Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits.

paper Cited Public

Authors: Caspi, Avshalom; Hariri, Ahmad R; Holmes, Andrew; Uher, Rudolf; Moffitt, Terrie E
Year: 2010
Journal: The American journal of psychiatry
PMID: 20231323
DOI: 10.1176/appi.ajp.2010.09101452
PMCID: PMC2943341

#	Section	Preview
20	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Nonhuman Primate Studies	Another major parallel between the human and monkey data has been the finding that, as in humans,…
21	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Nonhuman Primate Studies	recent data from S-carrier monkeys (88) and 5-HTT mutant mice (91) demonstrating that reversal…
22	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Studies Involving Genetically Engineered 5-HTT Mutations in Rodents	Research using rodents allows for experimental control over genetic background and the environment…
23	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Studies Involving Genetically Engineered 5-HTT Mutations in Rodents	Mice in which the 5-HTT has been functionally excised either by targeted mutation or chemical…
24	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Studies Involving Genetically Engineered 5-HTT Mutations in Rodents	The “depression-related” consequences of rodent 5-HTT knockout mice are, at first blush, less…
25	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Studies Involving Genetically Engineered 5-HTT Mutations in Rodents	Much of our understanding of the functional role of the 5-HTT as a master modulator of the 5-HT…
26	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Studies Involving Genetically Engineered 5-HTT Mutations in Rodents	in dendritic arborization of prefrontal cortex neurons (56). The implication here is that influence…
27	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Studies Involving Genetically Engineered 5-HTT Mutations in Rodents	An intriguing line of enquiry in this context has centered on the hypothesis that 5-HTT variation…
28	Evidence for the 5-HTT Stress Sensitivity Hypothesis — Studies Involving Genetically Engineered 5-HTT Mutations in Rodents	These findings raise the question of whether the effects of 5-HTT knockout are developmentally…
29	Lessons for G×E Research	In the previous section, we reviewed evidence about the 5-HTT stress-sensitivity hypothesis. Lessons…
30	Lessons for G×E Research — G×E Hypotheses Can Be Tested With Large and Small Samples	Statistical power is critical for theory-free, exploratory scans for G×E interactions (110). This…
31	Lessons for G×E Research — G×E Hypotheses Can Be Tested With Large and Small Samples	The problem has to do with the approach to testing interactions (111): If the product term (i.e.,…
32	Lessons for G×E Research — G×E Hypotheses Can Be Tested With Large and Small Samples	case where minor allele frequency and exposure rate equal 50% (bottom of Figure 3). An implication…
33	Lessons for G×E Research — G×E Research Can Be Carried Out Before as Well as After Replicated Gene Discovery	Some researchers claim that G×E studies should only be carried out if there exists a…
34	Lessons for G×E Research — G×E Research Can Be Carried Out Before as Well as After Replicated Gene Discovery	The Psychiatric GWAS Consortium (118) recommends conducting G×E studies only after convincing…
35	Lessons for G×E Research — G×E Research Is a Helpful Tool for Gene Discovery	Although most G×E research uses candidate genes, environmental exposures can also be used to…
36	Lessons for G×E Research — G×E Research Is a Helpful Tool for Gene Discovery	genes associated with the physiological response to psychological stress, particularly in the HPA…
37	Lessons for G×E Research — G×E Research Is a Helpful Tool for Gene Discovery	Research on “candidate environmental risks” can be combined with theory-free genetics to…
38	Lessons for G×E Research — G×E Research Is a Helpful Tool for Gene Discovery	The new generation of purpose-built Gene-Environment-Wide Interaction studies may be an improvement…
39	Lessons for G×E Research — G×E Research Is a Helpful Tool for Gene Discovery	A second way in which environmental exposures can be used to discover novel loci is to study gene…

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In this knowledge base

Title	Year	PMID
Prevention of Early Substance Use Mediates, and Variation at SLC6A4 Moderates, SAAF Intervention Effects on OXTR Methylation.	2018	27655391
The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood.	2017	27991676
GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures.	2015	26250693
Genetic determinants of depression: recent findings and future directions.	2015	25563565
Beyond genotype: serotonin transporter epigenetic modification predicts human brain function.	2014	25086606
Differential sensitivity to prevention programming: a dopaminergic polymorphism-enhanced prevention effect on protective parenting and adolescent substance use.	2014	23379386
The genetics of major depression.	2014	24507187
Candidate and non-candidate genes in behavior genetics.	2013	22878161
Combined role of childhood maltreatment, family history, and gender in the risk for alcohol dependence.	2013	22883538
Gender-specific gene-environment interaction in alcohol dependence: the impact of daily life events and GABRA2.	2013	23974430
Putting the 'epi' into epigenetics research in psychiatry.	2013	23572534
The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G × E effects.	2013	23473364
Cannabinoid receptor genotype moderation of the effects of childhood physical abuse on anhedonia and depression.	2012	22393204
The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-analyses to test developmental hypotheses about nicotine consumption.	2012	22492059
A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry.	2011	21890791
Gene-environment interaction in psychological traits and disorders.	2011	21219196
Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results.	2011	21439648
The influence of gene-environment interactions on alcohol consumption and alcohol use disorders: a comprehensive review.	2011	21530476
The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation.	2011	21199959
Genetically informative research on adolescent substance use: methods, findings, and challenges.	2010	21093770

External

Title	Authors	Journal	Year	Link
Adrenarche as a regulator of sensitivity to early adversity.	Herbert J	—	2026	→
Psychedelic experiences elicited by serotonergic psychedelics: Molecular mechanisms and functional connectivity changes in the brain.	Vollebregt R et al.	—	2026	→
Serotonergic modulation of excitatory synapse development and plasticity.	Chang VN et al.	—	2026	→
Differential susceptibility effects of the <i>5-HTTLPR</i> and <i>MAOA</i> genotypes on decision making under risk in the Iowa gambling task.	Rehn M et al.	—	2025	→
From Womb to Mind: Prenatal Epigenetic Influences on Mental Health Disorders.	Álvarez-Mejía D et al.	—	2025	→
Gene-Environment Interplay Between Perceived Stress and ADHD Symptoms in Adults.	Hur YM	—	2025	→
Hyperarousal, Dissociation, Emotion Dysregulation and Re-Experiencing-Towards Understanding Molecular Aspects of PTSD Symptoms.	Brzozowska A et al.	—	2025	→
Interaction between ghrelin and social support predicts antidepressant treatment outcomes in patients with depression.	Kim JM et al.	—	2025	→
Interleukin-1β rs16944 and rs1143627 polymorphisms and risk of developing major depressive disorder: A case-control study among Bangladeshi population.	Toma FM et al.	—	2025	→
Machine learning approach to DNA methylation and neuroimaging signatures as biomarkers for psychological resilience in young adults.	Lin SH et al.	—	2025	→
Metabolomics in Depression: What We Learn from Preclinical and Clinical Evidences.	Singh P et al.	—	2025	→
Molecular genetic basis of the primary emotions in young adults: an exploratory analysis of genetic polymorphisms across dopamine, serotonin, oxytocin, endogenous opioid, and neurotrophic factor pathways.	Glavač T et al.	—	2025	→
More and Less Fear in Serotonin Transporter Knockout Mice.	Lima J et al.	—	2025	→
NRXN3-NLGN1 complex influences the development of depression induced by maternal separation in rats.	Rong Y et al.	—	2025	→
Observer-rated environmental sensitivity and its characterization at behavioral, genetic, and physiological levels.	Weyn S et al.	—	2025	→
Rethinking Depression-Beyond Neurotransmitters: An Integrated Psychoneuroendocrineimmunology Framework for Depression's Pathophysiology and Tailored Treatment.	Bottaccioli AG et al.	—	2025	→
Serotonin modulates infraslow oscillation in the dentate gyrus during non-REM sleep.	Turi GF et al.	—	2025	→
The effects of life experiences and polygenic risk for depression on the development of positive and negative cognitive biases across adolescence: The CogBIAS hypothesis.	Zavlis O et al.	—	2025	→
The serotonin gene 5-HTTLPR and brain food-reward responses during sadness: a mood-induction neuroimaging study.	Markus CR et al.	—	2025	→
A Bibliometric and Visual Analysis of Single Nucleotide Polymorphism Studies in Depression.	Zhang Z et al.	—	2024	→
Advantageous early-life environments cushion the genetic risk for ischemic heart disease.	Baker S et al.	—	2024	→
Behavioural characteristics and sex differences of a treatment-resistant depression model: Chronic mild stress in the Wistar-Kyoto rat.	Loizeau V et al.	—	2024	→
Biocultural Aspects of Mental Distress: Expanding the Biomedical Model Towards an Integrative Biopsychosocial Understanding of Disorder.	Maximino C	—	2024	→
Biomarker adoption in developmental science: A data-driven modelling of trends from 90 biomarkers across 20 years.	Qian W et al.	—	2024	→
Differential impact of prenatal PTSD symptoms and preconception trauma exposure on placental <i>NR3C1</i> and <i>FKBP5</i> methylation.	Stroud LR et al.	—	2024	→
Gene-Environment Interactions in Irrational Beliefs: The Roles of Childhood Adversity and Multiple Candidate Genes.	Chiș A et al.	—	2024	→
Genetic Variation and Stroke Recovery: The STRONG Study.	Cramer SC et al.	—	2024	→
Individuals being high in their sensitivity to the environment: Are sensitive period changes in play?	Homberg JR et al.	—	2024	→
Patient experiences of treatment-resistant depression (TRD): A systematic review and qualitative meta-synthesis.	Cernat A et al.	—	2024	→
Pharmacogenetics of selective serotonin reuptake inhibitors (SSRI): A serotonin reuptake transporter (SERT)-based approach.	Sreeja V et al.	—	2024	→
Serotonin transporter knockout in rats reduces beta- and gamma-band functional connectivity between the orbitofrontal cortex and amygdala during auditory discrimination.	Boillot M et al.	—	2024	→
The Association between Post-Traumatic Stress Disorder, 5HTTLPR, and the Role of Ethnicity: A Meta-Analysis.	Landoni M et al.	—	2024	→
The parent's and the child's internal working models of each other moderate cascades from child difficulty to socialization outcomes: Preliminary evidence for dual moderation?	Kochanska G et al.	—	2024	→
The role of serotonin in depression-A historical roundup and future directions.	Bremshey S et al.	—	2024	→
Comparison of three common inbred mouse strains reveals substantial differences in hippocampal GABAergic interneuron populations and in vitro network oscillations.	Çalışkan G et al.	—	2023	→
Current status, challenges and future prospects in computational psychiatry: a narrative review.	Vasilchenko KF et al.	—	2023	→
Daily stress, and mental health of professional degree graduate students in Chinese traditional medicine universities: the mediating role of learning career adaptation.	Li L et al.	—	2023	→
Need for Multidimensional and Multidisciplinary Management of Depressed Preadolescents and Adolescents: A Review of Randomized Controlled Trials on Oral Supplementations (Omega-3, Fish Oil, Vitamin D<sub>3</sub>).	Pruneti C et al.	—	2023	→
Perinatal serotonergic manipulation shapes anhedonic and cognitive behaviors in a sex- and age-dependent manner: Identification of related biological functions at central and peripheral level.	Gallo MT et al.	—	2023	→
Progress and Challenges in GxE Research on Depression.	Belsky DW et al.	—	2023	→
Psychometric properties of the Hungarian childhood trauma questionnaire short form and its validity in patients with adult attention-deficit hyperactivity disorder or borderline personality disorder.	Kenézlői E et al.	—	2023	→
Reply to: "The serotonin theory of depression: a systematic umbrella review of the evidence" published by Moncrieff J, Cooper RE, Stockmann T, Amendola S, Hengartner MP, Horowitz MA in Molecular Psychiatry (2022 Jul 20. doi: 10.1038/s41380-022-01661-0).	Bartova L et al.	—	2023	→
Scales and Interventions for Resilience among Treatment-Seeking Patients with Depression: A Systematic Review.	Jayakrishnan K et al.	—	2023	→
Serotonin Transporter (SERT) Expression Modulates the Composition of the Western-Diet-Induced Microbiota in Aged Female Mice.	Bloemendaal M et al.	—	2023	→
Alterations of mitochondrial dynamics in serotonin transporter knockout rats: A possible role in the fear extinction recall mechanisms.	Brivio P et al.	—	2022	→
A neural model of vulnerability and resilience to stress-related disorders linked to differential susceptibility.	Homberg JR et al.	—	2022	→
Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine?	Carhart-Harris RL et al.	—	2022	→
Childhood Maltreatment, Automatic Negative Thoughts, and Resilience: The Protective Roles of Culture and Genes.	Yu M et al.	—	2022	→
Differential Relations of Parental Behavior to Children's Early Executive Function as a Function of Child Genotype: A Systematic Review.	Vrantsidis DM et al.	—	2022	→
From temperament and parenting to attachment: a review of the interplay of gene and environment factors in the developmental pathway to attachment.	Shah S et al.	—	2022	→
Infants' attachment security and children's self-regulation within and outside the parent-child relationship at kindergarten age: Distinct paths for children varying in anger proneness.	Bendel-Stenzel LC et al.	—	2022	→
Parenting and the Serotonin Transporter Gene (5HTTLPR), Is There an Association? A Systematic Review of the Literature.	Landoni M et al.	—	2022	→
Reactive vs proactive aggression: A differential psychobiological profile? Conclusions derived from a systematic review.	Romero-Martínez Á et al.	—	2022	→
Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons.	De Gregorio R et al.	—	2022	→
The Molecular Genetics of Dissociative Symptomatology: A Transdiagnostic Literature Review.	Rajkumar RP	—	2022	→
Tryptophan metabolites in depression: Modulation by gut microbiota.	Lukić I et al.	—	2022	→
A Developmental Framework for Embodiment Research: The Next Step Toward Integrating Concepts and Methods.	Lux V et al.	—	2021	→
Amygdala Circuit Substrates for Stress Adaptation and Adversity.	Zhang WH et al.	—	2021	→
A Novel Application of Ketamine for Improving Perioperative Sleep Disturbances.	Song B et al.	—	2021	→
Associations of age, sex, sexual abuse, and genotype with monoamine oxidase a gene methylation.	Checknita D et al.	—	2021	→
Child development with the D-score: turning milestones into measurement.	van Buuren S et al.	—	2021	→
Classical Psychedelics as Therapeutics in Psychiatry - Current Clinical Evidence and Potential Therapeutic Mechanisms in Substance Use and Mood Disorders.	Mertens LJ et al.	—	2021	→
COVID-19-Related Daily Stress Processes in College-Aged Adults: Examining the Role of Depressive Symptom Severity.	Greaney JL et al.	—	2021	→
Cumulative procedural pain and brain development in very preterm infants: A systematic review of clinical and preclinical studies.	Boggini T et al.	—	2021	→
Does Psychedelic Therapy Have a Transdiagnostic Action and Prophylactic Potential?	Kočárová R et al.	—	2021	→
Early Rearing Conditions Affect Monoamine Metabolite Levels During Baseline and Periods of Social Separation Stress: A Non-human Primate Model (<i>Macaca mulatta</i>).	Wood EK et al.	—	2021	→
Exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice.	Wilson C et al.	—	2021	→
Genes, Environments, and Time: The Biology of Adversity and Resilience.	Boyce WT et al.	—	2021	→
How does the 'environment' come to the person? The 'ecology of the person' and addiction.	Tretter F et al.	—	2021	→
Mechanisms of the Rapid Effects of Ketamine on Depression and Sleep Disturbances: A Narrative Review.	Song B et al.	—	2021	→
Organic Cation Transporters in Psychiatric Disorders.	Daws LC	—	2021	→
Prospective Relations between Parents' Depressive Symptoms and Children's Attributional Style.	Sutherland S et al.	—	2021	→
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms.	Inserra A et al.	—	2021	→
Recovery of menses after functional hypothalamic amenorrhoea: if, when and why.	Pape J et al.	—	2021	→
Resilience to anhedonia-passive coping induced by early life experience is linked to a long-lasting reduction of I<sub>h</sub> current in VTA dopaminergic neurons.	D'Addario SL et al.	—	2021	→
Serotonergic sensitivity alleles moderate relations between attachment security at age three and socioemotional competence at age five.	Lee JK et al.	—	2021	→
Serotonin Receptor and Transporter Endocytosis Is an Important Factor in the Cellular Basis of Depression and Anxiety.	Deo N et al.	—	2021	→
Stress sensitization to depression following childhood adversity: Moderation by HPA axis and serotonergic multilocus profile scores.	Starr LR et al.	—	2021	→
The Association between Neighborhood Disorder and Health: Exploring the Moderating Role of Genotype and Marriage.	Lei MK et al.	—	2021	→
An integrative analysis of 5HTT-mediated mechanism of hyperactivity to non-threatening voices.	Chen C et al.	—	2020	→
Annual Research Review: Rethinking childhood trauma-new research directions for measurement, study design and analytical strategies.	Danese A	—	2020	→
Asenapine in the Treatment of Bipolar Depression.	El-Mallakh RS et al.	—	2020	→
Association between resilience and a functional polymorphism in the serotonin transporter (SLC6A4) gene: A meta-analysis.	González-Giraldo Y et al.	—	2020	→
Association of FKBP5 genotype with depressive symptoms in patients with coronary heart disease: a prospective study.	Brandt J et al.	—	2020	→
Catechol-<i>O</i>-methyltransferase <i>Val<sup>158</sup>Met</i> Genotype and Early-Life Family Adversity Interactively Affect Attention-Deficit Hyperactivity Symptoms Across Childhood.	Abraham E et al.	—	2020	→
Cortico-limbic functional connectivity mediates the effect of early life stress on suicidality in bipolar depressed 5-HTTLPR*s carriers.	Vai B et al.	—	2020	→
Effects of stress on functional connectivity during verbal processing.	Nair N et al.	—	2020	→
Enrichment Environment Positively Influences Depression- and Anxiety-Like Behavior in Serotonin Transporter Knockout Rats through the Modulation of Neuroplasticity, Spine, and GABAergic Markers.	Sbrini G et al.	—	2020	→
Hypersensitivity to amphetamine's psychomotor and reinforcing effects in serotonin transporter knockout rats: Glutamate in the nucleus accumbens.	Caffino L et al.	—	2020	→
Influence of psychosocial stress on activation in human brain regions: moderation by the 5-HTTLPR genetic locus.	Sun X et al.	—	2020	→
Interaction Between the 5-Hydroxytryptamine Transporter-Linked Polymorphic Region (5-HTTLPR) and Negative Life Events in Adolescent Heavy Drinking.	Kim J et al.	—	2020	→
Interactions of the GABRG2 polymorphisms and childhood trauma on suicide attempt and related traits in depressed patients.	Yin H et al.	—	2020	→
Interpersonal childhood adversity and stress generation in adolescence: Moderation by HPA axis multilocus genetic variation.	Huang M et al.	—	2020	→
Maternal neglect and the serotonin system are associated with daytime sleep in infant rhesus monkeys.	Baxter A et al.	—	2020	→
Metabolic, Molecular, and Behavioral Effects of Western Diet in Serotonin Transporter-Deficient Mice: Rescue by Heterozygosity?	Veniaminova E et al.	—	2020	→
Neonatal Tactile Stimulation Alters Behaviors in Heterozygous Serotonin Transporter Male Rats: Role of the Amygdala.	Roversi K et al.	—	2020	→
Recent Stressful Life Events (SLE) and Adolescent Mental Health: Initial Validation of the LEIA, a New Checklist for SLE Assessment According to Their Severity, Interpersonal, and Dependent Nature.	Moya-Higueras J et al.	—	2020	→
The influence of stress and early life adversity on addiction: Psychobiological mechanisms of risk and resilience.	al'Absi M	—	2020	→
The influence of temperament on stress-induced emotional eating in children.	Ohrt TK et al.	—	2020	→
The Taboo Against Explicit Causal Inference in Nonexperimental Psychology.	Grosz MP et al.	—	2020	→
Translational Studies in the Complex Role of Neurotransmitter Systems in Anxiety and Anxiety Disorders.	Olivier JDA et al.	—	2020	→
Ultrahigh-resolution MRI reveals structural brain differences in serotonin transporter knockout rats after sucrose and cocaine self-administration.	Karel P et al.	—	2020	→
Which Methodological Practice(s) for Psychotherapy Science? A Systematic Review and a Proposal.	Gelo OCG et al.	—	2020	→
5-HTTLPR-brain-derived neurotrophic factor (BDNF) gene interactions and early adverse life events effect on impulsivity in suicide attempters.	Jiménez-Treviño L et al.	—	2019	→
A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory.	Sengupta A et al.	—	2019	→
Advance in Stress for Depressive Disorder.	Ding Y et al.	—	2019	→
Alterations of Glutamatergic Markers in the Prefrontal Cortex of Serotonin Transporter Knockout Rats: A Developmental Timeline.	Brivio P et al.	—	2019	→
Appetitive to aversive counter-conditioning as intervention to reduce reinstatement of reward-seeking behavior: the role of the serotonin transporter.	Karel P et al.	—	2019	→
A Systematic Literature Review of Neuroimaging of Psychopathic Traits.	Johanson M et al.	—	2019	→
Blast exposure interacts with genetic variant 5HTTLPR to predict posttraumatic stress symptoms in military explosives personnel.	Taylor MK et al.	—	2019	→
Challenges in diagnosis and treatment of comorbid eating disorders and mood disorders.	DeSocio JE	—	2019	→
Child and Adolescent Depression: A Review of Theories, Evaluation Instruments, Prevention Programs, and Treatments.	Bernaras E et al.	—	2019	→
Childhood adversity and parenting behavior: the role of oxytocin receptor gene polymorphisms.	Reichl C et al.	—	2019	→
Constitutive Serotonin Transporter Reduction Resembles Maternal Separation with Regard to Stress-Related Gene Expression.	Comasco E et al.	—	2019	→
Depression in sleep disturbance: A review on a bidirectional relationship, mechanisms and treatment.	Fang H et al.	—	2019	→
Differential Effects of Serotonin Transporter Genotype on Anxiety-Like Behavior and Cognitive Judgment Bias in Mice.	Krakenberg V et al.	—	2019	→
Dopamine D<sub>2L</sub> Receptor Deficiency Causes Stress Vulnerability through 5-HT<sub>1A</sub> Receptor Dysfunction in Serotonergic Neurons.	Shioda N et al.	—	2019	→
Effects of Conditioned Pain Modulation on the Nociceptive Flexion Reflex in Healthy People: A Systematic Review.	Dhondt E et al.	—	2019	→
Enhanced discriminative aversive learning and amygdala responsivity in 5-HT transporter mutant mice.	Lima J et al.	—	2019	→
Flotillin-1 interacts with the serotonin transporter and modulates chronic corticosterone response.	Reisinger SN et al.	—	2019	→
Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigm	Albert PR et al.	—	2019	→
Genetics of Resilience: Gene-by-Environment Interaction Studies as a Tool to Dissect Mechanisms of Resilience.	Elbau IG et al.	—	2019	→
Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model.	Ni G et al.	—	2019	→
HPA-axis multilocus genetic variation moderates associations between environmental stress and depressive symptoms among adolescents.	Starr LR et al.	—	2019	→
Identification of a novel gene regulating amygdala-mediated fear extinction.	Gunduz-Cinar O et al.	—	2019	→
Maladaptive Coping Strategies and Neuroticism Mediate the Relationship Between 5HTT-LPR Polymorphisms and Symptoms of Anxiety in Elite Athletes.	Altamura M et al.	—	2019	→
Modification of the risk of post-traumatic stress disorder (PTSD) by the 5-HTTLPR polymorphisms after Lorca's earthquakes (Murcia, Spain).	Navarro-Mateu F et al.	—	2019	→
No Interaction Between Childhood Maltreatment and Serotonin Transporter Gene in Recurrent Major Depressive Disorder: A Clinical Sample.	Özçürümez G et al.	—	2019	→
Paradoxical effects of exercise on hippocampal plasticity and cognition in mice with a heterozygous null mutation in the serotonin transporter gene.	Rogers J et al.	—	2019	→
Periaqueductal Gray Sheds Light on Dark Areas of Psychopathology.	George DT et al.	—	2019	→
PET imaging of the mouse brain reveals a dynamic regulation of SERT density in a chronic stress model.	Reisinger SN et al.	—	2019	→
Protein Biomarkers in Major Depressive Disorder: An Update.	Woods AG et al.	—	2019	→
Reduced serotonin receptors and transporters in normal aging adults: a meta-analysis of PET and SPECT imaging studies.	Karrer TM et al.	—	2019	→
Rodent models of impaired fear extinction.	Singewald N et al.	—	2019	→
Role of Tryptophan in Microbiota-Induced Depressive-Like Behavior: Evidence From Tryptophan Depletion Study.	Lukić I et al.	—	2019	→
Romantic Partner Alcohol Misuse Interacts with <i>GABRA2</i> Genotype to Predict Frequency of Drunkenness in Young Adulthood.	Gajos JM et al.	—	2019	→
Sensory Processing Sensitivity in the context of Environmental Sensitivity: A critical review and development of research agenda.	Greven CU et al.	—	2019	→
Serotonergic innervation of the human amygdala and evolutionary implications.	Lew CH et al.	—	2019	→
Serotonin transporter deficiency alters socioemotional ultrasonic communication in rats.	Golebiowska J et al.	—	2019	→
Smoking moderates association of 5-HTTLPR and in vivo availability of serotonin transporters.	Smolka MN et al.	—	2019	→
Social Isolation Rearing Induces Neuropsychiatric Diseases: Updated Overview.	Famitafreshi H et al.	—	2019	→
Sometimes It's Good to be Short: The Serotonin Transporter Gene, Positive Parenting, and Adolescent Depression.	Little K et al.	—	2019	→
The genetics of depression: successful genome-wide association studies introduce new challenges.	Ormel J et al.	—	2019	→
Understanding the Relation Between Early-Life Adversity and Depression Symptoms: The Moderating Role of Sex and an Interleukin-1β Gene Variant.	McQuaid RJ et al.	—	2019	→
When Distress Becomes Somatic: Dementia Family Caregivers' Distress and Genetic Vulnerability to Pain and Sleep Problems.	Wilson SJ et al.	—	2019	→
White Matter Microstructure in Bipolar Disorder Is Influenced by the Interaction between a Glutamate Transporter EAAT1 Gene Variant and Early Stress.	Poletti S et al.	—	2019	→
Working memory reflects vulnerability to early life adversity as a risk factor for substance use disorder in the FKBP5 cortisol cochaperone polymorphism, rs9296158.	Lovallo WR et al.	—	2019	→
A BRIEF INTRODUCTION TO THE NEUROGENETICS OF COGNITION-EMOTION INTERACTIONS.	Scult MA et al.	—	2018	→
Adaptive developmental plasticity in rhesus macaques: the serotonin transporter gene interacts with maternal care to affect juvenile social behaviour.	Madrid JE et al.	—	2018	→
A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine.	Ruben MD et al.	—	2018	→
ADHD Symptoms in Middle Adolescence Predict Exposure to Person-Related Life Stressors in Late Adolescence in 5-HTTLPR S-allele Homozygotes.	Brinksma DM et al.	—	2018	→
Affective temperament in inflammatory bowel diseases: Another brick in the wall of differentiation.	Bieliński M et al.	—	2018	→
All for One and One for All: Mental Disorders in One Dimension.	Caspi A et al.	—	2018	→
Automatic approach-avoidance tendencies as a candidate intermediate phenotype for depression: Associations with childhood trauma and the 5-HTTLPR transporter polymorphism.	Fleurkens P et al.	—	2018	→
Childhood and Adolescent Adversity and Cardiometabolic Outcomes: A Scientific Statement From the American Heart Association.	Suglia SF et al.	—	2018	→
Childhood trauma and emotion regulation: The moderator role of BDNF Val66Met.	Bîlc MI et al.	—	2018	→
Gene × Environment Interaction in Developmental Disorders: Where Do We Stand and What's Next?	Esposito G et al.	—	2018	→
Gene-environment interaction of monoamine oxidase A in relation to antisocial behaviour: current and future directions.	Nilsson KW et al.	—	2018	→
Genetics of language and its implications on language interventions.	Sriganesh R et al.	—	2018	→
Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder.	Arnau-Soler A et al.	—	2018	→
Hypersensitivity to sertraline in the absence of hippocampal 5-HT<sub>1A</sub>R and 5-HTT gene expression changes following paternal corticosterone treatment.	Rawat A et al.	—	2018	→
IL-18 Serum Levels and Variants of the Serotonin Transporter Gene Are Related to Awareness of Emotions in Healthy Subjects: A Preliminary Study.	Sacchinelli E et al.	—	2018	→
Imaging genetics paradigms in depression research: Systematic review and meta-analysis.	Pereira LP et al.	—	2018	→
Impaired fear extinction in serotonin transporter knockout rats is associated with increased 5-hydroxymethylcytosine in the amygdala.	Shan L et al.	—	2018	→
Modulation of glucocorticoids by the serotonin transporter polymorphism: A narrative review.	Klein Gunnewiek TM et al.	—	2018	→
Negative self-referential processing is associated with genetic variation in the serotonin transporter-linked polymorphic region (5-HTTLPR): Evidence from two independent studies.	Dainer-Best J et al.	—	2018	→
On the Developmental Timing of Stress: Delineating Sex-Specific Effects of Stress across Development on Adult Behavior.	Schroeder A et al.	—	2018	→
Parental Serotonin Transporter Polymorphism (5-HTTLPR) Moderates Associations of Stress and Child Behavior With Parenting Behavior.	Morgan JE et al.	—	2018	→
Prenatal Maternal Distress: A Risk Factor for Child Anxiety?	McLean MA et al.	—	2018	→
Prevention of Early Substance Use Mediates, and Variation at SLC6A4 Moderates, SAAF Intervention Effects on OXTR Methylation.	Beach SRH et al.	—	2018	→
Psychedelics and the essential importance of context.	Carhart-Harris RL et al.	—	2018	→
Relevance of Rodent Models of Depression in Clinical Practice: Can We Overcome the Obstacles in Translational Neuropsychiatry?	Söderlund J et al.	—	2018	→
Risk Factors for Depression: An Autobiographical Review.	Hammen C	—	2018	→
Serotonin, psychedelics and psychiatry.	Carhart-Harris RL	—	2018	→
Serotonin transporter 5-HTTLPR genotype is associated with intrusion and avoidance symptoms of DSM-5 posttraumatic stress disorder (PTSD) in Chinese earthquake survivors.	Liu L et al.	—	2018	→
Serotonin transporter gene (5-HTT) rs6354 polymorphism, job-related stress, and their interaction in burnout in healthcare workers in a Chinese hospital.	Cao Z et al.	—	2018	→
Serotonin transporter polymorphism, depressive symptoms, and emotional impulsivity among advanced breast cancer patients.	Kim Y et al.	—	2018	→
Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses.	Besnard A et al.	—	2018	→
The stress-reward-mentalizing model of depression: An integrative developmental cascade approach to child and adolescent depressive disorder based on the Research Domain Criteria (RDoC) approach.	Luyten P et al.	—	2018	→
Trajectories of mental health problems in children of parents with mental health problems: results of the BELLA study.	Plass-Christl A et al.	—	2018	→
Type A monoamine oxidase and serotonin are coordinately involved in depressive disorders: from neurotransmitter imbalance to impaired neurogenesis.	Naoi M et al.	—	2018	→
Understanding the effects of education through the lens of biology.	Sokolowski HM et al.	—	2018	→
5-HTTLPR moderates the association between attention away from angry faces and prospective depression among youth.	Jenness JL et al.	—	2017	→
A Concept Analysis of Resilience Integrating Genetics.	Niitsu K et al.	—	2017	→
A dimensional approach to modeling symptoms of neuropsychiatric disorders in the marmoset monkey.	Oikonomidis L et al.	—	2017	→
Adolescent depression linked to socioeconomic status? Molecular approaches for revealing premorbid risk factors.	Uddin M et al.	—	2017	→
Adversity and children experiencing family homelessness: Implications for health.	Cutuli JJ et al.	—	2017	→
A genetic risk factor for major depression and suicidal ideation is mitigated by physical activity.	Taylor MK et al.	—	2017	→
Anxiety disorders.	Craske MG et al.	—	2017	→
Associations Between Neurotransmitter Genes and Fatigue and Energy Levels in Women After Breast Cancer Surgery.	Eshragh J et al.	—	2017	→
Associations between serotonin transporter and behavioral traits and diagnoses related to anxiety.	Talati A et al.	—	2017	→
A systematic review and secondary data analysis of the interactions between the serotonin transporter 5-HTTLPR polymorphism and environmental and psychological factors in eating disorders.	Rozenblat V et al.	—	2017	→
BDNF Val66Met polymorphism moderates the link between child maltreatment and reappraisal ability.	Miu AC et al.	—	2017	→
Catechol-O-Methyltransferase gene (val158met) polymorphisms and anxious symptoms in early childhood: The roles of hypothalamus-pituitary-adrenal axis reactivity and life stress.	Sheikh HI et al.	—	2017	→
Child Maltreatment and Risk for Psychopathology in Childhood and Adulthood.	Jaffee SR	—	2017	→
Comparison of two approaches to prevention of mental health problems in college students: Enhancing coping and executive function skills.	Bettis AH et al.	—	2017	→
Early rearing history influences oxytocin receptor epigenetic regulation in rhesus macaques.	Baker M et al.	—	2017	→
Environmental enrichment reduces innate anxiety with no effect on depression-like behaviour in mice lacking the serotonin transporter.	Rogers J et al.	—	2017	→
Evaluating Emotional and Biological Sensitivity to Maternal Behavior among Self-injuring and Depressed Adolescent Girls Using Nonlinear Dynamics.	Crowell SE et al.	—	2017	→
Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22.	Krause-Heuer AM et al.	—	2017	→
Extremely low birth weight babies grown up: Gene-environment interaction predicts internalizing problems in the third and fourth decades of life.	Lahat A et al.	—	2017	→
Family Member Deaths in Childhood Predict Systemic Inflammation in Late Life.	Norton MC et al.	—	2017	→
Father Loss and Child Telomere Length.	Mitchell C et al.	—	2017	→
Gene × Environment Interactions: From Molecular Mechanisms to Behavior.	Halldorsdottir T et al.	—	2017	→
Genetic Heterogeneity in Depressive Symptoms Following the Death of a Spouse: Polygenic Score Analysis of the U.S. Health and Retirement Study.	Domingue BW et al.	—	2017	→
Genetic predisposition toward suicidal ideation in patients with acute coronary syndrome.	Kang HJ et al.	—	2017	→
"Gestaltomics": Systems Biology Schemes for the Study of Neuropsychiatric Diseases.	Gutierrez Najera NA et al.	—	2017	→
Heightened amygdala responsiveness in s-carriers of 5-HTTLPR genetic polymorphism reflects enhanced cortical rather than subcortical inputs: An MEG study.	Luo Q et al.	—	2017	→
Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential.	Bogdan R et al.	—	2017	→
Individual differences in early adolescents' latent trait cortisol: Interaction of early adversity and 5-HTTLPR.	Chen FR et al.	—	2017	→
Interplay between children's biobehavioral plasticity and interparental relationship in the origins of internalizing problems.	Brock RL et al.	—	2017	→
Latent trajectories of adolescent antisocial behavior: Serotonin transporter linked polymorphic region (5-HTTLPR) genotype influences sensitivity to perceived parental support.	Tung I et al.	—	2017	→
Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression.	Iurescia S et al.	—	2017	→
Maternal depression and family adversity: Linked pathways to offspring depression?	Najman JM et al.	—	2017	→
Meditation in Stressed Older Adults: Improvements in self-rated mental health not paralleled by improvements in cognitive function or physiological measures.	Oken BS et al.	—	2017	→
Mental Health Care Use in Children of Parents with Mental Health Problems: Results of the BELLA Study.	Plass-Christl A et al.	—	2017	→
Meta-analysis of the interaction between serotonin transporter promoter variant, stress, and posttraumatic stress disorder.	Zhao M et al.	—	2017	→
Nature meets nurture in religious and spiritual development.	Granqvist P et al.	—	2017	→
Neuroimaging genomics in psychiatry-a translational approach.	Mufford MS et al.	—	2017	→
Neuroplasticity of selective attention: Research foundations and preliminary evidence for a gene by intervention interaction.	Isbell E et al.	—	2017	→
Parent-Child Relationships: Implementation of a Screening and Referral Program for Adolescents With Mood Disorders.	Okeoma BC	—	2017	→
Parenting and adolescents' psychological adjustment: Longitudinal moderation by adolescents' genetic sensitivity.	Stocker CM et al.	—	2017	→
Parenting intervention effects on children's externalizing behavior: the moderating role of genotype and temperament.	Overbeek G	—	2017	→
Parents with mental health problems and their children in a German population based sample: Results of the BELLA study.	Plass-Christl A et al.	—	2017	→
Plastic and immobile: Unequal intergenerational mobility by genetic sensitivity score within sibling pairs.	Rauscher E	—	2017	→
Polygenic risk for depression and the neural correlates of working memory in healthy subjects.	Yüksel D et al.	—	2017	→
Prenatal noise and restraint stress interact to alter exploratory behavior and balance in juvenile rats, and mixed stress reverses these effects.	Badache S et al.	—	2017	→
Psychiatric Pharmacogenomics: How to Integrate into Clinical Practice.	Stahl SM	—	2017	→
Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression.	Roseman L et al.	—	2017	→
Roots and routes to resilience and its role in psychotherapy: a selective, attachment-informed review.	Holmes J	—	2017	→
Serotonin transporter gene promoter methylation in peripheral cells in healthy adults: Neural correlates and tissue specificity.	Ismaylova E et al.	—	2017	→
Serotonin transporter gene (SLC6A4) polymorphism and susceptibility to a home-visiting maternal-infant attachment intervention delivered by community health workers in South Africa: Reanalysis of a randomized controlled trial.	Morgan B et al.	—	2017	→
Serotonin transporter polymorphism moderates the effects of caregiver intrusiveness on ADHD symptoms among institutionalized preschoolers.	Baptista J et al.	—	2017	→
Sex moderates the impact of birth weight on child externalizing psychopathology.	Momany AM et al.	—	2017	→
State of Early Child Development Research, Practice, and Policy for Most Vulnerable Children: A Global Perspective.	Young ME	—	2017	→
Stress Processes Linking Parent-Child Disconnection to Disease Risk in Young Adulthood: Amplification by Genotype.	Bae D et al.	—	2017	→
The effect of childhood trauma on serum BDNF in bipolar depression is modulated by the serotonin promoter genotype.	Benedetti F et al.	—	2017	→
The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood.	Li JJ et al.	—	2017	→
The interaction between 5-HTTLPR and stress exposure influences connectivity of the executive control and default mode brain networks.	van der Meer D et al.	—	2017	→
The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological complexities.	Pruessner M et al.	—	2017	→
The neural underpinnings of cognitive flexibility and their disruption in psychotic illness.	Waltz JA	—	2017	→
The Serotonin Transporter and Early Life Stress: Translational Perspectives.	Houwing DJ et al.	—	2017	→
Youth temperament, harsh parenting, and variation in the oxytocin receptor gene forecast allostatic load during emerging adulthood.	Brody GH et al.	—	2017	→
5-HTTLPR polymorphism is linked to neural mechanisms of selective attention in preschoolers from lower socioeconomic status backgrounds.	Isbell E et al.	—	2016	→
Affective temperaments play an important role in the relationship between childhood abuse and depressive symptoms in major depressive disorder.	Toda H et al.	—	2016	→
Annual Research Review: Threats to the validity of child psychiatry and psychology.	Rutter M et al.	—	2016	→
A Prospective Cohort Study of Influences on Externalizing Behaviors Across Childhood: Results From a Nurse Home Visiting Randomized Controlled Trial.	Enoch MA et al.	—	2016	→
Citation bias and selective focus on positive findings in the literature on the serotonin transporter gene (5-HTTLPR), life stress and depression.	de Vries YA et al.	—	2016	→
Culture as a mediator of gene-environment interaction: Cultural consonance, childhood adversity, a 2A serotonin receptor polymorphism, and depression in urban Brazil.	Dressler WW et al.	—	2016	→
Depression and stressful environments: identifying gaps in conceptualization and measurement.	Hammen C	—	2016	→
Depression, Stressful Life Events, and the Impact of Variation in the Serotonin Transporter: Findings from the National Longitudinal Study of Adolescent to Adult Health (Add Health).	Haberstick BC et al.	—	2016	→
Detection of gene-environment interaction in pedigree data using genome-wide genotypes.	Nivard MG et al.	—	2016	→
Differential sensitivity to the environment: contribution of cognitive biases and genes to psychological wellbeing.	Fox E et al.	—	2016	→
Differential Susceptibility of the Developing Brain to Contextual Adversity and Stress.	Boyce WT	—	2016	→
DNA methylation in peripheral tissue of schizophrenia and bipolar disorder: a systematic review.	Teroganova N et al.	—	2016	→
Early Childhood Environment and Genetic Interactions: the Diathesis for Suicidal Behavior.	Brodsky BS	—	2016	→
Early predictors of behavioural problems in pre-schoolers - a longitudinal study of constitutional and environmental main and interaction effects.	Agnafors S et al.	—	2016	→
Financial difficulties but not other types of recent negative life events show strong interactions with 5-HTTLPR genotype in the development of depressive symptoms.	Gonda X et al.	—	2016	→
Genetic heterogeneity in depressive symptoms following the death of a spouse: Polygenic score analysis of the US Health and Retirement Study	Domingue BW et al.	—	2016	—
Genetic Moderation of Stress Effects on Corticolimbic Circuitry.	Bogdan R et al.	—	2016	→
Genetics as a molecular window into recovery, its treatment, and stress responses after stroke.	Juth V et al.	—	2016	→
GENOME-WIDE ASSOCIATION STUDY (GWAS) AND GENOME-WIDE BY ENVIRONMENT INTERACTION STUDY (GWEIS) OF DEPRESSIVE SYMPTOMS IN AFRICAN AMERICAN AND HISPANIC/LATINA WOMEN.	Dunn EC et al.	—	2016	→
Identification of the inhibitory mechanism of FDA approved selective serotonin reuptake inhibitors: an insight from molecular dynamics simulation study.	Xue W et al.	—	2016	→
Increased Seasonal Variation in Serotonin Transporter Binding in Seasonal Affective Disorder.	Tyrer AE et al.	—	2016	→
Influence of interactions between genes and childhood trauma on refractoriness in psychiatric disorders.	Kim JS et al.	—	2016	→
Interaction between COMT Val(158)Met polymorphism and childhood adversity affects reward processing in adulthood.	Boecker-Schlier R et al.	—	2016	→
Interaction of CD38 Variant and Chronic Interpersonal Stress Prospectively Predicts Social Anxiety and Depression Symptoms Over Six Years.	Tabak BA et al.	—	2016	→
Interactive effects of BDNF Val66Met genotype and trauma on limbic brain anatomy in childhood.	Marusak HA et al.	—	2016	→
Interplay between stress response genes associated with attention-deficit hyperactivity disorder and brain volume.	van der Meer D et al.	—	2016	→
Is it time for immunopsychiatry in psychotic disorders?	Leboyer M et al.	—	2016	→
Neighborhood × Serotonin Transporter Linked Polymorphic Region (5-HTTLPR) interactions for substance use from ages 10 to 24 years using a harmonized data set of African American children.	Windle M et al.	—	2016	→
Neurobiological candidate endophenotypes of social anxiety disorder.	Bas-Hoogendam JM et al.	—	2016	→
Novel Primate Model of Serotonin Transporter Genetic Polymorphisms Associated with Gene Expression, Anxiety and Sensitivity to Antidepressants.	Santangelo AM et al.	—	2016	→
Opportunities and challenges of big data for the social sciences: The case of genomic data.	Liu H et al.	—	2016	→
Oxytocin and Social Sensitivity: Gene Polymorphisms in Relation to Depressive Symptoms and Suicidal Ideation.	McQuaid RJ et al.	—	2016	→
Psychosocial mechanisms of serotonin transporter's genetic polymorphism in susceptibility to major depressive disorder: mediated by trait coping styles and interacted with life events.	Wang Y et al.	—	2016	→
Sensory processing sensitivity and serotonin gene variance: Insights into mechanisms shaping environmental sensitivity.	Homberg JR et al.	—	2016	→
Serotonin and Dopamine Gene Variation and Theory of Mind Decoding Accuracy in Major Depression: A Preliminary Investigation.	Zahavi AY et al.	—	2016	→
Serotonin Transporter and COMT Polymorphisms as Independent Predictors of Health-related Quality of Life in Patients with Panic Disorder.	Kang E et al.	—	2016	→
Stress and Fear Extinction.	Maren S et al.	—	2016	→
Stressful life events moderate the relationship between genes and biased attention to emotional faces in youth.	Jenness JL et al.	—	2016	→
Stress, relationship satisfaction, and health among African American women: Genetic moderation of effects.	Lei MK et al.	—	2016	→
Studying longitudinal trajectories in animal models of psychiatric illness and their translation to the human condition.	Driscoll CA et al.	—	2016	→
Synaptic alterations associated with depression and schizophrenia: potential as a therapeutic target.	Calabrese F et al.	—	2016	→
The BDNF Val66Met Polymorphism Interacts with Maternal Parenting Influencing Adolescent Depressive Symptoms: Evidence of Differential Susceptibility Model.	Zhang L et al.	—	2016	→
The First Pilot Genome-Wide Gene-Environment Study of Depression in the Japanese Population.	Otowa T et al.	—	2016	→
The interaction of cultural consonance and a polymorphism in the 2A serotonin receptor in relation to depression in Brazil: failure to replicate previous findings.	Dressler WW et al.	—	2016	→
The need for inclusion of sex and age of onset variables in genetic association studies of obsessive-compulsive disorder: Overview.	Mattina GF et al.	—	2016	→
The translocator protein gene is associated with symptom severity and cerebral pain processing in fibromyalgia.	Kosek E et al.	—	2016	→
What is the biological reality of gene-environment interaction estimates? An assessment of bias in developmental models.	Moore SR et al.	—	2016	→
What the alcohol doctor ordered from the neuroscientist: Theragnostic biomarkers for personalized treatments.	Heilig M et al.	—	2016	→
Why is the topic of the biological embedding of experiences important for translation?	Rutter M	—	2016	→
5-HTTLPR differentially predicts brain network responses to emotional faces.	Fisher PM et al.	—	2015	→
5-HTTLPR genotype potentiates the effects of war zone stressors on the emergence of PTSD, depressive and anxiety symptoms in soldiers deployed to iraq.	Telch MJ et al.	—	2015	→
A conceptual framework for the neurobiological study of resilience.	Kalisch R et al.	—	2015	→
ADULT ANXIETY DISORDERS IN RELATION TO TRAIT ANXIETY AND PERCEIVED STRESS IN CHILDHOOD.	Mundy EA et al.	—	2015	→
Aetiological stratification as a conceptual framework for gene-by-environment interaction research in psychiatry.	van Winkel R	—	2015	→
Affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression.	Oathes DJ et al.	—	2015	→
A Hierarchical Factor Model of Executive Functions in Adolescents: Evidence of Gene-Environment Interplay.	Li JJ et al.	—	2015	→
Allelic variation at 5-HTTLPR is associated with brain morphology in a Chinese population.	Liu J et al.	—	2015	→
A Longitudinal Study of BDNF Promoter Methylation and Depression in Breast Cancer.	Kang HJ et al.	—	2015	→
A multilevel prediction of physiological response to challenge: Interactions among child maltreatment, neighborhood crime, endothelial nitric oxide synthase gene (eNOS), and GABA(A) receptor subunit alpha-6 gene (GABRA6).	Lynch M et al.	—	2015	→
An interaction between NDE1 and high birth weight increases schizophrenia susceptibility.	Wegelius A et al.	—	2015	→
Antidepressant-like effects and basal immobility depend on age and serotonin transporter genotype.	Mitchell NC et al.	—	2015	→
Association Between 5-HTTLPR Polymorphism and Tics after Treatment with Methylphenidate in Korean Children with Attention-Deficit/Hyperactivity Disorder.	Park SY et al.	—	2015	→
A systems approach to stress, stressors and resilience in humans.	Oken BS et al.	—	2015	→
Back to the future of psychopharmacology: A perspective on animal models in drug discovery.	Hendriksen H et al.	—	2015	→
Benefits of adversity?! How life history affects the behavioral profile of mice varying in serotonin transporter genotype.	Bodden C et al.	—	2015	→
Benefits of a "vulnerability gene"? A study in serotonin transporter knockout mice.	Kästner N et al.	—	2015	→
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes.	Chen L et al.	—	2015	→
Brain organic cation transporter 2 controls response and vulnerability to stress and GSK3β signaling.	Couroussé T et al.	—	2015	→
Can we observe epigenetic effects on human brain function?	Nikolova YS et al.	—	2015	→
Childhood maltreatment and stress-related psychopathology: the epigenetic memory hypothesis.	Lutz PE et al.	—	2015	→
Concurrent treatment for adolescent and parent depressed mood and suicidality: feasibility, acceptability, and preliminary findings.	Spirito A et al.	—	2015	→
Cortisol reactivity to stress among youth: stability over time and genetic variants for stress sensitivity.	Hankin BL et al.	—	2015	→
Cross-cultural gene- environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: FKBP5 polymorphisms and childhood trauma in South Asia.	Kohrt BA et al.	—	2015	→
Debating interaction: the history, and an explanation.	Tabery J	—	2015	→
Depressed patients in remission show an interaction between variance in the mineralocorticoid receptor NR3C2 gene and childhood trauma on negative memory bias.	Vrijsen JN et al.	—	2015	→
Description of relational processes: recent changes in DSM-5 and proposals for ICD-11.	Wamboldt M et al.	—	2015	→
Developmental psychopathology in an era of molecular genetics and neuroimaging: A developmental neurogenetics approach.	Hyde LW	—	2015	→
Development and the epigenome: the 'synapse' of gene-environment interplay.	Boyce WT et al.	—	2015	→
Dorsomedial Prefrontal Cortex Mediates the Impact of Serotonin Transporter Linked Polymorphic Region Genotype on Anticipatory Threat Reactions.	Klumpers F et al.	—	2015	→
Dysfunctional Attitudes and Affective Responses to Daily Stressors: Separating Cognitive, Genetic, and Clinical Influences on Stress Reactivity.	Conway CC et al.	—	2015	→
Effectiveness of the first French psychoeducational program on unipolar depression: study protocol for a randomized controlled trial.	Ducasse D et al.	—	2015	→
Effect of the 5-HTTLPR polymorphism on affective temperament, depression and body mass index in obesity.	Borkowska A et al.	—	2015	→
Effects of chronic interpersonal stress exposure on depressive symptoms are moderated by genetic variation at IL6 and IL1β in youth.	Tartter M et al.	—	2015	→
Effects of persisting emotional impact from child abuse and norepinephrine transporter genetic variation on antidepressant efficacy in major depression: a pilot study.	Singh AB et al.	—	2015	→
Epigenetics/Programming in the HPA Axis.	Buschdorf JP et al.	—	2015	→
Epigenetic variation in the serotonin transporter gene predicts resting state functional connectivity strength within the salience-network.	Muehlhan M et al.	—	2015	→
Examining gene-environment interactions in comorbid depressive and disruptive behavior disorders using a Bayesian approach.	Adrian M et al.	—	2015	→
Exposure to early life stress regulates Bdnf expression in SERT mutant rats in an anatomically selective fashion.	Calabrese F et al.	—	2015	→
Family structure instability, genetic sensitivity, and child well-being.	Mitchell C et al.	—	2015	→
Finding translation in stress research.	Hariri AR et al.	—	2015	→
FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk.	Nikolova YS et al.	—	2015	→
GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures.	Lieberman R et al.	—	2015	→
Genetic and environmental modulation of neurotrophic and anabolic stress response: Counterbalancing forces.	Taylor MK et al.	—	2015	→
Genetic Correlates of Maladaptive Beliefs: COMT VAL(158)MET and Irrational Cognitions Linked Depending on Distress.	Podina I et al.	—	2015	→
Genetic determinants of depression: recent findings and future directions.	Dunn EC et al.	—	2015	→
Genetic influences on social attention in free-ranging rhesus macaques.	Watson KK et al.	—	2015	→
Genetic moderation of interpersonal psychotherapy efficacy for low-income mothers with major depressive disorder: implications for differential susceptibility.	Cicchetti D et al.	—	2015	→
Genetic variants within the serotonin transporter associated with familial risk for major depression.	Talati A et al.	—	2015	→
I just ran a thousand analyses: benefits of multiple testing in understanding equivocal evidence on gene-environment interactions.	Heininga VE et al.	—	2015	→
Influence of life stress, 5-HTTLPR genotype, and SLC6A4 methylation on gene expression and stress response in healthy Caucasian males.	Duman EA et al.	—	2015	→
Influence of Serotonin Transporter Gene Polymorphisms and Adverse Life Events on Depressive Symptoms in the Elderly: A Population-Based Study.	Davin A et al.	—	2015	→
Inhibition of Attention for Affective Material: Contributions by <i>HOMER1</i> Gene Variation.	Wells TT et al.	—	2015	→
Interaction between SLC6A4 promoter variants and childhood trauma on the age at onset of bipolar disorders.	Etain B et al.	—	2015	→
Interaction effects between the 5-hydroxy tryptamine transporter-linked polymorphic region (5-HTTLPR) genotype and family conflict on adolescent alcohol use and misuse.	Kim J et al.	—	2015	→
Involvement of serotonin transporter gene polymorphisms (5-HTT) in impulsive behavior in the japanese population.	Nomura M et al.	—	2015	→
Is serotonin transporter polymorphism (5-HTTLPR) allele status a predictor for obsessive-compulsive disorder? A meta-analysis.	Mak L et al.	—	2015	→
Neural and genetic markers of vulnerability to post-traumatic stress symptoms among survivors of the World Trade Center attacks.	Olsson A et al.	—	2015	→
Oxytocin receptor gene variation and differential susceptibility to family environment in predicting youth borderline symptoms.	Hammen C et al.	—	2015	→
Perinatal vs genetic programming of serotonin states associated with anxiety.	Altieri SC et al.	—	2015	→
Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis.	Musliner KL et al.	—	2015	→
Serotonergic genes and depressive disorder in acute coronary syndrome: The Korean depression in ACS (K-DEPACS) study.	Kim JM et al.	—	2015	→
Serotonin transporter availability may moderate the association between perceiving stress and depressive tendencies - A SPECT with 5-HTTLPR genotyping study.	Lin SH et al.	—	2015	→
SERT and uncertainty: serotonin transporter expression influences information processing biases for ambiguous aversive cues in mice.	McHugh SB et al.	—	2015	→
Short alleles, bigger smiles? The effect of 5-HTTLPR on positive emotional expressions.	Haase CM et al.	—	2015	→
Sucrose preload reduces snacking after mild mental stress in healthy participants as a function of 5-hydroxytryptamine transporter gene promoter polymorphism.	Markus CR et al.	—	2015	→
The 5-HTTLPR confers susceptibility to anorexia nervosa in Han Chinese: evidence from a case-control and family-based study.	Chen J et al.	—	2015	→
The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia.	Yokoyama JS et al.	—	2015	→
The association between the 5-HTTLPR and neural correlates of fear conditioning and connectivity.	Klucken T et al.	—	2015	→
The hidden efficacy of interventions: gene×environment experiments from a differential susceptibility perspective.	Bakermans-Kranenburg MJ et al.	—	2015	→
The moderator effects of affective temperaments, childhood abuse and adult stressful life events on depressive symptoms in the nonclinical general adult population.	Nakai Y et al.	—	2015	→
The risk for major depression conferred by childhood maltreatment is multiplied by BDNF and SERT genetic vulnerability: a replication study.	Gutiérrez B et al.	—	2015	→
The role of prolactin in andrology: what is new?	Rastrelli G et al.	—	2015	→
The structural equation analysis of childhood abuse, adult stressful life events, and temperaments in major depressive disorders and their influence on refractoriness.	Toda H et al.	—	2015	→
Treatment-resistant depression: are animal models of depression fit for purpose?	Willner P et al.	—	2015	→
Underlying Mechanisms of Gene-Environment Interactions in Externalizing Behavior: A Systematic Review and Search for Theoretical Mechanisms.	Weeland J et al.	—	2015	→
Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors.	Juhasz G et al.	—	2015	→
Variations in central serotonergic activity - relevance of the 5-HTTLPR, life events and their interaction.	Wielpuetz C et al.	—	2015	→
White matter microstructure in bipolar disorder is influenced by the serotonin transporter gene polymorphism 5-HTTLPR.	Benedetti F et al.	—	2015	→
5-HTTLPR, anxiety and gender interaction moderates right amygdala volume in healthy subjects.	Cerasa A et al.	—	2014	→
5-HTTLPR moderates naltrexone and psychosocial treatment responses in heavy drinking men who have sex with men.	Chen AC et al.	—	2014	→
5-HTTLPR modulates the recognition accuracy and exploration of emotional facial expressions.	Boll S et al.	—	2014	→
Addiction science: Uncovering neurobiological complexity.	Volkow ND et al.	—	2014	→
Adverse childhood experiences influence white matter microstructure in patients with bipolar disorder.	Benedetti F et al.	—	2014	→
A functional variant in the neuropeptide S receptor 1 gene moderates the influence of urban upbringing on stress processing in the amygdala.	Streit F et al.	—	2014	→
A genetic variant in 12q13, a possible risk factor for bipolar disorder, is associated with depressive state, accounting for stressful life events.	Shimasaki A et al.	—	2014	→
A new life-span approach to conscientiousness and health: combining the pieces of the causal puzzle.	Friedman HS et al.	—	2014	→
Antidepressant effects on serotonin 1A/1B receptors in the rat brain using a gene x environment model.	Shrestha SS et al.	—	2014	→
Association between genes, stressful childhood events and processing bias in depression vulnerable individuals.	Vrijsen JN et al.	—	2014	→
Association between serotonin transporter genotype, brain structure and adolescent-onset major depressive disorder: a longitudinal prospective study.	Little K et al.	—	2014	→
Beating the odds: an approach to the topic of resilience in children and adolescents.	Skala K et al.	—	2014	→
Beyond classical inheritance: the influence of maternal genotype upon child's brain morphology and behavior.	van der Knaap NJ et al.	—	2014	→
Beyond genotype: serotonin transporter epigenetic modification predicts human brain function.	Nikolova YS et al.	—	2014	→
Bias in a protocol for a meta-analysis of 5-HTTLPR, stress, and depression.	Moffitt TE et al.	—	2014	→
Biomarkers in major depressive disorder: the role of mass spectrometry.	Woods AG et al.	—	2014	→
Cholesterol and the "Cycle of Violence" in attempted suicide.	Asellus P et al.	—	2014	→
Comments on Hankin BL. Adolescent depression: description, causes, and interventions. Epilepsy & behavior 2006;8:102-114.	Caplan R	—	2014	→
Daily stress reactivity and serotonin transporter gene (5-HTTLPR) variation: internalizing responses to everyday stress as a possible transdiagnostic phenotype.	Conway CC et al.	—	2014	→
Development of Ego-Resiliency: Relations to Observed Parenting and Polymorphisms in the Serotonin Transporter Gene During Early Childhood.	Taylor ZE et al.	—	2014	→
Differential impact of cumulative SES risk on methylation of protein-protein interaction pathways as a function of SLC6A4 genetic variation in African American young adults.	Beach SR et al.	—	2014	→
Differential sensitivity to prevention programming: a dopaminergic polymorphism-enhanced prevention effect on protective parenting and adolescent substance use.	Brody GH et al.	—	2014	→
Different trajectories of adolescent alcohol use: testing gene-environment interactions.	van der Zwaluw CS et al.	—	2014	→
Disentangling the molecular genetic basis of personality: from monoamines to neuropeptides.	Montag C et al.	—	2014	→
DNA methylation profiles within the serotonin transporter gene moderate the association of 5-HTTLPR and cortisol stress reactivity.	Alexander N et al.	—	2014	→
Dopamine and serotonin signaling during two sensitive developmental periods differentially impact adult aggressive and affective behaviors in mice.	Yu Q et al.	—	2014	→
Early experience affects the strength of vigilance for threat in rhesus monkey infants.	Mandalaywala TM et al.	—	2014	→
Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis.	van der Doelen RH et al.	—	2014	→
Early life stress and serotonin transporter gene variation interact to affect the transcription of the glucocorticoid and mineralocorticoid receptors, and the co-chaperone FKBP5, in the adult rat brain.	van der Doelen RH et al.	—	2014	→
Effects of genetic and early environmental risk factors for depression on serotonin transporter expression and methylation profiles.	Wankerl M et al.	—	2014	→
Emotion regulation moderates the risk associated with the 5-HTT gene and stress in children.	Ford BQ et al.	—	2014	→
Framing ethnic variations in alcohol outcomes from biological pathways to neighborhood context.	Chartier KG et al.	—	2014	→
From observational to dynamic genetics.	Haworth CM et al.	—	2014	→
Functional genetic variants in the vesicular monoamine transporter 1 modulate emotion processing.	Lohoff FW et al.	—	2014	→
Further investigation of genetics and intimate partner violence.	Stuart GL et al.	—	2014	→
Gene-environment interaction.	Manuck SB et al.	—	2014	→
Gene × environment interaction on intergroup bias: the role of 5-HTTLPR and perceived outgroup threat.	Cheon BK et al.	—	2014	→
Gene-environment interaction research in psychiatric epidemiology: a framework and implications for study design.	Belsky DW et al.	—	2014	→
Gene-environment interactions and intermediate phenotypes: early trauma and depression.	Hornung OP et al.	—	2014	→
Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism.	Zannas AS et al.	—	2014	→
Gene-environment interactions in common mental disorders: an update and strategy for a genome-wide search.	Uher R	—	2014	→
Gene-environment interactions in severe mental illness.	Uher R	—	2014	→
Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children.	Cicchetti D et al.	—	2014	→
Genetic polymorphisms and traumatic brain injury: the contribution of individual differences to recovery.	Weaver SM et al.	—	2014	→
Genetics of borderline personality disorder: systematic review and proposal of an integrative model.	Amad A et al.	—	2014	→
Glutamatergic mechanisms associated with stress-induced amygdala excitability and anxiety-related behavior.	Masneuf S et al.	—	2014	→
Harsh parenting and adolescent health: a longitudinal analysis with genetic moderation.	Brody GH et al.	—	2014	→
Hope for the best or prepare for the worst? Towards a spatial cognitive bias test for mice.	Kloke V et al.	—	2014	→
Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta-analysis.	Hosang GM et al.	—	2014	→
Is serotonin transporter genotype associated with epigenetic susceptibility or vulnerability? Examination of the impact of socioeconomic status risk on African American youth.	Beach SR et al.	—	2014	→
Lack of association between the 5-HTTLPR and positive screening for mental disorders among children exposed to urban violence and maltreatment.	Cividanes GC et al.	—	2014	→
Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders.	Bukalo O et al.	—	2014	→
Mice with compromised 5-HTT function lack phosphotyrosine-mediated inhibitory control over prefrontal 5-HT responses.	Goodfellow NM et al.	—	2014	→
Neural signatures of the interaction between the 5-HTTLPR genotype and stressful life events in healthy women.	Favaro A et al.	—	2014	→
Neurobiologic basis of craving for carbohydrates.	Ventura T et al.	—	2014	→
Neurogenetics of aggressive behavior: studies in primates.	Barr CS et al.	—	2014	→
No evidence for the association between a polymorphism in the PCLO depression candidate gene with memory bias in remitted depressed patients and healthy individuals.	Vrijsen JN et al.	—	2014	→
Nonhuman primate models of depression: effects of early experience and stress.	Worlein JM	—	2014	→
Patterns of genetic variation and the role of selection in HTR1A and HTR1B in macaques (Macaca).	Shattuck MR et al.	—	2014	→
Personality, well-being, and health.	Friedman HS et al.	—	2014	→
Prenatal stress-induced programming of genome-wide promoter DNA methylation in 5-HTT-deficient mice.	Schraut KG et al.	—	2014	→
Resistance to antidepressant drugs: the case for a more predisposition-based and less hippocampocentric research paradigm.	Willner P et al.	—	2014	→
Responsible integration of biological and psychosocial models: comments on "Genetic associations with intimate partner violence in a sample of hazardous drinking men in batterer intervention programs".	Abbey A	—	2014	→
Sensitizing effect of early adversity on depressive reactions to later proximal stress: Moderation by polymorphisms in serotonin transporter and corticotropin releasing hormone receptor genes in a 20-year longitudinal study.	Starr LR et al.	—	2014	→
Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression.	Albert PR et al.	—	2014	→
[Serotonin transporter gene and stress reactivity in unipolar depression. Role of the HPA system as endophenotype of the SLC6A4 gene].	Welper H et al.	—	2014	→
Serotonin transporter gene × environment and risk of depression in community-treated epilepsy.	Lacey CJ et al.	—	2014	→
Serotonin transporter gene methylation is associated with hippocampal gray matter volume.	Dannlowski U et al.	—	2014	→
Serotonin transporter genotype, salivary cortisol, neuroticism and life events: impact on subsequent psychopathology in healthy twins at high and low risk for affective disorder.	Vinberg M et al.	—	2014	→
Serotonin transporter-linked polymorphic region (5-HTTLPR) genotype and stressful life events interact to predict preschool-onset depression: a replication and developmental extension.	Bogdan R et al.	—	2014	→
Social subordination stress and serotonin transporter polymorphisms: associations with brain white matter tract integrity and behavior in juvenile female macaques.	Howell BR et al.	—	2014	→
Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects.	Mahar I et al.	—	2014	→
The 5-HTTLPR genotype modulates heart rate variability and its adjustment by pharmacological panic challenge in healthy men.	Agorastos A et al.	—	2014	→
The attribution of incentive salience to an appetitive conditioned cue is not affected by knockout of the serotonin transporter in rats.	Nonkes LJ et al.	—	2014	→
The effect of neighborhood disadvantage, social ties, and genetic variation on the antisocial behavior of African American women: a multilevel analysis.	Lei MK et al.	—	2014	→
The evolutionary history of SLC6A4 and the role of plasticity in Macaca.	Shattuck MR et al.	—	2014	→
The genetics of major depression.	Flint J et al.	—	2014	→
The influence of childhood abuse, adult stressful life events and temperaments on depressive symptoms in the nonclinical general adult population.	Nakai Y et al.	—	2014	→
Therapygenetics: 5-HTTLPR genotype predicts the response to exposure therapy for agoraphobia.	Knuts I et al.	—	2014	→
The serotonin-BDNF duo: developmental implications for the vulnerability to psychopathology.	Homberg JR et al.	—	2014	→
The serotonin transporter gene polymorphism 5-HTTLPR moderates the effects of stress on attention-deficit/hyperactivity disorder.	van der Meer D et al.	—	2014	→
The serotonin transporter genotype modulates the relationship between early stress and adult suicidality in bipolar disorder.	Benedetti F et al.	—	2014	→
The sociocultural appraisals, values, and emotions (SAVE) framework of prosociality: core processes from gene to meme.	Keltner D et al.	—	2014	→
Three-week bright-light intervention has dose-related effects on threat-related corticolimbic reactivity and functional coupling.	Fisher PM et al.	—	2014	→
Translating multilevel theory into multilevel research: challenges and opportunities for understanding the social determinants of psychiatric disorders.	Dunn EC et al.	—	2014	→
Variations in maternal 5-HTTLPR affect observed sensitive parenting.	Cents RA et al.	—	2014	→
Who is predisposed to insomnia: a review of familial aggregation, stress-reactivity, personality and coping style.	Harvey CJ et al.	—	2014	→
50 years of hurdles and hope in anxiolytic drug discovery.	Griebel G et al.	—	2013	→
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions.	Klengel T et al.	—	2013	→
A longitudinal study of BDNF promoter methylation and genotype with poststroke depression.	Kim JM et al.	—	2013	→
Altered inflammatory responsiveness in serotonin transporter mutant rats.	Macchi F et al.	—	2013	→
A neurogenetics approach to understanding individual differences in brain, behavior, and risk for psychopathology.	Bogdan R et al.	—	2013	→
A neurorobotic platform to test the influence of neuromodulatory signaling on anxious and curious behavior.	Krichmar JL	—	2013	→
Annual Research Review: Resilient functioning in maltreated children--past, present, and future perspectives.	Cicchetti D	—	2013	→
Antidepressant use during pregnancy and serotonin transporter genotype (SLC6A4) affect newborn serum reelin levels.	Brummelte S et al.	—	2013	→
Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity.	Murphy DL et al.	—	2013	→
A one year longitudinal study of cytokine genes and depression in breast cancer.	Kim JM et al.	—	2013	→
Association of a serotonin transporter gene polymorphism (5-HTTLPR) and stressful life events with postpartum depressive symptoms: a population-based study.	Pinheiro RT et al.	—	2013	→
Association of PER2 genotype and stressful life events with alcohol drinking in young adults.	Blomeyer D et al.	—	2013	→
A translational neuroscience framework for the development of socioemotional functioning in health and psychopathology.	Wiggins JL et al.	—	2013	→
Attention to threats and combat-related posttraumatic stress symptoms: prospective associations and moderation by the serotonin transporter gene.	Wald I et al.	—	2013	→
Bargaining models of depression and evolution of cooperation.	Rosenström T	—	2013	→
Behavior genetics: past, present, future.	Jaffee SR et al.	—	2013	→
Behavioural and neuroplastic properties of chronic lurasidone treatment in serotonin transporter knockout rats.	Luoni A et al.	—	2013	→
Beyond orchids and dandelions: testing the 5-HTT "risky" allele for evidence of phenotypic capacitance and frequency-dependent selection.	Conley D et al.	—	2013	→
Brain-derived neurotrophic factor val66met genotype and early life stress effects upon bipolar course.	Miller S et al.	—	2013	→
Candidate and non-candidate genes in behavior genetics.	Flint J et al.	—	2013	→
Child dopamine active transporter 1 genotype and parenting: evidence for evocative gene-environment correlations.	Hayden EP et al.	—	2013	→
Children's risk and resilience following a natural disaster: genetic vulnerability, posttraumatic stress, and depression.	La Greca AM et al.	—	2013	→
Combined role of childhood maltreatment, family history, and gender in the risk for alcohol dependence.	Fenton MC et al.	—	2013	→
Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder.	Moya PR et al.	—	2013	→
Comorbidities and continuities as ontogenic processes: toward a developmental spectrum model of externalizing psychopathology.	Beauchaine TP et al.	—	2013	→
COMT Val158Met modulates the effect of childhood adverse experiences on the risk of alcohol dependence.	Schellekens AF et al.	—	2013	→
Contributions of maltreatment and serotonin transporter genotype to depression in childhood, adolescence, and early adulthood.	Cutuli JJ et al.	—	2013	→
Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing.	Wellman CL et al.	—	2013	→
Cumulative socioeconomic status risk, allostatic load, and adjustment: a prospective latent profile analysis with contextual and genetic protective factors.	Brody GH et al.	—	2013	→
Depression with psychotic features is influenced by the polymorphism of the serotonin transporter gene.	Stamm TJ et al.	—	2013	→
Determinants of suicidal ideation in patients with breast cancer.	Kim JM et al.	—	2013	→
Discovering, comparing, and combining moderators of treatment on outcome after randomized clinical trials: a parametric approach.	Kraemer HC	—	2013	→
Dissociable effects of dopamine and serotonin on reversal learning.	den Ouden HE et al.	—	2013	→
Effect of acute stressor and serotonin transporter genotype on amygdala first wave transcriptome in mice.	Hohoff C et al.	—	2013	→
Environmental and familial risk factors for psychotic and non-psychotic severe depression.	Ostergaard SD et al.	—	2013	→
Epidemiology and genetics of common mental disorders in the general population: the PEGASUS-Murcia project.	Navarro-Mateu F et al.	—	2013	→
Evidence for single nucleotide polymorphisms and their association with bipolar disorder.	Szczepankiewicz A	—	2013	→
Family-based study of HTR2A in suicide attempts: observed gene, gene × environment and parent-of-origin associations.	Ben-Efraim YJ et al.	—	2013	→
Gender-specific gene-environment interaction in alcohol dependence: the impact of daily life events and GABRA2.	Perry BL et al.	—	2013	→
Gene, brains, and environment-genetic neuroimaging of depression.	Northoff G	—	2013	→
Gene-environment correlation in developmental psychopathology.	Knafo A et al.	—	2013	→
Gene-environment interaction in externalizing problems among adolescents: evidence from the Pelotas 1993 Birth Cohort Study.	Kieling C et al.	—	2013	→
Gene-environment interaction in panic disorder and posttraumatic stress disorder.	Battaglia M	—	2013	→
Gene-environment interactions in genome-wide association studies: current approaches and new directions.	Winham SJ et al.	—	2013	→
Gene-environment interactions in major depressive disorder.	Klengel T et al.	—	2013	→
Gene × environment interactions in the prediction of response to antidepressant treatment.	Klengel T et al.	—	2013	→
Genetic differential sensitivity to social environments: implications for research.	Mitchell C et al.	—	2013	→
Genetic interactions with prenatal social environment: effects on academic and behavioral outcomes.	Conley D et al.	—	2013	→
Genetic moderation of early child-care effects on social functioning across childhood: a developmental analysis.	Belsky J et al.	—	2013	→
Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder.	Power RA et al.	—	2013	→
Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: associations and gene-environment interactions with childhood/adolescent physical assault.	Sokolowski M et al.	—	2013	→
How genes and the social environment moderate each other.	Reiss D et al.	—	2013	→
Identifying genetic predictors of depression risk: 5-HTTLPR and BDNF Val66Met polymorphisms are associated with rumination and co-rumination in adolescents.	Stone LB et al.	—	2013	→
Improved cognitive flexibility in serotonin transporter knockout rats is unchanged following chronic cocaine self-administration.	Nonkes LJ et al.	—	2013	→
Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins.	Ouellet-Morin I et al.	—	2013	→
Independent effects of 5' and 3' functional variants in the serotonin transporter gene on suicidal behavior in the context of childhood trauma.	Enoch MA et al.	—	2013	→
Individual differences in neural correlates of fear conditioning as a function of 5-HTTLPR and stressful life events.	Klucken T et al.	—	2013	→
Individual differences in recovery from traumatic fear.	Holmes A et al.	—	2013	→
Influence of serotonin transporter promoter variation on the effects of separation from parent/partner on depression.	Fandiño-Losada A et al.	—	2013	→
Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorder.	Fisher HL et al.	—	2013	→
Interactive effects of corticotropin-releasing hormone receptor 1 gene and childhood adversity on depressive symptoms in young adults: findings from a longitudinal study.	Laucht M et al.	—	2013	→
Lack of serotonin transporter alters BDNF expression in the rat brain during early postnatal development.	Calabrese F et al.	—	2013	→
Longitudinal course and predictors of suicidal ideation in a rural community sample.	Handley TE et al.	—	2013	→
Longitudinal course of depressive symptoms in adulthood: linear stochastic differential equation modeling.	Rosenström T et al.	—	2013	→
Looking beyond the DNA sequence: the relevance of DNA methylation processes for the stress-diathesis model of depression.	Booij L et al.	—	2013	→
MAOA genotype, social exclusion and aggression: an experimental test of a gene-environment interaction.	Gallardo-Pujol D et al.	—	2013	→
Meta-analyses of the 5-HTTLPR polymorphisms and post-traumatic stress disorder.	Navarro-Mateu F et al.	—	2013	→
miR-15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells.	Moya PR et al.	—	2013	→
Molecular genetic gene-environment studies using candidate genes in schizophrenia: a systematic review.	Modinos G et al.	—	2013	→
Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder.	Liu Z et al.	—	2013	→
Neurogenetics of depression: a focus on reward processing and stress sensitivity.	Bogdan R et al.	—	2013	→
No interaction between serotonin transporter gene (5-HTTLPR) polymorphism and adversity on depression among Japanese children and adolescents.	Tomoda A et al.	—	2013	→
Nongenomic, glucocorticoid receptor-mediated regulation of serotonin transporter cell surface expression in embryonic stem cell derived serotonergic neurons.	Lau T et al.	—	2013	→
NOS1AP is associated with increased severity of PTSD and depression in untreated combat veterans.	Lawford BR et al.	—	2013	→
On the evolution of the serotonin transporter linked polymorphic region (5-HTTLPR) in primates.	Dobson SD et al.	—	2013	→
Opposing local effects of endocannabinoids on the activity of noradrenergic neurons and release of noradrenaline: relevance for their role in depression and in the actions of CB(1) receptor antagonists.	Kirilly E et al.	—	2013	→
Overview of Behavioral Genetics Research for Family Researchers.	Samek D et al.	—	2013	→
Paying attention to all results, positive and negative.	Duncan LE	—	2013	→
Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression.	Márquez C et al.	—	2013	→
Perseverative instrumental and Pavlovian responding to conditioned stimuli in serotonin transporter knockout rats.	Nonkes LJ et al.	—	2013	→
Physical health and incident late-life depression: modification by cytokine genes.	Kim JM et al.	—	2013	→
Population disparities in mental health: insights from cultural neuroscience.	Chiao JY et al.	—	2013	→
Positive Emotion Regulation and Psychopathology: A Transdiagnostic Cultural Neuroscience Approach.	Hechtman LA et al.	—	2013	→
Probing the association between dexamethasone-induced cortisol suppression and serotonin transporter availability among drug-free patients with major depressive disorder--a small-sample SPECT study with [¹²³I]ADAM.	Tsai HC et al.	—	2013	→
Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.	Culverhouse RC et al.	—	2013	→
Psychosocial state after bariatric surgery is associated with the serotonin-transporter promoter polymorphism.	Defrancesco M et al.	—	2013	→
Putting the 'epi' into epigenetics research in psychiatry.	El-Sayed AM et al.	—	2013	→
Reduced serotonin transporter availability decreases prefrontal control of the amygdala.	Volman I et al.	—	2013	→
Relational interventions for child maltreatment: past, present, and future perspectives.	Toth SL et al.	—	2013	→
Relationships among independent major depressions, alcohol use, and other substance use and related problems over 30 years in 397 families.	Schuckit MA et al.	—	2013	→
Resilience in shock and swim stress models of depression.	Drugan RC et al.	—	2013	→
Revisiting serotonin reuptake inhibitors and the therapeutic potential of "uptake-2" in psychiatric disorders.	Daws LC et al.	—	2013	→
Role of 5-HTTLPR polymorphism in the development of the inward/outward personality organization: a genetic association study.	Nardi B et al.	—	2013	→
Self-reported family socioeconomic status, the 5-HTTLPR genotype, and delinquent behavior in a community-based adolescent population.	Aslund C et al.	—	2013	→
Serotonin transporter length polymorphism, childhood maltreatment, and chronic depression: a specific gene-environment interaction.	Brown GW et al.	—	2013	→
SLC6 transporters: structure, function, regulation, disease association and therapeutics.	Pramod AB et al.	—	2013	→
Social, behavioral, and genetic linkages from adolescence into adulthood.	Harris KM et al.	—	2013	→
Social status moderates the relationship between facial structure and aggression.	Goetz SM et al.	—	2013	→
State dependent gene-environment interaction: serotonin transporter gene-child abuse interaction associated with suicide attempt history among depressed psychiatric inpatients.	Shinozaki G et al.	—	2013	→
Supportive family environments, genes that confer sensitivity, and allostatic load among rural African American emerging adults: a prospective analysis.	Brody GH et al.	—	2013	→
Systematic review, structural analysis, and new theoretical perspectives on the role of serotonin and associated genes in the etiology of psychopathy and sociopathy.	Yildirim BO et al.	—	2013	→
Temperament moderates associations between exposure to stress and children's externalizing problems.	Schermerhorn AC et al.	—	2013	→
Temporal factors in the extinction of fear in inbred mouse strains differing in extinction efficacy.	MacPherson K et al.	—	2013	→
The 5-HTTLPR polymorphism in the serotonin transporter gene moderates the association between emotional behavior and changes in marital satisfaction over time.	Haase CM et al.	—	2013	→
The 5-HTTLPR polymorphism is associated with altered hemodynamic responses during appetitive conditioning.	Klucken T et al.	—	2013	→
The association between physical morbidity and subtypes of severe depression.	Ostergaard SD et al.	—	2013	→
The biological and psychological basis of neuroticism: current status and future directions.	Ormel J et al.	—	2013	→
The changing understanding of the genetic and environmental causes of mental illness.	Uher R	—	2013	→
The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G × E effects.	Ray LA et al.	—	2013	→
The developmental psychopathology of irritability.	Leibenluft E et al.	—	2013	→
The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by the COMT Val¹⁵⁸Met polymorphism.	Vinkers CH et al.	—	2013	→
The effect of the serotonin transporter polymorphism (5-HTTLPR) on empathic and self-conscious emotional reactivity.	Gyurak A et al.	—	2013	→
The effects of maternal depression and maternal selective serotonin reuptake inhibitor exposure on offspring.	Olivier JD et al.	—	2013	→
The Emerging Field of Human Social Genomics.	Slavich GM et al.	—	2013	→
The Great Recession, genetic sensitivity, and maternal harsh parenting.	Lee D et al.	—	2013	→
The long-term impact of early adversity on late-life psychiatric disorders.	Gershon A et al.	—	2013	→
The neurobiological correlates of childhood adversity and implications for treatment.	Tyrka AR et al.	—	2013	→
The neurobiology of depression and antidepressant action.	Willner P et al.	—	2013	→
The neurobiology of oppositional defiant disorder and conduct disorder: altered functioning in three mental domains.	Matthys W et al.	—	2013	→
Therapygenetics: the 5HTTLPR as a biomarker for response to psychological therapy?	Bockting CL et al.	—	2013	→
Therapygenetics: Using genetic markers to predict response to psychological treatment for mood and anxiety disorders.	Lester KJ et al.	—	2013	→
The role of the serotonergic and GABA system in translational approaches in drug discovery for anxiety disorders.	Olivier JD et al.	—	2013	→
The serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cortisol stress reactivity: a meta-analysis.	Miller R et al.	—	2013	→
The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: associations with cognitive vulnerability to depression in childhood.	Hayden EP et al.	—	2013	→
The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome.	Daskalakis NP et al.	—	2013	→
The wear and tear of daily stressors on mental health.	Charles ST et al.	—	2013	→
Thresholds and perception of cold pain, heat pain, and the thermal grill illusion in patients with major depressive disorder.	Boettger MK et al.	—	2013	→
Toward an integration of cognitive and genetic models of risk for depression.	Gibb BE et al.	—	2013	→
Translating the evidence for gene association with depression into mouse models of depression-relevant behaviour: current limitations and future potential.	Pryce CR et al.	—	2013	→
Twin-based study of the complex interplay between childhood maltreatment, socioeconomic status and adult memory.	Goldberg X et al.	—	2013	→
Unexpected effects of early-life adversity and social enrichment on the anxiety profile of mice varying in serotonin transporter genotype.	Kloke V et al.	—	2013	→
Updating the mild encephalitis hypothesis of schizophrenia.	Bechter K	—	2013	→
Using genetically informed, randomized prevention trials to test etiological hypotheses about child and adolescent drug use and psychopathology.	Brody GH et al.	—	2013	→
Vulnerability to depression: a moderated mediation model of the roles of child maltreatment, peer victimization, and serotonin transporter linked polymorphic region genetic variation among children from low socioeconomic status backgrounds.	Banny AM et al.	—	2013	→
What have we learnt about the causes of ADHD?	Thapar A et al.	—	2013	→
Working conditions, serotonin transporter gene polymorphism (5-HTTLPR) and anxiety disorders: a prospective cohort study.	Liu B et al.	—	2013	→
Youth genetic vulnerability to maternal depressive symptoms: 5-HTTLPR as moderator of intergenerational transmission effects in a multiwave prospective study.	Oppenheimer CW et al.	—	2013	→
5-HTTLPR S-allele: a genetic plasticity factor regarding the effects of life events on personality?	Kuepper Y et al.	—	2012	→
5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [(11)C]SB207145 PET in humans.	Fisher PM et al.	—	2012	→
Abnormal endogenous pain modulation is a shared characteristic of many chronic pain conditions.	Staud R	—	2012	→
Acute and posttraumatic stress symptoms in a prospective gene x environment study of a university campus shooting.	Mercer KB et al.	—	2012	→
Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry.	Joeyen-Waldorf J et al.	—	2012	→
A latent modeling approach to genotype-phenotype relationships: maternal problem behavior clusters, prenatal smoking, and MAOA genotype.	McGrath LM et al.	—	2012	→
Ambulatory monitoring in the genetics of psychosomatic medicine.	Finan PH et al.	—	2012	→
A new public health genomics model for common complex diseases, with an application to common behavioral disorders.	Taneri B et al.	—	2012	→
An interaction between perceived stress and 5HTTLPR genotype in the prediction of stable depressive symptomatology.	Beaver KM et al.	—	2012	→
Association between serotonin transporter promoter polymorphisms and psychological distress in a diabetic population.	Wilhelm K et al.	—	2012	→
Association between the serotonin transporter triallelic genotype and eating problems is moderated by the experience of childhood trauma in women.	Stoltenberg SF et al.	—	2012	→
Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy.	Kenna GA et al.	—	2012	→
Associations of cytokine gene polymorphisms with post-stroke depression.	Kim JM et al.	—	2012	→
A survey of putative anxiety-associated genes in panic disorder patients with and without bladder symptoms.	Subaran RL et al.	—	2012	→
BDNF Val66Met genotype modulates the effect of childhood adversity on subgenual anterior cingulate cortex volume in healthy subjects.	Gerritsen L et al.	—	2012	→
Behavioral resilience in the post-genomic era: emerging models linking genes with environment.	Rende R	—	2012	→
Behavioural therapy based on distraction alleviates impaired fear extinction in male serotonin transporter knockout rats.	Nonkes LJ et al.	—	2012	→
Biological indicators of illness risk in offspring of bipolar parents: targeting the hypothalamic-pituitary-adrenal axis and immune system.	Duffy A et al.	—	2012	→
Cannabinoid receptor genotype moderation of the effects of childhood physical abuse on anhedonia and depression.	Agrawal A et al.	—	2012	→
Childhood trauma in multiple sclerosis: a case-control study.	Spitzer C et al.	—	2012	→
Circadian rhythmicity in serotonin transporter knockout mice.	Pang RD et al.	—	2012	→
Clustering of depression and inflammation in adolescents previously exposed to childhood adversity.	Miller GE et al.	—	2012	→
Coaction of stress and serotonin transporter genotype in predicting aggression at the transition to adulthood.	Conway CC et al.	—	2012	→
Commentary: Replication, replication, replication: the continued need to substantiate GxE effects in child psychopathology--a response to Laucht et al. (2012).	Asherson P et al.	—	2012	→
Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world.	Vrieze SI et al.	—	2012	→
Connectomic intermediate phenotypes for psychiatric disorders.	Fornito A et al.	—	2012	→
Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics.	Heim C et al.	—	2012	→
Determining gene moderation of environmental risk factors for a mental disorder: a "perfect storm" of methodological problems.	Kraemer HC	—	2012	→
Developmental influence of the serotonin transporter on the expression of npas4 and GABAergic markers: modulation by antidepressant treatment.	Guidotti G et al.	—	2012	→
Diethylstilbestrol and risk of psychiatric disorders: a critical review and new insights.	Kebir O et al.	—	2012	→
Differential serotonin transport is linked to the rh5-HTTLPR in peripheral blood cells.	Singh YS et al.	—	2012	→
Differential susceptibility in spillover between interparental conflict and maternal parenting practices: evidence for OXTR and 5-HTT genes.	Sturge-Apple ML et al.	—	2012	→
Diversity in pathways to common childhood disruptive behavior disorders.	Martel MM et al.	—	2012	→
Don't throw the bathwater in with the baby.	Lichtenstein P	—	2012	→
Dopamine-system genes, childhood abuse, and clinical manifestations in women with Bulimia-Spectrum Disorders.	Groleau P et al.	—	2012	→
Efficacy of attention bias modification using threat and appetitive stimuli: a meta-analytic review.	Beard C et al.	—	2012	→
Emerging risk factors for postpartum depression: serotonin transporter genotype and omega-3 fatty acid status.	Shapiro GD et al.	—	2012	→
Epistasis between 5-HTTLPR and ADRA2B polymorphisms influences attentional bias for emotional information in healthy volunteers.	Naudts KH et al.	—	2012	→
Etiological features of borderline personality related characteristics in a birth cohort of 12-year-old children.	Belsky DW et al.	—	2012	→
Future directions in vulnerability to depression among youth: integrating risk factors and processes across multiple levels of analysis.	Hankin BL	—	2012	→
Gene × Environment interaction and resilience: effects of child maltreatment and serotonin, corticotropin releasing hormone, dopamine, and oxytocin genes.	Cicchetti D et al.	—	2012	→
Gene × environment interaction models in psychiatric genetics.	Karg K et al.	—	2012	→
Gene × environment vulnerability factors for PTSD: the HPA-axis.	Mehta D et al.	—	2012	→
Genetic and caregiving-based contributions to infant attachment: unique associations with distress reactivity and attachment security.	Raby KL et al.	—	2012	→
Genetic and hormonal sensitivity to threat: testing a serotonin transporter genotype × testosterone interaction.	Josephs RA et al.	—	2012	→
Genetic polymorphisms influence recovery from traumatic brain injury.	Weaver SM et al.	—	2012	→
Genetic sensitivity to the caregiving context: the influence of 5httlpr and BDNF val66met on indiscriminate social behavior.	Drury SS et al.	—	2012	→
Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes.	Camp MC et al.	—	2012	→
Genetic variation in serotonin transporter function affects human fear expression indexed by fear-potentiated startle.	Klumpers F et al.	—	2012	→
Genomic sciences for developmentalists: the current state of affairs.	Grigorenko EL et al.	—	2012	→
Infant development in family context: call for a genetically informed approach.	Parade SH et al.	—	2012	→
Interaction between serotonin transporter polymorphism (5-HTTLPR) and stressful life events in adolescents' trajectories of anxious/depressed symptoms.	Petersen IT et al.	—	2012	→
Interaction of dopamine transporter (DAT1) genotype and maltreatment for ADHD: a latent class analysis.	Li JJ et al.	—	2012	→
Interactions between serotonin transporter gene haplotypes and quality of mothers' parenting predict the development of children's noncompliance.	Sulik MJ et al.	—	2012	→
Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?	Aas M et al.	—	2012	→
Life stress, the dopamine receptor gene, and emerging adult drug use trajectories: a longitudinal, multilevel, mediated moderation analysis.	Brody GH et al.	—	2012	→
Linking variability in brain chemistry and circuit function through multimodal human neuroimaging.	Fisher PM et al.	—	2012	→
Maternal prenatal smoking and offspring emotional problems: no moderating effect of maternal or child 5-HTTLPR genotype.	Geels LM et al.	—	2012	→
Maternal smoking during pregnancy and child emotional problems: the relevance of maternal and child 5-HTTLPR genotype.	Cents RA et al.	—	2012	→
Mismatch or cumulative stress: toward an integrated hypothesis of programming effects.	Nederhof E et al.	—	2012	→
Moderation of adult depression by the serotonin transporter promoter variant (5-HTTLPR), childhood abuse and adult traumatic events in a general population sample.	Grabe HJ et al.	—	2012	→
Mouse models of the 5-HTTLPR × stress risk factor for depression.	Carola V et al.	—	2012	→
Neural mechanisms underlying 5-HTTLPR-related sensitivity to acute stress.	Drabant EM et al.	—	2012	→
Neurobiology of resilience.	Russo SJ et al.	—	2012	→
Pharmacological modulation of stress-induced behavioral changes in the light/dark exploration test in male C57BL/6J mice.	Ihne JL et al.	—	2012	→
Physiological and affective reactivity to a 35% CO₂ inhalation challenge in individuals differing in the 5-HTTLPR genotype and trait neuroticism.	Verschoor E et al.	—	2012	→
Potential biomarkers in psychiatry: focus on the cholesterol system.	Woods AG et al.	—	2012	→
Prognostic factors, course, and outcome of depression among older primary care patients: the PROSPECT study.	Bogner HR et al.	—	2012	→
Quantitative and molecular genetics of ADHD.	Asherson P et al.	—	2012	→
Reduced structural connectivity of a major frontolimbic pathway in generalized anxiety disorder.	Tromp DP et al.	—	2012	→
Resilience and measured gene-environment interactions.	Kim-Cohen J et al.	—	2012	→
Resilience as a dynamic concept.	Rutter M	—	2012	→
Resting amygdala and medial prefrontal metabolism predicts functional activation of the fear extinction circuit.	Linnman C et al.	—	2012	→
Searching for genetic clues at the interface of sleep and mood.	Goel N	—	2012	→
Sensory processing sensitivity: a review in the light of the evolution of biological responsivity.	Aron EN et al.	—	2012	→
Serotonergic and BDNF genes associated with depression 1 week and 1 year after mastectomy for breast cancer.	Kim JM et al.	—	2012	→
Serotonergic modulation of conditioned fear.	Homberg JR	—	2012	→
Serotonin-1A receptor polymorphism (rs6295) associated with thermal pain perception.	Lindstedt F et al.	—	2012	→
Serotonin system gene polymorphisms are associated with impulsivity in a context dependent manner.	Stoltenberg SF et al.	—	2012	→
Serotonin transporter gene as a predictor of stress generation in depression.	Starr LR et al.	—	2012	→
Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders.	Aas M et al.	—	2012	→
Serotonin transporter gene promoter polymorphism and alexithymia.	Kano M et al.	—	2012	→
Serotonin transporter gene (SLC6A4) variations are associated with poor survival in colorectal cancer patients.	Savas S et al.	—	2012	→
Serotonin transporter gene, stress and raphe-raphe interactions: a molecular mechanism of depression.	Jasinska AJ et al.	—	2012	→
Serotonin transporter genotype differentially modulates neural responses to emotional words following tryptophan depletion in patients recovered from depression and healthy volunteers.	Roiser JP et al.	—	2012	→
Serotonin transporter knockout rats show improved strategy set-shifting and reduced latent inhibition.	Nonkes LJ et al.	—	2012	→
Serotonin transporter-linked polymorphic region (5-HTTLPR) genotype is associated with cortisol responsivity to naloxone challenge.	Stephens MA et al.	—	2012	→
Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory.	Hartley CA et al.	—	2012	→
Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression.	Fisher HL et al.	—	2012	→
Stress-sensitive neurosignalling in depression: an integrated network biology approach to candidate gene selection for genetic association analysis.	van Eekelen JA et al.	—	2012	→
Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity.	Daskalakis NP et al.	—	2012	→
The 5-HTTLPR polymorphism moderates the effect of stressful life events on drinking behavior in college students of African descent.	Kranzler HR et al.	—	2012	→
The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms.	Mehta D et al.	—	2012	→
The canid genome: behavioral geneticists' best friend?	Hall NJ et al.	—	2012	→
The effects of child maltreatment on early signs of antisocial behavior: genetic moderation by tryptophan hydroxylase, serotonin transporter, and monoamine oxidase A genes.	Cicchetti D et al.	—	2012	→
The epigenetic code in depression: implications for treatment.	Schroeder M et al.	—	2012	→
The gene in its natural habitat: the importance of gene-trait interactions.	DeYoung CG et al.	—	2012	→
The Generation R Study: a review of design, findings to date, and a study of the 5-HTTLPR by environmental interaction from fetal life onward.	Tiemeier H et al.	—	2012	→
The genetic basis of mood and anxiety disorders - changing paradigms.	Binder EB	—	2012	→
The impact of serotonin transporter (5-HTTLPR) genotype on the development of resting-state functional connectivity in children and adolescents: a preliminary report.	Wiggins JL et al.	—	2012	→
The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-analyses to test developmental hypotheses about nicotine consumption.	Vrieze SI et al.	—	2012	→
The moderating effect of alcohol-specific parental rule-setting on the relation between the dopamine D2 receptor gene (DRD2), the μ-opioid receptor gene (OPRM1) and alcohol use in young adolescents.	Pieters S et al.	—	2012	→
The need for complex ideas in anorexia nervosa: why biology, environment, and psyche all matter, why therapists make mistakes, and why clinical benchmarks are needed for managing weight correction.	Strober M et al.	—	2012	→
The neurobiology of depression in later-life: clinical, neuropsychological, neuroimaging and pathophysiological features.	Naismith SL et al.	—	2012	→
Therapygenetics: moving towards personalized psychotherapy treatment.	Beevers CG et al.	—	2012	→
The reciprocal interaction between serotonin and social behaviour.	Kiser D et al.	—	2012	→
The role of genetic variability in the SLC6A4, BDNF and GABRA6 genes in anxiety-related traits.	Arias B et al.	—	2012	→
The science of resilience: implications for the prevention and treatment of depression.	Southwick SM et al.	—	2012	→
The serotonin transporter gene and functional and pathological adaptation to environmental variation across the life span.	Homberg JR et al.	—	2012	→
The serotonin transporter gene is a substrate for age and stress dependent epigenetic regulation in rhesus macaque brain: potential roles in genetic selection and gene × environment interactions.	Lindell SG et al.	—	2012	→
The serotonin transporter gene linked polymorphic region is associated with the behavioral response to repeated stress exposure in infant rhesus macaques.	Spinelli S et al.	—	2012	→
The serotonin transporter gene polymorphism (5HTTLPR) moderates the effect of adolescent environmental conditions on self-esteem in young adulthood: a structural equation modeling approach.	Jonassaint CR et al.	—	2012	→
The stress-coping (mis)match hypothesis for nature × nurture interactions.	Homberg JR	—	2012	→
Translating epidemiology in psychiatry: the future is here.	Weissman M	—	2012	→
Treatment- and population-dependent activity patterns of behavioral and expression QTLs.	Ziebarth JD et al.	—	2012	→
Variations in the promoter region of the serotonin transporter gene and biased attention for emotional information: a meta-analysis.	Pergamin-Hight L et al.	—	2012	→
5-HT and depression: is the glass half-full?	Sharp T et al.	—	2011	→
5-HTTLPR and BDNF Val66Met polymorphisms moderate effects of stress on rumination.	Clasen PC et al.	—	2011	→
5-HTTLPR moderates the relation between changes in depressive and bulimic symptoms in adolescent girls: a longitudinal study.	Mata J et al.	—	2011	→
A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry.	Duncan LE et al.	—	2011	→
Affective and neuroendocrine stress reactivity to an academic examination: influence of the 5-HTTLPR genotype and trait neuroticism.	Verschoor E et al.	—	2011	→
All (C57BL/6) Mice are not Created Equal.	Kiselycznyk C et al.	—	2011	→
A mouse model to address unresolved antidepressant issues.	Homberg JR	—	2011	→
A new interaction between SLC6A4 variation and child abuse is associated with resting heart rate.	Shinozaki G et al.	—	2011	→
Animal model and neurobiology of suicide.	Preti A	—	2011	→
Animal models of depression and anxiety: What do they tell us about human condition?	Neumann ID et al.	—	2011	→
Animal models of human anxiety disorders: reappraisal from a developmental psychopathology vantage point.	Lampis V et al.	—	2011	→
An interaction between a neuropeptide Y gene polymorphism and early adversity modulates endocrine stress responses.	Witt SH et al.	—	2011	→
An Interdisciplinary Approach to Studying Gene-Environment Interactions: From Twin Studies to Gene Identification and Back.	Dick DM	—	2011	→
Annual Research Review: Developmental considerations of gene by environment interactions.	Lenroot RK et al.	—	2011	→
A novel BDNF polymorphism affects plasma protein levels in interaction with early adversity in rhesus macaques.	Cirulli F et al.	—	2011	→
An update on psychogenic movement disorders.	Ellenstein A et al.	—	2011	→
Association between 5-HTTLPR and Borderline Personality Disorder Traits among Youth.	Hankin BL et al.	—	2011	→
Association between a serotonin transporter promoter polymorphism (5HTTLPR) and personality disorder traits in a community sample.	Blom RM et al.	—	2011	→
Behavioral and molecular genetics of dissociation: the role of the serotonin transporter gene promoter polymorphism (5-HTTLPR).	Pieper S et al.	—	2011	→
Childhood adversity interacts separately with 5-HTTLPR and BDNF to predict lifetime depression diagnosis.	Carver CS et al.	—	2011	→
Children's 5-HTTLPR genotype moderates the link between maternal criticism and attentional biases specifically for facial displays of anger.	Gibb BE et al.	—	2011	→
Community attitudes to genetic susceptibility-based mental health interventions for healthy people in a large national sample.	Wilde A et al.	—	2011	→
Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene.	Lindstedt F et al.	—	2011	→
CSF 5-HIAA and exposure to and expression of interpersonal violence in suicide attempters.	Moberg T et al.	—	2011	→
Decreased regional gray matter volume in S' allele carriers of the 5-HTTLPR triallelic polymorphism.	Selvaraj S et al.	—	2011	→
Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences.	Claessens SE et al.	—	2011	→
Differential effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene × environment interactions.	van den Hove DL et al.	—	2011	→
Differential susceptibility in youth: evidence that 5-HTTLPR x positive parenting is associated with positive affect 'for better and worse'.	Hankin BL et al.	—	2011	→
Discovering imaging endophenotypes for major depression.	Hasler G et al.	—	2011	→
Dopamine D4 receptor and serotonin transporter gene effects on the longitudinal development of infant temperament.	Holmboe K et al.	—	2011	→
Effects of acute psychosocial stress exposure on endocrine and affective reactivity in college students differing in the 5-HTTLPR genotype and trait neuroticism.	Verschoor E et al.	—	2011	→
Environmental stress alters genetic regulation of novelty seeking in vervet monkeys.	Fairbanks LA et al.	—	2011	→
Epigenetics in Developmental Disorder: ADHD and Endophenotypes.	Archer T et al.	—	2011	→
Excess of serotonin affects neocortical pyramidal neuron migration.	Riccio O et al.	—	2011	→
Experimental models for anxiolytic drug discovery in the era of omes and omics.	Stewart A et al.	—	2011	→
Gene-environment interaction in anorexia nervosa: relevance of non-shared environment and the serotonin transporter gene.	Karwautz AF et al.	—	2011	→
Gene-environment interaction in psychological traits and disorders.	Dick DM	—	2011	→
Gene-environment interaction in the etiology of mathematical ability using SNP sets.	Docherty SJ et al.	—	2011	→
Gene-environment interactions between CRHR1 variants and physical assault in suicide attempts.	Ben-Efraim YJ et al.	—	2011	→
Gene-environment interactions: early life stress and risk for depressive and anxiety disorders.	Nugent NR et al.	—	2011	→
Gene-environment interactions in geriatric depression.	Lotrich FE	—	2011	→
Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop.	Bookman EB et al.	—	2011	→
Gene expression and methylation signatures of MAN2C1 are associated with PTSD.	Uddin M et al.	—	2011	→
Genes, environment, and individual differences in responding to treatment for depression.	Uher R	—	2011	→
Genetics in psychiatry: are the promises met?	Bondy B	—	2011	→
Genetics of emotion.	Bevilacqua L et al.	—	2011	→
Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional G×G and G×E differences in health and disease.	Murphy DL et al.	—	2011	→
Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins.	Sugawara H et al.	—	2011	→
Inside the prison black box: toward a life course importation model of inmate behavior.	Delisi M et al.	—	2011	→
Interaction of 5-HTTLPR and idiographic stressors predicts prospective depressive symptoms specifically among youth in a multiwave design.	Hankin BL et al.	—	2011	→
Interactive effects of corticotropin releasing hormone receptor 1, serotonin transporter linked polymorphic region, and child maltreatment on diurnal cortisol regulation and internalizing symptomatology.	Cicchetti D et al.	—	2011	→
Is depression an inflammatory disorder?	Raison CL et al.	—	2011	→
Life stress, 5-HTTLPR and mental disorder: findings from a 30-year longitudinal study.	Fergusson DM et al.	—	2011	→
Life stressors and 5-HTTLPR interaction in relation to midpregnancy depressive symptoms among African-American women.	Scheid JM et al.	—	2011	→
Looking on the bright side of serotonin transporter gene variation.	Homberg JR et al.	—	2011	→
Mapping functional brain activation using [14C]-iodoantipyrine in male serotonin transporter knockout mice.	Pang RD et al.	—	2011	→
Memory, autonoetic consciousness, and the self.	Markowitsch HJ et al.	—	2011	→
Mood and personality effects in healthy participants after chronic administration of sertraline.	Simmons JG et al.	—	2011	→
Neuroscience, neuroimaging and the law.	Markowitsch HJ et al.	—	2011	→
Ontogeny and regulation of the serotonin transporter: providing insights into human disorders.	Daws LC et al.	—	2011	→
Perceived discrimination, serotonin transporter linked polymorphic region status, and the development of conduct problems.	Brody GH et al.	—	2011	→
Perceived social support moderates the link between threat-related amygdala reactivity and trait anxiety.	Hyde LW et al.	—	2011	→
Perception of thermal pain and the thermal grill illusion is associated with polymorphisms in the serotonin transporter gene.	Lindstedt F et al.	—	2011	→
Personalized medicine can pave the way for the safe use of CB₁ receptor antagonists.	Lazary J et al.	—	2011	→
Pharmacogenetic approaches to the treatment of alcohol addiction.	Heilig M et al.	—	2011	→
Pharmacogenetics of antidepressant response.	Keers R et al.	—	2011	→
Pituitary glucocorticoid receptor deletion reduces vulnerability to chronic stress.	Wagner KV et al.	—	2011	→
Predicting cortisol stress responses in older individuals: influence of serotonin receptor 1A gene (HTR1A) and stressful life events.	Armbruster D et al.	—	2011	→
Psychopathology, trauma and delinquency: subtypes of aggression and their relevance for understanding young offenders.	Steiner H et al.	—	2011	→
Research review: gene-environment interaction research in youth depression - a systematic review with recommendations for future research.	Dunn EC et al.	—	2011	→
Reward-related behavioral paradigms for addiction research in the mouse: performance of common inbred strains.	Lederle L et al.	—	2011	→
Role of mother's genes and environment in postpartum depression.	Mitchell C et al.	—	2011	→
Serotonin Transporter (5-HTTLPR) Genotype and Childhood Trauma are Associated with Individual Differences in Decision Making.	Stoltenberg SF et al.	—	2011	→
Serotonin transporter gene and childhood trauma--a G × E effect on anxiety sensitivity.	Klauke B et al.	—	2011	→
Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results.	Uher R et al.	—	2011	→
Serotonin transporter gene polymorphism and psychiatric disorders: is there a link?	Margoob MA et al.	—	2011	→
Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder.	Morey RA et al.	—	2011	→
Serotonin transporter genotype (5-HTTLPR) predicts utilitarian moral judgments.	Marsh AA et al.	—	2011	→
Serotonin transporter genotype moderates the link between children's reports of overprotective parenting and their behavioral inhibition.	Burkhouse KL et al.	—	2011	→
Serotonin transporter genotype x construction stress interaction in rats.	Schipper P et al.	—	2011	→
Serotonin transporter polymorphism interacts with childhood adversity to predict aspects of impulsivity.	Carver CS et al.	—	2011	→
Social constraints, genetic vulnerability, and mental health following collective stress.	Holman EA et al.	—	2011	→
Strain-specific cognitive deficits in adult mice exposed to early life stress.	Mehta M et al.	—	2011	→
Stress controversies: post-traumatic stress disorder, hippocampal volume, gastroduodenal ulceration*.	Fink G	—	2011	→
Stressful life events at onset of obsessive-compulsive disorder are associated with a distinct clinical pattern.	Real E et al.	—	2011	→
Suicidal ideation during antidepressant treatment: do genetic predictors exist?	Perroud N	—	2011	→
The Biological Implausibility of the Nature-Nurture Dichotomy & What It Means for the Study of Infancy.	Lewkowicz DJ	—	2011	→
The clinical implications of mouse models of enhanced anxiety.	Sartori SB et al.	—	2011	→
The CREB1-BDNF-NTRK2 pathway in depression: multiple gene-cognition-environment interactions.	Juhasz G et al.	—	2011	→
The effects of allostatic load on neural systems subserving motivation, mood regulation, and social affiliation.	Beauchaine TP et al.	—	2011	→
The effects of child maltreatment and polymorphisms of the serotonin transporter and dopamine D4 receptor genes on infant attachment and intervention efficacy.	Cicchetti D et al.	—	2011	→
The end of the primary outcome measure: a research agenda for constructing its replacement.	De Los Reyes A et al.	—	2011	→
The genetic blueprint of major depressive disorder: contributions of imaging genetics studies.	Scharinger C et al.	—	2011	→
The genetics of eating disorders.	Helder SG et al.	—	2011	→
The HTR1A and HTR1B receptor genes influence stress-related information processing.	Mekli K et al.	—	2011	→
The influence of gene-environment interactions on alcohol consumption and alcohol use disorders: a comprehensive review.	Young-Wolff KC et al.	—	2011	→
The influence of psychiatric screening in healthy populations selection: a new study and meta-analysis of functional 5-HTTLPR and rs25531 polymorphisms and anxiety-related personality traits.	Minelli A et al.	—	2011	→
The other allele: exploring the long allele of the serotonin transporter gene as a potential risk factor for psychopathy: a review of the parallels in findings.	Glenn AL	—	2011	→
The role of early life stress as a predictor for alcohol and drug dependence.	Enoch MA	—	2011	→
The serotonin transporter and emotionality: risk, resilience, and new therapeutic opportunities.	Murrough JW et al.	—	2011	→
The serotonin transporter gene alters sensitivity to attention bias modification: evidence for a plasticity gene.	Fox E et al.	—	2011	→
The serotonin transporter gene polymorphism and the effect of baseline on amygdala response to emotional faces.	von dem Hagen EA et al.	—	2011	→
The Serotonin Transporter Polymorphism (5-HTTLPR) and Alcohol Problems in Heavy Drinkers: Moderation by Depressive Symptoms.	Tartter MA et al.	—	2011	→
The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation.	Karg K et al.	—	2011	→
The social environment and IL-6 in rats and humans.	Saxton KB et al.	—	2011	→
The truth about genetic variation in the serotonin transporter gene and response to stress and medication.	McGuffin P et al.	—	2011	→
The urban environment and mental disorders: Epigenetic links.	Galea S et al.	—	2011	→
The use of the zebrafish model in stress research.	Steenbergen PJ et al.	—	2011	→
Translational epidemiology in psychiatry: linking population to clinical and basic sciences.	Weissman MM et al.	—	2011	→
Translational research approach to biological and modifiable risk factors of psychosis and affective disorders.	Baune BT et al.	—	2011	→
Understanding risk for psychopathology through imaging gene-environment interactions.	Hyde LW et al.	—	2011	→
Using gene-environment interactions to target personalized treatment in mood disorder.	Klengel T et al.	—	2011	→
Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice.	Dadomo H et al.	—	2011	→
Adolescence: what do transmission, transition, and translation have to do with it?	Casey BJ et al.	—	2010	→
A longitudinal study of epigenetic variation in twins.	Wong CC et al.	—	2010	→
Childhood maltreatment, the corticotropin-releasing hormone receptor gene and adult depression in the general population.	Grabe HJ et al.	—	2010	→
Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression?	Wankerl M et al.	—	2010	→
Early institutionalization: neurobiological consequences and genetic modifiers.	Sheridan M et al.	—	2010	→
From predisposition to illness: genetically sensitive intermediate pathways to mood disorders.	Duffy A	—	2010	→
Genetically informative research on adolescent substance use: methods, findings, and challenges.	Lynskey MT et al.	—	2010	→
Genetic Thinking in the Study of Social Relationships: Five Points of Entry.	Reiss D	—	2010	→
Inflammation, sanitation, and consternation: loss of contact with coevolved, tolerogenic microorganisms and the pathophysiology and treatment of major depression.	Raison CL et al.	—	2010	→
Interaction of chronic stress with serotonin transporter and catechol-O-methyltransferase polymorphisms in predicting youth depression.	Conway CC et al.	—	2010	→
Interpretation of interactions: guide for the perplexed.	Kendler KS et al.	—	2010	→
Introduction to the Special Issue: Genetics, Personalized Medicine, and Behavioral Intervention-Can This Combination Improve Patient Care?	Reiss D	—	2010	→
Non-linear relationship between 5-HT transporter gene expression and frequency sensitivity of 5-HT signals.	Jennings KA et al.	—	2010	→
Overview of the genetics of major depressive disorder.	Lohoff FW	—	2010	→
Reconciling specific and unspecific risk factors: the interplay between theory and data.	Buitelaar JK	—	2010	→
Serotonin transporter gene-linked polymorphic region (5-HTTLPR) and diurnal cortisol: A sex by genotype interaction.	Wankerl M et al.	—	2010	→
Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability.	Mozhui K et al.	—	2010	→
Testosterone and cortisol jointly regulate dominance: evidence for a dual-hormone hypothesis.	Mehta PH et al.	—	2010	→
Theory and methods in cultural neuroscience.	Chiao JY et al.	—	2010	→
The serotonin transporter gene length polymorphism (5-HTTLPR) and life events: no evidence for an interaction effect on neuroticism and anxious depressive symptoms.	Middeldorp CM et al.	—	2010	→