification of schizophrenia, bipolar disorder and major depressive disorder with comorbid traits and deep learning algorithms.	Chen X et al.	—	2025	→
Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease: A clinical consensus statement of the ESC Council on Cardiovascular Genomics, the ESC Cardiovascular Risk Collaboration, and the European Association of Preventive Cardiology	Schunkert H et al.	—	2025	→
Combining the Risk: The Poly-Environmental Risk Score and Psychotic Symptoms in Adolescents.	Bouter DC et al.	—	2025	→
Comparing statistical learning methods for complex trait prediction from gene expression.	Klimkowski Arango N et al.	—	2025	→
Constructing a multi-ancestry polygenic risk score for uterine fibroids using publicly available data highlights need for inclusive genetic research.	Winters JLG et al.	—	2025	→
Contrasting genetic predisposition and diagnosis in psychiatric disorders: A multi-omic single-nucleus analysis of the human OFC.	Gerstner N et al.	—	2025	→
Cross-biobank generalizability and accuracy of electronic health record-based predictors compared to polygenic scores.	Detrois KE et al.	—	2025	→
Cross-species analysis of genetic architecture and polygenic risk scores for non-contact ACL rupture in dogs and humans.	Momen M et al.	—	2025	→
DBNX: A Machine Learning Method for Ensembling Polygenic Risk Scores and Non-Genetic Factors.	Yuan X et al.	—	2025	→
Defining next steps in the clinical implementation of polygenic scores: A landscape analysis of professional groups' perspectives.	Purvis R et al.	—	2025	→
Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis.	Manouchehrinia A et al.	—	2025	→
Developing a polygenic risk score for pelvic organ prolapse: a combined risk assessment approach in Chinese women.	Cheng X et al.	—	2025	→
Development and psychometric evaluation of a new genetic attitudes questionnaire in two national samples of United States residents.	Ksiazkiewicz A et al.	—	2025	→
Diabetes mellitus polygenic risk scores: heterogeneity and clinical translation.	Ortega HI et al.	—	2025	→
Dietary sugar intake, genetic susceptibility, and risk of dementia: A prospective cohort study.	An Y et al.	—	2025	→
Disentangling associations between complex traits and cell types with seismic.	Lai Q et al.	—	2025	→
Drinking motives and alcohol sensitivity mediate multidimensional genetic influences on alcohol use behaviors.	Savage JE et al.	—	2025	→
Early genetic screening and cardiac intervention in patients with cardiomyopathies in a multidisciplinary clinic.	Sadasivan C et al.	—	2025	→
Early life adversity and risk for non-communicable health outcomes: challenges and opportunities for a maturing field.	Jopling E et al.	—	2025	→
Effects of DNA methylation and polygenic scores on self-reported suicidal ideation in psychoses: no evidence of epigenetic basis of polygenic risk.	Nader G et al.	—	2025	→
Environmental Factors in the Etiology of Mental Disorders in the Czech Republic: Final Results.	Hosak L et al.	—	2025	→
Epigenome-wide association study, meta-analysis, and multiscore profiling of whole blood in Parkinson's disease.	Lie IH et al.	—	2025	→
Evaluating metabolome-wide causal effects on risk for psychiatric and neurodegenerative disorders.	Gilchrist L et al.	—	2025	→
Evaluating the Impact of Omega-3 Fatty Acids and Genetic Susceptibility on Atopic Dermatitis in Adults.	Mao R et al.	—	2025	→
Expanding our understanding of synucleinopathies: proteinopathy, proteinopenia, and lipidopathy.	Flores-León M et al.	—	2025	→
Exploring Random Forest in Genetic Risk Score Construction.	Venkat V et al.	—	2025	→
Exploring the application of deep learning methods for polygenic risk score estimation.	Squires S et al.	—	2025	→
Exploring the Varied Clinical Presentation of Pediatric Asthma through the Metabolome.	Mendez KM et al.	—	2025	→
Fair positive unlabeled learning for predicting undiagnosed Alzheimer's disease in diverse electronic health records.	Tran T et al.	—	2025	→
Foretelling the Future: Preimplantation Genetic Testing and the Coming of Polygenic Embryo Screening.	Smolarczyk R et al.	—	2025	→
From advanced imaging to molecular insights: the state of the art in omics for axial spondyloarthritis.	Arias-de la Rosa I et al.	—	2025	→
From classical approaches to artificial intelligence, old and new tools for PDAC risk stratification and prediction.	Farinella R et al.	—	2025	→
From variants to mechanisms: Neurogenomics in the post-GWAS era.	Margolis MP et al.	—	2025	→
Genal: a Python toolkit for genetic risk scoring and Mendelian randomization.	Rivier CA et al.	—	2025	→
Gene-Disease Relationships in Kidney Genetics.	Gitau V et al.	—	2025	→
Genes in context: path to more precise risk prediction in psychiatry?	Na PJ et al.	—	2025	→
Genetic Analysis and Predictive Modeling of COVID-19 Severity in a Hospital-Based Patient Cohort.	Alloza-Moral I et al.	—	2025	→
Genetic predeterminants and recent advancements in steatotic liver disease: A roadmap toward precision hepatology.	Kumar G et al.	—	2025	→
Genetic predisposition for negative affect predicts mental health burden during the COVID-19 pandemic.	Schowe AM et al.	—	2025	→
Genetic predisposition to high circulating levels of interleukin 6 and risk for Alzheimer's disease. Discovery and replication.	Charisis S et al.	—	2025	→
Genetic risk and transdiagnostic traits in anorexia nervosa, obsessive-compulsive disorder, and schizophrenia.	Aicoboaie S et al.	—	2025	→
Genetic Risk Factors in Childhood Psoriasis.	Schwarz CW et al.	—	2025	→
Genetic Risk for Open-Angle Glaucoma Subtypes Is Associated with Specific Visual Field Defect Classes.	Sekimitsu S et al.	—	2025	→
Genetics of intracerebral hemorrhage.	Kimball TN et al.	—	2025	→
Genetic Susceptibility to Neurodevelopmental Conditions Is Associated With Neonatal DNA Methylation Patterns in the General Population: An Individual Participant Data Meta-Analysis.	Schuurmans IK et al.	—	2025	→
Genetic Susceptibility to Type 2 Diabetes, Television Viewing, and Atherosclerotic Cardiovascular Disease Risk.	Wang M et al.	—	2025	→
Genetic Testing in Periodontitis: A Narrative Review on Current Applications, Limitations, and Future Perspectives.	Modafferi C et al.	—	2025	→
Genetic testing of common and rare variants in dementia patients from a memory clinic : Dementia-related genetic testing in memory clinic.	de Rojas I et al.	—	2025	→
Genome-wide association study of idiopathic epilepsy in the Italian Spinone dog breed.	Jenkins CA et al.	—	2025	→
Genome-wide functional annotation of variants: a systematic review of state-of-the-art tools, techniques and resources.	Pilalis E et al.	—	2025	→
Genomic approaches to explore susceptibility and pathogenesis of alcohol use disorder and alcohol-associated liver disease.	Norden-Krichmar TM et al.	—	2025	→
Genomic prediction with kinship-based multiple kernel learning produces hypothesis on the underlying inheritance mechanisms of phenotypic traits.	Raimondi D et al.	—	2025	→
Genomic Risk Prediction of Incident Atrial Fibrillation in Older Individuals Without Prior Cardiovascular Disease.	Fransquet PD et al.	—	2025	→
Genomics and the early diagnosis of lung cancer.	Pepe F et al.	—	2025	→
Genomics yields biological and phenotypic insights into bipolar disorder.	O'Connell KS et al.	—	2025	→
Genotypic and socioeconomic risks for depressive symptoms in two U.S. cohorts spanning early to older adulthood.	Sbarra DA et al.	—	2025	→
Geographic diversity of human liver cancers mirrors global social inequalities.	Cano L et al.	—	2025	→
Greater value add from electronic health records than polygenic risk scores for predicting myocardial infarction in machine learning.	Isgut M et al.	—	2025	→
Harnessing the power of genomics in hypertension: tip of the iceberg?	Naderi H et al.	—	2025	→
IBD Prediction Is Possible, but How Far Are We from Implementing It?	Turpin W et al.	—	2025	→
Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC-derived osteoblasts from Thoroughbred horses.	Palomino Lago E et al.	—	2025	→
Impact of lifestyle factors on adult-onset asthma in genetically high-risk individuals.	Kwon SY et al.	—	2025	→
Implications of gene × environment interactions in post-traumatic stress disorder risk and treatment.	Seah C et al.	—	2025	→
Improved breast cancer risk prediction using chromosomal-scale length variation.	Fatapour Y et al.	—	2025	→
Improved sex-specific cardiovascular risk prediction with multi-omics data in people with type 2 diabetes.	Xie R et al.	—	2025	→
Improvement of polygenic modeling of blood pressure traits using lifestyle information in the UK Biobank.	Tiezzi F et al.	—	2025	→
Improving neuroblastoma risk prediction through a polygenic risk score derived from genome-wide association study-identified loci.	Zhang W et al.	—	2025	→
Improving polygenic prediction from summary data by learning patterns of effect sharing across multiple phenotypes.	Kunkel D et al.	—	2025	→
Improving polygenic prediction from whole-genome sequencing data by leveraging predicted epigenomic features.	Zeng W et al.	—	2025	→
Influence and role of polygenic risk score in the development of 32 complex diseases.	Liu Y et al.	—	2025	→
Influence of lifestyle risk factors and genetic predisposition on metabolic syndrome risk in Korean adults.	Hwang SY et al.	—	2025	→
Influence of Polygenic Risk on Height and BMI in Adults With a 22q11.2 Microdeletion.	Ying S et al.	—	2025	→
Inherited Susceptibility to Cancer: Past, Present and Future.	Hodgson SV et al.	—	2025	→
Integrating Polygenic Risk Scores (PRS) for Personalized Diabetes Care: Advancing Clinical Practice with Tailored Pharmacological Approaches.	Singh O et al.	—	2025	→
Intricate interactions between fine-scale genetic structure, lifestyle, and dietary habits in the Japanese population.	Chen Y et al.	—	2025	→
Investigating Gene-Environment Interplay Between Bereavement and Polygenic Risk for Attention-Deficit/Hyperactivity Disorder on Externalizing Behaviors During Adolescence.	Espinosa Dice AL et al.	—	2025	→
Investigating the sources of variable impact of pathogenic variants in monogenic metabolic conditions.	Wei A et al.	—	2025	→
JointPRS: A data-adaptive framework for multi-population genetic risk prediction incorporating genetic correlation.	Xu L et al.	—	2025	→
Knowledge, attitudes and demand toward cardiovascular polygenic risk testing in clinical practice: cross-sectional survey of patients.	Brar S et al.	—	2025	→
Leveraging genotypes and phenotypes to implement precision medicine in hidradenitis suppurativa management.	Petukhova L et al.	—	2025	→
Leveraging global genetics resources to enhance polygenic prediction across ancestrally diverse populations.	Pain O	—	2025	→
Long-term cardiovascular risk in women with hypertensive disorders of pregnancy: Insights from polygenic risk scores.	Kivioja A et al.	—	2025	→
Machine Learning-Based Prediction of Gout Using Polygenic Risk Scores and Clinical Variables: A Korean Cohort Study.	Kwak DH et al.	—	2025	→
Machine learning in Alzheimer's disease genetics.	Bracher-Smith M et al.	—	2025	→
Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer.	Chen C et al.	—	2025	→
MIXED MODELING APPROACH FOR CHARACTERIZING THE GENETIC EFFECTS IN A LONGITUDINAL PHENOTYPE.	Zhang P et al.	—	2025	→
Modeling gene interactions in polygenic prediction via geometric deep learning.	Li H et al.	—	2025	→
Multiomics insight into disease trajectories of cardiometabolic diseases and cancer.	Jiang X et al.	—	2025	→
Multi-omics profiling reveals altered mitochondrial metabolism in adipose tissue from patients with metabolic dysfunction-associated steatohepatitis.	Castañé H et al.	—	2025	→
Multivariable regression models improve accuracy and sensitive grading of antibiotic resistance mutations in Mycobacterium tuberculosis.	Kulkarni SG et al.	—	2025	→
Nanopore adaptive sampling accurately detects nucleotide variants and improves the characterization of large-scale rearrangement for the diagnosis of cancer predisposition.	Chevrier S et al.	—	2025	→
Navigating the Future of Polygenic Risk Scores: Insights from Child and Adolescent Psychiatrists.	Trotter PM et al.	—	2025	→
Neurostructural Correlates of Polygenic Risk for Coronary Artery Disease in Relation to Youth Bipolar Disorder.	Kulkarni NP et al.	—	2025	→
Nonlinearity and sex differences in the performance of a polygenic risk score for juvenile idiopathic arthritis.	Haftorn KL et al.	—	2025	→
Novel genetic loci and functional properties of immune-related genes for colorectal cancer survival in Korea.	Yun D et al.	—	2025	→
Novel genetic variants associated with stable isotope-based vitamin B<sub>12</sub> bioavailability measurements in healthy Indian adults.	Sivadas A et al.	—	2025	→
Novel Multimodal Precision Medicine Approaches and the Relevance of Developmental Trajectories in Bipolar Disorder.	Smeland OB et al.	—	2025	→
Obstructive sleep apnea mediates genetic risk of Diabetes Mellitus in Hispanic and Latino communities.	Hrytsenko Y et al.	—	2025	→
Optimization of multi-ancestry polygenic risk score disease prediction models.	Lerga-Jaso J et al.	—	2025	→
Partially connected neural networks for complex trait prediction: application to human height.	Weng H et al.	—	2025	→
Patient perspectives after receiving simulated preconception polygenic risk scores (PRS) for family planning.	Katz M et al.	—	2025	→
Perceived risk of type 2 diabetes: Using linked genomic, clinical and questionnaire data to understand the potential use of genetic risk tools in British South Asians.	Law JH et al.	—	2025	→
PGxDB: an interactive web-platform for pharmacogenomics research.	Duong Nguyen TT et al.	—	2025	→
Pharmacogenetic Panel Testing: A Review of Current Practice and Potential for Clinical Implementation.	Mosch R et al.	—	2025	→
Polygenic and Polyenvironment Interplay in Schizophrenia-Spectrum Disorder and Affective Psychosis; the EUGEI First Episode Study.	Rodriguez V et al.	—	2025	→
Polygenic modifiers impact penetrance and expressivity in telomere biology disorders.	Poeschla M et al.	—	2025	→
Polygenic prediction of cardiorespiratory fitness in the Trøndelag health study (HUNT).	Øvretveit K et al.	—	2025	→
Polygenic predisposition to transdiagnostic symptom dimensions and treatment outcomes across psychiatric disorders.	Abondio P et al.	—	2025	→
Polygenic Risk, Modifiable Lifestyle Behaviors, and Metabolic Factors: Associations with HDL-C, Triglyceride Levels, and Cardiovascular Risk.	Chermon D et al.	—	2025	→
Polygenic Risk Prediction for Normal-Tension Glaucoma.	Marzban M et al.	—	2025	→
Polygenic risk score and clinical factors predict incident idiopathic pulmonary arterial hypertension.	Hu S et al.	—	2025	→
Polygenic Risk Score for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis: A Narrative Review.	Kanda T et al.	—	2025	→
Polygenic risk score prediction accuracy convergence.	Henches L et al.	—	2025	→
Polygenic risk score predicts pathologically confirmed cerebral amyloid angiopathy.	Pyun JM et al.	—	2025	→
Polygenic risk scores and embryonic screening: considerations for regulation.	Haining CM et al.	—	2025	→
Polygenic risk scores in healthcare contexts: what's the scope? An interview study of European healthcare providers and researchers' perspectives on ethical challenges.	Andreoli L et al.	—	2025	→
Polygenic risk scores in routine genetic diagnostics: what lies ahead?	Lauffer P et al.	—	2025	→
Polygenic risk score to the rescue of monogenic diseases? The case of epilepsy.	De Sainte Agathe JM et al.	—	2025	→
Polygenic Risks for Depression and Neural Responses to Reward and Punishment in Young Adults.	Chen Y et al.	—	2025	→
Polygenic score from MODY genes is associated with type 1 diabetes and disease characteristics.	Catamo E et al.	—	2025	→
Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease.	Kurniansyah N et al.	—	2025	→
Population-specific genetic-risk scores enable improved prediction of mortality within 28 days of sepsis onset: a retrospective Taiwanese cohort study.	Hsieh MS et al.	—	2025	→
Population stratification using MASLD polygenic risk score improves severe liver disease prediction by clinical fibrosis scores.	Liu Z et al.	—	2025	→
Precision medicine in substance use disorders: Integrating behavioral, environmental, and biological insights.	Guerrin CGJ et al.	—	2025	→
Predicting the incidence of depression in adolescence using a sociodemographic risk score: prospective follow-up of the IDEA-RiSCo study.	Piccin J et al.	—	2025	→
Predictive capabilities of polygenic scores in an East-Asian population-based cohort: the Singapore Chinese health study.	Chang X et al.	—	2025	→
Predictive performance for alcohol use disorder of polygenic scores based on the general addiction risk factor and problematic alcohol use.	Pérez-Gutiérrez AM et al.	—	2025	→
Primary care providers' experience and satisfaction with personalised breast cancer screening risk communication: a descriptive cross-sectional study.	Omeranovic A et al.	—	2025	→
Prognostic Significance and Immune Environment Analysis Using PANoptosis Molecular Clustering in Gastric Cancer.	Qu C et al.	—	2025	→
Prolonged loneliness and risk of incident cognitive decline and dementia: A two-cohort study.	Ren Z et al.	—	2025	→
Prospective associations between muscle strength and genetic susceptibility to type 2 diabetes with incident type 2 diabetes: a UK Biobank study.	Wang M et al.	—	2025	→
Prospective associations of genetic susceptibility to high blood pressure and muscle strength with incident cardiovascular disease outcomes.	Wang M et al.	—	2025	→
Protein Associations With Alcohol Consumption and Genetic Risk for Alcohol-Related Sociomedical Conditions.	Drouard G et al.	—	2025	→
Psychiatric Polygenic Risk Scores and Week-by-Week Symptomatic Status in Youth with Bipolar Disorder: An Exploratory Study.	Jiang X et al.	—	2025	→
PTL-PRS: an R package for transfer learning of polygenic risk scores with pseudovalidation.	Cho B et al.	—	2025	→
Quantifying the versatility of routinely measured prognostic factors.	Innes H et al.	—	2025	→
Ramp Sequence May Explain Synonymous Variant Association with Alzheimer's Disease in the Paired Immunoglobulin-like Type 2 Receptor Alpha (PILRA).	Miller JB et al.	—	2025	→
RatXcan: A framework for cross-species integration of genome-wide association and gene expression data.	Santhanam N et al.	—	2025	→
Real-time dynamic polygenic prediction for streaming data.	Tubbs JD et al.	—	2025	→
Reproducibility of genetic risk factors identified for long COVID using combinatorial analysis across US and UK patient cohorts with diverse ancestries.	Sardell J et al.	—	2025	→
Research Review: A review of the past decade of family and genomic studies on adolescent mental health.	Morneau-Vaillancourt G et al.	—	2025	→
Sex differences in predicting dyslipidemia using polygenic risk score with fatty liver index and fibrotic nonalcoholic steatohepatitis index.	Kim S et al.	—	2025	→
Sex-specific genetic effects on susceptibility to idiopathic pulmonary fibrosis.	Leavy OC et al.	—	2025	→
Shedding Light on Antisocial Behavior Through Genetically Informed Research.	Pezzoli P et al.	—	2025	→
Sparse polygenic risk score inference with the spike-and-slab LASSO.	Song J et al.	—	2025	→
Statistical construction of calibrated prediction intervals for polygenic score-based phenotype prediction.	Xu C et al.	—	2025	→
STICI: Split-Transformer with integrated convolutions for genotype imputation.	Mowlaei ME et al.	—	2025	→
The accuracy of polygenic score models for BMI and Type II diabetes in the Native Hawaiian population.	Lo YC et al.	—	2025	→
The current landscape of personalised preventive approaches for non-communicable diseases: A scoping review.	Farina S et al.	—	2025	→
The effects of polygenic risks for alcohol misuse on negative emotion processing in young adult binge drinkers.	Chen Y et al.	—	2025	→
The Evolving Landscape of Functional Models of Autism Spectrum Disorder.	Ranjan J et al.	—	2025	→
The genetic landscape of pediatric postural orthostatic tachycardia syndrome.	Qu H et al.	—	2025	→
The interaction between genetic predicted gut microbiome abundance and particulate matter on the risk of incident asthma in adults.	Zhang H et al.	—	2025	→
The Polygenic Nature of Multiple Sclerosis: Genetic Variants, Immunological Modulation, and Environmental Connections.	Khan Z et al.	—	2025	→
The quest for a complete understanding of the human genome.	Abou Tayoun A et al.	—	2025	→
The Role of Genetics in Human Oral Health: A Systematic-Narrative Review.	Joy-Thomas A et al.	—	2025	→
The SINTER study: A Recall-by-Genotype design with multidimensional musculoskeletal phenotyping across internal-medicine outpatient clinics	Koromani F et al.	—	2025	—
Toward whole-genome inference of polygenic scores with fast and memory-efficient algorithms.	Zabad S et al.	—	2025	→
Twin Study Provides Heritability Estimates for 2321 Plasma Proteins and Assesses Missing SNP Heritability.	Drouard G et al.	—	2025	→
Type 2 Diabetes Polygenic Risk Score Interactions with Lifestyle Risk Factors in Black Americans.	Scadden AW et al.	—	2025	→
UKB-MDRMF: a multi-disease risk and multimorbidity framework based on UK biobank data.	Jiang Y et al.	—	2025	→
Understanding Genetic Screening: Harnessing Health Information to Prevent Disease Risks.	Lee CL et al.	—	2025	→
Understanding inherited cardiomyopathies: clinical aspects and genetic determinants.	Yigit G et al.	—	2025	→
Understanding the Emergence of Schizophrenia in the Light of Human Evolution: New Perspectives in Genetics.	Sandroni V et al.	—	2025	→
Understanding the potential contribution of polygenic risk scores to the prediction of gestational and type 2 diabetes in women from British Pakistani and Bangladeshi groups: a cohort study in Genes and Health.	Zöllner J et al.	—	2025	→
Unlocking the potential: advancements and applications of gene therapy in severe disorders.	Ingle RG et al.	—	2025	→
Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management.	Mittal R et al.	—	2025	→
Unveiling Novel Traits Associated with Ulcerative Colitis via Phenome-Wide Associations Enhanced by Polygenic Risk Statistics.	Wu Y et al.	—	2025	→
Validate association of gene loci and establish genetic risk prediction models for late-onset Alzheimer's disease in Chinese populations.	Li F et al.	—	2025	→
Variational autoencoder-based model improves polygenic prediction in blood cell traits.	Li X et al.	—	2025	→
Weighing the evidence on costs and benefits of polygenic risk-based approaches in clinical practice: A systematic review of economic evaluations.	Siena LM et al.	—	2025	→
Accurate and cost-effective generation of a genetic risk score direct from blood lysates.	Locke JM et al.	—	2024	→
A combination of red and processed meat intake and polygenic risk score influences the incidence of hyperuricemia in middle-aged Korean adults.	Lee S et al.	—	2024	→
A de novo ARIH2 gene mutation was detected in a patient with autism spectrum disorders and intellectual disability.	Vinci M et al.	—	2024	→
Advances in drug-induced liver injury research: in vitro models, mechanisms, omics and gene modulation techniques.	Guo K et al.	—	2024	→
Age at Natural Menopause, Reproductive Lifespan, and the Risk of Late-Onset Psoriasis and Psoriatic Arthritis in Women: A Prospective Cohort Study.	Xiao Y et al.	—	2024	→
Air pollutants, genetic susceptibility and the risk of schizophrenia: large prospective study.	Liu R et al.	—	2024	→
Analysis of comprehensive biomolecules in critically ill patients via bioinformatics technologies.	Matsumoto H et al.	—	2024	→
Anemia, blood cell indices, genetic correlations, and brain structures: A comprehensive analysis of roles in Parkinson's disease risk.	Zuo CY et al.	—	2024	→
An externally validated resting-state brain connectivity signature of pain-related learning.	Kincses B et al.	—	2024	→
A perspective on genetic and polygenic risk scores-advances and limitations and overview of associated tools.	Schwarzerova J et al.	—	2024	→
A Plea for Nuance: Should People with a Family History of Bipolar Disorder Be Excluded from Clinical Trials of Psilocybin Therapy?	Downey AE et al.	—	2024	→
APOE ε4 carriage associates with improved myocardial performance from adolescence to older age.	Topriceanu CC et al.	—	2024	→
A polygenetic risk score combined with environmental factors better predict susceptibility to hepatocellular carcinoma in Chinese population.	Zou Y et al.	—	2024	→
A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry.	Schwantes-An TH et al.	—	2024	→
A polygenic risk score model for psoriasis based on the protein interactions of psoriasis susceptibility loci.	Antonatos C et al.	—	2024	→
A polygenic score method boosted by non-additive models.	Ohta R et al.	—	2024	→
Applications of genome sequencing as a single platform for clinical constitutional genetic testing.	Yang Y et al.	—	2024	→
Applied pharmacogenetics to predict response to treatment of first psychotic episode: study protocol.	Mas S et al.	—	2024	→
A review of the advances in understanding the genetic basis of spondylarthritis and emerging clinical benefit.	Stadler M et al.	—	2024	→
"Are we not going too far?": Socio-ethical considerations of preimplantation genetic testing using polygenic risk scores according to healthcare professionals.	Siermann M et al.	—	2024	→
Assessing the efficacy of target adaptive sampling long-read sequencing through hereditary cancer patient genomes.	Nakamura W et al.	—	2024	→
Association between irritable bowel syndrome and Parkinson's disease by Cohort study and Mendelian randomization analysis.	Wang ZY et al.	—	2024	→
Association between metabolic syndrome and kidney cancer risk: a prospective cohort study.	Wang L et al.	—	2024	→
Association between psychiatric admissions in patients with schizophrenia and IL-6 plasma levels polygenic score.	Facal F et al.	—	2024	→
Association of Cardiovascular Health with the Incidence of Venous Thromboembolism: A Prospective Study of 275,149 Participants from the UK Biobank.	Liang B et al.	—	2024	→
Associations between attention-deficit hyperactivity disorder genetic liability and ICD-10 medical conditions in adults: utilizing electronic health records in a Phenome-Wide Association Study.	Haan E et al.	—	2024	→
Associations between frailty, genetic predisposition, and chronic kidney disease risk in middle-aged and older adults: A prospective cohort study.	Yang H et al.	—	2024	→
Associations of Self-Reported Race, Social Determinants of Health, and Polygenic Risk With Coronary Heart Disease.	Norland K et al.	—	2024	→
A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score (PRS) Release.	Thompson DJ et al.	—	2024	→
Balancing the efforts of chart review and gains in PRS prediction accuracy: An empirical study.	Lei Y et al.	—	2024	→
Bipolar patients display stoichiometric imbalance of gene expression in post-mortem brain samples.	Holmgren A et al.	—	2024	→
Blood protein assessment of leading incident diseases and mortality in the UK Biobank.	Gadd DA et al.	—	2024	→
Brainwide Risk Scores: An Example of Psychiatric Risk Prediction From Resting-State Functional Magnetic Resonance Imaging.	Schleifer CH	—	2024	→
Characterization of brain resilience in Alzheimer's disease using polygenic risk scores and further improvement by integrating mitochondria-associated loci.	Xu X et al.	—	2024	→
Characterizing the Relationship between Expression Quantitative Trait Loci (eQTLs), DNA Methylation Quantitative Trait Loci (mQTLs), and Breast Cancer Risk Variants.	Ho PJ et al.	—	2024	→
Childhood maltreatment and health in the UK Biobank: triangulation of outcome-wide and polygenic risk score analyses.	Espinosa Dice AL et al.	—	2024	→
Cholesterol associated genetic risk score and acute coronary syndrome in Czech males.	Hubacek JA et al.	—	2024	→
Clinical characteristics of patients with a family history of psoriasis: an observational epidemiological study in Chinese Han population.	Cao L et al.	—	2024	→
Clinical features of prostate cancer by polygenic risk score.	Spears C et al.	—	2024	→
Colorectal Cancer Risk between Mendelian and Non-Mendelian Inheritance.	Hibler EA et al.	—	2024	→
Commonly used genomic arrays may lose information due to imperfect coverage of discovered variants for autism spectrum disorder.	Yao M et al.	—	2024	→
Common polygenic variation in the early medication change (EMC) cohort affects disorder risk, but not the antidepressant treatment response.	Müller S et al.	—	2024	→
Comprehensive Evaluation of the Genetic Basis of Keratoconus: New Perspectives for Clinical Translation.	Cerván-Martín M et al.	—	2024	→
Considerations for the application of polygenic scores to clinical care of individuals with substance use disorders.	Kember RL et al.	—	2024	→
Correlates of Risk for Disinhibited Behaviors in the Million Veteran Program Cohort.	Barr PB et al.	—	2024	→
Cross-population applications of genomics to understand the risk of multifactorial traits involving inflammation and immunity.	Alamad B et al.	—	2024	→
Deciphering the impact of genomic variation on function.	IGVF Consortium	—	2024	→
Deciphering the Interplay between Genetic Risk Scores and Lifestyle Factors on Individual Obesity Predisposition.	Chermon D et al.	—	2024	→
Decoding the genetic landscape of autism: A comprehensive review.	Al-Beltagi M et al.	—	2024	→
Dementia with Lewy Bodies: Genomics, Transcriptomics, and Its Future with Data Science.	Goddard TR et al.	—	2024	→
Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples.	Elam KK et al.	—	2024	→
[Development of prognostic clinical and genetic models of the risk of low bone mineral density using neural network training].	Yalaev BI et al.	—	2024	→
Diet-microbiota associations in gastrointestinal research: a systematic review.	Duncanson K et al.	—	2024	→
Effects and interaction of single nucleotide polymorphisms at the pharmacokinetic/pharmacodynamic site: insights from the Rotterdam study into metformin clinical response and dose titration.	Mohammadi Jouabadi S et al.	—	2024	→
Efficacy of federated learning on genomic data: a study on the UK Biobank and the 1000 Genomes Project.	Kolobkov D et al.	—	2024	→
EmbedGEM: a framework to evaluate the utility of embeddings for genetic discovery.	Mukherjee S et al.	—	2024	→
Enhancing portability of trans-ancestral polygenic risk scores through tissue-specific functional genomic data integration.	Crone B et al.	—	2024	→
Enhancing the Prediction Power of Polygenic Risk Scores in Genetically Diverse Coronary Heart Disease.	Henry J et al.	—	2024	→
Epigenetic scores derived in saliva are associated with gestational age at birth.	Mckinnon K et al.	—	2024	→
Epigenomic partitioning of a polygenic risk score for asthma reveals distinct genetically driven disease pathways.	Stikker B et al.	—	2024	→
Evaluation of polygenic scoring methods in five biobanks shows larger variation between biobanks than methods and finds benefits of ensemble learning.	Monti R et al.	—	2024	→
Exome functional risk score and brain connectivity can predict social adaptability outcome of children with autism spectrum disorder in 4 years' follow up.	Luo T et al.	—	2024	→
Exploring the genetics of airflow limitation in lung function across the lifespan - a polygenic risk score study.	Hernandez-Pacheco N et al.	—	2024	→
Exploring the impact and utility of genomic sequencing in established CKD.	Jefferis J et al.	—	2024	→
Exploring the role of underrepresented populations in polygenic risk scores for neurodegenerative disease risk prediction.	Step K et al.	—	2024	→
Factor analysis of lifetime psychopathology and its brain morphometric and genetic correlates in a transdiagnostic sample.	Krug A et al.	—	2024	→
Fast and scalable ensemble learning method for versatile polygenic risk prediction.	Chen T et al.	—	2024	→
Functional genomics in inborn errors of immunity.	Hurabielle C et al.	—	2024	→
GAUSS: a summary-statistics-based R package for accurate estimation of linkage disequilibrium for variants, Gaussian imputation, and TWAS analysis of cosmopolitan cohorts.	Lee D et al.	—	2024	→
Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence.	Kranzler HR et al.	—	2024	→
Generalizability of polygenic prediction models: how is the R<sup>2</sup> defined on test data?	Staerk C et al.	—	2024	→
Gene therapy and kidney diseases.	Tavakolidakhrabadi N et al.	—	2024	→
Genetic and Non-Genetic Contributions to Eosinophilic Granulomatosis with Polyangiitis: Current Knowledge and Future Perspectives.	Treccani M et al.	—	2024	→
Genetic Causes of Nephrotic Syndrome and Focal and Segmental Glomerulosclerosis.	Caparali EB et al.	—	2024	→
Genetic contribution to disease-course severity and progression in the SUPER-Finland study, a cohort of 10,403 individuals with psychotic disorders.	Kämpe A et al.	—	2024	→
Genetic risk score for insulin resistance based on gene variants associated to amino acid metabolism in young adults.	Lares-Villaseñor E et al.	—	2024	→
Genetic risk score in patients with the APOE2/E2 genotype as a predictor of familial dysbetalipoproteinemia.	Satny M et al.	—	2024	→
Genetic risk scores associated with temperament clusters in Finnish depression patients.	Salminen SP et al.	—	2024	→
Genetic risk stratification and risk factors of early menopause in women: a multi-center study utilizing polygenic risk scores.	Zhong W et al.	—	2024	→
Genetics of hypertension-related sex differences and hypertensive disorders of pregnancy.	Nurkkala J et al.	—	2024	→
Genetic variants of <i>LRRC8C</i>, <i>OAS2</i>, and <i>CCL25</i> in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.	Lu G et al.	—	2024	→
Genome Sequencing in an Individual Presenting with 22q11.2 Deletion Syndrome and Juvenile Idiopathic Arthritis.	de Oliveira-Sobrinho RP et al.	—	2024	→
Genomes in clinical care.	Riess O et al.	—	2024	→
Genome-wide polygenic risk score for rheumatoid arthritis prediction in postmenopausal women.	Xu Y et al.	—	2024	→
Genomic insights for personalised care in lung cancer and smoking cessation: motivating at-risk individuals toward evidence-based health practices.	Chen T et al.	—	2024	→
Genotype × environment interactions in gene regulation and complex traits.	Boye C et al.	—	2024	→
GWAS-based polygenic risk scoring for predicting cerebral artery dissection in the Chinese population.	Zhang S et al.	—	2024	→
Identifying and characterizing disease subpopulations that most benefit from polygenic risk scores.	Isgut M et al.	—	2024	→
Impact of genetic predisposition to late-onset neurodegenerative diseases on early life outcomes and brain structure.	Ogonowski NS et al.	—	2024	→
Impact of the trans-ancestry polygenic risk score on type 2 diabetes risk, onset age and progression among population in Taiwan.	Wang SH et al.	—	2024	→
Imputation Server PGS: an automated approach to calculate polygenic risk scores on imputation servers.	Forer L et al.	—	2024	→
Incidence of Dementia and Alzheimer's Disease, Genetic Susceptibility, and Grip Strength Among Older Adults.	Kim Y et al.	—	2024	→
Inclusiveness of the All of Us Research Program improves polygenic risk scores and fosters genomic medicine for all.	Kidenya BR et al.	—	2024	→
Inconsistent embryo selection across polygenic score methods.	Namba S et al.	—	2024	→
Incorporating polygenic risk into the Leicester Risk Assessment score for 10-year risk prediction of type 2 diabetes.	Liu X et al.	—	2024	→
Induced Pluripotent Stem Cells as a Possible Approach for Exploring the Pathophysiology of Polycystic Ovary Syndrome (PCOS).	Khatun M et al.	—	2024	→
Integrating Genome-Wide Polygenic Risk Scores With Nongenetic Models to Predict Surgical Site Infection After Total Knee Arthroplasty Using United Kingdom Biobank Data.	Chen PY et al.	—	2024	→
Integrating Multi-Organ Imaging-Derived Phenotypes and Genomic Information for Predicting the Occurrence of Common Diseases.	Liu M et al.	—	2024	→
Integration of a polygenic score into guideline-recommended prediction of cardiovascular disease.	Li L et al.	—	2024	→
Integration of polygenic and gut metagenomic risk prediction for common diseases.	Liu Y et al.	—	2024	→
Interactions between Polygenic Risk of Obesity and Dietary Factors on Anthropometric Outcomes: A Systematic Review and Meta-Analysis of Observational Studies.	Han HY et al.	—	2024	→
In the context of the triple burden of malnutrition: A systematic review of gene-diet interactions and nutritional status.	Tan PY et al.	—	2024	→
Joint modeling of gene-environment correlations and interactions using polygenic risk scores in case-control studies.	Wang Z et al.	—	2024	→
Lessons and Applications of Omics Research in Diabetes Epidemiology.	Yu G et al.	—	2024	→
Long read sequencing on its way to the routine diagnostics of genetic diseases.	Olivucci G et al.	—	2024	→
Machine learning reveals heterogeneous associations between environmental factors and cardiometabolic diseases across polygenic risk scores.	Naito T et al.	—	2024	→
Metabolic dysfunction-associated steatotic liver disease heterogeneity: Need of subtyping.	Habib S	—	2024	→
Metabolomic and genomic prediction of common diseases in 700,217 participants in three national biobanks.	Nightingale Health Biobank Collaborative Group	—	2024	→
Methylation profiles at birth linked to early childhood obesity.	Lariviere D et al.	—	2024	→
Nongenetic and Genetic Factors Associated with White Matter Brain Aging: Exposome-Wide and Genome-Wide Association Study.	Feng L et al.	—	2024	→
Optimizing and benchmarking polygenic risk scores with GWAS summary statistics.	Zhao Z et al.	—	2024	→
Optimizing clinico-genomic disease prediction across ancestries: a machine learning strategy with Pareto improvement.	Gao Y et al.	—	2024	→
Parkinson Disease Genetics Extended to African and Hispanic Ancestries in the VA Million Veteran Program.	Pankratz N et al.	—	2024	→
PGS-Depot: a comprehensive resource for polygenic scores constructed by summary statistics based methods.	Cao C et al.	—	2024	→
Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder.	Nuñez NA et al.	—	2024	→
Pharmacogenomics Beyond Single Common Genetic Variants: The Way Forward.	Lauschke VM et al.	—	2024	→
Polygenic embryo screening: quo vadis?	Siermann M et al.	—	2024	→
Polygenic prediction for underrepresented populations through transfer learning by utilizing genetic similarity shared with European populations.	Zhu Y et al.	—	2024	→
Polygenic Prediction of Keratoconus and its Measures: Cross-Sectional and Longitudinal Analyses in Community-Based Young Adults.	Lee SS et al.	—	2024	→
Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder.	LaBianca S et al.	—	2024	→
Polygenic risk for Alzheimer's disease is associated with neuroaxonal damage before onset of clinical symptoms.	Kagerer SM et al.	—	2024	→
Polygenic risk of social isolation behavior and its influence on psychopathology and personality.	Socrates AJ et al.	—	2024	→
Polygenic Risk Score, Cardiorespiratory Fitness, and Cardiometabolic Risk Factors: WASEDA'S Health Study.	Tanisawa K et al.	—	2024	→
Polygenic Risk Score Implementation into Clinical Practice for Primary Prevention of Cardiometabolic Disease.	Hughes J et al.	—	2024	→
Polygenic Risk Score Improves Melanoma Risk Assessment in a Patient Cohort from the Veneto Region of Italy.	Pellegrini S et al.	—	2024	→
Polygenic risk score model for renal cell carcinoma in the Korean population and relationship with lifestyle-associated factors.	Hong JY et al.	—	2024	→
Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese.	Hung SC et al.	—	2024	→
Polygenic Risk Scores and Hearing Loss Phenotypes in Children.	Wang J et al.	—	2024	→
Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events.	Heyne HO et al.	—	2024	→
Polygenic risk scores for cardiovascular risk prediction: moving towards implementation into clinical practice?	Christoffersen M et al.	—	2024	→
Polygenic risk scores, radiation treatment exposures and subsequent cancer risk in childhood cancer survivors.	Gibson TM et al.	—	2024	→
Polygenic Risk Scores: The Next Step for Improved Risk Stratification in Coronary Artery Disease?	Stein R et al.	—	2024	→
Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.	Yiangou K et al.	—	2024	→
Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study.	Mandla R et al.	—	2024	→
Polygenic scores for tobacco use provide insights into systemic health risks in a diverse EHR-linked biobank in Los Angeles.	Venkateswaran V et al.	—	2024	→
Population Heterogeneity and Selection of Coronary Artery Disease Polygenic Scores.	Debernardi C et al.	—	2024	→
Precision medicine in cardiovascular therapeutics: Evaluating the role of pharmacogenetic analysis prior to drug treatment.	Ingelman-Sundberg M et al.	—	2024	→
Predicting ADHD in alcohol dependence using polygenic risk scores for ADHD.	Patel KHS et al.	—	2024	→
Predicting Survival Among Colorectal Cancer Patients: Development and Validation of Polygenic Survival Score.	Maawadh RM et al.	—	2024	→
Principles and methods for transferring polygenic risk scores across global populations.	Kachuri L et al.	—	2024	→
Prognosis prediction and risk stratification of breast cancer patients based on a mitochondria-related gene signature.	Wang Y et al.	—	2024	→
Prognostic mutation signature would serve as a potential prognostic predictor in patients with diffuse large B-cell lymphoma.	Cho SF et al.	—	2024	→
Promises and Challenges of populational Proteomics in Health and Disease.	Sun BB et al.	—	2024	→
Psychiatric neuroimaging at a crossroads: Insights from psychiatric genetics.	Dall'Aglio L et al.	—	2024	→
Psychiatric Polygenic Risk Scores Across Youth With Bipolar Disorder, Youth at High Risk for Bipolar Disorder, and Controls.	Jiang X et al.	—	2024	→
Race, ethnicity, ancestry, and aspects that impact HLA data and matching for transplant.	Madbouly A et al.	—	2024	→
Recent advances in polygenic scores: translation, equitability, methods and FAIR tools.	Xiang R et al.	—	2024	→
Relationship between Polygenic Risk Score and the Hypnotics in Bipolar I Disorder.	Lee HW et al.	—	2024	→
Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk.	Kim Y et al.	—	2024	→
Review of pharmacogenetics of antiseizure medications: focusing on genetic variants of mechanistic targets.	Lin CH et al.	—	2024	→
Risk Assessment for Gastrointestinal Diseases via Clinical Dimension and Genome-Wide Polygenic Risk Scores of Type 2 Diabetes: A Population-Based Cohort Study.	Fu T et al.	—	2024	→
Role of Genetic Testing in Kidney Stone Disease: A Narrative Review.	Geraghty R et al.	—	2024	→
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.	Lennon NJ et al.	—	2024	→
Shared familial risk for type 2 diabetes mellitus and psychiatric disorders: a nationwide multigenerational genetics study.	Wimberley T et al.	—	2024	→
Stacked neural network for predicting polygenic risk score.	Kim SB et al.	—	2024	→
Subset scanning for multi-trait analysis using GWAS summary statistics.	Cao R et al.	—	2024	→
Taking the risk. A systematic review of ethical reasons and moral arguments in the clinical use of polygenic risk scores.	Andreoli L et al.	—	2024	→
Teaching gene-environment interaction concepts with narrative vignettes: Effects on knowledge, stigma, and behavior motivation.	Chen J et al.	—	2024	→
The effect of polygenic risk score and childhood adversity on transdiagnostic symptom dimensions at first-episode psychosis: evidence for an affective pathway to psychosis.	Alameda L et al.	—	2024	→
The expanding field of genetic developmental and epileptic encephalopathies: current understanding and future perspectives.	Specchio N et al.	—	2024	→
The genetic landscape of substance use disorders.	Gerring ZF et al.	—	2024	→
The Inclusion of Underrepresented Populations in Cardiovascular Genetics and Epidemiology.	Chappell E et al.	—	2024	→
The researcher's guide to selecting biomarkers in mental health studies.	Verhoeven JE et al.	—	2024	→
The Role of Genetics in Managing Peripheral Arterial Disease.	Biagetti G et al.	—	2024	→
The utility of obesity polygenic risk scores from research to clinical practice: A review.	Jansen PR et al.	—	2024	→
Toward Realizing the Promise of AI in Precision Health Across the Spectrum of Care.	Wiens J et al.	—	2024	→
Towards Personalized Medicine in Rheumatoid Arthritis.	Sharma SD et al.	—	2024	→
Translational Research on Polygenic Risk Scores in Common Neurodegenerative Diseases - A Scoping Review Protocol.	Čižek Sajko M et al.	—	2024	→
Understanding the Genetic Architecture of Vitamin Status Biomarkers in the Genome-Wide Association Study Era: Biological Insights and Clinical Significance.	Reay WR et al.	—	2024	→
Unraveling the multifaceted insights into amyotrophic lateral sclerosis: Genetic underpinnings, pathogenesis, and therapeutic horizons.	Sharma R et al.	—	2024	→
Using Genetics to Inform Interventions Related to Sodium and Potassium in Hypertension.	Reay WR et al.	—	2024	→
Using Omics to Identify Novel Therapeutic Targets in Heart Failure.	Lteif C et al.	—	2024	→
Using Polygenic Risk Scores to Aid Diagnosis of Patients With Early Inflammatory Arthritis: Results From the Norfolk Arthritis Register.	Hum RM et al.	—	2024	→
Using polygenic scores in combination with symptom rating scales to identify attention-deficit/hyperactivity disorder.	Høberg A et al.	—	2024	→
Using the Strategy of Genome-Wide Association Studies to Identify Genetic Markers of Suicidal Behavior: A Narrative Review.	Rozanov V et al.	—	2024	→
Utility of polygenic scores across diverse diseases in a hospital cohort for predictive modeling.	Sun TH et al.	—	2024	→
Validation of a polygenic risk score for frailty in the Lothian Birth Cohort 1936 and English longitudinal study of ageing.	Flint JP et al.	—	2024	→
Validity of European-centric cardiometabolic polygenic scores in multi-ancestry populations.	Topriceanu CC et al.	—	2024	→
Variability in performance of genetic-enhanced DXA-BMD prediction models across diverse ethnic and geographic populations: A risk prediction study.	Liu Y et al.	—	2024	→
Vitamin D status and variable responses to supplements depend in part on genetic factors in adults with cystic fibrosis.	Braun AT et al.	—	2024	→
Weighty matters: Considering the ethics of genetic risk scores for obesity.	Houtz C	—	2024	→
Whole genome sequencing in clinical practice.	Bagger FO et al.	—	2024	→
Abdominal obesity is a more important causal risk factor for pancreatic cancer than overall obesity.	Maina JG et al.	—	2023	→
Addressing the Challenge of Biomedical Data Inequality: An Artificial Intelligence Perspective.	Gao Y et al.	—	2023	→
Adherence to a healthy lifestyle, genetic susceptibility to abdominal obesity, cardiometabolic risk markers, and risk of coronary heart disease.	Wang M et al.	—	2023	→
Advancing the communication of genetic risk for cardiometabolic diseases: a critical interpretive synthesis.	Law JH et al.	—	2023	→
A flexible empirical Bayes approach to multivariate multiple regression, and its improved accuracy in predicting multi-tissue gene expression from genotypes.	Morgante F et al.	—	2023	→
A genome-wide association, polygenic risk score and sex study on opioid use disorder treatment outcomes.	McEvoy A et al.	—	2023	→
AI-based multi-PRS models outperform classical single-PRS models.	Klau JH et al.	—	2023	→
A multilocus genetic risk score for obesity: Association with BMI and metabolic alterations in a cohort with severe obesity.	Sag SJM et al.	—	2023	→
Analysis of ancestry-specific polygenic risk score and diet composition in type 2 diabetes.	Hardy DS et al.	—	2023	→
A narrative review of precision medicine in neonatal sepsis: genetic and epigenetic factors associated with disease susceptibility.	Dai W et al.	—	2023	→
An interpretable Alzheimer's disease oligogenic risk score informed by neuroimaging biomarkers improves risk prediction and stratification.	Suh EH et al.	—	2023	→
A novel integrative multi-omics approach to unravel the genetic determinants of rare diseases with application in sinusoidal obstruction syndrome.	Waespe N et al.	—	2023	→
A Pharmaceutical Paradigm for Cardiovascular Composite Risk Assessment Using Novel Radiogenomics Risk Predictors in Precision Explainable Artificial Intelligence Framework: Clinical Trial Tool.	Saba L et al.	—	2023	→
A polygenic risk score to help discriminate primary adrenal insufficiency of different etiologies.	Aranda-Guillén M et al.	—	2023	→
A Social and Ethical Framework for Providing Health Information Obtained from Combining Genetics and Fitness Tracking Data.	Esmonde K et al.	—	2023	→
Assessment of cardiovascular disease risk: a 2023 update.	Goldsborough E et al.	—	2023	→
Assisted reproductive technologies at the nexus of fertility treatment and disease prevention.	Herbert M et al.	—	2023	→
Association between inflammatory bowel disease and Parkinson's disease: a prospective cohort study of 468,556 UK biobank participants.	Wang HL et al.	—	2023	→
Association of genetic risk and lifestyle with incident adult-onset asthma in the UK Biobank cohort.	Liang H et al.	—	2023	→
Association of Polygenic Risk Scores for Hearing Difficulty in Older Adults With Hearing Loss in Mid-Childhood and Midlife: A Population-Based Cross-sectional Study Within the Longitudinal Study of Australian Children.	Wang J et al.	—	2023	→
Associations between polygenic risk score and covid-19 susceptibility and severity across ethnic groups: UK Biobank analysis.	Farooqi R et al.	—	2023	→
Associations between the Genetic Heritability of Dyslipidemia and Dietary Patterns in Korean Adults Based on Sex Differences.	Kim S et al.	—	2023	→
A Systematic Review and Critical Assessment of Breast Cancer Risk Prediction Tools Incorporating a Polygenic Risk Score for the General Population.	Mbuya-Bienge C et al.	—	2023	→
A Systematic Review of the Biological Correlates and Consequences of Childhood Maltreatment and Adverse Childhood Experiences.	Cooke EM et al.	—	2023	→
Atopic Polygenic Risk Score Is Associated with Paradoxical Eczema Developing in Patients with Psoriasis Treated with Biologics.	Al-Janabi A et al.	—	2023	→
Australian parental perceptions of genomic newborn screening for non-communicable diseases.	Casauria S et al.	—	2023	→
Avoiding Liability and Other Legal Land Mines in the Evolving Genomics Landscape.	Clayton EW et al.	—	2023	→
Bacterial Community Modifies Host Genetics Effect on Early Childhood Caries.	Blostein F et al.	—	2023	→
Biobank-scale methods and projections for sparse polygenic prediction from machine learning.	Raben TG et al.	—	2023	→
Characterizing the polygenic architecture of complex traits in populations of East Asian and European descent.	De Lillo A et al.	—	2023	→
Childhood trajectories of internalising and externalising problems associated with a polygenic risk score for neuroticism in a UK birth cohort study.	Costantini I et al.	—	2023	→
Clinical utility of polygenic risk scores: a critical 2023 appraisal.	Koch S et al.	—	2023	→
Cluster headache polygenetic risk and known functional variants of CYP3A4 are not associated with treatment response.	Petersen AS et al.	—	2023	→
Combating hypertension beyond genome-wide association studies: Microbiome and artificial intelligence as opportunities for precision medicine.	Aryal S et al.	—	2023	→
Co-occurrence of chronic kidney disease and glaucoma: Epidemiology and etiological mechanisms.	Liu W et al.	—	2023	→
Coronary heart disease and ischemic stroke polygenic risk scores and atherosclerotic cardiovascular disease in a diverse, population-based cohort study.	Bebo A et al.	—	2023	→
Could interventions on physical activity mitigate genomic liability for obesity? Applying the health disparity framework in genetically informed studies.	Herle M et al.	—	2023	→
Creation of a structured molecular genomics report for Germany as a local adaption of HL7's Genomic Reporting Implementation Guide.	Stellmach C et al.	—	2023	→
Cross-National and Cross-Generational Evidence That Educational Attainment May Slow the Pace of Aging in European-Descent Individuals.	Sugden K et al.	—	2023	→
Current Evidence for Biological Biomarkers and Mechanisms Underlying Acute to Chronic Pain Transition across the Pediatric Age Spectrum.	Duff IT et al.	—	2023	→
Current State and Future of Polygenic Risk Scores in Cardiometabolic Disease: A Scoping Review.	Phulka JS et al.	—	2023	→
Data-driven subgroups of newly diagnosed type 2 diabetes and the relationship with cardiovascular diseases at genetic and clinical levels in Chinese adults.	Wang W et al.	—	2023	→
DeepGAMI: deep biologically guided auxiliary learning for multimodal integration and imputation to improve genotype-phenotype prediction.	Chandrashekar PB et al.	—	2023	→
Deep integrative models for large-scale human genomics.	Sigurdsson AI et al.	—	2023	→
Depression Trajectories, Genetic Risk, and Cognitive Performance in Older Adults: Multilevel Model with a 10-Year Longitudinal Cohort.	Liu Z et al.	—	2023	→
Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back Pain.	Tsepilov YA et al.	—	2023	→
Development and Validation of Risk Prediction Models for Colorectal Cancer in Patients with Symptoms.	Xu W et al.	—	2023	→
Development of risk prediction models for depression combining genetic and early life risk factors.	Lu T et al.	—	2023	→
Differential Effects of ADHD Polygenic Risk on Cognitive Performance in Later Life.	Mansoor M et al.	—	2023	→
Disentangling the complexity of psoriasis in the post-genome-wide association era.	Antonatos C et al.	—	2023	→
Does polygenic risk for substance-related traits predict ages of onset and progression of symptoms?	Kranzler HR et al.	—	2023	→
Double Mutations in a Patient with Early-Onset Alzheimer's Disease in Korea: An <i>APP</i> Val551Met and a <i>PSEN2</i> His169Asn.	Bae H et al.	—	2023	→
Effects of gene-lifestyle interactions on obesity based on a multi-locus risk score: A cross-sectional analysis.	Nakamura S et al.	—	2023	→
Ethical layering in AI-driven polygenic risk scores-New complexities, new challenges.	Fritzsche MC et al.	—	2023	→
Ethical, legal, and social implications of genetic risk prediction for multifactorial disease: a narrative review identifying concerns about interpretation and use of polygenic scores.	Chapman CR	—	2023	→
Ethnic disparities in fracture risk assessment using polygenic scores.	Xiao X et al.	—	2023	→
Evaluation of polygenic risk score for risk prediction of gastric cancer.	Wang XY et al.	—	2023	→
Expanding the application of haplotype-based genomic predictions to the wild: A case of antibody response against Teladorsagia circumcincta in Soay sheep.	Vahedi SM et al.	—	2023	→
Factors associated with anxiety disorder comorbidity.	Davies MR et al.	—	2023	→
Fast and accurate Bayesian polygenic risk modeling with variational inference.	Zabad S et al.	—	2023	→
Founder population-specific weights yield improvements in performance of polygenic risk scores for Alzheimer disease in the Midwestern Amish.	Osterman MD et al.	—	2023	→
Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults.	Wang X et al.	—	2023	→
Generalisation of genomic findings and applications of polygenic risk scores.	Corpas M et al.	—	2023	→
Gene Teams are on the Field: Evaluation of Variants in Gene-Networks Using High Dimensional Modelling.	Tuna S et al.	—	2023	→
Genetic and Epigenetic Mechanisms of Psoriasis.	Mateu-Arrom L et al.	—	2023	→
Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders.	David FS et al.	—	2023	→
Genetic counseling for pre-implantation genetic testing of monogenic disorders (PGT-M).	Parikh F et al.	—	2023	→
Genetic Evaluation and Screening in Cardiomyopathies: Opportunities and Challenges for Personalized Medicine.	Aiyer S et al.	—	2023	→
Genetic Inheritance Models of Non-Syndromic Cleft Lip with or without Palate: From Monogenic to Polygenic.	Cheng X et al.	—	2023	→
Genetic landscape of Parkinson's disease and related diseases in Luxembourg.	Landoulsi Z et al.	—	2023	→
Genetic Risk Assessment of Nonsyndromic Cleft Lip with or without Cleft Palate by Linking Genetic Networks and Deep Learning Models.	Kang G et al.	—	2023	→
Genetic risk, muscle strength and risk of incident major depressive disorder: results from the UK Biobank.	Gu Y et al.	—	2023	→
Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity.	Bakker MK et al.	—	2023	→
Genetic Risk Score Improves Risk Stratification for Anticoagulation-Related Intracerebral Hemorrhage.	Mayerhofer E et al.	—	2023	→
Genetic risk score in multiple sclerosis is associated with unique gut microbiome.	Elsayed NS et al.	—	2023	→
Genetic risk score is associated with T2DM and diabetes complications risks.	Hubacek JA et al.	—	2023	→
Genetic Risk Scores and Missing Heritability in Ovarian Cancer.	Fatapour Y et al.	—	2023	→
Genetic Risk Scores for the Determination of Type 2 Diabetes Mellitus (T2DM) in North India.	Shitomi-Jones LM et al.	—	2023	→
Genetics and epigenetics of stress: New avenues for an old concept.	Soliva-Estruch M et al.	—	2023	→
Genetics: A Starting Point for the Prevention and the Treatment of Obesity.	Novelli G et al.	—	2023	→
Genetics of cannabis use in opioid use disorder: A genome-wide association and polygenic risk score study.	Hillmer A et al.	—	2023	→
Genetic variants for smoking behaviour and risk of skin cancer.	Dusingize JC et al.	—	2023	→
Genome-wide association studies of cardiovascular disease.	Walsh R et al.	—	2023	→
Genomic Stratification of Clozapine Prescription Patterns Using Schizophrenia Polygenic Scores.	Kappel DB et al.	—	2023	→
Getting the Most Out of Your Genome-Wide Association Study Using Polygenic Risk Scores.	Maggioncalda E et al.	—	2023	→
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts.	Wang Y et al.	—	2023	→
Harnessing the potential of machine learning and artificial intelligence for dementia research.	Ranson JM et al.	—	2023	→
Height-Related Polygenic Variants Are Associated with Metabolic Syndrome Risk and Interact with Energy Intake and a Rice-Main Diet to Influence Height in KoGES.	Park S	—	2023	→
Heuristic Approach Uncovering Biological Significance of Gene-Lifestyle Interactions in Cardiometabolic Traits.	San-Cristobal R et al.	—	2023	→
Human Genetics Society of Australasia Position Statement: Use of Polygenic Scores in Clinical Practice and Population Health.	Young MA et al.	—	2023	→
Human height: a model common complex trait.	Conery M et al.	—	2023	→
Impact of intrinsic and extrinsic risk factors on early-onset lung disease in cystic fibrosis.	Huang L et al.	—	2023	→
Implementation and evaluation of personal genetic testing as part of genomics analysis courses in German universities.	Slosarek T et al.	—	2023	→
Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female-Specific Health Conditions.	Xiao B et al.	—	2023	→
Integrating Common Risk Factors with Polygenic Scores Improves the Prediction of Type 2 Diabetes.	Timasheva Y et al.	—	2023	→
Integrating Theory with Education about Genetic Risk for Alcohol Use Disorder: The Effects of a Brief Online Educational Tool on Elements of the Health Belief Model.	Driver MN et al.	—	2023	→
Integration of a Cross-Ancestry Polygenic Model With Clinical Risk Factors Improves Breast Cancer Risk Stratification.	Tshiaba PT et al.	—	2023	→
Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia.	Radulescu E et al.	—	2023	→
Investigation of heteroscedasticity in polygenic risk scores across 15 quantitative traits.	Jung H et al.	—	2023	→
Let's Not Repeat History's Mistakes: Two Cautions to Scientists on the Use of Race in Alzheimer's Disease and Alzheimer's Disease Related Dementias Research.	Stites SD et al.	—	2023	→
Limitations, concerns and potential: attitudes of healthcare professionals toward preimplantation genetic testing using polygenic risk scores.	Siermann M et al.	—	2023	→
Machine learning and phylogenetic analysis allow for predicting antibiotic resistance in M. tuberculosis.	Yurtseven A et al.	—	2023	→
Machine Learning to Advance Human Genome-Wide Association Studies.	Sigala RE et al.	—	2023	→
Maternal depression and the polygenic p factor: A family perspective on direct and indirect effects.	Ayorech Z et al.	—	2023	→
Melanoma risk prediction based on a polygenic risk score and clinical risk factors.	Wong CK et al.	—	2023	→
Mode of transport, genetic susceptibility, and incidence of coronary heart disease.	Jiesisibieke ZL et al.	—	2023	→
mtPGS: Leverage multiple correlated traits for accurate polygenic score construction.	Xu C et al.	—	2023	→
Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus.	Khunsriraksakul C et al.	—	2023	→
Multi-system diseases and death trajectory of metabolic dysfunction-associated fatty liver disease: findings from the UK Biobank.	Jia Y et al.	—	2023	→
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications.	Andreassen OA et al.	—	2023	→
New Research Perspectives on the Interplay Between Genes and Environment on Executive Function Development.	Miguel PM et al.	—	2023	→
Novel Polygenic Risk Score for Intracranial Aneurysms.	Frerich S et al.	—	2023	→
Pan-cancer proteogenomics connects oncogenic drivers to functional states.	Li Y et al.	—	2023	→
Perceived benefits and barriers to implementing precision preventive care: Results of a national physician survey.	Vassy JL et al.	—	2023	→
Polygenic risk of type 2 diabetes is associated with incident vascular dementia: a prospective cohort study.	Dybjer E et al.	—	2023	→
Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions.	Fatumo S et al.	—	2023	→
Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study.	Ho PJ et al.	—	2023	→
Polygenic risk scores in pharmacogenomics: opportunities and challenges-a mini review.	Simona A et al.	—	2023	→
Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents.	Zwicker A et al.	—	2023	→
Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly - comparative results from the KORA and AugUR study.	Herold JM et al.	—	2023	→
Polygenic Scores in the Direct-to-Consumer Setting: Challenges and Opportunities for a New Era in Consumer Genetic Testing.	Park JK et al.	—	2023	→
Polygenic Susceptibility to Hypertension and Cognitive Performance in Middle-aged Persons Without Stroke or Dementia.	Rivier CA et al.	—	2023	→
Polygenic Variants Linked to Oxidative Stress and the Antioxidant System Are Associated with Type 2 Diabetes Risk and Interact with Lifestyle Factors.	Choi Y et al.	—	2023	→
Power of inclusion: Enhancing polygenic prediction with admixed individuals.	Tanigawa Y et al.	—	2023	→
Precision Nutrition: Recent Advances in Obesity.	Voruganti VS	—	2023	→
Primary care physician use of patient race and polygenic risk scores in medical decision-making.	Kerman BJ et al.	—	2023	→
Prognostic evaluation of polygenic risk score underlying pan-cancer analysis: evidence from two large-scale cohorts.	Xin J et al.	—	2023	→
Quantifying portable genetic effects and improving cross-ancestry genetic prediction with GWAS summary statistics.	Miao J et al.	—	2023	→
Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort.	Akhtari FS et al.	—	2023	→
Relationship of Family Genetic Risk Score With Diagnostic Trajectory in a Swedish National Sample of Incident Cases of Major Depression, Bipolar Disorder, Other Nonaffective Psychosis, and Schizophrenia.	Kendler KS et al.	—	2023	→
Research progress and challenges of preimplantation genetic testing for polygenic diseases.	Wu X et al.	—	2023	→
Response to anti-IL17 therapy in inflammatory disease is not strongly impacted by genetic background.	Zhang C et al.	—	2023	→
Risk assessment for colorectal cancer via polygenic risk score and lifestyle exposure: a large-scale association study of East Asian and European populations.	Xin J et al.	—	2023	→
Risk prediction of nephropathy by integrating clinical and genetic information among adult patients with type 2 diabetes.	Liao LN et al.	—	2023	→
Robust Bioinformatics Approaches Result in the First Polygenic Risk Score for BMI in Greek Adults.	Kafyra M et al.	—	2023	→
Role of IL-17A in different stages of ischemic stroke.	Chen X et al.	—	2023	→
Schizophrenia polygenic risk score in psychosis proneness.	Mas-Bermejo P et al.	—	2023	→
Screening for Coronary Artery Disease in Cancer Survivors: <i>JACC: CardioOncology</i> State-of-the-Art Review.	Velusamy R et al.	—	2023	→
Semantic and Population Analysis of the Genetic Targets Related to COVID-19 and Its Association with Genes and Diseases.	Papageorgiou L et al.	—	2023	→
Sex differences in the genetic and molecular mechanisms of coronary artery disease.	Sakkers TR et al.	—	2023	→
Shared Genetic Risk in the Association of Screen Time With Psychiatric Problems in Children.	Zhang Y et al.	—	2023	→
Sibling variation in polygenic traits and DNA recombination mapping with UK Biobank and IVF family data.	Lello L et al.	—	2023	→
Significance tests for R<sup>2</sup> of out-of-sample prediction using polygenic scores.	Momin MM et al.	—	2023	→
Stakeholder Perception of the Implementation of Genetic Risk Testing for Twelve Multifactorial Diseases.	Tokutomi T et al.	—	2023	→
Step by step: towards a better understanding of the genetic architecture of Alzheimer's disease.	Lambert JC et al.	—	2023	→
Strategies for the Genomic Analysis of Admixed Populations.	Tan T et al.	—	2023	→
Sub-types of insomnia in adolescents: Insights from a quantitative/molecular twin study.	Madrid-Valero JJ et al.	—	2023	→
Testing a Polygenic Risk Score for Morphological Microglial Activation in Alzheimer's Disease and Aging.	Tio ES et al.	—	2023	→
The Applicability of Polygenic Risk Scores in Under-Represented Populations.	Riefski K et al.	—	2023	→
The Application of Genetic Risk Scores in Rheumatic Diseases: A Perspective.	Vaskimo LM et al.	—	2023	→
The association between polygenic risk scores for mental disorders and social cognition: A scoping review.	Fusar-Poli L et al.	—	2023	→
The clinical utility of the BMD-related comprehensive genome-wide polygenic score in identifying individuals with a high risk of osteoporotic fractures.	Xiao X et al.	—	2023	→
The complementary roles of genome-wide approaches in identifying genes linked to an inherited risk of colorectal cancer.	Ahmad O et al.	—	2023	→
The foundation and architecture of precision medicine in neurology and psychiatry.	Hampel H et al.	—	2023	→
The genetic architecture of schizophrenia: review of large-scale genetic studies.	Kato H et al.	—	2023	→
The GenoVA study: Equitable implementation of a pragmatic randomized trial of polygenic-risk scoring in primary care.	Vassy JL et al.	—	2023	→
The interplay of family history of depression and early trauma: associations with lifetime and current depression in the German national cohort (NAKO).	Streit F et al.	—	2023	→
The multifactorial nature of healthy brain ageing: Brain changes, functional decline and protective factors.	Turrini S et al.	—	2023	→
The Non-Invasive Assessment of Circulating D-Loop and mt-ccf Levels Opens an Intriguing Spyhole into Novel Approaches for the Tricky Diagnosis of NASH.	Paolini E et al.	—	2023	→
The PANcreatic Disease ReseArch (PANDoRA) consortium: Ten years' experience of association studies to understand the genetic architecture of pancreatic cancer.	Campa D et al.	—	2023	→
The role of polygenic risk scores in breast cancer risk perception and decision-making.	Riddle L et al.	—	2023	→
Transforming global approaches to chronic disease prevention and management across the lifespan: integrating genomics, behavior change, and digital health solutions.	Thomas SA et al.	—	2023	→
Treatment-Resistant Schizophrenia, Clozapine Resistance, Genetic Associations, and Implications for Precision Psychiatry: A Scoping Review.	Ying J et al.	—	2023	→
Triangulating nutrigenomics, metabolomics and microbiomics toward personalized nutrition and healthy living.	Lagoumintzis G et al.	—	2023	→
UK biobank: Enhanced assessment of the epidemiology and long-term impact of coronavirus disease-2019.	Feng Q et al.	—	2023	→
Validation of lung cancer polygenic risk scores in a high-risk case-control cohort.	Lebrett MB et al.	—	2023	→
Variant-based heritability assessment of dexmedetomidine and fentanyl clearance in pediatric patients.	Shannon ML et al.	—	2023	→
Variation and impact of polygenic hematologic traits in monogenic sickle cell disease.	Pincez T et al.	—	2023	→
Weight Loss Is a Strong Predictor of Memory Disorder Independent of Genetic Influences.	Chen S et al.	—	2023	→
A comprehensive evaluation of polygenic score and genotype imputation performances of human SNP arrays in diverse populations.	Nguyen DT et al.	—	2022	→
A Gene-Environment Interaction Study of Polygenic Scores and Maltreatment on Childhood ADHD.	He Q et al.	—	2022	→
Alzheimer's Disease Polygenic Risk Score Is Not Associated With Cognitive Decline Among Older Adults With Type 2 Diabetes.	Manzali SB et al.	—	2022	→
Aortic Pulse Wave Velocity as Adjunct Risk Marker for Assessing Cardiovascular Disease Risk: Prospective Study.	Valencia-Hernández CA et al.	—	2022	→
A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam.	Campbell C et al.	—	2022	→
Apolipoprotein L1 variability is associated with increased risk of renal failure in the Czech population.	Hubacek JA et al.	—	2022	→
A Polygenic Approach to Understanding Resilience to Peer Victimisation.	Armitage JM et al.	—	2022	→
Application of hyperglycemia/diabetes-derived polygenic risk scores on the risk of poor outcomes after an ischemic stroke.	Chen YL et al.	—	2022	→
Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank.	Green HD et al.	—	2022	→
Appraisal of Gene-Environment Interactions in GWAS for Evidence-Based Precision Nutrition Implementation.	San-Cristobal R et al.	—	2022	→
Artificial intelligence and machine learning approaches using gene expression and variant data for personalized medicine.	Vadapalli S et al.	—	2022	→
Assessing agreement between different polygenic risk scores in the UK Biobank.	Clifton L et al.	—	2022	→
Assessing the effect of interaction between gut microbiome and inflammatory bowel disease on the risks of depression.	Qin X et al.	—	2022	→
Assessment of Cardiovascular Disease Risk: A 2022 Update.	Goldsborough E et al.	—	2022	→
Association of polygenic risk for schizophrenia with fast sleep spindle density depends on pro-cognitive variants.	Schilling C et al.	—	2022	→
Association of polygenic risk scores and hair cortisol with mental health trajectories during COVID lockdown.	Ahrens KF et al.	—	2022	→
Association of Polygenic Variants with Type 2 Diabetes Risk and Their Interaction with Lifestyles in Asians.	Hur HJ et al.	—	2022	→
Associations of combined lifestyle and genetic risks with incident psoriasis: A prospective cohort study among UK Biobank participants of European ancestry.	Shen M et al.	—	2022	→
Associations of genetic susceptibility and healthy lifestyle with incidence of coronary heart disease and stroke in individuals with hypertension.	Wang M et al.	—	2022	→
A Systematic Review and Analysis of the Use of Polygenic Scores in Pharmacogenomics.	Johnson D et al.	—	2022	→
A tool for translating polygenic scores onto the absolute scale using summary statistics.	Pain O et al.	—	2022	→
Calculating Polygenic Risk Scores (PRS) in UK Biobank: A Practical Guide for Epidemiologists.	Collister JA et al.	—	2022	→
Can polygenic risk scores contribute to cost-effective cancer screening? A systematic review.	Dixon P et al.	—	2022	→
Cardiovascular Genetics: The Role of Genetics in Predicting Risk.	Chowns J et al.	—	2022	→
Challenges and Opportunities for Developing More Generalizable Polygenic Risk Scores.	Wang Y et al.	—	2022	→
Clinical genomics and precision medicine.	Pena SDJ et al.	—	2022	→
Coming of Age: Human Genomics and the Cancer-Immune Set Point.	Hammer C et al.	—	2022	→
Comparing personalized brain-based and genetic risk scores for major depressive disorder in large population samples of adults and adolescents.	Thng G et al.	—	2022	→
Comparison of Methods Utilizing Sex-Specific PRSs Derived From GWAS Summary Statistics.	Zhang C et al.	—	2022	→
Constructing an atlas of associations between polygenic scores from across the human phenome and circulating metabolic biomarkers.	Fang S et al.	—	2022	→
Cost-Effectiveness of Polygenic Risk Scores to Guide Statin Therapy for Cardiovascular Disease Prevention.	Kiflen M et al.	—	2022	→
Defining the extent of gene function using ROC curvature.	Fischer S et al.	—	2022	→
Depressive symptom trajectories and polygenic risk scores in individuals with an immune-mediated inflammatory disease.	Kowalec K et al.	—	2022	→
Developmental Language Disorder and Psychopathology: Disentangling Shared Genetic and Environmental Influences.	Toseeb U et al.	—	2022	→
Development and validation of a polygenic hazard score to predict prognosis and adjuvant chemotherapy benefit in early-stage non-small cell lung cancer.	Li DH et al.	—	2022	→
Development of a clinical polygenic risk score assay and reporting workflow.	Hao L et al.	—	2022	→
Does APOE ɛ4 Status Change How 24-Hour Time-Use Composition Is Associated with Cognitive Function? An Exploratory Analysis Among Middle-to-Older Adults.	Dumuid D et al.	—	2022	→
Editorial: Does the polygenic revolution herald a watershed in the study of GE interplay in developmental psychopathology? Some considerations for the Special Issue reader.	Barker ED et al.	—	2022	→
Educational considerations based on medical student use of polygenic risk information and apparent race in a simulated consultation.	Hollister BM et al.	—	2022	→
Ethnic Diversity and Warfarin Pharmacogenomics.	Asiimwe IG et al.	—	2022	→
Etiologic Puzzle of Coronary Artery Disease: How Important Is Genetic Component?	Butnariu LI et al.	—	2022	→
From the prodromal stage of multiple sclerosis to disease prevention.	Marrie RA et al.	—	2022	→
Functional genomics of complex cancer genomes.	Menghi F et al.	—	2022	→
Gene-Environment Correlation over Time: A Longitudinal Analysis of Polygenic Risk Scores for Schizophrenia and Major Depression in Three British Cohorts Studies.	Machlitt-Northen S et al.	—	2022	→
Generalization of cortical MOSTest genome-wide associations within and across samples.	Loughnan RJ et al.	—	2022	→
Genetically determined gut microbial abundance and 2-year changes in central adiposity and body composition: The POUNDS lost trial.	Li X et al.	—	2022	→
Genetic and environmental variation impact transferability of polygenic risk scores.	Araújo DS et al.	—	2022	→
Genetic and Social-Environmental Influences on Posttraumatic Stress Disorder.	Lawn RB	—	2022	→
Genetic Association of Attention-Deficit/Hyperactivity Disorder and Major Depression With Suicidal Ideation and Attempts in Children: The Adolescent Brain Cognitive Development Study.	Lee PH et al.	—	2022	→
Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL.	Zhang Y et al.	—	2022	→
Genetic determinants of polygenic prediction accuracy within a population.	Lu T et al.	—	2022	→
Genetic factors help explain the variable responses of young children with cystic fibrosis to vitamin D supplements.	Lai HJ et al.	—	2022	→
Genetic Modifiers of Sickle Cell Disease.	Pincez T et al.	—	2022	→
Genetic Risk Factors and Gene-Lifestyle Interactions in Gestational Diabetes.	Jääskeläinen T et al.	—	2022	→
Genetic risk factors have a substantial impact on healthy life years.	Jukarainen S et al.	—	2022	→
Genetic Risk for Osteoporosis and the Benefit of Adherence to Healthy Lifestyles.	Yang YQ et al.	—	2022	→
Genetic Risk Score Enhances Coronary Artery Disease Risk Prediction in Individuals With Type 1 Diabetes.	Lithovius R et al.	—	2022	→
Genetics in parkinson's disease: From better disease understanding to machine learning based precision medicine.	Aborageh M et al.	—	2022	→
Genetic susceptibility, screen-based sedentary activities and incidence of coronary heart disease.	Kim Y et al.	—	2022	→
Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank.	Gouveia C et al.	—	2022	→
Genome-wide association study-based prediction of atrial fibrillation using artificial intelligence.	Kwon OS et al.	—	2022	→
Genome-Wide Association Study of Clinical Outcome After Aneurysmal Subarachnoid Haemorrhage: Protocol.	Gaastra B et al.	—	2022	→
Genome-Wide Gene-Set Analysis Approaches in Amyotrophic Lateral Sclerosis.	Vasilopoulou C et al.	—	2022	→
Genome-wide polygenic risk impact on intracranial aneurysms and acute ischemic stroke.	Hong EP et al.	—	2022	→
Genomic architecture of autism from comprehensive whole-genome sequence annotation.	Trost B et al.	—	2022	→
Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse-Brief Report.	Richardson TG et al.	—	2022	→
Hereditary Breast and Ovarian Cancer: An Updated Primer for OB/GYNs.	Bellcross CA	—	2022	→
How can we address the uncertainties regarding the potential clinical utility of polygenic score-based tests?	Moorthie S et al.	—	2022	→
How does genetic variation modify ND-CNV phenotypes?	Dinneen TJ et al.	—	2022	→
How to proceed after "negative" exome: A review on genetic diagnostics, limitations, challenges, and emerging new multiomics techniques.	Wortmann SB et al.	—	2022	→
Impact of autism genetic risk on brain connectivity: a mechanism for the female protective effect.	Lawrence KE et al.	—	2022	→
Implementation of individualised polygenic risk score analysis: a test case of a family of four.	Corpas M et al.	—	2022	→
Incomplete Penetrance and Variable Expressivity: From Clinical Studies to Population Cohorts.	Kingdom R et al.	—	2022	→
Increased Risk of Preeclampsia in Women With a Genetic Predisposition to Elevated Blood Pressure.	Kivioja A et al.	—	2022	→
Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts.	Steinberg J et al.	—	2022	→
Inferring intelligence of ancient people based on modern genomic studies.	Dauyey K et al.	—	2022	→
Inflammation subtypes in psychosis and their relationships with genetic risk for psychiatric and cardiometabolic disorders.	Zhang L et al.	—	2022	→
Inherited genetics of adult diffuse glioma and polygenic risk scores-a review.	Eckel-Passow JE et al.	—	2022	→
Integration of Genomic Risk Scores to Improve the Prediction of Childhood Asthma Diagnosis.	Kothalawala DM et al.	—	2022	→
Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes.	Tamlander M et al.	—	2022	→
Interaction between blood pressure and genetic risk score for bladder cancer, and risk of urothelial carcinoma in men.	Teleka S et al.	—	2022	→
Interaction between Dietary Fat Intake and Metabolic Genetic Risk Score on 25-Hydroxyvitamin D Concentrations in a Turkish Adult Population.	Isgin-Atici K et al.	—	2022	→
Interaction of polygenic variants specific for abdominal obesity risk with energy metabolism in large Korean cohorts.	Park S	—	2022	→
Interactions between Vitamin D Genetic Risk and Dietary Factors on Metabolic Disease-Related Outcomes in Ghanaian Adults.	Alathari BE et al.	—	2022	→
Interrogating Associations Between Polygenic Liabilities and Electroconvulsive Therapy Effectiveness.	Luykx JJ et al.	—	2022	→
IPRS: Leveraging Gene-Environment Interaction to Reconstruct Polygenic Risk Score.	Tang Y et al.	—	2022	→
Juvenile idiopathic arthritis polygenic risk scores are associated with cardiovascular phenotypes in early adulthood: a phenome-wide association study.	Clarke SLN et al.	—	2022	→
Lack of Support for the Genes by Early Environment Interaction Hypothesis in the Pathogenesis of Schizophrenia.	Vassos E et al.	—	2022	→
Leveraging Therapy-Specific Polygenic Risk Scores to Predict Restrictive Lung Defects in Childhood Cancer Survivors.	Im C et al.	—	2022	→
Life-threatening ventricular arrhythmia prediction in patients with dilated cardiomyopathy using explainable electrocardiogram-based deep neural networks.	Sammani A et al.	—	2022	→
LmTag: functional-enrichment and imputation-aware tag SNP selection for population-specific genotyping arrays.	Thanh Nguyen D et al.	—	2022	→
Machine learning for prediction of schizophrenia using genetic and demographic factors in the UK biobank.	Bracher-Smith M et al.	—	2022	→
Methylation risk scores are associated with a collection of phenotypes within electronic health record systems.	Thompson M et al.	—	2022	→
Molecular genetic mechanisms of congenital heart disease.	Choudhury TZ et al.	—	2022	→
Motives for withdrawal of participation in biobanking and participants' willingness to allow linkages of their data.	Broekstra R et al.	—	2022	→
Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity.	Tsuo K et al.	—	2022	→
Multi-Trait Genetic Analysis Reveals Clinically Interpretable Hypertension Subtypes.	Vaura F et al.	—	2022	→
Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations.	Elgart M et al.	—	2022	→
On the Opportunities and Risks of Examining the Genetics of Entrepreneurship.	Heller B et al.	—	2022	→
Open problems in human trait genetics.	Brandes N et al.	—	2022	→
Organization of gene programs revealed by unsupervised analysis of diverse gene-trait associations.	Mizikovsky D et al.	—	2022	→
Overview of Transcriptomic Research on Type 2 Diabetes: Challenges and Perspectives.	Tonyan ZN et al.	—	2022	→
PAGEANT: personal access to genome and analysis of natural traits.	Huang J et al.	—	2022	→
Personalised Risk Prediction in Hereditary Breast and Ovarian Cancer: A Protocol for a Multi-Centre Randomised Controlled Trial.	Archer S et al.	—	2022	→
Personalized nutrition: A review of genotype-based nutritional supplementation.	Wang F et al.	—	2022	→
Perspectives of diverse Spanish- and English-speaking patients on the clinical use of polygenic risk scores.	Suckiel SA et al.	—	2022	→
Pharmacogenetics of Addiction Therapy.	Graham DP et al.	—	2022	→
Polygenetic Variants Related to Osteoarthritis Risk and Their Interactions with Energy, Protein, Fat, and Alcohol Intake in Adults in a Large Cohort.	Park S	—	2022	→
Polygenic Health Index, General Health, and Pleiotropy: Sibling Analysis and Disease Risk Reduction.	Widen E et al.	—	2022	→
Polygenic heterogeneity in antidepressant treatment and placebo response.	Nøhr AK et al.	—	2022	→
Polygenic prediction of PTSD trajectories in 9/11 responders.	Waszczuk MA et al.	—	2022	→
Polygenic risk, population structure and ongoing difficulties with race in human genetics.	Kaplan JM et al.	—	2022	→
Polygenic risk score: a tool ready for clinical use?	Kavousi M et al.	—	2022	→
Polygenic risk score for embryo selection-not ready for prime time.	Polyakov A et al.	—	2022	→
Polygenic Risk Score Impact on Susceptibility to Age-Related Macular Degeneration in Polish Patients.	Wąsowska A et al.	—	2022	→
Polygenic risk scores for predicting outcomes and treatment response in psychiatry: hope or hype?	Fusar-Poli L et al.	—	2022	→
Polygenic Risk Scores in Alzheimer's Disease Genetics: Methodology, Applications, Inclusion, and Diversity.	Clark K et al.	—	2022	→
Polygenic risk scores of endo-phenotypes identify the effect of genetic background in congenital heart disease.	Spendlove SJ et al.	—	2022	→
Polygenic risk score trend and new variants on chromosome 1 are associated with male gout in genome-wide association study.	Chang YS et al.	—	2022	→
Polygenic scores for schizophrenia and major depression are associated with psychosocial risk factors in children: evidence of gene-environment correlation.	Machlitt-Northen S et al.	—	2022	→
Polygenic Scores in Psychiatry: On the Road From Discovery to Implementation.	Lewis CM et al.	—	2022	→
Polygenic scores: prediction versus explanation.	Plomin R et al.	—	2022	→
Polymorphic Variants of Interleukin-13 R130Q and Interleukin-4 T589C in Children with and without Cow's Milk Allergy.	Matsyura O et al.	—	2022	→
Portability of Polygenic Risk Scores for Sleep Duration, Insomnia and Chronotype in 33,493 Individuals.	Perkiö A et al.	—	2022	→
Preferences for a polygenic test to estimate cancer risk in a general Australian population.	Venning B et al.	—	2022	→
Preschool development, temperament and genetic liability as early markers of childhood ADHD: A cohort study.	Tobarra-Sanchez E et al.	—	2022	→
Proof-of-Principle Study on ECT Illustrates Challenges and Possible Merits of Using Polygenic Risk Scores to Predict Treatment Response in Psychiatry.	Rutten BPF et al.	—	2022	→
Recent advances in understanding the genetic basis of systemic lupus erythematosus.	Ha E et al.	—	2022	→
Role of Polygenic Risk Score in the Familial Transmission of Bipolar Disorder in Youth.	Birmaher B et al.	—	2022	→
Should preimplantation genetic testing for polygenic disease be offered to all - or none?	Treff NR et al.	—	2022	→
Significant sparse polygenic risk scores across 813 traits in UK Biobank.	Tanigawa Y et al.	—	2022	→
Study of the Combined Effect of Maternal Tobacco Smoking and Polygenic Risk Scores on Birth Weight and Body Mass Index in Childhood.	Fuentes-Paez G et al.	—	2022	→
Sustainable infrastructure and risk stratification are needed to appropriately deliver colorectal cancer screening globally.	Coronado GD	—	2022	→
Systematic comparison of family history and polygenic risk across 24 common diseases.	Mars N et al.	—	2022	→
Ten challenges for clinical translation in psychiatric genetics.	Derks EM et al.	—	2022	→
Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa.	Kim MS et al.	—	2022	→
The construction of cross-population polygenic risk scores using transfer learning.	Zhao Z et al.	—	2022	→
The False Dawn of Polygenic Risk Scores for Human Disease Prediction.	Herzig AF et al.	—	2022	→
The Polygenic Risk Score Knowledge Base offers a centralized online repository for calculating and contextualizing polygenic risk scores.	Page ML et al.	—	2022	→
The Promise and Peril of Genetics.	Dick DM	—	2022	→
The role of ADHD genetic risk in mid-to-late life somatic health conditions.	Garcia-Argibay M et al.	—	2022	→
The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice.	Forzano F et al.	—	2022	→
Transferability of genetic risk scores in African populations.	Kamiza AB et al.	—	2022	→
Twelve Variants Polygenic Score for Low-Density Lipoprotein Cholesterol Distribution in a Large Cohort of Patients With Clinically Diagnosed Familial Hypercholesterolemia With or Without Causative Mutations.	Olmastroni E et al.	—	2022	→
Using a Polygenic Score to Predict the Risk of Developing Primary Osteoporosis.	Yalaev B et al.	—	2022	→
Using Polygenic Risk Scores Related to Complex Traits to Predict Production Performance in Cross-Breeding of Yeast.	Dai Y et al.	—	2022	→
What Do We Know About the Genetic Architecture of Psychopathology?	Giangrande EJ et al.	—	2022	→
Working memory and reaction time variability mediate the relationship between polygenic risk and ADHD traits in a general population sample.	Moses M et al.	—	2022	→
A 6-CpG validated methylation risk score model for metabolic syndrome: The HyperGEN and GOLDN studies.	Hidalgo BA et al.	—	2021	→
Advancing drug discovery using the power of the human genome.	Heilbron K et al.	—	2021	→
A Genome-Wide Association Study and Polygenic Risk Score Analysis of Posttraumatic Stress Disorder and Metabolic Syndrome in a South African Population.	Swart PC et al.	—	2021	→
A Network-Based Analysis of Disease Complication Associations for Obstetric Disorders in the UK Biobank.	Sriram V et al.	—	2021	→
A novel transcriptional risk score for risk prediction of complex human diseases.	Shan N et al.	—	2021	→
A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease.	Rampersaud E et al.	—	2021	→
Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review.	Kenner B et al.	—	2021	→
A systematic review and meta-analysis of host genetic factors associated with influenza severity.	Van Goethem N et al.	—	2021	→
A unified framework for cross-population trait prediction by leveraging the genetic correlation of polygenic traits.	Cai M et al.	—	2021	→
Body Mass Index and Birth Weight Improve Polygenic Risk Score for Type 2 Diabetes.	Moldovan A et al.	—	2021	→
Can polygenic risk scores help identify pediatric bipolar spectrum and related disorders?: A systematic review.	Biederman J et al.	—	2021	→
Childhood exposure to ambient air pollution and predicting individual risk of depression onset in UK adolescents.	Latham RM et al.	—	2021	→
Chronic Irritability in Youth: A Reprise on Challenges and Opportunities Toward Meeting Unmet Clinical Needs.	Leibenluft E et al.	—	2021	→
Clinical utility of polygenic risk scores for predicting NAFLD disorders.	Dessein A	—	2021	→
Concordance rate in cattle and sheep between genotypes differing in Illumina GenCall quality score.	Berry DP et al.	—	2021	→
Contribution of genetic ancestry and polygenic risk score in meeting vitamin B12 needs in healthy Brazilian children and adolescents.	Fuzo CA et al.	—	2021	→
Design and user experience testing of a polygenic score report: a qualitative study of prospective users.	Brockman DG et al.	—	2021	→
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.	Goodrich JK et al.	—	2021	→
Development and Validation of Decision Rules Models to Stratify Coronary Artery Disease, Diabetes, and Hypertension Risk in Preventive Care: Cohort Study of Returning UK Biobank Participants.	Castela Forte J et al.	—	2021	→
Diagnosis and Risk Prediction of Dilated Cardiomyopathy in the Era of Big Data and Genomics.	Sammani A et al.	—	2021	→
Dissecting autism and schizophrenia through neuroimaging genomics.	Moreau CA et al.	—	2021	→
DNA double-strand break repair in cancer: A path to achieving precision medicine.	Gillyard T et al.	—	2021	→
Epicardial Adipose Tissue: The Genetics Behind an Emerging Cardiovascular Risk Marker.	Sousa JA et al.	—	2021	→
Epidemiology and risk-stratification of NAFLD-associated HCC.	Ioannou GN	—	2021	→
Evaluation of polygenic prediction methodology within a reference-standardized framework.	Pain O et al.	—	2021	→
From Basic Science to Clinical Application of Polygenic Risk Scores: A Primer.	Wray NR et al.	—	2021	→
From Personalized Medicine to Precision Psychiatry?	Češková E et al.	—	2021	→
Genetic Advances in Autism.	Thapar A et al.	—	2021	→
Genetically determined risk of keratinocyte carcinoma and risk of other cancers.	Dusingize JC et al.	—	2021	→
Genetic architecture of schizophrenia: a review of major advancements.	Legge SE et al.	—	2021	→
Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke Studies.	Armstrong ND et al.	—	2021	→
Genetic prediction of complex traits with polygenic scores: a statistical review.	Ma Y et al.	—	2021	→
Genetic Risk for Overall Cancer and the Benefit of Adherence to a Healthy Lifestyle.	Zhu M et al.	—	2021	→
Genetic Risk Prediction of COVID-19 Susceptibility and Severity in the Indian Population.	Prakrithi P et al.	—	2021	→
Genetic risk score for ovarian cancer based on chromosomal-scale length variation.	Toh C et al.	—	2021	→
Genetics Is of the Essence to Face NAFLD.	Meroni M et al.	—	2021	→
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.	Mullins N et al.	—	2021	→
GeNuIne (gene-nutrient interactions) Collaboration: towards implementing multi-ethnic population-based nutrigenetic studies of vitamin B<sub>12</sub> and D deficiencies and metabolic diseases.	Vimaleswaran KS	—	2021	→
Identification of Germline Genetic Variants that Increase Prostate Cancer Risk and Influence Development of Aggressive Disease.	Saunders EJ et al.	—	2021	→
Interactions Between Kidney Function and Cerebrovascular Disease: Vessel Pathology That Fires Together Wires Together.	Marini S et al.	—	2021	→
Interactions between Polygenic Risk Scores, Dietary Pattern, and Menarche Age with the Obesity Risk in a Large Hospital-Based Cohort.	Park S et al.	—	2021	→
Investigating perceived heritability of mental health disorders and attitudes toward genetic testing in the United States, United Kingdom, and Australia.	Morosoli JJ et al.	—	2021	→
Knowledge, views and expectations for cancer polygenic risk testing in clinical practice: A cross-sectional survey of health professionals.	Smit AK et al.	—	2021	→
Machine and Deep Learning in Molecular and Genetic Aspects of Sleep Research.	Elgart M et al.	—	2021	→
Machine learning based disease prediction from genotype data.	Katsaouni N et al.	—	2021	→
Machine learning for the life-time risk prediction of Alzheimer's disease: a systematic review.	Rowe TW et al.	—	2021	→
Machine Learning Prediction of Biomarkers from SNPs and of Disease Risk from Biomarkers in the UK Biobank.	Widen E et al.	—	2021	→
Molecular Genetics and Complex Inheritance of Congenital Heart Disease.	Diab NS et al.	—	2021	→
Multi-Omic Approaches to Identify Genetic Factors in Metabolic Syndrome.	Clark KC et al.	—	2021	→
Non-communicable diseases pandemic and precision medicine: Is Africa ready?	Chikowore T et al.	—	2021	→
Novel risk factors for craniofacial microsomia and assessment of their utility in clinic diagnosis.	Xu X et al.	—	2021	→
Nutrigenetics and nutrigenomics-A personalized approach to nutrition.	Ahluwalia MK	—	2021	→
Obstetric Complications and Polygenic Risk Score: Which Role in Predicting a Severe Short-Term Outcome in Psychosis?	Tosato S et al.	—	2021	→
Of Screening, Stratification, and Scores.	Knoppers BM et al.	—	2021	→
Optimal cholesterol treatment plans and genetic testing strategies for cardiovascular diseases.	Marrero WJ et al.	—	2021	→
Polygenetic risk scores do not add predictive power to clinical models for response to anti-TNFα therapy in inflammatory bowel disease.	Karmi N et al.	—	2021	→
Polygenic Risk Score for Alzheimer's Disease in Caribbean Hispanics.	Sariya S et al.	—	2021	→
Polygenic risk score for genetic evaluation of prostate cancer risk in Asian populations: A narrative review.	Song SH et al.	—	2021	→
Polygenic Risk Score Prediction for Endometriosis.	Kloeve-Mogensen K et al.	—	2021	→
Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues.	Lewis ACF et al.	—	2021	→
Polygenic risk scores: the future of cancer risk prediction, screening, and precision prevention.	Wang Y et al.	—	2021	→
Polygenic Scores for Cognitive Abilities and Their Association with Different Aspects of General Intelligence-A Deep Phenotyping Approach.	Genç E et al.	—	2021	→
Postictal Psychosis in Epilepsy: A Clinicogenetic Study.	Braatz V et al.	—	2021	→
Potential Genetic Overlap Between Insomnia and Sleep Symptoms in Major Depressive Disorder: A Polygenic Risk Score Analysis.	Melhuish Beaupre LM et al.	—	2021	→
Precision Medicine in Kidney Transplantation: Just Hype or a Realistic Hope?	Nobakht E et al.	—	2021	→
Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment.	Pyun JM et al.	—	2021	→
Prenatal Particulate Matter Exposure Is Associated with Saliva DNA Methylation at Age 15: Applying Cumulative DNA Methylation Scores as an Exposure Biomarker.	Bakulski KM et al.	—	2021	→
Problems with Using Polygenic Scores to Select Embryos.	Turley P et al.	—	2021	→
Prognostic value of polygenic risk scores for adults with psychosis.	Landi I et al.	—	2021	→
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma.	Mohammed Y et al.	—	2021	→
Recent innovations and in-depth aspects of post-genome wide association study (Post-GWAS) to understand the genetic basis of complex phenotypes.	Mortezaei Z et al.	—	2021	→
Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps.	Polygenic Risk Score Task Force of the International Common Disease Alliance	—	2021	→
Risk factors predicting the occurrence of metachronous ovarian metastasis of gastric cancer.	Gao J et al.	—	2021	→
Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression.	Mo A et al.	—	2021	→
Systematic Review: How the Attention-Deficit/Hyperactivity Disorder Polygenic Risk Score Adds to Our Understanding of ADHD and Associated Traits.	Ronald A et al.	—	2021	→
Systems Biology Guided Gene Enrichment Approaches Improve Prediction of Chronic Post-surgical Pain After Spine Fusion.	Chidambaran V et al.	—	2021	→
The association between loneliness and depressive symptoms among adults aged 50 years and older: a 12-year population-based cohort study.	Lee SL et al.	—	2021	→
The association of sex, age and FKBP5 genotype with common somatic symptoms: A replication study in the lifelines cohort study.	Ballering AV et al.	—	2021	→
The clinical applicability of polygenic risk scores for LDL-cholesterol: considerations, current evidence and future perspectives.	Cupido AJ et al.	—	2021	→
The Differential Influence of Immune, Endocytotic, and Lipid Metabolism Genes on Amyloid Deposition and Neurodegeneration in Subjects at Risk of Alzheimer's Disease.	Femminella GD et al.	—	2021	→
The genetic basis of major depression.	Kendall KM et al.	—	2021	→
The Identifying Depression Early in Adolescence Risk Stratified Cohort (IDEA-RiSCo): Rationale, Methods, and Baseline Characteristics.	Kieling C et al.	—	2021	→
The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network.	Selenius JS et al.	—	2021	→
The Translational Machine: A novel machine-learning approach to illuminate complex genetic architectures.	Askland KD et al.	—	2021	→
Towards Building a Quantitative Proteomics Toolbox in Precision Medicine: A Mini-Review.	Correa Rojo A et al.	—	2021	→
Vitamin D and the risk of treatment-resistant and atypical depression: A Mendelian randomization study.	Arathimos R et al.	—	2021	→
What Have We Learned About the Genetics of Obsessive-Compulsive and Related Disorders in Recent Years?	Mattheisen M et al.	—	2021	→
Where the genome meets the connectome: Understanding how genes shape human brain connectivity.	Arnatkeviciute A et al.	—	2021	→
A large-scale genome-wide association study meta-analysis of cannabis use disorder.	Johnson EC et al.	—	2020	→
An update on genetic risk scores for coronary artery disease: are they useful for predicting disease risk and guiding clinical decisions?	Lieb W et al.	—	2020	→
Barriers to Implementing Clinical Pharmacogenetics Testing in Sub-Saharan Africa. A Critical Review.	B Tata E et al.	—	2020	→
Delineation of clinical and biological factors associated with cutaneous squamous cell carcinoma among patients with chronic lymphocytic leukemia.	Kleinstern G et al.	—	2020	→
Genetic control of non-genetic inheritance in mammals: state-of-the-art and perspectives.	Tomar A et al.	—	2020	→
Genetic Hypothesis and Pharmacogenetics Side of Renin-Angiotensin-System in COVID-19.	Gemmati D et al.	—	2020	→
How to Utilize Clinical and Genetic Information for Personalized Treatment of Major Depressive Disorder: Step by Step Strategic Approach.	Fabbri C et al.	—	2020	→
MethylDetectR: a software for methylation-based health profiling.	Hillary RF et al.	—	2020	→
Molecular Genetics of Glaucoma: Subtype and Ethnicity Considerations.	Zukerman R et al.	—	2020	→
Nature, Nurture, and the Polygenic Risk Score for Schizophrenia.	Murray RM et al.	—	2020	→
Risk Stratification for Bipolar Disorder Using Polygenic Risk Scores Among Young High-Risk Adults.	Biere S et al.	—	2020	→
Using Genetics to Increase Specificity of Outcome Prediction in Psychiatric Disorders: Prospects for Progression.	Holmans PA	—	2020	→