Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

paper Cited Public

Authors: Cross-Disorder Group of the Psychiatric Genomics Consortium; Lee, S Hong; Ripke, Stephan; Neale, Benjamin M; Faraone, Stephen V; Purcell, Shaun M; Perlis, Roy H; Mowry, Bryan J; Thapar, Anita; Goddard, Michael E; Witte, John S; Absher, Devin; Agartz, Ingrid; Akil, Huda; Amin, Farooq; Andreassen, Ole A; Anjorin, Adebayo; Anney, Richard; Anttila, Verneri; Arking, Dan E; Asherson, Philip; Azevedo, Maria H; Backlund, Lena; Badner, Judith A; Bailey, Anthony J; Banaschewski, Tobias; Barchas, Jack D; Barnes, Michael R; Barrett, Thomas B; Bass, Nicholas; Battaglia, Agatino; Bauer, Michael; Bayés, Mònica; Bellivier, Frank; Bergen, Sarah E; Berrettini, Wade; Betancur, Catalina; Bettecken, Thomas; Biederman, Joseph; Binder, Elisabeth B; Black, Donald W; Blackwood, Douglas H R; Bloss, Cinnamon S; Boehnke, Michael; Boomsma, Dorret I; Breen, Gerome; Breuer, René; Bruggeman, Richard; Cormican, Paul; Buccola, Nancy G; Buitelaar, Jan K; Bunney, William E; Buxbaum, Joseph D; Byerley, William F; Byrne, Enda M; Caesar, Sian; Cahn, Wiepke; Cantor, Rita M; Casas, Miguel; Chakravarti, Aravinda; Chambert, Kimberly; Choudhury, Khalid; Cichon, Sven; Cloninger, C Robert; Collier, David A; Cook, Edwin H; Coon, Hilary; Cormand, Bru; Corvin, Aiden; Coryell, William H; Craig, David W; Craig, Ian W; Crosbie, Jennifer; Cuccaro, Michael L; Curtis, David; Czamara, Darina; Datta, Susmita; Dawson, Geraldine; Day, Richard; De Geus, Eco J; Degenhardt, Franziska; Djurovic, Srdjan; Donohoe, Gary J; Doyle, Alysa E; Duan, Jubao; Dudbridge, Frank; Duketis, Eftichia; Ebstein, Richard P; Edenberg, Howard J; Elia, Josephine; Ennis, Sean; Etain, Bruno; Fanous, Ayman; Farmer, Anne E; Ferrier, I Nicol; Flickinger, Matthew; Fombonne, Eric; Foroud, Tatiana; Frank, Josef; Franke, Barbara; Fraser, Christine; Freedman, Robert; Freimer, Nelson B; Freitag, Christine M; Friedl, Marion; Frisén, Louise; Gallagher, Louise; Gejman, Pablo V; Georgieva, Lyudmila; Gershon, Elliot S; Geschwind, Daniel H; Giegling, Ina; Gill, Michael; Gordon, Scott D; Gordon-Smith, Katherine; Green, Elaine K; Greenwood, Tiffany A; Grice, Dorothy E; Gross, Magdalena; Grozeva, Detelina; Guan, Weihua; Gurling, Hugh; De Haan, Lieuwe; Haines, Jonathan L; Hakonarson, Hakon; Hallmayer, Joachim; Hamilton, Steven P; Hamshere, Marian L; Hansen, Thomas F; Hartmann, Annette M; Hautzinger, Martin; Heath, Andrew C; Henders, Anjali K; Herms, Stefan; Hickie, Ian B; Hipolito, Maria; Hoefels, Susanne; Holmans, Peter A; Holsboer, Florian; Hoogendijk, Witte J; Hottenga, Jouke-Jan; Hultman, Christina M; Hus, Vanessa; Ingason, Andrés; Ising, Marcus; Jamain, Stéphane; Jones, Edward G; Jones, Ian; Jones, Lisa; Tzeng, Jung-Ying; Kähler, Anna K; Kahn, René S; Kandaswamy, Radhika; Keller, Matthew C; Kennedy, James L; Kenny, Elaine; Kent, Lindsey; Kim, Yunjung; Kirov, George K; Klauck, Sabine M; Klei, Lambertus; Knowles, James A; Kohli, Martin A; Koller, Daniel L; Konte, Bettina; Korszun, Ania; Krabbendam, Lydia; Krasucki, Robert; Kuntsi, Jonna; Kwan, Phoenix; Landén, Mikael; Långström, Niklas; Lathrop, Mark; Lawrence, Jacob; Lawson, William B; Leboyer, Marion; Ledbetter, David H; Lee, Phil H; Lencz, Todd; Lesch, Klaus-Peter; Levinson, Douglas F; Lewis, Cathryn M; Li, Jun; Lichtenstein, Paul; Lieberman, Jeffrey A; Lin, Dan-Yu; Linszen, Don H; Liu, Chunyu; Lohoff, Falk W; Loo, Sandra K; Lord, Catherine; Lowe, Jennifer K; Lucae, Susanne; MacIntyre, Donald J; Madden, Pamela A F; Maestrini, Elena; Magnusson, Patrik K E; Mahon, Pamela B; Maier, Wolfgang; Malhotra, Anil K; Mane, Shrikant M; Martin, Christa L; Martin, Nicholas G; Mattheisen, Manuel; Matthews, Keith; Mattingsdal, Morten; McCarroll, Steven A; McGhee, Kevin A; McGough, James J; McGrath, Patrick J; McGuffin, Peter; McInnis, Melvin G; McIntosh, Andrew; McKinney, Rebecca; McLean, Alan W; McMahon, Francis J; McMahon, William M; McQuillin, Andrew; Medeiros, Helena; Medland, Sarah E; Meier, Sandra; Melle, Ingrid; Meng, Fan; Meyer, Jobst; Middeldorp, Christel M; Middleton, Lefkos; Milanova, Vihra; Miranda, Ana; Monaco, Anthony P; Montgomery, Grant W; Moran, Jennifer L; Moreno-De-Luca, Daniel; Morken, Gunnar; Morris, Derek W; Morrow, Eric M; Moskvina, Valentina; Muglia, Pierandrea; Mühleisen, Thomas W; Muir, Walter J; Müller-Myhsok, Bertram; Murtha, Michael; Myers, Richard M; Myin-Germeys, Inez; Neale, Michael C; Nelson, Stan F; Nievergelt, Caroline M; Nikolov, Ivan; Nimgaonkar, Vishwajit; Nolen, Willem A; Nöthen, Markus M; Nurnberger, John I; Nwulia, Evaristus A; Nyholt, Dale R; O'Dushlaine, Colm; Oades, Robert D; Olincy, Ann; Oliveira, Guiomar; Olsen, Line; Ophoff, Roel A; Osby, Urban; Owen, Michael J; Palotie, Aarno; Parr, Jeremy R; Paterson, Andrew D; Pato, Carlos N; Pato, Michele T; Penninx, Brenda W; Pergadia, Michele L; Pericak-Vance, Margaret A; Pickard, Benjamin S; Pimm, Jonathan; Piven, Joseph; Posthuma, Danielle; Potash, James B; Poustka, Fritz; Propping, Peter; Puri, Vinay; Quested, Digby J; Quinn, Emma M; Ramos-Quiroga, Josep Antoni; Rasmussen, Henrik B; Raychaudhuri, Soumya; Rehnström, Karola; Reif, Andreas; Ribasés, Marta; Rice, John P; Rietschel, Marcella; Roeder, Kathryn; Roeyers, Herbert; Rossin, Lizzy; Rothenberger, Aribert; Rouleau, Guy; Ruderfer, Douglas; Rujescu, Dan; Sanders, Alan R; Sanders, Stephan J; Santangelo, Susan L; Sergeant, Joseph A; Schachar, Russell; Schalling, Martin; Schatzberg, Alan F; Scheftner, William A; Schellenberg, Gerard D; Scherer, Stephen W; Schork, Nicholas J; Schulze, Thomas G; Schumacher, Johannes; Schwarz, Markus; Scolnick, Edward; Scott, Laura J; Shi, Jianxin; Shilling, Paul D; Shyn, Stanley I; Silverman, Jeremy M; Slager, Susan L; Smalley, Susan L; Smit, Johannes H; Smith, Erin N; Sonuga-Barke, Edmund J S; St Clair, David; State, Matthew; Steffens, Michael; Steinhausen, Hans-Christoph; Strauss, John S; Strohmaier, Jana; Stroup, T Scott; Sutcliffe, James S; Szatmari, Peter; Szelinger, Szabocls; Thirumalai, Srinivasa; Thompson, Robert C; Todorov, Alexandre A; Tozzi, Federica; Treutlein, Jens; Uhr, Manfred; van den Oord, Edwin J C G; Van Grootheest, Gerard; Van Os, Jim; Vicente, Astrid M; Vieland, Veronica J; Vincent, John B; Visscher, Peter M; Walsh, Christopher A; Wassink, Thomas H; Watson, Stanley J; Weissman, Myrna M; Werge, Thomas; Wienker, Thomas F; Wijsman, Ellen M; Willemsen, Gonneke; Williams, Nigel; Willsey, A Jeremy; Witt, Stephanie H; Xu, Wei; Young, Allan H; Yu, Timothy W; Zammit, Stanley; Zandi, Peter P; Zhang, Peng; Zitman, Frans G; Zöllner, Sebastian; Devlin, Bernie; Kelsoe, John R; Sklar, Pamela; Daly, Mark J; O'Donovan, Michael C; Craddock, Nicholas; Sullivan, Patrick F; Smoller, Jordan W; Kendler, Kenneth S; Wray, Naomi R; International Inflammatory Bowel Disease Genetics Consortium (IIBDGC)
Year: 2013
Journal: Nature genetics
PMID: 23933821
DOI: 10.1038/ng.2711
PMCID: PMC3800159

Figure 1

Evidence for genome-wide pleiotropy between psychiatric disorders. Proportion of variance in liability (SNP-based heritability) and proportion of covariance in liability between disorder (SNP-based coheritability) for five major psychiatric disorders. The 95% error bars represent the estimates ± 1.96 s.e. SCZ, schizophrenia; MDD, major depressive disorder; BPD, bipolar disorder.

Figure 2

Genomic partitioning of SNP-based heritability and SNP-based coheritability by annotation. Shown is the proportion of SNPs attributable to genes in the CNS+ set (red), the proportion of SNP-based heritability attributable to SNPs in the CNS+ set (dark green), the proportion of SNP-based coheritability attributable to SNPs in the CNS+ set (light green) and the proportion of SNP-based heritability for Crohn’s disease attributed to SNPs in the CNS+ set (orange). The 95% error bars represent the estimates ± 1.96 s.e. ***P < 1 × 10−5 in a test of whether the proportion of heritability explained by SNPs was equal to the proportion of SNP for the CNS+ set.

Figure 3

SNP-based heritabilities and coheritabilities. (a) For each disorder, SNP-based heritabilities are estimated from univariate analyses of the full data set (dark green) or of sample subsets (red and pink bars). These heritabilities are also estimated from bivariate analyses in which different subsets of the same disorder comprise the two traits (blue). Test of the heterogeneity of estimates, P value for Cochran’s Q: schizophrenia, 0.3; bipolar disorder, 1 × 10−6; major depressive disorder, 4 × 10−3; ADHD, 9 × 10−6; ASD, 0.99; Higgins’ I2: schizophrenia, 21%; bipolar disorder, 86%; major depressive disorder, 71%; ADHD, 91%; ASD, 0%). (b) For comparison, the coheritabilities using the full data sets reported in Figure 1 are shown. (c) As a negative control, estimates of coheritabilities with Crohn’s disease, a disease not expected to be genetically related to psychiatric disorders, are shown. We estimated 95% error bars using ± 1.96 s.e.

#	Section	Preview
20	DISCUSSION	Our finding of a substantial rg SNP of +0.43 between schizophrenia and major depressive disorder is…
21	DISCUSSION	from living in a family environment that includes a severely ill family member. If replicated by…
22	DISCUSSION	Our results show a small but significant rg SNP value between schizophrenia and ASD. A lower genetic…
23	DISCUSSION	The lack of overlap between ADHD and ASD is unexpected and is not consistent with family and data…
24	DISCUSSION	manic symptoms than the other major bipolar disorder subtype) and an increased risk for bipolar…
25	DISCUSSION	Our results should be interpreted in the context of four potentially important methodological…
26	DISCUSSION	In summary, we report SNP-based heritabilities that are significantly greater than zero for all five…
27	ONLINE METHODS — Data and quality control	A summary of the data available for analysis is listed in Table 1 and comprise data used in the…
28	ONLINE METHODS — Data and quality control	In each analysis, individuals were excluded to ensure that all cases and controls were completely…
29	ONLINE METHODS — Linear mixed model for estimation of SNP-based heritability and coherit-ability	We used the methods presented in Lee et al.18,35. Briefly, we estimated the variance in case-control…
30	ONLINE METHODS — Linear mixed model for estimation of SNP-based heritability and coherit-ability	y=Xβ+g+e where y is a vector of case (y = 1) or control (y = 0) status (the observed scale), β is…
31	ONLINE METHODS — Linear mixed model for estimation of SNP-based heritability and coherit-ability	V(y)=V=Aσg2+Iσe2 where σg2 is additive genetic variance tagged by the SNPs, σe2 is error…
32	ONLINE METHODS — Linear mixed model for estimation of SNP-based heritability and coherit-ability	The bivariate analyses used a bivariate extension of equation (1) (ref. 20). The two traits were…
33	ONLINE METHODS — Disorder risk for the study-based population (disorder risk, K)	Estimates of hSNP2 and SNP-based coheritability from the linear model are on the case-control scale…
34	ONLINE METHODS — Genome-partitioning linear mixed model	We partitioned the variance explained by the SNPs in several ways. For example, for the univariate…
35	ONLINE METHODS — Genome-partitioning linear mixed model	y=Xβ+∑t=1ngt+e with
36	ONLINE METHODS — Genome-partitioning linear mixed model	V=∑t=1nAtσgt2+Iσe2 where n is the number of subsets from any non-overlapping partitioning of…
37	ONLINE METHODS — Genome-partitioning linear mixed model	aSome cohorts include cases and pseudocontrols, where pseudocontrols are the genomic complements of…
38	ONLINE METHODS — Genome-partitioning linear mixed model	bUsed in Figures 1 and 3 Supplementary Tables 1–8.

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A common neural signature between genetic and environmental risk for mental illness.	Vedechkina M et al.	—	2025	→
Allele-Specific Regulation of PAXIP1-AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice.	Ni C et al.	—	2025	→
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Atlas of Gray Matter Volume Differences Across Psychiatric Conditions: A Systematic Review With a Novel Meta-Analysis That Considers Co-Occurring Disorders.	Fortea L et al.	—	2025	→
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Bidirectional genetic overlap between psychiatric disorders and high-density lipoprotein cholesterol levels.	Li X et al.	—	2025	→
Circulating Blood-Based Proteins in Psychopathology and Cognition: A Mendelian Randomization Study.	Bhattacharyya U et al.	—	2025	→
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Effect of Parental-Child Age Gaps and Skipped-Generation Families on Comorbidities Related to Attention Deficit Hyperactivity Disorder: A Population-Based Case-Control Study.	Fan HC et al.	—	2025	→
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Exploring the implications of case selection methods for psychiatric molecular genetic studies.	Kendler KS et al.	—	2025	→
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Gaze behaviors during free viewing revealed differences in visual salience processing across four major psychiatric disorders: a mega-analysis study of 1012 individuals.	Miura K et al.	—	2025	→
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Genetic predisposition for negative affect predicts mental health burden during the COVID-19 pandemic.	Schowe AM et al.	—	2025	→
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Integrating Multi-Omics Summary Data Identifies Candidate Molecular Mechanisms for Major Depression.	Nisbet L et al.	—	2025	→
Leveraging multigenerational health data to enhance mental disorder risk prediction: a population-based cohort study.	Hamad AF et al.	—	2025	→
Leveraging pleiotropic clustering to address high proportion correlated horizontal pleiotropy in Mendelian randomization studies.	Tang B et al.	—	2025	→
Linking Genome-Wide Association Studies to Pharmacological Treatments for Psychiatric Disorders.	Arnatkeviciute A et al.	—	2025	→
Long-read sequencing reveals the RNA isoform repertoire of neuropsychiatric risk genes in human brain.	De Paoli-Iseppi R et al.	—	2025	→
<i>Parabacteroides</i> distinguishes bipolar disorder from schizophrenia: toward a microbial biomarker for differential diagnosis.	Majie W et al.	—	2025	→
Mapping the Landscape of Autism Research: A Scientometric Review (2011-2023).	Mahajan P et al.	—	2025	→
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Maternal perinatal depression and the risk of disruptive behavioural disorder symptoms among offspring: A systematic review and meta-analysis.	Tusa BS et al.	—	2025	→
Mendelian Randomization Analysis of the Possible Causal Relationships Between Neurodevelopment-Related Proteins and Bipolar Disorder.	Li Y et al.	—	2025	→
Multitrait Genetic Analysis Identifies Novel Pleiotropic Loci for Depression and Schizophrenia in East Asians.	Song Y et al.	—	2025	→
MUTATE: a human genetic atlas of multiorgan artificial intelligence endophenotypes using genome-wide association summary statistics.	Boquet-Pujadas A et al.	—	2025	→
Neurobiological Perturbations in Bipolar Disorder Compared With Schizophrenia: Evidence From Cell Cultures and Brain Organoids.	Akkouh IA et al.	—	2025	→
Parental kynurenine 3-monooxygenase genotype in mice directs sex-specific behavioral outcomes in offspring.	Milosavljevic S et al.	—	2025	→
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Precision Medicine in Pediatric Attention-deficit/Hyperactivity Disorder: A Systematic Review of Behavioral, Neurobiological and Genetic Diagnostic Biomarkers.	Pranjić M et al.	—	2025	→
Psychiatric Polygenic Risk Scores and Week-by-Week Symptomatic Status in Youth with Bipolar Disorder: An Exploratory Study.	Jiang X et al.	—	2025	→
Reduced Cacna1c Expression Produces Anhedonic Reactions to Palatable Sucrose in Rats: No Interactions With Juvenile or Adult Stress.	Gasalla P et al.	—	2025	→
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Severity of autism-related symptoms in treatment-resistant schizophrenia: associations with cognitive performance, psychosocial functioning, and neurological soft signs - Clinical evidence and ROC analysis.	Vellucci L et al.	—	2025	→
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The Balance in the Head: How Developmental Factors Explain Relationships Between Brain Asymmetries and Mental Diseases.	Manns M et al.	—	2025	→
The Genetic Architecture of Differentiating Behavioral and Emotional Problems in Early Life.	Askelund AD et al.	—	2025	→
The relationship between lifetime trauma exposure and psychosis in a multi-country case-control study in Africa.	Stevenson A et al.	—	2025	→
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Unraveling Attention-Deficit/Hyperactivity Disorder Etiology: Current Challenges and Future Directions in Treatment.	Poddar A et al.	—	2025	→
Unraveling the Shared Genetic Architecture and Polygenic Overlap Between Loneliness, Major Depressive Disorder, and Sleep-Related Traits.	Rehman Z et al.	—	2025	→
When the Structural, Social, and Biological Domains Converge: The Case of Neighborhood Ethnic Density and Psychosis.	Anglin DM et al.	—	2025	→
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A Computational Model for the Simulation of Prepulse Inhibition and Its Modulation by Cortical and Subcortical Units.	Bezerra TO et al.	—	2024	→
Advances in the understanding of the pathophysiology of schizophrenia and bipolar disorder through induced pluripotent stem cell models.	Perrottelli A et al.	—	2024	→
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A novel blood-based epigenetic biosignature in first-episode schizophrenia patients through automated machine learning.	Karaglani M et al.	—	2024	→
An updated review on animal models to study attention-deficit hyperactivity disorder.	Kim D et al.	—	2024	→
A Plea for Nuance: Should People with a Family History of Bipolar Disorder Be Excluded from Clinical Trials of Psilocybin Therapy?	Downey AE et al.	—	2024	→
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A Systematic Review and Meta-analysis of Parental Depression, Antidepressant Usage, Antisocial Personality Disorder, and Stress and Anxiety as Risk Factors for Attention-Deficit/Hyperactivity Disorder (ADHD) in Children.	Robinson LR et al.	—	2024	→
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Bipolar patients display stoichiometric imbalance of gene expression in post-mortem brain samples.	Holmgren A et al.	—	2024	→
Brain Functional Connectome Defines a Transdiagnostic Dimension Shared by Cognitive Function and Psychopathology in Preadolescents.	Xiao X et al.	—	2024	→
Categorical and Dimensional Approaches for Psychiatric Classification and Treatment Targeting: Considerations from Psychosis Biotypes.	Clementz BA et al.	—	2024	→
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Comprehensive Sex-Stratified Genetic Analysis of 28 Blood Biomarkers and Depression Reveals a Significant Association between Depression and Low Levels of Total Protein in Females.	Kiewa J et al.	—	2024	→
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Genetic overlap between schizophrenia spectrum disorders and Alzheimer's disease: Current evidence and future directions - An integrative review.	Ohi K et al.	—	2024	→
Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders.	Luo J et al.	—	2024	→
Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci.	Lori A et al.	—	2024	→
Genome-wide DNA methylation risk scores for schizophrenia derived from blood and brain tissues further explain the genetic risk in patients stratified by polygenic risk scores for schizophrenia and bipolar disorder.	Ohi K et al.	—	2024	→
HLA-A, -B, -C and -DRB1 Association with Autism Spectrum Disorder Risk: A Sex-Related Analysis in Italian ASD Children and Their Siblings.	Guerini FR et al.	—	2024	→
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Integrating Electronic Health Records and Polygenic Risk to Identify Genetically Unrelated Comorbidities of Schizophrenia That May Be Modifiable.	Vessels T et al.	—	2024	→
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TLR4 Polymorphisms (T399I/D299G) Association with Schizophrenia and Bipolar Disorder in a Tunisian Population.	Aflouk Y et al.	—	2024	→
Using the Bayesian variational spike and slab model in a genome-wide association study for finding associated loci with bipolar disorder.	Kazemi Naeini M et al.	—	2024	→
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Alteration of Gut Microbiome in Patients With Schizophrenia Indicates Links Between Bacterial Tyrosine Biosynthesis and Cognitive Dysfunction.	Thirion F et al.	—	2023	→
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Applying dimensional psychopathology: transdiagnostic prediction of executive cognition using brain connectivity and inflammatory biomarkers.	Wei Y et al.	—	2023	→
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Cannabis Use and Endocannabinoid Receptor Genes: A Pilot Study on Their Interaction on Brain Activity in First-Episode Psychosis.	Oscoz-Irurozqui M et al.	—	2023	→
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Evaluating 17 methods incorporating biological function with GWAS summary statistics to accelerate discovery demonstrates a tradeoff between high sensitivity and high positive predictive value.	Moore A et al.	—	2023	→
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Hunting for Genes Underlying Emotionality in the Laboratory Rat: Maps, Tools and Traps.	Ramos A et al.	—	2023	→
Identifying the mediating role of socioeconomic status on the relationship between schizophrenia and major depressive disorder: a Mendelian randomisation analysis.	Xu Q et al.	—	2023	→
<i>In silico</i> evaluation of the role of lisdexamfetamine on attention-deficit/hyperactivity disorder common psychiatric comorbidities: mechanistic insights on binge eating disorder and depression.	Gutiérrez-Casares JR et al.	—	2023	→
Immune synaptopathies: how maternal immune activation impacts synaptic function during development.	Matteoli M et al.	—	2023	→
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Insomnia and circadian rhythm: a bibliometrics study and visualization analysis <i>via</i> CiteSpace.	He QY et al.	—	2023	→
Leveraging Machine Learning for Gaining Neurobiological and Nosological Insights in Psychiatric Research.	Chen J et al.	—	2023	→
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Melatonin in Neurodevelopmental Disorders: A Critical Literature Review.	Feybesse C et al.	—	2023	→
Meta-analysis of personal and familial co-occurrence of Attention Deficit/Hyperactivity Disorder and Bipolar Disorder.	Khoury E et al.	—	2023	→
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A novel longitudinal clustering approach to psychopathology across diagnostic entities in the hospital-based PsyCourse study.	Schulte EC et al.	—	2022	→
A scoping review and comparison of approaches for measuring genetic heterogeneity in psychiatric disorders.	Wang H et al.	—	2022	→
Association and epistatic analysis of white matter related genes across the continuum schizophrenia and autism spectrum disorders: The joint effect of NRG1-ErbB genes.	Prats C et al.	—	2022	→
Association of <i>PPP1R1B</i> polymorphisms with working memory in healthy Han Chinese adults.	Ma H et al.	—	2022	→
Association of polygenic risk scores and hair cortisol with mental health trajectories during COVID lockdown.	Ahrens KF et al.	—	2022	→
A three-factor model of common early onset psychiatric disorders: temperament, adversity, and dopamine.	Iqbal M et al.	—	2022	→
Auditory processing in rodent models of autism: a systematic review.	Wilde M et al.	—	2022	→
Autism spectrum disorder and schizophrenia: An updated conceptual review.	Jutla A et al.	—	2022	→
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Bipolar-associated miR-499-5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2.	Martins HC et al.	—	2022	→
Brain-wide versus genome-wide vulnerability biomarkers for severe mental illnesses.	Kochunov P et al.	—	2022	→
Characterizing mood disorders in the AFFECT study: a large, longitudinal, and phenotypically rich genetic cohort in the US.	Dalby M et al.	—	2022	→
Circulating hsa-let-7e-5p and hsa-miR-125a-5p as Possible Biomarkers in the Diagnosis of Major Depression and Bipolar Disorders.	Gecys D et al.	—	2022	→
Circulating miRNAs as Potential Biomarkers for Patient Stratification in Bipolar Disorder: A Combined Review and Data Mining Approach.	Clausen AR et al.	—	2022	→
Cohort profile: the Swedish National Quality Register for bipolar disorder(BipoläR).	Pålsson E et al.	—	2022	→
Consensus on potential biomarkers developed for use in clinical tests for schizophrenia.	Lin P et al.	—	2022	→
Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology.	Ahmed M et al.	—	2022	→
Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study.	Kirschner M et al.	—	2022	→
CRISPR/Cas-Based Approaches to Study Schizophrenia and Other Neurodevelopmental Disorders.	Kurishev AO et al.	—	2022	→
Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings.	Cheon EJ et al.	—	2022	→
Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease.	Uellendahl-Werth F et al.	—	2022	→
Culture and psychopathology: An attempt at reconsidering the role of social learning.	Fonagy P et al.	—	2022	→
Diagnostic progression to schizophrenia: A nationwide cohort study of 11 170 adolescents and young adults with autism spectrum disorder.	Hsu TW et al.	—	2022	→
Early cognitive comorbidities before disease onset: A common symptom towards prevention of related brain diseases?	Chauvière L	—	2022	→
Embedded figures in schizophrenia: A main deficit but no specificity.	Favrod O et al.	—	2022	→
Epigenetic signatures relating to disease-associated genotypic burden in familial risk of bipolar disorder.	Hesam-Shariati S et al.	—	2022	→
Epigenome-wide DNA methylation analysis of whole blood cells derived from patients with GAD and OCD in the Chinese Han population.	Guo L et al.	—	2022	→
Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism.	Schendel D et al.	—	2022	→
Event-related potential correlates of affective response inhibition in bipolar I disorder: Comparison with schizophrenia.	Menkes MW et al.	—	2022	→
Factors Associated with Quality of Life in Relatives of Adults with Serious Mental Illness: A Systematic Review.	Lima-Rodríguez JS et al.	—	2022	→
Familial coaggregation of major psychiatric disorders in first-degree relatives of individuals with autism spectrum disorder: a nationwide population-based study.	Wang HE et al.	—	2022	→
[Family history of mood disorders may weaken the link between adverse childhood experience and suicidality in patients with depression].	Kibitov AA et al.	—	2022	→
From Genome-Wide to Environment-Wide: Capturing the Environome.	von Stumm S et al.	—	2022	→
Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale.	Hong JSW et al.	—	2022	→
Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis.	Grotzinger AD et al.	—	2022	→
Genetic Liabilities Differentiating Bipolar Disorder, Schizophrenia, and Major Depressive Disorder, and Phenotypic Heterogeneity in Bipolar Disorder.	Richards AL et al.	—	2022	→
Genome-Transcriptome-Functional Connectivity-Cognition Link Differentiates Schizophrenia From Bipolar Disorder.	Chen J et al.	—	2022	→
Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci.	Wiström ED et al.	—	2022	→
Genome-Wide Association Studies across Environmental and Genetic Contexts Reveal Complex Genetic Architecture of Symbiotic Extended Phenotypes.	Batstone RT et al.	—	2022	→
Genomics, convergent neuroscience and progress in understanding autism spectrum disorder.	Willsey HR et al.	—	2022	→
Genomic Strategies for Understanding the Pathophysiology of Autism Spectrum Disorder.	Doi M et al.	—	2022	→
Identifying pleiotropic genes for complex phenotypes with summary statistics from a perspective of composite null hypothesis testing.	Wang T et al.	—	2022	→
Identifying pleiotropic genes for major psychiatric disorders with GWAS summary statistics using multivariate adaptive association tests.	Wang Y et al.	—	2022	→
Identifying transdiagnostic biological subtypes across schizophrenia, bipolar disorder, and major depressive disorder based on lipidomics profiles.	Tao S et al.	—	2022	→
Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder.	de Zwarte SMC et al.	—	2022	→
Intranasal oxytocin administration impacts the acquisition and consolidation of trauma-associated memories: a double-blind randomized placebo-controlled experimental study in healthy women.	Schultebraucks K et al.	—	2022	→
Leveraging Gene-Level Prediction as Informative Covariate in Hypothesis Weighting Improves Power for Rare Variant Association Studies.	Ji Y et al.	—	2022	→
Linking cerebellar functional gradients to transdiagnostic behavioral dimensions of psychopathology.	Dong D et al.	—	2022	→
Longer screen time utilization is associated with the polygenic risk for Attention-deficit/hyperactivity disorder with mediation by brain white matter microstructure.	Yang A et al.	—	2022	→
Maternal pregnancy-related infections and autism spectrum disorder-the genetic perspective.	Nudel R et al.	—	2022	→
Mental Health Symptom Reduction Using Digital Therapeutics Care Informed by Genomic SNPs and Gut Microbiome Signatures.	Pedroso I et al.	—	2022	→
Molecular Characterisation of the Mechanism of Action of Stimulant Drugs Lisdexamfetamine and Methylphenidate on ADHD Neurobiology: A Review.	Quintero J et al.	—	2022	→
Novel disease associations with schizophrenia genetic risk revealed in ~400,000 UK Biobank participants.	Zhang R et al.	—	2022	→
Novel treatments for autism spectrum disorder based on genomics and systems biology.	Baribeau D et al.	—	2022	→
Paternal and maternal psychiatric disorders associated with offspring autism spectrum disorders: A case-control study.	Yu T et al.	—	2022	→
Personality traits differentiate patients with bipolar disorder and healthy controls - A meta-analytic approach.	Hanke N et al.	—	2022	→
Plasma circulating micro-RNAs associated with alexithymia reflect a high overlap on neuropsychiatric outcomes.	Van der Auwera S et al.	—	2022	→
Population-based genetic effects for developmental stuttering.	Polikowsky HG et al.	—	2022	→
Putting Genetics to Work in the Psychiatric Clinic.	McMahon FJ	—	2022	→
Quantifying concordant genetic effects of de novo mutations on multiple disorders.	Guo H et al.	—	2022	→
Rare diseases: human genome research is coming home.	Ropers HH et al.	—	2022	→
Reduced Gray Matter Volume in Orbitofrontal Cortex Across Schizophrenia, Major Depressive Disorder, and Bipolar Disorder: A Comparative Imaging Study.	Yang Y et al.	—	2022	→
Regulation of DNA Methylation by Cannabidiol and Its Implications for Psychiatry: New Insights from In Vivo and In Silico Models.	Domingos LB et al.	—	2022	→
Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression.	Li Y et al.	—	2022	→
Revisiting the seven pillars of RDoC.	Morris SE et al.	—	2022	→
Risk for Mood, Anxiety, and Psychotic Disorders in Individuals at High and Low Genetic Liability for Bipolar Disorder and Major Depression.	Kendler KS et al.	—	2022	→
Role of polygenic and environmental factors in the co-occurrence of depression and psychosis symptoms: a network analysis.	Garcia-Mondragon L et al.	—	2022	→
Schizophrenia and Bipolar Polygenic Risk Scores in Relation to Intracranial Volume.	de Zwarte SMC et al.	—	2022	→
Sex-heterogeneous SNPs disproportionately influence gene expression and health.	Traglia M et al.	—	2022	→
Shared and distinct patterns of atypical cortical morphometry in children with autism and anxiety.	Yin S et al.	—	2022	→
Shared brain and genetic architectures between mental health and physical activity.	Zhang W et al.	—	2022	→
Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multipopulation data sets.	Aoki R et al.	—	2022	→
Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications.	Jiang CC et al.	—	2022	→
Synthesis of genetic association studies on autism spectrum disorders using a genetic model-free approach.	Mpoulimari I et al.	—	2022	→
Systematic Review: Molecular Studies of Common Genetic Variation in Child and Adolescent Psychiatric Disorders.	Akingbuwa WA et al.	—	2022	→
The causal association between iron status and the risk of autism: A Mendelian randomization study.	Chen L et al.	—	2022	→
The central role of self-esteem in the quality of life of patients with mental disorders.	Barbalat G et al.	—	2022	→
The ESSENCE-Questionnaire in Medical Records Screening for Neurodevelopmental Symptoms/Problems: Utility and Clinical Validity.	Landgren V et al.	—	2022	→
The host genetics affects gut microbiome diversity in Chinese depressed patients.	Han K et al.	—	2022	→
The inferior frontal gyrus and familial risk for bipolar disorder.	Qin K et al.	—	2022	→
The Latent Structure of Negative Symptoms in the General Population in Adolescence and Emerging Adulthood.	Havers L et al.	—	2022	→
The Long Non-Coding RNA <i>GOMAFU</i> in Schizophrenia: Function, Disease Risk, and Beyond.	Zakutansky PM et al.	—	2022	→
The next 10 years of behavioural genomic research.	Plomin R	—	2022	→
The Role of Genetics, Epigenetics, and the Environment in ASD: A Mini Review.	Khogeer AA et al.	—	2022	→
The selfish environment meets the selfish gene: Coevolution and inheritance of RNA and DNA pools: A model for organismal life incorporating coevolution, horizontal transfer, and inheritance of internal and external RNA and DNA pools.: A model for organismal life incorporating coevolution, horizontal transfer, and inheritance of internal and external RNA and DNA pools.	Monaco AP	—	2022	→
Transfer Learning for High-Dimensional Linear Regression: Prediction, Estimation and Minimax Optimality.	Li S et al.	—	2022	→
Ultrarare Loss-of-Function Mutations in the Genes Encoding the Ionotropic Glutamate Receptors of Kainate Subtypes Associated with Schizophrenia Disrupt the Interaction with PSD95.	Hu TM et al.	—	2022	→
Using big data of genetics, health claims, and brain imaging to challenge the categorical classification in mental illness.	Su TP et al.	—	2022	→
Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach.	Cearns M et al.	—	2022	→
Visual masking deficits in schizophrenia: a view into the genetics of the disease through an endophenotype.	Shaqiri A et al.	—	2022	→
XPXP: improving polygenic prediction by cross-population and cross-phenotype analysis.	Xiao J et al.	—	2022	→
A Biased Perspective on Brain Imaging of ADHD.	Castellanos FX	—	2021	→
A comprehensive gene-centric pleiotropic association analysis for 14 psychiatric disorders with GWAS summary statistics.	Lu H et al.	—	2021	→
ADHD and offending.	Young S et al.	—	2021	→
Alcohol use disorders and ADHD.	Luderer M et al.	—	2021	→
Allele-specific DNA methylation maps in monozygotic twins discordant for psychiatric disorders reveal that disease-associated switching at the EIPR1 regulatory loci modulates neural function.	Li Q et al.	—	2021	→
American psychiatry in the new millennium: a critical appraisal.	Scull A	—	2021	→
A multi-site, multi-disorder resting-state magnetic resonance image database.	Tanaka SC et al.	—	2021	→
Analysis of genetic differences between psychiatric disorders: exploring pathways and cell types/tissues involved and ability to differentiate the disorders by polygenic scores.	Rao S et al.	—	2021	→
An epigenetic, transgenerational model of increased mental health disorders in children, adolescents and young adults.	Monaco AP	—	2021	→
A Next Generation Sequencing-Based Protocol for Screening of Variants of Concern in Autism Spectrum Disorder.	Huang J et al.	—	2021	→
An integrative analysis of genomic and exposomic data for complex traits and phenotypic prediction.	Zhou X et al.	—	2021	→
An investigation to choose the proper therapy technique in the management of autism spectrum disorder.	Ozsahin I et al.	—	2021	→
Application of Next-Generation Sequencing in Neurodegenerative Diseases: Opportunities and Challenges.	Shademan B et al.	—	2021	→
Are the 50's, the transition decade, in choroid plexus aging?	Tahira A et al.	—	2021	→
A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone.	North HF et al.	—	2021	→
Association Between Periconceptional Weight of Maternal Grandmothers and Attention-Deficit/Hyperactivity Disorder in Grandchildren.	Yim G et al.	—	2021	→
Association between perinatal depression and risk of attention deficit hyperactivity disorder among children: a retrospective cohort study.	Nidey NL et al.	—	2021	→
Association of etiological factors across the extreme end and continuous variation in disordered eating in female Swedish twins.	Dinkler L et al.	—	2021	→
Association of Maternal Depressive Symptoms During the Perinatal Period With Oppositional Defiant Disorder in Children and Adolescents.	Dachew BA et al.	—	2021	→
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.	Amare AT et al.	—	2021	→
A Systematic Review and Meta-Analysis of the Risk of Disruptive Behavioral Disorders in the Offspring of Parents with Severe Psychiatric Disorders.	Ayano G et al.	—	2021	→
Attention-deficit/hyperactivity disorder with developmental coordination disorder: 24-year follow-up of a population-based sample.	Landgren V et al.	—	2021	→
Bench Research Informed by GWAS Results.	Kondratyev NV et al.	—	2021	→
Biological implications of genetic variations in autism spectrum disorders from genomics studies.	Zhang Y et al.	—	2021	→
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.	Andlauer TFM et al.	—	2021	→
Bipolar women's antepartum psychotropic exposure and offspring risk of attention-deficit/hyperactivity disorder and autism spectrum disorder.	Yeh TC et al.	—	2021	→
Boosting heritability: estimating the genetic component of phenotypic variation with multiple sample splitting.	Mai TT et al.	—	2021	→
Brain Organoids: Filling the Need for a Human Model of Neurological Disorder.	Jalink P et al.	—	2021	→
Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking.	Hindley G et al.	—	2021	→
Combining multivariate genomic approaches to elucidate the comorbidity between autism spectrum disorder and attention deficit hyperactivity disorder.	Peyre H et al.	—	2021	→
Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.	Schubert KO et al.	—	2021	→
Combining Structural-Equation Modeling with Genomic-Relatedness-Matrix Restricted Maximum Likelihood in OpenMx.	Kirkpatrick RM et al.	—	2021	→
Common Brain Networks Between Major Depressive-Disorder Diagnosis and Symptoms of Depression That Are Validated for Independent Cohorts.	Yamashita A et al.	—	2021	→
Common genetic associations between age-related diseases.	Dönertaş HM et al.	—	2021	→
Comorbidity of ADHD and adult bipolar disorder: A systematic review and meta-analysis.	Schiweck C et al.	—	2021	→
Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications.	Delling JP et al.	—	2021	→
Comprehensive Integrative Analyses Identify TIGD5 rs75547282 as a Risk Variant for Autism Spectrum Disorder.	Xie X et al.	—	2021	→
Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders.	Byrne EM et al.	—	2021	→
Contextualizing genetic risk score for disease screening and rare variant discovery.	Zhou D et al.	—	2021	→
Copy Number Variants and Polygenic Risk Scores Predict Need of Care in Autism and/or ADHD Families.	LaBianca S et al.	—	2021	→
Could Polygenic Risk Scores Be Useful in Psychiatry?: A Review.	Murray GK et al.	—	2021	→
Cross-Disorder Genomics Data Analysis Elucidates a Shared Genetic Basis Between Major Depression and Osteoarthritis Pain.	Barowsky S et al.	—	2021	→
Decreased DNA methylation at promoters and gene-specific neuronal hypermethylation in the prefrontal cortex of patients with bipolar disorder.	Bundo M et al.	—	2021	→
De novo variation in bipolar disorder.	Goes FS et al.	—	2021	→
Detecting local genetic correlations with scan statistics.	Guo H et al.	—	2021	→
Developmental Profile of Psychiatric Risk Associated With Voltage-Gated Cation Channel Activity.	Clifton NE et al.	—	2021	→
Dissecting autism and schizophrenia through neuroimaging genomics.	Moreau CA et al.	—	2021	→
Dopamine in Autism Spectrum Disorders-Focus on D2/D3 Partial Agonists and Their Possible Use in Treatment.	Mandic-Maravic V et al.	—	2021	→
Early differences in auditory processing relate to Autism Spectrum Disorder traits in infants with Neurofibromatosis Type I.	Begum-Ali J et al.	—	2021	→
Effects of polygenic risk score, childhood trauma and resilience on depressive symptoms in Chinese adolescents in a three-year cohort study.	Shao N et al.	—	2021	→
Elevated C-reactive protein levels across diagnoses: The first comparison among inpatients with major depressive disorder, bipolar disorder, or obsessive-compulsive disorder.	Caldirola D et al.	—	2021	→
Environmental Influences Measured by Epigenetic Clock and Vulnerability Components at Birth Impact Clinical ASD Heterogeneity.	Neri de Souza Reis V et al.	—	2021	→
Environmental Risk Factors for Schizophrenia and Bipolar Disorder and Their Relationship to Genetic Risk: Current Knowledge and Future Directions.	Robinson N et al.	—	2021	→
Environmental Risk Factors in Bipolar Disorder and Psychotic Depression: A Systematic Review and Meta-Analysis of Prospective Studies.	Rodriguez V et al.	—	2021	→
Evolving Concepts of the Schizophrenia Spectrum: A Research Domain Criteria Perspective.	Cuthbert BN et al.	—	2021	→
Explaining the missing heritability of psychiatric disorders.	Owen MJ et al.	—	2021	→
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes.	Rødevand L et al.	—	2021	→
Family Genetic Risk Scores and the Genetic Architecture of Major Affective and Psychotic Disorders in a Swedish National Sample.	Kendler KS et al.	—	2021	→
Functional connectome-wide associations of schizophrenia polygenic risk.	Cao H et al.	—	2021	→
Future directions in personality pathology.	Fonagy P et al.	—	2021	→
Gene × environment interaction in major depressive disorder.	Zhao MZ et al.	—	2021	→
[Genetic Analyses of Complex Phenotypes Through the Example of Anorexia Nervosa and Bodyweight Regulation].	Hirtz R et al.	—	2021	→
Genetic architecture of autism spectrum disorder: Lessons from large-scale genomic studies.	Choi L et al.	—	2021	→
Genetic association of FMRP targets with psychiatric disorders.	Clifton NE et al.	—	2021	→
Genetic contributions to autism spectrum disorder.	Havdahl A et al.	—	2021	→
Genetic liability to schizophrenia is associated with exposure to traumatic events in childhood.	Sallis HM et al.	—	2021	→
Genetic loci shared between major depression and intelligence with mixed directions of effect.	Bahrami S et al.	—	2021	→
Genetic risk for bipolar disorder and schizophrenia predicts structure and function of the ventromedial prefrontal cortex.	Abé C et al.	—	2021	→
Genetic susceptibility for major depressive disorder associates with trajectories of depressive symptoms across childhood and adolescence.	Lussier AA et al.	—	2021	→
Genetic variants in the bipolar disorder risk locus SYNE1 that affect CPG2 expression and protein function.	Rathje M et al.	—	2021	→
Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans.	Bigdeli TB et al.	—	2021	→
GRK3 deficiency elicits brain immune activation and psychosis.	Sellgren CM et al.	—	2021	→
Hidden Role of Gut Microbiome Dysbiosis in Schizophrenia: Antipsychotics or Psychobiotics as Therapeutics?	Munawar N et al.	—	2021	→
Hyperfocus: the forgotten frontier of attention.	Ashinoff BK et al.	—	2021	→
Identification of pleiotropy at the gene level between psychiatric disorders and related traits.	Polushina T et al.	—	2021	→
Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.	Peyrot WJ et al.	—	2021	→
<i>DRD1</i> and <i>DRD2</i> Receptor Polymorphisms: Genetic Neuromodulation of the Dopaminergic System as a Risk Factor for ASD, ADHD and ASD/ADHD Overlap.	Mariggiò MA et al.	—	2021	→
Imbalance between dopamine and serotonin caused by neonatal habenula lesion.	Lee YA et al.	—	2021	→
Individual Differences in Intertemporal Choice.	Keidel K et al.	—	2021	→
Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder.	Jia X et al.	—	2021	→
Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum.	Yang Z et al.	—	2021	→
Involvement of Rare Mutations of SCN9A, DPP4, ABCA13, and SYT14 in Schizophrenia and Bipolar Disorder.	Chen CH et al.	—	2021	→
Lower Hippocampal Volume in Patients with Schizophrenia and Bipolar Disorder: A Quantitative MRI Study.	Sato J et al.	—	2021	→
Machine learning for genetic prediction of psychiatric disorders: a systematic review.	Bracher-Smith M et al.	—	2021	→
Maintenance of Complex Trait Variation: Classic Theory and Modern Data.	Koch EM et al.	—	2021	→
Mapping Sex-Specific Neurodevelopmental Alterations in Neurite Density and Morphology in a Rat Genetic Model of Psychiatric Illness.	Barnett BR et al.	—	2021	→
Massively Parallel Reporter Assays: Defining Functional Psychiatric Genetic Variants Across Biological Contexts.	Mulvey B et al.	—	2021	→
Maternal acute and chronic inflammation in pregnancy is associated with common neurodevelopmental disorders: a systematic review.	Han VX et al.	—	2021	→
Maternal and paternal mental health problems and the risk of offspring depression in late adolescence: findings from the Raine study.	Ayano G et al.	—	2021	→
Maternal Distress and Offspring Neurodevelopment: Challenges and Opportunities for Pre-clinical Research Models.	Fitzgerald E et al.	—	2021	→
Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility.	Bruxel EM et al.	—	2021	→
Microglia Diversity in Healthy and Diseased Brain: Insights from Single-Cell Omics.	Ochocka N et al.	—	2021	→
Misdiagnosis, detection rate, and associated factors of severe psychiatric disorders in specialized psychiatry centers in Ethiopia.	Ayano G et al.	—	2021	→
Motivating and Discouraging Factors for Bipolar Patient Participation in Genomic Research.	Vallender EJ et al.	—	2021	→
Mutations in DISC1 alter IP<sub>3</sub>R and voltage-gated Ca<sup>2+</sup> channel functioning, implications for major mental illness.	Rittenhouse AR et al.	—	2021	→
Neuropsychiatric disorders: An immunological perspective.	Aw E et al.	—	2021	→
No evidence of associations between genetic liability for schizophrenia and development of cannabis use disorder.	Hjorthøj C et al.	—	2021	→
Parvalbumin interneuron vulnerability and brain disorders.	Ruden JB et al.	—	2021	→
Perturbations in Gut Microbiota Composition in Psychiatric Disorders: A Review and Meta-analysis.	Nikolova VL et al.	—	2021	→
Philipp Jolly and his 1913 "the heredity of psychosis": Homogeneity versus heterogeneity of familial transmission and an early look at Mendelian models for manic-depressive illness and dementia praecox.	Kendler KS et al.	—	2021	→
Pleiotropy between language impairment and broader behavioral disorders-an investigation of both common and rare genetic variants.	Nudel R et al.	—	2021	→
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms.	Rødevand L et al.	—	2021	→
Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals.	Kember RL et al.	—	2021	→
Polygenic risk score as clinical utility in psychiatry: a clinical viewpoint.	Ikeda M et al.	—	2021	→
Polygenic Score for Smoking is associated with Externalizing Psychopathology and Disinhibited Personality Traits but not Internalizing Psychopathology in Adolescence.	Hicks BM et al.	—	2021	→
Polymorphisms in the FKBP5 gene are associated with attention deficit and hyperactivity disorder in Korean children.	Kim HJ et al.	—	2021	→
Rates of contributory de novo mutation in high and low-risk autism families.	Yoon S et al.	—	2021	→
Repeated episodes of transient reduction of oxygen exposure simulating aircraft cabin conditions enhance resilience to stress in mice.	Ginerete RP et al.	—	2021	→
Risk in Relatives, Heritability, SNP-Based Heritability, and Genetic Correlations in Psychiatric Disorders: A Review.	Baselmans BML et al.	—	2021	→
Risk of conduct and oppositional defiant disorder symptoms in offspring of parents with mental health problems: Findings from the Raine Study.	Ayano G et al.	—	2021	→
Role of Ash1l in Tourette syndrome and other neurodevelopmental disorders.	Zhang C et al.	—	2021	→
Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning.	Crouse JJ et al.	—	2021	→
Self-reported medication use as an alternate phenotyping method for anxiety and depression in the UK Biobank.	Skelton M et al.	—	2021	→
SERINC2 increases the risk of bipolar disorder in the Chinese population.	Yang D et al.	—	2021	→
Sex specific effect of gut microbiota on the risk of psychiatric disorders: A Mendelian randomisation study and PRS analysis using UK Biobank cohort.	Qi X et al.	—	2021	→
Shared and distinct brain fMRI response during performance of working memory tasks in adult patients with schizophrenia and major depressive disorder.	Wang X et al.	—	2021	→
Sleep and Memory Consolidation Dysfunction in Psychiatric Disorders: Evidence for the Involvement of Extracellular Matrix Molecules.	Gisabella B et al.	—	2021	→
SNX29, a new susceptibility gene shared with major mental disorders in Han Chinese population.	Chen JH et al.	—	2021	→
Sphingolipid and Endocannabinoid Profiles in Adult Attention Deficit Hyperactivity Disorder.	Brunkhorst-Kanaan N et al.	—	2021	→
Structural brain imaging studies offer clues about the effects of the shared genetic etiology among neuropsychiatric disorders.	Radonjić NV et al.	—	2021	→
Subjective response to alcohol: Associated alcohol use and orbitofrontal gray matter volume in bipolar disorder.	Tretyak V et al.	—	2021	→
Targeting synaptic plasticity in schizophrenia: insights from genomic studies.	Mould AW et al.	—	2021	→
The Auditory Steady-State Response: Electrophysiological Index for Sensory Processing Dysfunction in Psychiatric Disorders.	Sugiyama S et al.	—	2021	→
The clinical characterization of the patient with primary psychosis aimed at personalization of management.	Maj M et al.	—	2021	→
The conserved ASTN2/BRINP1 locus at 9q33.1-33.2 is associated with major psychiatric disorders in a large pedigree from Southern Spain.	Pol-Fuster J et al.	—	2021	→
The epidemiology of psychiatric disorders in Africa: a scoping review.	Greene MC et al.	—	2021	→
The patterns of family genetic risk scores for eleven major psychiatric and substance use disorders in a Swedish national sample.	Kendler KS et al.	—	2021	→
The Polygenic Nature and Complex Genetic Architecture of Specific Learning Disorder.	Georgitsi M et al.	—	2021	→
The role of childhood trauma, HPA axis reactivity and FKBP5 genotype on cognition in healthy individuals.	Ferrer A et al.	—	2021	→
The Role of Ion Channel-Related Genes in Autism Spectrum Disorder: A Study Using Next-Generation Sequencing.	Lee J et al.	—	2021	→
The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder.	Faraone SV et al.	—	2021	→
Three decades of ASD genetics: building a foundation for neurobiological understanding and treatment.	Eyring KW et al.	—	2021	→
Three-Dimensional Convolutional Autoencoder Extracts Features of Structural Brain Images With a "Diagnostic Label-Free" Approach: Application to Schizophrenia Datasets.	Yamaguchi H et al.	—	2021	→
Transdiagnostic neuroimaging of reward system phenotypes in ADHD and comorbid disorders.	Grimm O et al.	—	2021	→
Transdiagnostic time-varying dysconnectivity across major psychiatric disorders.	Li C et al.	—	2021	→
Understanding the impact of SNPs associated with autism spectrum disorder on biological pathways in the human fetal and adult cortex.	Golovina E et al.	—	2021	→
Unveiling the Pathogenesis of Psychiatric Disorders Using Network Models.	Zuo Y et al.	—	2021	→
Urbanization and emerging mental health issues.	Ventriglio A et al.	—	2021	→
Using an adoption design to test genetically based differences in risk for child behavior problems in response to home environmental influences.	Cree RA et al.	—	2021	→
Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families.	Cao X et al.	—	2021	→
A Bibliometric Insight of Genetic Factors in ASD: Emerging Trends and New Developments.	Wang K et al.	—	2020	→
A Comprehensive Analysis of the Effect of SIRT1 Variation on the Risk of Schizophrenia and Depressive Symptoms.	Wang D et al.	—	2020	→
Adolescent cannabinoid exposure interacts with other risk factors in schizophrenia: A review of the evidence from animal models.	Dunn AL et al.	—	2020	→
Adult Neural Stem Cells as Promising Targets in Psychiatric Disorders.	Rodrigues RS et al.	—	2020	→
Affective lability in offspring of parents with major depressive disorder, bipolar disorder and schizophrenia.	Zwicker A et al.	—	2020	→
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine.	Guo Y et al.	—	2020	→
A genome-wide multiphenotypic association analysis identified candidate genes and gene ontology shared by four common risky behaviors.	Ye J et al.	—	2020	→
A joint study of whole exome sequencing and structural MRI analysis in major depressive disorder.	Zhang Y et al.	—	2020	→
Alterations in Task-Related Brain Activation in Children, Adolescents and Young Adults at Familial High-Risk for Schizophrenia or Bipolar Disorder - A Systematic Review.	Johnsen LK et al.	—	2020	→
Alterations of Cognition and Cerebral Ventricle Volume in Manic and Euthymic Pediatric Bipolar Disorder.	Kuang L et al.	—	2020	→
Altered peripheral blood compounds in drug-naïve first-episode patients with either schizophrenia or major depressive disorder: a meta-analysis.	Çakici N et al.	—	2020	→
A molecular approach to treating cognition in schizophrenia by calcium channel blockade: An open-label pilot study of the calcium-channel antagonist isradipine.	Burdick KE et al.	—	2020	→
An Extended Swedish National Adoption Study of Bipolar Disorder Illness and Cross-Generational Familial Association With Schizophrenia and Major Depression.	Kendler KS et al.	—	2020	→
An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study.	Dwyer DB et al.	—	2020	→
A Review of Antidepressant-Associated Hypomania in Those Diagnosed with Unipolar Depression-Risk Factors, Conceptual Models, and Management.	Gill N et al.	—	2020	→
A selective inference approach for false discovery rate control using multiomics covariates yields insights into disease risk.	Yurko R et al.	—	2020	→
Association Analysis Between Common Variants of the <i>TRPM1</i> Gene and Three Mental Disorders in the Han Chinese Population.	Ma C et al.	—	2020	→
Association Between Prematurity and Diagnosis of Neurodevelopment Disorder: A Case-Control Study.	Soncini TCB et al.	—	2020	→
Association of parental depression with offspring attention deficit hyperactivity disorder and autism spectrum disorder: A nationwide birth cohort study.	Chen LC et al.	—	2020	→
A transnosographic approach of negative symptoms pathophysiology in schizophrenia and depressive disorders.	Guessoum SB et al.	—	2020	→
Attention Deficit/Hyperactivity Disorder and risk for non-affective psychotic disorder: The role of ADHD medication and comorbidity, and sibling comparison.	Björkenstam E et al.	—	2020	→
Autism, Psychosis, or Both? Unraveling Complex Patient Presentations.	Chandrasekhar T et al.	—	2020	→
Autism spectrum disorder.	Lord C et al.	—	2020	→
Autism spectrum disorder genomics: The progress and potential of genomic technologies.	Ní Ghrálaigh F et al.	—	2020	→
Autistic spectrum disorder symptoms in children and adolescents with attention-deficit/hyperactivity disorder: a meta-analytical review.	Hollingdale J et al.	—	2020	→
Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.	Amare AT et al.	—	2020	→
Brain structural correlates of familial risk for mental illness: a meta-analysis of voxel-based morphometry studies in relatives of patients with psychotic or mood disorders.	Zhang W et al.	—	2020	→
Clock gene polygenic risk score and seasonality in major depressive disorder and bipolar disorder.	Ferrer A et al.	—	2020	→
Cohort profile: the Australian genetics of depression study.	Byrne EM et al.	—	2020	→
Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism.	Matoba N et al.	—	2020	→
Common variants in FAN1, located in 15q13.3, confer risk for schizophrenia and bipolar disorder in Han Chinese.	Jian X et al.	—	2020	→
Contribution of common and rare damaging variants in familial forms of bipolar disorder and phenotypic outcome.	Courtois E et al.	—	2020	→
Convergent brain microstructure across multiple genetic models of schizophrenia and autism spectrum disorder: A feasibility study.	Barnett BR et al.	—	2020	→
Copy number variants in siblings of Mexican origin concordant for schizophrenia or bipolar disorder.	Vega-Sevey JG et al.	—	2020	→
CORE GREML for estimating covariance between random effects in linear mixed models for complex trait analyses.	Zhou X et al.	—	2020	→
CRISPR-based functional evaluation of schizophrenia risk variants.	Rajarajan P et al.	—	2020	→
Cross-Disorder Analysis of Brain Structural Abnormalities in Six Major Psychiatric Disorders: A Secondary Analysis of Mega- and Meta-analytical Findings From the ENIGMA Consortium.	Opel N et al.	—	2020	→
C<sub>2</sub>H<sub>2</sub>-Type Zinc Finger Proteins in Brain Development, Neurodevelopmental, and Other Neuropsychiatric Disorders: Systematic Literature-Based Analysis.	Al-Naama N et al.	—	2020	→
Current challenges and possible future developments in personalized psychiatry with an emphasis on psychotic disorders.	Levchenko A et al.	—	2020	→
Demographics and Hospital Outcomes in American Women With Endometriosis and Psychiatric Comorbidities.	Robert CA et al.	—	2020	→
Discovery of shared genomic loci using the conditional false discovery rate approach.	Smeland OB et al.	—	2020	→
Distinguishing patterns of impairment on inhibitory control and general cognitive ability among bipolar with and without psychosis, schizophrenia, and schizoaffective disorder.	Gotra MY et al.	—	2020	→
Do Current Measures of Polygenic Risk for Mental Disorders Contribute to Population Variance in Mental Health?	Marsman A et al.	—	2020	→
Does SNORD116 mediate aspects of psychosis in Prader-Willi syndrome? Evidence from a non-clinical population.	Salminen I et al.	—	2020	→
Epigenome-wide association study of seizures in childhood and adolescence.	Caramaschi D et al.	—	2020	→
Evaluating the Impact of Nonrandom Mating: Psychiatric Outcomes Among the Offspring of Pairs Diagnosed With Schizophrenia and Bipolar Disorder.	Nordsletten AE et al.	—	2020	→
Exploring the neuropsychiatric spectrum using high-content functional analysis of single-cell signaling networks.	Lago SG et al.	—	2020	→
Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts.	Bond TA et al.	—	2020	→
Focus on Causality in ESC/iPSC-Based Modeling of Psychiatric Disorders.	Hoffmann A et al.	—	2020	→
From man to fly - convergent evidence links FBXO25 to ADHD and comorbid psychiatric phenotypes.	Harich B et al.	—	2020	→
Gene co-expression networks in peripheral blood capture dimensional measures of emotional and behavioral problems from the Child Behavior Checklist (CBCL).	Hess JL et al.	—	2020	→
Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia.	Evgrafov OV et al.	—	2020	→
Generalizable brain network markers of major depressive disorder across multiple imaging sites.	Yamashita A et al.	—	2020	→
Genetic Contributions to Multivariate Data-Driven Brain Networks Constructed via Source-Based Morphometry.	Rodrigue AL et al.	—	2020	→
Genetic cross-disorder analysis in psychiatry: from methodology to clinical utility.	Schijven D et al.	—	2020	→
Genetic feedback for psychiatric conditions: Where are we now and where are we going.	Driver MN et al.	—	2020	→
Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9.	Thorp JG et al.	—	2020	→
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.	Bryois J et al.	—	2020	→
Genetic Risk Assessment in Psychiatry.	Peay HL	—	2020	→
Genetics of ADHD: What Should the Clinician Know?	Grimm O et al.	—	2020	→
Genomic analysis of the natural history of attention-deficit/hyperactivity disorder using Neanderthal and ancient Homo sapiens samples.	Esteller-Cucala P et al.	—	2020	→
Guidance for identification and treatment of individuals with attention deficit/hyperactivity disorder and autism spectrum disorder based upon expert consensus.	Young S et al.	—	2020	→
GWAS SNPs Impact Shared Regulatory Pathways Amongst Multimorbid Psychiatric Disorders and Cognitive Functioning.	Golovina E et al.	—	2020	→
Homocysteine, but not MTHFR gene polymorphism, influences depressive symptoms in patients with schizophrenia.	Zhang Y et al.	—	2020	→
Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.	Cortes A et al.	—	2020	→
Identifying psychiatric disorder-associated gut microbiota using microbiota-related gene set enrichment analysis.	Cheng S et al.	—	2020	→
Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia.	Halvorsen M et al.	—	2020	→
Integrative genomics analysis of various omics data and networks identify risk genes and variants vulnerable to childhood-onset asthma.	Ma X et al.	—	2020	→
Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer's disease.	Morabito S et al.	—	2020	→
Language deficits in specific language impairment, attention deficit/hyperactivity disorder, and autism spectrum disorder: An analysis of polygenic risk.	Nudel R et al.	—	2020	→
Leveraging correlations between variants in polygenic risk scores to detect heterogeneity in GWAS cohorts.	Yuan J et al.	—	2020	→
Look duration at the face as a developmental endophenotype: elucidating pathways to autism and ADHD.	Gui A et al.	—	2020	→
Lowering costs for large-scale screening in psychosis: a systematic review and meta-analysis of performance and value of information for speech-based psychiatric evaluation.	Argolo F et al.	—	2020	→
LPM: a latent probit model to characterize the relationship among complex traits using summary statistics from multiple GWASs and functional annotations.	Ming J et al.	—	2020	→
Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness.	Ching CRK et al.	—	2020	→
Mental health is biological health: Why tackling "diseases of the mind" is an imperative for biological anthropology in the 21st century.	Syme KL et al.	—	2020	→
Metabolic Changes in Synaptosomes in an Animal Model of Schizophrenia Revealed by <sup>1</sup>H and <sup>1</sup>H,<sup>13</sup>C NMR Spectroscopy.	Barnett BR et al.	—	2020	→
Modeling Psychiatric Disorder Biology with Stem Cells.	Das D et al.	—	2020	→
Molecular genetics in psychology and personality neuroscience: On candidate genes, genome wide scans, and new research strategies.	Montag C et al.	—	2020	→
mTADA is a framework for identifying risk genes from de novo mutations in multiple traits.	Nguyen TH et al.	—	2020	→
Multi-trait analysis for genome-wide association study of five psychiatric disorders.	Wu Y et al.	—	2020	→
Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia.	Moreau CA et al.	—	2020	→
Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings.	Scaini G et al.	—	2020	→
Neurodevelopmental concepts of schizophrenia in the genome-wide association era: AKT/mTOR signaling as a pathological mediator of genetic and environmental programming during development.	Howell KR et al.	—	2020	→
Neuropsychiatric "Comorbidity" as Causal Influence in Autism.	Hawks ZW et al.	—	2020	→
Nordic OCD & Related Disorders Consortium: Rationale, design, and methods.	Mataix-Cols D et al.	—	2020	→
Olfactory Dysfunction in Neurodevelopmental Disorders: A Meta-analytic Review of Autism Spectrum Disorders, Attention Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder.	Crow AJD et al.	—	2020	→
On the diagnostic and neurobiological origins of bipolar disorder.	Charney AW et al.	—	2020	→
Pairwise common variant meta-analyses of schizophrenia with other psychiatric disorders reveals shared and distinct gene and gene-set associations.	Reay WR et al.	—	2020	→
Partitioning heritability analyses unveil the genetic architecture of human brain multidimensional functional connectivity patterns.	Feng J et al.	—	2020	→
Polygenic prediction of the risk of perinatal depressive symptoms.	Rantalainen V et al.	—	2020	→
Polygenic risk and pleiotropy in neurodegenerative diseases.	Bellou E et al.	—	2020	→
Polygenic risk for autism spectrum disorder affects left amygdala activity and negative emotion in schizophrenia.	Qin Y et al.	—	2020	→
Polygenic Risk Scores for Developmental Disorders, Neuromotor Functioning During Infancy, and Autistic Traits in Childhood.	Serdarevic F et al.	—	2020	→
Psychiatric comorbidity among women with endometriosis: nationwide cohort study in Sweden.	Gao M et al.	—	2020	→
Psychiatric Disorders and lncRNAs: A Synaptic Match.	Rusconi F et al.	—	2020	→
Psychiatric Polygenic Risk Scores as Predictor for Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in a Clinical Child and Adolescent Sample.	Jansen AG et al.	—	2020	→
Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study.	Nudel R et al.	—	2020	→
Rare single-nucleotide DAB1 variants and their contribution to Schizophrenia and autism spectrum disorder susceptibility.	Nawa Y et al.	—	2020	→
Redefining phenotypes to advance psychiatric genetics: Implications from hierarchical taxonomy of psychopathology.	Waszczuk MA et al.	—	2020	→
Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice.	Rajkumar AP et al.	—	2020	→
Risk Stratification for Bipolar Disorder Using Polygenic Risk Scores Among Young High-Risk Adults.	Biere S et al.	—	2020	→
Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study.	Bahrami S et al.	—	2020	→
Similar impairments shown on a neuropsychological test battery in adolescents with high-functioning autism and early onset schizophrenia: a two-year follow-up study.	Øie MG et al.	—	2020	→
Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures.	Harris MA et al.	—	2020	→
Structural brain morphometry associated with theory of mind in bipolar disorder and schizophrenia.	Quidé Y et al.	—	2020	→
Synaptic and brain-expressed gene sets relate to the shared genetic risk across five psychiatric disorders.	Hammerschlag AR et al.	—	2020	→
Targeted sequencing of the BDNF gene in young Chinese Han people with major depressive disorder.	Zhang C et al.	—	2020	→
Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism.	Chao OY et al.	—	2020	→
The Core Deficit of “Classical” Schizophrenia Cuts Across the Psychosis Spectrum.	Keshavan MS et al.	—	2020	→
The Heterogeneity of Mental Health Assessment.	Newson JJ et al.	—	2020	→
The impact on estimations of genetic correlations by the use of super-normal, unscreened, and family-history screened controls in genome wide case-control studies.	Kendler KS et al.	—	2020	→
The importance of a developmental perspective in Psychiatry: what do recent genetic-epidemiological findings show?	Thapar A et al.	—	2020	→
The persistence of child and adolescence mental healthcare: results from registry data.	Dijk HH et al.	—	2020	→
The State of Our Understanding of the Pathophysiology and Optimal Treatment of Depression: Glass Half Full or Half Empty?	Nemeroff CB	—	2020	→
Top ten discoveries of the year: Neurodevelopmental disorders.	Dierssen M	—	2020	→
Transdiagnostic Dysfunctions in Brain Modules Across Patients with Schizophrenia, Bipolar Disorder, and Major Depressive Disorder: A Connectome-Based Study.	Ma Q et al.	—	2020	→
Transdiagnostic neurocognitive subgroups and functional course in young people with emerging mental disorders: a cohort study.	Crouse JJ et al.	—	2020	→
Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect.	Krebs CE et al.	—	2020	→
Whole-Genome Approach Discovers Novel Genetic and Nongenetic Variance Components Modulated by Lifestyle for Cardiovascular Health.	Zhou X et al.	—	2020	→
Will machine learning applied to neuroimaging in bipolar disorder help the clinician? A critical review and methodological suggestions.	Claude LA et al.	—	2020	→
A 12-month prospective study on the time to hospitalization and clinical management of a cohort of bipolar type I and schizoaffective bipolar patients.	Murru A et al.	—	2019	→
A choose your own adventure story: Conceptualizing depression in children and adolescents from traditional DSM and alternative latent dimensional approaches.	Hankin BL	—	2019	→
A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment.	Schork AJ et al.	—	2019	→
A kainate receptor GluK4 deletion, protective against bipolar disorder, is associated with enhanced cognitive performance across diagnoses in the TwinsUK cohort.	Koromina M et al.	—	2019	→
A model of human endogenous retrovirus (HERV) activation in mental health and illness.	Canli T	—	2019	→
Annual Research Review: Maternal antidepressant use during pregnancy and offspring neurodevelopmental problems - a critical review and recommendations for future research.	Sujan AC et al.	—	2019	→
A population-based heritability estimate of bipolar disorder - In a Swedish twin sample.	Johansson V et al.	—	2019	→
A quantitative approach to neuropsychiatry: The why and the how.	Kas MJ et al.	—	2019	→
A risk calculator to predict adult attention-deficit/hyperactivity disorder: generation and external validation in three birth cohorts and one clinical sample.	Caye A et al.	—	2019	→
Association Between Childhood Anhedonia and Alterations in Large-scale Resting-State Networks and Task-Evoked Activation.	Pornpattananangkul N et al.	—	2019	→
Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population.	Musliner KL et al.	—	2019	→
Attention-deficit/hyperactivity disorder and clinically diagnosed obesity in adolescence and young adulthood: a register-based study in Sweden.	Chen Q et al.	—	2019	→
Attention-deficit/hyperactivity disorder and risk for psychiatric and neurodevelopmental disorders in siblings.	Jokiranta-Olkoniemi E et al.	—	2019	→
Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions.	Ristori MV et al.	—	2019	→
Basic symptoms in offspring of parents with mood and psychotic disorders.	Zwicker A et al.	—	2019	→
Behavior and Molecular Genetic Approaches to Comorbidity.	Willcutt EG	—	2019	→
Biomarker Research in ADHD: the Impact of Nutrition (BRAIN) - study protocol of an open-label trial to investigate the mechanisms underlying the effects of a few-foods diet on ADHD symptoms in children.	Stobernack T et al.	—	2019	→
[Breakthrough in understanding the molecular causes of psychiatric disorders].	Nöthen MM et al.	—	2019	→
Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia.	de Vrij FM et al.	—	2019	→
Characterizing Developmental Trajectories and the Role of Neuropsychiatric Genetic Risk Variants in Early-Onset Depression.	Rice F et al.	—	2019	→
Chromatin Remodeling Complex NuRD in Neurodevelopment and Neurodevelopmental Disorders.	Hoffmann A et al.	—	2019	→
CIBERSAM: Ten years of collaborative translational research in mental disorders.	Salagre E et al.	—	2019	→
Clinical phenotype and genetic risk factors for bipolar disorder with binge eating: an update.	Cuellar-Barboza AB et al.	—	2019	→
Closing the 'phenotype gap' in precision medicine: improving what we measure to understand complex disease mechanisms.	MacRae CA	—	2019	→
Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder.	Guan J et al.	—	2019	→
Common and Specific Functional Activity Features in Schizophrenia, Major Depressive Disorder, and Bipolar Disorder.	Yang Y et al.	—	2019	→
Common Dysfunction of Large-Scale Neurocognitive Networks Across Psychiatric Disorders.	Sha Z et al.	—	2019	→
Comparative genetic architectures of schizophrenia in East Asian and European populations.	Lam M et al.	—	2019	→
Complex Trait Prediction from Genome Data: Contrasting EBV in Livestock to PRS in Humans: Genomic Prediction.	Wray NR et al.	—	2019	→
Computational Approaches for Identification of Pleiotropic Biomarker Profiles in Psychiatry.	Cao H et al.	—	2019	→
Continuity of genetic and environmental influences on clinically assessed major depression from ages 18 to 45.	Torvik FA et al.	—	2019	→
Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases.	Charney AW et al.	—	2019	→
Convolutional neural network model to predict causal risk factors that share complex regulatory features.	Lee T et al.	—	2019	→
Cortico-limbic connectivity as a possible biomarker for bipolar disorder: where are we now?	Vai B et al.	—	2019	→
Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk.	Pouget JG et al.	—	2019	→
Cytochrome P450 2C19 Poor Metabolizer Phenotype in Treatment Resistant Depression: Treatment and Diagnostic Implications.	Veldic M et al.	—	2019	→
Damaging coding variants within kainate receptor channel genes are enriched in individuals with schizophrenia, autism and intellectual disabilities.	Koromina M et al.	—	2019	→
Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders.	Sullivan PF et al.	—	2019	→
Depression genetic risk score is associated with anhedonia-related markers across units of analysis.	Guffanti G et al.	—	2019	→
Diagnostic Issues of Depressive Disorders from Kraepelinian Dualism to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.	Park SC et al.	—	2019	→
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.	Demontis D et al.	—	2019	→
Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language.	Verhoef E et al.	—	2019	→
Disrupted-in-schizophrenia 1 functional polymorphisms and D<sub>2</sub> /D<sub>3</sub> receptor availability: A [<sup>11</sup> C]-(+)-PHNO imaging study.	Dahoun T et al.	—	2019	→
DNA methylation signatures as biomarkers of prior environmental exposures.	Ladd-Acosta C et al.	—	2019	→
Drug discovery for psychiatric disorders using high-content single-cell screening of signaling network responses ex vivo.	Lago SG et al.	—	2019	→
Effect of disease-associated SLC9A9 mutations on protein-protein interaction networks: implications for molecular mechanisms for ADHD and autism.	Zhang-James Y et al.	—	2019	→
Effort valuation and psychopathology in children and adults.	Nguyen NH et al.	—	2019	→
Electroconvulsive shock restores the decreased coverage of brain blood vessels by astrocytic endfeet and ameliorates depressive-like behavior.	Azis IA et al.	—	2019	→
eQTLs Weighted Genetic Correlation Analysis Detected Brain Region Differences in Genetic Correlations for Complex Psychiatric Disorders.	Wen Y et al.	—	2019	→
Estimating cross-population genetic correlations of causal effect sizes.	Galinsky KJ et al.	—	2019	→
Estimating variance components in population scale family trees.	Shor T et al.	—	2019	→
Evidence for interaction between genetic liability and childhood trauma in the development of psychotic symptoms.	Pinckaers FME et al.	—	2019	→
Exome sequencing in families with severe mental illness identifies novel and rare variants in genes implicated in Mendelian neuropsychiatric syndromes.	Ganesh S et al.	—	2019	→
From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder.	Wolfers T et al.	—	2019	→
From the neo-Kraepelinian framework to the new mechanical philosophy of psychiatry: regaining common sense	Joober R et al.	—	2019	→
GAD1 gene polymorphisms are associated with bipolar I disorder and with blood homovanillic acid levels but not with plasma GABA levels.	Arrúe A et al.	—	2019	→
Gene-based analysis of ADHD using PASCAL: a biological insight into the novel associated genes.	Alonso-Gonzalez A et al.	—	2019	→
Genetic analysis for cognitive flexibility in the trail-making test in attention deficit hyperactivity disorder patients from single nucleotide polymorphism, gene to pathway level.	Zhang K et al.	—	2019	→
Genetic Causes and Modifiers of Autism Spectrum Disorder.	Rylaarsdam L et al.	—	2019	→
Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders.	Bauer AE et al.	—	2019	→
Genetics and genetic counseling in psychiatry: Results from an opinion survey of professionals and users.	Martorell L et al.	—	2019	→
Genetics of attention deficit hyperactivity disorder.	Faraone SV et al.	—	2019	→
Genetic Studies of Tic Disorders and Tourette Syndrome.	Qi Y et al.	—	2019	→
Genetic variability in the serotoninergic system and age of onset in anorexia nervosa and obsessive-compulsive disorder.	Plana MT et al.	—	2019	→
Genetic variants in major depressive disorder: From pathophysiology to therapy.	Gonda X et al.	—	2019	→
Genome-wide association meta-analysis of cocaine dependence: Shared genetics with comorbid conditions.	Cabana-Domínguez J et al.	—	2019	→
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.	Ikeda M et al.	—	2019	→
Genome-wide association study identifies 30 loci associated with bipolar disorder.	Stahl EA et al.	—	2019	→
Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts.	Zhang X et al.	—	2019	→
Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.	Arnau-Soler A et al.	—	2019	→
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.	Cross-Disorder Group of the Psychiatric Genomics Consortium. Electronic address: plee0@mgh.harvard.edu et al.	—	2019	→
Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits.	Grotzinger AD et al.	—	2019	→
Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model.	Ni G et al.	—	2019	→
Getting to the Cores of Autism.	Iakoucheva LM et al.	—	2019	→
GWAS of Behavioral Traits.	Mehta D et al.	—	2019	→
How genome-wide association studies (GWAS) made traditional candidate gene studies obsolete.	Duncan LE et al.	—	2019	→
Human brain arousal in the resting state: a genome-wide association study.	Jawinski P et al.	—	2019	→
<i>De novo</i> Mutations From Whole Exome Sequencing in Neurodevelopmental and Psychiatric Disorders: From Discovery to Application.	Wang W et al.	—	2019	→
Identification of common genetic risk variants for autism spectrum disorder.	Grove J et al.	—	2019	→
Identification of Common Thalamocortical Dysconnectivity in Four Major Psychiatric Disorders.	Tu PC et al.	—	2019	→
Identification of genes related to mental disorders by text mining.	Wu Y et al.	—	2019	→
Imaging Genetics Towards a Refined Diagnosis of Schizophrenia.	Jiang W et al.	—	2019	→
Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses.	Yuan N et al.	—	2019	→
Integrating Genomics into Psychiatric Practice: Ethical and Legal Challenges for Clinicians.	Ward ET et al.	—	2019	→
Interaction between environmental and familial affective risk impacts psychosis admixture in states of affective dysregulation.	Radhakrishnan R et al.	—	2019	→
Interaction of schizophrenia polygenic risk and cortisol level on pre-adolescent brain structure.	Bolhuis K et al.	—	2019	→
Longitudinal trajectory of early functional recovery in patients with first episode psychosis.	Hall MH et al.	—	2019	→
Loss of Cntnap2 Causes Axonal Excitability Deficits, Developmental Delay in Cortical Myelination, and Abnormal Stereotyped Motor Behavior.	Scott R et al.	—	2019	→
MeCP2 Dysfunction in Rett Syndrome and Neuropsychiatric Disorders.	Chin EWM et al.	—	2019	→
Metabolomics Biomarkers for Precision Psychiatry.	Shih PB	—	2019	→
Multivariate analysis of genome-wide data to identify potential pleiotropic genes for five major psychiatric disorders using MetaCCA.	Jia X et al.	—	2019	→
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Optimal Estimation of Genetic Relatedness in High-dimensional Linear Models.	Guo Z et al.	—	2019	→
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Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder.	Lanz TA et al.	—	2019	→
Powerful and Efficient Strategies for Genetic Association Testing of Symptom and Questionnaire Data in Psychiatric Genetic Studies.	Holleman AM et al.	—	2019	→
Predicting rehospitalization within 2 years of initial patient admission for a major depressive episode: a multimodal machine learning approach.	Cearns M et al.	—	2019	→
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Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder.	Trzaskowski M et al.	—	2019	→
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Relationships between substance abuse/dependence and psychiatric disorders based on polygenic scores.	Gurriarán X et al.	—	2019	→
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Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder.	Schwarz E et al.	—	2019	→
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Risk and coaggregation of major psychiatric disorders among first-degree relatives of patients with bipolar disorder: a nationwide population-based study.	Chen MH et al.	—	2019	→
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Serotonergic multilocus genetic variation moderates the association between major interpersonal stress and adolescent depressive symptoms: Replication and candidate environment specification.	Starr LR et al.	—	2019	→
Sex-specific deficits in neurite density and white matter integrity are associated with targeted disruption of exon 2 of the Disc1 gene in the rat.	Barnett BR et al.	—	2019	→
Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap.	Gandal MJ et al.	—	2019	→
Shared preventive factors associated with relapse after a response to electroconvulsive therapy in four major psychiatric disorders.	Omori W et al.	—	2019	→
Sibling Recurrence Risk and Cross-aggregation of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder.	Miller M et al.	—	2019	→
Slower and Less Variable Binocular Rivalry Rates in Patients With Bipolar Disorder, OCD, Major Depression, and Schizophrenia.	Ye X et al.	—	2019	→
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The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder.	de Zwarte SMC et al.	—	2019	→
The Association Between Schizophrenia Risk Variants and Creativity in Healthy Han Chinese Subjects.	Wang D et al.	—	2019	→
The Emerging Neurobiology of Bipolar Disorder.	Harrison PJ et al.	—	2019	→
The emerging pattern of shared polygenic architecture of psychiatric disorders, conceptual and methodological challenges.	Smeland OB et al.	—	2019	→
The Functional Brain Organization of an Individual Allows Prediction of Measures of Social Abilities Transdiagnostically in Autism and Attention-Deficit/Hyperactivity Disorder.	Lake EMR et al.	—	2019	→
The genetic and environmental etiology of child maltreatment in a parent-based extended family design.	Pittner K et al.	—	2019	→
The genetics of neuropsychiatric disorders.	Bray NJ et al.	—	2019	→
The genomics of major psychiatric disorders in a large pedigree from Northern Sweden.	Szatkiewicz J et al.	—	2019	→
The Role of <i>MIR9-2</i> in Shared Susceptibility of Psychiatric Disorders during Childhood: A Population-Based Birth Cohort Study.	Tovo-Rodrigues L et al.	—	2019	→
The Translational Potential of Neuroimaging Genomic Analyses To Diagnosis And Treatment In The Mental Disorders.	Chen J et al.	—	2019	→
Three Novel Players: PTK2B, SYK, and TNFRSF21 Were Identified to Be Involved in the Regulation of Bovine Mastitis Susceptibility via GWAS and Post-transcriptional Analysis.	Yang F et al.	—	2019	→
Toward a Better Understanding of Neuronal Migration Deficits in Autism Spectrum Disorders.	Pan YH et al.	—	2019	→
Towards a new model of understanding - The triple network, psychopathology and the structure of the mind.	Menon B	—	2019	→
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Translating GWAS findings into therapies for depression and anxiety disorders: gene-set analyses reveal enrichment of psychiatric drug classes and implications for drug repositioning.	So HC et al.	—	2019	→
Translational bioinformatics in mental health: open access data sources and computational biomarker discovery.	Tenenbaum JD et al.	—	2019	→
Truncating variant burden in high-functioning autism and pleiotropic effects of LRP1 across psychiatric phenotypes	Torrico B et al.	—	2019	→
Unravelling the genetic basis of schizophrenia and bipolar disorder with GWAS: A systematic review.	Prata DP et al.	—	2019	→
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A Connectome-wide Functional Signature of Transdiagnostic Risk for Mental Illness.	Elliott ML et al.	—	2018	→
A data-driven investigation of relationships between bipolar psychotic symptoms and schizophrenia genome-wide significant genetic loci.	Leonenko G et al.	—	2018	→
Adverse life events, psychiatric history, and biological predictors of postpartum depression in an ethnically diverse sample of postpartum women.	Guintivano J et al.	—	2018	→
A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder.	Martin J et al.	—	2018	→
Analysis of Gene Expression Variance in Schizophrenia Using Structural Equation Modeling.	Igolkina AA et al.	—	2018	→
Analysis of shared heritability in common disorders of the brain.	Brainstorm Consortium et al.	—	2018	→
An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations.	Majumdar A et al.	—	2018	→
An examination of multiple classes of rare variants in extended families with bipolar disorder.	Toma C et al.	—	2018	→
Another Round of "Clue" to Uncover the Mystery of Complex Traits.	Verma SS et al.	—	2018	→
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A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains.	Ranlund S et al.	—	2018	→
A population genetic interpretation of GWAS findings for human quantitative traits.	Simons YB et al.	—	2018	→
A Potential Role for the Noncoding Transcriptome in Psychiatric Disorders.	Klengel T	—	2018	→
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.	de Jong S et al.	—	2018	→
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Assessment of a glyoxalase I frameshift variant, p.P122fs, in Japanese patients with schizophrenia.	Ishizuka K et al.	—	2018	→
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Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.	Evans LM et al.	—	2018	→
Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.	Yang CP et al.	—	2018	→
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Copy Number Variation Analysis of 100 Twin Pairs Enriched for Neurodevelopmental Disorders.	Stamouli S et al.	—	2018	→
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Deconstructing and targeting the genomic architecture of human neurodegeneration.	De Jager PL et al.	—	2018	→
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Differentiating positive schizotypy and mania risk scales and their associations with spontaneous eye blink rate.	Hua JPY et al.	—	2018	→
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DNA methylation analyses of the candidate genes identified by a methylome-wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder.	Sugawara H et al.	—	2018	→
Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.	Peyrot WJ et al.	—	2018	→
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Embracing polygenicity: a review of methods and tools for psychiatric genetics research.	Maier RM et al.	—	2018	→
Empirical Bayes Estimation of Semi-parametric Hierarchical Mixture Models for Unbiased Characterization of Polygenic Disease Architectures.	Nishino J et al.	—	2018	→
Enhancing Psychosis-Spectrum Nosology Through an International Data Sharing Initiative.	Docherty AR et al.	—	2018	→
Epigenetics applied to psychiatry: Clinical opportunities and future challenges.	Kular L et al.	—	2018	→
Epigenetics, maternal prenatal psychosocial stress, and infant mental health.	DeSocio JE	—	2018	→
Estimating SNP-Based Heritability and Genetic Correlation in Case-Control Studies Directly and with Summary Statistics.	Weissbrod O et al.	—	2018	→
Evidence That Environmental and Familial Risks for Psychosis Additively Impact a Multidimensional Subthreshold Psychosis Syndrome.	Pries LK et al.	—	2018	→
Examining cognition across the bipolar/schizophrenia diagnostic spectrum.	Lynham AJ et al.	—	2018	→
Exome sequencing in large, multiplex bipolar disorder families from Cuba.	Maaser A et al.	—	2018	→
Exploring the relationship between vitamin D and mania: correlations between serum vitamin D levels and disease activity.	Altunsoy N et al.	—	2018	→
Family History as an Important Factor for Stratifying Participants in Genetic Studies of Major Depression.	Zalar B et al.	—	2018	→
Fgf9 <sup>Y162C</sup> Mutation Alters Information Processing and Social Memory in Mice.	Garrett L et al.	—	2018	→
FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses.	Cattaneo A et al.	—	2018	→
Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication.	Vedal TSJ et al.	—	2018	→
From Maps to Multi-dimensional Network Mechanisms of Mental Disorders.	Braun U et al.	—	2018	→
From the Psychiatrist's Couch to Induced Pluripotent Stem Cells: Bipolar Disease in a Dish.	Hoffmann A et al.	—	2018	→
Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD.	Schäfer N et al.	—	2018	→
Functional Partitioning of Genomic Variance and Genome-Wide Association Study for Carcass Traits in Korean Hanwoo Cattle Using Imputed Sequence Level SNP Data.	Bhuiyan MSA et al.	—	2018	→
Functional TSPO polymorphism predicts variance in the diurnal cortisol rhythm in bipolar disorder.	Prossin AR et al.	—	2018	→
Gene-environment interaction and psychiatric disorders: Review and future directions.	Assary E et al.	—	2018	→
Gene-environment interplay in the etiology of psychosis.	Zwicker A et al.	—	2018	→
Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP).	Ren H et al.	—	2018	→
Genetic analysis of deep phenotyping projects in common disorders.	Gershon ES et al.	—	2018	→
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Genetic Correlation Profile of Schizophrenia Mirrors Epidemiological Results and Suggests Link Between Polygenic and Rare Variant (22q11.2) Cases of Schizophrenia.	Duncan LE et al.	—	2018	→
Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data.	Tylee DS et al.	—	2018	→
Genetic pleiotropy between mood disorders, metabolic, and endocrine traits in a multigenerational pedigree.	Kember RL et al.	—	2018	→
Genetic risk scores and family history as predictors of schizophrenia in Nordic registers.	Lu Y et al.	—	2018	→
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Genetics of co-developing conduct and emotional problems during childhood and adolescence.	Hannigan LJ et al.	—	2018	→
Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records.	Chen CY et al.	—	2018	→
Genetic variability in scaffolding proteins and risk for schizophrenia and autism-spectrum disorders: a systematic review.	Soler J et al.	—	2018	→
Genome-wide analysis of adolescent psychotic-like experiences shows genetic overlap with psychiatric disorders.	Pain O et al.	—	2018	→
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.	Wray NR et al.	—	2018	→
Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records.	McCoy TH et al.	—	2018	→
Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD.	Van der Auwera S et al.	—	2018	→
Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank.	Hall LS et al.	—	2018	→
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.	Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address: douglas.ruderfer@vanderbilt.edu et al.	—	2018	→
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.	Finucane HK et al.	—	2018	→
Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.	Qi G et al.	—	2018	→
Heritable Variation, With Little or No Maternal Effect, Accounts for Recurrence Risk to Autism Spectrum Disorder in Sweden.	Yip BHK et al.	—	2018	→
High-Dimensional Immunology for Schizophrenia Research: A Short Perspective.	Lewis GK	—	2018	→
High Throughput Phenotyping for Dimensional Psychopathology in Electronic Health Records.	McCoy TH et al.	—	2018	→
HLA genetics in bipolar disorder.	Tamouza R et al.	—	2018	→
Host genetics and microbiome associations through the lens of genome wide association studies.	Weissbrod O et al.	—	2018	→
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How Stress Gets Under the Skin: Early Life Adversity and Glucocorticoid Receptor Epigenetic Regulation.	Liu PZ et al.	—	2018	→
Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue.	Bhalala OG et al.	—	2018	→
Improved ethical guidance for the return of results from psychiatric genomics research.	Lázaro-Muñoz G et al.	—	2018	→
Improving genetic prediction by leveraging genetic correlations among human diseases and traits.	Maier RM et al.	—	2018	→
Improving SNP prioritization and pleiotropic architecture estimation by incorporating prior knowledge using graph-GPA.	Kim HJ et al.	—	2018	→
Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review.	Misiak B et al.	—	2018	→
Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways.	Nguyen RL et al.	—	2018	→
Investigating the genetic architecture of general and specific psychopathology in adolescence.	Jones HJ et al.	—	2018	→
Levels of Cognitive Control: A Functional Magnetic Resonance Imaging-Based Test of an RDoC Domain Across Bipolar Disorder and Schizophrenia.	Smucny J et al.	—	2018	→
Linked dimensions of psychopathology and connectivity in functional brain networks.	Xia CH et al.	—	2018	→
Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan.	Franke B et al.	—	2018	→
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Longitudinal association between mental disorders in childhood and subsequent depression - A nationwide prospective cohort study.	Gundel LK et al.	—	2018	→
Lost in Translation: Traversing the Complex Path from Genomics to Therapeutics in Autism Spectrum Disorder.	Sestan N et al.	—	2018	→
Mini-review: Update on the genetics of schizophrenia.	Coelewij L et al.	—	2018	→
Mitochondria, Microglia, and the Immune System-How Are They Linked in Affective Disorders?	Culmsee C et al.	—	2018	→
nArgBP2-SAPAP-SHANK, the core postsynaptic triad associated with psychiatric disorders.	Lee SE et al.	—	2018	→
Neuroanatomical phenotypes in mental illness: identifying convergent and divergent cortical phenotypes across autism, ADHD and schizophrenia.	Park MTM et al.	—	2018	→
Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes.	Herborg F et al.	—	2018	→
Nineteen and Up study (19Up): understanding pathways to mental health disorders in young Australian twins.	Couvy-Duchesne B et al.	—	2018	→
Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities.	Li H et al.	—	2018	→
Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment.	Shadrin AA et al.	—	2018	→
Opportunities for an enhanced integration of neuroscience and genomics.	Moore AA et al.	—	2018	→
P2X7 Receptor: A Potential Therapeutic Target for Depression?	Deussing JM et al.	—	2018	→
Partitioning the Pleiotropy Between Coronary Artery Disease and Body Mass Index Reveals the Importance of Low Frequency Variants and Central Nervous System-Specific Functional Elements.	Nikpay M et al.	—	2018	→
Paternal use of antidepressants and offspring outcomes in Sweden: nationwide prospective cohort study.	Viktorin A et al.	—	2018	→
Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment.	Yeh E et al.	—	2018	→
Pleiotropic mapping and annotation selection in genome-wide association studies with penalized Gaussian mixture models.	Zeng P et al.	—	2018	→
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Positron emission tomography assessment of cerebral glucose metabolic rates in autism spectrum disorder and schizophrenia.	Mitelman SA et al.	—	2018	→
Post-GWAS in Psychiatric Genetics: A Developmental Perspective on the "Other" Next Steps.	Dick DM et al.	—	2018	→
Predicting loneliness with polygenic scores of social, psychological and psychiatric traits.	Abdellaoui A et al.	—	2018	→
Prenatal mercury exposure and features of autism: a prospective population study.	Golding J et al.	—	2018	→
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Quantitative mapping of genetic similarity in human heritable diseases by shared mutations.	Zhao H et al.	—	2018	→
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Trauma exposure interacts with the genetic risk of bipolar disorder in alcohol misuse of US soldiers.	Polimanti R et al.	—	2018	→
Treatment resistant depression: A multi-scale, systems biology approach.	Akil H et al.	—	2018	→
Understanding the Molecular Mechanisms Underpinning Gene by Environment Interactions in Psychiatric Disorders: The FKBP5 Model.	Matosin N et al.	—	2018	→
Uneven Distribution of Mutational Variance Across the Transcriptome of <i>Drosophila serrata</i> Revealed by High-Dimensional Analysis of Gene Expression.	Hine E et al.	—	2018	→
Validation of a microRNA target site polymorphism in H3F3B that is potentially associated with a broad schizophrenia phenotype.	Manley W et al.	—	2018	→
Variability in Resting State Network and Functional Network Connectivity Associated With Schizophrenia Genetic Risk: A Pilot Study.	Chen J et al.	—	2018	→
What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics.	Nurnberger JI et al.	—	2018	→
A Multilevel Functional Study of a <i>SNAP25</i> At-Risk Variant for Bipolar Disorder and Schizophrenia.	Houenou J et al.	—	2017	→
A novel rare variant R292H in RTN4R affects growth cone formation and possibly contributes to schizophrenia susceptibility.	Kimura H et al.	—	2017	→
A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics.	Lu Q et al.	—	2017	→
Attention and motor deficits index non-specific background liabilities that predict autism recurrence in siblings.	Mous SE et al.	—	2017	→
Bio-collections in autism research.	Reilly J et al.	—	2017	→
Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations.	Prata J et al.	—	2017	→
Childhood adversities and clinical symptomatology in first-episode psychosis.	Lindgren M et al.	—	2017	→
Childhood behaviour problems show the greatest gap between DNA-based and twin heritability.	Cheesman R et al.	—	2017	→
Classification of common human diseases derived from shared genetic and environmental determinants.	Wang K et al.	—	2017	→
Concepts, estimation and interpretation of SNP-based heritability.	Yang J et al.	—	2017	→
Copy number variation meta-analysis reveals a novel duplication at 9p24 associated with multiple neurodevelopmental disorders.	Glessner JT et al.	—	2017	→
Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder.	Andrews SV et al.	—	2017	→
DeepBipolar: Identifying genomic mutations for bipolar disorder via deep learning.	Sundaram L et al.	—	2017	→
Efficient genome-wide association in biobanks using topic modeling identifies multiple novel disease loci.	McCoy TH et al.	—	2017	→
Epigenomics of Major Depressive Disorders and Schizophrenia: Early Life Decides.	Hoffmann A et al.	—	2017	→
Evaluation of the interaction between genetic variants of GAD1 and miRNA in bipolar disorders.	Chung YE et al.	—	2017	→
Evidence that eye-movement profiles do not explain slow binocular rivalry rate in bipolar disorder: support for a perceptual endophenotype.	Law PC et al.	—	2017	→
Familial Aggregation and Heritability of Schizophrenia and Co-aggregation of Psychiatric Illnesses in Affected Families.	Chou IJ et al.	—	2017	→
Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses.	Pandey H et al.	—	2017	→
Genetic Overlap Between Schizophrenia and Developmental Psychopathology: Longitudinal and Multivariate Polygenic Risk Prediction of Common Psychiatric Traits During Development.	Nivard MG et al.	—	2017	→
Genetics of Depression: Progress at Last.	Mullins N et al.	—	2017	→
Genetics of depressive symptoms in adolescence.	Sallis H et al.	—	2017	→
Gene-wide Association Study Reveals RNF122 Ubiquitin Ligase as a Novel Susceptibility Gene for Attention Deficit Hyperactivity Disorder.	Garcia-Martínez I et al.	—	2017	→
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.	Li Z et al.	—	2017	→
Genomewide association studies of suicide attempts in US soldiers.	Stein MB et al.	—	2017	→
Genotype-environment interaction on human cognitive function conditioned on the status of breastfeeding and maternal smoking around birth.	Lee SH et al.	—	2017	→
High resolution analysis of rare copy number variants in patients with autism spectrum disorder from Taiwan.	Chen CH et al.	—	2017	→
Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders.	Nguyen HT et al.	—	2017	→
Investigating the genetic underpinnings of early-life irritability.	Riglin L et al.	—	2017	→
Modulating Neuroinflammation to Treat Neuropsychiatric Disorders.	Radtke FA et al.	—	2017	→
Neurodevelopmental disease-associated de novo mutations and rare sequence variants affect TRIO GDP/GTP exchange factor activity.	Katrancha SM et al.	—	2017	→
Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain.	Barbash S et al.	—	2017	→
Neuroticism and the Overlap Between Autistic and ADHD Traits: Findings From a Population Sample of Young Adult Australian Twins.	Park SH et al.	—	2017	→
Optimal detection of weak positive latent dependence between two sequences of multiple tests.	Zhao SD et al.	—	2017	→
Pharmacogenomics in the treatment of mood disorders: Strategies and Opportunities for personalized psychiatry.	Amare AT et al.	—	2017	→
Post-mortem molecular profiling of three psychiatric disorders.	Ramaker RC et al.	—	2017	→
Psychiatric genetics - Does diagnosis matter?	Alda M	—	2017	→
Rare genetic variants in CX3CR1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders.	Ishizuka K et al.	—	2017	→
Reconsidering the prognosis of major depressive disorder across diagnostic boundaries: full recovery is the exception rather than the rule.	Verduijn J et al.	—	2017	→
Replication and characterization of <i>CADM2</i> and <i>MSRA</i> genes on human behavior.	Boutwell B et al.	—	2017	→
Schizophrenia genetics in the genome-wide era: a review of Japanese studies.	Kanazawa T et al.	—	2017	→
Sensory perception in autism.	Robertson CE et al.	—	2017	→
Speech and Language: Translating the Genome.	Deriziotis P et al.	—	2017	→
Statistical methods to detect pleiotropy in human complex traits.	Hackinger S et al.	—	2017	→
Structural Covariance Networks in Children with Autism or ADHD.	Bethlehem RAI et al.	—	2017	→
The neurodevelopmental origins of schizophrenia in the penumbra of genomic medicine.	Weinberger DR	—	2017	→
The use of behavioural genetics in the criminal justice system: A disability & human rights perspective.	O'Mahony C et al.	—	2017	→
Unraveling the biology of bipolar disorder using induced pluripotent stem-derived neurons.	Miller ND et al.	—	2017	→
Variation in global DNA hydroxymethylation with age associated with schizophrenia.	Jiang T et al.	—	2017	→
Whole genome sequencing in psychiatric disorders: the WGSPD consortium.	Sanders SJ et al.	—	2017	→