type 2 diabetes phenotype
Evidence from:
primary |
all sources
Related entities (64)
Mentioned in (146)
Papers in which this entity is mentioned.
- Cardiovascular and Metabolic Outcomes in Adults with Fetal Alcohol Spectrum Disorders: A Retrospective Cohort Study. (2026)
- Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs. (2025)
- Associations between common genetic variants and income provide insights about the socio-economic health gradient. (2025)
- Concordance between male- and female-specific GWAS results helps define underlying genetic architecture of complex traits. (2025)
- Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. (2025)
- Genome-wide association testing beyond SNPs. (2025)
- Parent-of-origin effects on complex traits in up to 236,781 individuals. (2025)
- Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI. (2024)
- Yield of genetic association signals from genomes, exomes and imputation in the UK Biobank. (2024)
- Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases. (2024)
- Principles and methods for transferring polygenic risk scores across global populations. (2024)
- CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods. (2024)
- Recent advances in polygenic scores: translation, equitability, methods and FAIR tools. (2024)
- An overview of DNA methylation-derived trait score methods and applications. (2023)
- Effect of exposure to maternal diabetes during pregnancy on offspring's brain cortical thickness and neurocognitive functioning. (2023)
- Biobank-scale methods and projections for sparse polygenic prediction from machine learning. (2023)
- Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders. (2023)
- Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. (2022)
- Variant interpretation using population databases: Lessons from gnomAD. (2022)
- Untargeted Metabolome Analysis Reveals Reductions in Maternal Hepatic Glucose and Amino Acid Content That Correlate with Fetal Organ Weights in a Mouse Model of Fetal Alcohol Spectrum Disorders. (2022)
- Rodent models in placental research. Implications for fetal origins of adult disease. (2022)
- Aging-Related Behavioral, Adiposity, and Glucose Impairments and Their Association following Prenatal Alcohol Exposure in the C57BL/6J Mouse. (2022)
- Med-BERT: pretrained contextualized embeddings on large-scale structured electronic health records for disease prediction. (2021)
- Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group. (2021)
- Associations Between Exposure to Gestational Diabetes Mellitus In Utero and Daily Energy Intake, Brain Responses to Food Cues, and Adiposity in Children. (2021)
- Placental genomic risk scores and early neurodevelopmental outcomes. (2021)
- Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. (2021)
- Detecting cell-type-specific allelic expression imbalance by integrative analysis of bulk and single-cell RNA sequencing data. (2021)
- Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. (2021)
- Macrophage Polarization States in the Tumor Microenvironment. (2021)
- Studying the Effect of Maternal Pregestational Diabetes on Fetal Neurodevelopment Using Magnetoencephalography. (2020)
- Polygenic risk scores: from research tools to clinical instruments. (2020)
- Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood. (2020)
- TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson's Disease. (2020)
- Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. (2020)
- Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks. (2020)
- The mutational constraint spectrum quantified from variation in 141,456 humans. (2020)
- Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative review. (2020)
- Detecting cell-type-specific allelic expression imbalance by integrative analysis of bulk and single-cell RNA sequencing data (2020)
- Polygenic prediction via Bayesian regression and continuous shrinkage priors. (2019)
- Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders. (2019)
- Associations of Maternal Diabetes and Body Mass Index With Offspring Birth Weight and Prematurity. (2019)
- Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. (2019)
- Determining cell type abundance and expression from bulk tissues with digital cytometry. (2019)
- The mutational constraint spectrum quantified from variation in 141,456 humans (2019)
- Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019)
- The Comparative Effectiveness of Mobile Phone Interventions in Improving Health Outcomes: Meta-Analytic Review. (2019)
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. (2018)
- The Gene Encoding Protocadherin 9 (PCDH9), a Novel Risk Factor for Major Depressive Disorder. (2018)
- Psychiatric Genomics: An Update and an Agenda. (2018)
- Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. (2018)
- Sex and gender differences in developmental programming of metabolism. (2018)
- Neuroepigenetics and addiction. (2018)
- Human Brain Abnormalities Associated With Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder. (2017)
- Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017)
- The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). (2017)
- Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential. (2017)
- Dysregulation of Cortical Neuron DNA Methylation Profile in Autism Spectrum Disorder. (2017)
- Prenatal alcohol exposure and prenatal stress differentially alter glucocorticoid signaling in the placenta and fetal brain. (2017)
- Translating genome-wide association findings into new therapeutics for psychiatry. (2016)
- Gray matter maturation and cognition in children with different APOE ε genotypes. (2016)
- Abnormal Eating Behaviors Are Common in Children with Fetal Alcohol Spectrum Disorder. (2016)
- Alcohol-Induced Developmental Origins of Adult-Onset Diseases. (2016)
- Enacting the molecular imperative: How gene-environment interaction research links bodies and environments in the post-genomic age. (2016)
- Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants. (2016)
- Epidemiology, Etiology, and Treatment of Isolated Cleft Palate. (2016)
- Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. (2015)
- Pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. (2015)
- A gene-based association method for mapping traits using reference transcriptome data. (2015)
- What Happens When Children with Fetal Alcohol Spectrum Disorders Become Adults? (2015)
- An introductory review of parallel independent component analysis (p-ICA) and a guide to applying p-ICA to genetic data and imaging phenotypes to identify disease-associated biological pathways and systems in common complex disorders. (2015)
- Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis. (2015)
- Maternal periconceptional alcohol consumption and congenital limb deficiencies. (2014)
- Maternal obesity and tobacco use modify the impact of genetic variants on the occurrence of conotruncal heart defects. (2014)
- The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
- Heritability and genomics of gene expression in peripheral blood. (2014)
- The prevalence of confirmed maltreatment among US children, 2004 to 2011. (2014)
- Genetic variability in the regulation of gene expression in ten regions of the human brain. (2014)
- Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice. (2014)
- Impact of low dose prenatal ethanol exposure on glucose homeostasis in Sprague-Dawley rats aged up to eight months. (2013)
- A mega-analysis of genome-wide association studies for major depressive disorder. (2013)
- The PPAR α / γ Agonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid Utilization In Vivo in the Obese Zucker Rat. (2013)
- Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (2013)
- Effects of alcohol on the endocrine system. (2013)
- Dosage transmission disequilibrium test (dTDT) for linkage and association detection. (2013)
- Infant nutrition and later health: a review of current evidence. (2012)
- Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. (2012)
- Inflammaging: disturbed interplay between autophagy and inflammasomes. (2012)
- Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. (2012)
- Auditory brainstem response (ABR) abnormalities across the life span of rats prenatally exposed to alcohol. (2012)
- Effects of prenatal exposure to sodium arsenite on motor and food-motivated behaviors from birth to adulthood in C57BL6/J mice. (2012)
- Pathway analysis of genomic data: concepts, methods, and prospects for future development. (2012)
- Vitamin D and its role during pregnancy in attaining optimal health of mother and fetus. (2012)
- Implication of European-derived adiposity loci in African Americans. (2012)
- Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. (2012)
- Maternal nutritional status, C(1) metabolism and offspring DNA methylation: a review of current evidence in human subjects. (2012)
- A comparison of approaches to account for uncertainty in analysis of imputed genotypes. (2011)
- An Interdisciplinary Approach to Studying Gene-Environment Interactions: From Twin Studies to Gene Identification and Back. (2011)
- Candidate placental biomarkers for intrauterine alcohol exposure. (2011)
- MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven. (2011)
- Gene set analysis of genome-wide association studies: methodological issues and perspectives. (2011)
- Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. (2011)
- Alcohol consumption and non-communicable diseases: epidemiology and policy implications. (2011)
- Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. (2011)
- Epigenetics and psychoneuroimmunology: mechanisms and models. (2011)
- Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants. (2011)
- Prenatal alcohol exposure: fetal programming and later life vulnerability to stress, depression and anxiety disorders. (2010)
- Risks of overweight and abdominal obesity at age 16 years associated with prenatal exposures to maternal prepregnancy overweight and gestational diabetes mellitus. (2010)
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. (2010)
- Linking functional decline of telomeres, mitochondria and stem cells during ageing. (2010)
- METAL: fast and efficient meta-analysis of genomewide association scans. (2010)
- Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample. (2010)
- Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes. (2010)
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (2010)
- Obesity is linked with lower brain volume in 700 AD and MCI patients. (2010)
- The psychiatric GWAS consortium: big science comes to psychiatry. (2010)
- Using public control genotype data to increase power and decrease cost of case-control genetic association studies. (2010)
- Genome-wide association studies in diverse populations. (2010)
- The psychiatric GWAS consortium: big science comes to psychiatry. (2010)
- Maternal folate-related gene environment interactions and congenital heart defects. (2010)
- Chronic ethanol consumption-induced pancreatic {beta}-cell dysfunction and apoptosis through glucokinase nitration and its down-regulation. (2010)
- The genetic interpretation of area under the ROC curve in genomic profiling. (2010)
- Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model. (2010)
- Reduced cortical folding in mental retardation. (2010)
- Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. (2009)
- The epigenetics of sex differences in the brain. (2009)
- Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. (2009)
- Meta-analysis in genome-wide association studies. (2009)
- Finding the missing heritability of complex diseases. (2009)
- Genomewide association studies: history, rationale, and prospects for psychiatric disorders. (2009)
- Genome-wide association studies in ADHD. (2009)
- Developmental origins of health and disease: brief history of the approach and current focus on epigenetic mechanisms. (2009)
- Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
- Marker selection for genetic case-control association studies. (2009)
- New insights into the genetics of addiction. (2009)
- Adrenomedullin signaling is necessary for murine lymphatic vascular development. (2008)
- 3' end mRNA processing: molecular mechanisms and implications for health and disease. (2008)
- Effect of in utero and early-life conditions on adult health and disease. (2008)
- Heterogeneity in meta-analyses of genome-wide association investigations. (2007)
- DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. (2007)
- Ethanol inhibits insulin expression and actions in the developing brain. (2005)
- C-reactive protein: a critical update. (2003)
- Mechanisms for the pleiotropic effects of the agouti gene. (1995)
- Coordinate expression of insulin-like growth factor system components by neurons and neuroglia during retinal and cerebellar development. (1992)
Merged raw entities (7)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| type 2 diabetes | phenotype | 100 | 220 |
| type 2 diabetes mellitus | phenotype | 31 | 51 |
| type ii diabetes | phenotype | 21 | 42 |
| t2d | phenotype | 15 | 85 |
| type-2 diabetes | phenotype | 6 | 10 |
| non-insulin-dependent diabetes | phenotype | 1 | 1 |
| niddm | phenotype | — | — |