Genome-wide search for genes affecting the risk for alcohol dependence.
paper
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- Authors
- Reich, T; Edenberg, H J; Goate, A; Williams, J T; Rice, J P; Van Eerdewegh, P; Foroud, T; Hesselbrock, V; Schuckit, M A; Bucholz, K; Porjesz, B; Li, T K; Conneally, P M; Nurnberger, J I; Tischfield, J A; Crowe, R R; Cloninger, C R; Wu, W; Shears, S; Carr, K; Crose, C; Willig, C; Begleiter, H
- Year
- 1998
- Journal
- American journal of medical genetics
- PMID
- 9603606
- DOI
- 10.1002/(SICI)1096-8628(19980508)81:3<207::AID-AJMG1>3.0.CO;2-T
Alcohol dependence is a leading cause of morbidity and premature death. Several lines of evidence suggest a substantial genetic component to the risk for alcoholism: sibs of alcoholic probands have a 3-8 fold increased risk of also developing alcoholism, and twin heritability estimates of 50-60% are reported by contemporary studies of twins. We report on the results of a six-center collaborative study to identify susceptibility loci for alcohol dependence. A genome-wide screen examined 291 markers in 987 individuals from 105 families. Two-point and multipoint nonparametric linkage analyses were performed to detect susceptibility loci for alcohol dependence. Multipoint methods provided the strongest suggestions of linkage with susceptibility loci for alcohol dependence on chromosomes 1 and 7, and more modest evidence for a locus on chromosome 2. In addition, there was suggestive evidence for a protective locus on chromosome 4 near the alcohol dehydrogenase genes, for which protective effects have been reported in Asian populations.
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Comparing Transdiagnostic Risk Factors: Predicting Emergence of Significant Depressive, Anxiety, and Substance Abuse Symptoms Among Juvenile Delinquents. | Klein RJ et al. | β | 2026 | β |
| Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations. | Paul SE et al. | β | 2024 | β |
| Examining associations between genetic and neural risk for externalizing behaviors in adolescence and early adulthood. | Brislin SJ et al. | β | 2024 | β |
| GABAergic mechanisms in alcohol dependence. | Uusi-Oukari M et al. | β | 2024 | β |
| Human genetics and epigenetics of alcohol use disorder. | Zhou H et al. | β | 2024 | β |
| Association of parental divorce, discord, and polygenic risk with children's alcohol initiation and lifetime risk for alcohol use disorder. | Kuo SI et al. | β | 2023 | β |
| Associations Between Cannabis Use, Polygenic Liability for Schizophrenia, and Cannabis-related Experiences in a Sample of Cannabis Users. | Johnson EC et al. | β | 2023 | β |
| Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders. | Saenz de Viteri S et al. | β | 2023 | β |
| Polygenic Contributions to Suicidal Thoughts and Behaviors in a Sample Ascertained for Alcohol Use Disorders. | Colbert SMC et al. | β | 2023 | β |
| Risk of parental major psychiatric disorders in patients with comorbid autism spectrum disorder and attention deficit hyperactivity disorder: A population-based family-link study. | Hsu TW et al. | β | 2023 | β |
| The collaborative study on the genetics of alcoholism: Brain function. | Meyers JL et al. | β | 2023 | β |
| The collaborative study on the genetics of alcoholism: Genetics. | Johnson EC et al. | β | 2023 | β |
| The Collaborative Study on the Genetics of Alcoholism: Overview. | Agrawal A et al. | β | 2023 | β |
| The collaborative study on the genetics of alcoholism: Sample and clinical data. | Dick DM et al. | β | 2023 | β |
| Alcohol use disorder, psychiatric comorbidities, marriage and divorce in a high-risk sample. | Thomas NS et al. | β | 2022 | β |
| Evaluating risk for alcohol use disorder: Polygenic risk scores and family history. | Lai D et al. | β | 2022 | β |
| Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. | Lai D et al. | β | 2022 | β |
| Non-coding RNA in alcohol use disorder by affecting synaptic plasticity. | Zhu S et al. | β | 2022 | β |
| Principal Component Analysis Reduces Collider Bias in Polygenic Score Effect Size Estimation. | Thomas NS et al. | β | 2022 | β |
| A latent class analysis of alcohol and posttraumatic stress symptoms among offspring of parents with and without alcohol use disorder. | Bender AK et al. | β | 2021 | β |
| Genetic Basis of Dual Diagnosis: A Review of Genome-Wide Association Studies (GWAS) Focusing on Patients with Mood or Anxiety Disorders and Co-Occurring Alcohol-Use Disorders. | Stoychev K et al. | β | 2021 | β |
| Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. | Lai D et al. | β | 2021 | β |
| Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. | Sherva R et al. | β | 2021 | β |
| Genomic and Personalized Medicine Approaches for Substance Use Disorders (SUDs) Looking at Genome-Wide Association Studies. | Cozzoli D et al. | β | 2021 | β |
| Mapping Pathways by Which Genetic Risk Influences Adolescent Externalizing Behavior: The Interplay Between Externalizing Polygenic Risk Scores, Parental Knowledge, and Peer Substance Use. | Kuo SI et al. | β | 2021 | β |
| Opioid Misuse among Smokers with Chronic Pain: Relations with Substance Use and Mental Health. | Zvolensky MJ et al. | β | 2021 | β |
| Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk. | Cho SB et al. | β | 2021 | β |
| Identification of Functional Genetic Variants Associated With Alcohol Dependence and Related Phenotypes Using a High-Throughput Assay. | Thapa KS et al. | β | 2020 | β |
| Trauma Exposure and Post-Traumatic Stress Disorder Among Youth in a High-Risk Family Study: Associations with Maternal and Paternal Alcohol Use Disorder. | Bender AK et al. | β | 2020 | β |
| Development of Alcohol Use Disorder as a Function of Age, Severity, and Comorbidity with Externalizing and Internalizing Disorders in a Young Adult Cohort. | Nurnberger JI et al. | β | 2019 | β |
| Exploring the relationship between polygenic risk for cannabis use, peer cannabis use and the longitudinal course of cannabis involvement. | Johnson EC et al. | β | 2019 | β |
| Genetic determinants of beverage consumption: Implications for nutrition and health. | Cornelis MC | β | 2019 | β |
| Genetics of alcohol use disorder: a review. | Deak JD et al. | β | 2019 | β |
| Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. | Lai D et al. | β | 2019 | β |
| Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. | Wetherill L et al. | β | 2019 | β |
| Positive and negative reinforcement are differentially associated with alcohol consumption as a function of alcohol dependence. | Cho SB et al. | β | 2019 | β |
| Qualitative vs. Quantitative Methods in Psychiatric Research: Updated. | Srivastava AB et al. | β | 2019 | β |
| Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families. | McCutcheon VV et al. | β | 2018 | β |
| Defining the phenotype of young adults with family histories of alcohol and other substance use disorders: Studies from the family health patterns project. | Acheson A et al. | β | 2018 | β |
| GABA<sub>A</sub> receptor polymorphisms in alcohol use disorder in the GWAS era. | Koulentaki M et al. | β | 2018 | β |
| GABRA2, alcohol, and illicit drug use: An event-level model of genetic risk for polysubstance use. | Mallard TT et al. | β | 2018 | β |
| The Role of Cell Adhesion Molecule Genes Regulating Neuroplasticity in Addiction. | Muskiewicz DE et al. | β | 2018 | β |
| Alcohol Consumption and Long-Term Labor Market Outcomes. | BΓΆckerman P et al. | β | 2017 | β |
| An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry. | Meyers JL et al. | β | 2017 | β |
| A preclinical model for identifying rats at risk of alcohol use disorder. | Jadhav KS et al. | β | 2017 | β |
| Associations Between Genomic Variants in Alcohol Dehydrogenase Genes and Alcohol Symptomatology in American Indians and European Americans: Distinctions and Convergence. | Peng Q et al. | β | 2017 | β |
| Commentary on McCutcheon et al. (2017): Familial transmission of abstinent remission and social cognition. | Hill SY | β | 2017 | β |
| Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study. | Bucholz KK et al. | β | 2017 | β |
| Contributions of Genes and Environment to Developmental Change in Alcohol Use. | Long EC et al. | β | 2017 | β |
| GABA<sub>A</sub> receptor subtype involvement in addictive behaviour. | Stephens DN et al. | β | 2017 | β |
| Genetic studies of alcohol dependence in the context of the addiction cycle. | Reilly MT et al. | β | 2017 | β |
| Rat animal models for screening medications to treat alcohol use disorders. | Bell RL et al. | β | 2017 | β |
| Review: Genetic and environmental risk factors for alcohol use disorders in American Indians and Alaskan Natives. | Enoch MA et al. | β | 2017 | β |
| The association between personality disorders with alcohol use and misuse: A population-based twin study. | Long EC et al. | β | 2017 | β |
| The genetics of alcohol dependence and alcohol-related liver disease. | Stickel F et al. | β | 2017 | β |
| Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations. | Mathies LD et al. | β | 2017 | β |
| Alcohol-Induced Stimulation Mediates the Effect of a GABRA2 SNP on Alcohol Self-Administrated among Alcohol-Dependent Individuals. | Boyd SJ et al. | β | 2016 | β |
| Analysis of Rare Variants in the Alcohol Dependence Candidate Gene GATA4. | Degenhardt F et al. | β | 2016 | β |
| Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement. | Carey CE et al. | β | 2016 | β |
| Association Study of Gene Polymorphisms in GABA, Serotonin, Dopamine, and Alcohol Metabolism Pathways with Alcohol Dependence in Taiwanese Han Men. | Wu LS et al. | β | 2016 | β |
| Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addiction. | Orsini CA et al. | β | 2016 | β |
| Devil in disguise: Does drinking lead to a disability pension? | BΓΆckerman P et al. | β | 2016 | β |
| Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. | Bell RL et al. | β | 2016 | β |
| Modeling Multiple Responses via Bootstrapping Margins with an Application to Genetic Association Testing. | Zhao J et al. | β | 2016 | β |
| Overview of the Genetics of Alcohol Use Disorder. | Tawa EA et al. | β | 2016 | β |
| Protein Kinase C Epsilon Activity in the Nucleus Accumbens and Central Nucleus of the Amygdala Mediates Binge Alcohol Consumption. | Cozzoli DK et al. | β | 2016 | β |
| ACN9 and alcohol dependence: family-based association analysis in multiplex alcohol dependence families. | Hill SY et al. | β | 2015 | β |
| Association of GABAA receptor Ξ±2 subunit gene (GABRA2) with alcohol dependence-related aggressive behavior. | Strac DS et al. | β | 2015 | β |
| Candidate gene-environment interaction research: reflections and recommendations. | Dick DM et al. | β | 2015 | β |
| Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms. | Manzardo AM et al. | β | 2015 | β |
| Deficient Event-Related Theta Oscillations in Individuals at Risk for Alcoholism: A Study of Reward Processing and Impulsivity Features. | Kamarajan C et al. | β | 2015 | β |
| Further Analyses of Genetic Association Between GRM8 and Alcohol Dependence Symptoms Among Young Adults. | Long EC et al. | β | 2015 | β |
| Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample. | Aliev F et al. | β | 2015 | β |
| Integrative epigenetic profiling analysis identifies DNA methylation changes associated with chronic alcohol consumption. | Weng JT et al. | β | 2015 | β |
| Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. | Carey CE et al. | β | 2015 | β |
| Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task. | Kamarajan C et al. | β | 2015 | β |
| Serotonin and Dopamine Candidate Gene Variants and Alcohol- and Non-Alcohol-Related Aggression. | Preuss UW et al. | β | 2015 | β |
| Val158Met COMT polymorphism and risk of aggression in alcohol dependence. | Soyka M et al. | β | 2015 | β |
| A GABRA2 variant is associated with increased stimulation and 'high' following alcohol administration. | Arias AJ et al. | β | 2014 | β |
| Alcohol Exposure <i>In Utero</i> and Child Academic Achievement. | von Hinke Kessler Scholder S et al. | β | 2014 | β |
| Anomalous temporoparietal activity in individuals with a family history of alcoholism: studies from the Oklahoma Family Health Patterns Project. | Acheson A et al. | β | 2014 | β |
| Assessment of whole brain white matter integrity in youths and young adults with a family history of substance-use disorders. | Acheson A et al. | β | 2014 | β |
| Association between copy number variation losses and alcohol dependence across African American and European American ethnic groups. | Ulloa AE et al. | β | 2014 | β |
| Association of gamma-aminobutyric acid A receptor Ξ±2 gene (GABRA2) with alcohol use disorder. | Li D et al. | β | 2014 | β |
| Association of the CHRNA4 neuronal nicotinic receptor subunit gene with frequency of binge drinking in young adults. | Coon H et al. | β | 2014 | β |
| Cognitive mediators and disparities in the relation between teen depressiveness and smoking. | Mistry R et al. | β | 2014 | β |
| Combining diffusion tensor imaging and magnetic resonance spectroscopy to study reduced frontal white matter integrity in youths with family histories of substance use disorders. | Acheson A et al. | β | 2014 | β |
| Delay discounting differentiates pre-adolescents at high and low risk for substance use disorders based on family history. | Dougherty DM et al. | β | 2014 | β |
| DSM-5 cannabis use disorder: a phenotypic and genomic perspective. | Agrawal A et al. | β | 2014 | β |
| Genetics and genomics of alcohol sensitivity. | Morozova TV et al. | β | 2014 | β |
| Genetics of alcohol dependence: a review of clinical studies. | Samochowiec J et al. | β | 2014 | β |
| Genetics of alcoholism. | Edenberg HJ et al. | β | 2014 | β |
| Genetics of alcoholism. | Iyer-Eimerbrink PA et al. | β | 2014 | β |
| Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. | Kapoor M et al. | β | 2014 | β |
| Identifying Genetic Variants for Addiction via Propensity Score Adjusted Generalized Kendall's Tau. | Jiang Y et al. | β | 2014 | β |
| Initial subjective reward: single-exposure conditioned place preference to alcohol in mice. | Grisel JE et al. | β | 2014 | β |
| Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants. | Wang S et al. | β | 2014 | β |
| Moderators of the association between peer and target adolescent substance use. | Marschall-LΓ©vesque S et al. | β | 2014 | β |
| Nonhuman primate models of neuropsychiatric disorders: influences of early rearing, genetics, and epigenetics. | Dettmer AM et al. | β | 2014 | β |
| Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders. | Kos MZ et al. | β | 2014 | β |
| Perspectives on the neuroscience of alcohol from the National Institute on Alcohol Abuse and Alcoholism. | Reilly MT et al. | β | 2014 | β |
| Reduced expression of Ξ±-synuclein in alcoholic brain: influence of SNCA-Rep1 genotype. | Janeczek P et al. | β | 2014 | β |
| A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. | Wang JC et al. | β | 2013 | β |
| Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. | Kos MZ et al. | β | 2013 | β |
| Common variants in HLA-DRA gene are associated with alcohol dependence in two Caucasian samples. | Pan Y et al. | β | 2013 | β |
| Family-based association analysis of alcohol dependence implicates KIAA0040 on Chromosome 1q in multiplex alcohol dependence families. | Hill SY et al. | β | 2013 | β |
| GABRA2 markers moderate the subjective effects of alcohol. | Uhart M et al. | β | 2013 | β |
| Genetic association test for multiple traits at gene level. | Guo X et al. | β | 2013 | β |
| Genetic influences on the development of alcoholism. | Enoch MA | β | 2013 | β |
| Genetic instrumental variable studies of effects of prenatal risk factors. | Wehby GL et al. | β | 2013 | β |
| Genetics and alcoholism. | Edenberg HJ et al. | β | 2013 | β |
| Genetic sensitivity to peer behaviors: 5HTTLPR, smoking, and alcohol consumption. | Daw J et al. | β | 2013 | β |
| Genetics of alcohol dependence and social work research: do they mix? | Hesselbrock MN et al. | β | 2013 | β |
| How phenotype and developmental stage affect the genes we find: GABRA2 and impulsivity. | Dick DM et al. | β | 2013 | β |
| Implications of genome wide association studies for addiction: are our a priori assumptions all wrong? | Hall FS et al. | β | 2013 | β |
| Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. | Han S et al. | β | 2013 | β |
| NCK2 is significantly associated with opiates addiction in African-origin men. | Liu Z et al. | β | 2013 | β |
| NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. | Zuo L et al. | β | 2013 | β |
| PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort. | Preuss UW et al. | β | 2013 | β |
| Peter Riederer "70th birthday" neurobiological foundations of modern addiction treatment. | Jacob C | β | 2013 | β |
| Polymorphisms of genes in neurotransmitter systems were associated with alcohol use disorders in a Tibetan population. | Xu Y et al. | β | 2013 | β |
| Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent. | Zuo L et al. | β | 2013 | β |
| The genetics of alcohol dependence. | Rietschel M et al. | β | 2013 | β |
| The role of Ξ±-synuclein in the pathophysiology of alcoholism. | Janeczek P et al. | β | 2013 | β |
| A common genetic network underlies substance use disorders and disruptive or externalizing disorders. | Arcos-Burgos M et al. | β | 2012 | β |
| ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry. | Bierut LJ et al. | β | 2012 | β |
| ADH4 intronic variations are associated with alcohol dependence: results from an Italian case-control association study. | Turchi C et al. | β | 2012 | β |
| ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. | Chen XD et al. | β | 2012 | β |
| ASTN1 and alcohol dependence: family-based association analysis in multiplex alcohol dependence families. | Hill SY et al. | β | 2012 | β |
| Bridging Animal and Human Models: Translating From (and to) Animal Genetics. | Barkley-Levenson AM et al. | β | 2012 | β |
| Chronic alcohol exposure alters gene expression in HepG2 cells. | Pochareddy S et al. | β | 2012 | β |
| Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. | Lin P et al. | β | 2012 | β |
| Family-based genome-wide association study of frontal ΞΈ oscillations identifies potassium channel gene KCNJ6. | Kang SJ et al. | β | 2012 | β |
| Frontoparietal connectivity in substance-naΓ―ve youth with and without a family history of alcoholism. | Wetherill RR et al. | β | 2012 | β |
| GABA-A receptor genes do not play a role in genetics of Lesch's typology in Caucasian subjects. | Grzywacz A et al. | β | 2012 | β |
| GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans. | Ittiwut C et al. | β | 2012 | β |
| Genetic determinants of alcoholic liver disease. | Stickel F et al. | β | 2012 | β |
| Genetic dissection of acute ethanol responsive gene networks in prefrontal cortex: functional and mechanistic implications. | Wolen AR et al. | β | 2012 | β |
| Genetics of GABAergic signaling in nicotine and alcohol dependence. | Cui WY et al. | β | 2012 | β |
| Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction. | Wallis D et al. | β | 2012 | β |
| Large scale association analysis for drug addiction: results from SNP to gene. | Guo X et al. | β | 2012 | β |
| Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans. | Han S et al. | β | 2012 | β |
| Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study. | Zhao Z et al. | β | 2012 | β |
| Nonparametric Covariate-Adjusted Association Tests Based on the Generalized Kendall's Tau(). | Zhu W et al. | β | 2012 | β |
| Recent advances in the genetic epidemiology and molecular genetics of substance use disorders. | Kendler KS et al. | β | 2012 | β |
| The genetics of alcohol dependence: advancing towards systems-based approaches. | Palmer RH et al. | β | 2012 | β |
| The genetics of substance dependence. | Wang JC et al. | β | 2012 | β |
| The interpretability of family history reports of alcoholism in general community samples: findings in a midwestern U.S. twin birth cohort. | Waldron M et al. | β | 2012 | β |
| Adults with a family history of alcohol related problems are more impulsive on measures of response initiation and response inhibition. | Acheson A et al. | β | 2011 | β |
| An Interdisciplinary Approach to Studying Gene-Environment Interactions: From Twin Studies to Gene Identification and Back. | Dick DM | β | 2011 | β |
| An overview of the genetic susceptibility to alcoholism. | Buscemi L et al. | β | 2011 | β |
| A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. | Heath AC et al. | β | 2011 | β |
| Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study. | Preuss UW et al. | β | 2011 | β |
| Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a Native American community sample. | Gizer IR et al. | β | 2011 | β |
| Association of CHRM2 polymorphisms with severity of alcohol dependence. | Jung MH et al. | β | 2011 | β |
| Balancing environmental and genetic factors for alcoholism in the black community: implications for social work practice. | Snell CL et al. | β | 2011 | β |
| Brief interventions for alcohol misuse. | Botelho R et al. | β | 2011 | β |
| Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol. | McCutcheon VV et al. | β | 2011 | β |
| Genetics of alcohol dependence. | Kimura M et al. | β | 2011 | β |
| Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men. | Baik I et al. | β | 2011 | β |
| Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. | Zlojutro M et al. | β | 2011 | β |
| Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations. | Liu J et al. | β | 2011 | β |
| Interaction between the DRD4 VNTR polymorphism and proximal and distal environments in alcohol dependence during emerging and young adulthood. | Park A et al. | β | 2011 | β |
| Linkage scan of alcohol dependence in the UCSF Family Alcoholism Study. | Gizer IR et al. | β | 2011 | β |
| Overexpression of 5-HT(1B) mRNA in nucleus accumbens shell projection neurons differentially affects microarchitecture of initiation andΒ maintenance of ethanol consumption. | Furay AR et al. | β | 2011 | β |
| Role of GABRA2 in moderating subjective responses to alcohol. | Roh S et al. | β | 2011 | β |
| Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics. | Jin Z et al. | β | 2011 | β |
| Statistical Analysis in Genetic Studies of Mental Illnesses. | Zhang H | β | 2011 | β |
| The AVPR1A gene and substance use disorders: association, replication, and functional evidence. | Maher BS et al. | β | 2011 | β |
| The influence of gene-environment interactions on alcohol consumption and alcohol use disorders: a comprehensive review. | Young-Wolff KC et al. | β | 2011 | β |
| The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women. | Chen X et al. | β | 2011 | β |
| A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models. | Ehlers CL et al. | β | 2010 | β |
| A genome-wide association study of alcohol dependence. | Bierut LJ et al. | β | 2010 | β |
| An Association Test for Multiple Traits Based on the Generalized Kendall's Tau. | Zhang H et al. | β | 2010 | β |
| A new definition of early age at onset in alcohol dependence. | Le Strat Y et al. | β | 2010 | β |
| ChIP-chip analysis of neurexins and other candidate genes for addiction and neuropsychiatric disorders. | Pedrosa E et al. | β | 2010 | β |
| Delineating the psychic structure of substance abuse and addictions: should anxiety, mood and impulse-control dysregulation be included? | Pani PP et al. | β | 2010 | β |
| EEG alpha phenotypes: linkage analyses and relation to alcohol dependence in an American Indian community study. | Ehlers CL et al. | β | 2010 | β |
| Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. | Dick DM et al. | β | 2010 | β |
| Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques. | Lindell SG et al. | β | 2010 | β |
| GABRA2 and alcohol use disorders: no evidence of an association in an Italian case-control study. | Onori N et al. | β | 2010 | β |
| GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence. | Xuei X et al. | β | 2010 | β |
| Genetic research: who is at risk for alcoholism. | Foroud T et al. | β | 2010 | β |
| Genetics of addictions. | Hartz SM et al. | β | 2010 | β |
| Genetics of addictions. | Hartz SM et al. | β | 2010 | β |
| Genome-wide association study of alcohol dependence implicates a region on chromosome 11. | Edenberg HJ et al. | β | 2010 | β |
| Heritability of MMPI-2 scales in the UCSF family alcoholism study. | Gizer IR et al. | β | 2010 | β |
| Identification of a FOXA-dependent enhancer of human alcohol dehydrogenase 4 (ADH4). | Pochareddy S et al. | β | 2010 | β |
| Linkage analyses of cannabis dependence, craving, and withdrawal in the San Francisco family study. | Ehlers CL et al. | β | 2010 | β |
| Linkage analysis of alcohol dependence symptoms in the community. | Hansell NK et al. | β | 2010 | β |
| Neural circuitry associated with risk for alcohol use disorders. | Tessner KD et al. | β | 2010 | β |
| Neural markers of genetic vulnerability to drug addiction. | MΓΌller DJ et al. | β | 2010 | β |
| Neural plasticity, human genetics, and risk for alcohol dependence. | Hill SY | β | 2010 | β |
| Obesity, smoking, and frontal brain dysfunction. | Bauer L et al. | β | 2010 | β |
| Predicting sensation seeking from dopamine genes. A candidate-system approach. | Derringer J et al. | β | 2010 | β |
| Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence. | Chen AC et al. | β | 2010 | β |
| The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence. | Enoch MA et al. | β | 2010 | β |
| ADH single nucleotide polymorphism associations with alcohol metabolism in vivo. | Birley AJ et al. | β | 2009 | β |
| Alcohol consumption indices of genetic risk for alcohol dependence. | Grant JD et al. | β | 2009 | β |
| A non-synonymous variant in ADH1B is strongly associated with prenatal alcohol use in a European sample of pregnant women. | Zuccolo L et al. | β | 2009 | β |
| Association of ADH1B and ALDH2 gene polymorphisms with alcohol dependence: a pilot study from India. | Vaswani M et al. | β | 2009 | β |
| Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. | Chen AC et al. | β | 2009 | β |
| Associations among GABRG1, level of response to alcohol, and drinking behaviors. | Ray LA et al. | β | 2009 | β |
| Associations and interactions between SNPs in the alcohol metabolizing genes and alcoholism phenotypes in European Americans. | Sherva R et al. | β | 2009 | β |
| Can we identify genes for alcohol consumption in samples ascertained for heterogeneous purposes? | Hansell NK et al. | β | 2009 | β |
| Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10. | Gelernter J et al. | β | 2009 | β |
| Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder. | Cohen-Woods S et al. | β | 2009 | β |
| Developing a quantitative measure of alcohol consumption for genomic studies on prospective cohorts. | Agrawal A et al. | β | 2009 | β |
| Differential activation of the anterior cingulate cortex and caudate nucleus during a gambling simulation in persons with a family history of alcoholism: studies from the Oklahoma Family Health Patterns Project. | Acheson A et al. | β | 2009 | β |
| Dimensionality of lifetime alcohol abuse, dependence and binge drinking. | Hasin DS et al. | β | 2009 | β |
| Dopamine D4 receptor gene exon III polymorphism associated with binge drinking attitudinal phenotype. | Vaughn MG et al. | β | 2009 | β |
| ERGR: An ethanol-related gene resource. | Guo AY et al. | β | 2009 | β |
| GABRG1 and GABRA2 as independent predictors for alcoholism in two populations. | Enoch MA et al. | β | 2009 | β |
| [Genetic factors of alcohol-dependence]. | Pinto E et al. | β | 2009 | β |
| Genetics of alcohol dependence. | Gelernter J et al. | β | 2009 | β |
| Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. | Wang JC et al. | β | 2009 | β |
| New insights into the genetics of addiction. | Li MD et al. | β | 2009 | β |
| Polymorphisms in the promoter region of the human class II alcohol dehydrogenase (ADH4) gene affect both transcriptional activity and ethanol metabolism in Japanese subjects. | Kimura Y et al. | β | 2009 | β |
| Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant. | Li H et al. | β | 2009 | β |
| The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. | Kumar S et al. | β | 2009 | β |
| Addiction science and its genetics. | Ball D | β | 2008 | β |
| A genomic imprinting test for ordinal traits in pedigree data. | Feng R et al. | β | 2008 | β |
| A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs. | Ghosh S et al. | β | 2008 | β |
| Approach to the genetics of alcoholism: a review based on pathophysiology. | KΓΆhnke MD | β | 2008 | β |
| A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence. | Edenberg HJ et al. | β | 2008 | β |
| A score test for linkage analysis of ordinal traits based on IBD sharing. | Feng R et al. | β | 2008 | β |
| Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence. | Xuei X et al. | β | 2008 | β |
| A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9. | Dick DM et al. | β | 2008 | β |
| Craving for alcohol and food during treatment for alcohol dependence: modulation by T allele of 1519T>C GABAAalpha6. | Han DH et al. | β | 2008 | β |
| Effects of GABRA2 variation on physiological, psychomotor and subjective responses in the alcohol challenge twin study. | Lind PA et al. | β | 2008 | β |
| Ethnic related selection for an ADH Class I variant within East Asia. | Li H et al. | β | 2008 | β |
| Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data. | Kim Y et al. | β | 2008 | β |
| GABA-A2 receptor subunit gene (GABRA2) polymorphisms and risk for alcohol dependence. | Soyka M et al. | β | 2008 | β |
| GABA(A) receptors and alcohol. | Lobo IA et al. | β | 2008 | β |
| Genetic approaches to addiction: genes and alcohol. | Ducci F et al. | β | 2008 | β |
| Genetics of nicotine dependence and pharmacotherapy. | Lessov-Schlaggar CN et al. | β | 2008 | β |
| Genome-wide linkage scan for nicotine dependence in European Americans and its converging results with African Americans in the Mid-South Tobacco Family sample. | Li MD et al. | β | 2008 | β |
| Genotype patterns that contribute to increased risk for or protection from developing heroin addiction. | Nielsen DA et al. | β | 2008 | β |
| HPA-axis activity in alcoholism: examples for a gene-environment interaction. | Clarke TK et al. | β | 2008 | β |
| Human gamma-aminobutyric acid A receptor alpha2 gene moderates the acute effects of alcohol and brain mRNA expression. | Haughey HM et al. | β | 2008 | β |
| Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4. | Ittiwut C et al. | β | 2008 | β |
| Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. | Agrawal A et al. | β | 2008 | β |
| Long-term stability and heritability of telephone interview measures of alcohol consumption and dependence. | Hansell NK et al. | β | 2008 | β |
| Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene. | Covault J et al. | β | 2008 | β |
| Molecular genetics of alcohol dependence and related endophenotypes. | Strat YL et al. | β | 2008 | β |
| Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence. | Wetherill L et al. | β | 2008 | β |
| Ordered subsets linkage analysis of antisocial behavior in substance use disorder among participants in the Collaborative Study on the Genetics of Alcoholism. | Jacobson KC et al. | β | 2008 | β |
| Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism. | Le-Niculescu H et al. | β | 2008 | β |
| [Problems occurring in the application of cytogenetic biomarkers for alcoholics with and without malignant diseases]. | Gundy S et al. | β | 2008 | β |
| Review. Genetics of addictions: strategies for addressing heterogeneity and polygenicity of substance use disorders. | Wong CC et al. | β | 2008 | β |
| The role of GABA(A) receptors in the development of alcoholism. | Enoch MA | β | 2008 | β |
| The role of GABRA2 in alcohol dependence, smoking, and illicit drug use in an Australian population sample. | Lind PA et al. | β | 2008 | β |
| The tachykinin receptor 3 is associated with alcohol and cocaine dependence. | Foroud T et al. | β | 2008 | β |
| Under the influence of genetics: how transdisciplinarity leads us to rethink social pathways to illness. | Pescosolido BA et al. | β | 2008 | β |
| Variants in nicotinic receptors and risk for nicotine dependence. | Bierut LJ et al. | β | 2008 | β |
| A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: evidence for linkage on chromosomes 3 and 9. | Hopfer CJ et al. | β | 2007 | β |
| Association analyses of the serotonin transporter gene with lifetime depression and alcohol dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. | Dick DM et al. | β | 2007 | β |
| Association of alcohol craving with alpha-synuclein (SNCA). | Foroud T et al. | β | 2007 | β |
| Attention-deficit/hyperactivity disorder and comorbid disruptive behavior disorders: evidence of pleiotropy and new susceptibility loci. | Jain M et al. | β | 2007 | β |
| Between- and within-family association test of the dopamine receptor D2 TaqIA polymorphism and alcohol abuse and dependence in a general population sample of adults. | Haberstick BC et al. | β | 2007 | β |
| Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity. | Lipsky RH et al. | β | 2007 | β |
| Candidate genes, pathways and mechanisms for alcoholism: an expanded convergent functional genomics approach. | Rodd ZA et al. | β | 2007 | β |
| Evidence of positive selection on a class I ADH locus. | Han Y et al. | β | 2007 | β |
| Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. | Wang JC et al. | β | 2007 | β |
| Genomewide suggestive linkage of opioid dependence to chromosome 14q. | Lachman HM et al. | β | 2007 | β |
| Impact of the alcohol-dehydrogenase (ADH) 1C and ADH1B polymorphisms on drinking behavior in nonalcoholic Japanese. | Matsuo K et al. | β | 2007 | β |
| Involvement of cannabinoid CB2 receptor in alcohol preference in mice and alcoholism in humans. | Ishiguro H et al. | β | 2007 | β |
| Lack of association of alcohol dependence and habitual smoking with catechol-O-methyltransferase. | Foroud T et al. | β | 2007 | β |
| Linkage disequilibrium and association analysis of alpha-synuclein and alcohol and drug dependence in two American Indian populations. | Clarimon J et al. | β | 2007 | β |
| Nucleotide sequence variation within the human tyrosine kinase B neurotrophin receptor gene: association with antisocial alcohol dependence. | Xu K et al. | β | 2007 | β |
| Opioid dependence and addiction during opioid treatment of chronic pain. | Ballantyne JC et al. | β | 2007 | β |
| Single nucleotide polymorphisms of the ALDH2 gene in six Indian populations. | Bhaskar LV et al. | β | 2007 | β |
| The opioid system in alcohol and drug dependence: family-based association study. | Xuei X et al. | β | 2007 | β |
| The role of the GABRA2 polymorphism in multiplex alcohol dependence families with minimal comorbidity: within-family association and linkage analyses. | Matthews AG et al. | β | 2007 | β |
| Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. | Le-Niculescu H et al. | β | 2007 | β |
| Variation in GABRA2 predicts drinking behavior in project MATCH subjects. | Bauer LO et al. | β | 2007 | β |
| A cholinergic receptor gene (CHRM2) affects event-related oscillations. | Jones KA et al. | β | 2006 | β |
| ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies. | Luo X et al. | β | 2006 | β |
| Alcoholism: Study boosts evidence on linkage regions associated with alcoholism. | Hopfer C | β | 2006 | β |
| Association between GABRA1 and drinking behaviors in the collaborative study on the genetics of alcoholism sample. | Dick DM et al. | β | 2006 | β |
| Association of a D2S2944 allele with depression specifically among those with substance abuse or antisocial personality. | Langbehn DR et al. | β | 2006 | β |
| Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample. | Agrawal A et al. | β | 2006 | β |
| Association of the kappa-opioid system with alcohol dependence. | Xuei X et al. | β | 2006 | β |
| Challenges in genetic studies of the etiology of substance use and substance use disorders: introduction to the special issue. | Prescott CA et al. | β | 2006 | β |
| Cognitive traits link to human chromosomal regions. | Buyske S et al. | β | 2006 | β |
| Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis. | Fehr C et al. | β | 2006 | β |
| Different effects of stress on alcohol drinking behaviour in male and female mice selectively bred for high alcohol preference. | Chester JA et al. | β | 2006 | β |
| Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. | Luo X et al. | β | 2006 | β |
| Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. | Dick DM et al. | β | 2006 | β |
| Family-based association tests for ordinal traits adjusting for covariates. | Wang X et al. | β | 2006 | β |
| Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. | Hinrichs AL et al. | β | 2006 | β |
| GABA(A) receptor subtypes as targets for neuropsychiatric drug development. | Korpi ER et al. | β | 2006 | β |
| Genetics and alcoholism: how close are we to potential clinical applications? | Quickfall J et al. | β | 2006 | β |
| Genomic screen for loci associated with tobacco usage in Mission Indians. | Ehlers CL et al. | β | 2006 | β |
| Identification of susceptibility loci for alcohol-related traits in the Irish Affected Sib Pair Study of Alcohol Dependence. | Kuo PH et al. | β | 2006 | β |
| Ionotropic glutamate receptor gene GRIK3 SER310ALA functional polymorphism is related to delirium tremens in alcoholics. | Preuss UW et al. | β | 2006 | β |
| Linkage analyses of IQ in the collaborative study on the genetics of alcoholism (COGA) sample. | Dick DM et al. | β | 2006 | β |
| Linkage disequilibrium, haplotype and association studies of a chromosome 4 GABA receptor gene cluster: candidate gene variants for addictions. | Drgon T et al. | β | 2006 | β |
| Molecular genetics of addiction vulnerability. | Uhl GR | β | 2006 | β |
| New findings on the genetic influences on alcohol use and dependence. | Higuchi S et al. | β | 2006 | β |
| NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice. | Ishiguro H et al. | β | 2006 | β |
| Peripheral blood alpha-synuclein mRNA levels are elevated in cynomolgus monkeys that chronically self-administer ethanol. | Walker SJ et al. | β | 2006 | β |
| Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism. | Johnson C et al. | β | 2006 | β |
| The genetics of alcoholism: identifying specific genes through family studies. | Edenberg HJ et al. | β | 2006 | β |
| A genome-wide linkage analysis of alcoholism on microsatellite and single-nucleotide polymorphism data, using alcohol dependence phenotypes and electroencephalogram measures. | Zhang C et al. | β | 2005 | β |
| A genome-wide scanning and fine mapping study of COGA data. | Yang HC et al. | β | 2005 | β |
| Alcohol and gene expression in the central nervous system. | Worst TJ et al. | β | 2005 | β |
| Alcohol and gene interactions. | Whitfield JB | β | 2005 | β |
| Alcoholism and related traits: a summary of Group 13 contributions. | Rice JP et al. | β | 2005 | β |
| [Alpha-thalassemias and bipolar disorders: a genetic link?]. | Damsa C et al. | β | 2005 | β |
| A new method of linkage analysis using LOD scores for quantitative traits supports linkage of monoamine oxidase activity to D17S250 in the Collaborative Study on the Genetics of Alcoholism pedigrees. | Curtis D et al. | β | 2005 | β |
| Application of the propensity score in a covariate-based linkage analysis of the Collaborative Study on the Genetics of Alcoholism. | Doan BQ et al. | β | 2005 | β |
| Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population. | Lappalainen J et al. | β | 2005 | β |
| A study of genetic association with electrophysiological measures related to alcoholism: GAW14 data. | Yuan A et al. | β | 2005 | β |
| Bivariate genome scans incorporating factor and principal component analyses to identify common genetic components of alcoholism, event-related potential, and electroencephalogram phenotypes. | Lin JP et al. | β | 2005 | β |
| CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study. | Luo X et al. | β | 2005 | β |
| Combining research approaches to advance our understanding of drug addiction. | van den Bree MB | β | 2005 | β |
| Comorbid alcohol and nicotine dependence: from the biomolecular basis to clinical consequences. | Ait-Daoud N et al. | β | 2005 | β |
| Comparison of genotype- and haplotype-based approaches for fine-mapping of alcohol dependence using COGA data. | Pinnaduwage D et al. | β | 2005 | β |
| Comparison of linkage and association strategies for quantitative traits using the COGA dataset. | McQueen MB et al. | β | 2005 | β |
| Comparison of single-nucleotide polymorphisms and microsatellites in detecting quantitative trait loci for alcoholism: the Collaborative Study on the Genetics of Alcoholism. | Kim H et al. | β | 2005 | β |
| Conceptual framework for the etiology of alcoholism: a "kindling"/stress hypothesis. | Breese GR et al. | β | 2005 | β |
| Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14. | Edenberg HJ et al. | β | 2005 | β |
| Ebrii gignunt ebrios--One drunkard begets another: the genetics of alcohol dependence. | Ball D | β | 2005 | β |
| EEG spectral changes in treatment-naive, actively drinking alcoholics. | Fein G et al. | β | 2005 | β |
| Evaluation of linkage disequilibrium and its effect on non-parametric multipoint linkage analysis using two high density single-nucleotide polymorphism mapping panels. | Murray SS | β | 2005 | β |
| GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride. | Pierucci-Lagha A et al. | β | 2005 | β |
| Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students. | Wall TL et al. | β | 2005 | β |
| Genetic influences in emotional dysfunction and alcoholism-related brain damage. | Oscar-Berman M et al. | β | 2005 | β |
| Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2. | Guerrini I et al. | β | 2005 | β |
| Genetic time-series analysis identifies a major QTL for in vivo alcohol metabolism not predicted by in vitro studies of structural protein polymorphism at the ADH1B or ADH1C loci. | Birley AJ et al. | β | 2005 | β |
| Genome-wide linkage analysis for alcohol dependence: a comparison between single-nucleotide polymorphism and microsatellite marker assays. | Ma Q et al. | β | 2005 | β |
| Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia. | Gelernter J et al. | β | 2005 | β |
| Genomic screening in family-based association testing. | Murphy A et al. | β | 2005 | β |
| Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium. | Duggal P et al. | β | 2005 | β |
| Joint analysis of the NACP-REP1 marker within the alpha synuclein gene concludes association with alcohol dependence. | BΓΆnsch D et al. | β | 2005 | β |
| Linkage analysis and association analysis in the presence of linkage using age at onset of COGA alcoholism data. | Zhong X et al. | β | 2005 | β |
| Linkage analysis of alcohol dependence using both affected and discordant sib pairs. | Shih PY et al. | β | 2005 | β |
| Linkage analysis of alcoholism-related electrophysiological phenotypes: genome scans with microsatellites compared to single-nucleotide polymorphisms. | Bautista JF et al. | β | 2005 | β |
| Linkage analysis of complex diseases using microsatellites and single-nucleotide polymorphisms: application to alcoholism. | Nsengimana J et al. | β | 2005 | β |
| Microsatellites versus single-nucleotide polymorphisms in linkage analysis for quantitative and qualitative measures. | Dunn G et al. | β | 2005 | β |
| Multilocus and interaction-based genome scan for alcoholism risk factors in Caucasian Americans: the COGA study. | Williams AH et al. | β | 2005 | β |
| Natural haplotypes in the regulatory sequences affect human alcohol dehydrogenase 1C (ADH1C) gene expression. | Chen HJ et al. | β | 2005 | β |
| No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample. | Dick DM et al. | β | 2005 | β |
| Optimizing the evidence for linkage by permuting marker order. | Jun G et al. | β | 2005 | β |
| Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments. | Kreek MJ et al. | β | 2005 | β |
| Scanning of genetic effects of alcohol metabolism gene (ADH1B and ADH1C) polymorphisms on the risk of alcoholism. | Choi IG et al. | β | 2005 | β |
| Support for previously identified alcoholism susceptibility Loci in a cohort selected for smoking behavior. | Wilhelmsen KC et al. | β | 2005 | β |
| Surrogate phenotype definition for alcohol use disorders: a genome-wide search for linkage and association. | Rosenberger A et al. | β | 2005 | β |
| The contribution of genetics to addiction therapy approaches. | Edenberg HJ et al. | β | 2005 | β |
| The development of alcohol use disorders. | Sher KJ et al. | β | 2005 | β |
| The genetics of addictions: uncovering the genes. | Goldman D et al. | β | 2005 | β |
| The utility of neurophysiological markers in the study of alcoholism. | Porjesz B et al. | β | 2005 | β |
| Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. | Worst TJ et al. | β | 2005 | β |
| A genome-wide screen for genes influencing conduct disorder. | Dick DM et al. | β | 2004 | β |
| A genome wide search for alcoholism susceptibility genes. | Hill SY et al. | β | 2004 | β |
| Alcoholism: genes and mechanisms. | Oroszi G et al. | β | 2004 | β |
| Alcohol use disorders and mood disorders: a National Institute on Alcohol Abuse and Alcoholism perspective. | Li TK et al. | β | 2004 | β |
| Allelic and haplotypic association of GABRA2 with alcohol dependence. | Covault J et al. | β | 2004 | β |
| Association of GABRG3 with alcohol dependence. | Dick DM et al. | β | 2004 | β |
| Bitter receptor gene (TAS2R38), 6-n-propylthiouracil (PROP) bitterness and alcohol intake. | Duffy VB et al. | β | 2004 | β |
| Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics. | Sullivan PF et al. | β | 2004 | β |
| Commentary on - Generalized estimating equations for association structures: familial correlations of lipid profiles | Franke D et al. | β | 2004 | β |
| Confirmation and fine mapping of the chromosome 1 alcohol dependence risk locus. | Lappalainen J et al. | β | 2004 | β |
| Estimating equations for association structures. | Yan J et al. | β | 2004 | β |
| Genes associated with addiction: alcoholism, opiate, and cocaine addiction. | Kreek MJ et al. | β | 2004 | β |
| Genetic approaches to alcohol dependence. | Ball D | β | 2004 | β |
| Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism. | Quertemont E | β | 2004 | β |
| Genetics and alcoholism among at-risk relatives II: interest and concerns about hypothetical genetic testing for alcoholism risk. | Gamm JL et al. | β | 2004 | β |
| Genetics and drug use as a complex phenotype. | Lessov CN et al. | β | 2004 | β |
| Genetics, pharmacokinetics, and neurobiology of adolescent alcohol use. | β | β | 2004 | β |
| Genetic study of alcoholism and novel gene expression in the alcoholic brain. | Fan L et al. | β | 2004 | β |
| Genomic screen for loci associated with alcohol dependence in Mission Indians. | Ehlers CL et al. | β | 2004 | β |
| Molecular genetics of substance abuse vulnerability: remarkable recent convergence of genome scan results. | Uhl GR | β | 2004 | β |
| Molecular genetic underpinnings of human substance abuse vulnerability: likely contributions to understanding addiction as a mnemonic process. | Uhl GR | β | 2004 | β |
| Possible epistatic role of ADH7 in the protection against alcoholism. | Osier MV et al. | β | 2004 | β |
| Re-analysis of collaborative study on the genetics of alcoholism pedigrees suggests the presence of loci influencing novelty-seeking near D12S391 and D17S1299. | Curtis D | β | 2004 | β |
| Re: KC Wilhelmsen, M Schuckit et al (2003): the search for genes related to a low-level response to alcohol determined by alcohol challenges. | Soyka M | β | 2004 | β |
| Results of a genomewide linkage scan: support for chromosomes 9 and 11 loci increasing risk for cigarette smoking. | Gelernter J et al. | β | 2004 | β |
| The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuse. | Lin Z et al. | β | 2004 | β |
| Theodore Reich, M.D. (1938-2003): in memoriam. | DeLisi LE | β | 2004 | β |
| Theodore Reich, M.D.: October 14, 1938-December 25, 2003. | Suarez BK et al. | β | 2004 | β |
| The search for genes contributing to the low level of response to alcohol: patterns of findings across studies. | Schuckit MA et al. | β | 2004 | β |
| The search for genetic risk factors associated with suicidal behavior. | Hesselbrock V et al. | β | 2004 | β |
| Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. | Edenberg HJ et al. | β | 2004 | β |
| Age and birth cohort effects on rates of alcohol dependence. | Rice JP et al. | β | 2003 | β |
| A genome-wide search for quantitative trait loci influencing substance dependence vulnerability in adolescence. | Stallings MC et al. | β | 2003 | β |
| Alcohol addiction research: from animal models to clinics. | Spanagel R | β | 2003 | β |
| Alcohol dependence among Alaskan natives and their health care utilization. | Hesselbrock VM et al. | β | 2003 | β |
| Allelic variation at alcohol metabolism genes ( ADH1B, ADH1C, ALDH2) and alcohol dependence in an American Indian population. | Mulligan CJ et al. | β | 2003 | β |
| alpha-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats. | Liang T et al. | β | 2003 | β |
| Analyses of quantitative trait loci contributing to alcohol preference in HAD1/LAD1 and HAD2/LAD2 rats. | Carr LG et al. | β | 2003 | β |
| Arguments for the genetic basis of the bipolar spectrum. | Kelsoe JR | β | 2003 | β |
| A simple nonparametric test for linkage with sib-pair censored event time observations. | Wei E et al. | β | 2003 | β |
| Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. | Song J et al. | β | 2003 | β |
| Autism families with a high incidence of alcoholism. | Miles JH et al. | β | 2003 | β |
| Candidate genes for alcohol dependence: a review of genetic evidence from human studies. | Dick DM et al. | β | 2003 | β |
| Classification of alcohol use disorders. | Hasin D | β | 2003 | β |
| Confirmation of alcohol preference quantitative trait loci in the replicate high alcohol drinking and low alcohol drinking rat lines. | Foroud T et al. | β | 2003 | β |
| Genetic analysis workshop 13: Summary of analyses of alcohol and cigarette use phenotypes in the Framingham Heart Study. | Saccone NL et al. | β | 2003 | β |
| Genetic and environmental influences on human psychological differences. | Bouchard TJ et al. | β | 2003 | β |
| Genetics of behaviour: phenotypic and molecular study of rats derived from high- and low-alcohol consuming lines. | Terenina-Rigaldie E et al. | β | 2003 | β |
| Genome-wide linkage survey for genetic loci that influence the development of depressive disorders in families with recurrent, early-onset, major depression. | Zubenko GS et al. | β | 2003 | β |
| Genome-wide screen for heavy alcohol consumption. | Wyszynski DF et al. | β | 2003 | β |
| Genomic regions linked to alcohol consumption in the Framingham Heart Study. | Bergen AW et al. | β | 2003 | β |
| Introduction: National Institute on Alcohol Abuse and Alcoholism workshop on treatment research priorities and health disparities. | Le Fauve CE et al. | β | 2003 | β |
| Investigation of DUSP8 and CALCA in alcohol dependence. | Hink RL et al. | β | 2003 | β |
| Linkage mapping of beta 2 EEG waves via non-parametric regression. | Ghosh S et al. | β | 2003 | β |
| Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure. | Ma JZ et al. | β | 2003 | β |
| Pharmacogenomics of alcohol response and addiction. | Enoch MA | β | 2003 | β |
| Pleiotropic effect of a locus on chromosome 4 influencing alcohol drinking and emotional reactivity in rats. | Terenina-Rigaldie E et al. | β | 2003 | β |
| Protective association of genetic variation in alcohol dehydrogenase with alcohol dependence in Native American Mission Indians. | Wall TL et al. | β | 2003 | β |
| Psychopathology in the postgenomic era. | Plomin R et al. | β | 2003 | β |
| The genetics of smoking related behavior: a brief review. | Li MD | β | 2003 | β |
| A genome-wide scan shows significant linkage between bipolar disorder and chromosome 12q24.3 and suggestive linkage to chromosomes 1p22-21, 4p16, 6q14-22, 10q26 and 16p13.3. | Ewald H et al. | β | 2002 | β |
| A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. | Osier MV et al. | β | 2002 | β |
| A multi-incident, Old-Order Amish family with PD. | Racette BA et al. | β | 2002 | β |
| Antisocial alcoholism and serotonin-related polymorphisms: association tests. | Hill EM et al. | β | 2002 | β |
| A proline-threonine substitution in codon 351 of ADH1C is common in Native Americans. | Osier MV et al. | β | 2002 | β |
| Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice. | Choi DS et al. | β | 2002 | β |
| Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism. | Bierut LJ et al. | β | 2002 | β |
| Dopamine D 4 receptor gene polymorphism and extraversion revisited: results from the Munich gene bank project for alcoholism. | Soyka M et al. | β | 2002 | β |
| Effects of the interaction between genotype and environment. Research into the genetic epidemiology of alcohol dependence. | Heath AC et al. | β | 2002 | β |
| Implications of multifactorial inheritance for identification of genetic mechanisms in major psychiatric disorders. | Nurnberger JI | β | 2002 | β |
| Is there a genetic relationship between alcoholism and depression? | Nurnberger JI et al. | β | 2002 | β |
| Life-history theory and risky drinking. | Hill EM et al. | β | 2002 | β |
| Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. | Porjesz B et al. | β | 2002 | β |
| Linkage for platelet monoamine oxidase (MAO) activity: results from a replication sample. | Saccone NL et al. | β | 2002 | β |
| Neurodevelopmental liabilities in alcohol dependence: central serotonin and dopamine dysfunction. | Naranjo CA et al. | β | 2002 | β |
| Sex differences in the genetic risk for alcoholism. | Prescott CA | β | 2002 | β |
| Substance abuse vulnerability loci: converging genome scanning data. | Uhl GR et al. | β | 2002 | β |
| Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype. | Dick DM et al. | β | 2002 | β |
| Syndrome profiles in alcoholism and panic disorder with or without agoraphobia: an explorative family study. | Davids E et al. | β | 2002 | β |
| The collaborative study on the genetics of alcoholism: an update. | Edenberg HJ | β | 2002 | β |
| The DRD4 VNTR polymorphism moderates craving after alcohol consumption. | Hutchison KE et al. | β | 2002 | β |
| The genetics of tobacco use: methods, findings and policy implications. | Hall W et al. | β | 2002 | β |
| The self-perceived survival ability and reproductive fitness (SPFit) theory of substance use disorders. | Newlin DB | β | 2002 | β |
| The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report. | Bennett P et al. | β | 2002 | β |
| Voluntary ethanol consumption by mice: genome-wide analysis of quantitative trait loci and their interactions in a C57BL/6ByJ x 129P3/J F2 intercross. | Bachmanov AA et al. | β | 2002 | β |
| A bootstrapped commingling analysis of platelet monoamine oxidase activity levels corrected for cigarette smoking. | Daw EW et al. | β | 2001 | β |
| A comparison of correlates of DSM-IV alcohol abuse or dependence among more than 400 sons of alcoholics and controls. | Schuckit MA et al. | β | 2001 | β |
| A genome-wide search for genes that relate to a low level of response to alcohol. | Schuckit MA et al. | β | 2001 | β |
| An integrative approach for studying the etiology of alcoholism and other addictions. | Jacob T et al. | β | 2001 | β |
| Confirmation that offspring from families with alcohol-dependent individuals have greater hypothalamic-pituitary-adrenal axis activation induced by naloxone compared with offspring without a family history of alcohol dependence. | Wand G et al. | β | 2001 | β |
| Drug abuse and dependency: understanding gender differences in etiology and management. | Wasilow-Mueller S et al. | β | 2001 | β |
| Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder. | Nurnberger JI et al. | β | 2001 | β |
| Genetic analysis of the mu-opioid receptor in alcohol-dependent individuals. | Rommelspacher H et al. | β | 2001 | β |
| Genomewide scans of complex human diseases: true linkage is hard to find. | AltmΓΌller J et al. | β | 2001 | β |
| Liver transplantation for alcoholic cirrhosis: long term follow-up and impact of disease recurrence. | Bellamy CO et al. | β | 2001 | β |
| Multipoint development of the weighted pairwise correlation (WPC) linkage method for pedigrees of arbitrary size and application to the analysis of breast cancer and alcoholism familial data. | Zinn-Justin A et al. | β | 2001 | β |
| P300 event-related potential amplitude as an endophenotype of alcoholism--evidence from the collaborative study on the genetics of alcoholism. | Hesselbrock V et al. | β | 2001 | β |
| Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms. | Uhl GR et al. | β | 2001 | β |
| Recent research on alcohol tolerance and dependence. | Suwaki H et al. | β | 2001 | β |
| The genetics of alcoholism and alcohol abuse. | Enoch MA et al. | β | 2001 | β |
| Towards a molecular epidemiology of alcohol dependence: analysing the interplay of genetic and environmental risk factors. | Heath AC et al. | β | 2001 | β |
| Use of genetic analyses to refine phenotypes related to alcohol tolerance and dependence. | Crabbe JC | β | 2001 | β |
| Variation in alcohol pharmacokinetics as a risk factor for alcohol dependence. | Whitfield JB et al. | β | 2001 | β |
| Age and sex based genetic locus heterogeneity in type 1 diabetes. | Paterson AD et al. | β | 2000 | β |
| A genome screen of maximum number of drinks as an alcoholism phenotype. | Saccone NL et al. | β | 2000 | β |
| Alcohol genetics: will the promise be fulfilled? | Cook C | β | 2000 | β |
| Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. | Foroud T et al. | β | 2000 | β |
| Animal models in alcohol research. | Tabakoff B et al. | β | 2000 | β |
| Antisociality, substance dependence, and the DRD5 gene: a preliminary study. | Vanyukov MM et al. | β | 2000 | β |
| Anxiety and sensitivity to ethanol and pentobarbital in alcohol withdrawal seizure-prone and withdrawal seizure-resistant mice. | Atkins AL et al. | β | 2000 | β |
| Association analysis of the GABA(A) receptor subunit genes cluster on 5q33-34 and alcohol dependence in a Japanese population. | Loh EW et al. | β | 2000 | β |
| Association between the functional polymorphism of catechol-O-methyltransferase gene and alcohol consumption among social drinkers. | Kauhanen J et al. | β | 2000 | β |
| Biological phenotypes associated with individuals at high risk for developing alcohol-related disorders: Part 1. | Hill SY | β | 2000 | β |
| Confirmation of an excess of the high enzyme activity COMT val allele in heroin addicts in a family-based haplotype relative risk study. | Horowitz R et al. | β | 2000 | β |
| Co-occurring risk factors for alcohol dependence and habitual smoking. | Bierut LJ et al. | β | 2000 | β |
| Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking. | Bierut LJ et al. | β | 2000 | β |
| Frontal P300 decrements, alcohol dependence, and antisocial personality disorder. | Costa L et al. | β | 2000 | β |
| Genes and addiction. | Nestler EJ | β | 2000 | β |
| Genetics of the risk for alcoholism. | Schuckit MA | β | 2000 | β |
| Genetic studies of substance abuse. | Vanyukov MM et al. | β | 2000 | β |
| Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene. | Vandenbergh DJ et al. | β | 2000 | β |
| Mapping of quantitative trait loci for ethanol preference in quasi-congenic strains. | Vadasz C et al. | β | 2000 | β |
| Multipoint linkage analysis of the pseudoautosomal regions, using affected sibling pairs. | Dupuis J et al. | β | 2000 | β |
| Pharmacogenomics and addiction to opiates. | Lichtermann D et al. | β | 2000 | β |
| Psychiatric genetics: back to the future. | Owen MJ et al. | β | 2000 | β |
| Transition to alcohol dependence: clinical and neurobiological considerations. | Schmidt LG et al. | β | 2000 | β |
| Why do some people drink too much? The role of genetic and psychosocial influences. | β | β | 2000 | β |
| A genome-wide search for susceptibility genes linked to alcohol dependence. | Peterson LE et al. | β | 1999 | β |
| Alcohol and genetics: new animal models. | Browman KE et al. | β | 1999 | β |
| Alcoholism as a complex trait: comparison of genetic models and role of epidemiological risk factors. | Macciardi F et al. | β | 1999 | β |
| A logistic regression extension of the transmission disequilibrium test for continuous traits: application to linkage disequilibrium between alcoholism and the candidate genes DRD2 and ADH3. | Waldman ID et al. | β | 1999 | β |
| A more powerful method to evaluate p-values in GENEHUNTER. | Zhao H et al. | β | 1999 | β |
| A multiple locus analysis of the collaborative study on the genetics of alcoholism data set. | Lin S et al. | β | 1999 | β |
| Analyses of the COGA data set in one ethnic group with examinations of alternative definitions of alcoholism. | Sheffield LJ et al. | β | 1999 | β |
| Application of an ordered subset analysis approach to the genetics of alcoholism. | Watanabe RM et al. | β | 1999 | β |
| Assessing linkage of monoamine oxidase B in a genome-wide scan using a univariate variance components approach. | Barnholtz JS et al. | β | 1999 | β |
| Association and linkage analysis of ICD-10 diagnosis for alcoholism. | Tiwari HK et al. | β | 1999 | β |
| Basic concepts in the study of diseases with complex genetics. | Burmeister M | β | 1999 | β |
| Chromosome 4 Workshop Summary: Sixth World Congress on Psychiatric Genetics, Bonn, Germany, October 6-10, 1998. | Kennedy JL et al. | β | 1999 | β |
| Chromosome 6 workshop report. | Nurnberger JI et al. | β | 1999 | β |
| Chromosomes 12 and 16 workshop. | Detera-Wadleigh SD | β | 1999 | β |
| Chromosomes 1, 2, and 7 workshop. | Hallmayer J | β | 1999 | β |
| Chromosome Workshop: chromosomes 11, 14, and 15. | Craddock N et al. | β | 1999 | β |
| Correcting for ascertainment bias in the COGA data set. | Comuzzie AG et al. | β | 1999 | β |
| Design of artificial neural network and its applications to the analysis of alcoholism data. | Li W et al. | β | 1999 | β |
| Evidence of linkage in subtypes of alcoholism. | MΓ©rette C et al. | β | 1999 | β |
| Exploring genetic analysis of complex traits through the paradigm of alcohol dependence: summary of GAW11 contributions. | Almasy L et al. | β | 1999 | β |
| Exploring linkage for alcoholism using affection status and quantitative event related potential phenotypes. | Lunetta KL et al. | β | 1999 | β |
| Exploring the impact of extended phenotype in stratified samples. | Kovac I et al. | β | 1999 | β |
| Familial analysis of event related potentials. | King TM et al. | β | 1999 | β |
| Genetics of alcoholism and substance abuse. | Enoch MA et al. | β | 1999 | β |
| Genetic studies of alcoholism and substance dependence. | Reich T et al. | β | 1999 | β |
| Genome scans for genetic predisposition to alcoholism by use of transmission disequilibrium test analyses. | Page GP et al. | β | 1999 | β |
| Genome screen for platelet monoamine oxidase (MAO) activity. | Saccone NL et al. | β | 1999 | β |
| Genome search for alcohol dependence using the weighted pairwise correlation linkage method: interesting findings on chromosome 4. | Zinn-Justin A et al. | β | 1999 | β |
| Haplotype analysis in the Collaborative Study on the Genetics of Alcoholism data: double recombinants. | Petronis A et al. | β | 1999 | β |
| Human chromosomes 11p15 and 4p12 and alcohol dependence: possible association with the GABRB1 gene. | Parsian A et al. | β | 1999 | β |
| Identification and confirmation of quantitative trait loci regulating alcohol consumption in congenic strains of mice. | Whatley VJ et al. | β | 1999 | β |
| Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism. | Chen CC et al. | β | 1999 | β |
| Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials. | Williams JT et al. | β | 1999 | β |
| Linkage analysis in alcohol dependence. | Windemuth C et al. | β | 1999 | β |
| Linkage and association analyses of alcoholism using a regression-based transmission/disequilibrium test. | George V et al. | β | 1999 | β |
| Linkage of chromosome 1 markers to alcoholism-related phenotypes by sib pair linkage analysis of principal components. | Olson JM et al. | β | 1999 | β |
| Linkage studies of D2 and D4 receptor genes and alcoholism. | Hill SY et al. | β | 1999 | β |
| Mapping alcoholism genes using linkage/linkage disequilibrium analysis. | Aragaki C et al. | β | 1999 | β |
| Model-based and model-free multipoint genome-wide linkage analysis of alcoholism. | Jacobs KB et al. | β | 1999 | β |
| Nonparametric linkage analysis of alcohol dependence with chromosome 1 and 7 markers. | D'Alfonso S | β | 1999 | β |
| Phenotyping alcoholism. | McGue M | β | 1999 | β |
| Possible linkage of alcoholism, monoamine oxidase activity and P300 amplitude to markers on chromosome 12q24. | Juo SH et al. | β | 1999 | β |
| Quantitative trait linkage mapping in anthropology. | Rogers J et al. | β | 1999 | β |
| Report of the chromosome 18 workshop. | Van Broeckhoven C et al. | β | 1999 | β |
| Sex-based linkage analysis of alcoholism. | Paterson AD et al. | β | 1999 | β |
| Sib-pair linkage analyses of alcoholism: dichotomous and quantitative measures. | Korczak JF et al. | β | 1999 | β |
| Sib-pair linkage analysis of alcohol dependence taking into account covariates and age-of-onset variability: evaluation of the residual approach. | Tores F et al. | β | 1999 | β |
| Sixth World Congress of Psychiatric Genetics X Chromosome Workshop. | Paterson AD | β | 1999 | β |
| Structural decomposition of genetic diversity in families with alcoholism. | Stassen HH et al. | β | 1999 | β |
| The impact of redefining affection status for alcoholism on affected-sib-pair analysis. | Fann CS et al. | β | 1999 | β |
| Transmission ratio distortion in females on chromosome 10p11-p15. | Paterson AD et al. | β | 1999 | β |
| Using recursive partitioning for exploration and follow-up of linkage and association analyses. | Wilcox MA et al. | β | 1999 | β |
| Whole genome association studies for genes affecting alcohol dependence. | Sun F et al. | β | 1999 | β |
| Anxiety proneness linked to epistatic loci in genome scan of human personality traits. | Cloninger CR et al. | β | 1998 | β |
| Application of a bogus testing procedure to determine college students' utilization of genetic screening for alcoholism. | Thombs DL et al. | β | 1998 | β |
| Genetics of alcoholism. | Edenberg HJ | β | 1998 | β |
| Linkage of an alcoholism-related severity phenotype to chromosome 16. | Foroud T et al. | β | 1998 | β |
| Molecular biology of alcohol dependence, a complex polygenic disorder. | Whitfield JB et al. | β | 1998 | β |
| The genetics of alcoholism. | Goate AM et al. | β | 1998 | β |