ethanol consumption phenotype

Aliases

0.5 g/kg ethanol, 0.56 g/kg ethanol, 0.75 ml of ethanol per kilogram, 0.75 ml/kg ethanol, 10% (V/V) ethanol, 10% alcohol solution, 10% ethanol, 100% ethanol, 15% ethanol, 15% ethanol (v/v), 190-proof Ethanol, 2 g/kg ethanol, 20% EtOH, 20% by volume solution, 20% ethanol, 20% ethanol solution, 20% v/v ethanol in saline, 200 Proof ethanol, 25 mM ethanol, 25% ethanol w/v, 3% ethanol, 30% ethanol, 4 hours consumption, 40 mM ethanol, 400mM ethanol, 5% ethanol, 5% ethanol solution, 50 mM ethanol, 50% ethanol, 5g/kg ethanol, 6% v/v ethanol, 70% ethanol, 75 mM ethanol, 75mM ethanol, 80% ethanol, 95% ethanol, 96% ethanol, AE, AE binge ethanol, AE binge treatment, Alcohol, CIE, DA, EtOH, EtOH consumption, Ethanol, Ethanol (95%), Prenatal alcohol, absolute ethanol, acute ethanol, acute ethanol administration, adolescent binge ethanol, adolescent ethanol, alcohol, alcohol consumption, alcohol drinking, alcohol exposure, alcohol infusion, alcohol intake, alcohol vapor, alcoholic beverages, binge alcohol, binge ethanol, binge ethanol treatment, chronic EtOH exposure, chronic EtOH treatment, chronic alcohol consumption, chronic alcohol exposure, chronic alcohol ingestion, chronic ethanol, chronic ethanol administration, chronic ethanol consumption, chronic ethanol exposure, chronic intermittent ethanol, consumption in g/kg, daily ethanol intake, drinking, ethanol, ethanol administration, ethanol consumption, ethanol dosage, ethanol dose, ethanol drinking, ethanol exposure, ethanol in utero, ethanol infusion, ethanol injection 1.0 g/kg ip, ethanol intake, ethanol licking behavior, ethanol preference, ethanol self-administration, ethanol vapor, ethanol vapor exposure, ethanol vapor treatment, ethanol vapors, ethanol withdrawal, ethanol-drinking behavior, ethyl alcohol, g of ethanol, g/kg consumption, gestational ethanol, high dose ethanol, high-dose ethanol, ice-cold 100% ethanol, intake, ip alcohol injection, long-term ethanol consumption, low concentrations of ethanol, low doses of ethanol, milliliter of ethanol, oral ethanol, overall consumption of ethanol per kilogram body weight, postnatal ethanol, prenatal ethanol, prenatal ethanol exposure, reinforcing effects of ethanol, self-administration, standard drink, withdrawal

Related entities (83)

Mentioned in (790)

Papers in which this entity is mentioned.

• Safe start, a hybrid intervention to reduce alcohol exposed pregnancies: protocol for a randomized controlled trial. (2026)
• Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships. (2026)
• Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. (2026)
• Validation of the ND-PAE Diagnosis in Children with Heavy Prenatal Alcohol Exposure. (2026)
• LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development. (2025)
• Extrachromosomal DNA-Driven Oncogene Spatial Heterogeneity and Evolution in Glioblastoma. (2025)
• Control of precision grip in children with heavy prenatal alcohol exposure. (2025)
• FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. (2025)
• Trajectories of genetic risk across dimensions of alcohol use behaviors. (2025)
• Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. (2025)
• Intranasal Administration of KCNN2 Blocking Peptide Improves Deficits in Cognitive Flexibility in Mouse Model of Fetal Alcohol Spectrum Disorders. (2025)
• Multigenerational cell tracking of DNA replication and heritable DNA damage. (2025)
• Rapid brain tumor classification from sparse epigenomic data. (2025)
• Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. (2025)
• Synchronized long-read genome, methylome, epigenome and transcriptome profiling resolve a Mendelian condition. (2025)
• Alcohol Exposure May Increase Prenatal Choline Needs Through Redirection of Choline into Lipid Synthesis Rather than Methyl Donation. (2025)
• Mutations in the bone morphogenetic protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations. (2025)
• Gastrulation-stage alcohol exposure induces similar rates of craniofacial malformations in male and female C57BL/6J mice. (2024)
• Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. (2024)
• Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach. (2024)
• Global impact of unproductive splicing on human gene expression. (2024)
• Transient loss of Polycomb components induces an epigenetic cancer fate. (2024)
• Oral supplementation of choline attenuates the development of alcohol-related liver disease (ALD). (2024)
• Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder. (2024)
• Early moderate prenatal alcohol exposure and maternal diet impact offspring DNA methylation across species. (2024)
• Mutations in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations. (2024)
• Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells. (2024)
• Validation of the ND-PAE Diagnosis in Children with Heavy Prenatal Alcohol Exposure. (2024)
• Pathogenesis of Alcoholic Fatty Liver a Narrative Review. (2023)
• Untargeted and Targeted Blood Lipidomic Signature Profile of Gestational Alcohol Exposure. (2023)
• The ameliorative effects of choline on ethanol-induced cell death in the neural tube of susceptible BXD strains of mice. (2023)
• Embryonic ethanol exposure disrupts craniofacial neuromuscular integration in zebrafish larvae. (2023)
• Impact of alcohol exposure on neural development and network formation in human cortical organoids. (2023)
• Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. (2023)
• Altered dendritic morphology in dorsolateral prefrontal cortex of nonhuman primates prenatally exposed to maternal immune activation. (2023)
• Gene-alcohol interactions in birth defects. (2023)
• Racial/Ethnic Disparity in Association Between Fetal Alcohol Syndrome and Alcohol Intake During Pregnancy: Multisite Retrospective Cohort Study. (2023)
• The Collaborative Study on the Genetics of Alcoholism: Overview. (2023)
• Alcohol and Immunology: Mechanisms of multi-organ damage. Summary of the 2022 alcohol and Immunology research interest group (AIRIG) meeting. (2023)
• Screening for Alcohol Use in Pregnancy: a Review of Current Practices and Perspectives. (2023)
• High-throughput detection of craniofacial defects in fluorescent zebrafish. (2023)
• Concordance of Ethyl Glucuronide, Blood Alcohol Content, and Self-Reported Alcohol Use in Russian Women with HIV and Hepatitis C Virus Co-Infection. (2023)
• Alternative splicing events as peripheral biomarkers for motor learning deficit caused by adverse prenatal environments. (2023)
• Development and validation of a postnatal risk score that identifies children with prenatal alcohol exposure. (2022)
• Prenatal alcohol exposure contributes to negative pregnancy outcomes by altering fetal vascular dynamics and the placental transcriptome. (2022)
• The effects of gestational choline supplementation on cerebellar Purkinje cell number in the sheep model of binge alcohol exposure during the first trimester-equivalent. (2022)
• Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts. (2022)
• Prenatal alcohol exposure can be determined from baby teeth: Proof of concept. (2022)
• Untargeted Metabolome Analysis Reveals Reductions in Maternal Hepatic Glucose and Amino Acid Content That Correlate with Fetal Organ Weights in a Mouse Model of Fetal Alcohol Spectrum Disorders. (2022)
• Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling. (2022)
• Activation of the anterior cingulate cortex ameliorates anxiety in a preclinical model of fetal alcohol spectrum disorders. (2022)
• Embryonic Nicotine Exposure Disrupts Adult Social Behavior and Craniofacial Development in Zebrafish. (2022)
• The pro-apoptotic Bax gene modifies susceptibility to craniofacial dysmorphology following gastrulation-stage alcohol exposure. (2022)
• Pathogenesis of Alcohol-Associated Fatty Liver: Lessons From Transgenic Mice. (2022)
• Aging-Related Behavioral, Adiposity, and Glucose Impairments and Their Association following Prenatal Alcohol Exposure in the C57BL/6J Mouse. (2022)
• Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma. (2022)
• Evidence for long-lasting alterations in the fecal microbiota following prenatal alcohol exposure. (2022)
• Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers. (2022)
• Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. (2022)
• FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors. (2021)
• Beneficial Effects of Betaine: A Comprehensive Review. (2021)
• Cross-sectional and prospective associations of drinking characteristics with scores from the Self-Report of the Effects of Alcohol questionnaire and findings from alcohol challenges. (2021)
• Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta-analysis. (2021)
• Prenatal choline supplementation during mouse pregnancy has differential effects in alcohol-exposed fetal organs. (2021)
• Validity and Reliability of Executive Function Measures in Children With Heavy Prenatal Alcohol Exposure: Correspondence Between Multiple Raters and Laboratory Measures. (2021)
• Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. (2021)
• Prenatal Adversity Alters the Epigenetic Profile of the Prefrontal Cortex: Sexually Dimorphic Effects of Prenatal Alcohol Exposure and Food-Related Stress. (2021)
• Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. (2021)
• Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription. (2021)
• Detection of prenatal alcohol exposure using machine learning classification of resting-state functional network connectivity data. (2021)
• A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
• Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice. (2021)
• Loss of tumor protein 53 protects against alcohol-induced facial malformations in mice and zebrafish. (2021)
• Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions. (2021)
• Neurotoxic reactive astrocytes induce cell death via saturated lipids. (2021)
• Infant circulating MicroRNAs as biomarkers of effect in fetal alcohol spectrum disorders. (2021)
• Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders. (2021)
• Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway. (2021)
• Altered social recognition memory and hypothalamic neuropeptide expression in adolescent male and female rats following prenatal alcohol exposure and/or early-life adversity. (2021)
• Prenatal alcohol exposure disrupts Sonic hedgehog pathway and primary cilia genes in the mouse neural tube. (2021)
• An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder. (2021)
• Simultaneous single cell measurements of intranuclear proteins and gene expression (2021)
• Cross-Sectional Analysis of Spatial Working Memory Development in Children with Histories of Heavy Prenatal Alcohol Exposure. (2021)
• Choline metabolome response to prenatal choline supplementation across pregnancy: A randomized controlled trial. (2021)
• Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood. (2020)
• B cells and tertiary lymphoid structures promote immunotherapy response. (2020)
• Multifactorial Genetic and Environmental Hedgehog Pathway Disruption Sensitizes Embryos to Alcohol-Induced Craniofacial Defects. (2020)
• Association of Prenatal Alcohol Exposure With Psychological, Behavioral, and Neurodevelopmental Outcomes in Children From the Adolescent Brain Cognitive Development Study. (2020)
• Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex. (2020)
• Alterations in the whole brain network organization after prenatal ethanol exposure. (2020)
• Neuroprotective Peptide NAPVSIPQ Antagonizes Ethanol Inhibition of L1 Adhesion by Promoting the Dissociation of L1 and Ankyrin-G. (2020)
• Altered Maternal Plasma Fatty Acid Composition by Alcohol Consumption and Smoking during Pregnancy and Associations with Fetal Alcohol Spectrum Disorders. (2020)
• Reduced Hippocampal Volumes Partially Mediate Effects of Prenatal Alcohol Exposure on Spatial Navigation on a Virtual Water Maze Task in Children. (2020)
• ABHD4-dependent developmental anoikis safeguards the embryonic brain. (2020)
• Kcnn2 blockade reverses learning deficits in a mouse model of fetal alcohol spectrum disorders. (2020)
• Choline, Neurological Development and Brain Function: A Systematic Review Focusing on the First 1000 Days. (2020)
• Folding Keratin Gene Clusters during Skin Regional Specification. (2020)
• Transcriptome-Wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure. (2020)
• Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
• An interaction between fetal sex and placental weight and efficiency predicts intrauterine growth in response to maternal protein insufficiency and gestational exposure window in a mouse model of FASD. (2020)
• Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma. (2020)
• Novel Ethanol-Sensitive Mutants Identified in an F3 Forward Genetic Screen. (2020)
• Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. (2020)
• AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications. (2020)
• Modification of stem cell states by alcohol and acetaldehyde. (2020)
• Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome. (2020)
• Long-term spatial tracking of cells affected by environmental insults. (2020)
• Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020)
• Multivariate models of brain volume for identification of children and adolescents with fetal alcohol spectrum disorder. (2020)
• Reciprocal monoallelic expression of ASAR lncRNA genes controls replication timing of human chromosome 6. (2020)
• Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. (2020)
• Apparent thinning of human visual cortex during childhood is associated with myelination. (2019)
• Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction. (2019)
• Genetic compensation triggered by mutant mRNA degradation. (2019)
• Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders. (2019)
• Functional Connectivity and Metabolic Alterations in Medial Prefrontal Cortex in a Rat Model of Fetal Alcohol Spectrum Disorder: A Resting-State Functional Magnetic Resonance Imaging and in vivo Proton Magnetic Resonance Spectroscopy Study. (2019)
• Social behavioral phenotyping of the zebrafish casper mutant following embryonic alcohol exposure. (2019)
• Alcohol Use in Pregnancy. (2019)
• Fetal Alcohol Spectrum Disorders: A Review of the Neurobehavioral Deficits Associated With Prenatal Alcohol Exposure. (2019)
• Effects of nicotine exposure on murine mandibular development. (2019)
• Prenatal nicotine exposure induces depression‑like behavior in adolescent female rats via modulating neurosteroid in the hippocampus. (2019)
• Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. (2019)
• Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways. (2019)
• Differentially sensitive neuronal subpopulations in the central nervous system and the formation of hindbrain heterotopias in ethanol-exposed zebrafish. (2019)
• Maternal circulating miRNAs that predict infant FASD outcomes influence placental maturation. (2019)
• Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure. (2019)
• The Use of Functional Near-Infrared Spectroscopy to Differentiate Alcohol-Related Neurodevelopmental Impairment. (2019)
• Social deficits following embryonic ethanol exposure arise in post-larval zebrafish. (2019)
• Comparison of the 4-Digit Code, Canadian 2015, Australian 2016 and Hoyme 2016 fetal alcohol spectrum disorder diagnostic guidelines. (2019)
• Maternal choline supplementation mitigates alcohol-induced fetal cranio-facial abnormalities detected using an ultrasonographic examination in a sheep model. (2019)
• CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis. (2019)
• Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019)
• Transient Potassium Channels: Therapeutic Targets for Brain Disorders. (2019)
• Ethanol activates immune response in lymphoblastoid cells. (2019)
• Essential Role of Histone Methyltransferase G9a in Rapid Tolerance to the Anxiolytic Effects of Ethanol. (2019)
• Spatial Navigation in Children and Young Adults with Fetal Alcohol Spectrum Disorders. (2019)
• Forty Years of Assessing Neurodevelopmental and Behavioral Effects of Prenatal Alcohol Exposure in Infants: What Have We Learned? (2019)
• Effects of prenatal alcohol exposure on social competence: Asymmetry in play partner preference among heterogeneous triads of male and female rats. (2019)
• Prenatal Environment That Affects Neuronal Migration. (2019)
• Persistent Changes in Stress-Regulatory Genes in Pregnant Women or Children Exposed Prenatally to Alcohol. (2019)
• Alcohol metabolism contributes to brain histone acetylation. (2019)
• Elimination Characteristics of the Alcohol Biomarker Phosphatidylethanol (PEth) in Blood during Alcohol Detoxification. (2019)
• Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. (2018)
• Alcohol exposure promotes DNA methyltransferase DNMT3A upregulation through reactive oxygen species-dependent mechanisms. (2018)
• Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. (2018)
• Sequence, Structure, and Context Preferences of Human RNA Binding Proteins. (2018)
• mTORC2 in the dorsomedial striatum of mice contributes to alcohol-dependent F-Actin polymerization, structural modifications, and consumption. (2018)
• Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning. (2018)
• Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE. (2018)
• Combined Face-Brain Morphology and Associated Neurocognitive Correlates in Fetal Alcohol Spectrum Disorders. (2018)
• Implications of altered maternal cytokine concentrations on infant outcomes in children with prenatal alcohol exposure. (2018)
• Oxytocin Receptor Gene Variant Interacts with Intervention Delivery Format in Predicting Intervention Outcomes for Youth with Conduct Problems. (2018)
• DNA methylation as a predictor of fetal alcohol spectrum disorder. (2018)
• Sex Differences in Early Postnatal Microglial Colonization of the Developing Rat Hippocampus Following a Single-Day Alcohol Exposure. (2018)
• Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity. (2018)
• Positively selected enhancer elements endow osteosarcoma cells with metastatic competence. (2018)
• Knockdown of Mns1 Increases Susceptibility to Craniofacial Defects Following Gastrulation-Stage Alcohol Exposure in Mice. (2018)
• A novel method for determining sex in late term gestational mice based on the external genitalia. (2018)
• Twin study confirms virtually identical prenatal alcohol exposures can lead to markedly different fetal alcohol spectrum disorder outcomes-fetal genetics influences fetal vulnerability. (2018)
• Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues. (2018)
• Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain. (2018)
• Nanopore sequencing and assembly of a human genome with ultra-long reads. (2018)
• Neuroepigenetics and addiction. (2018)
• Interactive effects of prenatal alcohol exposure and chronic stress in adulthood on anxiety-like behavior and central stress-related receptor mRNA expression: Sex- and time-dependent effects. (2018)
• The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development. (2018)
• Regional Differences and Similarities in the Brain Transcriptome for Mice Selected for Ethanol Preference From HS-CC Founders. (2018)
• Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. (2018)
• L1 coupling to ankyrin and the spectrin-actin cytoskeleton modulates ethanol inhibition of L1 adhesion and ethanol teratogenesis. (2018)
• Activity-dependent Signaling and Epigenetic Abnormalities in Mice Exposed to Postnatal Ethanol. (2018)
• PDGFRA gene, maternal binge drinking and obstructive heart defects. (2018)
• Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication. (2018)
• Neurotrophins in the Brain: Interaction With Alcohol Exposure During Development. (2017)
• Effects of early-life adversity on immune function are mediated by prenatal environment: Role of prenatal alcohol exposure. (2017)
• Computer-Based Interventions for Problematic Alcohol Use: a Review of Systematic Reviews. (2017)
• Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017)
• Genetic studies of alcohol dependence in the context of the addiction cycle. (2017)
• The acute effect of cannabis on plasma, liver and brain ammonia dynamics, a translational study. (2017)
• Long-term behavioral change as a result of acute ethanol exposure in zebrafish: Evidence for a role for sonic hedgehog but not retinoic acid signaling. (2017)
• An ERP Study of Response Inhibition in the Auditory Domain in Children with Fetal Alcohol Spectrum Disorders. (2017)
• Effects of selection for ethanol preference on gene expression in the nucleus accumbens of HS-CC mice. (2017)
• Assembly of functionally integrated human forebrain spheroids. (2017)
• Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. (2017)
• Human Brain Abnormalities Associated With Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder. (2017)
• Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models. (2017)
• Genetic vulnerabilities to prenatal alcohol exposure: Limb defects in sonic hedgehog and GLI2 heterozygous mice. (2017)
• Orthotopic patient-derived xenografts of paediatric solid tumours. (2017)
• Postnatal choline supplementation selectively attenuates hippocampal microRNA alterations associated with developmental alcohol exposure. (2017)
• Gene-environment interactions in development and disease. (2017)
• Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans. (2017)
• Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome. (2017)
• Preaxial polydactyly following early gestational exposure to the smoothened agonist, SAG, in C57BL/6J mice. (2017)
• Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits. (2017)
• Ethanol itself is a holoprosencephaly-inducing teratogen. (2017)
• Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017)
• A method to reduce ancestry related germline false positives in tumor only somatic variant calling. (2017)
• Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling. (2017)
• The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network. (2017)
• Epigenetics studies of fetal alcohol spectrum disorder: where are we now? (2017)
• Disconnect between alcohol-induced alterations in chromatin structure and gene transcription in a mouse embryonic stem cell model of exposure. (2017)
• Choline and Working Memory Training Improve Cognitive Deficits Caused by Prenatal Exposure to Ethanol. (2017)
• Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis. (2017)
• Dietary choline levels modify the effects of prenatal alcohol exposure in rats. (2017)
• Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity. (2017)
• Prenatal alcohol exposure and prenatal stress differentially alter glucocorticoid signaling in the placenta and fetal brain. (2017)
• Prenatal ethanol exposure in mice phenocopies Cdon mutation by impeding Shh function in the etiology of optic nerve hypoplasia. (2017)
• Evidence for an immune signature of prenatal alcohol exposure in female rats. (2016)
• A Decision Tree to Identify Children Affected by Prenatal Alcohol Exposure. (2016)
• Perinatal maternal alcohol consumption and methylation of the dopamine receptor in the offspring: the Triple B study. (2016)
• Maternal choline supplementation in a sheep model of first trimester binge alcohol fails to protect against brain volume reductions in peripubertal lambs. (2016)
• The Alcohol Sensitivity Questionnaire: Evidence for Construct Validity. (2016)
• Maternal nutritional status as a contributing factor for the risk of fetal alcohol spectrum disorders. (2016)
• The Formation, Elimination, Interpretation, and Future Research Needs of Phosphatidylethanol for Research Studies and Clinical Practice. (2016)
• Mechanisms in the relation between GABRA2 and adolescent externalizing problems. (2016)
• Changes in Cannabis Potency Over the Last 2 Decades (1995-2014): Analysis of Current Data in the United States. (2016)
• Inhibition of Mammary Cancer Progression in Fetal Alcohol Exposed Rats by β-Endorphin Neurons. (2016)
• Breastfeeding and maternal alcohol use: Prevalence and effects on child outcomes and fetal alcohol spectrum disorders. (2016)
• Ethanol exposure during development reduces GABAergic/glycinergic neuron numbers and lobule volumes in the mouse cerebellar vermis. (2016)
• Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage. (2016)
• The Influence of Extrinsic Reinforcement on Children with Heavy Prenatal Alcohol Exposure. (2016)
• Developmental ethanol exposure-induced sleep fragmentation predicts adult cognitive impairment. (2016)
• The Nicotine-Evoked Locomotor Response: A Behavioral Paradigm for Toxicity Screening in Zebrafish (Danio rerio) Embryos and Eleutheroembryos Exposed to Methylmercury. (2016)
• Alcohol-Induced Developmental Origins of Adult-Onset Diseases. (2016)
• Fishing for Fetal Alcohol Spectrum Disorders: Zebrafish as a Model for Ethanol Teratogenesis. (2016)
• Association between alcohol consumption during pregnancy and risks of congenital heart defects in offspring: meta-analysis of epidemiological observational studies. (2016)
• Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure. (2016)
• Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. (2016)
• Plasma miRNA Profiles in Pregnant Women Predict Infant Outcomes following Prenatal Alcohol Exposure. (2016)
• Experience-Dependent Accumulation of N6-Methyladenosine in the Prefrontal Cortex Is Associated with Memory Processes in Mice. (2016)
• Pdgfra and Pdgfrb genetically interact during craniofacial development. (2016)
• DNA methylation signature of human fetal alcohol spectrum disorder. (2016)
• Alcohol Use During Pregnancy is Associated with Specific Alterations in MicroRNA Levels in Maternal Serum. (2016)
• Acute alcohol exposure during neurulation: Behavioral and brain structural consequences in adolescent C57BL/6J mice. (2016)
• Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis. (2016)
• Dose-dependent teratogenicity of the synthetic cannabinoid CP-55,940 in mice. (2016)
• Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. (2016)
• The role of romantic relationship status in pathways of risk for emerging adult alcohol use. (2016)
• Detecting Genomic Signatures of Natural Selection with Principal Component Analysis: Application to the 1000 Genomes Data. (2016)
• Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace. (2016)
• Adolescent Choline Supplementation Attenuates Working Memory Deficits in Rats Exposed to Alcohol During the Third Trimester Equivalent. (2016)
• The Genetics of Fetal Alcohol Spectrum Disorders. (2016)
• The Impact of Prenatal Ethanol Exposure on Neuroanatomical and Behavioral Development in Mice. (2016)
• Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016)
• Zebrafish as a Vertebrate Model System to Evaluate Effects of Environmental Toxicants on Cardiac Development and Function. (2016)
• Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. (2016)
• Acute prenatal exposure to ethanol on gestational day 12 elicits opposing deficits in social behaviors and anxiety-like behaviors in Sprague Dawley rats. (2016)
• Prenatal Alcohol Exposure and Pair Feeding Differentially Impact Puberty and Reproductive Development in Female Rats: Role of the Kisspeptin System. (2016)
• Short- and long-term effects of stress during adolescence on emotionality and HPA function of animals exposed to alcohol prenatally. (2016)
• Effects of ethanol exposure in utero on Cajal-Retzius cells in the developing cortex. (2015)
• Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. (2015)
• Maternal iron deficiency worsens the associative learning deficits and hippocampal and cerebellar losses in a rat model of fetal alcohol spectrum disorders. (2015)
• Prevalence and characteristics of fetal alcohol syndrome and partial fetal alcohol syndrome in a Rocky Mountain Region City. (2015)
• Tools and best practices for data processing in allelic expression analysis. (2015)
• Effects of Ethanol on the Cerebellum: Advances and Prospects. (2015)
• Genome-Wide DNA Methylation Profiling Reveals Epigenetic Changes in the Rat Nucleus Accumbens Associated With Cross-Generational Effects of Adolescent THC Exposure. (2015)
• CB1-receptor knockout neonatal mice are protected against ethanol-induced impairments of DNMT1, DNMT3A, and DNA methylation. (2015)
• Early maternal alcohol consumption alters hippocampal DNA methylation, gene expression and volume in a mouse model. (2015)
• CONTRAILS: A tool for rapid identification of transgene integration sites in complex, repetitive genomes using low-coverage paired-end sequencing. (2015)
• Pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. (2015)
• What is the DNA repair defect underlying Fanconi anemia? (2015)
• Visual search for feature conjunctions: an fMRI study comparing alcohol-related neurodevelopmental disorder (ARND) to ADHD. (2015)
• Exposure to Chronic Mild Stress Differentially Alters Corticotropin-Releasing Hormone and Arginine Vasopressin mRNA Expression in the Stress-Responsive Neurocircuitry of Male and Female Rats Prenatally Exposed to Alcohol. (2015)
• Impairment of social behaviour persists two years after embryonic alcohol exposure in zebrafish: A model of fetal alcohol spectrum disorders. (2015)
• What Happens When Children with Fetal Alcohol Spectrum Disorders Become Adults? (2015)
• Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. (2015)
• Third trimester-equivalent ethanol exposure increases anxiety-like behavior and glutamatergic transmission in the basolateral amygdala. (2015)
• Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. (2015)
• A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. (2015)
• Spatial reconstruction of single-cell gene expression data. (2015)
• Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood. (2015)
• Sex-related differences in auditory processing in adolescents with fetal alcohol spectrum disorder: A magnetoencephalographic study. (2015)
• Guided Internet-Based Parent Training for Challenging Behavior in Children With Fetal Alcohol Spectrum Disorder (Strongest Families FASD): Study Protocol for a Randomized Controlled Trial. (2015)
• Zebrafish retinal defects induced by ethanol exposure are rescued by retinoic acid and folic acid supplement. (2015)
• Effects of all three trimester moderate binge alcohol exposure on the foetal hippocampal formation and olfactory bulb. (2015)
• Candidate gene-environment interaction research: reflections and recommendations. (2015)
• Genomic influences on alcohol problems in a population-based sample of young adults. (2015)
• Prenatal arsenic exposure alters the programming of the glucocorticoid signaling system during embryonic development. (2015)
• BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells. (2015)
• Computed tomography assessment of peripubertal craniofacial morphology in a sheep model of binge alcohol drinking in the first trimester. (2015)
• Maternal periconceptional alcohol consumption and congenital heart defects. (2015)
• Impact of prenatal environmental stress on cortical development. (2015)
• Functional Connectivity Disruption in Neonates with Prenatal Marijuana Exposure. (2015)
• Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats. (2015)
• Analysis of crosstalk between retinoic acid and sonic hedgehog pathways following ethanol exposure in embryonic zebrafish. (2015)
• Aberrant development of post-movement beta rebound in adolescents and young adults with fetal alcohol spectrum disorders. (2015)
• Prenatal Alcohol Exposure and the Developing Immune System. (2015)
• Advances in Diagnosis and Treatment of Fetal Alcohol Spectrum Disorders: From Animal Models to Human Studies. (2015)
• Embryonic alcohol exposure impairs the dopaminergic system and social behavioral responses in adult zebrafish. (2015)
• Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms. (2015)
• Importance of genetics in fetal alcohol effects: null mutation of the nNOS gene worsens alcohol-induced cerebellar neuronal losses and behavioral deficits. (2015)
• Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis. (2015)
• Improving Recognition of Children Affected by Prenatal Alcohol Exposure: Detection of Exposure in Pediatric Care. (2015)
• Prenatal alcohol exposure alters steady-state and activated gene expression in the adult rat brain. (2015)
• Prenatal alcohol exposure alters methyl metabolism and programs serotonin transporter and glucocorticoid receptor expression in brain. (2015)
• Definition of critical periods for Hedgehog pathway antagonist-induced holoprosencephaly, cleft lip, and cleft palate. (2015)
• Hypothalamic-pituitary-adrenal axis and behavioral dysfunction following early binge-like prenatal alcohol exposure in mice. (2015)
• Low and moderate prenatal ethanol exposures of mice during gastrulation or neurulation delays neurobehavioral development. (2015)
• Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels. (2015)
• Simultaneous versus concurrent use of alcohol and cannabis in the National Alcohol Survey. (2015)
• Selective reduction of cerebral cortex GABA neurons in a late gestation model of fetal alcohol spectrum disorder. (2015)
• MiR-125b protects against ethanol-induced apoptosis in neural crest cells and mouse embryos by targeting Bak 1 and PUMA. (2015)
• Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex. (2015)
• Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology. (2015)
• A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation. (2014)
• Inappropriate feeding behaviors and dietary intakes in children with fetal alcohol spectrum disorder or probable prenatal alcohol exposure. (2014)
• Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation. (2014)
• Modulation of pilocarpine-induced seizures by cannabinoid receptor 1. (2014)
• Evaluation of the influence of alcohol dehydrogenase polymorphisms on alcohol elimination rates in African Americans. (2014)
• Strain dependent neurochemical changes induced by embryonic alcohol exposure in zebrafish. (2014)
• Use of alcohol before suicide in the United States. (2014)
• Commentary: catching a conserved mechanism of ethanol teratogenicity. (2014)
• MicroRNA-29b regulates ethanol-induced neuronal apoptosis in the developing cerebellum through SP1/RAX/PKR cascade. (2014)
• Condensins are Required for Maintenance of Nuclear Architecture. (2014)
• Effect of lipid raft disruption on ethanol inhibition of l1 adhesion. (2014)
• Prenatal ethanol exposure impairs executive function in mice into adulthood. (2014)
• Detecting ultralow-frequency mutations by Duplex Sequencing. (2014)
• GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics. (2014)
• An atlas of active enhancers across human cell types and tissues. (2014)
• Prenatal alcohol exposure modifies glucocorticoid receptor subcellular distribution in the medial prefrontal cortex and impairs frontal cortex-dependent learning. (2014)
• A screen of zebrafish mutants identifies ethanol-sensitive genetic loci. (2014)
• Neurocircuitry underlying stress and emotional regulation in animals prenatally exposed to alcohol and subjected to chronic mild stress in adulthood. (2014)
• Dissecting impulsivity and its relationships to drug addictions. (2014)
• Ethanol and cocaine: environmental place conditioning, stereotypy, and synergism in planarians. (2014)
• Correspondence of parent report and laboratory measures of inattention and hyperactivity in children with heavy prenatal alcohol exposure. (2014)
• Pre-administration of G9a/GLP inhibitor during synaptogenesis prevents postnatal ethanol-induced LTP deficits and neurobehavioral abnormalities in adult mice. (2014)
• Prenatal alcohol exposure reduces magnetic susceptibility contrast and anisotropy in the white matter of mouse brains. (2014)
• Maternal and neonatal plasma microRNA biomarkers for fetal alcohol exposure in an ovine model. (2014)
• Protective effects of the alcohol dehydrogenase-ADH1B*3 allele on attention and behavior problems in adolescents exposed to alcohol during pregnancy. (2014)
• Administration of memantine during withdrawal mitigates overactivity and spatial learning impairments associated with neonatal alcohol exposure in rats. (2014)
• Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity? (2014)
• Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. (2014)
• Prevalence and predictors of maternal alcohol consumption in 2 regions of Ukraine. (2014)
• Gene expression signatures affected by alcohol-induced DNA methylomic deregulation in human embryonic stem cells. (2014)
• Acute exposure to ethanol on gestational day 15 affects social motivation of female offspring. (2014)
• A comparison of the prevalence of prenatal alcohol exposure obtained via maternal self-reports versus meconium testing: a systematic literature review and meta-analysis. (2014)
• Dietary intake, nutrition, and fetal alcohol spectrum disorders in the Western Cape Province of South Africa. (2014)
• Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate. (2014)
• High-throughput transcriptome sequencing identifies candidate genetic modifiers of vulnerability to fetal alcohol spectrum disorders. (2014)
• Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. (2014)
• An evolutionarily conserved mechanism of calcium-dependent neurotoxicity in a zebrafish model of fetal alcohol spectrum disorders. (2014)
• Low-dose maternal alcohol consumption: effects in the hearts of offspring in early life and adulthood. (2014)
• Supplemental choline does not attenuate the effects of neonatal ethanol administration on habituation of the heart rate orienting response in rats. (2014)
• Effects of Acute Prenatal Exposure to Ethanol on microRNA Expression are Ameliorated by Social Enrichment. (2014)
• Genomic factors that shape craniofacial outcome and neural crest vulnerability in FASD. (2014)
• Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice exposed to alcohol during pregnancy. (2014)
• A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors. (2014)
• Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. (2014)
• Neural crest development in fetal alcohol syndrome. (2014)
• Distinct neurobehavioral dysfunction based on the timing of developmental binge-like alcohol exposure. (2014)
• Fetal alcohol programming of hypothalamic proopiomelanocortin system by epigenetic mechanisms and later life vulnerability to stress. (2014)
• Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. (2014)
• Exercise and environment as an intervention for neonatal alcohol effects on hippocampal adult neurogenesis and learning. (2014)
• Neonatal alcohol impairs the context preexposure facilitation effect in juvenile rats: dose-response and post-training consolidation effects. (2014)
• Gene-ethanol interactions underlying fetal alcohol spectrum disorders. (2014)
• Genome-wide association discoveries of alcohol dependence. (2014)
• Molecular pathways underpinning ethanol-induced neurodegeneration. (2014)
• A broadly conserved g-protein-coupled receptor kinase phosphorylation mechanism controls Drosophila smoothened activity. (2014)
• Differences between abstinent and non-abstinent individuals in recovery from alcohol use disorders. (2014)
• Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
• Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms. (2014)
• Effects of state cigarette excise taxes and smoke-free air policies on state per capita alcohol consumption in the United States, 1980 to 2009. (2014)
• Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study. (2014)
• MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells. (2014)
• The validity of phosphatidylethanol in dried blood spots of newborns for the identification of prenatal alcohol exposure. (2014)
• Baths salts, spice, and related designer drugs: the science behind the headlines. (2014)
• Gabapentin treatment for alcohol dependence: a randomized clinical trial. (2014)
• Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice. (2014)
• A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors. (2014)
• Effects of prenatal alcohol exposure and attention-deficit/hyperactivity disorder on adaptive functioning. (2014)
• The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse. (2014)
• Effects of L-glutamine supplementation on maternal and fetal hemodynamics in gestating ewes exposed to alcohol. (2014)
• Developmental age strengthens barriers to ethanol accumulation in zebrafish. (2014)
• Increased cigarette tax is associated with reductions in alcohol consumption in a longitudinal U.S. sample. (2014)
• The role of NADPH oxidase in a mouse model of fetal alcohol syndrome. (2014)
• Prenatal alcohol exposure is associated with altered subcellular distribution of glucocorticoid and mineralocorticoid receptors in the adolescent mouse hippocampal formation. (2014)
• Effects of one- and three-day binge alcohol exposure in neonatal C57BL/6 mice on spatial learning and memory in adolescence and adulthood. (2014)
• Renal dysfunction in fetal alcohol syndrome: a potential contributor on developmental disabilities of offspring. (2014)
• Choline partially prevents the impact of ethanol on the lipid raft dependent functions of l1 cell adhesion molecule. (2014)
• Embryo transfers between C57BL/6J and DBA/2J mice: Examination of a maternal effect on ethanol teratogenesis. (2014)
• Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics. (2014)
• Embryonic alcohol exposure impairs associative learning performance in adult zebrafish. (2014)
• Further development of a neurobehavioral profile of fetal alcohol spectrum disorders. (2013)
• Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in β-endorphin-producing POMC neurons of the hypothalamus. (2013)
• Alcohol modulates expression of DNA methyltranferases and methyl CpG-/CpG domain-binding proteins in murine embryonic fibroblasts. (2013)
• Effect of prenatal alcohol exposure on bony craniofacial development: a mouse MicroCT study. (2013)
• Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure. (2013)
• Maternal factors predicting cognitive and behavioral characteristics of children with fetal alcohol spectrum disorders. (2013)
• Ethanol alters gene expression and cell organization during optic vesicle evagination. (2013)
• Fate analysis of adult hippocampal progenitors in a murine model of fetal alcohol spectrum disorder (FASD). (2013)
• Association of PER2 genotype and stressful life events with alcohol drinking in young adults. (2013)
• Mitogen-activated protein kinase modulates ethanol inhibition of cell adhesion mediated by the L1 neural cell adhesion molecule. (2013)
• Impact of low dose prenatal ethanol exposure on glucose homeostasis in Sprague-Dawley rats aged up to eight months. (2013)
• Prenatal alcohol exposure and offspring cognition and school performance. A 'Mendelian randomization' natural experiment. (2013)
• Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure. (2013)
• Low dose prenatal ethanol exposure induces anxiety-like behaviour and alters dendritic morphology in the basolateral amygdala of rat offspring. (2013)
• Diffusion MRI of the developing cerebral cortical gray matter can be used to detect abnormalities in tissue microstructure associated with fetal ethanol exposure. (2013)
• The role of cortisol in chronic binge alcohol-induced cerebellar injury: Ovine model. (2013)
• Cyclic adenosine monophosphate and brain-derived neurotrophic factor decreased oxidative stress and apoptosis in developing hypothalamic neuronal cells: role of microglia. (2013)
• Alcohol metabolism and epigenetics changes. (2013)
• Effect of predictive cuing on response inhibition in children with heavy prenatal alcohol exposure. (2013)
• Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects. (2013)
• Aberrant histone deacetylase2-mediated histone modifications and synaptic plasticity in the amygdala predisposes to anxiety and alcoholism. (2013)
• G9a-mediated histone methylation regulates ethanol-induced neurodegeneration in the neonatal mouse brain. (2013)
• Effects of early postnatal alcohol exposure on the developing retinogeniculate projections in C57BL/6 mice. (2013)
• Prenatal ethanol exposure disrupts intraneocortical circuitry, cortical gene expression, and behavior in a mouse model of FASD. (2013)
• Complex cardiac defects after ethanol exposure during discrete cardiogenic events in zebrafish: prevention with folic acid. (2013)
• In utero alcohol exposure, epigenetic changes, and their consequences. (2013)
• ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice. (2013)
• A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks. (2013)
• The influence of fetal ethanol exposure on subsequent development of the cerebral cortex as revealed by magnetic resonance imaging. (2013)
• Alcohol exposure in utero increases susceptibility to prostate tumorigenesis in rat offspring. (2013)
• Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. (2013)
• Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence. (2013)
• The effects of prenatal alcohol exposure and attention-deficit/hyperactivity disorder on psychopathology and behavior. (2013)
• Longitudinal MRI reveals altered trajectory of brain development during childhood and adolescence in fetal alcohol spectrum disorders. (2013)
• Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition. (2013)
• A critical role for PDGFRα signaling in medial nasal process development. (2013)
• The feasibility and cost of neonatal screening for prenatal alcohol exposure by measuring phosphatidylethanol in dried blood spots. (2013)
• Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD. (2013)
• Acute alcohol exposure, acidemia or glutamine administration impacts amino acid homeostasis in ovine maternal and fetal plasma. (2013)
• Size does not always matter: Ts65Dn Down syndrome mice show cerebellum-dependent motor learning deficits that cannot be rescued by postnatal SAG treatment. (2013)
• Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model. (2013)
• Differences in MEG gamma oscillatory power during performance of a prosaccade task in adolescents with FASD. (2013)
• Maturation of the adolescent brain. (2013)
• Rescue of holoprosencephaly in fetal alcohol-exposed Cdon mutant mice by reduced gene dosage of Ptch1. (2013)
• Effects of alcohol on the endocrine system. (2013)
• GABRA2 markers moderate the subjective effects of alcohol. (2013)
• Cholecalciferol attenuates perseverative behavior associated with developmental alcohol exposure in rats in a dose-dependent manner. (2013)
• Impaired odor identification in children with histories of heavy prenatal alcohol exposure. (2013)
• Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus. (2013)
• Prenatal ethanol exposure delays the onset of spermatogenesis in the rat. (2013)
• Neuropsychological deficits associated with heavy prenatal alcohol exposure are not exacerbated by ADHD. (2013)
• DNA methylation program in developing hippocampus and its alteration by alcohol. (2013)
• Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders. (2013)
• Perinatal exposure to alcohol: implications for lung development and disease. (2013)
• Intrinsic properties of larval zebrafish neurons in ethanol. (2013)
• Commonality in Down and fetal alcohol syndromes. (2013)
• Basal regulation of HPA and dopamine systems is altered differentially in males and females by prenatal alcohol exposure and chronic variable stress. (2013)
• Long-lasting neural circuit dysfunction following developmental ethanol exposure. (2013)
• Association of PER2 genotype and stressful life events with alcohol drinking in young adults. (2013)
• Fetal alcohol-related growth restriction from birth through young adulthood and moderating effects of maternal prepregnancy weight. (2013)
• Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation. (2013)
• Heart field origin of great vessel precursors relies on nkx2.5-mediated vasculogenesis. (2013)
• The Genotype-Tissue Expression (GTEx) project. (2013)
• Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brain. (2013)
• Suppression and epigenetic regulation of MiR-9 contributes to ethanol teratology: evidence from zebrafish and murine fetal neural stem cell models. (2013)
• The Genotype-Tissue Expression (GTEx) project. (2013)
• Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. (2013)
• Epigenetic medicine and fetal alcohol spectrum disorders. (2013)
• Impact of combined prenatal ethanol and prenatal stress exposure on anxiety and hippocampal-sensitive learning in adult offspring. (2013)
• Different patterns of regional Purkinje cell loss in the cerebellar vermis as a function of the timing of prenatal ethanol exposure in an ovine model. (2013)
• Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice. (2013)
• Synaptic effects induced by alcohol. (2013)
• Alcohol exposure during development: Impact on the epigenome. (2013)
• Reduced expression of brain cannabinoid receptor 1 (Cnr1) is coupled with an increased complementary micro-RNA (miR-26b) in a mouse model of fetal alcohol spectrum disorders. (2013)
• Zebrafish models of human liver development and disease. (2013)
• Effects of Ethanol Exposure during Distinct Periods of Brain Development on Hippocampal Synaptic Plasticity. (2013)
• Over-expression of Nrf2 diminishes ethanol-induced oxidative stress and apoptosis in neural crest cells by inducing an antioxidant response. (2013)
• Nitric oxide rescues thalidomide mediated teratogenicity. (2012)
• Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. (2012)
• Choline supplementation mitigates trace, but not delay, eyeblink conditioning deficits in rats exposed to alcohol during development. (2012)
• Strain dependent gene expression and neurochemical levels in the brain of zebrafish: focus on a few alcohol related targets. (2012)
• Distinct spatiotemporal roles of hedgehog signalling during chick and mouse cranial base and axial skeleton development. (2012)
• Adequacy of maternal iron status protects against behavioral, neuroanatomical, and growth deficits in fetal alcohol spectrum disorders. (2012)
• Does moderate drinking harm the fetal brain? Insights from animal models. (2012)
• SOX2 hypomorphism disrupts development of the prechordal floor and optic cup. (2012)
• Opposing actions of ethanol and nicotine on microRNAs are mediated by nicotinic acetylcholine receptors in fetal cerebral cortical-derived neural progenitor cells. (2012)
• Circadian genes, the stress axis, and alcoholism. (2012)
• The effects of age at drinking onset and stressful life events on alcohol use in adulthood: a replication and extension using a population-based twin sample. (2012)
• Early exposure to alcohol leads to permanent impairment of dendritic excitability in neocortical pyramidal neurons. (2012)
• Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations. (2012)
• Housing in environmental complexity following wheel running augments survival of newly generated hippocampal neurons in a rat model of binge alcohol exposure during the third trimester equivalent. (2012)
• Selective effects of perinatal ethanol exposure in medial prefrontal cortex and nucleus accumbens. (2012)
• HDAC1 regulates fear extinction in mice. (2012)
• Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012)
• Enhanced deficits in long-term potentiation in the adult dentate gyrus with 2nd trimester ethanol consumption. (2012)
• The genetics of alcohol dependence: advancing towards systems-based approaches. (2012)
• Women's alcohol consumption and risk for alcohol-exposed pregnancies in Russia. (2012)
• Withdrawal from THC during adolescence: sex differences in locomotor activity and anxiety. (2012)
• Phosphatidylethanol (PEth) as a biomarker of alcohol consumption in HIV-positive patients in sub-Saharan Africa. (2012)
• Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. (2012)
• The majority of microRNAs detectable in serum and saliva is concentrated in exosomes. (2012)
• Alpha4 subunit-containing GABAA receptors in the accumbens shell contribute to the reinforcing effects of alcohol. (2012)
• Histone deacetylases (HDAC)-induced histone modifications in the amygdala: a role in rapid tolerance to the anxiolytic effects of ethanol. (2012)
• Comparison of spatial working memory in children with prenatal alcohol exposure and those diagnosed with ADHD; A functional magnetic resonance imaging study. (2012)
• Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012)
• Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo. (2012)
• Head circumference at birth and exposure to tobacco, alcohol and illegal drugs during early pregnancy. (2012)
• Ethanol metabolism and osmolarity modify behavioral responses to ethanol in C. elegans. (2012)
• A low concentration of ethanol impairs learning but not motor and sensory behavior in Drosophila larvae. (2012)
• Deletion of the gabra2 gene results in hypersensitivity to the acute effects of ethanol but does not alter ethanol self administration. (2012)
• A limited access mouse model of prenatal alcohol exposure that produces long-lasting deficits in hippocampal-dependent learning and memory. (2012)
• Choline supplementation and DNA methylation in the hippocampus and prefrontal cortex of rats exposed to alcohol during development. (2012)
• Lipid environment modulates the development of acute tolerance to ethanol in Caenorhabditis elegans. (2012)
• Delays in auditory processing identified in preschool children with FASD. (2012)
• miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. (2012)
• GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats. (2012)
• The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. (2012)
• The genetic basis of addictive disorders. (2012)
• Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects. (2012)
• Ethanol reduces the phase locking of neural activity in human and rodent brain. (2012)
• Prenatal alcohol exposure alters the course and severity of adjuvant-induced arthritis in female rats. (2012)
• Ethanol-induced face-brain dysmorphology patterns are correlative and exposure-stage dependent. (2012)
• The effects of perinatal choline supplementation on hippocampal cholinergic development in rats exposed to alcohol during the brain growth spurt. (2012)
• Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice. (2012)
• Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism. (2012)
• Chronic intermittent ethanol exposure and its removal induce a different miRNA expression pattern in primary cortical neuronal cultures. (2012)
• Caudate volume predicts neurocognitive performance in youth with heavy prenatal alcohol exposure. (2012)
• Ethanol exposure during pregnancy persistently attenuates cranially directed blood flow in the developing fetus: evidence from ultrasound imaging in a murine second trimester equivalent model. (2012)
• Vitamin D supplementation protects against bone loss associated with chronic alcohol administration in female mice. (2012)
• MicroRNAs control neurobehavioral development and function in zebrafish. (2012)
• Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response. (2012)
• Sleep problems in children with fetal alcohol spectrum disorders. (2012)
• Postnatal day 7 ethanol treatment causes persistent reductions in adult mouse brain volume and cortical neurons with sex specific effects on neurogenesis. (2012)
• Gene expression changes in C57BL/6J and DBA/2J mice following prenatal alcohol exposure. (2012)
• Fetal brain function in response to maternal alcohol consumption: early evidence of damage. (2012)
• A promoter polymorphism in the Per3 gene is associated with alcohol and stress response. (2012)
• Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice. (2011)
• Regulation of ethanol-sensitive EAAT2 expression through adenosine A1 receptor in astrocytes. (2011)
• Fetal alcohol exposure leads to abnormal olfactory bulb development and impaired odor discrimination in adult mice. (2011)
• The effects of prenatal alcohol exposure on behavior: rodent and primate studies. (2011)
• Alcohol alters DNA methylation patterns and inhibits neural stem cell differentiation. (2011)
• A genetic determinant of the striatal dopamine response to alcohol in men. (2011)
• Administration of memantine during ethanol withdrawal in neonatal rats: effects on long-term ethanol-induced motor incoordination and cerebellar Purkinje cell loss. (2011)
• A survey of Italian and Spanish neonatologists and paediatricians regarding awareness of the diagnosis of FAS and FASD and maternal ethanol use during pregnancy. (2011)
• Fetal alcohol spectrum disorders: experimental treatments and strategies for intervention. (2011)
• Ethanol-induced microphthalmia is not mediated by changes in retinoic acid or sonic hedgehog signaling during retinal neurogenesis. (2011)
• A Drosophila model for fetal alcohol syndrome disorders: role for the insulin pathway. (2011)
• Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. (2011)
• Two alcohol binding residues interact across a domain interface of the L1 neural cell adhesion molecule and regulate cell adhesion. (2011)
• What choline metabolism can tell us about the underlying mechanisms of fetal alcohol spectrum disorders. (2011)
• Magnetic resonance-based imaging in animal models of fetal alcohol spectrum disorder. (2011)
• Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet. (2011)
• Candidate placental biomarkers for intrauterine alcohol exposure. (2011)
• A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. (2011)
• Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies. (2011)
• Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum. (2011)
• Postmortem interval effect on RNA and gene expression in human brain tissue. (2011)
• The effects of a single memantine treatment on behavioral alterations associated with binge alcohol exposure in neonatal rats. (2011)
• Strain differences in developmental vulnerability to alcohol exposure via embryo culture in mice. (2011)
• Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. (2011)
• Effects of ethanol and NAP on cerebellar expression of the neural cell adhesion molecule L1. (2011)
• The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis. (2011)
• Ethanol causes the redistribution of L1 cell adhesion molecule in lipid rafts. (2011)
• MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. (2011)
• Focus on: epigenetics and fetal alcohol spectrum disorders. (2011)
• Ventromedian forebrain dysgenesis follows early prenatal ethanol exposure in mice. (2011)
• Does lack of multinutrient supplementation during early pregnancy increase vulnerability to alcohol-related preterm or small-for-gestational-age births? (2011)
• Agrin function associated with ocular development is a target of ethanol exposure in embryonic zebrafish. (2011)
• Effects of ethanol on physiological retinoic acid levels. (2011)
• AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II. (2011)
• Tissue plasminogen activator is required for the development of fetal alcohol syndrome in mice. (2011)
• Effects of early postnatal exposure to ethanol on retinal ganglion cell morphology and numbers of neurons in the dorsolateral geniculate in mice. (2011)
• Memory for the order of events in specific sequences: contributions of the hippocampus and medial prefrontal cortex. (2011)
• Maternal risk factors predicting child physical characteristics and dysmorphology in fetal alcohol syndrome and partial fetal alcohol syndrome. (2011)
• Up-regulation of microRNAs in brain of human alcoholics. (2011)
• Calcium-mediated repression of β-catenin and its transcriptional signaling mediates neural crest cell death in an avian model of fetal alcohol syndrome. (2011)
• Acute prenatal exposure to ethanol and social behavior: effects of age, sex, and timing of exposure. (2011)
• Local and regional network function in behaviorally relevant cortical circuits of adult mice following postnatal alcohol exposure. (2011)
• Risk factors for behavioural problems in foetal alcohol spectrum disorders. (2011)
• Large-scale analysis of acute ethanol exposure in zebrafish development: a critical time window and resilience. (2011)
• Biobehavioral markers of adverse effect in fetal alcohol spectrum disorders. (2011)
• Transcriptional and epigenetic mechanisms of addiction. (2011)
• Alteration of gene expression by alcohol exposure at early neurulation. (2011)
• Focus on: the use of animal models for the study of fetal alcohol spectrum disorders. (2011)
• Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications. (2010)
• Prenatal exposure to moderate levels of ethanol alters social behavior in adult rats: relationship to structural plasticity and immediate early gene expression in frontal cortex. (2010)
• Genome-wide scan for self-rating of the effects of alcohol in American Indians. (2010)
• Prenatal alcohol exposure: fetal programming and later life vulnerability to stress, depression and anxiety disorders. (2010)
• Prenatal alcohol exposure alters biobehavioral reactivity to pain in newborns. (2010)
• Delayed neonatal lung macrophage differentiation in a mouse model of in utero ethanol exposure. (2010)
• Alcohol during adolescence selectively alters immediate and long-term behavior and neurochemistry. (2010)
• Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta4 subunit gene promoter. (2010)
• Alcohol-induced facial dysmorphology in C57BL/6 mouse models of fetal alcohol spectrum disorder. (2010)
• Reduction of ethanol-induced ocular abnormalities in mice through dietary administration of N-acetylcysteine. (2010)
• Motor response programming and movement time in children with heavy prenatal alcohol exposure. (2010)
• Normal development of brain circuits. (2010)
• Genesis of teratogen-induced holoprosencephaly in mice. (2010)
• Histone methylation regulates memory formation. (2010)
• The molecular genetics of holoprosencephaly. (2010)
• MicroRNAs: master regulators of ethanol abuse and toxicity? (2010)
• Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. (2010)
• Fetal alcohol exposure increases mammary tumor susceptibility and alters tumor phenotype in rats. (2010)
• Genetic and epigenetic insights into fetal alcohol spectrum disorders. (2010)
• Assessment of benefits of a universal screen for maternal alcohol use during pregnancy. (2010)
• Prenatal alcohol exposure and chronic mild stress differentially alter depressive- and anxiety-like behaviors in male and female offspring. (2010)
• Consilient research approaches in studying gene x environment interactions in alcohol research. (2010)
• Fetal alcohol spectrum disorders: from research to policy. (2010)
• Prenatal alcohol exposure alters the patterns of facial asymmetry. (2010)
• ADH1B*3 and response to alcohol in African-Americans. (2010)
• Stress-induced suppression of hippocampal neurogenesis in adult male rats is altered by prenatal ethanol exposure. (2010)
• Behavioral and biological indicators of impulsivity in the development of alcohol use, problems, and disorders. (2010)
• Prenatal alcohol exposure reduces the proportion of newly produced neurons and glia in the dentate gyrus of the hippocampus in female rats. (2010)
• High-throughput caveolar proteomic signature profile for maternal binge alcohol consumption. (2010)
• Quantification of ethanol methyl (1)H magnetic resonance signal intensity following intravenous ethanol administration in primate brain. (2010)
• Distinguishing between attention-deficit hyperactivity and fetal alcohol spectrum disorders in children: clinical guidelines. (2010)
• The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. (2010)
• Conserved role of unc-79 in ethanol responses in lightweight mutant mice. (2010)
• Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. (2010)
• Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking. (2010)
• Postnatal binge-like alcohol exposure decreases dendritic complexity while increasing the density of mature spines in mPFC Layer II/III pyramidal neurons. (2010)
• Patterns of social-experience-related c-fos and Arc expression in the frontal cortices of rats exposed to saccharin or moderate levels of ethanol during prenatal brain development. (2010)
• The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos. (2010)
• Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development. (2010)
• Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. (2010)
• Gender differences in the relationship of internalizing and externalizing psychopathology to alcohol dependence: likelihood, expression and course. (2010)
• Maternal folate-related gene environment interactions and congenital heart defects. (2010)
• The relationship between self-reported drinking and BAC level in emergency room injury cases: is it a straight line? (2010)
• Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. (2010)
• Low concentrations of alcohol inhibit BDNF-dependent GABAergic plasticity via L-type Ca2+ channel inhibition in developing CA3 hippocampal pyramidal neurons. (2010)
• Chronic ethanol consumption-induced pancreatic {beta}-cell dysfunction and apoptosis through glucokinase nitration and its down-regulation. (2010)
• Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 7. (2010)
• Micro-computed tomography-based phenotypic approaches in embryology: procedural artifacts on assessments of embryonic craniofacial growth and development. (2010)
• Neurobiology of the adolescent brain and behavior: implications for substance use disorders. (2010)
• Role of microglia in ethanol's apoptotic action on hypothalamic neuronal cells in primary cultures. (2010)
• Effects of moderate drinking during pregnancy on placental gene expression. (2010)
• Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction. (2010)
• Magnetic resonance microscopy-based analyses of the brains of normal and ethanol-exposed fetal mice. (2010)
• Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model. (2010)
• Zebrafish fetal alcohol syndrome model: effects of ethanol are rescued by retinoic acid supplement. (2010)
• The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example. (2010)
• Conserved role of intragenic DNA methylation in regulating alternative promoters. (2010)
• Ethanol elevates physiological all-trans-retinoic acid levels in select loci through altering retinoid metabolism in multiple loci: a potential mechanism of ethanol toxicity. (2010)
• The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
• Prenatal exposure to drugs: effects on brain development and implications for policy and education. (2009)
• Functional CRH variation increases stress-induced alcohol consumption in primates. (2009)
• Vulnerability of macaque cranial nerve neurons to ethanol is time- and site-dependent. (2009)
• Eye abnormalities in fetal alcohol syndrome. (2009)
• The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
• Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats. (2009)
• A line of mice selected for high blood ethanol concentrations shows drinking in the dark to intoxication. (2009)
• Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation. (2009)
• Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. (2009)
• Foetal Alcohol Spectrum Disorders and alterations in brain and behaviour. (2009)
• Phosphodiesterase inhibition increases CREB phosphorylation and restores orientation selectivity in a model of fetal alcohol spectrum disorders. (2009)
• Genome-wide identification of Saccharomyces cerevisiae genes required for maximal tolerance to ethanol. (2009)
• Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol. (2009)
• Ethanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60(src). (2009)
• Paternal alcoholism, negative parenting, and the mediating role of marital satisfaction. (2009)
• Fetal exposure to ethanol has long-term effects on the severity of influenza virus infections. (2009)
• Alterations in phosphorylated cyclic adenosine monophosphate response element of binding protein activity: a pathway for fetal alcohol syndrome-related neurotoxicity. (2009)
• Ethanol teratogenesis in five inbred strains of mice. (2009)
• Ethanol induces embryonic malformations by competing for retinaldehyde dehydrogenase activity during vertebrate gastrulation. (2009)
• Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence. (2009)
• Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation. (2009)
• Choline: an essential nutrient for public health. (2009)
• Magnetic resonance spectroscopy outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders. (2009)
• Brain stress systems in the amygdala and addiction. (2009)
• Role of testosterone in mediating prenatal ethanol effects on hypothalamic-pituitary-adrenal activity in male rats. (2009)
• Blood glucose level, alcohol heavy drinking, and alcohol craving during treatment for alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) Study. (2009)
• Long-term behavioral changes in response to early developmental exposure to ethanol in zebrafish. (2009)
• Sonic hedgehog ligand partners with caveolin-1 for intracellular transport. (2009)
• Insulin-like growth factor-I mitigates motor coordination deficits associated with neonatal alcohol exposure in rats. (2009)
• Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation. (2009)
• Psychological and/or educational interventions for reducing alcohol consumption in pregnant women and women planning pregnancy. (2009)
• From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics. (2009)
• MicroCT for comparative morphology: simple staining methods allow high-contrast 3D imaging of diverse non-mineralized animal tissues. (2009)
• Developmental pathogenesis of short palpebral fissure length in children with fetal alcohol syndrome. (2009)
• Effects of prenatal ethanol exposure on hypothalamic-pituitary-adrenal function across the estrous cycle. (2009)
• Pathogenesis of holoprosencephaly. (2009)
• A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog. (2009)
• GABA A receptors: subtypes provide diversity of function and pharmacology. (2009)
• Actions and interactions of alcohol and insulin-like growth factor-1 on female pubertal development. (2009)
• Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
• Neuroimaging of children following prenatal drug exposure. (2009)
• An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. (2009)
• Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. (2009)
• Animal models of fetal alcohol spectrum disorders: impact of the social environment. (2009)
• Neuroimaging of children following prenatal drug exposure. (2009)
• Persistent deficits in heart rate response habituation following neonatal binge ethanol exposure. (2009)
• Effects of ethanol and ipsapirone on the expression of genes encoding anti-apoptotic proteins and an antioxidant enzyme in ethanol-treated neurons. (2009)
• Activity-dependent neuroprotective protein-derived peptide, NAP, preventing alcohol-induced apoptosis in fetal brain of C57BL/6 mouse. (2009)
• Altered white matter integrity in adolescent binge drinkers. (2009)
• The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. (2009)
• Magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders. (2009)
• Mechanisms of neurodegeneration and regeneration in alcoholism. (2009)
• Can prenatal ultrasound detect the effects of in-utero alcohol exposure? A pilot study. (2009)
• Genome-wide association study of alcohol dependence. (2009)
• In utero ethanol exposure impairs defenses against experimental group B streptococcus in the term Guinea pig lung. (2009)
• The embryonic preoptic area is a novel source of cortical GABAergic interneurons. (2009)
• Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8. (2009)
• Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease. (2009)
• Protein kinases and addiction. (2008)
• Alterations in ethyl alcohol pharmacokinetics during oral consumption of malt liquor beverages in African Americans. (2008)
• Ethanol's molecular targets. (2008)
• Regulation and function of Zip4, the acrodermatitis enteropathica gene. (2008)
• Chronic binge ethanol-mediated acidemia reduces availability of glutamine and related amino acids in maternal plasma of pregnant sheep. (2008)
• An alcohol binding site on the neural cell adhesion molecule L1. (2008)
• Modeling the impact of alcohol on cortical development in a dish: strategies from mapping neural stem cell fate. (2008)
• Ethanol consumption during early pregnancy alters the disposition of tangentially migrating GABAergic interneurons in the fetal cortex. (2008)
• Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons. (2008)
• Development and tissue origins of the mammalian cranial base. (2008)
• Age at first drink and the first incidence of adult-onset DSM-IV alcohol use disorders. (2008)
• Effects of prenatal ethanol exposure on regulation of basal hypothalamic-pituitary-adrenal activity and hippocampal 5-HT1A receptor mRNA levels in female rats across the estrous cycle. (2008)
• Acid-sensitive channel inhibition prevents fetal alcohol spectrum disorders cerebellar Purkinje cell loss. (2008)
• Differences in acute alcohol-induced behavioral responses among zebrafish populations. (2008)
• Elevated fatty acid ethyl esters in meconium of sheep fetuses exposed in utero to ethanol--a new animal model. (2008)
• Voluntary exercise influences behavioral development in rats exposed to alcohol during the neonatal brain growth spurt. (2008)
• Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol. (2008)
• Neonatal alcohol exposure differentially alters clock gene oscillations within the suprachiasmatic nucleus, cerebellum, and liver of adult rats. (2008)
• Alcohol and inflammation and immune responses: summary of the 2006 Alcohol and Immunology Research Interest Group (AIRIG) meeting. (2008)
• Choline supplementation attenuates learning deficits associated with neonatal alcohol exposure in the rat: effects of varying the timing of choline administration. (2008)
• Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state. (2008)
• Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling. (2008)
• Nrf2-mediated transcriptional induction of antioxidant response in mouse embryos exposed to ethanol in vivo: implications for the prevention of fetal alcohol spectrum disorders. (2008)
• Fetal alcohol spectrum disorders and their persisting sequelae in adult life. (2008)
• Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans. (2008)
• Identification of novel bone-specific molecular targets of binge alcohol and ibandronate by transcriptome analysis. (2008)
• Adolescent development of neuron structure in dentate gyrus granule cells of male Syrian hamsters. (2008)
• Mechanism of alcohol-induced oxidative stress and neuronal injury. (2008)
• Adolescent but not adult rats exhibit ethanol-mediated appetitive second-order conditioning. (2008)
• Effects of alcohol exposure during development on play behavior and c-Fos expression in response to play behavior. (2008)
• A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development. (2008)
• High-resolution magnetic resonance histology of the embryonic and neonatal mouse: a 4D atlas and morphologic database. (2008)
• Prenatal alcohol exposure increases vulnerability to stress and anxiety-like disorders in adulthood. (2008)
• Chronic ethanol consumption leads to disruption of vitamin D3 homeostasis associated with induction of renal 1,25 dihydroxyvitamin D3-24-hydroxylase (CYP24A1). (2008)
• The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum. (2008)
• Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons. (2008)
• Fetal alcohol spectrum disorder-associated depression: evidence for reductions in the levels of brain-derived neurotrophic factor in a mouse model. (2008)
• Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. (2007)
• Clock genes running amok. Clock genes and their role in drug addiction and depression. (2007)
• Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. (2007)
• Mechanisms for persistent microphthalmia following ethanol exposure during retinal neurogenesis in zebrafish embryos. (2007)
• Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes. (2007)
• Purkinje cell dysfunction and alteration of long-term synaptic plasticity in fetal alcohol syndrome. (2007)
• Prenatal ethanol exposure disrupts the histological stages of fetal bone development. (2007)
• Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde. (2007)
• Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system. (2007)
• Agmatine reduces balance deficits in a rat model of third trimester binge-like ethanol exposure. (2007)
• L1 cell adhesion molecule is neuroprotective of alcohol induced cell death. (2007)
• The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. (2007)
• Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. (2007)
• The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. (2007)
• Restoration of neuronal plasticity by a phosphodiesterase type 1 inhibitor in a model of fetal alcohol exposure. (2006)
• Fatty acid ethyl esters in meconium: are they biomarkers of fetal alcohol exposure and effect? (2006)
• Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades. (2006)
• Ethanol inhibits L1 cell adhesion molecule activation of mitogen-activated protein kinases. (2006)
• Characterization of the ethanol-deprivation effect in substrains of C57BL/6 mice. (2006)
• Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. (2006)
• Effects of chronic alcohol and repeated deprivations on dopamine D1 and D2 receptor levels in the extended amygdala of inbred alcohol-preferring rats. (2006)
• Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brain. (2006)
• Effects of ethanol on photoreceptors and visual function in developing zebrafish. (2006)
• Effects of acute and chronic ethanol exposure on the behavior of adult zebrafish (Danio rerio). (2006)
• Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure. (2006)
• Effects of prenatal ethanol exposure and sex on the arginine vasopressin response to hemorrhage in the rat. (2006)
• Ethanol inhibits insulin expression and actions in the developing brain. (2005)
• Fetal alcohol spectrum disorder: Canadian guidelines for diagnosis. (2005)
• Identifying fetal alcohol spectrum disorder in primary care. (2005)
• Identification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging technique. (2004)
• The long-term stability of new hippocampal place fields requires new protein synthesis. (2004)
• Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes. (2004)
• Origins of cortical interneuron subtypes. (2004)
• Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V alcohol dehydrogenase genes but have distinct functional characteristics. (2004)
• Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. (2003)
• Alcohol and the developing brain: neuroanatomical studies. (2003)
• A role for corticotropin releasing factor (CRF) in ethanol consumption, sensitivity, and reward as revealed by CRF-deficient mice. (2003)
• Differential effects of ethanol antagonism and neuroprotection in peptide fragment NAPVSIPQ prevention of ethanol-induced developmental toxicity. (2003)
• Neonatal alcohol exposure induces long-lasting impairment of visual cortical plasticity in ferrets. (2003)
• Transposable elements: targets for early nutritional effects on epigenetic gene regulation. (2003)
• Relationship between availability of NMDA receptor subunits and their expression at the synapse. (2002)
• Alcohol and mitochondria: a dysfunctional relationship. (2002)
• Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure. (2002)
• Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death. (2002)
• Eyeblink classical conditioning and interpositus nucleus activity are disrupted in adult rats exposed to ethanol as neonates. (2002)
• Drug-induced apoptotic neurodegeneration in the developing brain. (2002)
• Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia. (2002)
• Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain. (2001)
• Mechanisms of alcohol-induced damage to the developing nervous system. (2001)
• Influence of the endogenous opioid system on high alcohol consumption and genetic predisposition to alcoholism. (2001)
• Neurotoxic hippocampal lesions have no effect on odor span and little effect on odor recognition memory but produce significant impairments on spatial span, recognition, and alternation. (2000)
• Modeling alcohol's effects on organs in animal models. (2000)
• Exposure of rats to a high but not low dose of ethanol during early postnatal life increases the rate of loss of optic nerve axons and decreases the rate of myelination. (2000)
• Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. (2000)
• Antagonists of alcohol inhibition of cell adhesion. (2000)
• Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter/enhancer. (2000)
• Role of founder cell deficit and delayed neuronogenesis in microencephaly of the trisomy 16 mouse. (2000)
• Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme. (2000)
• Temporally graded retrograde amnesia of contextual fear after hippocampal damage in rats: within-subjects examination. (1999)
• Ethyl linoleate in meconium: a biomarker for prenatal ethanol exposure. (1999)
• Effect of enriched environment rearing on impairments in cortical excitability and plasticity after prenatal alcohol exposure. (1999)
• Biochemical and morphometric analyses show that myelination in the insulin-like growth factor 1 null brain is proportionate to its neuronal composition. (1998)
• The hormonal effects of alcohol use on the mother and fetus. (1998)
• The hematological complications of alcoholism. (1997)
• Alcohol-induced cell death in the embryo. (1997)
• Gestational exposure to ethanol suppresses msx2 expression in developing mouse embryos. (1997)
• The endocrine system: alcohol alters critical hormonal balance. (1997)
• Effects of chronic treatment with delta9-tetrahydrocannabinol on cannabinoid-stimulated [35S]GTPgammaS autoradiography in rat brain. (1996)
• Alcohol inhibits cell-cell adhesion mediated by human L1. (1996)
• Loss of myelinated axons is specific to the central nervous system in a mouse model of the fetal alcohol syndrome. (1995)
• MRI and Prenatal Alcohol Exposure: Images Provide Insight Into FAS. (1994)
• First BYD 100% Electric Vehicle Rolls off the Line in Brazil

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