Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective.

paper Primary Public

Authors: Su, Jinni; Kuo, Sally I-Chun; Aliev, Fazil; Guy, Mignonne C; Derlan, Chelsea L; Edenberg, Howard J; Nurnberger, John I; Kramer, John R; Bucholz, Kathleen K; Salvatore, Jessica E; Dick, Danielle M
Year: 2018
Journal: Alcoholism, clinical and experimental research
PMID: 29969154
DOI: 10.1111/acer.13827
PMCID: PMC6120770

#	Section	Preview
40	Discussion	Consistent with expectations, our bivariate correlations analyses indicated that both fathers’ and…
41	Discussion	environmental stress and negative affect (Chassin et al., 1993) and more family conflict (Loukas et…
42	Discussion	Interestingly, results from our multivariate SEM model indicated that fathers’ but not mothers’…
43	Discussion	of the unique effects of fathers’ and mothers’ parenting. It is interesting that results from…
44	Discussion	Pathways of risk did not vary across European American and African American adolescents, suggesting…
45	Discussion	et al., 2002; Ohannessian et al., 2005), but contradict others that suggested stronger influence of…
46	Discussion — Limitations	Our findings need to be interpreted in light of several limitations. First, the assessment of…
47	Discussion — Limitations	outcomes in offspring (Conway et al., 2004; Schepis et al., 2008). Prior research also suggests that…
48	Discussion — Limitations	Second, we only focused on positive parenting because our measures of negative parenting were weak…
49	Discussion — Limitations	The large amount of missing data for fathers is another limitation. We note, however, that there was…
50	Discussion — Limitations	Another limitation is that we only included EA and AA adolescents in this study. Future research…
51	Conclusion	Despite several limitations, this study has many strengths, including the clinical assessment of ADS…

Name	Type
AA	cohort
Adolescent age local	phenotype
adolescent alcohol use	phenotype
adolescent conduct problems	phenotype
adolescent drinking	phenotype
Adolescent ethnicity local	phenotype
Adolescent gender local	phenotype
Adolescent outcomes local	phenotype
adolescents	cohort
Adolescents' conduct problems local	phenotype
adolescents' risky drinking local	phenotype
Adolescents' risky drinking local	phenotype
Adolescents’ risky drinking local	phenotype
adolescent substance use	phenotype
African American	cohort
age	phenotype
aggression	phenotype
alcohol	phenotype
alcohol abuse	phenotype
alcohol dependence	phenotype
Alcohol Dependence Symptoms	phenotype
alcoholism	phenotype
Alcohol Problems	phenotype
Alcohol problems later in life local	phenotype
Alcohol Use	phenotype
Alcohol Use Disorder	phenotype
antisocial personality disorder	phenotype
anxiety symptoms	phenotype
authoritarian parenting style local	phenotype
Authoritarian parenting style local	phenotype
Biological parents	cohort
CDSX local	phenotype
COGA adult interviews local	cohort
COGA extended families local	cohort
COGA sample	cohort
Collaborative Study on the Genetics of Alcoholism (COGA)	cohort
communication	phenotype
conduct disorder	phenotype
conduct_problems local	phenotype
Daughters local	cohort
Daughters local	phenotype
delinquency	phenotype
depressive symptoms	phenotype
discipline	phenotype
DSM-IV	phenotype
DSM-IV alcohol dependence	phenotype
EA	cohort
early alcohol use	phenotype
environmental stress	phenotype
European ancestry	cohort
externalizing disorders	phenotype
Families with ADS data local	cohort
families with both biological parents local	cohort
family conflict	phenotype
Family socioeconomic status	phenotype
family structure	phenotype
Father-adolescent closeness local	phenotype
Father-adolescent communication local	phenotype
Father ADS local	phenotype
father-child closeness local	phenotype
father-child communication local	phenotype
Father parenting behaviors local	phenotype
Father positive parenting behaviors local	phenotype
fathers	cohort
father's ADS local	phenotype
fathers' ADS local	phenotype
Fathers' ADS local	phenotype
Fathers' alcohol dependence local	phenotype
Fathers' Alcohol Dependence Symptoms local	phenotype
father's parenting local	phenotype
fathers' parenting local	phenotype
Fathers' parenting local	phenotype
Fathers' parenting behaviors local	phenotype
Fathers' positive parenting local	phenotype
fathers' positive parenting behaviors local	phenotype
heavy drinking	phenotype
internalizing disorders	phenotype
involvement	phenotype
Lower involvement local	phenotype
major depressive disorder	phenotype
maternal_ADS local	phenotype
maternal antisocial behavior	phenotype
Maternal antisocial behaviors local	phenotype
maternal involvement local	phenotype
Maternal involvement local	phenotype
Maternal monitoring local	phenotype
Maternal support local	phenotype
Mother-adolescent closeness local	phenotype
Mother-adolescent communication local	phenotype
Mother ADS local	phenotype
mother-child closeness local	phenotype
Mother-child closeness local	phenotype
mother-child communication local	phenotype
Mother-child communication local	phenotype
Mother parenting behaviors local	phenotype
Mother positive parenting behaviors local	phenotype
mothers	cohort
mother's ADS local	phenotype
mothers' ADS local	phenotype
Mothers' ADS local	phenotype
Mothers' alcohol dependence local	phenotype
Mothers' Alcohol Dependence Symptoms local	phenotype
mother's parenting local	phenotype
mothers' parenting local	phenotype
Mothers' parenting local	phenotype
Mothers' parenting behaviors local	phenotype
Mothers' positive parenting local	phenotype
mothers' positive parenting behaviors local	phenotype
negative affect	phenotype
negative parenting	phenotype
Negative parenting practices local	phenotype
Non-biological father local	cohort
non-biological father figure local	phenotype
Non-biological mother local	cohort
non-biological mother figure local	phenotype
offspring alcohol problems	phenotype
Offspring maladaptive outcomes local	phenotype
offspring outcomes	cohort
Parental Alcohol Dependence Scale local	phenotype
Parental alcohol dependence symptoms local	phenotype
Parental Alcohol Dependence Syndrome local	phenotype
parental alcoholism	phenotype
Parental antisocial personality disorder local	phenotype
parental closeness	phenotype
parental control	phenotype
parental divorce/separation	phenotype
parental education	phenotype
parental involvement	phenotype
parental monitoring	phenotype
Parental support	phenotype
parental warmth	phenotype
parent-child closeness local	phenotype
Parent-child closeness local	phenotype
parent-child closeness scale local	phenotype
parent-child communication	phenotype
parent-child communication scale local	phenotype
parenting	phenotype
Paternal antisocial behavior local	phenotype
Paternal antisocial behaviors local	phenotype
paternal involvement local	phenotype
Paternal involvement local	phenotype
Paternal monitoring local	phenotype
Poor parent-child communication local	phenotype
positive parenting	phenotype
prenatal alcohol exposure	phenotype
problematic alcohol use	phenotype
Prospective Study	cohort
Psychosocial Outcomes in Offspring local	phenotype
race/ethnicity	phenotype
risky drinking	phenotype
risky_drinking local	phenotype
Same-sex parent-adolescent dyad local	cohort
self-reported parenting behaviors local	phenotype
sex	phenotype
sons	cohort
Sons local	phenotype
stress	phenotype
subsample (n=706) local	cohort
subsample (n=929) local	cohort
substance use	phenotype
Time involvement local	phenotype
whole sample local	cohort

Citation	PMID	DOI	Status
Acion, L et al., 2017, Associations between internalizing characteristics and substance use in adults from families at high risk for alcoholism	—	—	—
Amato, PR et al., J Marriage Fam, 2002, Parenting practices, child adjustment, and family diversity	—	—	—
Armstrong, TD et al., J Consult Clin Psychol, 2002, Community studies on adolescent substance use, abuse, or dependence and psychiatric comorbidity	12472299	10.1037//0022-006x.70.6.1224	Cited
Barnes, GM et al., J Marriage Fam, 2000, The Effects of parenting on the development of adolescent alcohol misuse: A six-wave latent growth model	—	—	—
Begleiter, H et al., Alcohol Health Res World, 1995, The Collaborative Study on the Genetics of Alcoholism	31798102	—	Primary
Borawski, EA et al., J Adolesc Health, 2003, Parental monitoring, negotiated unsupervised time, and parental trust: The role of perceived parenting practices in adolescent health risk behaviors	12890596	10.1016/s1054-139x(03)00100-9	Cited
Brown, SL et al., J Res Adolesc, 2010, Family structure, family processes, and adolescent smoking and drinking	20543893	10.1111/j.1532-7795.2010.00636.x	Cited
Bucholz, KK et al., Alcohol Clin Exp Res, 2017, Comparison of parent, peer, psychiatric, and cannabis use influences across stages of offspring alcohol involvement: evidence from the COGA prospective study	28073157	10.1111/acer.13293	Primary
Bucholz, KK et al., J Stud Alcohol, 1994, A new, semi-structured psychiatric interview for use in genetic linkage studies: A report on the reliability of the SSAGA	8189735	10.15288/jsa.1994.55.149	Primary
Byrne, BM et al., J Cross-Cult Psychol, 2003, The issue of measurement invariance revisited	—	—	—
Chassin, L et al., J Abnorm Psychol, 1993, Relation of parental alcoholism to early adolescent substance use: A test of three mediating mechanisms	8436697	10.1037//0021-843x.102.1.3	Cited
Chassin, L et al., J Abnorm Psychol, 1996, The relation of parent alcoholism to adolescent substance use: A longitudinal follow-up study	8666713	10.1037//0021-843x.105.1.70	Cited
Chassin, L et al., J Abnorm Psychol, 2004, Trajectories of alcohol and drug use and dependence from adolescence to adulthood: The effects of familial alcoholism and personality	15535782	10.1037/0021-843X.113.4.483	Cited
Cheung, GW et al., Struct Equ Model, 2002, Evaluating goodness-of-fit indexes for testing measurement invariance	—	—	—
Clark, TT et al., Health Psychol, 2015, Racial differences in parenting style typologies and heavy episodic drinking trajectories	25222086	10.1037/hea0000150	Cited
Conway, KP et al., Addict Behav, 2003, Alcohol expectancies, alcohol consumption, and problem drinking: the moderating role of family history	12788259	10.1016/s0306-4603(02)00265-4	Cited
Cox, MJ et al., Curr Dir Psychol Sci, 2003, Understanding families as systems	—	—	—
Dallaire, DH et al., J Clin Child Adolesc Psychol, 2006, Relation of positive and negative parenting to children’s depressive symptoms	16597227	10.1207/s15374424jccp3502_15	Cited
Data spotlight: Over 7 million children live with a parent with alcohol problems, 2012	—	—	—
Dawson, DA et al., Drug Alcohol Depend, 2010, Gender differences in the relationship of internalizing and externalizing psychopathology to alcohol dependence: likelihood, expression and course	20558014	10.1016/j.drugalcdep.2010.04.019	Cited
Deater-Deckard, K et al., Psychol Inquiry, 1997, Externalizing behavior problems and discipline revisited: Nonlinear effects and variations by culture, context, and gender	—	—	—
Deutsch, AR et al., J Youth Adolescence, 2012, Parent and peer pathways to adolescent delinquency: Variations by ethnicity and neighborhood context	22460729	10.1007/s10964-012-9754-y	Cited
Diagnostic and statistical manual of mental disorders, 1994	—	—	—
Edwards, AC et al., Addict Behav, 2017, Time-specific and cumulative effects of exposure to parental externalizing behavior on risk for young adult alcohol use disorder	28319814	10.1016/j.addbeh.2017.03.002	Cited
Elkins, IJ et al., Am J Psychiatry, 2004, The effect of parental alcohol and drug disorders on adolescent personality	15056513	10.1176/appi.ajp.161.4.670	Cited
Enders, CK, Applied missing data analysis, 2010	—	—	—
Finan, LJ et al., J Adolesc, 2015, Parental problem drinking and adolescent externalizing behaviors: The mediating role of family functioning	26073673	10.1016/j.adolescence.2015.05.001	Cited
Goodman, E et al., Arch Pediatr Adolesc Med, 2002, Socioeconomic status, depressive symptoms, and adolescent substance use	11980549	10.1001/archpedi.156.5.448	Cited
Graham, JW et al., Research methods in psychology, 2003, Methods for handling missing data	—	—	—
Hicks, BM et al., J Abnorm Psychol, 2007, Gender differences and developmental change in externalizing disorders from late adolescence to early adulthood: A longitudinal twin study	17696699	10.1037/0021-843X.116.3.433	Cited
Hussong, AM et al., J Abnorm Child Psychol, 2010, Parent alcoholism impacts the severity and timing of children’s externalizing symptoms	20084453	10.1007/s10802-009-9374-5	Cited
Johnston, LD et al., Monitoring the Future national survey results on drug use: 1975–2014: Overview, key findings on adolescent drug use, 2015	—	—	—
Kachadourian, LK et al., Addict Behav, 2009, Paternal alcoholism, negative parenting, and the mediating role of marital satisfaction	19541430	10.1016/j.addbeh.2009.05.003	Cited
Kelly, AB et al., Addiction, 2011, Gender differences in the impact of families on alcohol use: A lagged longitudinal study of early adolescents	21438936	10.1111/j.1360-0443.2011.03435.x	Cited
Kenny, DA, Measuring model fit, 2014	—	—	—
Klevens, J et al., J Child Adolesc Behav, 2014, The importance of parental warmth, support, and control in preventing adolescent misbehavior	—	—	—
Kuperman, S et al., J Am Acad Child Adolesc Psychiatry, 1999, Relationship of child psychopathology to parental alcoholism and antisocial personality disorder	10361786	10.1097/00004583-199906000-00015	Primary
Leidy, MS et al., Fathering, 2011, Fathering and adolescent adjustment: Variations by family structure and ethnic background	24235877	10.3149/fth.0901.44	Cited
Leonard, KE et al., Ann Rev Clin Psychol, 2007, Marital and family processes in the context of alcohol use and alcohol disorders	17716057	10.1146/annurev.clinpsy.3.022806.091424	Cited
Lieb, R et al., Psychol Med, 2002, Parental alcohol use disorders and alcohol use and disorders in offspring: A community study	11883731	10.1017/s0033291701004883	Cited
Loukas, A et al., J Abnorm Child Psychol, 2001, Parental alcoholism and co-occurring antisocial behavior: Prospective relationships to externalizing behavior problems in their young sons	11321632	10.1023/a:1005281011838	Cited
Luk, JW et al., Addict Behav, 2010, Parent–child communication and substance use among adolescents: Do father and mother communication play a different role for sons and daughters?	20060651	10.1016/j.addbeh.2009.12.009	Cited
MacKinnon, DP, Introduction to statistical mediation analysis, 2008	—	—	—
Marceau, K et al., J Child Psychol Psychiatry, 2015, Parental knowledge is an environmental influence on adolescent externalizing	24975929	10.1111/jcpp.12288	Cited
Marshall, EJ, Alcohol Alcohol, 2014, Adolescent alcohol use: Risks and consequences	24402246	10.1093/alcalc/agt180	Cited
Mason, CA et al., J Prim Prev, 2004, Ethnic differences in the affective meaning of parental control behaviors	—	—	—
McLaughlin, KA et al., J Abnorm Child Psychol, 2007, Racial/ethnic differences in internalizing and externalizing symptoms in adolescents	17508278	10.1007/s10802-007-9128-1	Cited
Merikangas, KR et al., Dialogues Clin Neurosci, 2009, Epidemiology of mental disorders in children and adolescents	19432384	10.31887/DCNS.2009.11.1/krmerikangas	Cited
Morgan, PT et al., Alcohol Clin Exp Res, 2010, Gender-related influences of parental alcoholism on the prevalence of psychiatric illnesses: Analysis of the National Epidemiologic Survey on Alcohol and Related Conditions	20645936	10.1111/j.1530-0277.2010.01263.x	Cited
Muthén, LK et al., Mplus User’s Guide	—	—	—
Oetting, E et al., Subst Use Misuse, 1998, Primary socialization theory: The etiology of drug use and deviance. I	9548633	10.3109/10826089809056252	Cited
Ohannessian, CM et al., J Abnorm Child Psychol, 2004, The relationship between parental alcoholism and adolescent psychopathology: A systematic examination of parental comorbid psychopathology	15500031	10.1023/b:jacp.0000037781.49155.a6	Primary
Ohannessian, CM et al., J Emot Behav Disord, 2005, The relationship between parental psychopathology and adolescent psychopathology: An examination of gender patterns	—	—	—
Ohannessian, CM, J Res Adolesc, 2012, Parental problem drinking and adolescent psychosocial adjustment: The mediating role of adolescent-parent communication	—	—	—
Park, S et al., J Child Fam Stud, 2015, A systematic review of research on children of alcoholics: Their inherent resilience and vulnerability	—	—	—
Piotrowska, PJ et al., Clin Psychol Rev, 2015, Socioeconomic status and antisocial behavior among children and adolescents: A systematic review and meta-analysis	25483561	10.1016/j.cpr.2014.11.003	Cited
Reich, W et al., Br J Addict, 1988, A comparison of the home and social environments of children of alcoholic and non-alcoholic parents	3207941	10.1111/j.1360-0443.1988.tb00518.x	Cited
Riley, EP et al., Neuropsychol Rev, 2011, Fetal alcohol spectrum disorders: an overview	21499711	10.1007/s11065-011-9166-x	Cited
Rubin, DB, Multiple imputation for nonresponse in surveys, 1987	—	—	—
Ryan, SM et al., Aust N Z J Psychiatry, 2010, Parenting factors associated with reduced adolescent alcohol use: A systematic review of longitudinal studies	20815663	10.1080/00048674.2010.501759	Cited
Schepis, TS et al., J Addict Med, 2008, Impulsive sensation seeking, parental history of alcohol problems, and current alcohol and tobacco use in adolescents	19956365	10.1097/adm.0b013e31818d8916	Cited
Schulte, MT et al., Clin Psychol Rev, 2009, Gender differences in factors influencing alcohol use and drinking progression among adolescents	19592147	10.1016/j.cpr.2009.06.003	Cited
Shelton, KH et al., J Res Adolesc, 2010, The moderating effects of pubertal timing on the longitudinal associations between parent-child relationship quality and adolescent substance use	21170159	10.1111/j.1532-7795.2010.00643.x	Cited
Shorey, RC et al., J Prim Prev, 2013, The association between problematic parental substance use and adolescent substance use in an ethnically diverse sample of 9th and 10th graders	24006209	10.1007/s10935-013-0326-z	Cited
Skinner, ML et al., Cultur Divers Ethnic Minor Psychol, 2011, Observed parenting behavior with teens: Measurement invariance and predictive validity across race	21787057	10.1037/a0024730	Cited
Steenkamp, JM et al., J Consumer Res, 1998, Assessing measurement invariance in cross-national consumer research	—	—	—
Tebes, JK et al., J Child Fam Stud, 2011, Parental knowledge and substance use among African American adolescents: Influence of gender and grade level	24683304	10.1007/s10826-010-9406-3	Cited
Waldron, M et al., Drug Alcohol Depend, 2014, Risks for early substance involvement associated with parental alcoholism and parental separation in an adolescent female cohort	24647368	10.1016/j.drugalcdep.2014.02.020	Cited
Waldron, M et al., Twin Res Hum Genet, 2009, Parental alcoholism and offspring behavior problems: Findings in Australian children of twins	19803771	10.1375/twin.12.5.433	Cited
White, JM et al., Family theories, 2002	—	—	—

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