dopamine drug

Aliases

DA, Dopamine, [DA], [DA]s, dopamine, dopamine activity, dopamine neurotransmission, dopamine signaling, dopamine system, dopamine transients, dopaminergic, dopaminergic activity, dopaminergic function, dopaminergic neurons, dopaminergic neurotransmission, dopaminergic signal, dopaminergic signals, dopaminergic system, extracellular dopamine, monoamine dopamine, rapid dopamine signaling, reward-sensitive dopamine system

External links

DrugBank · PubChem

Related entities (219)

Mentioned in (227)

Papers in which this entity is mentioned.

• High-Parameter Spatial Multi-Omics through Histology-Anchored Integration (2025)
• Emotion, motivation, decision-making, the orbitofrontal cortex, anterior cingulate cortex, and the amygdala. (2023)
• Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. (2023)
• Altered dendritic morphology in dorsolateral prefrontal cortex of nonhuman primates prenatally exposed to maternal immune activation. (2023)
• Embryonic Nicotine Exposure Disrupts Adult Social Behavior and Craniofacial Development in Zebrafish. (2022)
• Genetic variants associated with longitudinal changes in brain structure across the lifespan. (2022)
• Transcriptional and anatomical diversity of medium spiny neurons in the primate striatum. (2021)
• Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions. (2021)
• An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder. (2021)
• Toward a neurocircuit-based taxonomy to guide treatment of obsessive-compulsive disorder. (2021)
• Sex/gender differences in brain function and structure in alcohol use: A narrative review of neuroimaging findings over the last 10 years. (2021)
• The role of oxytocin in alcohol and drug abuse. (2020)
• gene network in the prefrontal cortex is associated with total brain volume in childhood. (2020)
• Using rat operant delayed match-to-sample task to identify neural substrates recruited with increased working memory load. (2020)
• TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson's Disease. (2020)
• Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
• DNA methylation and brain structure and function across the life course: A systematic review. (2020)
• Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative review. (2020)
• Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome. (2020)
• Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. (2020)
• Peripheral Biomarkers for First-Episode Psychosis-Opportunities from the Neuroinflammatory Hypothesis of Schizophrenia. (2019)
• A review on neuroimaging studies of genetic and environmental influences on early brain development. (2019)
• Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. (2019)
• Prenatal Stress and Maternal Immune Dysregulation in Autism Spectrum Disorders: Potential Points for Intervention. (2019)
• Transient Potassium Channels: Therapeutic Targets for Brain Disorders. (2019)
• Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. (2019)
• Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. (2019)
• Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. (2018)
• mTORC2 in the dorsomedial striatum of mice contributes to alcohol-dependent F-Actin polymerization, structural modifications, and consumption. (2018)
• Oxytocin Receptor Gene Variant Interacts with Intervention Delivery Format in Predicting Intervention Outcomes for Youth with Conduct Problems. (2018)
• The neural correlates of the unified percept of alcohol-related craving: a fMRI and EEG study. (2018)
• Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review. (2018)
• Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain. (2018)
• Neuroepigenetics and addiction. (2018)
• Hemispheric brain asymmetry differences in youths with attention-deficit/hyperactivity disorder. (2018)
• The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development. (2018)
• Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. (2018)
• Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017)
• Genetic studies of alcohol dependence in the context of the addiction cycle. (2017)
• The acute effect of cannabis on plasma, liver and brain ammonia dynamics, a translational study. (2017)
• Long-term behavioral change as a result of acute ethanol exposure in zebrafish: Evidence for a role for sonic hedgehog but not retinoic acid signaling. (2017)
• Functional Connectivity of the Infant Human Brain: Plastic and Modifiable. (2017)
• Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models. (2017)
• CHN2 Promoter Methylation Change May Be Associated With Methamphetamine Dependence. (2017)
• Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans. (2017)
• Environmental factors influencing the risk of autism. (2017)
• Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits. (2017)
• Refinement of learned skilled movement representation in motor cortex deep output layer. (2017)
• De Novo Coding Variants Are Strongly Associated with Tourette Disorder. (2017)
• Effect of Neuroinflammation on Synaptic Organization and Function in the Developing Brain: Implications for Neurodevelopmental and Neurodegenerative Disorders. (2017)
• Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential. (2017)
• Alterations of resting state functional network connectivity in the brain of nicotine and alcohol users. (2017)
• Longitudinal epigenetic predictors of amygdala:hippocampus volume ratio. (2017)
• Perinatal maternal alcohol consumption and methylation of the dopamine receptor in the offspring: the Triple B study. (2016)
• The role of active DNA demethylation and Tet enzyme function in memory formation and cocaine action. (2016)
• Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity. (2016)
• Corticostriatal circuitry. (2016)
• Mechanisms in the relation between GABRA2 and adolescent externalizing problems. (2016)
• Neurobiological phenotypes associated with a family history of alcoholism. (2016)
• Effects of early life stress on amygdala and striatal development. (2016)
• Pre- and Post-Natal Maternal Depressive Symptoms in Relation with Infant Frontal Function, Connectivity, and Behaviors. (2016)
• Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage. (2016)
• The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming. (2016)
• Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. (2016)
• Oxidative stress signaling to chromatin in health and disease. (2016)
• RNA splicing is a primary link between genetic variation and disease. (2016)
• Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors. (2015)
• Genome-Wide DNA Methylation Profiling Reveals Epigenetic Changes in the Rat Nucleus Accumbens Associated With Cross-Generational Effects of Adolescent THC Exposure. (2015)
• Executive function and cortical thickness in youths prenatally exposed to cocaine, alcohol and tobacco. (2015)
• Impairment of social behaviour persists two years after embryonic alcohol exposure in zebrafish: A model of fetal alcohol spectrum disorders. (2015)
• A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism. (2015)
• Longitudinal changes in adolescent risk-taking: a comprehensive study of neural responses to rewards, pubertal development, and risk-taking behavior. (2015)
• Candidate gene-environment interaction research: reflections and recommendations. (2015)
• Interparental Relationship Sensitivity Leads to Adolescent Internalizing Problems: Different Genotypes, Different Pathways. (2015)
• Functional Connectivity Disruption in Neonates with Prenatal Marijuana Exposure. (2015)
• Embryonic alcohol exposure impairs the dopaminergic system and social behavioral responses in adult zebrafish. (2015)
• Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms. (2015)
• Prenatal drug exposure affects neonatal brain functional connectivity. (2015)
• Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex. (2015)
• Strain dependent neurochemical changes induced by embryonic alcohol exposure in zebrafish. (2014)
• The Effects of Arsenic Exposure on Neurological and Cognitive Dysfunction in Human and Rodent Studies: A Review. (2014)
• Moderator effects of working memory on the stability of ADHD symptoms by dopamine receptor gene polymorphisms during development. (2014)
• Dissecting impulsivity and its relationships to drug addictions. (2014)
• Ethanol and cocaine: environmental place conditioning, stereotypy, and synergism in planarians. (2014)
• Heritability and molecular-genetic basis of the P3 event-related brain potential: a genome-wide association study. (2014)
• Induced neuronal reprogramming. (2014)
• Pharmacogenetics of OPRM1. (2014)
• Modelling cognitive affective biases in major depressive disorder using rodents. (2014)
• Effects of Acute Prenatal Exposure to Ethanol on microRNA Expression are Ameliorated by Social Enrichment. (2014)
• Neuronal substrates and functional consequences of prenatal cannabis exposure. (2014)
• Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study. (2014)
• Cannabis controversies: how genetics can inform the study of comorbidity. (2014)
• Genetic influences on brain developmental trajectories on neuroimaging studies: from infancy to young adulthood. (2014)
• Epigenetics, microRNA, and addiction. (2014)
• Baths salts, spice, and related designer drugs: the science behind the headlines. (2014)
• Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? (2014)
• The influence of puberty on subcortical brain development. (2014)
• Association of PER2 genotype and stressful life events with alcohol drinking in young adults. (2013)
• Regional brain morphometry and impulsivity in adolescents following prenatal exposure to cocaine and tobacco. (2013)
• Cyclic adenosine monophosphate and brain-derived neurotrophic factor decreased oxidative stress and apoptosis in developing hypothalamic neuronal cells: role of microglia. (2013)
• Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings. (2013)
• COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers. (2013)
• Rethinking schizophrenia in the context of normal neurodevelopment. (2013)
• Maturation of the adolescent brain. (2013)
• Effects of alcohol on the endocrine system. (2013)
• Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents. (2013)
• Basal regulation of HPA and dopamine systems is altered differentially in males and females by prenatal alcohol exposure and chronic variable stress. (2013)
• Association of PER2 genotype and stressful life events with alcohol drinking in young adults. (2013)
• Prenatal maternal depression symptoms and nutrition, and child cognitive function. (2013)
• Synaptic effects induced by alcohol. (2013)
• Stress-related neuropeptides and addictive behaviors: beyond the usual suspects. (2012)
• Strain dependent gene expression and neurochemical levels in the brain of zebrafish: focus on a few alcohol related targets. (2012)
• Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective. (2012)
• Neural systems supporting cognitive-affective interactions in adolescence: the role of puberty and implications for affective disorders. (2012)
• Does moderate drinking harm the fetal brain? Insights from animal models. (2012)
• The aggregate effect of dopamine genes on dependence symptoms among cocaine users: cross-validation of a candidate system scoring approach. (2012)
• Circadian genes, the stress axis, and alcoholism. (2012)
• Selective effects of perinatal ethanol exposure in medial prefrontal cortex and nucleus accumbens. (2012)
• An anatomically comprehensive atlas of the adult human brain transcriptome. (2012)
• Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012)
• The genetics of alcohol dependence: advancing towards systems-based approaches. (2012)
• Withdrawal from THC during adolescence: sex differences in locomotor activity and anxiety. (2012)
• Multiple dynamic representations in the motor cortex during sensorimotor learning. (2012)
• Adolescents with prenatal cocaine exposure show subtle alterations in striatal surface morphology and frontal cortical volumes. (2012)
• Effects of prenatal exposure to sodium arsenite on motor and food-motivated behaviors from birth to adulthood in C57BL6/J mice. (2012)
• Glutamatergic transmission in schizophrenia: from basic research to clinical practice. (2012)
• The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. (2012)
• The genetic basis of addictive disorders. (2012)
• Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. (2012)
• Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. (2012)
• The impact of gene-environment interaction on alcohol use disorders. (2012)
• Dissociable effects of methylphenidate, atomoxetine and placebo on regional cerebral blood flow in healthy volunteers at rest: a multi-class pattern recognition approach. (2012)
• Exploration and modulation of brain network interactions with noninvasive brain stimulation in combination with neuroimaging. (2012)
• Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence. (2012)
• Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012)
• The genetics of the opioid system and specific drug addictions. (2012)
• Assessing the impact of nicotine dependence genes on the risk of facial clefts: An example of the use of national registry and biobank data. (2012)
• Cholinergic modulation of synaptic integration and dendritic excitability in the striatum. (2011)
• Association among SNAP-25 gene DdeI and MnlI polymorphisms and hemodynamic changes during methylphenidate use: a functional near-infrared spectroscopy study. (2011)
• The effects of prenatal alcohol exposure on behavior: rodent and primate studies. (2011)
• A genetic determinant of the striatal dopamine response to alcohol in men. (2011)
• Developmental trajectories during adolescence in males and females: a cross-species understanding of underlying brain changes. (2011)
• Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. (2011)
• Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway. (2011)
• Human aggression across the lifespan: genetic propensities and environmental moderators. (2011)
• Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls. (2011)
• Abnormal brain activation during working memory in children with prenatal exposure to drugs of abuse: the effects of methamphetamine, alcohol, and polydrug exposure. (2011)
• Epigenetics and psychoneuroimmunology: mechanisms and models. (2011)
• Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord. (2011)
• Pharmacological treatment of cannabis dependence. (2011)
• Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors. (2011)
• Prenatal methamphetamine exposure and neonatal neurobehavioral outcome in the USA and New Zealand. (2011)
• Transcriptional and epigenetic mechanisms of addiction. (2011)
• Recent research on impulsivity in individuals with drug use and mental health disorders: implications for alcoholism. (2010)
• Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients. (2010)
• Adolescent development of the reward system. (2010)
• Alcohol during adolescence selectively alters immediate and long-term behavior and neurochemistry. (2010)
• Dysfunctional reward processing in male alcoholics: an ERP study during a gambling task. (2010)
• Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010)
• Association study of 182 candidate genes in anorexia nervosa. (2010)
• Distinguishing between attention-deficit hyperactivity and fetal alcohol spectrum disorders in children: clinical guidelines. (2010)
• Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease. (2010)
• Conserved role of unc-79 in ethanol responses in lightweight mutant mice. (2010)
• A behavioral scientist looks at the science of adolescent brain development. (2010)
• Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. (2010)
• Disrupted functional connectivity with dopaminergic midbrain in cocaine abusers. (2010)
• Is there an inhibitory-response-control system in the rat? Evidence from anatomical and pharmacological studies of behavioral inhibition. (2010)
• Muscarinic type 2 receptors in the lateral dorsal tegmental area modulate cocaine and food seeking behavior in rats. (2010)
• Structural, metabolic, and functional brain abnormalities as a result of prenatal exposure to drugs of abuse: evidence from neuroimaging. (2010)
• Neurobiology of the adolescent brain and behavior: implications for substance use disorders. (2010)
• Role of microglia in ethanol's apoptotic action on hypothalamic neuronal cells in primary cultures. (2010)
• Cocaine exposure modulates dopamine and adenosine signaling in the fetal brain. (2010)
• Differentiating prenatal exposure to methamphetamine and alcohol versus alcohol and not methamphetamine using tensor-based brain morphometry and discriminant analysis. (2010)
• Neural encoding of cocaine-seeking behavior is coincident with phasic dopamine release in the accumbens core and shell. (2009)
• Prenatal exposure to drugs: effects on brain development and implications for policy and education. (2009)
• Cannabis and psychosis/schizophrenia: human studies. (2009)
• Anatomical characterization of human fetal brain development with diffusion tensor magnetic resonance imaging. (2009)
• Nicotine withdrawal sensitivity, linkage to chr6q26, and association of OPRM1 SNPs in the SMOking in FAMilies (SMOFAM) sample. (2009)
• Deletion of glycine transporter 1 (GlyT1) in forebrain neurons facilitates reversal learning: enhanced cognitive adaptability? (2009)
• Fetal effects of psychoactive drugs. (2009)
• Blood glucose level, alcohol heavy drinking, and alcohol craving during treatment for alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) Study. (2009)
• Low and High Gamma Oscillations in Rat Ventral Striatum have Distinct Relationships to Behavior, Reward, and Spiking Activity on a Learned Spatial Decision Task. (2009)
• Altered neurometabolites and motor integration in children exposed to methamphetamine in utero. (2009)
• Executive cognitive functions and impulsivity as correlates of risk taking and problem behavior in preadolescents. (2009)
• Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. (2009)
• Neurotoxic effects and biomarkers of lead exposure: a review. (2009)
• Neuroimaging of children following prenatal drug exposure. (2009)
• How do emotion and motivation direct executive control? (2009)
• Response inhibition among early adolescents prenatally exposed to tobacco: an fMRI study. (2009)
• Neuroimaging of children following prenatal drug exposure. (2009)
• Neuroimaging and fetal alcohol spectrum disorders. (2009)
• A new perspective on the role of the orbitofrontal cortex in adaptive behaviour. (2009)
• The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. (2009)
• Children with and without gestational cocaine exposure: a neurocognitive systems analysis. (2009)
• Genome-wide and candidate gene association study of cigarette smoking behaviors. (2009)
• Protein kinases and addiction. (2008)
• The error-related negativity (ERN) and psychopathology: toward an endophenotype. (2008)
• Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. (2008)
• Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
• Association study of Wnt signaling pathway genes in bipolar disorder. (2008)
• EEG biofeedback as a treatment for substance use disorders: review, rating of efficacy, and recommendations for further research. (2008)
• How do the basal ganglia contribute to categorization? Their roles in generalization, response selection, and learning via feedback. (2008)
• Clock genes running amok. Clock genes and their role in drug addiction and depression. (2007)
• Genetic and environmental factors in complex neurodevelopmental disorders. (2007)
• Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes. (2007)
• Efficiency and cost of economical brain functional networks. (2007)
• Season of birth and dopamine receptor gene associations with impulsivity, sensation seeking and reproductive behaviors. (2007)
• Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. (2007)
• Maternal immune activation alters fetal brain development through interleukin-6. (2007)
• Updating P300: an integrative theory of P3a and P3b. (2007)
• Causes and consequences of methamphetamine and MDMA toxicity. (2006)
• Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism. (2006)
• Sexually dimorphic synaptic organization of the medial amygdala. (2005)
• Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. (2004)
• Structural abnormalities in the brains of human subjects who use methamphetamine. (2004)
• Alcoholism and human electrophysiology. (2003)
• Associative learning elicits the formation of multiple-synapse boutons. (2001)
• In utero cocaine-induced dysfunction of dopamine D1 receptor signaling and abnormal differentiation of cerebral cortical neurons. (2000)
• Modeling alcohol's effects on organs in animal models. (2000)
• The role of stress in alcohol use, alcoholism treatment, and relapse. (1999)
• Effect of enriched environment rearing on impairments in cortical excitability and plasticity after prenatal alcohol exposure. (1999)
• Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428. (1998)
• The endocrine system: alcohol alters critical hormonal balance. (1997)
• Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor. (1997)
• Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. (1996)
• Axons of early generated neurons in cingulate cortex pioneer the corpus callosum. (1994)
• The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. (1993)

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