The genomic psychiatry cohort: partners in discovery.
- Authors
- Pato, Michele T; Sobell, Janet L; Medeiros, Helena; Abbott, Colony; Sklar, Brooke M; Buckley, Peter F; Bromet, Evelyn J; Escamilla, Michael A; Fanous, Ayman H; Lehrer, Douglas S; Macciardi, Fabio; Malaspina, Dolores; McCarroll, Steve A; Marder, Stephen R; Moran, Jennifer; Morley, Christopher P; Nicolini, Humberto; Perkins, Diana O; Purcell, Shaun M; Rapaport, Mark H; Sklar, Pamela; Smoller, Jordan W; Knowles, James A; Genomic Psychiatry Cohort Consortium; Pato, Carlos N
- Year
- 2013
- Journal
- American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
- PMID
- 23650244
- DOI
- 10.1002/ajmg.b.32160
- PMCID
- PMC3729260
The Genomic Psychiatry Cohort (GPC) is a longitudinal resource designed to provide the necessary population-based sample for large-scale genomic studies, studies focusing on Research Domain Criteria (RDoC) and/or other alternate phenotype constructs, clinical and interventional studies, nested case-control studies, long-term disease course studies, and genomic variant-to-phenotype studies. We provide and will continue to encourage access to the GPC as an international resource. DNA and other biological samples and diagnostic data are available through the National Institute of Mental Health (NIMH) Repository. After appropriate review and approval by an advisory board, investigators are able to collaborate in, propose, and co-lead studies involving cohort participants.
No figures extracted from this document.
No entities extracted from this document yet.
No uploaded files.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Comorbidity of severe psychotic disorders with measures of substance use. | 2014 | 24382686 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Understanding and characterizing the higher rates of medical comorbidities in serious mental illness. | Farooqui M et al. | — | 2026 | → |
| Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia. | Li R et al. | — | 2026 | → |
| African Americans' lived experiences with serious mental illness and cardiovascular disease: a syndemic perspective. | Salisu M et al. | — | 2025 | → |
| Association between the methyl-CpG-binding domain protein 5 gene and depressive symptoms in a Mexican population: results from the MxGDAR/Encodat cohort. | Sanabrais-Jiménez MA et al. | — | 2025 | → |
| Obsessive-compulsive disorder with hoarding behavior: unravelling key differences. | de Mattos CN et al. | — | 2025 | → |
| Psychometric properties of the Spanish Yale-Brown Obsessive-Compulsive Scale - Second Edition. | Storch EA et al. | — | 2025 | → |
| Risk of Cardiovascular Disease Associated with Serious Mental Illness among People of African Ancestry. | Salisu M et al. | — | 2025 | → |
| Where is mania in the meta-structure of psychopathology? | Ruggero CJ et al. | — | 2025 | → |
| Latin American Trans-ancestry INitiative for OCD genomics (LATINO): Study protocol. | Crowley JJ et al. | — | 2024 | → |
| Phenotype harmonization and analysis for The Populations Underrepresented in Mental illness Association Studies (the PUMAS Project) | Ramirez-Diaz AM et al. | — | 2024 | — |
| Baroreflex sensitivity is associated with markers of hippocampal gliosis and dysmyelination in patients with psychosis. | Mueller B et al. | — | 2023 | → |
| Genetic substrates of bipolar disorder risk in Latino families. | Escamilla M et al. | — | 2023 | → |
| Racial differences in the major clinical symptom domains of bipolar disorder. | Li K et al. | — | 2023 | → |
| Risk for alcohol use problems in severe mental illness: Interactions with sex and racial/ethnic minority status. | Levit JD et al. | — | 2023 | → |
| Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan. | Valkovskaya M et al. | — | 2023 | → |
| The Prevalence of Symptomatology and Risk Factors in Mental Health in Mexico: The 2016-17 ENCODAT Cohort. | Medina-Mora ME et al. | — | 2023 | → |
| Traumatic events in childhood and adulthood in a diverse-ancestry sample and their role in bipolar disorder. | Chen Q et al. | — | 2023 | → |
| An integrative study of the microbiome gut-brain-axis and hippocampal inflammation in psychosis: Persistent effects from mode of birth. | Joe P et al. | — | 2022 | → |
| Development of the Thought Disorder Measure for the Hierarchical Taxonomy of Psychopathology. | Cicero DC et al. | — | 2022 | → |
| Extent to which array genotyping and imputation with large reference panels approximate deep whole-genome sequencing. | Hanks SC et al. | — | 2022 | → |
| Genome-Wide Analysis of Disordered Eating Behavior in the Mexican Population. | Martínez-Magaña JJ et al. | — | 2022 | → |
| Polygenic risk scores for predicting outcomes and treatment response in psychiatry: hope or hype? | Fusar-Poli L et al. | — | 2022 | → |
| Whole-genome analysis of human embryonic stem cells enables rational line selection based on genetic variation. | Merkle FT et al. | — | 2022 | → |
| Cannabis Use in People With Obsessive-Compulsive Symptomatology: Results From a Mexican Epidemiological Sample. | Nicolini H et al. | — | 2021 | → |
| Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans. | Bigdeli TB et al. | — | 2021 | → |
| Genome-wide association study of psychiatric and substance use comorbidity in Mexican individuals. | Martínez-Magaña JJ et al. | — | 2021 | → |
| High-impact rare genetic variants in severe schizophrenia. | Zoghbi AW et al. | — | 2021 | → |
| Prognostic value of polygenic risk scores for adults with psychosis. | Landi I et al. | — | 2021 | → |
| The Impact of Ethnicity and Genetic Ancestry on Disease Prevalence and Risk in Colombia. | Chande AT et al. | — | 2021 | → |
| The neurocognitive and functional profile of schizophrenia in a genetically homogenous European sample. | da Motta C et al. | — | 2021 | → |
| What Have We Learned About the Genetics of Obsessive-Compulsive and Related Disorders in Recent Years? | Mattheisen M et al. | — | 2021 | → |
| Challenges and Opportunities to Meet the Mental Health Needs of Underserved and Disenfranchised Populations in the United States. | Mongelli F et al. | — | 2020 | → |
| Complement genes contribute sex-biased vulnerability in diverse disorders. | Kamitaki N et al. | — | 2020 | → |
| Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia. | Evgrafov OV et al. | — | 2020 | → |
| Greater history of traumatic event exposure and PTSD associated with comorbid body dysmorphic disorder in a large OCD cohort. | Valderrama J et al. | — | 2020 | → |
| The effect of LRRK2 loss-of-function variants in humans. | Whiffin N et al. | — | 2020 | → |
| The Identification of Admixture Patterns Could Refine Pharmacogenetic Counseling: Analysis of a Population-Based Sample in Mexico. | Martínez-Magaña JJ et al. | — | 2020 | → |
| Apolipoprotein E-ε4 allele predicts escalation of psychotic symptoms in late adulthood. | Jonas K et al. | — | 2019 | → |
| Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases. | Charney AW et al. | — | 2019 | → |
| Early processing (N170) of infant faces in mothers of children with autism spectrum disorder and its association with maternal sensitivity. | Márquez C et al. | — | 2019 | → |
| Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts. | Zhang X et al. | — | 2019 | → |
| International Society of Psychiatric Genetics Ethics Committee: Issues facing us. | Lázaro-Muñoz G et al. | — | 2019 | → |
| Schizophrenia polygenic risk score and 20-year course of illness in psychotic disorders. | Jonas KG et al. | — | 2019 | → |
| A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica. | Estrada K et al. | — | 2018 | → |
| Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans. | Carlson J et al. | — | 2018 | → |
| Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis. | International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS) | — | 2018 | → |
| Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. | Charney AW et al. | — | 2017 | → |
| Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome. | Huang AY et al. | — | 2017 | → |
| Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study. | Montano C et al. | — | 2016 | → |
| LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family. | Guffanti G et al. | — | 2016 | → |
| Nicotine dependence and psychosis in Bipolar disorder and Schizoaffective disorder, Bipolar type. | Estrada E et al. | — | 2016 | → |
| Paternal age effect: Replication in schizophrenia with intriguing dissociation between bipolar with and without psychosis. | Lehrer DS et al. | — | 2016 | → |
| Substance use associated with short sleep duration in patients with schizophrenia or schizoaffective disorder. | Tang VK et al. | — | 2016 | → |
| Symptoms of psychosis in schizophrenia, schizoaffective disorder, and bipolar disorder: A comparison of African Americans and Caucasians in the Genomic Psychiatry Cohort. | Perlman G et al. | — | 2016 | → |
| Traumatic brain injury and bipolar psychosis in the Genomic Psychiatry Cohort. | Cieslak K et al. | — | 2016 | → |
| An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders. | Kohane IS | — | 2015 | → |
| A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. | Duan J et al. | — | 2014 | → |
| CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1. | Rees E et al. | — | 2014 | → |
| Comorbidity of severe psychotic disorders with measures of substance use. | Hartz SM et al. | — | 2014 | → |