The risk for persistent adult alcohol and nicotine dependence: the role of childhood maltreatment.
paper
Cited
Public
- Authors
- Elliott, Jennifer C; Stohl, Malka; Wall, Melanie M; Keyes, Katherine M; Goodwin, Renee D; Skodol, Andrew E; Krueger, Robert F; Grant, Bridget F; Hasin, Deborah S
- Year
- 2014
- Journal
- Addiction (Abingdon, England)
- PMID
- 24401044
- DOI
- 10.1111/add.12477
- PMCID
- PMC3984602
BACKGROUND AND AIMS: Alcohol and nicotine dependence are associated with considerable morbidity and mortality, especially when cases are persistent. The risk for alcohol and nicotine dependence is increased by childhood maltreatment. However, the influence of childhood maltreatment on dependence course is unknown, and is evaluated in the current study. DESIGN: Physical, sexual and emotional abuse, and physical and emotional neglect, were evaluated as predictors of persistent alcohol and nicotine dependence over 3 years of follow-up, with and without control for other childhood adversities. SETTING: National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). PARTICIPANTS: NESARC participants completing baseline and follow-up who met criteria at baseline for past-year alcohol dependence (n = 1172) and nicotine dependence (n = 4017). MEASUREMENTS: Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS) measures of alcohol/nicotine dependence, childhood maltreatment and other adverse childhood experiences (e.g. parental divorce). FINDINGS: Controlling for demographics only, physical, sexual and emotional abuse and physical neglect predicted 3-year persistence of alcohol dependence [adjusted odds ratio (AOR) = 1.50-2.99; 95% CI = 1.04-4.68] and nicotine dependence (AOR = 1.37-1.74; 95% CI = 1.13-2.11). With other childhood adversities also controlled, maltreatment types remained predictive for alcohol persistence (AOR = 1.53-3.02; 95% CI = 1.07-4.71) and nicotine persistence (AOR = 1.35-1.72; 95% CI = 1.11-2.09). Further, a greater number of maltreatment types incrementally influenced persistence risk (AOR = 1.19-1.36; 95% CI = 1.11-1.56). CONCLUSIONS: A history of childhood maltreatment predicts persistent adult alcohol and nicotine dependence. This association, robust to control for other childhood adversities, suggests that maltreatment (rather than a generally difficult childhood) affects the course of dependence.
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Intergenerational transmission of maternal childhood maltreatment, prenatal substance exposure, and internalizing and externalizing symptoms in early adolescence at age 12. | Min MO et al. | — | 2026 | → |
| The impact of childhood emotional maltreatment on adulthood smoking behaviour: A systematic review and narrative synthesis. | Lu Q et al. | — | 2026 | → |
| Characterization of inflammatory and neurofunctional markers in the context of early life stress among a clinical sample of people maintained on buprenorphine for opioid use disorder. | Marcus MM et al. | — | 2025 | → |
| Child maltreatment elevated the risk of late-life chronic pain: a biopsychosocial framework from the UK Biobank cohort. | Zhao W et al. | — | 2025 | → |
| Exogenous Correlates of Substance Use Among Youth Who Have Experienced Maltreatment and Child Welfare Involvement. | Nisle-Mikos S et al. | — | 2025 | → |
| Pathways From Childhood Maltreatment to Adult Drug Use: The Distinct Roles of Internalizing and Externalizing Symptoms. | Javakhishvili M et al. | — | 2025 | → |
| Patterns of childhood maltreatment and maternal substance use disorder on the development of emerging adult offspring substance use. | Ross AJ et al. | — | 2025 | → |
| Serial mediation of perceived stress and depression in the relationship between childhood trauma and mobile phone addiction among undergraduate nursing students in China: a cross-sectional questionnaire survey. | Li H et al. | — | 2025 | → |
| Shame, guilt, and drinking motives as mediators between child maltreatment and problematic alcohol use in college students. | Julian K et al. | — | 2025 | → |
| Interventions for prevention and treatment of substance use in youth with traumatic childhood experiences: a systematic review and synthesis of the literature. | Becker TD et al. | — | 2024 | → |
| Relations between childhood psychological maltreatment and mental health dimensions within a higher-order model. | Xiao Z et al. | — | 2024 | → |
| The relationship between childhood trauma and internet addiction in adolescents: A meta-analysis. | Tang H et al. | — | 2024 | → |
| The relative effects of parental alcohol use disorder and maltreatment on offspring alcohol use: Unique pathways of risk. | Ross AJ et al. | — | 2024 | → |
| Tobacco use behavior among adults exposed to cumulative adverse childhood experiences: A systematic review and meta analysis. | Abufarsakh B et al. | — | 2024 | → |
| Trauma and mental health in Pacific Islanders. | Subica AM et al. | — | 2024 | → |
| Adverse Childhood Experiences and Pathways to Violent Behavior for Women and Men. | Burke C et al. | — | 2023 | → |
| Childhood Traumatic Experiences and Negative Alcohol-Related Consequences in Adulthood: A Cross-Cultural Examination of Distress Tolerance and Drinking to Cope. | Norton EO et al. | — | 2023 | → |
| Sex/gender differences in the associations between adverse childhood experiences and intimate partner violence with mental disorders. | Cavanaugh C et al. | — | 2023 | → |
| The Impact of Childhood Traumatization on Diabetes Mellitus Type 2 Risk in World War II Refugees and Their Offspring. | Wildenberg KS et al. | — | 2023 | → |
| The mediating role of self-regulation on the link between child maltreatment and later substance use among Latinx youth. | Cooper DK et al. | — | 2023 | → |
| Associations of childhood trauma with long-term diseases and alcohol and nicotine use disorders in Czech and Slovak representative samples. | Kascakova N et al. | — | 2022 | → |
| Intergenerational Effect of Maternal Childhood Maltreatment on Next Generation's Vulnerability to Psychopathology: A Systematic Review With Meta-Analysis. | Su Y et al. | — | 2022 | → |
| Role of Risk Taking and Inhibitory Control in Alcohol Use Among Maltreated Adolescents and Nonmaltreated Adolescents. | Kim HK et al. | — | 2022 | → |
| A Comparison of the Smoking Outcomes of Self-reported and Agency-Notified Child Abuse in a Population-Based Birth Cohort at 30-Year-Old Follow-up. | Kisely S et al. | — | 2021 | → |
| Child Maltreatment, Early Adult Substance Use, and Mediation by Adolescent Behavior Problems. | Dubowitz H et al. | — | 2021 | → |
| Mediating Factors Explaining the Association Between Sexual Minority Status and Dating Violence. | Martin-Storey A et al. | — | 2021 | → |
| The Mediating Role of Distress Tolerance in the Relationship Between Childhood Maltreatment and Mental Health Outcomes Among University Students. | Robinson M et al. | — | 2021 | → |
| Use of pharmacotherapy for alcohol use disorder in Manitoba, Canada: A whole-population cohort study. | Konrad G et al. | — | 2021 | → |
| Childhood maltreatment, motives to drink and alcohol-related problems in young adulthood. | Shin SH et al. | — | 2020 | → |
| The Type and Timing of Child Maltreatment as Predictors of Adolescent Cigarette Smoking Trajectories. | Yoon S et al. | — | 2020 | → |
| Adverse Childhood Experiences and E-Cigarette Use During Young Adulthood. | Shin SH et al. | — | 2019 | → |
| Adverse Childhood Experiences and the Presence of Cancer Risk Factors in Adulthood: A Scoping Review of the Literature From 2005 to 2015. | Ports KA et al. | — | 2019 | → |
| A life course approach to total tooth loss: Testing the sensitive period, accumulation, and social mobility models in the Health and Retirement Study. | Lee H | — | 2019 | → |
| Child maltreatment and the development of substance use and disorder. | Cicchetti D et al. | — | 2019 | → |
| Early childhood maltreatment experience and later sexual behavior in Brazilian adults undergoing treatment for substance dependence. | Diehl A et al. | — | 2019 | → |
| History of childhood abuse is associated with less positive treatment outcomes in socially stable women with alcohol use disorder. | Schückher F et al. | — | 2019 | → |
| Impact of Alcohol Outlet Density on Reported Cases of Child Maltreatment in Japan: Fixed Effects Analysis. | Koyama Y et al. | — | 2019 | → |
| Effect of childhood adversities on alcohol problems is mainly mediated by depression. | Salokangas RKR et al. | — | 2018 | → |
| Impact of early life adversity on the stress biobehavioral response during nicotine withdrawal. | al'Absi M et al. | — | 2018 | → |
| Major life events and risk of alcohol use disorders: a prospective cohort study. | Just-Østergaard E et al. | — | 2018 | → |
| Stressful life events influence transitions among latent classes of alcohol use. | Hoyland MA et al. | — | 2018 | → |
| Childhood trauma exposure in substance use disorder patients with and without ADHD. | Konstenius M et al. | — | 2017 | → |
| Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study. | Bucholz KK et al. | — | 2017 | → |
| Early life adversity influences stress response association with smoking relapse. | al'Absi M et al. | — | 2017 | → |
| From child maltreatment to emerging adult problem drinking: Identification of a multilevel internalizing pathway among African American youth. | Handley ED et al. | — | 2017 | → |
| [Out of addictions: Alcohol, or alcohol to alcohol]. | Simmat-Durand L et al. | — | 2017 | → |
| Predicting the onset of hazardous alcohol drinking in primary care: development and validation of a simple risk algorithm. | Bellón JÁ et al. | — | 2017 | → |
| Socioeconomic Inequality in Concurrent Tobacco and Alcohol Consumption | Intarut N et al. | — | 2017 | → |
| Stress-related salivary alpha-amylase (sAA) activity in alcohol dependent patients with and without a history of childhood maltreatment. | Muehlhan M et al. | — | 2017 | → |
| The places parents go: understanding the breadth, scope, and experiences of activity spaces for parents. | Wolf JP et al. | — | 2017 | → |
| Childhood maltreatment, personality disorders and 3-year persistence of adult alcohol and nicotine dependence in a national sample. | Elliott JC et al. | — | 2016 | → |
| Childhood Trauma and Illicit Drug Use in Adolescence: A Population-Based National Comorbidity Survey Replication-Adolescent Supplement Study. | Carliner H et al. | — | 2016 | → |
| Life adversity is associated with smoking relapse after a quit attempt. | Lemieux A et al. | — | 2016 | → |
| Perceived parental care during childhood, ACTH, cortisol and nicotine dependence in the adult. | Gerra G et al. | — | 2016 | → |
| Testing a Social Mechanism: Does Alcohol Outlet Density Moderate the Relationship Between Levels of Alcohol Use and Child Physical Abuse? | Freisthler B et al. | — | 2016 | → |
| The natural history of substance use disorders. | Sarvet AL et al. | — | 2016 | → |
| Understanding the Roles of Context, Frequency, and Quantity of Alcohol Consumption in Child Physical Abuse: Risks for Mothers and Fathers. | Wolf JP et al. | — | 2016 | → |
| Adverse childhood experiences and geriatric depression: results from the 2010 BRFSS. | Ege MA et al. | — | 2015 | → |
| Cognitive manifestations of drinking-smoking associations: preliminary findings with a cross-primed Stroop task. | Oliver JA et al. | — | 2015 | → |
| Epidemiological Studies of Substance Dependence and Abuse in Adults. | Delker E et al. | — | 2015 | → |
| Impact of Exposure to Childhood Maltreatment on Transitions to Alcohol Dependence in Women and Men. | Oberleitner LM et al. | — | 2015 | → |
| The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 and 2: review and summary of findings. | Hasin DS et al. | — | 2015 | → |
| Tobacco Use among Foster Youth: Evidence of Health Disparities. | Braciszewski JM et al. | — | 2015 | → |