A new multipoint method for genome-wide association studies by imputation of genotypes.
paper
Cited
Public
Unavailable
- Authors
- Marchini, Jonathan; Howie, Bryan; Myers, Simon; McVean, Gil; Donnelly, Peter
- Year
- 2007
- Journal
- Nature genetics
- PMID
- 17572673
- DOI
- 10.1038/ng2088
Genome-wide association studies are set to become the method of choice for uncovering the genetic basis of human diseases. A central challenge in this area is the development of powerful multipoint methods that can detect causal variants that have not been directly genotyped. We propose a coherent analysis framework that treats the problem as one involving missing or uncertain genotypes. Central to our approach is a model-based imputation method for inferring genotypes at observed or unobserved SNPs, leading to improved power over existing methods for multipoint association mapping. Using real genome-wide association study data, we show that our approach (i) is accurate and well calibrated, (ii) provides detailed views of associated regions that facilitate follow-up studies and (iii) can be used to validate and correct data at genotyped markers. A notable future use of our method will be to boost power by combining data from genome-wide scans that use different SNP sets.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| A genome-wide association meta-analysis of cholesterol synthesis intermediates identifies three associations for lanosterol. | FΓΆrster F et al. | β | 2026 | β |
| Bayesian variable selection for genome-wide association study of grain traits in rice. | Basu R et al. | β | 2026 | β |
| Bioinformatics Approaches in Noncoding RNAs Research. | Khan F et al. | β | 2026 | β |
| Development and Validation of a Genome-Wide Association Study Based Polygenic Risk Score for Prostate Cancer in an Asian Population. | Geng JH et al. | β | 2026 | β |
| Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation. | Dekkers KF et al. | β | 2026 | β |
| Genotype-driven variations in lncRNA expression underlie predisposition to high-grade serous ovarian cancer. | Lu M et al. | β | 2026 | β |
| Identification of a genetic risk factor for metformin-induced vitamin B<sub>12</sub> deficiency. | Baldwin FD et al. | β | 2026 | β |
| RAB3GAP2 is a regulator of skeletal muscle endothelial cell proliferation and associated with capillary-to-fiber ratio. | StrΓΆm K et al. | β | 2026 | β |
| Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33. | Connelly KE et al. | β | 2025 | β |
| A multi-omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data. | GineviΔienΔ V et al. | β | 2025 | β |
| An updated Pig Haplotype Reference Panel (PHARP 4.0) comprising 13,298 haplotypes. | Wang Q et al. | β | 2025 | β |
| Artificial Intelligence and Computational Biology in Gene Therapy: A Review. | Danaeifar M et al. | β | 2025 | β |
| Conservation and lability within the structure of mandibular integration in βold endemicβ Australian rodents | Ng RY | β | 2025 | β |
| Contrasting genetic predisposition and diagnosis in psychiatric disorders: A multi-omic single-nucleus analysis of the human OFC. | Gerstner N et al. | β | 2025 | β |
| COPD-associated proteins as biomarkers and drug targets: Insights from genetic and proteomic analyses. | Lin X et al. | β | 2025 | β |
| Data simulation to optimize frameworks for genome-wide association studies in diverse populations. | Mugo JW et al. | β | 2025 | β |
| Deep analysis of the major histocompatibility complex genetic associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Control in AIDS. | Rahmouni M et al. | β | 2025 | β |
| Development and validation of a polygenic risk score for height in a Greek cohort: Association with blood pressure measurements. | Kalafati IP et al. | β | 2025 | β |
| EasyOmics: A graphical interface for population-scale omics data association, integration, and visualization. | Han Y et al. | β | 2025 | β |
| EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis. | Wang L et al. | β | 2025 | β |
| Evaluation of polygenic scores for hypertrophic cardiomyopathy in the general population and across clinical settings. | Zheng SL et al. | β | 2025 | β |
| Exploring the contribution of genetic variants to high sunitinib exposure in patients with cancer. | Giraud EL et al. | β | 2025 | β |
| Fine-mapping the CYP2A6 regional association with nicotine metabolism among African American smokers. | Pouget JG et al. | β | 2025 | β |
| Genetic Predisposition to Hippocampal Atrophy and Risk of Amnestic Mild Cognitive Impairment and Alzheimer's Dementia. | Liampas I et al. | β | 2025 | β |
| Genetic PrΞΏpensity for Different Aspects of Dementia Pathology and Cognitive Decline in a Community Elderly Population. | Sampatakakis SN et al. | β | 2025 | β |
| Genome-wide analysis identifies susceptibility loci for heart failure and nonischemic cardiomyopathy subtype in the East Asian populations. | Han Y et al. | β | 2025 | β |
| Genome-wide association analysis revealed novel candidate genes for body measurement traits in indigenous Gudali and crossbred Simgud in Cameroon. | Matenchi YP et al. | β | 2025 | β |
| Genome-wide association study of Asian women identifies putative mammographic density-associated loci. | Mariapun S et al. | β | 2025 | β |
| Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci. | Cole JB et al. | β | 2025 | β |
| Identification of a VHL germline deletion in a family with Von Hippel-Lindau syndrome using MLPA-NGS. | Yang Y et al. | β | 2025 | β |
| Identification of gene-sun exposure interactions of GWAS-identified variants in perceived facial aging progression. | Obry L et al. | β | 2025 | β |
| Impact of placental and peripheral blood DNA methylation on celiac disease susceptibility. | Hernangomez-Laderas A et al. | β | 2025 | β |
| Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants. | Liu H et al. | β | 2025 | β |
| Machine learning solutions for integrating partially overlapping genetic datasets and modelling host-endophyte effects in ryegrass (<i>Lolium</i>) dry matter yield estimation. | Zhu J et al. | β | 2025 | β |
| Missing genotype imputation in non-model species using self-organizing maps. | Mora-MΓ‘rquez F et al. | β | 2025 | β |
| Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease. | Rajabli F et al. | β | 2025 | β |
| Novel genetic variants associated with stable isotope-based vitamin B<sub>12</sub> bioavailability measurements in healthy Indian adults. | Sivadas A et al. | β | 2025 | β |
| Proteogenomic analysis reveals Arp 2/3 complex as a common molecular mechanism in high risk pancreatic cysts and pancreatic cancer. | Mahmud AKMF et al. | β | 2025 | β |
| Recent Statistical Innovations in Human Genetics. | Balding DJ et al. | β | 2025 | β |
| SURFBAT: a surrogate family based association test building on large imputation reference panels. | Herzig AF et al. | β | 2025 | β |
| The Intersection of Genetics and Neuroimaging: A Systematic Review of Imaging Genetics in Neurological Disease for Personalized Treatment. | Mashhour MA et al. | β | 2025 | β |
| The NHGRI-EBI GWAS Catalog: standards for reusability, sustainability and diversity. | Cerezo M et al. | β | 2025 | β |
| The role of body image dissatisfaction in the relationship between body size and disordered eating and self-harm: complimentary Mendelian randomization and mediation analyses. | Power GM et al. | β | 2025 | β |
| X-chromosome-wide association study for Alzheimer's disease. | Le Borgne J et al. | β | 2025 | β |
| A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren's disease. | Riesmeijer SA et al. | β | 2024 | β |
| A Genome-Wide Association Study of Endoxifen Serum Concentrations and Adjuvant Tamoxifen Efficacy in Early-Stage Breast Cancer Patients. | Sanchez-Spitman AB et al. | β | 2024 | β |
| APOE epsilon variants and composite risk of dementia, disability, and death in the health and retirement study. | Clocchiatti-Tuozzo S et al. | β | 2024 | β |
| Association of CYP2D6 and CYP2C19 metabolizer status with switching and discontinuing antidepressant drugs: an exploratory study. | Brouwer JMJL et al. | β | 2024 | β |
| Associations between Disc Hemorrhage and Primary Open-Angle Glaucoma Based on Genome-Wide Association and Mendelian Randomization Analyses. | Seo JH et al. | β | 2024 | β |
| Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes. | Yan D et al. | β | 2024 | β |
| Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry. | Burns K et al. | β | 2024 | β |
| Casual relationships between circulating metabolites and rheumatoid arthritis: A mendelian randomization study. | An G et al. | β | 2024 | β |
| Cerebral Amyloidosis in Individuals with Subjective Cognitive Decline: From Genetic Predisposition to Actual Cerebrospinal Fluid Measurements. | Sampatakakis SN et al. | β | 2024 | β |
| Deciphering the genetics and mechanisms of predisposition to multiple myeloma. | Went M et al. | β | 2024 | β |
| Development and evaluation of a polygenic risk score for lung cancer in never-smoking women: A large-scale prospective Chinese cohort study. | Wei X et al. | β | 2024 | β |
| Evaluation of penalized and machine learning methods for asthma disease prediction in the Korean Genome and Epidemiology Study (KoGES). | Choi Y et al. | β | 2024 | β |
| Exact Decoding of a Sequentially Markov Coalescent Model in Genetics. | Ki C et al. | β | 2024 | β |
| Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry. | Ray NR et al. | β | 2024 | β |
| Forensic height estimation using polygenic score in Korean population. | Cho HW et al. | β | 2024 | β |
| From GWASs toward Mechanistic Understanding with Case Studies in Dermatogenetics. | Shen S et al. | β | 2024 | β |
| Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people. | Koyanagi YN et al. | β | 2024 | β |
| Genetic mapping across autoimmune diseases reveals shared associations and mechanisms. | Lincoln MR et al. | β | 2024 | β |
| Genetic Predisposition for White Matter Hyperintensities and Risk of Mild Cognitive Impairment and Alzheimer's Disease: Results from the HELIAD Study. | Sampatakakis SN et al. | β | 2024 | β |
| Genetic risk for Alzheimer's disease and adherence to the Mediterranean diet: results from the HELIAD study. | Mamalaki E et al. | β | 2024 | β |
| Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci. | Lori A et al. | β | 2024 | β |
| Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes. | Farrell K et al. | β | 2024 | β |
| Genome-Wide Analyses of Vocabulary Size in Infancy and Toddlerhood: Associations With Attention-Deficit/Hyperactivity Disorder, Literacy, and Cognition-Related Traits. | Verhoef E et al. | β | 2024 | β |
| Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. | Keaton JM et al. | β | 2024 | β |
| Genome-wide association and polygenic risk score estimation of type 2 diabetes mellitus in Kinh Vietnamese-A pilot study. | Mai TP et al. | β | 2024 | β |
| Genome-wide association reveals a locus in neuregulin 3 associated with gabapentin efficacy in women with chronic pelvic pain. | Mackenzie SC et al. | β | 2024 | β |
| Genome-wide association study identifies high-impact susceptibility loci for HCC in North America. | Hassan MM et al. | β | 2024 | β |
| Genome-wide association study of hospitalized patients and acute kidney injury. | Siew ED et al. | β | 2024 | β |
| Genome-Wide Genetic Associations Prioritize Evaluation of Causal Mechanisms of Atherosclerotic Disease Risk. | Quertermous T et al. | β | 2024 | β |
| Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125β393 Participants. | Young WJ et al. | β | 2024 | β |
| Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas. | Hughes O et al. | β | 2024 | β |
| Identification of interactions between genetic risk scores and dietary patterns for personalized prevention of kidney dysfunction in a population-based cohort. | Jang MJ et al. | β | 2024 | β |
| Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation. | ThΓ©riault S et al. | β | 2024 | β |
| Mitochondrial Variation in Anopheles gambiae and Anopheles coluzzii: Phylogeographic Legacy and Mitonuclear Associations With Metabolic Resistance to Pathogens and Insecticides. | Amaya Romero JE et al. | β | 2024 | β |
| Nightmares share genetic risk factors with sleep and psychiatric traits. | Ollila HM et al. | β | 2024 | β |
| Novel genetic loci of inhibitory control in ADHD and healthy children and genetic correlations with ADHD. | Pang T et al. | β | 2024 | β |
| Parkinson Disease Genetics Extended to African and Hispanic Ancestries in the VA Million Veteran Program. | Pankratz N et al. | β | 2024 | β |
| Reviewing the essential roles of remote phenotyping, GWAS and explainable AI in practical marker-assisted selection for drought-tolerant winter wheat breeding. | Chang-Brahim I et al. | β | 2024 | β |
| Single-nucleus transcriptomic profiling of human orbitofrontal cortex reveals convergent effects of aging and psychiatric disease. | FrΓΆhlich AS et al. | β | 2024 | β |
| Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci. | Carnes MU et al. | β | 2024 | β |
| The importance of genotyping within the climate-smart plant breeding value chain - integrative tools for genetic enhancement programs. | Garcia-Oliveira AL et al. | β | 2024 | β |
| The transition from genomics to phenomics in personalized population health. | Yurkovich JT et al. | β | 2024 | β |
| Whole genome sequencing of three native chicken varieties (Common Deshi, Hilly and Naked Neck) of Bangladesh. | Rabbani MAG et al. | β | 2024 | β |
| Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease. | Xicota L et al. | β | 2024 | β |
| 10Β Years of GWAS in intraocular pressure. | Gao XR et al. | β | 2023 | β |
| Accurate rare variant phasing of whole-genome and whole-exome sequencing data in the UK Biobank. | Hofmeister RJ et al. | β | 2023 | β |
| A Genome-Wide Association Study of Metabolic Syndrome in the Taiwanese Population. | Ho CY et al. | β | 2023 | β |
| Ancestral diversity in lipoprotein(a) studies helps address evidence gaps. | Lee MP et al. | β | 2023 | β |
| An empirical investigation into the impact of winner's curse on estimates from Mendelian randomization. | Jiang T et al. | β | 2023 | β |
| A novel polygenic risk score improves prognostic prediction of heart failure with preserved ejection fraction in the Chinese Han population. | Han Y et al. | β | 2023 | β |
| Case-case genome-wide association analysis identifying genetic loci with divergent effects on Crohn's disease and ulcerative colitis. | Jung S et al. | β | 2023 | β |
| Comparison of multiple imputation and other methods for the analysis of imputed genotypes. | Auer PL et al. | β | 2023 | β |
| Contribution of <i>ADD3</i> and the HLA Genes to Biliary Atresia Risk in Chinese. | Cui MM et al. | β | 2023 | β |
| Decreased FAM13B Expression Increases Atrial Fibrillation SusceptibilityΒ by Regulating Sodium Current and CalciumΒ Handling. | Tchou G et al. | β | 2023 | β |
| Deep learning-based phenotype imputation on population-scale biobank data increases genetic discoveries. | An U et al. | β | 2023 | β |
| Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing. | Cui L et al. | β | 2023 | β |
| eaQTLdb: An atlas of enhancer activity quantitative trait loci across cancer types. | Yuan J et al. | β | 2023 | β |
| Effect of genetic variants in <i>UBE2O</i> and <i>TPK1</i> on facial morphology of Koreans. | Cho HW et al. | β | 2023 | β |
| Evaluating the genetic interaction effects of gut microbiome and diet on the risk of neuroticism in the UK Biobank cohort. | He D et al. | β | 2023 | β |
| Evaluation of optimal methods and ancestries for calculating polygenic risk scores in East Asian population. | Kim DJ et al. | β | 2023 | β |
| Gene-Folic Acid Interactions and Risk of Conotruncal Heart Defects: Results from the National Birth Defects Prevention Study. | Webber DM et al. | β | 2023 | β |
| geneHapR: an R package for gene haplotypic statistics and visualization. | Zhang R et al. | β | 2023 | β |
| Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results. | Baron C et al. | β | 2023 | β |
| Genetics of osteonecrosis in children and adults with systemic lupus erythematosus. | Webber D et al. | β | 2023 | β |
| Genetics of Plasma Bilirubin and Associations between Bilirubin and Cardiometabolic Risk Profiles in Danish Children and Adolescents. | Ullah A et al. | β | 2023 | β |
| Genome-wide aggregated trans-effects on risk of type 1 diabetes: A test of the "omnigenic" sparse effector hypothesis of complex trait genetics. | Iakovliev A et al. | β | 2023 | β |
| Genome-Wide Association Studies of Diarrhea Frequency and Duration in the First Year of Life in Bangladeshi Infants. | Munday RM et al. | β | 2023 | β |
| Genome-Wide Association Study of Blood Mercury in European Pregnant Women and Children. | Dack K et al. | β | 2023 | β |
| Genome-wide Association Study of Methotrexate-Induced Liver Injury in Rheumatoid Arthritis Patients. | Eektimmerman F et al. | β | 2023 | β |
| Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator. | Cardinale CJ et al. | β | 2023 | β |
| Genome-wide genotyping data renew knowledge on genetic diversity of a worldwide alfalfa collection and give insights on genetic control of phenology traits. | PΓ©gard M et al. | β | 2023 | β |
| Genotype imputation accuracy and the quality metrics of the minor ancestry in multi-ancestry reference panels. | Shi M et al. | β | 2023 | β |
| GWAs Identify DNA Variants Influencing Eyebrow Thickness Variation in Europeans and Across Continental Populations. | Peng F et al. | β | 2023 | β |
| GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level. | SchrΓΆder J et al. | β | 2023 | β |
| Identification of genetic variants associated with diabetic kidney disease in multiple Korean cohorts via a genome-wide association study mega-analysis. | Jin H et al. | β | 2023 | β |
| Identification of Novel Genetic Risk Factors for Focal Segmental Glomerulosclerosis in Children: Results From the Chronic Kidney Disease in Children (CKiD) Cohort. | Durand A et al. | β | 2023 | β |
| Identification of PCSK9-like human gene knockouts using metabolomics, proteomics, and whole-genome sequencing in a consanguineous population. | Belkadi A et al. | β | 2023 | β |
| Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes. | McAllan L et al. | β | 2023 | β |
| Large-scale meta-genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types. | Naderi E et al. | β | 2023 | β |
| Low and high serum IgG associates with respiratory infections in a young and working age population. | Holma P et al. | β | 2023 | β |
| Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci. | Pasanen A et al. | β | 2023 | β |
| Natural variation of codon repeats in <i>COLD11</i> endows rice with chilling resilience. | Li Z et al. | β | 2023 | β |
| On the origin and structure of haplotype blocks. | Shipilina D et al. | β | 2023 | β |
| Plasma Concentrations of Calcium and Risk of Alzheimer Disease-Observational and Genetic Studies. | Thomassen JQ et al. | β | 2023 | β |
| Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study. | Ho PJ et al. | β | 2023 | β |
| Prevalence of non-alcoholic fatty liver in the general Dutch population and in groups at increased risk. | Alblas G et al. | β | 2023 | β |
| Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis. | Wang B et al. | β | 2023 | β |
| Re-Evaluation of Genotyping Methodologies in Cattle: The Proficiency of Imputation. | Gershoni M et al. | β | 2023 | β |
| Repeat polymorphisms underlie top genetic risk loci for glaucoma and colorectal cancer. | Mukamel RE et al. | β | 2023 | β |
| Robust Bioinformatics Approaches Result in the First Polygenic Risk Score for BMI in Greek Adults. | Kafyra M et al. | β | 2023 | β |
| Secretory leukocyte protease inhibitor and risk of heart failure in the Multi-Ethnic Study of Atherosclerosis. | Sawicki KT et al. | β | 2023 | β |
| Sex bias in celiac disease: XWAS and monocyte eQTLs in women identify TMEM187 as a functional candidate gene. | Hernangomez-Laderas A et al. | β | 2023 | β |
| SNPtotree-Resolving the Phylogeny of SNPs on Non-Recombining DNA. | KΓΆksal Z et al. | β | 2023 | β |
| Summary statistics-based association test for identifying the pleiotropic effects with set of genetic variants. | Bu D et al. | β | 2023 | β |
| Systematic evaluation of narrow-sense validity of polygenic risk score for prostate cancer in a Chinese prostate biopsy cohort. | Wu Y et al. | β | 2023 | β |
| Testing for pharmacogenomic predictors of ppRNFL thinning in individuals exposed to vigabatrin. | Boothman I et al. | β | 2023 | β |
| The genetic etiology of periodic limb movement in sleep. | Edelson JL et al. | β | 2023 | β |
| The <i>HLA-B*57:01</i> allele corresponds to a very large <i>MHC</i> haploblock likely explaining its massive effect for HIV-1 elite control. | Rahmouni M et al. | β | 2023 | β |
| The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes. | Huerta-Chagoya A et al. | β | 2023 | β |
| The solution surface of the Li-Stephens haplotype copying model. | Jin Y et al. | β | 2023 | β |
| Two-Sample Mendelian Randomization detects bidirectional causality between gut microbiota and celiac disease in individuals with high genetic risk. | GonzΓ‘lez-GarcΓa BP et al. | β | 2023 | β |
| A Genome-Wide Association Study of Genetic Variants of Apolipoprotein A1 Levels and Their Association with Vitamin D in Korean Cohorts. | Lee Y et al. | β | 2022 | β |
| A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis. | Schack LMH et al. | β | 2022 | β |
| A genome-wide association study with tissue transcriptomics identifies genetic drivers for classic bladder exstrophy. | Mingardo E et al. | β | 2022 | β |
| A joint use of pooling and imputation for genotyping SNPs. | Clouard C et al. | β | 2022 | β |
| An updated view of the pathogenesis of steroid-sensitive nephrotic syndrome. | Horinouchi T et al. | β | 2022 | β |
| A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam. | Campbell C et al. | β | 2022 | β |
| A Pipeline for Phasing and Genotype Imputation on Mixed Human Data (Parents-Offspring Trios and Unrelated Subjects) by Reviewing Current Methods and Software. | Baldrighi GN et al. | β | 2022 | β |
| Assessing accuracy of genotype imputation in the Afrikaner and Brahman cattle breeds of South Africa. | Mdyogolo S et al. | β | 2022 | β |
| Association between gut microbiota and longevity: a genetic correlation and mendelian randomization study. | He D et al. | β | 2022 | β |
| Association between <i>IKBKAP</i> polymorphisms and Hirschsprung's disease susceptibility in Chinese children. | Wang N et al. | β | 2022 | β |
| Associations between polygenic risk, negative symptoms, and functional connectome topology during a working memory task in early-onset schizophrenia. | Deng M et al. | β | 2022 | β |
| Association with HLA-DRΞ²1 position 37 distinguishes juvenile dermatomyositis from adult-onset myositis. | Deakin CT et al. | β | 2022 | β |
| A systems immunology approach to investigate cytokine responses to viruses and bacteria and their association with disease. | Lin L et al. | β | 2022 | β |
| Best practices for analyzing imputed genotypes from low-pass sequencing in dogs. | Buckley RM et al. | β | 2022 | β |
| Blood copper and risk of cardiometabolic diseases: a Mendelian randomization study. | JΓ€ger S et al. | β | 2022 | β |
| Canary: an automated tool for the conversion of MaCH imputed dosage files to PLINK files. | Bennett AN et al. | β | 2022 | β |
| COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection. | Wang Y et al. | β | 2022 | β |
| Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology. | Wittenbecher C et al. | β | 2022 | β |
| Donor and recipient polygenic risk scores influence the risk of post-transplant diabetes. | Shaked A et al. | β | 2022 | β |
| Efficient approaches for large-scale GWAS with genotype uncertainty. | JΓΈrsboe E et al. | β | 2022 | β |
| Enhancer-promoter interaction maps provide insights into skeletal muscle-related traits in pig genome. | Li J et al. | β | 2022 | β |
| Extended kinship analysis of historical remains using SNP capture. | Gorden EM et al. | β | 2022 | β |
| Genetic Analysis in African American Children Supports Ancestry-Specific Neuroblastoma Susceptibility. | Testori A et al. | β | 2022 | β |
| Genetic and environmental etiology of drinking motives in college students. | Savage JE et al. | β | 2022 | β |
| Genetic association of primary nonresponse to anti-TNFΞ± therapy in patients with inflammatory bowel disease. | De T et al. | β | 2022 | β |
| Genetic associations at regulatory phenotypes improve fine-mapping of causal variants for 12 immune-mediated diseases. | Kundu K et al. | β | 2022 | β |
| Genetic associations with healthy ageing among Chinese adults. | Chang X et al. | β | 2022 | β |
| Genetic trade-offs between complex diseases and longevity. | Hu D et al. | β | 2022 | β |
| Genetic Variants Relate to Fasting Plasma Glucose, 2-Hour Postprandial Glucose, Glycosylated Hemoglobin, and BMI in Prediabetes. | Lin L et al. | β | 2022 | β |
| Genome and transcriptome profiling of spontaneous preterm birth phenotypes. | Gupta JK et al. | β | 2022 | β |
| Genome-Wide Association Study for eGFR in a Taiwanese Population. | Chen YC et al. | β | 2022 | β |
| Genome-wide association study identifies genetic risk loci for adiposity in a Taiwanese population. | Wong HS et al. | β | 2022 | β |
| Genome-wide association study meta-analysis identifies three novel loci for circulating anti-MΓΌllerian hormone levels in women. | Verdiesen RMG et al. | β | 2022 | β |
| Genome-Wide Association Study of Campylobacter<i>-</i>Positive Diarrhea Identifies Genes Involved in Toxin Processing and Inflammatory Response. | Munday RM et al. | β | 2022 | β |
| Genome-wide association study of idiopathic hypersomnia in a Japanese population. | Tanida K et al. | β | 2022 | β |
| Genome-wide association study of leprosy in Malawi and Mali. | Gilchrist JJ et al. | β | 2022 | β |
| Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse. | Roselli C et al. | β | 2022 | β |
| Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. | Czamara D et al. | β | 2022 | β |
| Genome-Wide Integration of Genetic and Genomic Studies of Atopic Dermatitis: Insights into Genetic Architecture and Pathogenesis. | Chen Y et al. | β | 2022 | β |
| Genome-Wide Meta-Analysis Identifies Variants in <i>DSCAM</i> and <i>PDLIM3</i> That Correlate with Efficacy Outcomes in Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib. | Diekstra MHM et al. | β | 2022 | β |
| Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis. | Scholz M et al. | β | 2022 | β |
| GWAS identifies candidate susceptibility loci and microRNA biomarkers for acute encephalopathy with biphasic seizures and late reduced diffusion. | Kasai M et al. | β | 2022 | β |
| HCLC-FC: A novel statistical method for phenome-wide association studies. | Liang X et al. | β | 2022 | β |
| HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution. | Kuo FC et al. | β | 2022 | β |
| Hypothesis-driven genome-wide association studies provide novel insights into genetics of reading disabilities. | Price KM et al. | β | 2022 | β |
| Iam hiQ-a novel pair of accuracy indices for imputed genotypes. | Rosenberger A et al. | β | 2022 | β |
| Identification of genetic effects underlying type 2 diabetes in South Asian and European populations. | Loh M et al. | β | 2022 | β |
| Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study. | Saul N et al. | β | 2022 | β |
| Identification of Shared and Asian-Specific Loci for Systemic Lupus Erythematosus and Evidence for Roles of Type III Interferon Signaling and Lysosomal Function in the Disease: A Multi-Ancestral Genome-Wide Association Study. | Wang YF et al. | β | 2022 | β |
| Identification of shared loci associated with both Crohn's disease and leprosy in East Asians. | Jung S et al. | β | 2022 | β |
| Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with <i>TRAF3</i> mutations. | Rae W et al. | β | 2022 | β |
| Impact of Human Genetic Variation on C-Reactive Protein Concentrations and Acute Appendicitis. | RicaΓ±o-Ponce I et al. | β | 2022 | β |
| Imputation provides an opportunity to study filaggrin ( <i>FLG</i>) null mutations in large population cohorts that lack bespoke genotyping. | Paternoster L et al. | β | 2022 | β |
| Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans. | LemmelΓ€ S et al. | β | 2022 | β |
| Interaction between cigarette smoking and genetic polymorphisms on the associations with age of natural menopause and reproductive lifespan: the Singapore Chinese Health Study. | Huang Z et al. | β | 2022 | β |
| Interactive effects of the low-carbohydrate diet score and genetic risk score on Hypo-HDL-cholesterolemia among Korean adults: A cross-sectional analysis from the Ansan and Ansung Study of the Korean Genome and Epidemiology Study. | Park S et al. | β | 2022 | β |
| <i>BIRC6</i> modifies risk of invasive bacterial infection in Kenyan children. | Gilchrist JJ et al. | β | 2022 | β |
| Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program. | Manichaikul A et al. | β | 2022 | β |
| Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90. | Heath L et al. | β | 2022 | β |
| Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension. | Toshner M et al. | β | 2022 | β |
| Methods for statistical fine-mapping and their applications to auto-immune diseases. | Wang QS et al. | β | 2022 | β |
| Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension. | Harbaum L et al. | β | 2022 | β |
| Multivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants. | Sun J et al. | β | 2022 | β |
| New insights into the genetic etiology of Alzheimer's disease and related dementias. | Bellenguez C et al. | β | 2022 | β |
| On the way to plant data commons - a genotyping use case. | Feser M et al. | β | 2022 | β |
| PHARP: a pig haplotype reference panel for genotype imputation. | Wang Z et al. | β | 2022 | β |
| Phenotype-Genotype analysis of caucasian patients with high risk of osteoarthritis. | Wang Y et al. | β | 2022 | β |
| Prediction of type 2 diabetes using genome-wide polygenic risk score and metabolic profiles: A machine learning analysis of population-based 10-year prospective cohort study. | Hahn SJ et al. | β | 2022 | β |
| Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke. | Chen L et al. | β | 2022 | β |
| The association of genetic susceptibility to smoking with cardiovascular disease mortality and the benefits of adhering to a DASH diet: The Singapore Chinese Health Study. | Geng T et al. | β | 2022 | β |
| The construction of a haplotype reference panel using extremely low coverage whole genome sequences and its application in genome-wide association studies and genomic prediction in Duroc pigs. | Zhang Z et al. | β | 2022 | β |
| The Kinesin Gene <i>KIF26B</i> Modulates the Severity of Post-Traumatic Heterotopic Ossification. | Pickering GAE et al. | β | 2022 | β |
| Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid. | Piekos JA et al. | β | 2022 | β |
| Vascular burden and genetic risk in association with cognitive performance and dementia in a population-based study. | Georgakis MK et al. | β | 2022 | β |
| Verification of immunology-related genetic associations in BPD supports ABCA3 and five other genes. | Blume F et al. | β | 2022 | β |
| A 584Β bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer. | Jermusyk A et al. | β | 2021 | β |
| Accelerated deciphering of the genetic architecture of agricultural economic traits in pigs using a low-coverage whole-genome sequencing strategy. | Yang R et al. | β | 2021 | β |
| Accuracy of genotype imputation based on reference population size and marker density in Hanwoo cattle. | Lee D et al. | β | 2021 | β |
| Accurate imputation of human leukocyte antigens with CookHLA. | Cook S et al. | β | 2021 | β |
| Advances and challenges in quantitative delineation of the genetic architecture of complex traits. | Tang H et al. | β | 2021 | β |
| A genome-wide association study identifies a novel candidate locus at the DLGAP1 gene with susceptibility to resistant hypertension in the Japanese population. | Takahashi Y et al. | β | 2021 | β |
| A genome-wide association study reveals a substantial genetic basis underlying the Ebbinghaus illusion. | Zhu Z et al. | β | 2021 | β |
| A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis. | Bell S et al. | β | 2021 | β |
| A Germline Variant at 8q24 Contributes to the Serum p2PSA Level in a Chinese Prostate Biopsy Cohort. | Lin X et al. | β | 2021 | β |
| A Haptoglobin Exon Copy Number Variant Associates With HIV-Associated Neurocognitive Impairment in European and African-Descent Populations. | Bai H et al. | β | 2021 | β |
| Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders. | Rao X et al. | β | 2021 | β |
| Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans. | Chenoweth MJ et al. | β | 2021 | β |
| An Evaluation of the Diagnostic Accuracy of a Panel of Variants in <i>DPYD</i> and a Single Variant in ENOSF1 for Predicting Common Capecitabine Related Toxicities. | Palles C et al. | β | 2021 | β |
| An evaluation of the predictive performance and mapping power of the BayesR model for genomic prediction. | Mollandin F et al. | β | 2021 | β |
| Association between ABHD1 and DOK6 polymorphisms and susceptibility to Hirschsprung disease in Southern Chinese children. | Lan C et al. | β | 2021 | β |
| Association of <i>HLA-DQA2</i> and <i>HLA-B</i> With Moyamoya Disease in the Chinese Han Population. | Wan J et al. | β | 2021 | β |
| Association of the Polygenic Risk Score With the Probability of Prodromal Parkinson's Disease in Older Adults. | Maraki MI et al. | β | 2021 | β |
| Associations between common genetic variants in microRNAs and Hirschsprung disease susceptibility in Southern Chinese children. | Wu Q et al. | β | 2021 | β |
| Associations of biogeographic ancestry with hypertension traits. | Keaton JM et al. | β | 2021 | β |
| Bivariate genome-wide association study (GWAS) of body mass index and blood pressure phenotypes in northern Chinese twins. | Li Z et al. | β | 2021 | β |
| Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress. | Martins J et al. | β | 2021 | β |
| Combination of Genome-Wide Polymorphisms and Copy Number Variations of Pharmacogenes in Koreans. | Han N et al. | β | 2021 | β |
| Common Susceptibility Loci for Male Breast Cancer. | Maguire S et al. | β | 2021 | β |
| Common Variants Associated With <i>OSMR</i> Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans. | van Keulen D et al. | β | 2021 | β |
| CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. | Johnson N et al. | β | 2021 | β |
| Demystifying emerging bulk RNA-Seq applications: the application and utility of bioinformatic methodology. | Thind AS et al. | β | 2021 | β |
| Detecting selected haplotype blocks in evolve and resequence experiments. | Otte KA et al. | β | 2021 | β |
| Differential genetic influences over colorectal cancer risk and gene expression in large bowel mucosa. | Vaughan-Shaw PG et al. | β | 2021 | β |
| Dissecting the contribution of single nucleotide polymorphisms in <i>CCR9</i> and <i>CCL25</i> genomic regions to the celiac disease phenotype. | Airaksinen L et al. | β | 2021 | β |
| Efficient phasing and imputation of low-coverage sequencing data using large reference panels. | Rubinacci S et al. | β | 2021 | β |
| Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor. | Dowsett J et al. | β | 2021 | β |
| Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals. | Hivert V et al. | β | 2021 | β |
| Evidence for specificity of polygenic contributions to attainment in English, maths and science during adolescence. | Donati G et al. | β | 2021 | β |
| False positive findings during genome-wide association studies with imputation: influence of allele frequency and imputation accuracy. | Zhang Z et al. | β | 2021 | β |
| Fast two-stage phasing of large-scale sequence data. | Browning BL et al. | β | 2021 | β |
| Fine scale human genetic structure in three regions of Cameroon reveals episodic diversifying selection. | Esoh KK et al. | β | 2021 | β |
| Genetic Architecture of Depression: Where Do We Stand Now? | Unal-Aydin P et al. | β | 2021 | β |
| Genetic polymorphisms at 19q13.33 are associated with [-2]proPSA (p2PSA) levels and provide additional predictive value to prostate health index for prostate cancer. | Huang D et al. | β | 2021 | β |
| Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism. | Li-Gao R et al. | β | 2021 | β |
| Genetic variant in <i>microRNA-146a</i> gene is associated with risk of rheumatoid arthritis. | Zhang LL et al. | β | 2021 | β |
| Genetic Variations in Thiamin Transferase <i>SLC35F3</i> and the Risk of Hypertension in Koreans. | Seo JY et al. | β | 2021 | β |
| Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes. | Mansour Aly D et al. | β | 2021 | β |
| Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration. | Bourgeois S et al. | β | 2021 | β |
| Genome-Wide Association Meta-Analysis Supports Genes Involved in Valve and Cardiac Development to Associate With Mitral Valve Prolapse. | Yu M et al. | β | 2021 | β |
| Genome-Wide Association Study for Body Length, Body Height, and Total Teat Number in Large White Pigs. | Hong Y et al. | β | 2021 | β |
| Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in known glycemic loci in Chilean adolescents: The Santiago Longitudinal Study. | Buchanan VL et al. | β | 2021 | β |
| Genome-wide association study of circulating interleukin 6 levels identifies novel loci. | Ahluwalia TS et al. | β | 2021 | β |
| Genome-wide association study of COVID-19 severity among the Chinese population. | Li Y et al. | β | 2021 | β |
| Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. | Palmer ND et al. | β | 2021 | β |
| Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population. | Hebbar P et al. | β | 2021 | β |
| Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. | Dawed AY et al. | β | 2021 | β |
| Genome-wide search for genes affecting the age at diagnosis of type 1 diabetes. | Syreeni A et al. | β | 2021 | β |
| Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. | Liu G et al. | β | 2021 | β |
| Genomic Prediction Using LD-Based Haplotypes Inferred From High-Density Chip and Imputed Sequence Variants in Chinese Simmental Beef Cattle. | Li H et al. | β | 2021 | β |
| Germline Variation and Somatic Alterations in Ewing Sarcoma. | Machiela MJ et al. | β | 2021 | β |
| GW-SEM 2.0: Efficient, Flexible, and Accessible Multivariate GWAS. | Pritikin JN et al. | β | 2021 | β |
| Heritability and genome-wide association study of blood pressure in Chinese adult twins. | Chen J et al. | β | 2021 | β |
| Highly accurate whole-genome imputation of SARS-CoV-2 from partial or low-quality sequences. | OrtuΓ±o FM et al. | β | 2021 | β |
| Host Genome-Wide Association Study of Infant Susceptibility to <i>Shigella</i>-Associated Diarrhea. | Duchen D et al. | β | 2021 | β |
| How imputation can mitigate SNP ascertainment Bias. | Geibel J et al. | β | 2021 | β |
| Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups. | Wang YF et al. | β | 2021 | β |
| Identification of Three Novel Susceptibility Loci for Inflammatory Bowel Disease in Koreans in an Extended Genome-Wide Association Study. | Jung S et al. | β | 2021 | β |
| Identifying tumorigenic non-coding mutations through altered <i>cis</i>-regulation. | Cheng Z et al. | β | 2021 | β |
| Improving the resolution of canine genome-wide association studies using genotype imputation: A study of two breeds. | Jenkins CA et al. | β | 2021 | β |
| Imputation Performance in Latin American Populations: Improving Rare Variants Representation With the Inclusion of Native American Genomes. | JimΓ©nez-Kaufmann A et al. | β | 2021 | β |
| Increasing calling accuracy, coverage, and read-depth in sequence data by the use of haplotype blocks. | Pook T et al. | β | 2021 | β |
| Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes. | Cerqueira JXM et al. | β | 2021 | β |
| Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. | Matzaraki V et al. | β | 2021 | β |
| Integration of genome-wide association study and expression quantitative trait locus mapping for identification of endometriosis-associated genes. | Chou YC et al. | β | 2021 | β |
| Integrative approaches generate insights into the architecture of non-syndromic cleft lip with or without cleft palate. | Welzenbach J et al. | β | 2021 | β |
| Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs. | Sakurai-Yageta M et al. | β | 2021 | β |
| Kleine-Levin syndrome is associated with birth difficulties and genetic variants in the <i>TRANK1</i> gene loci. | Ambati A et al. | β | 2021 | β |
| Large-Scale Screening for Monogenic and Clinically Defined Familial Hypercholesterolemia in Iceland. | BjΓΆrnsson E et al. | β | 2021 | β |
| Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population. | Chang X et al. | β | 2021 | β |
| Mapping gene and gene pathways associated with coronary artery disease: a CARDIoGRAM exome and multi-ancestry UK biobank analysis. | Hariharan P et al. | β | 2021 | β |
| Metabolic profiling of maternal serum of women at high-risk of spontaneous preterm birth using NMR and MGWAS approach. | Gupta JK et al. | β | 2021 | β |
| Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis. | Blaser MC et al. | β | 2021 | β |
| Multiple haplotype reconstruction from allele frequency data. | Pelizzola M et al. | β | 2021 | β |
| Multivariate Analysis and Modelling of multiple Brain endOphenotypes: Let's MAMBO! | Vilor-Tejedor N et al. | β | 2021 | β |
| Polygenic basis and biomedical consequences of telomere length variation. | Codd V et al. | β | 2021 | β |
| Polymorphism in the MAGI2 Gene Modifies the Effect of Amyloid Ξ² on Neurodegeneration. | Kim HR et al. | β | 2021 | β |
| Privacy-preserving genotype imputation in a trusted execution environment. | Dokmai N et al. | β | 2021 | β |
| Protein-coding repeat polymorphisms strongly shape diverse human phenotypes. | Mukamel RE et al. | β | 2021 | β |
| Quantitative MRI phenotypes capture biological heterogeneity in multiple sclerosis patients. | Smets I et al. | β | 2021 | β |
| Recommendations for Statistical Reporting in Cardiovascular Medicine: A Special Report From the American Heart Association. | Althouse AD et al. | β | 2021 | β |
| Sepsis: deriving biological meaning and clinical applications from high-dimensional data. | Schuurman AR et al. | β | 2021 | β |
| Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. | Lagou V et al. | β | 2021 | β |
| Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma. | Carrera C et al. | β | 2021 | β |
| Sleep Polygenic Risk Score Is Associated with Cognitive Changes over Time. | Tsapanou A et al. | β | 2021 | β |
| SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression. | Hou G et al. | β | 2021 | β |
| TIGER: The gene expression regulatory variation landscape of human pancreatic islets. | Alonso L et al. | β | 2021 | β |
| Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. | Conti DV et al. | β | 2021 | β |
| Transferability of Ancestry-Specific and Cross-Ancestry CYP2A6 Activity Genetic Risk Scores in African and European Populations. | El-Boraie A et al. | β | 2021 | β |
| Two-Sample Mendelian Randomization Analysis of Associations Between Periodontal Disease and Risk of Cancer. | Corlin L et al. | β | 2021 | β |
| Whole-exome sequencing reveals common and rare variants in immunologic and neurological genes implicated in achalasia. | Li Q et al. | β | 2021 | β |
| Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. | Somineni HK et al. | β | 2021 | β |
| Adiponectin and leptin in the diagnosis and therapy of NAFLD. | Boutari C et al. | β | 2020 | β |
| A general framework for integrative analysis of incomplete multiomics data. | Lin DY et al. | β | 2020 | β |
| A genome-wide association study on medulloblastoma. | Dahlin AM et al. | β | 2020 | β |
| A Genome-Wide Pharmacogenetic Study of Growth Hormone Responsiveness. | Dauber A et al. | β | 2020 | β |
| Animal-ImputeDB: a comprehensive database with multiple animal reference panels for genotype imputation. | Yang W et al. | β | 2020 | β |
| A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants. | Kanders SH et al. | β | 2020 | β |
| A Unifying Framework for Imputing Summary Statistics in Genome-Wide Association Studies. | Wu Y et al. | β | 2020 | β |
| Broad- and narrow-sense validity performance of three polygenic risk score methods for prostate cancer risk assessment. | Yu H et al. | β | 2020 | β |
| Desaturase Activity and the Risk of Type 2 Diabetes and Coronary Artery Disease: A Mendelian Randomization Study. | JΓ€ger S et al. | β | 2020 | β |
| Detecting Shared Genetic Architecture Among Multiple Phenotypes by Hierarchical Clustering of Gene-Level Association Statistics. | McGuirl MR et al. | β | 2020 | β |
| Discovery of novel hepatocyte eQTLs in African Americans. | Zhong Y et al. | β | 2020 | β |
| Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis. | Dapas M et al. | β | 2020 | β |
| Education leads to a more physically active lifestyle: Evidence based on Mendelian randomization. | Kari JT et al. | β | 2020 | β |
| Effect of plasma polyunsaturated fatty acid levels on leukocyte telomere lengths in the Singaporean Chinese population. | Chang X et al. | β | 2020 | β |
| Eicosanoid Inflammatory Mediators Are Robustly Associated With Blood Pressure in the General Population. | Palmu J et al. | β | 2020 | β |
| European genetic ancestry associated with risk of childhood ependymoma. | Zhang C et al. | β | 2020 | β |
| Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity. | El-Boraie A et al. | β | 2020 | β |
| Exome sequencing and characterization of 49,960 individuals in the UK Biobank. | Van Hout CV et al. | β | 2020 | β |
| Expression Quantitative Trait Loci (eQTL) Mapping in Korean Patients With Crohn's Disease and Identification of Potential Causal Genes Through Integration With Disease Associations. | Jung S et al. | β | 2020 | β |
| FADS3 is a Ξ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome. | Karsai G et al. | β | 2020 | β |
| Family-based genome-wide association study of leprosy in Vietnam. | Gzara C et al. | β | 2020 | β |
| Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. | Fachal L et al. | β | 2020 | β |
| Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC. | Mishra R et al. | β | 2020 | β |
| Genetic predictors of hippocampal subfield volume in PTSD cases and trauma-exposed controls. | Morey RA et al. | β | 2020 | β |
| Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. | Steinthorsdottir V et al. | β | 2020 | β |
| Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma. | Zhang C et al. | β | 2020 | β |
| Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study. | Jin G et al. | β | 2020 | β |
| Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies. | Matana A et al. | β | 2020 | β |
| Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity. | Chen L et al. | β | 2020 | β |
| Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. | Li C et al. | β | 2020 | β |
| Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. | Shah S et al. | β | 2020 | β |
| Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. | Fan Q et al. | β | 2020 | β |
| Genome-wide associations of human gut microbiome variation and implications for causal inference analyses. | Hughes DA et al. | β | 2020 | β |
| Genome-wide association studies of the self-rating of effects of ethanol (SRE). | Lai D et al. | β | 2020 | β |
| Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk. | Yuan F et al. | β | 2020 | β |
| Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway. | Manry J et al. | β | 2020 | β |
| Genome-Wide Association Study of Cryptosporidiosis in Infants Implicates <i>PRKCA</i>. | Wojcik GL et al. | β | 2020 | β |
| Genome-wide association study of emotional empathy in children. | Woodbury-Smith MR et al. | β | 2020 | β |
| Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis. | Allen RJ et al. | β | 2020 | β |
| Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain. | Cullell N et al. | β | 2020 | β |
| Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes. | Chen J et al. | β | 2020 | β |
| Genomics to accelerate genetic improvement in tilapia. | YÑñez JM et al. | β | 2020 | β |
| Glioma risk associated with extent of estimated European genetic ancestry in African Americans and Hispanics. | Ostrom QT et al. | β | 2020 | β |
| Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases. | KlariΔ L et al. | β | 2020 | β |
| Heritability and genome-wide association analyses of fasting plasma glucose in Chinese adult twins. | Wang W et al. | β | 2020 | β |
| High-activity Classical and Alternative Complement Pathway Genotypes-Association With Donor-specific Antibody-triggered Injury and Renal Allograft Survival. | MezΕ B et al. | β | 2020 | β |
| How Well Can Multivariate and Univariate GWAS Distinguish Between True and Spurious Pleiotropy? | Fernandes SB et al. | β | 2020 | β |
| Identification of ALK in Thinness. | Orthofer M et al. | β | 2020 | β |
| Identification of Genetic Variants for Female Obesity and Evaluation of the Causal Role of Genetically Defined Obesity in Polycystic Ovarian Syndrome. | Ahn Y et al. | β | 2020 | β |
| Identification of new susceptibility loci associated with rheumatoid arthritis. | Leng RX et al. | β | 2020 | β |
| Identification of novel epithelial ovarian cancer loci in women of African ancestry. | Manichaikul A et al. | β | 2020 | β |
| Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype. | Kim BH et al. | β | 2020 | β |
| Identification of Novel Genetic Variants Related to Trabecular Bone Score in Community-Dwelling Older Adults. | Kong SH et al. | β | 2020 | β |
| Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study. | Magnus MC et al. | β | 2020 | β |
| Improving Imputation Quality in BEAGLE for Crop and Livestock Data. | Pook T et al. | β | 2020 | β |
| Integration of transcriptome-wide association study and messenger RNA expression profile to identify genes associated with osteoarthritis. | Qi X et al. | β | 2020 | β |
| Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies. | Ainsworth HC et al. | β | 2020 | β |
| Maternal vitamin D status during pregnancy and offspring risk of childhood/adolescent depression: Results from the Avon Longitudinal Study of Parents and Children (ALSPAC). | Wang MJ et al. | β | 2020 | β |
| Mendelian Randomization Study on Amino Acid Metabolism Suggests Tyrosine as Causal Trait for Type 2 Diabetes. | JΓ€ger S et al. | β | 2020 | β |
| Meta-analysis of genome-wide association studies and functional assays decipher susceptibility genes for gastric cancer in Chinese populations. | Yan C et al. | β | 2020 | β |
| Methodological challenges in constructing DNA methylation risk scores. | HΓΌls A et al. | β | 2020 | β |
| OPENMENDEL: a cooperative programming project for statistical genetics. | Zhou H et al. | β | 2020 | β |
| Pharmacogenetic and safety analysis of cinacalcet hydrochloride in healthy Chinese subjects. | Liu YJ et al. | β | 2020 | β |
| Phenome-wide analyses establish a specific association between aortic valve PALMD expression and calcific aortic valve stenosis. | Li Z et al. | β | 2020 | β |
| Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases. | Howe LJ et al. | β | 2020 | β |
| Polygenic risk scores indicates genetic overlap between peripheral pain syndromes and chronic postsurgical pain. | van Reij RRI et al. | β | 2020 | β |
| Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy. | Kerns SL et al. | β | 2020 | β |
| Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes. | Forgetta V et al. | β | 2020 | β |
| Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies. | Ran S et al. | β | 2020 | β |
| Sex-Specific Genetic Associations for Barrett's Esophagus and Esophageal Adenocarcinoma. | Dong J et al. | β | 2020 | β |
| The association between genome-wide polymorphisms and chronic postoperative pain: a prospective observational study. | van Reij RRI et al. | β | 2020 | β |
| The biological classification of mental disorders (BeCOME) study: a protocol for an observational deep-phenotyping study for the identification of biological subtypes. | BrΓΌckl TM et al. | β | 2020 | β |
| The influence of common polygenic risk and gene sets on social skills group training response in autism spectrum disorder. | Li D et al. | β | 2020 | β |
| Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease. | Sekula P et al. | β | 2020 | β |
| Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study. | Gudmundsdottir V et al. | β | 2020 | β |
| A catalog of genetic loci associated with kidney function from analyses of a million individuals. | Wuttke M et al. | β | 2019 | β |
| A comprehensive survey of models for dissecting local ancestry deconvolution in human genome. | Geza E et al. | β | 2019 | β |
| A Fast and Flexible Framework for Network-Assisted Genomic Association. | Carlin DE et al. | β | 2019 | β |
| Age at menarche and epithelial ovarian cancer risk: A meta-analysisΒ and Mendelian randomization study. | Yang H et al. | β | 2019 | β |
| A genome-wide association and replication study of blood pressure in Ugandan early adolescents. | Lule SA et al. | β | 2019 | β |
| A genome wide association study identifies new genes potentially associated with eyelid sagging. | Laville V et al. | β | 2019 | β |
| A genome-wide association study identifies susceptibility loci for primary central nervous system lymphoma at 6p25.3 and 3p22.1: a LOC Network study. | Labreche K et al. | β | 2019 | β |
| A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. | Guyatt AL et al. | β | 2019 | β |
| A <i>Trans</i>-Ethnic Genome-Wide Association Study of Uterine Fibroids. | Edwards TL et al. | β | 2019 | β |
| A Mendelian randomization study of IL6 signaling in cardiovascular diseases, immune-related disorders and longevity. | Rosa M et al. | β | 2019 | β |
| A meta-analysis of Italian and Estonian individuals shows an effect of common variants in <i>HMGCR</i> on blood apoB levels. | Rosticci M et al. | β | 2019 | β |
| An optimal kernel-based U-statistic method for quantitative gene-set association analysis. | He T et al. | β | 2019 | β |
| A phenomics-based approach for the detection and interpretation of shared genetic influences on 29 biochemical indices in southern Chinese men. | Hu Y et al. | β | 2019 | β |
| A Random Forests Framework for Modeling Haplotypes as Mosaics of Reference Haplotypes. | Faux P et al. | β | 2019 | β |
| A resource-efficient tool for mixed model association analysis of large-scale data. | Jiang L et al. | β | 2019 | β |
| A Single Nucleotide C3 Polymorphism Associates With Clinical Outcome After Lung Transplantation. | Kardol-Hoefnagel T et al. | β | 2019 | β |
| Assessment of Molecular Subtypes in Thyrotoxic Periodic Paralysis and Graves Disease Among Chinese Han Adults: A Population-Based Genome-Wide Association Study. | Zhao SX et al. | β | 2019 | β |
| Association analyses identify 31 new risk loci for colorectal cancer susceptibility. | Law PJ et al. | β | 2019 | β |
| Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits. | Legge SE et al. | β | 2019 | β |
| A statistical framework for cross-tissue transcriptome-wide association analysis. | Hu Y et al. | β | 2019 | β |
| Challenges in funding and developing genomic software: roots and remedies. | Siepel A | β | 2019 | β |
| Chromatin three-dimensional interactions mediate genetic effects on gene expression. | Delaneau O et al. | β | 2019 | β |
| Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE Ξ΅4 Non-Carriers. | Huentelman M et al. | β | 2019 | β |
| Concept and benchmarks for assessing narrow-sense validity of genetic risk score values. | Yu H et al. | β | 2019 | β |
| Contribution of non-HLA incompatibility between donor and recipient to kidney allograft survival: genome-wide analysis in a prospective cohort. | Reindl-Schwaighofer R et al. | β | 2019 | β |
| Cross-Cancer Pleiotropic Associations with Lung Cancer Risk in African Americans. | Jones CC et al. | β | 2019 | β |
| Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes. | Chung W et al. | β | 2019 | β |
| Efficient estimation of grouped survival models. | Li Z et al. | β | 2019 | β |
| Evaluating the quality of the 1000 genomes project data. | Belsare S et al. | β | 2019 | β |
| Evidence of a Causal Association Between Cancer and Alzheimer's Disease: a Mendelian Randomization Analysis. | Seddighi S et al. | β | 2019 | β |
| Exploring Shared Susceptibility between Two Neural Crest Cells Originating Conditions: Neuroblastoma and Congenital Heart Disease. | Testori A et al. | β | 2019 | β |
| First genotype-phenotype study reveals HLA-DQΞ²1 insertion heterogeneity in high-resolution manometry achalasia subtypes. | Vackova Z et al. | β | 2019 | β |
| Gene hunting with hidden Markov model knockoffs. | Sesia M et al. | β | 2019 | β |
| Genetic architecture of human thinness compared to severe obesity. | Riveros-McKay F et al. | β | 2019 | β |
| Genetic influences on susceptibility to rheumatoid arthritis in African-Americans. | Laufer VA et al. | β | 2019 | β |
| Genetic predisposition to B-cell acute lymphoblastic leukemia at 14q11.2 is mediated by a CEBPE promoter polymorphism. | Studd JB et al. | β | 2019 | β |
| Genetic risk factors for the development of pulmonary disease identified by genome-wide association. | Hall R et al. | β | 2019 | β |
| Genetic risk factors identified in populations of European descent do not improve the prediction of osteoporotic fracture and bone mineral density in Chinese populations. | Li YM et al. | β | 2019 | β |
| Genetic risk score modifies the effect of APOE on risk and age onset of Alzheimer's disease. | Shi Z et al. | β | 2019 | β |
| Genetic Susceptibility to Chronic Kidney Disease - Some More Pieces for the Heritability Puzzle. | CaΓ±adas-Garre M et al. | β | 2019 | β |
| Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. | Kottyan LC et al. | β | 2019 | β |
| Genetic Variants in the 9p21.3 Locus Associated with Glioma Risk in Children, Adolescents, and Young Adults: A Case-Control Study. | Dahlin AM et al. | β | 2019 | β |
| Genetic Variants in the <i>ST6GAL1</i> Gene Are Associated with Thyroglobulin Plasma Level in Healthy Individuals. | Matana A et al. | β | 2019 | β |
| Genetic Variants of <i>VEGFA</i> and <i>FLT4</i> Are Determinants of Survival in Renal Cell Carcinoma Patients Treated with Sorafenib. | Crona DJ et al. | β | 2019 | β |
| Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis. | Aterido A et al. | β | 2019 | β |
| Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics. | Yazdani A et al. | β | 2019 | β |
| Genome-wide association analysis of 95β549 individuals identifies novel loci and genes influencing optic disc morphology. | Han X et al. | β | 2019 | β |
| Genome-wide association and gene-environment interaction study identifies variants in ALDH2 associated with serum ferritin in a Chinese population. | Tao Y et al. | β | 2019 | β |
| Genome-wide association and genotype by environment interactions for growth traits in U.S. Gelbvieh cattle. | Smith JL et al. | β | 2019 | β |
| Genome-wide association meta-analysis and Mendelian randomization analysis confirm the influence of ALDH2 on sleep durationin the Japanese population. | Nishiyama T et al. | β | 2019 | β |
| Genome-wide association meta-analysis for total thyroid hormone levels in Croatian population. | GunjaΔa I et al. | β | 2019 | β |
| Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. | Guan M et al. | β | 2019 | β |
| Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns. | Sliz E et al. | β | 2019 | β |
| Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison. | Sun Y et al. | β | 2019 | β |
| Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals. | Liu CT et al. | β | 2019 | β |
| Genome-Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education. | Donati G et al. | β | 2019 | β |
| Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study. | Westphal S et al. | β | 2019 | β |
| Genomewide Association Study of Statin-Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink. | Carr DF et al. | β | 2019 | β |
| Genome-wide association study of type 2 diabetes in Africa. | Chen J et al. | β | 2019 | β |
| Genome-Wide Association Study on the Early-Phase Insulin Response to a Liquid Mixed Meal: Results From the NEO Study. | Li-Gao R et al. | β | 2019 | β |
| Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians. | Matana A et al. | β | 2019 | β |
| Genome-wide meta-analysis identifies novel loci associated with free triiodothyronine and thyroid-stimulating hormone. | PopoviΔ M et al. | β | 2019 | β |
| Gimpute: an efficient genetic data imputation pipeline. | Chen J et al. | β | 2019 | β |
| GWAS of Behavioral Traits. | Mehta D et al. | β | 2019 | β |
| GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures. | Styrkarsdottir U et al. | β | 2019 | β |
| gwasurvivr: an R package for genome-wide survival analysis. | Rizvi AA et al. | β | 2019 | β |
| Heritability of human visual contour integration-an integrated genomic study. | Zhu Z et al. | β | 2019 | β |
| Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk. | Vijayakrishnan J et al. | β | 2019 | β |
| Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. | Dai J et al. | β | 2019 | β |
| iFunMed: Integrative functional mediation analysis of GWAS and eQTL studies. | Rojo C et al. | β | 2019 | β |
| Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies. | Wu Y et al. | β | 2019 | β |
| Imputation accuracy of wheat genotyping-by-sequencing (GBS) data using barley and wheat genome references. | Alipour H et al. | β | 2019 | β |
| Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics. | Speedy HE et al. | β | 2019 | β |
| Integrated Analysis of Human Milk Microbiota With Oligosaccharides and Fatty Acids in the CHILD Cohort. | Moossavi S et al. | β | 2019 | β |
| Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus. | Odhams CA et al. | β | 2019 | β |
| Investigation of the predisposing factor of pemphigus and its clinical subtype through a genome-wide association and next generation sequence analysis. | Sun Y et al. | β | 2019 | β |
| Low Birth Weight and Kidney Function in Middle-Aged Men and Women: The Netherlands Epidemiology of Obesity Study. | Esmeijer K et al. | β | 2019 | β |
| Low-frequency variation in TP53 has large effects on head circumference and intracranial volume. | Haworth S et al. | β | 2019 | β |
| Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. | Hellwege JN et al. | β | 2019 | β |
| Mendelian randomization reveals unexpected effects of CETP on the lipoprotein profile. | Blauw LL et al. | β | 2019 | β |
| Meta-Analysis of Genome-Wide Association Studies Identifies Three Loci Associated With Stiffness Index of the Calcaneus. | Lu HF et al. | β | 2019 | β |
| Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry. | Hsu YH et al. | β | 2019 | β |
| Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. | Shrine N et al. | β | 2019 | β |
| Multi-marker analysis of genomic annotation on gastric cancer GWAS data from Chinese populations. | Yu F et al. | β | 2019 | β |
| Multivariate generalized linear model for genetic pleiotropy. | Schaid DJ et al. | β | 2019 | β |
| NBN Gene Analysis and it's Impact on Breast Cancer. | Nithya P et al. | β | 2019 | β |
| Neuroblastoma in relation to joint effects of vitamin A and maternal and offspring variants in vitamin A-related genes: A report of the Children's Oncology Group. | Mazul AL et al. | β | 2019 | β |
| Odyssey: a semi-automated pipeline for phasing, imputation, and analysis of genome-wide genetic data. | Eller RJ et al. | β | 2019 | β |
| Optimizing the Power to Identify the Genetic Basis of Complex Traits with Evolve and Resequence Studies. | Vlachos C et al. | β | 2019 | β |
| Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer. | Gray V et al. | β | 2019 | β |
| Phasing quality assessment in a brown layer population through family- and population-based software. | Frioni N et al. | β | 2019 | β |
| Polygenic Risk Score Analysis of Alzheimer's Disease in Cases without APOE4 or APOE2 Alleles. | Escott-Price V et al. | β | 2019 | β |
| Polygenic Susceptibility of Aortic Aneurysms Associates to the Diameter of the Aneurysm Sac: the Aneurysm-Express Biobank Cohort. | van Laarhoven CJHCM et al. | β | 2019 | β |
| Primary closed angle glaucoma in the Basset Hound: Genetic investigations using genome-wide association and RNA sequencing strategies. | Oliver JAC et al. | β | 2019 | β |
| Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics. | Tynkkynen T et al. | β | 2019 | β |
| Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. | Justice AE et al. | β | 2019 | β |
| Rare and common variant discovery in complex disease: the IBD case study. | Venkataraman GR et al. | β | 2019 | β |
| Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry. | Yang Y et al. | β | 2019 | β |
| Risk of spontaneous preterm birth and fetal growth associates with fetal SLIT2. | Tiensuu H et al. | β | 2019 | β |
| Salt stress under the scalpel - dissecting the genetics of salt tolerance. | Morton MJL et al. | β | 2019 | β |
| Sequence imputation from low density single nucleotide polymorphism panel in a black poplar breeding population. | PΓ©gard M et al. | β | 2019 | β |
| Sex-specific gene and pathway modeling of inherited glioma risk. | Ostrom QT et al. | β | 2019 | β |
| simGWAS: a fast method for simulation of large scale case-control GWAS summary statistics. | Fortune MD et al. | β | 2019 | β |
| Sparse Convolutional Denoising Autoencoders for Genotype Imputation. | Chen J et al. | β | 2019 | β |
| Statistical methods for genome-wide association studies. | Wang MH et al. | β | 2019 | β |
| Systematic evaluation of cancer-specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts. | Shi Z et al. | β | 2019 | β |
| The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA? | MacInnes SJ et al. | β | 2019 | β |
| The Challenges of Chromosome Y Analysis and the Implications for Chronic Kidney Disease. | Anderson K et al. | β | 2019 | β |
| The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits. | Moon S et al. | β | 2019 | β |
| The myopia susceptibility locus vasoactive intestinal peptide receptor 2 (VIPR2) contains variants with opposite effects. | Leung KH et al. | β | 2019 | β |
| Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. | Giri A et al. | β | 2019 | β |
| Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry. | Bustos BI et al. | β | 2019 | β |
| Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by <i>SLC29A4</i>) and Organic Cation Transporter 1 (OCT1) (Encoded by <i>SLC22A1</i>) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study. | Dawed AY et al. | β | 2019 | β |
| A dense mapping study of six European AITD susceptibility regions in a large Chinese Han Cohort of Graves' disease. | Liu W et al. | β | 2018 | β |
| Adjusted likelihood-ratio test for variants with unknown genotypes. | Nowling RJ et al. | β | 2018 | β |
| Admixture mapping and fine-mapping of birth weight loci in the Black Women's Health Study. | Ochs-Balcom HM et al. | β | 2018 | β |
| Advances in understanding the genetic basis of diabetic kidney disease. | Li M et al. | β | 2018 | β |
| A fine-mapping study of central obesity loci incorporating functional annotation and imputation. | Zhang X et al. | β | 2018 | β |
| A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1. | Chen Y et al. | β | 2018 | β |
| A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. | van Zuydam NR et al. | β | 2018 | β |
| A Genome-wide Expression Association Analysis Identifies Genes and Pathways Associated with Amyotrophic Lateral Sclerosis. | Du Y et al. | β | 2018 | β |
| A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome. | Bonfiglio F et al. | β | 2018 | β |
| A hierarchical clustering method for dimension reduction in joint analysis of multiple phenotypes. | Liang X et al. | β | 2018 | β |
| A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood. | Jiang J et al. | β | 2018 | β |
| An Exome-wide Association Study for Type 2 Diabetes-Attributed End-Stage Kidney Disease in African Americans. | Guan M et al. | β | 2018 | β |
| A One-Penny Imputed Genome from Next-Generation Reference Panels. | Browning BL et al. | β | 2018 | β |
| A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. | Patel ZH et al. | β | 2018 | β |
| A rare missense mutation in MYH6 associates with non-syndromic coarctation of the aorta. | Bjornsson T et al. | β | 2018 | β |
| ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties. | St Pourcain B et al. | β | 2018 | β |
| Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study. | Ong JS et al. | β | 2018 | β |
| Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin. | Rafnar T et al. | β | 2018 | β |
| Association of Genetic Variation at <i>AQP4</i> Locus with Vascular Depression. | Westermair AL et al. | β | 2018 | β |
| Association of Genetic Variation in the Epithelial Sodium Channel Gene with Urinary Sodium Excretion and Blood Pressure. | Yang YJ et al. | β | 2018 | β |
| Association of modifiers and other genetic factors explain Marfan syndrome clinical variability. | Aubart M et al. | β | 2018 | β |
| Association of NRG1 and AUTS2 genetic polymorphisms with Hirschsprung disease in a South Chinese population. | Zhang Y et al. | β | 2018 | β |
| Association of VAMP5 and MCC genetic polymorphisms with increased risk of Hirschsprung disease susceptibility in Southern Chinese children. | Zhao J et al. | β | 2018 | β |
| A system-based analysis of the genetic determinism of udder conformation and health phenotypes across three French dairy cattle breeds. | Marete A et al. | β | 2018 | β |
| A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis. | ThΓ©riault S et al. | β | 2018 | β |
| A tutorial on conducting genome-wide association studies: Quality control and statistical analysis. | Marees AT et al. | β | 2018 | β |
| Bayesian multiple logistic regression for case-control GWAS. | Banerjee S et al. | β | 2018 | β |
| Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients. | Campo C et al. | β | 2018 | β |
| Colon-specific eQTL analysis to inform on functional SNPs. | Moreno V et al. | β | 2018 | β |
| Combined linkage and association analysis of classical Hodgkin lymphoma. | Lawrie A et al. | β | 2018 | β |
| Common genetic variation and novel loci associated with volumetric mammographic density. | Brand JS et al. | β | 2018 | β |
| Common variants at 5q33.1 predispose to migraine in African-American children. | Chang X et al. | β | 2018 | β |
| Comparison of methods for transcriptome imputation through application to two common complex diseases. | Fryett JJ et al. | β | 2018 | β |
| Cross-species molecular dissection across alcohol behavioral domains. | Farris SP et al. | β | 2018 | β |
| Design of low density SNP chips for genotype imputation in layer chicken. | Herry F et al. | β | 2018 | β |
| Detection of Significant Association Between Variants in Cannabinoid Receptor 1 Gene (<i>CNR1</i>) and Personality in African-American Population. | Yao Y et al. | β | 2018 | β |
| Diffuse gliomas classified by 1p/19q co-deletion, TERT promoter and IDH mutation status are associated with specific genetic risk loci. | Labreche K et al. | β | 2018 | β |
| Does education protect against depression? Evidence from the Young Finns Study using Mendelian randomization. | Viinikainen J et al. | β | 2018 | β |
| Efficient algorithms for polyploid haplotype phasing. | He D et al. | β | 2018 | β |
| Evaluation and application of summary statistic imputation to discover new height-associated loci. | RΓΌeger S et al. | β | 2018 | β |
| Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia. | Hackinger S et al. | β | 2018 | β |
| Evidence for PTGER4, PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level. | Heinrichs SKM et al. | β | 2018 | β |
| Exploring the association of genetic factors with participation in the Avon Longitudinal Study of Parents and Children. | Taylor AE et al. | β | 2018 | β |
| Fast score test with global null estimation regardless of missing genotypes. | Sato S et al. | β | 2018 | β |
| First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. | Cousminer DL et al. | β | 2018 | β |
| From genome-wide associations to candidate causal variants by statistical fine-mapping. | Schaid DJ et al. | β | 2018 | β |
| Gene-diet interaction effects on BMI levels in the Singapore Chinese population. | Chang X et al. | β | 2018 | β |
| Genetic analysis of deep phenotyping projects in common disorders. | Gershon ES et al. | β | 2018 | β |
| Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators. | Lagou V et al. | β | 2018 | β |
| Genetic contributions to self-reported tiredness. | Deary V et al. | β | 2018 | β |
| Genetic contributions to Trail Making Test performance in UK Biobank. | Hagenaars SP et al. | β | 2018 | β |
| Genetic Control of Left Atrial Gene Expression Yields Insights into the Genetic Susceptibility for Atrial Fibrillation. | Hsu J et al. | β | 2018 | β |
| Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology. | Went M et al. | β | 2018 | β |
| Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses. | Painter JN et al. | β | 2018 | β |
| Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes. | Pott J et al. | β | 2018 | β |
| Genetic studies of human neuropathic pain conditions: a review. | Zorina-Lichtenwalter K et al. | β | 2018 | β |
| Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci. | Scelsi MA et al. | β | 2018 | β |
| Genetic variation in <i>CFH</i> predicts phenytoin-induced maculopapular exanthema in European-descent patients. | McCormack M et al. | β | 2018 | β |
| Genetic variations in TAS2R3 and TAS2R4 bitterness receptors modify papillary carcinoma risk and thyroid function in Korean females. | Choi JH et al. | β | 2018 | β |
| Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences. | Manzoni C et al. | β | 2018 | β |
| Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. | Zengini E et al. | β | 2018 | β |
| Genome-wide analysis yields new loci associating with aortic valve stenosis. | Helgadottir A et al. | β | 2018 | β |
| Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. | Claus EB et al. | β | 2018 | β |
| Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population. | Zhou S et al. | β | 2018 | β |
| Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. | Tedja MS et al. | β | 2018 | β |
| Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium. | de Oliveira Otto MC et al. | β | 2018 | β |
| Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. | Vijayakrishnan J et al. | β | 2018 | β |
| Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma. | Sud A et al. | β | 2018 | β |
| Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery. | Karhausen JA et al. | β | 2018 | β |
| Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus. | JuliΓ A et al. | β | 2018 | β |
| Genome-wide association study of developmental dysplasia of the hip identifies an association with <i>GDF5</i>. | Hatzikotoulas K et al. | β | 2018 | β |
| Genome-wide association study of offspring birth weight in 86β577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. | Beaumont RN et al. | β | 2018 | β |
| Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations. | Bonnemaijer PWM et al. | β | 2018 | β |
| Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients. | Taylor JC et al. | β | 2018 | β |
| Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis. | Massey J et al. | β | 2018 | β |
| Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study. | Loomis SJ et al. | β | 2018 | β |
| Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns. | Wahl A et al. | β | 2018 | β |
| Genome-Wide Association Study Reveals Genetic Link between Diarrhea-Associated Entamoeba histolytica Infection and Inflammatory Bowel Disease. | Wojcik GL et al. | β | 2018 | β |
| Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. | Klein AP et al. | β | 2018 | β |
| Genome-wide meta-analysis identifies novel loci associated with parathyroid hormone level. | Matana A et al. | β | 2018 | β |
| Genome-wide scan for commons SNPs affecting bovine leukemia virus infection level in dairy cattle. | Carignano HA et al. | β | 2018 | β |
| Genomic Analyses of Visual Cognition: Perceptual Rivalry and Top-Down Control. | Chen B et al. | β | 2018 | β |
| Genomic atlas of the human plasma proteome. | Sun BB et al. | β | 2018 | β |
| Genotype imputation for Han Chinese population using Haplotype Reference Consortium as reference. | Lin Y et al. | β | 2018 | β |
| Genotype Imputation from Large Reference Panels. | Das S et al. | β | 2018 | β |
| Haplotype phasing in single-cell DNA-sequencing data. | Satas G et al. | β | 2018 | β |
| Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins. | Liu H et al. | β | 2018 | β |
| High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability. | Palamara PF et al. | β | 2018 | β |
| Identification of Disease-Related Genes Using a Genome-Wide Association Study Approach. | Wohland T et al. | β | 2018 | β |
| Identification of <i>ST3AGL4</i>, <i>MFHAS1, CSNK2A2</i> and <i>CD226</i> as loci associated with systemic lupus erythematosus (SLE) and evaluation of SLE genetics in drug repositioning. | Wang YF et al. | β | 2018 | β |
| Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma. | Went M et al. | β | 2018 | β |
| IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis. | Arthur VL et al. | β | 2018 | β |
| Imputation-Aware Tag SNP Selection To Improve Power for Large-Scale, Multi-ethnic Association Studies. | Wojcik GL et al. | β | 2018 | β |
| Integrating genome-wide association study, chromosomal enhancer maps and element-gene interaction networks detected brain regions related associations between elements and ADHD/IQ. | Ma M et al. | β | 2018 | β |
| Integration of Murine and Human Studies for Mapping Periodontitis Susceptibility. | Nashef A et al. | β | 2018 | β |
| Joint analysis of multiple phenotypes in association studies using allele-based clustering approach for non-normal distributions. | Liang X et al. | β | 2018 | β |
| Leveraging putative enhancer-promoter interactions to investigate two-way epistasis in Type 2 Diabetes GWAS. | Manduchi E et al. | β | 2018 | β |
| LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins. | Wei WQ et al. | β | 2018 | β |
| Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study. | Christen T et al. | β | 2018 | β |
| Meta-analysis of exome array data identifies six novel genetic loci for lung function. | Jackson VE et al. | β | 2018 | β |
| Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity. | Edwards AC et al. | β | 2018 | β |
| Missing single nucleotide polymorphisms in Genetic Risk Scores: A simulation study. | Chagnon M et al. | β | 2018 | β |
| Multi-ethnic genome-wide association study for atrial fibrillation. | Roselli C et al. | β | 2018 | β |
| Multi-level genomic analyses suggest new genetic variants involved in human memory. | Zhu Z et al. | β | 2018 | β |
| Nature vs. nurture in human sociality: multi-level genomic analyses of social conformity. | Chen B et al. | β | 2018 | β |
| Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables. | Ahlqvist E et al. | β | 2018 | β |
| Novel Susceptibility Loci for Moyamoya Disease Revealed by a Genome-Wide Association Study. | Duan L et al. | β | 2018 | β |
| On the Null Distribution of Bayes Factors in Linear Regression. | Zhou Q et al. | β | 2018 | β |
| PhenotypeSimulator: A comprehensive framework for simulating multi-trait, multi-locus genotype to phenotype relationships. | Meyer HV et al. | β | 2018 | β |
| PLINK: Key Functions for Data Analysis. | Slifer SH | β | 2018 | β |
| Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer's disease. | Winchester LM et al. | β | 2018 | β |
| Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4. | Gilchrist JJ et al. | β | 2018 | β |
| Sex differences in body fat distribution are related to sex differences in serum leptin and adiponectin. | Christen T et al. | β | 2018 | β |
| Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. | Ostrom QT et al. | β | 2018 | β |
| Simulating variance heterogeneity in quantitative genome wide association studies. | Al Kawam A et al. | β | 2018 | β |
| Targeted resequencing of a locus for heparin-induced thrombocytopenia on chromosome 5 identified in a genome-wide association study. | Witten A et al. | β | 2018 | β |
| The Autoimmune-Associated Single Nucleotide Polymorphism Within <i>PTPN22</i> Correlates With Clinical Outcome After Lung Transplantation. | Budding K et al. | β | 2018 | β |
| The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5Β years of age. | Inshaw JRJ et al. | β | 2018 | β |
| The First Norovirus Longitudinal Seroepidemiological Study From Sub-Saharan Africa Reveals High Seroprevalence of Diverse Genotypes Associated With Host Susceptibility Factors. | Thorne L et al. | β | 2018 | β |
| The genetics of smoking in individuals with chronic obstructive pulmonary disease. | Obeidat M et al. | β | 2018 | β |
| The intragenic epistatic association of <i>ADD3</i> with biliary atresia in Southern Han Chinese population. | Wang Z et al. | β | 2018 | β |
| Transethnic and race-stratified genome-wide association study of fibroid characteristics in African American and European American women. | Bray MJ et al. | β | 2018 | β |
| Trans-Ethnic Polygenic Analysis Supports Genetic Overlaps of Lumbar Disc Degeneration With Height, Body Mass Index, and Bone Mineral Density. | Zhou X et al. | β | 2018 | β |
| Validation of genotype imputation in Southeast Asian populations and the effect of single nucleotide polymorphism annotation on imputation outcome. | Lert-Itthiporn W et al. | β | 2018 | β |
| Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer. | Loveday C et al. | β | 2018 | β |
| Validation of the novel susceptibility loci for prostate cancer in a Chinese population. | Wu Y et al. | β | 2018 | β |
| Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth. | Huusko JM et al. | β | 2018 | β |
| 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. | Gorski M et al. | β | 2017 | β |
| 10 Years of GWAS Discovery: Biology, Function, and Translation. | Visscher PM et al. | β | 2017 | β |
| A common genetic variant in FOXP2 is associated with language-based learning (dis)abilities: Evidence from two Italian independent samples. | Mozzi A et al. | β | 2017 | β |
| A comparison of different algorithms for phasing haplotypes using Holstein cattle genotypes and pedigree data. | Miar Y et al. | β | 2017 | β |
| Admixture mapping of pelvic organ prolapse in African Americans from the Women's Health Initiative Hormone Therapy trial. | Giri A et al. | β | 2017 | β |
| African genetic ancestry interacts with body mass index to modify risk for uterine fibroids. | Giri A et al. | β | 2017 | β |
| A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). | Na R et al. | β | 2017 | β |
| A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis. | Munz M et al. | β | 2017 | β |
| A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1. | Vijayakrishnan J et al. | β | 2017 | β |
| A genome-wide association study links small-vessel ischemic stroke to autophagy. | Lee TH et al. | β | 2017 | β |
| A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis. | Ng M et al. | β | 2017 | β |
| A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents. | Nielsen TR et al. | β | 2017 | β |
| A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model. | Nassan M et al. | β | 2017 | β |
| A genome-wide association study yields five novel thyroid cancer risk loci. | Gudmundsson J et al. | β | 2017 | β |
| A haplotype block downstream of plasminogen is associated with chronic and aggressive periodontitis. | Munz M et al. | β | 2017 | β |
| A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. | Manning A et al. | β | 2017 | β |
| A meta-analysis of reflux genome-wide association studies in 6750 Northern Europeans from the general population. | Bonfiglio F et al. | β | 2017 | β |
| A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis. | Saxena R et al. | β | 2017 | β |
| A multi-stage genome-wide association study of uterine fibroids in African Americans. | Hellwege JN et al. | β | 2017 | β |
| A Scalable Bayesian Method for Integrating Functional Information in Genome-wide Association Studies. | Yang J et al. | β | 2017 | β |
| Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. | Spracklen CN et al. | β | 2017 | β |
| Association between a Single Donor <i>TARC/CCL17</i> Promotor Polymorphism and Obstructive Chronic Lung Allograft Dysfunction after Lung Transplantation. | Budding K et al. | β | 2017 | β |
| BAYESIAN LARGE-SCALE MULTIPLE REGRESSION WITH SUMMARY STATISTICS FROM GENOME-WIDE ASSOCIATION STUDIES. | Zhu X et al. | β | 2017 | β |
| Chromosome contacts in activated T cells identify autoimmune disease candidate genes. | Burren OS et al. | β | 2017 | β |
| Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study. | Mhatre S et al. | β | 2017 | β |
| Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk. | Chang X et al. | β | 2017 | β |
| Common variants in ZMIZ1 and near NGF confer risk for primary dysmenorrhoea. | Li Z et al. | β | 2017 | β |
| Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma. | McDaniel LD et al. | β | 2017 | β |
| Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. | Guo MH et al. | β | 2017 | β |
| Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population. | Ferraz-Amaro I et al. | β | 2017 | β |
| Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. | Benyamin B et al. | β | 2017 | β |
| Dense genotyping of immune-related loci implicates host responses to microbial exposure in BehΓ§et's disease susceptibility. | Takeuchi M et al. | β | 2017 | β |
| Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. | Hu Y et al. | β | 2017 | β |
| Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies. | Hedman Γ K et al. | β | 2017 | β |
| Evaluation of Genetic Predisposition for MYCN-Amplified Neuroblastoma. | Hungate EA et al. | β | 2017 | β |
| Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus. | Hackinger S et al. | β | 2017 | β |
| Evaluation of the genetic basis of primary hypoadrenocorticism in Standard Poodles using SNP array genotyping and whole-genome sequencing. | Friedenberg SG et al. | β | 2017 | β |
| Evidence-based prioritisation and enrichment of genes interacting with metformin in type 2 diabetes. | Dawed AY et al. | β | 2017 | β |
| Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations. | Olafsson S et al. | β | 2017 | β |
| Gene-based genome-wide association study identified 19p13.3 for lean body mass. | Ran S et al. | β | 2017 | β |
| GeneImp: Fast Imputation to Large Reference Panels Using Genotype Likelihoods from Ultralow Coverage Sequencing. | Spiliopoulou A et al. | β | 2017 | β |
| Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p'-dde levels in a population-based sample. | Lind L et al. | β | 2017 | β |
| Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2. | Studd JB et al. | β | 2017 | β |
| Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications. | Ombrello MJ et al. | β | 2017 | β |
| Genetic association, mRNA and protein expression analysis identify ATG4C as a susceptibility gene for Kashin-Beck disease. | Wu C et al. | β | 2017 | β |
| Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. | Clay-Gilmour AI et al. | β | 2017 | β |
| Genetic Characterization and Influence on Inflammatory Bowel Disease Expression in a Diverse Hispanic South Florida Cohort. | Damas OM et al. | β | 2017 | β |
| Genetic polymorphisms associated with pancreatic cancer survival: a genome-wide association study. | Tang H et al. | β | 2017 | β |
| Genetic prediction of male pattern baldness. | Hagenaars SP et al. | β | 2017 | β |
| Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism. | Li N et al. | β | 2017 | β |
| Genetic risk analysis of coronary artery disease in Pakistani subjects using a genetic risk score of 21 variants. | Shahid SU et al. | β | 2017 | β |
| Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies. | Sekula P et al. | β | 2017 | β |
| Genetics of depressive symptoms in adolescence. | Sallis H et al. | β | 2017 | β |
| Genetics of neurodegenerative diseases: an overview. | PihlstrΓΈm L et al. | β | 2017 | β |
| Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study. | Allen RJ et al. | β | 2017 | β |
| Genetic variation associated with cardiovascular risk in autoimmune diseases. | Perrotti PP et al. | β | 2017 | β |
| Genetic variation in GABRΞ²1 and the risk for developing alcohol dependence. | McCabe WA et al. | β | 2017 | β |
| Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide. | Salvi E et al. | β | 2017 | β |
| Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits. | Lane JM et al. | β | 2017 | β |
| Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. | Li Z et al. | β | 2017 | β |
| Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. | Warren HR et al. | β | 2017 | β |
| Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia. | Law PJ et al. | β | 2017 | β |
| Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. | Law PJ et al. | β | 2017 | β |
| Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. | Hammerschlag AR et al. | β | 2017 | β |
| Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. | Sniekers S et al. | β | 2017 | β |
| Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study. | Parsa A et al. | β | 2017 | β |
| Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. | Ahola-Olli AV et al. | β | 2017 | β |
| Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia. | Han Y et al. | β | 2017 | β |
| Genome-wide association study identifies COL2A1 locus involved in the hand development failure of Kashin-Beck disease. | Hao J et al. | β | 2017 | β |
| Genome-wide association study identifies novel type II diabetes risk loci in Jordan subpopulations. | Dajani R et al. | β | 2017 | β |
| Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation. | Mullin BH et al. | β | 2017 | β |
| Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism. | Li M et al. | β | 2017 | β |
| Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. | Sud A et al. | β | 2017 | β |
| Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. | Melin BS et al. | β | 2017 | β |
| Genome-wide association study of immunoglobulin light chain amyloidosis in three patient cohorts: comparison with myeloma. | da Silva Filho MI et al. | β | 2017 | β |
| Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. | Ortega-Alonso A et al. | β | 2017 | β |
| Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1. | Smith AH et al. | β | 2017 | β |
| Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. | Uimari O et al. | β | 2017 | β |
| Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction. | Qian DC et al. | β | 2017 | β |
| Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus. | Schulz H et al. | β | 2017 | β |
| Genome-wide pathway analysis identifies VEGF pathway association with oral ulceration in systemic lupus erythematosus. | Aterido A et al. | β | 2017 | β |
| Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. | Graff M et al. | β | 2017 | β |
| GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians. | Nongmaithem SS et al. | β | 2017 | β |
| GW-SEM: A Statistical Package to Conduct Genome-Wide Structural Equation Modeling. | Verhulst B et al. | β | 2017 | β |
| Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis. | Wang L et al. | β | 2017 | β |
| Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. | Litchfield K et al. | β | 2017 | β |
| Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease. | Gallone G et al. | β | 2017 | β |
| Identifying genetic variants that affect viability in large cohorts. | Mostafavi H et al. | β | 2017 | β |
| Identifying pathways modulating sleep duration: from genomics to transcriptomics. | Allebrandt KV et al. | β | 2017 | β |
| Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels. | Zhou W et al. | β | 2017 | β |
| Imputation of missing genotypes within LD-blocks relying on the basic coalescent and beyond: consideration of population growth and structure. | Kabisch M et al. | β | 2017 | β |
| Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip Β± cleft palate and cleft palate only. | Ludwig KU et al. | β | 2017 | β |
| Inbred Strain Variant Database (ISVdb): A Repository for Probabilistically Informed Sequence Differences Among the Collaborative Cross Strains and Their Founders. | Oreper D et al. | β | 2017 | β |
| Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia. | Gu F et al. | β | 2017 | β |
| In Retrospect: A decade of shared genomic associations. | Manolio TA | β | 2017 | β |
| Integrating Genome-Wide Association and eQTLs Studies Identifies the Genes and Gene Sets Associated with Diabetes. | Liang X et al. | β | 2017 | β |
| Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma. | Hulur I et al. | β | 2017 | β |
| Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. | Lotta LA et al. | β | 2017 | β |
| Interaction between Single Nucleotide Polymorphism and Urinary Sodium, Potassium, and Sodium-Potassium Ratio on the Risk of Hypertension in Korean Adults. | Park YM et al. | β | 2017 | β |
| Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14. | Takahashi Y et al. | β | 2017 | β |
| Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. | McKay JD et al. | β | 2017 | β |
| Large-scale replication study identified multiple independent SNPs in <i>RET</i> synergistically associated with Hirschsprung disease in Southern Chinese population. | Zhang Y et al. | β | 2017 | β |
| Lessons from ten years of genome-wide association studies of asthma. | Vicente CT et al. | β | 2017 | β |
| Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. | Manousaki D et al. | β | 2017 | β |
| MARV: a tool for genome-wide multi-phenotype analysis of rare variants. | Kaakinen M et al. | β | 2017 | β |
| Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism. | Sapkota Y et al. | β | 2017 | β |
| Meta-analysis of genome-wide association studies identifies three novel loci for saturated fatty acids in East Asians. | Zhu J et al. | β | 2017 | β |
| Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors. | Mahmoudpour SH et al. | β | 2017 | β |
| miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. | Peng C et al. | β | 2017 | β |
| Molecular genetic contributions to self-rated health. | Harris SE et al. | β | 2017 | β |
| Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students. | Webb BT et al. | β | 2017 | β |
| Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation. | Shen X et al. | β | 2017 | β |
| Neuroblastoma survivors are at increased risk for second malignancies: A report from the International Neuroblastoma Risk Group Project. | Applebaum MA et al. | β | 2017 | β |
| New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475β000 Individuals. | Kraja AT et al. | β | 2017 | β |
| Niche harmony search algorithm for detecting complex disease associated high-order SNP combinations. | Tuo S et al. | β | 2017 | β |
| Nonsteroidal Anti-inflammatory Drug Interaction with Prostacyclin Synthase Protects from Miscarriage. | Velez Edwards DR et al. | β | 2017 | β |
| -Omic and Electronic Health Record Big Data Analytics for Precision Medicine. | Wu PY et al. | β | 2017 | β |
| Pathway analysis of complex diseases for GWAS, extending to consider rare variants, multi-omics and interactions. | Kao PY et al. | β | 2017 | β |
| Polygenic risk for five psychiatric disorders and cross-disorder and disorder-specific neural connectivity in two independent populations. | Wang T et al. | β | 2017 | β |
| Polygenic risk score analysis of pathologically confirmed Alzheimer disease. | Escott-Price V et al. | β | 2017 | β |
| Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies. | Tamm R et al. | β | 2017 | β |
| Potential Susceptibility Loci Identified for Renal Cell Carcinoma by Targeting Obesity-Related Genes. | Shu X et al. | β | 2017 | β |
| Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve. | Yang B et al. | β | 2017 | β |
| Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1. | Pasutto F et al. | β | 2017 | β |
| Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis. | Panoutsopoulou K et al. | β | 2017 | β |
| Reclassification of prostate cancer risk using sequentially identified SNPs: Results from the REDUCE trial. | Chen H et al. | β | 2017 | β |
| Reproductive fitness and genetic risk of psychiatric disorders in the general population. | Mullins N et al. | β | 2017 | β |
| Securing the use of existing sample collections for future human genetic research. | Kanoungi G et al. | β | 2017 | β |
| Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. | Flannick J et al. | β | 2017 | β |
| Sequence variant at 4q25 near PITX2 associates with appendicitis. | Kristjansson RP et al. | β | 2017 | β |
| Set-Based Tests for the Gene-Environment Interaction in Longitudinal Studies. | He Z et al. | β | 2017 | β |
| Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development. | Stergiakouli E et al. | β | 2017 | β |
| SNP-SNP interactions between WNT4 and WNT5A were associated with obesity related traits in Han Chinese Population. | Dong SS et al. | β | 2017 | β |
| Statistical methods to detect pleiotropy in human complex traits. | Hackinger S et al. | β | 2017 | β |
| Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation. | Obeidat M et al. | β | 2017 | β |
| The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma. | Capasso M et al. | β | 2017 | β |
| The genetic component of bicuspid aortic valve and aortic dilation. An exome-wide association study. | Gago-DΓaz M et al. | β | 2017 | β |
| The impact of rare and low-frequency genetic variants in common disease. | Bomba L et al. | β | 2017 | β |
| The Molecular Revolution in Cutaneous Biology: The Era of Genome-Wide Association Studies and Statistical, BigΒ Data, and Computational Topics. | Anbunathan H et al. | β | 2017 | β |
| The PF4/PPBP/CXCL5 Gene Cluster Is Associated with Periodontitis. | Shusterman A et al. | β | 2017 | β |
| The possible role of chromosome X variability in hypertensive familiarity. | Ciccarelli M et al. | β | 2017 | β |
| The utility of empirically assigning ancestry groups in cross-population genetic studies of addiction. | Peterson RE et al. | β | 2017 | β |
| Whole genome characterization of sequence diversity of 15,220 Icelanders. | JΓ³nsson H et al. | β | 2017 | β |
| Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. | Tachmazidou I et al. | β | 2017 | β |
| A Clustered Multiclass Likelihood-Ratio Ensemble Method for Family-Based Association Analysis Accounting for Phenotypic Heterogeneity. | Wen Y et al. | β | 2016 | β |
| A combined reference panel from the 1000βGenomes and UK10K projects improved rare variant imputation in European and Chinese samples. | Chou WC et al. | β | 2016 | β |
| A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding. | Painter JN et al. | β | 2016 | β |
| A computational method for genotype calling in family-based sequencing data. | Chang LC et al. | β | 2016 | β |
| A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer. | Scarbrough PM et al. | β | 2016 | β |
| A family-based study of gene variants and maternal folate and choline in neuroblastoma: a report from the Children's Oncology Group. | Mazul AL et al. | β | 2016 | β |
| Age at menarche and age at natural menopause in East Asian women: a genome-wide association study. | Shi J et al. | β | 2016 | β |
| A genome-wide association meta-analysis on apolipoprotein A-IV concentrations. | Lamina C et al. | β | 2016 | β |
| A Genome-Wide Association Study Identifies a Novel Locus for Bortezomib-Induced Peripheral Neuropathy in European Patients with Multiple Myeloma. | Magrangeas F et al. | β | 2016 | β |
| A Genome-Wide Association Study of Attention Function in a Population-Based Sample of Children. | Alemany S et al. | β | 2016 | β |
| A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy. | Wang Z et al. | β | 2016 | β |
| A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci. | Rand KA et al. | β | 2016 | β |
| An Adaptive Fisher's Combination Method for Joint Analysis of Multiple Phenotypes in Association Studies. | Liang X et al. | β | 2016 | β |
| Analysis of Genotyping-by-Sequencing (GBS) Data. | Kagale S et al. | β | 2016 | β |
| A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients. | Ulveling D et al. | β | 2016 | β |
| An Overview of Genome-Wide Association Studies in Alzheimer's Disease. | Shen L et al. | β | 2016 | β |
| Application of computational methods in genetic study of inflammatory bowel disease. | Li J et al. | β | 2016 | β |
| A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences. | Thorgeirsson TE et al. | β | 2016 | β |
| A reference panel of 64,976 haplotypes for genotype imputation. | McCarthy S et al. | β | 2016 | β |
| Ascertainment bias from imputation methods evaluation in wheat. | Brandariz SP et al. | β | 2016 | β |
| Association of Forced Vital Capacity with the Developmental Gene NCOR2. | Minelli C et al. | β | 2016 | β |
| Association of kidney structure-related gene variants with type 2 diabetes-attributed end-stage kidney disease in African Americans. | Guan M et al. | β | 2016 | β |
| Association of PNPLA3 rs738409 and TM6SF2 rs58542926 with health services utilization in a population-based study. | KΓΆpp J et al. | β | 2016 | β |
| Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study. | Ong JS et al. | β | 2016 | β |
| A thrifty variant in CREBRF strongly influences body mass index in Samoans. | Minster RL et al. | β | 2016 | β |
| A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology. | Hungate EA et al. | β | 2016 | β |
| Bias Characterization in Probabilistic Genotype Data and Improved Signal Detection with Multiple Imputation. | Palmer C et al. | β | 2016 | β |
| Calibration plot for proteomics: A graphical tool to visually check the assumptions underlying FDR control in quantitative experiments. | Giai Gianetto Q et al. | β | 2016 | β |
| Collapsed methylation quantitative trait loci analysis for low frequency and rare variants. | Richardson TG et al. | β | 2016 | β |
| Comparing performance of modern genotype imputation methods in different ethnicities. | Roshyara NR et al. | β | 2016 | β |
| CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk. | Garcia-Albeniz X et al. | β | 2016 | β |
| DNA methylation patterns associated with oxidative stress in an ageing population. | Hedman Γ K et al. | β | 2016 | β |
| Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder. | Luo X et al. | β | 2016 | β |
| Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes. | Kelleher J et al. | β | 2016 | β |
| Environmental Correlation Analysis for Genes Associated with Protection against Malaria. | Mackinnon MJ et al. | β | 2016 | β |
| Epigenetic and genetic components of height regulation. | Benonisdottir S et al. | β | 2016 | β |
| Epigenomic elements analyses for promoters identify ESRRG as a new susceptibility gene for obesity-related traits. | Dong SS et al. | β | 2016 | β |
| Erratum. | β | β | 2016 | β |
| Evaluation of voltage-dependent calcium channel Ξ³ gene families identified several novel potential susceptible genes to schizophrenia. | Guan F et al. | β | 2016 | β |
| Exome-Wide Association Analysis of Coronary Artery Disease in the Kingdom of Saudi Arabia Population. | de Kovel CG et al. | β | 2016 | β |
| Fast and accurate long-range phasing in a UK Biobank cohort. | Loh PR et al. | β | 2016 | β |
| Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy. | Sun Y et al. | β | 2016 | β |
| Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. | Vigorito E et al. | β | 2016 | β |
| Five endometrial cancer risk loci identified through genome-wide association analysis. | Cheng TH et al. | β | 2016 | β |
| Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression. | Hoskins JW et al. | β | 2016 | β |
| GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study. | Tin A et al. | β | 2016 | β |
| Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease. | Schott JM et al. | β | 2016 | β |
| Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations. | Lu X et al. | β | 2016 | β |
| Genetic variants in RBFOX3 are associated with sleep latency. | Amin N et al. | β | 2016 | β |
| Genome-wide analyses of aggressiveness in attention-deficit hyperactivity disorder. | Brevik EJ et al. | β | 2016 | β |
| Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank. | Lane JM et al. | β | 2016 | β |
| Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. | Zhang W et al. | β | 2016 | β |
| Genome-wide association studies and gene expression profiles of rheumatoid arthritis: An analysis. | Xiao X et al. | β | 2016 | β |
| Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene. | van Ingen G et al. | β | 2016 | β |
| Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. | Mitchell JS et al. | β | 2016 | β |
| Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers. | BornΓ© Y et al. | β | 2016 | β |
| Genome-wide association study in East Asians suggests UHMK1 as a novel bone mineral density susceptibility gene. | Choi HJ et al. | β | 2016 | β |
| Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112β151). | Davies G et al. | β | 2016 | β |
| Genome-wide association study of serum coenzyme Q10 levels identifies susceptibility loci linked to neuronal diseases. | Degenhardt F et al. | β | 2016 | β |
| Genome-wide meta-analyses identify novel loci associated with n-3 and n-6 polyunsaturated fatty acid levels in Chinese and European-ancestry populations. | Hu Y et al. | β | 2016 | β |
| Genome-Wide Meta-Analysis of Sciatica in Finnish Population. | LemmelΓ€ S et al. | β | 2016 | β |
| Genotype imputation in the domestic dog. | Friedenberg SG et al. | β | 2016 | β |
| Genotype Imputation with Millions of Reference Samples. | Browning BL et al. | β | 2016 | β |
| High rates of phasing errors in highly polymorphic species with low levels of linkage disequilibrium. | Bukowicki M et al. | β | 2016 | β |
| HLA-B*38:02:01 predicts carbimazole/methimazole-induced agranulocytosis. | Cheung CL et al. | β | 2016 | β |
| Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia. | Vathipadiekal V et al. | β | 2016 | β |
| hVMAT2: A Target of Individualized Medication for Parkinson's Disease. | Xiong N et al. | β | 2016 | β |
| Identification of susceptibility gene associated with female primary SjΓΆgren's syndrome in Han Chinese by genome-wide association study. | Song IW et al. | β | 2016 | β |
| Identity-by-descent estimation with population- and pedigree-based imputation in admixed family data. | Saad M et al. | β | 2016 | β |
| Imputing Genotypes in Biallelic Populations from Low-Coverage Sequence Data. | Fragoso CA et al. | β | 2016 | β |
| Incorporating Functional Genomic Information in Genetic Association Studies Using an Empirical Bayes Approach. | Spencer AV et al. | β | 2016 | β |
| Integrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk. | Guo Y et al. | β | 2016 | β |
| Justification for setting the individual animal genotype call rate threshold at eighty-five percent. | Purfield DC et al. | β | 2016 | β |
| Limited Evidence for Association of Genome-Wide Schizophrenia Risk Variants on Cortical Neuroimaging Phenotypes. | Voineskos AN et al. | β | 2016 | β |
| Meta-Analysis of Genome-Wide Association Studies and Network Analysis-Based Integration with Gene Expression Data Identify New Suggestive Loci and Unravel a Wnt-Centric Network Associated with Dupuytren's Disease. | Becker K et al. | β | 2016 | β |
| Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer. | Kerns SL et al. | β | 2016 | β |
| Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. | Postmus I et al. | β | 2016 | β |
| Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. | Below JE et al. | β | 2016 | β |
| Na Li and Matthew Stephens on Modeling Linkage Disequilibrium. | Song YS | β | 2016 | β |
| Next-generation genotype imputation service and methods. | Das S et al. | β | 2016 | β |
| Novel loci and pathways significantly associated with longevity. | Zeng Y et al. | β | 2016 | β |
| Novel susceptibility gene for nonfamilial hypokalemic periodic paralysis. | Song IW et al. | β | 2016 | β |
| ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase. | Zhakupova A et al. | β | 2016 | β |
| Physical and neurobehavioral determinants of reproductive onset and success. | Day FR et al. | β | 2016 | β |
| PPARGC1B gene is associated with Kashin-Beck disease in Han Chinese. | Wen Y et al. | β | 2016 | β |
| Prediction of male-pattern baldness from genotypes. | Liu F et al. | β | 2016 | β |
| Prevalence and determinants of periodic limb movements in the general population. | Haba-Rubio J et al. | β | 2016 | β |
| Rapid genotype refinement for whole-genome sequencing data using multi-variate normal distributions. | Arthur R et al. | β | 2016 | β |
| Rare variants in BRCA2 and CHEK2 are associated with the risk of urinary tract cancers. | Ge Y et al. | β | 2016 | β |
| Recurring exon deletions in the HP (haptoglobin) gene contribute to lower blood cholesterol levels. | Boettger LM et al. | β | 2016 | β |
| Relevance of the COPI complex for Alzheimer's disease progression in vivo. | Bettayeb K et al. | β | 2016 | β |
| Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study. | Lee YS et al. | β | 2016 | β |
| SparRec: An effective matrix completion framework of missing data imputation for GWAS. | Jiang B et al. | β | 2016 | β |
| Statistical Methods for Testing Genetic Pleiotropy. | Schaid DJ et al. | β | 2016 | β |
| Synaptotagmin XI in Parkinson's disease: New evidence from an association study in Spain and Mexico. | Sesar A et al. | β | 2016 | β |
| The genetic architecture of type 2 diabetes. | Fuchsberger C et al. | β | 2016 | β |
| Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21. | Zhang M et al. | β | 2016 | β |
| TNFRSF1B Is Associated with ANCA in IBD. | Li D et al. | β | 2016 | β |
| TNFSF10/TRAIL regulates human T4 effector memory lymphocyte radiosensitivity and predicts radiation-induced acute and subacute dermatitis. | Baijer J et al. | β | 2016 | β |
| Trans-ethnic meta-analysis of genome-wide association studies for Hirschsprung disease. | Tang CS et al. | β | 2016 | β |
| Trans-ethnic study design approaches for fine-mapping. | Asimit JL et al. | β | 2016 | β |
| Two-stage additional evidence support association of common variants in the HDAC3 with the increasing risk of schizophrenia susceptibility. | Jia X et al. | β | 2016 | β |
| Two-stage replication of previous genome-wide association studies of AS3MT-CNNM2-NT5C2 gene cluster region in a large schizophrenia case-control sample from Han Chinese population. | Guan F et al. | β | 2016 | β |
| Utility of blood pressure genetic risk score in admixed Hispanic samples. | Beecham AH et al. | β | 2016 | β |
| Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease. | Orlando G et al. | β | 2016 | β |
| Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. | Zhou K et al. | β | 2016 | β |
| Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease. | Sasaki MM et al. | β | 2016 | β |
| A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population. | Dorajoo R et al. | β | 2015 | β |
| Association of ARNTL and PER1 genes with Parkinson's disease: a case-control study of Han Chinese. | Gu Z et al. | β | 2015 | β |
| BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders. | BrainSeq: A Human Brain Genomics Consortium. Electronic address: drweinberger@libd.org et al. | β | 2015 | β |
| Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study. | Hollensted M et al. | β | 2015 | β |
| Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease. | Won HH et al. | β | 2015 | β |
| Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. | Bentham J et al. | β | 2015 | β |
| Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. | Giri A et al. | β | 2015 | β |
| Genome-Wide Association Study of Staphylococcus aureus Carriage in a Community-Based Sample of Mexican-Americans in Starr County, Texas. | Brown EL et al. | β | 2015 | β |
| Genome-wide association study reveals two loci for serum magnesium concentrations in European-American children. | Chang X et al. | β | 2015 | β |
| M(3)-S: a genotype calling method incorporating information from samples with known genotypes. | Li G et al. | β | 2015 | β |
| Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. | Cheng TH et al. | β | 2015 | β |
| The role of common genetic variation in educational attainment and income: evidence from the National Child Development Study. | Davies NM et al. | β | 2015 | β |
| Two-stage comprehensive evaluation of genetic susceptibility of common variants in FBXO38, AP3B2 and WHAMM to severe chronic periodontitis. | Shang D et al. | β | 2015 | β |