A genome-wide association study of alcohol dependence.
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- Authors
- Bierut, Laura J; Agrawal, Arpana; Bucholz, Kathleen K; Doheny, Kimberly F; Laurie, Cathy; Pugh, Elizabeth; Fisher, Sherri; Fox, Louis; Howells, William; Bertelsen, Sarah; Hinrichs, Anthony L; Almasy, Laura; Breslau, Naomi; Culverhouse, Robert C; Dick, Danielle M; Edenberg, Howard J; Foroud, Tatiana; Grucza, Richard A; Hatsukami, Dorothy; Hesselbrock, Victor; Johnson, Eric O; Kramer, John; Krueger, Robert F; Kuperman, Samuel; Lynskey, Michael; Mann, Karl; Neuman, Rosalind J; NΓΆthen, Markus M; Nurnberger, John I; Porjesz, Bernice; Ridinger, Monika; Saccone, Nancy L; Saccone, Scott F; Schuckit, Marc A; Tischfield, Jay A; Wang, Jen C; Rietschel, Marcella; Goate, Alison M; Rice, John P; Gene, Environment Association Studies Consortium
- Year
- 2010
- Journal
- Proceedings of the National Academy of Sciences of the United States of America
- PMID
- 20202923
- DOI
- 10.1073/pnas.0911109107
- PMCID
- PMC2841942
Excessive alcohol consumption is one of the leading causes of preventable death in the United States. Approximately 14% of those who use alcohol meet criteria during their lifetime for alcohol dependence, which is characterized by tolerance, withdrawal, inability to stop drinking, and continued drinking despite serious psychological or physiological problems. We explored genetic influences on alcohol dependence among 1,897 European-American and African-American subjects with alcohol dependence compared with 1,932 unrelated, alcohol-exposed, nondependent controls. Constitutional DNA of each subject was genotyped using the Illumina 1M beadchip. Fifteen SNPs yielded P < 10(-5), but in two independent replication series, no SNP passed a replication threshold of P < 0.05. Candidate gene GABRA2, which encodes the GABA receptor alpha2 subunit, was evaluated independently. Five SNPs at GABRA2 yielded nominal (uncorrected) P < 0.05, with odds ratios between 1.11 and 1.16. Further dissection of the alcoholism phenotype, to disentangle the influence of comorbid substance-use disorders, will be a next step in identifying genetic variants associated with alcohol dependence.
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|---|---|---|---|---|
| Epigenetic Dysregulation in Alcohol-Associated Behaviors: Preclinical and Clinical Evidence. | Domi E et al. | β | 2025 | β |
| Pleiotropic Effects of <i>Grm7</i>/<i>GRM7</i> in Shaping Neurodevelopmental Pathways and the Neural Substrate of Complex Behaviors and Disorders. | Gyetvai BM et al. | β | 2025 | β |
| Generalized genetic liability to substance use disorders. | Miller AP et al. | β | 2024 | β |
| Human genetics and epigenetics of alcohol use disorder. | Zhou H et al. | β | 2024 | β |
| Construction of copy number variation landscape and characterization of associated genes in a Bangladeshi cohort of neurodevelopmental disorders. | Akter H et al. | β | 2023 | β |
| Overlapping pathogenic de novo CNVs in neurodevelopmental disorders and congenital anomalies impacting constraint genes regulating early development. | Safizadeh Shabestari SA et al. | β | 2023 | β |
| The collaborative study on the genetics of alcoholism: Genetics. | Johnson EC et al. | β | 2023 | β |
| The first genome-wide association study of internet addiction; Revealed substantial shared risk factors with neurodevelopmental psychiatric disorders. | Haghighatfard A et al. | β | 2023 | β |
| GABA<sub>A</sub> receptor subtypes and benzodiazepine use, misuse, and abuse. | Engin E | β | 2022 | β |
| Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. | Lai D et al. | β | 2022 | β |
| Molecular Alterations Caused by Alcohol Consumption in the UK Biobank: A Mendelian Randomisation Study. | O'Farrell F et al. | β | 2022 | β |
| Prospective DNA Methylation Analysis of the CpG GABRA2 Receptor Subunit in Alcohol Dependence during Detoxification. | Preuss UW et al. | β | 2022 | β |
| Associations of CB1 cannabinoid receptor (CNR1) gene polymorphisms with risk for alcohol dependence: Evidence from meta-analyses of genetic and genome-wide association studies. | Pabalan N et al. | β | 2021 | β |
| Bibliometric Insights in Genetic Factors of Substance-Related Disorders: Intellectual Developments, Turning Points, and Emerging Trends. | Wang K et al. | β | 2021 | β |
| GABA<sub>A</sub> receptors in GtoPdb v.2021.3. | Belelli D et al. | β | 2021 | β |
| Genetic Basis of Dual Diagnosis: A Review of Genome-Wide Association Studies (GWAS) Focusing on Patients with Mood or Anxiety Disorders and Co-Occurring Alcohol-Use Disorders. | Stoychev K et al. | β | 2021 | β |
| Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. | Lai D et al. | β | 2021 | β |
| <i>LRRK2</i> Gene Variants Associated With a Higher Risk for Alcohol Dependence in Multiethnic Populations. | Oliveira PRS et al. | β | 2021 | β |
| Traumatic events during childhood and its risks to substance use in adulthood: an observational and genome-wide by environment interaction study in UK Biobank. | Cheng S et al. | β | 2021 | β |
| Whole Genome Interpretation for a Family of Five. | Corpas M et al. | β | 2021 | β |
| Will guidelines on alcohol consumption be personalized by a genetic approach? | Costanzo S et al. | β | 2021 | β |
| Epistatic evidence for gender-dependant slow neurotransmission signalling in substance use disorders: PPP1R12B versus PPP1R1B. | Liu K et al. | β | 2020 | β |
| Evaluating the Correlations Between Osteoporosis and Lifestyle-Related Factors Using Transcriptome-Wide Association Study. | Du Y et al. | β | 2020 | β |
| Genetic variants associated with alcohol dependence co-ordinate regulation of ADH genes in gastrointestinal and adipose tissues. | Hibberd R et al. | β | 2020 | β |
| Impact of Natural Occurring <i>ERAP1</i> Single Nucleotide Polymorphisms within miRNA-Binding Sites on HCMV Infection. | Melaiu O et al. | β | 2020 | β |
| On the path towards personalized medicine: Implications of pharmacogenetic studies of alcohol use disorder medications. | Nieto SJ et al. | β | 2020 | β |
| Recent advances in genetic studies of alcohol use disorders. | Gupta I et al. | β | 2020 | β |
| Regulation of GABA<sub>A</sub> Receptor Subunit Expression in Substance Use Disorders. | Barker JS et al. | β | 2020 | β |
| Analysis of a Sardinian Multiplex Family with Autism Spectrum Disorder Points to Post-Synaptic Density Gene Variants and Identifies <i>CAPG</i> as a Functionally Relevant Candidate Gene. | Bacchelli E et al. | β | 2019 | β |
| Association between polygenic risk for tobacco or alcohol consumption and liability to licit and illicit substance use in young Australian adults. | Chang LH et al. | β | 2019 | β |
| Associations between polygenic risk for tobacco and alcohol use and liability to tobacco and alcohol use, and psychiatric disorders in an independent sample of 13,999 Australian adults. | Chang LH et al. | β | 2019 | β |
| Associations of <i>BRAP</i> polymorphisms with the risk of alcohol dependence and scores on the Alcohol Use Disorders Identification Test. | Kim JW et al. | β | 2019 | β |
| CYP2A6 is associated with obesity: studies in human samples and a high fat diet mouse model. | Wang K et al. | β | 2019 | β |
| Genetic evidence for assortative mating on alcohol consumption in the UK Biobank. | Howe LJ et al. | β | 2019 | β |
| Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. | Lai D et al. | β | 2019 | β |
| Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. | Wetherill L et al. | β | 2019 | β |
| Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison. | Sun Y et al. | β | 2019 | β |
| GWAS and network analysis of co-occurring nicotine and alcohol dependence identifies significantly associated alleles and network. | Xiang B et al. | β | 2019 | β |
| GWAS of Behavioral Traits. | Mehta D et al. | β | 2019 | β |
| Intergenerational Effects of Alcohol: A Review of Paternal Preconception Ethanol Exposure Studies and Epigenetic Mechanisms in the Male Germline. | Rompala GR et al. | β | 2019 | β |
| Multisensory Environments to Measure Craving During Functional Magnetic Resonance Imaging. | Goodyear K | β | 2019 | β |
| Multivariate Analyses Reveal Biological Components Related to Neuronal Signaling and Immunity Mediating Electroencephalograms Abnormalities in Alcohol-Dependent Individuals from the Collaborative Study on the Genetics of Alcoholism Cohort. | Meda SA et al. | β | 2019 | β |
| National Institute on Drug Abuse genomics consortium white paper: Coordinating efforts between human and animal addiction studies. | Cates HM et al. | β | 2019 | β |
| Paternal Preconception Every-Other-Day Ethanol Drinking Alters Behavior and Ethanol Consumption in Offspring. | Beeler E et al. | β | 2019 | β |
| Predictive impact of rare genomic copy number variations in siblings of individuals with autism spectrum disorders. | D'Abate L et al. | β | 2019 | β |
| Relationships between substance abuse/dependence and psychiatric disorders based on polygenic scores. | GurriarΓ‘n X et al. | β | 2019 | β |
| Romantic Partner Alcohol Misuse Interacts with <i>GABRA2</i> Genotype to Predict Frequency of Drunkenness in Young Adulthood. | Gajos JM et al. | β | 2019 | β |
| Shared additive genetic variation for alcohol dependence among subjects of African and European ancestry. | Brick LA et al. | β | 2019 | β |
| Statistical Methods and Software for Substance Use and Dependence Genetic Research. | Lan T et al. | β | 2019 | β |
| The etiology of DSM-5 alcohol use disorder: Evidence of shared and non-shared additive genetic effects. | Palmer RHC et al. | β | 2019 | β |
| Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review. | Edenberg HJ et al. | β | 2018 | β |
| ANCO-GeneDB: annotations and comprehensive analysis of candidate genes for alcohol, nicotine, cocaine and opioid dependence. | Hu R et al. | β | 2018 | β |
| An efficient genome-wide association test for mixed binary and continuous phenotypes with applications to substance abuse research. | Buu A et al. | β | 2018 | β |
| A test for gene-environment interaction in the presence of measurement error in the environmental variable. | Aschard H et al. | β | 2018 | β |
| A univariate perspective of multivariate genome-wide association analysis. | Guo X et al. | β | 2018 | β |
| Full genetic analysis for genome-wide association study of Fangji: a powerful approach for effectively dissecting the molecular architecture of personalized traditional Chinese medicine. | Chen G et al. | β | 2018 | β |
| GABA<sub>A</sub> receptor polymorphisms in alcohol use disorder in the GWAS era. | Koulentaki M et al. | β | 2018 | β |
| GABRA2, alcohol, and illicit drug use: An event-level model of genetic risk for polysubstance use. | Mallard TT et al. | β | 2018 | β |
| GABRA2 rs279858-linked variants are associated with disrupted structural connectome of reward circuits in heroin abusers. | Sun Y et al. | β | 2018 | β |
| Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells? | Prytkova I et al. | β | 2018 | β |
| Genetic variants of <i>ALDH2</i>-rs671 and <i>CYP2E1</i>-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population. | Ye X et al. | β | 2018 | β |
| Genome-wide association study identifies a novel locus for cannabis dependence. | Agrawal A et al. | β | 2018 | β |
| Genomewide association study of HLA alloimmunization in previously pregnant blood donors. | Seielstad M et al. | β | 2018 | β |
| Glycogen synthase kinase 3 beta regulates ethanol consumption and is a risk factor for alcohol dependence. | van der Vaart A et al. | β | 2018 | β |
| GWAS summary-based pathway analysis correcting for the genetic confounding impact of environmental exposures. | Fan Q et al. | β | 2018 | β |
| Human Genetics of Addiction: New Insights and Future Directions. | Hancock DB et al. | β | 2018 | β |
| OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome. | Uddin M et al. | β | 2018 | β |
| Post-GWAS in Psychiatric Genetics: A Developmental Perspective on the "Other" Next Steps. | Dick DM et al. | β | 2018 | β |
| Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations. | Almli LM et al. | β | 2018 | β |
| Residuals and Diagnostics for Ordinal Regression Models: A Surrogate Approach. | Liu D et al. | β | 2018 | β |
| Sex and Ξ²-Endorphin Influence the Effects of Ethanol on Limbic <i>Gabra2</i> Expression in a Mouse Binge Drinking Model. | Rhinehart EM et al. | β | 2018 | β |
| The Arf6 activator Efa6/PSD3 confers regional specificity and modulates ethanol consumption in Drosophila and humans. | Gonzalez DA et al. | β | 2018 | β |
| The major depressive disorder GWAS-supported variant rs10514299 in TMEM161B-MEF2C predicts putamen activation during reward processing in alcohol dependence. | Muench C et al. | β | 2018 | β |
| A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model. | Nassan M et al. | β | 2017 | β |
| Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes. | Xu H et al. | β | 2017 | β |
| An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count. | Chen G et al. | β | 2017 | β |
| Association between substance use disorder and polygenic liability to schizophrenia | Hartz SM et al. | β | 2017 | β |
| Association Between Substance Use Disorder and Polygenic Liability to Schizophrenia. | Hartz SM et al. | β | 2017 | β |
| Blunted Dopamine Transmission in Addiction: Potential Mechanisms and Implications for Behavior. | Trifilieff P et al. | β | 2017 | β |
| Enhancing VTA Ca<sub>v</sub>1.3 L-type Ca<sup>2+</sup> channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. | MartΓnez-Rivera A et al. | β | 2017 | β |
| Examination of the Involvement of Cholinergic-Associated Genes in Nicotine Behaviors in European and African Americans. | Melroy-Greif WE et al. | β | 2017 | β |
| GABA<sub>A</sub> receptor subtype involvement in addictive behaviour. | Stephens DN et al. | β | 2017 | β |
| Genetics of alcohol consumption in Drosophila melanogaster. | Fochler S et al. | β | 2017 | β |
| Genetic studies of alcohol dependence in the context of the addiction cycle. | Reilly MT et al. | β | 2017 | β |
| Genetic variation and epigenetic modification of the prodynorphin gene in peripheral blood cells in alcoholism. | D'Addario C et al. | β | 2017 | β |
| Genome-wide association study of body mass index in subjects with alcohol dependence. | Polimanti R et al. | β | 2017 | β |
| Genome-wide meta-analysis identifies a novel susceptibility signal at CACNA2D3 for nicotine dependence. | Yin X et al. | β | 2017 | β |
| Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students. | Webb BT et al. | β | 2017 | β |
| Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence. | Andersen AM et al. | β | 2017 | β |
| Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension. | Owusu D et al. | β | 2017 | β |
| Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models. | Rinker JA et al. | β | 2017 | β |
| Review: Genetic research on alcohol use outcomes in African American populations: A review of the literature, associated challenges, and implications. | Dick DM et al. | β | 2017 | β |
| Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population. | Wen L et al. | β | 2017 | β |
| SNP by SNP by environment interaction network of alcoholism. | Zollanvari A et al. | β | 2017 | β |
| The genetic epidemiology of substance use disorder: A review. | Prom-Wormley EC et al. | β | 2017 | β |
| The genetics of alcohol dependence and alcohol-related liver disease. | Stickel F et al. | β | 2017 | β |
| Two novel candidate genes identified in adults from the Newfoundland population with addictive tendencies towards food. | Pedram P et al. | β | 2017 | β |
| Variable phenotype expression in a family segregating microdeletions of the <i>NRXN1</i> and <i>MBD5</i> autism spectrum disorder susceptibility genes. | Woodbury-Smith M et al. | β | 2017 | β |
| A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction. | Bell RL et al. | β | 2016 | β |
| An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function. | Yang JJ et al. | β | 2016 | β |
| A Review of Genome-Wide Association Studies of Stimulant and Opioid Use Disorders. | Jensen KP | β | 2016 | β |
| Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. | Schwantes-An TH et al. | β | 2016 | β |
| Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement. | Carey CE et al. | β | 2016 | β |
| Association Study of Gene Polymorphisms in GABA, Serotonin, Dopamine, and Alcohol Metabolism Pathways with Alcohol Dependence in Taiwanese Han Men. | Wu LS et al. | β | 2016 | β |
| A Test-Replicate Approach to Candidate Gene Research on Addiction and Externalizing Disorders: A Collaboration Across Five Longitudinal Studies. | Samek DR et al. | β | 2016 | β |
| Detecting Gene-Gene Interactions Associated with Multiple Complex Traits with U-Statistics. | Li M et al. | β | 2016 | β |
| Effects of Gabra2 Point Mutations on Alcohol Intake: Increased Binge-Like and Blunted Chronic Drinking by Mice. | Newman EL et al. | β | 2016 | β |
| Ethnicity and Psychiatric Disorders. | Hawes AM et al. | β | 2016 | β |
| Evidence of CNIH3 involvement in opioid dependence. | Nelson EC et al. | β | 2016 | β |
| Exploration of a Polygenic Risk Score for Alcohol Consumption: A Longitudinal Analysis from the ALSPAC Cohort. | Taylor M et al. | β | 2016 | β |
| Genetic imaging consortium for addiction medicine: From neuroimaging to genes. | Mackey S et al. | β | 2016 | β |
| Genetic mapping of canine fear and aggression. | Zapata I et al. | β | 2016 | β |
| Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures. | Kapoor M et al. | β | 2016 | β |
| Genome-wide rare copy number variations contribute to genetic risk for transposition of the great arteries. | Costain G et al. | β | 2016 | β |
| High Resolution Genomic Scans Reveal Genetic Architecture Controlling Alcohol Preference in Bidirectionally Selected Rat Model. | Lo CL et al. | β | 2016 | β |
| Indexing Effects of Copy Number Variation on Genes Involved in Developmental Delay. | Uddin M et al. | β | 2016 | β |
| Modeling Multiple Responses via Bootstrapping Margins with an Application to Genetic Association Testing. | Zhao J et al. | β | 2016 | β |
| Modeling X Chromosome Data Using Random Forests: Conquering Sex Bias. | Winham SJ et al. | β | 2016 | β |
| Overview of the Genetics of Alcohol Use Disorder. | Tawa EA et al. | β | 2016 | β |
| Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence. | Zuo L et al. | β | 2016 | β |
| Small Heat Shock Proteins Are Novel Common Determinants of Alcohol and Nicotine Sensitivity in Caenorhabditis elegans. | Johnson JR et al. | β | 2016 | β |
| Test for association of common variants in GRM7 with alcohol consumption. | Melroy-Greif WE et al. | β | 2016 | β |
| The 22q11 PRODH/DGCR6 deletion is frequent in hyperprolinemic subjects but is not a strong risk factor for ASD. | Richard AC et al. | β | 2016 | β |
| The association of HTR3A mRNA expression and craving in Han Chinese alcohol-dependent patients: a preliminary study. | Xu YH et al. | β | 2016 | β |
| 11q24.2-25 micro-rearrangements in autism spectrum disorders: Relation to brain structures. | Maruani A et al. | β | 2015 | β |
| [A genetic view of addiction]. | Ramoz N et al. | β | 2015 | β |
| A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. | Buch S et al. | β | 2015 | β |
| Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. | Hart AB et al. | β | 2015 | β |
| A New Genomewide Association Meta-Analysis of Alcohol Dependence. | Zuo L et al. | β | 2015 | β |
| Are genetic variants for tobacco smoking associated with cannabis involvement? | Agrawal A et al. | β | 2015 | β |
| Association of GABAA receptor Ξ±2 subunit gene (GABRA2) with alcohol dependence-related aggressive behavior. | Strac DS et al. | β | 2015 | β |
| Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent. | Winham SJ et al. | β | 2015 | β |
| Candidate gene study for smoking, alcohol use, and body weight in a sample of pregnant women. | Wehby GL et al. | β | 2015 | β |
| Clinically relevant copy number variations detected in cerebral palsy. | Oskoui M et al. | β | 2015 | β |
| Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms. | Manzardo AM et al. | β | 2015 | β |
| Commentary: sex differences in the pathways to symptoms of alcohol use disorder: a study of opposite-sex twin pairs. | Kapoor M et al. | β | 2015 | β |
| Common single nucleotide variants underlying drug addiction: more than a decade of research. | BΓΌhler KM et al. | β | 2015 | β |
| COMT Associations with Disordered Gambling and Drinking Measures. | Guillot CR et al. | β | 2015 | β |
| CREB-BDNF pathway influences alcohol cue-elicited activation in drinkers. | Chen J et al. | β | 2015 | β |
| DAT1 and Alcohol Use: Differential Responses to Life Stress during Adolescence. | Stogner JM | β | 2015 | β |
| Dissecting ancestry genomic background in substance dependence genome-wide association studies. | Polimanti R et al. | β | 2015 | β |
| Drinking beyond a lifetime: New and emerging insights into paternal alcohol exposure on subsequent generations. | Finegersh A et al. | β | 2015 | β |
| Gene-based and pathway-based genome-wide association study of alcohol dependence. | Zuo L et al. | β | 2015 | β |
| Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking. | McClintick JN et al. | β | 2015 | β |
| Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population. | Way M et al. | β | 2015 | β |
| Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations. | Wang KS et al. | β | 2015 | β |
| Genome-wide association analysis on five isolated populations identifies variants of the HLA-DOA gene associated with white wine liking. | Pirastu N et al. | β | 2015 | β |
| Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. | Peprah E et al. | β | 2015 | β |
| Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. | Xu K et al. | β | 2015 | β |
| Genome-Wide Association Study of Behavioral Disinhibition in a Selected Adolescent Sample. | Derringer J et al. | β | 2015 | β |
| Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood. | Adkins DE et al. | β | 2015 | β |
| Genomic influences on alcohol problems in a population-based sample of young adults. | Edwards AC et al. | β | 2015 | β |
| Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. | Carey CE et al. | β | 2015 | β |
| Performance of case-control rare copy number variation annotation in classification of autism. | Engchuan W et al. | β | 2015 | β |
| Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila. | Morozova TV et al. | β | 2015 | β |
| Potential relationship between single nucleotide polymorphisms used in forensic genetics and diseases or other traits in European population. | Pombar-Gomez M et al. | β | 2015 | β |
| Risky Business: Pathways to Progress in Biologically Informed Studies of Psychopathology. | Agrawal A et al. | β | 2015 | β |
| Rsu1 regulates ethanol consumption in Drosophila and humans. | Ojelade SA et al. | β | 2015 | β |
| Shared additive genetic influences on DSM-IV criteria for alcohol dependence in subjects of European ancestry. | Palmer RH et al. | β | 2015 | β |
| Testing for polygenic effects in genome-wide association studies. | Pan W et al. | β | 2015 | β |
| The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence. | Suchankova P et al. | β | 2015 | β |
| The phenotypic manifestations of rare genic CNVs in autism spectrum disorder. | Merikangas AK et al. | β | 2015 | β |
| Using extended pedigrees to identify novel autism spectrum disorder (ASD) candidate genes. | Woodbury-Smith M et al. | β | 2015 | β |
| XRCC5 as a risk gene for alcohol dependence: evidence from a genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans. | Juraeva D et al. | β | 2015 | β |
| A CTNNA3 compound heterozygous deletion implicates a role for Ξ±T-catenin in susceptibility to autism spectrum disorder. | Bacchelli E et al. | β | 2014 | β |
| A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. | Oei L et al. | β | 2014 | β |
| A non-parametric approach for detecting gene-gene interactions associated with age-at-onset outcomes. | Li M et al. | β | 2014 | β |
| Association and interaction analyses of 5-HT3 receptor and serotonin transporter genes with alcohol, cocaine, and nicotine dependence using the SAGE data. | Yang J et al. | β | 2014 | β |
| Association between copy number variation losses and alcohol dependence across African American and European American ethnic groups. | Ulloa AE et al. | β | 2014 | β |
| Association between DPYSL2 gene polymorphisms and alcohol dependence in Caucasian samples. | Taylor A et al. | β | 2014 | β |
| Association of GATA4 sequence variation with alcohol dependence. | Karpyak VM et al. | β | 2014 | β |
| Biological overlap of attention-deficit/hyperactivity disorder and autism spectrum disorder: evidence from copy number variants. | Martin J et al. | β | 2014 | β |
| Brain Ξ³-aminobutyric acid: a neglected role in impulsivity. | Hayes DJ et al. | β | 2014 | β |
| CHD2 haploinsufficiency is associated with developmental delay, intellectual disability, epilepsy and neurobehavioural problems. | ChΓ©nier S et al. | β | 2014 | β |
| Cognitive mediators and disparities in the relation between teen depressiveness and smoking. | Mistry R et al. | β | 2014 | β |
| Common PTP4A1-PHF3-EYS variants are specific for alcohol dependence. | Zuo L et al. | β | 2014 | β |
| Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. | Pinto D et al. | β | 2014 | β |
| Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. | McGrath LM et al. | β | 2014 | β |
| DSM-5 cannabis use disorder: a phenotypic and genomic perspective. | Agrawal A et al. | β | 2014 | β |
| Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression. | McClintick JN et al. | β | 2014 | β |
| Examination of genetic variation in GABRA2 with conduct disorder and alcohol abuse and dependence in a longitudinal study. | Melroy WE et al. | β | 2014 | β |
| Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. | Yang C et al. | β | 2014 | β |
| Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood. | Dick DM et al. | β | 2014 | β |
| Genetics and genomics of alcohol sensitivity. | Morozova TV et al. | β | 2014 | β |
| Genetics of alcohol dependence: a review of clinical studies. | Samochowiec J et al. | β | 2014 | β |
| Genetics of alcoholism. | Edenberg HJ et al. | β | 2014 | β |
| Genetics of alcoholism. | Iyer-Eimerbrink PA et al. | β | 2014 | β |
| Genome-wide association discoveries of alcohol dependence. | Zuo L et al. | β | 2014 | β |
| Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. | Gelernter J et al. | β | 2014 | β |
| Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. | Kapoor M et al. | β | 2014 | β |
| Have the genetics of cannabis involvement gone to pot? | Agrawal A et al. | β | 2014 | β |
| Identifying Genetic Variants for Addiction via Propensity Score Adjusted Generalized Kendall's Tau. | Jiang Y et al. | β | 2014 | β |
| Investigation of maternal genotype effects in autism by genome-wide association. | Yuan H et al. | β | 2014 | β |
| Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans. | Culverhouse RC et al. | β | 2014 | β |
| Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders. | Kos MZ et al. | β | 2014 | β |
| On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis. | Peterson RE et al. | β | 2014 | β |
| Outfoxed by RBFOX1-a caution about ascertainment bias. | Kamien B et al. | β | 2014 | β |
| Paternal alcohol exposure reduces alcohol drinking and increases behavioral sensitivity to alcohol selectively in male offspring. | Finegersh A et al. | β | 2014 | β |
| Perspectives on the neuroscience of alcohol from the National Institute on Alcohol Abuse and Alcoholism. | Reilly MT et al. | β | 2014 | β |
| Recurrent duplications of the annexin A1 gene (ANXA1) in autism spectrum disorders. | Correia CT et al. | β | 2014 | β |
| Shared genetic factors influence risk for bipolar disorder and alcohol use disorders. | Carmiol N et al. | β | 2014 | β |
| Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations. | Wang S et al. | β | 2014 | β |
| TARV: tree-based analysis of rare variants identifying risk modifying variants in CTNNA2 and CNTNAP2 for alcohol addiction. | Song C et al. | β | 2014 | β |
| The Genetics, Neurogenetics and Pharmacogenetics of Addiction. | Demers CH et al. | β | 2014 | β |
| Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. | Yan J et al. | β | 2014 | β |
| Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy. | Sadler B et al. | β | 2014 | β |
| A bivariate mann-whitney approach for unraveling genetic variants and interactions contributing to comorbidity. | Wen Y et al. | β | 2013 | β |
| A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. | Wang JC et al. | β | 2013 | β |
| Alcohol consumption in men is influenced by qualitatively different genetic factors in adolescence and adulthood. | Edwards AC et al. | β | 2013 | β |
| A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks. | Kapoor M et al. | β | 2013 | β |
| Association of functional DBH genetic variants with alcohol dependence risk and related depression and suicide attempt phenotypes: results from a large multicenter association study. | Preuss UW et al. | β | 2013 | β |
| Association of the ALDH1A1*2 promoter polymorphism with alcohol phenotypes in young adults with or without ALDH2*2. | Otto JM et al. | β | 2013 | β |
| Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states. | Karpyak VM et al. | β | 2013 | β |
| Association of VMAT2 gene polymorphisms with alcohol dependence. | Fehr C et al. | β | 2013 | β |
| A Weighted Random Forests Approach to Improve Predictive Performance. | Winham SJ et al. | β | 2013 | β |
| Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. | Kos MZ et al. | β | 2013 | β |
| Common variants at 12q24 are associated with drinking behavior in Han Chinese. | Yang X et al. | β | 2013 | β |
| Common variants in HLA-DRA gene are associated with alcohol dependence in two Caucasian samples. | Pan Y et al. | β | 2013 | β |
| Deletions in 16q24.2 are associated with autism spectrum disorder, intellectual disability and congenital renal malformation. | Handrigan GR et al. | β | 2013 | β |
| Effect of homozygous deletions at 22q13.1 on alcohol dependence severity and cue-elicited BOLD response in the precuneus. | Liu J et al. | β | 2013 | β |
| Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence. | Zuo L et al. | β | 2013 | β |
| Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication. | Park BL et al. | β | 2013 | β |
| Functional characterization of SNPs in CHRNA3/B4 intergenic region associated with drug behaviors. | Flora AV et al. | β | 2013 | β |
| Gene-environment interaction in problematic substance use: interaction between DRD4 and insecure attachments. | Olsson CA et al. | β | 2013 | β |
| Genetic association test for multiple traits at gene level. | Guo X et al. | β | 2013 | β |
| Genetic influences on craving for alcohol. | Agrawal A et al. | β | 2013 | β |
| Genetic influences on the development of alcoholism. | Enoch MA | β | 2013 | β |
| Genetics and epigenetics of alcohol dependence. | Nieratschker V et al. | β | 2013 | β |
| Genetic variants in the fat mass- and obesity-associated (FTO) gene are associated with alcohol dependence. | Wang L et al. | β | 2013 | β |
| Genome-wide association studies of maximum number of drinks. | Pan Y et al. | β | 2013 | β |
| Genome-wide DNA methylation analysis in alcohol dependence. | Zhang R et al. | β | 2013 | β |
| Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence. | Biernacka JM et al. | β | 2013 | β |
| Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence. | Zuo L et al. | β | 2013 | β |
| Genotyping of single nucleotide polymorphisms by melting curve analysis using thin film semi-transparent heaters integrated in a lab-on-foil system. | Ohlander A et al. | β | 2013 | β |
| GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. | Rietveld CA et al. | β | 2013 | β |
| Imputation across genotyping arrays for genome-wide association studies: assessment of bias and a correction strategy. | Johnson EO et al. | β | 2013 | β |
| Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. | Han S et al. | β | 2013 | β |
| Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. | Zhou Z et al. | β | 2013 | β |
| Molecular and genetic determinants of alcohol dependence. | Awofala AA | β | 2013 | β |
| NCK2 is significantly associated with opiates addiction in African-origin men. | Liu Z et al. | β | 2013 | β |
| NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. | Zuo L et al. | β | 2013 | β |
| Polymorphisms of genes in neurotransmitter systems were associated with alcohol use disorders in a Tibetan population. | Xu Y et al. | β | 2013 | β |
| Rare ADH variant constellations are specific for alcohol dependence. | Zuo L et al. | β | 2013 | β |
| Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent. | Zuo L et al. | β | 2013 | β |
| Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C. | Biernacka JM et al. | β | 2013 | β |
| Sex chromosome-wide association analysis suggested male-specific risk genes for alcohol dependence. | Zuo L et al. | β | 2013 | β |
| Significant association of CHRNB3 variants with nicotine dependence in multiple ethnic populations. | Cui WY et al. | β | 2013 | β |
| Stress-response pathways are altered in the hippocampus of chronic alcoholics. | McClintick JN et al. | β | 2013 | β |
| TACR1 genotypes predict fMRI response to alcohol cues and level of alcohol dependence. | Blaine S et al. | β | 2013 | β |
| The case-only test for gene-environment interaction is not uniformly powerful: an empirical example. | Wu C et al. | β | 2013 | β |
| The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G Γ E effects. | Ray LA et al. | β | 2013 | β |
| The genetics of alcohol dependence. | Rietschel M et al. | β | 2013 | β |
| Transcriptome study of differential expression in schizophrenia. | Sanders AR et al. | β | 2013 | β |
| Voluntary intravenous self-administration of alcohol detects an interaction between GABAergic manipulation and GABRG1 polymorphism genotype: a pilot study. | Plawecki MH et al. | β | 2013 | β |
| Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption. | Vanderlinden LA et al. | β | 2013 | β |
| ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry. | Bierut LJ et al. | β | 2012 | β |
| A discovery resource of rare copy number variations in individuals with autism spectrum disorder. | Prasad A et al. | β | 2012 | β |
| Alcohol Dependence and Genes Encoding Ξ±2 and Ξ³1 GABAA Receptor Subunits: Insights from Humans and Mice. | Borghese CM et al. | β | 2012 | β |
| Alcohol intake. | Corella D | β | 2012 | β |
| ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies. | Wang KS et al. | β | 2012 | β |
| A novel locus for body mass index on 5p15.2: a meta-analysis of two genome-wide association studies. | Wang KS et al. | β | 2012 | β |
| Chloride intracellular channels modulate acute ethanol behaviors in Drosophila, Caenorhabditis elegans and mice. | Bhandari P et al. | β | 2012 | β |
| Chronic alcohol exposure alters gene expression in HepG2 cells. | Pochareddy S et al. | β | 2012 | β |
| Chronic tiagabine administration and aggressive responding in individuals with a history of substance abuse and antisocial behavior. | Gowin JL et al. | β | 2012 | β |
| Clinical indices of familial alcohol use disorder. | Kendler KS et al. | β | 2012 | β |
| Convergence of genome-wide association and candidate gene studies for alcoholism. | Olfson E et al. | β | 2012 | β |
| Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. | Lin P et al. | β | 2012 | β |
| DNA methylation patterns in alcoholics and family controls. | Thapar M et al. | β | 2012 | β |
| Evidence for multiple genetic factors underlying the DSM-IV criteria for alcohol dependence. | Kendler KS et al. | β | 2012 | β |
| Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumption. | McBride WJ et al. | β | 2012 | β |
| Genetic architectures of psychiatric disorders: the emerging picture and its implications. | Sullivan PF et al. | β | 2012 | β |
| Genetics of dopamine receptors and drug addiction. | Gorwood P et al. | β | 2012 | β |
| Genetics of GABAergic signaling in nicotine and alcohol dependence. | Cui WY et al. | β | 2012 | β |
| Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence. | Karpyak VM et al. | β | 2012 | β |
| Genetic variations in the dopaminergic system and alcohol use: a system-level analysis. | Chen C et al. | β | 2012 | β |
| Genome-environmental risk assessment of cocaine dependence. | Wei C et al. | β | 2012 | β |
| Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms. | Wang KS et al. | β | 2012 | β |
| Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. | Zuo L et al. | β | 2012 | β |
| Genome-wide association study of comorbid depressive syndrome and alcohol dependence. | Edwards AC et al. | β | 2012 | β |
| Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence. | Zuo L et al. | β | 2012 | β |
| Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. | Frank J et al. | β | 2012 | β |
| Identifying gene networks underlying the neurobiology of ethanol and alcoholism. | Wolen AR et al. | β | 2012 | β |
| Identifying genetic variation for alcohol dependence. | Agrawal A et al. | β | 2012 | β |
| Implications of central immune signaling caused by drugs of abuse: mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence. | Coller JK et al. | β | 2012 | β |
| Large scale association analysis for drug addiction: results from SNP to gene. | Guo X et al. | β | 2012 | β |
| Levels of explanation in psychiatric and substance use disorders: implications for the development of an etiologically based nosology. | Kendler KS | β | 2012 | β |
| Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges. | Agrawal A et al. | β | 2012 | β |
| Meta-analysis of genome-wide association studies for personality. | de Moor MH et al. | β | 2012 | β |
| Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways. | Harari O et al. | β | 2012 | β |
| PKNOX2 is associated with formal thought disorder in schizophrenia: a meta-analysis of two genome-wide association studies. | Wang KS et al. | β | 2012 | β |
| Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence. | Wang KS et al. | β | 2012 | β |
| Rare deletions at the neurexin 3 locus in autism spectrum disorder. | Vaags AK et al. | β | 2012 | β |
| Recent advances in the genetic epidemiology and molecular genetics of substance use disorders. | Kendler KS et al. | β | 2012 | β |
| Serotonin transporter genomic biomarker for quantitative assessment of ondansetron treatment response in alcoholics. | Seneviratne C et al. | β | 2012 | β |
| Severe intellectual disability and autistic features associated with microduplication 2q23.1. | Chung BH et al. | β | 2012 | β |
| SHANK1 Deletions in Males with Autism Spectrum Disorder. | Sato D et al. | β | 2012 | β |
| SNP interaction detection with Random Forests in high-dimensional genetic data. | Winham SJ et al. | β | 2012 | β |
| Stable genetic effects on symptoms of alcohol abuse and dependence from adolescence into early adulthood. | van Beek JH et al. | β | 2012 | β |
| The aggregate effect of dopamine genes on dependence symptoms among cocaine users: cross-validation of a candidate system scoring approach. | Derringer J et al. | β | 2012 | β |
| The dappled nature of causes of psychiatric illness: replacing the organic-functional/hardware-software dichotomy with empirically based pluralism. | Kendler KS | β | 2012 | β |
| The genetic basis of addictive disorders. | Ducci F et al. | β | 2012 | β |
| The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. | Morozova TV et al. | β | 2012 | β |
| The genetic effect of copy number variations on the risk of alcoholism in a Korean population. | Bae JS et al. | β | 2012 | β |
| The genetics of addiction-a translational perspective. | Agrawal A et al. | β | 2012 | β |
| The genetics of alcohol dependence: advancing towards systems-based approaches. | Palmer RH et al. | β | 2012 | β |
| The genetics of substance dependence. | Wang JC et al. | β | 2012 | β |
| A candidate gene association study of alcohol consumption in young women. | Agrawal A et al. | β | 2011 | β |
| A genome-wide association study of DSM-IV cannabis dependence. | Agrawal A et al. | β | 2011 | β |
| A genotype resource for postmortem brain samples from the Autism Tissue Program. | Wintle RF et al. | β | 2011 | β |
| A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. | Wang KS et al. | β | 2011 | β |
| An Interdisciplinary Approach to Studying Gene-Environment Interactions: From Twin Studies to Gene Identification and Back. | Dick DM | β | 2011 | β |
| A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. | Zuo L et al. | β | 2011 | β |
| A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. | Heath AC et al. | β | 2011 | β |
| Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. | Breese GR et al. | β | 2011 | β |
| Common and rare variants in alcohol dependence. | Edenberg HJ | β | 2011 | β |
| Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population. | Takeuchi F et al. | β | 2011 | β |
| Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder. | Lydall GJ et al. | β | 2011 | β |
| Copy number variation accuracy in genome-wide association studies. | Lin P et al. | β | 2011 | β |
| Do common variants play a role in risk for autism? Evidence and theoretical musings. | Devlin B et al. | β | 2011 | β |
| Dorsolateral prefrontal Ξ³-aminobutyric acid in men predicts individual differences in rash impulsivity. | Boy F et al. | β | 2011 | β |
| Efficient replication of over 180 genetic associations with self-reported medical data. | Tung JY et al. | β | 2011 | β |
| Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study. | Wang KS et al. | β | 2011 | β |
| Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence. | Lydall GJ et al. | β | 2011 | β |
| Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study. | Dumitrescu L et al. | β | 2011 | β |
| Genetics of alcohol dependence. | Kimura M et al. | β | 2011 | β |
| Genetic vulnerability and susceptibility to substance dependence. | Bierut LJ | β | 2011 | β |
| Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample. | Kendler KS et al. | β | 2011 | β |
| Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. | Schumann G et al. | β | 2011 | β |
| Genome-wide association studies of alcohol dependence and substance use disorders. | Treutlein J et al. | β | 2011 | β |
| Genome-wide association studies of alcohol intake--a promising cocktail? | Agrawal A et al. | β | 2011 | β |
| Genome-wide association study of conduct disorder symptomatology. | Dick DM et al. | β | 2011 | β |
| Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence. | Johnson C et al. | β | 2011 | β |
| Glypican Gene GPC5 Participates in the Behavioral Response to Ethanol: Evidence from Humans, Mice, and Fruit Flies. | Joslyn G et al. | β | 2011 | β |
| Hemizygous deletions on chromosome 1p21.3 involving the DPYD gene in individuals with autism spectrum disorder. | Carter MT et al. | β | 2011 | β |
| Heritability of problem drinking and the genetic overlap with personality in a general population sample. | de Moor MH et al. | β | 2011 | β |
| Identifying neurobiological phenotypes associated with alcohol use disorder severity. | Claus ED et al. | β | 2011 | β |
| Is the reduction of dimensionality to a small number of features always necessary in constructing predictive models for analysis of complex diseases or behaviours? | Zollanvari A et al. | β | 2011 | β |
| Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence. | Cosgrove KP et al. | β | 2011 | β |
| Nonreplication of an association of SGIP1 SNPs with alcohol dependence and resting theta EEG power. | Derringer J et al. | β | 2011 | β |
| Rare familial 16q21 microdeletions under a linkage peak implicate cadherin 8 (CDH8) in susceptibility to autism and learning disability. | Pagnamenta AT et al. | β | 2011 | β |
| "Replicated" genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs. | Drgon T et al. | β | 2011 | β |
| Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases. | Li D et al. | β | 2011 | β |
| The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data. | Middeldorp CM et al. | β | 2011 | β |
| A genome-wide scan for common alleles affecting risk for autism. | Anney R et al. | β | 2010 | β |
| An integrated genome research network for studying the genetics of alcohol addiction. | Spanagel R et al. | β | 2010 | β |
| Functional impact of global rare copy number variation in autism spectrum disorders. | Pinto D et al. | β | 2010 | β |
| Genetic research: who is at risk for alcoholism. | Foroud T et al. | β | 2010 | β |
| Predicting sensation seeking from dopamine genes. A candidate-system approach. | Derringer J et al. | β | 2010 | β |