Genetic architectures of psychiatric disorders: the emerging picture and its implications.

paper Cited Public

Authors: Sullivan, Patrick F; Daly, Mark J; O'Donovan, Michael
Year: 2012
Journal: Nature reviews. Genetics
PMID: 22777127
DOI: 10.1038/nrg3240
PMCID: PMC4110909

Figure 1

Results pertaining to genetic architecture(a) Plot of heritability by log10 lifetime prevalence for nine psychiatric disorders considered in this review plus three complex diseases for which genetic dissection has been particularly successful (Tables 1 and S1). Each disorder is plotted by as heritability by lifetime prevalence. Color indicates qualitative success in identifying etiological genetic variation (green=notably successful, khaki=some successes, red=minimal or no clear success to date). The bubble sizes are proportional to the numbers of cases studied in GWAS (the smaller circle indicating discovery Ncase and the larger circle the total Ncase for discovery plus replication samples). Abbreviations: ADHD=attention-deficit hyperactivity disorder, ALC=alcohol dependence, AD=Alzheimer’s disease, AN=anorexia nervosa, ASD=autism, BIP=bipolar disorder, BRCA=breast cancer, CD=Crohn’s disease, MDD=major depressive disorder, NIC=nicotine usage (maximum cigarettes per day), SCZ=schizophrenia, and T2DM=type 2 diabetes mellitus.(b) Allelic spectrum of SCZ. The inset is a conceptual schematic from a 2008 Nature Genetics review. 10 The lower part of the figure depicts empirical results for SCZ. The x-axis is log10(AF) in controls. The y-axis is the point estimate for genotypic relative risk (GRR, log10). For clarity, confidence intervals are not shown. There are no known Mendelian variants for SCZ (AF ≪ 0.0001, GRR ≫ 50). There are no known common variants (AF > 0.05) with GRR > 1.5, and these can be excluded with > 99% statistical power. Nine SVs associated with SCZ are shown as light blue diamonds (Table 2, 1q21.1- is the deletion and 1q21.1+ is the duplication). If AF in controls was 0, AF was set to 0.0001. These SVs do not have a corresponding region in the inset. Seventeen common variants have been associated with SCZ (red circles, Table 3). SNPs contributing to the PGC SCZ risk profile score 58 (21,171 autosomal SNPs with PT < 0.1, Box 3, panel b) are shown in light blue dots with a lowess smoother in dark blue.

#	Section	Preview
20	Autism Spectrum Disorders (ASD) — Rare variation	Analysis of SV has been a major focus in ASD research (Table 2, Figure S1). Implicated loci to date…
21	Autism Spectrum Disorders (ASD) — Rare variation	ASD is the first psychiatric disorder for which exome sequencing using substantial numbers of…
22	Autism Spectrum Disorders (ASD) — Rare variation	However, a central finding from these papers was that only a minority of cases had a de novo…
23	Autism Spectrum Disorders (ASD) — Common variation	Evaluation of rare SV and exonic variation in ASD is particularly advanced. In contrast, evaluation…
24	Alcohol and Nicotine Dependence (ALC & NIC)	ALC and NIC are complex conditions to study, given the requirement for ingestion of a psychoactive…
25	Alcohol and Nicotine Dependence (ALC & NIC)	For ALC, the published GWAS are small and no large-scale meta-analysis has been conducted. 93–97…
26	Alcohol and Nicotine Dependence (ALC & NIC)	For NIC, a field-wide meta-analysis is also needed. For smoking behavior, large meta-analyses have…
27	Major Depressive Disorder (MDD)	The PGC GWAS mega-analysis of 9,240 MDD cases and 9,519 controls (replication in 6,783 MDD cases)…
28	Major Depressive Disorder (MDD)	A provocative finding from 2003 was that risk for MDD might be influenced by a gene-environment…
29	Other disorders (ADHD and AN)	The published GWAS for ADHD 116 and AN 117 are small, but larger samples are in progress (e.g., by…
30	What is the Emerging Picture	Knowledge of psychiatric genetics is vastly greater than it was five years ago. Specifically, there…
31	What is the Emerging Picture — Genetic architecture	These results also provide insights into genetic architecture that are critical for planning more…
32	What is the Emerging Picture — Genetic architecture	For several disorders, there are now data to replace the interminable debate about the fundamental…
33	What is the Emerging Picture — Genetic architecture	For disorders with sufficient data (AD, BIP, and SCZ), the results are consistent with an allelic…
34	What is the Emerging Picture — Genetic architecture	Hypothesized genetic architectures consisting entirely of rare variants are inconsistent with the…
35	What is the Emerging Picture — Genetic architecture	Psychiatric disorders are polygenic. The evidence is strong that many genes are involved in the…
36	What is the Emerging Picture — Genetic architecture	Polygenicity may be a general feature of complex biomedical diseases. 128,129 Common variant SNP…
37	What is the Emerging Picture — Genetic architecture	As discussed further below, currently we do not now possess a comprehensive enumeration of loci…
38	Implications and Future Directions — Why these successes matter	As other commentators have written, 70,128,134,135 and as we argued in early 2009, 123 the proximal…
39	Implications and Future Directions — Why these successes matter	What about clinical utility? So-called personalized medicine has been touted as the critical…

Citation	PMID	DOI	Status
Addington, J et al., Annual review of clinical psychology, 2012, Prediction and prevention of psychosis in youth at clinical high risk	22224837	10.1146/annurev-clinpsy-032511-143146	Cited
Alkan, C et al., Nature Reviews Genetics, 2011, Genome structural variation discovery and genotyping	21358748	10.1038/nrg2958	Cited
Altshuler, D et al., Nat Genet, 2007, Guilt beyond a reasonable doubt	17597768	10.1038/ng0707-813	Cited
American Journal of Psychiatry, 2009, Genome-wide association studies: history rationale and prospects for psychiatric disorders	19339359	10.1176/appi.ajp.2008.08091354	Cited
Anderson, CA et al., PLoS Biol, 2011, Synthetic associations are unlikely to account for many common disease genome-wide association signals	21267062	10.1371/journal.pbio.1000580	Cited
Anney, R, Human molecular genetics, 2010, A genome-wide scan for common alleles affecting risk for autism	20663923	10.1093/hmg/ddq307	Primary
Aoun, S et al., Australian and New Zealand journal of public health, 2004, To what extent is health and medical research funding associated with the burden of disease in Australia?	15108752	10.1111/j.1467-842x.2004.tb00637.x	Cited
Arcelus, J et al., Archives of general psychiatry, 2011, Mortality rates in patients with anorexia nervosa and other eating disorders. A meta-analysis of 36 studies	21727255	10.1001/archgenpsychiatry.2011.74	Cited
Attia, J, Jama, 2009, How to use an article about genetic association: A: Background concepts	19126812	10.1001/jama.2008.901	Cited
Baik, I et al., The American journal of clinical nutrition, 2011, Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men	21270382	10.3945/ajcn.110.001776	Cited
Barabasi, AL et al., Nature reviews. Genetics, 2011, Network medicine: a network-based approach to human disease	21164525	10.1038/nrg2918	Cited
Bassett, AS et al., Am J Med Genet, 2000, Chromosomal abnormalities and schizophrenia	10813803	10.1002/(sici)1096-8628(200021)97:1<45::aid-ajmg6>3.0.co;2-9	Cited
Bemis, LT, Cancer research, 2008, MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines	18316599	10.1158/0008-5472.CAN-07-2912	Cited
Bertram, L et al., Nature Reviews Neuroscience, 2008, Thirty years of Alzheimer’s disease genetics: the implications of systematic meta-analyses	18802446	10.1038/nrn2494	Cited
Betancur, C, Brain Res, 2011, Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still counting	21129364	10.1016/j.brainres.2010.11.078	Cited
Biederman, J et al., MedGenMed : Medscape general medicine, 2006, The effects of attention-deficit/hyperactivity disorder on employment and household income	17406154	—	Cited
Bierut, LJ, Molecular psychiatry, 2011, ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry	21968928	10.1038/mp.2011.124	Primary
Bierut, LJ, Proceedings of the National Academy of Sciences of the United States of America, 2010, A genome-wide association study of alcohol dependence	20202923	10.1073/pnas.0911109107	Primary
Breen, G, Nature Genetics, 2011, Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depression	21217634	10.1038/ng0111-3	Cited
Brouwers, N, Molecular psychiatry, 2012, Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites	21403675	10.1038/mp.2011.24	Cited
Brunetti-Pierri, N, Nature genetics, 2008, Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities	19029900	10.1038/ng.279	Cited
Cantor, RM et al., American journal of human genetics, 2010, Prioritizing GWAS results: A review of statistical methods and recommendations for their application	20074509	10.1016/j.ajhg.2009.11.017	Cited
Caspi, A, Science, 2003, Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene	12869766	10.1126/science.1083968	Cited
Chanock, SJ, Nature, 2007, Replicating genotype-phenotype associations	17554299	10.1038/447655a	Cited
Chiurazzi, P et al., European journal of human genetics : EJHG, 2008, XLMR genes: update 2007	18197188	10.1038/sj.ejhg.5201994	Cited
Cichon, S, Am J Hum Genet, 2011, Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder	21353194	10.1016/j.ajhg.2011.01.017	Cited
Cirulli, ET et al., Nature reviews. Genetics, 2010, Uncovering the roles of rare variants in common disease through whole-genome sequencing	20479773	10.1038/nrg2779	Cited
Collins, AL, Psychological Medicine, 2012, Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results	21854684	10.1017/S0033291711001607	Cited
Collins, PY, Nature, 2011, Grand challenges in global mental health	21734685	10.1038/475027a	Cited
Cooper, GM, Nature genetics, 2011, A copy number variation morbidity map of developmental delay	21841781	10.1038/ng.909	Cited
Corvin, A et al., Psychologal Medicine, 2010, Genome-wide association studies: a primer	19895722	10.1017/S0033291709991723	Cited
Croning, MD et al., Nucleic acids research, 2009, G2Cdb: the Genes to Cognition database	18984621	10.1093/nar/gkn700	Cited
Davies, G, Molecular psychiatry, 2011, Genome-wide association studies establish that human intelligence is highly heritable and polygenic	21826061	10.1038/mp.2011.85	Cited
de Bakker, PI et al., Cold Spring Harbor protocols, 2010, Meta-analysis of genome-wide association studies	20516189	10.1101/pdb.top81	Cited
de Bakker, PI, Hum Mol Genet, 2008, Practical aspects of imputation-driven meta-analysis of genome-wide association studies	18852200	10.1093/hmg/ddn288	Cited
Diagnostic and Statistical Manual of Mental Disorders, 1994	—	—	—
Dickson, SP et al., PLoS Biol, 2010, Rare variants create synthetic genome-wide associations	20126254	10.1371/journal.pbio.1000294	Cited
Durbin, RM, Nature, 2010, A map of human genome variation from population-scale sequencing	20981092	10.1038/nature09534	Cited
Easton, DF, Nature, 2007, Genome-wide association study identifies novel breast cancer susceptibility loci	17529967	10.1038/nature05887	Cited
Eaton, WW, Epidemiologic reviews, 2008, The burden of mental disorders	18806255	10.1093/epirev/mxn011	Cited
Edenberg, HJ, Alcoholism, clinical and experimental research, 2010, Genome-wide association study of alcohol dependence implicates a region on chromosome 11	20201924	10.1111/j.1530-0277.2010.01156.x	Primary
Eichler, EE, Nature reviews. Genetics, 2010, Missing heritability and strategies for finding the underlying causes of complex disease	20479774	10.1038/nrg2809	Cited
Fergusson, DM et al., The British journal of psychiatry : the journal of mental science, 2011, Life stress, 5-HTTLPR and mental disorder: findings from a 30-year longitudinal study	21282783	10.1192/bjp.bp.110.085993	Cited
Ferreira, M, Nature Genetics, 2008, Collaborative genome-wide association analysis of 10,596 individuals supports a role for Ankyrin-G (ANK3) and the alpha-1C subunit of the L-type voltage-gated calcium channel (CACNA1C) in bipolar disorder	18711365	10.1038/ng.209	Cited
Folstein, SE et al., Nat Rev Genet, 2001, Genetics of autism: complex aetiology for a heterogeneous disorder	11733747	10.1038/35103559	Cited
Fowler, CD et al., Nature, 2011, Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake	21278726	10.1038/nature09797	Cited
Frank, J, Addiction biology, 2012, Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster	22004471	10.1111/j.1369-1600.2011.00395.x	Cited
Franke, A, Nat Genet, 2010, Genome-wide meta-analysis increases to 71 the number of confirmed Crohn’s disease susceptibility loci	21102463	10.1038/ng.717	Cited
Gillum, LA, PloS one, 2011, NIH disease funding levels and burden of disease	21383981	10.1371/journal.pone.0016837	Cited
Girard, SL, Nature genetics, 2011, Increased exonic de novo mutation rate in individuals with schizophrenia	21743468	10.1038/ng.886	Cited
Green, EK, Molecular psychiatry, 2010, The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia	19621016	10.1038/mp.2009.49	Cited
Gross, CP et al., The New England journal of medicine, 1999, The relation between funding by the National Institutes of Health and the burden of disease	10369852	10.1056/NEJM199906173402406	Cited
Grozeva, D, Archives of general psychiatry, 2010, Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia	20368508	10.1001/archgenpsychiatry.2010.25	Cited
Guerreiro, RJ et al., Biochemical Society transactions, 2011, Alzheimer’s disease genetics: lessons to improve disease modelling	21787322	10.1042/BST0390910	Cited
Guerreiro, RJ, Neurobiology of aging, 2012, Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer’s disease	22153900	10.1016/j.neurobiolaging.2011.10.009	Cited
Harold, D, Nature genetics, 2009, Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer’s disease	19734902	10.1038/ng.440	Cited
Heath, AC, Biological psychiatry, 2011, A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications	21529783	10.1016/j.biopsych.2011.02.028	Cited
Hindorff, LA, Proc Natl Acad Sci U S A, 2009, Potential etiologic and functional implications of genome-wide association loci for human diseases and traits	19474294	10.1073/pnas.0903103106	Cited
Hirschhorn, JN, N Engl J Med, 2009, Genomewide association studies--illuminating biologic pathways	19369661	10.1056/NEJMp0808934	Cited
Hollingworth, P, Nature genetics, 2011, Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer’s disease	21460840	10.1038/ng.803	Cited
Holmans, P, Am J Hum Genet, 2009, Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder	19539887	10.1016/j.ajhg.2009.05.011	Cited
Houlston, RS, Nature genetics, 2010, Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33	20972440	10.1038/ng.670	Cited
Inlow, JK et al., Genetics, 2004, Molecular and comparative genetics of mental retardation	15020472	10.1093/genetics/166.2.835	Cited
Itsara, A, American journal of human genetics, 2009, Population analysis of large copy number variants and hotspots of human genetic disease	19166990	10.1016/j.ajhg.2008.12.014	Cited
Jacquemont, S, Nature, 2011, Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus	21881559	10.1038/nature10406	Cited
Jones, L, PloS one, 2010, Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer’s disease	21085570	10.1371/journal.pone.0013950	Cited
Kanehisa, M et al., Nucleic acids research, 2012, KEGG for integration and interpretation of large-scale molecular data sets	22080510	10.1093/nar/gkr988	Cited
Karg, K et al., Archives of general psychiatry, 2011, The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation	21199959	10.1001/archgenpsychiatry.2010.189	Cited
Kendler, KS, Alcoholism, clinical and experimental research, 2011, Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample	21314694	10.1111/j.1530-0277.2010.01427.x	Cited
Khatri, P et al., PLoS computational biology, 2012, Ten years of pathway analysis: current approaches and outstanding challenges	22383865	10.1371/journal.pcbi.1002375	Cited
Kiezun, A, Exome sequencing and the genetic basis of complex traits	22641211	10.1038/ng.2303	Cited
Kim, Y et al., Schizophrenia Bulletin, 2011, Schizophrenia genetics: where next?	21505112	10.1093/schbul/sbr031	Cited
Kirov, G, Molecular psychiatry, 2011, De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia	22083728	10.1038/mp.2011.154	Cited
Kumar, RA, Human molecular genetics, 2008, Recurrent 16p11.2 microdeletions in autism	18156158	10.1093/hmg/ddm376	Cited
Kwon, E et al., Molecular psychiatry, 2011, Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets	22182936	10.1038/mp.2011.170	Cited
Lamarre-Cliche, M et al., Clinical and investigative medicine. Medecine clinique et experimentale, 2001, Association between the burden of disease and research funding by the Medical Research Council of Canada and the National Institutes of Health. A cross-sectional study	11368150	—	Cited
Lambert, JC, Nature genetics, 2009, Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer’s disease	19734903	10.1038/ng.439	Cited
Lander, ES, Nature, 2011, Initial impact of the sequencing of the human genome	21307931	10.1038/nature09792	Cited
Lango Allen, H, Nature, 2010, Hundreds of variants clustered in genomic loci and biological pathways affect human height	20881960	10.1038/nature09410	Cited
Lee, P et al., Bioinformatics, InRich: Interval-based enrichment analysis for genome-wide association studies	22513993	10.1093/bioinformatics/bts191	Cited
Lee, S, Nature Genetics, 2012, Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs	22344220	10.1038/ng.1108	Cited
Levinson, DF, Am J Psychiatry, 2011, Copy number variants in schizophrenia: Confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications	21285140	10.1176/appi.ajp.2010.10060876	Cited
Lichtenstein, P, Lancet, 2009, Common genetic influences for schizophrenia and bipolar disorder: A population-based study of 2 million nuclear families	19150704	10.1016/S0140-6736(09)60072-6	Cited
Lindblad-Toh, K, Nature, 2011, A high-resolution map of human evolutionary constraint using 29 mammals	21993624	10.1038/nature10530	Cited
Liu, JZ, Nature genetics, 2010, Meta-analysis and imputation refines the association of 15q25 with smoking quantity	20418889	10.1038/ng.572	Cited
Ma, D, Annals of human genetics, 2009, A genome-wide association study of autism reveals a common novel risk locus at 5p14.1	19456320	10.1111/j.1469-1809.2009.00523.x	Cited
MacArthur, DG, Science, 2012, A systematic survey of loss-of-function variants in human protein-coding genes	22344438	10.1126/science.1215040	Cited
Malhotra, D et al., Cell, 2012, CNVs: Harbingers of a Rare Variant Revolution in Psychiatric Genetics	22424231	10.1016/j.cell.2012.02.039	Cited
Malhotra, D, Neuron, 2011, High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia	22196331	10.1016/j.neuron.2011.11.007	Cited
Marshall, CR, Am J Hum Genet, 2008, Structural variation of chromosomes in autism spectrum disorder	18252227	10.1016/j.ajhg.2007.12.009	Cited
McCarthy, MI, Nature Reviews Genetics, 2008, Genome-wide association studies for complex traits: consensus, uncertainty and challenges	18398418	10.1038/nrg2344	Cited
McClellan, J et al., JAMA, 2010, Genomic analysis of mental illness: a changing landscape	20571020	10.1001/jama.2010.869	Cited
McKusick, VA, Am J Hum Genet, 2007, Mendelian Inheritance in Man and its online version, OMIM	17357067	10.1086/514346	Cited
McMahon, FJ, Nat Genet, 2010, Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1	20081856	10.1038/ng.523	Cited
McNaughton, D, Neurobiology of aging, 2012, Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series	21193246	10.1016/j.neurobiolaging.2010.10.010	Cited
McQueen, MB, Am J Hum Genet, 2005, Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q	16175504	10.1086/491603	Cited
McQuillin, A, European journal of human genetics : EJHG, 2011, Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample	21206513	10.1038/ejhg.2010.221	Cited
Mefford, HC, PLoS genetics, 2010, Genome-wide copy number variation in epilepsy: novel susceptibility loci in idiopathic generalized and focal epilepsies	20502679	10.1371/journal.pgen.1000962	Cited
Mefford, HC, The New England journal of medicine, 2008, Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes	18784092	10.1056/NEJMoa0805384	Cited
Mi, H, Nucleic acids research, 2010, PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium	20015972	10.1093/nar/gkp1019	Cited
Miller, G, Science, 2010, Is pharma running out of brainy ideas?	20671165	10.1126/science.329.5991.502	Cited
Molecular Psychiatry, 2009, A framework for interpreting genomewide association studies of psychiatric disorders	19002139	10.1038/mp.2008.126	Cited
Molecular Psychiatry, A mega-analysis of genome-wide association studies for major depressive disorder	22472876	10.1038/mp.2012.21	Cited
Moreno-De-Luca, D, American journal of human genetics, 2010, Deletion 17q12 is a recurrent copy number variant that confers high risk of autism and schizophrenia	21055719	10.1016/j.ajhg.2010.10.004	Cited
Munafo, MR et al., Biological psychiatry, 2009, Gene X environment interactions at the serotonin transporter locus	18691701	10.1016/j.biopsych.2008.06.009	Cited
Naj, AC, Nature genetics, 2011, Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer’s disease	21460841	10.1038/ng.801	Cited
Nature Genetics, 2010, Meta-analyses of genome-wide association studies implicate multiple loci for smoking behavior	20418890	10.1038/ng.571	Cited
Nature Genetics, 2011, Genome-wide association study of schizophrenia identifies five novel loci	21926974	10.1038/ng.940	Cited
Nature genetics, 2011, Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4	21926972	10.1038/ng.943	Cited
Nature, 2007, Genome-wide association study of 14, 000 cases of seven common diseases 3, 000 shared controls	17554300	10.1038/nature05911	Cited
Nature, 2008, Greater burden of rare copy number variants in schizophrenia	—	—	—
Nature, 2009, Common polygenic variation contributes to risk of schizophrenia and bipolar disorder	19571811	10.1038/nature08185	Cited
Neale, BM, Journal of the American Academy of Child and Adolescent Psychiatry, 2010, Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder	20732625	10.1016/j.jaac.2010.06.008	Cited
Neale, BM, Nature, 2012, Patterns and rates of exonic de novo mutations in autism spectrum disorders	22495311	10.1038/nature11011	Cited
Ng, MY, Mol Psychiatry, 2009, Meta-analysis of 32 genome-wide linkage studies of schizophrenia	19349958	10.1038/mp.2008.135	Cited
Ng, SB et al., Hum Mol Genet, 2010, Massively parallel sequencing and rare disease	20846941	10.1093/hmg/ddq390	Cited
Nicolae, DL, PLoS genetics, 2010, Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS	20369019	10.1371/journal.pgen.1000888	Cited
Nucleic acids research, 2012, The Gene Ontology: enhancements for 2011	22102568	10.1093/nar/gkr1028	Cited
Orozco, G et al., Hum Mol Genet, 2010, Synthetic associations in the context of genome-wide association scan signals	20805105	10.1093/hmg/ddq368	Cited
Ott, J, Analysis of Human Genetic Linkage, 1999	—	—	—
Owen, MJ et al., Archives of general psychiatry, 2010, Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia	20603448	10.1001/archgenpsychiatry.2010.69	Cited
O’Donovan, M, Nature Genetics, 2008, Identification of novel schizophrenia loci by genome-wide association and follow-up	18677311	10.1038/ng.201	Cited
O’Roak, BJ, Nature, 2012, Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations	22495309	10.1038/nature10989	Cited
Park, YK et al., American journal of public health, 2000, Effectiveness of food fortification in the United States: the case of pellagra	10800421	10.2105/ajph.90.5.727	Cited
Pasaniuc, B, Nature Genetics, Extremely low-coverage sequencing enables cost effective GWAS	—	—	—
Pe’er, I et al., Genet Epidemiol, 2008, Estimation of the multiple testing burden for genomewide association studies of nearly all common variants	18348202	10.1002/gepi.20303	Cited
Pinto, D, Nature, 2010, Functional impact of global rare copy number variation in autism spectrum disorders	20531469	10.1038/nature09146	Primary
Pottier, C, Molecular psychiatry, 2012, High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease	22472873	10.1038/mp.2012.15	Cited
Priebe, L, Molecular psychiatry, 2011, Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder	21358712	10.1038/mp.2011.8	Cited
Raychaudhuri, S, PLoS Genet, 2009, Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions	19557189	10.1371/journal.pgen.1000534	Cited
Raychaudhuri, S, PLoS Genet, 2010, Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function	20838587	10.1371/journal.pgen.1001097	Cited
Rietschel, M, Molecular psychiatry, 2011, Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe	21747397	10.1038/mp.2011.80	Cited
Risch, N, Jama, 2009, Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis	19531786	10.1001/jama.2009.878	Cited
Ropers, HH, Annual review of genomics and human genetics, 2010, Genetics of early onset cognitive impairment	20822471	10.1146/annurev-genom-082509-141640	Cited
Rossin, EJ, PLoS genetics, 2011, Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology	21249183	10.1371/journal.pgen.1001273	Cited
Rovelet-Lecrux, A, Nature genetics, 2006, APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy	16369530	10.1038/ng1718	Cited
Ruano, D, American journal of human genetics, 2010, Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive ability	20060087	10.1016/j.ajhg.2009.12.006	Cited
Rucker, JJ, Molecular psychiatry, 2011, Genome-wide association analysis of copy number variation in recurrent depressive disorder	22042228	10.1038/mp.2011.144	Cited
Ruderfer, DM, Molecular psychiatry, 2011, A family-based study of common polygenic variation and risk of schizophrenia	21483432	10.1038/mp.2011.34	Cited
Rujescu, D, Hum Mol Genet, 2009, Disruption of the neurexin 1 gene is associated with schizophrenia	18945720	10.1093/hmg/ddn351	Cited
Saccone, NL, PLoS genetics, 2010, Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD	20700436	10.1371/journal.pgen.1001053	Primary
Sanders, SJ, Nature, 2012, De novo mutations revealed by whole-exome sequencing are strongly associated with autism	22495306	10.1038/nature10945	Cited
Sanders, SJ, Neuron, 2011, Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism	21658581	10.1016/j.neuron.2011.05.002	Cited
Schumann, G, Proceedings of the National Academy of Sciences of the United States of America, 2011, Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption	21471458	10.1073/pnas.1017288108	Primary
Sebat, J, Science, 2007, Strong association of de novo copy number mutations with autism	17363630	10.1126/science.1138659	Cited
Seshadri, S, JAMA, 2010, Genome-wide analysis of genetic loci associated with Alzheimer disease	20460622	10.1001/jama.2010.574	Cited
Sexually Transmitted Disease Surveillance 2009, 2010	—	—	—
Shi, J, Nature, 2009, Common variants on chromosome 6p22.1 are associated with schizophrenia	19571809	10.1038/nature08192	Cited
Shi, Y, Nature genetics, 2011, Common variants on 8p12 and 1q24.2 confer risk of schizophrenia	22037555	10.1038/ng.980	Cited
Shinawi, M, Journal of medical genetics, 2010, Recurrent reciprocal 16p11.2 rearrangements associated with global developmental delay, behavioural problems, dysmorphism, epilepsy, and abnormal head size	19914906	10.1136/jmg.2009.073015	Cited
Sklar, P, Mol Psychiatry, 2008, Whole-genome association study of bipolar disorder	18317468	10.1038/sj.mp.4002151	Cited
Smrt, RD, Stem Cells, 2010, MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1	20506192	10.1002/stem.431	Cited
Speliotes, EK, Nat Genet, 2010, Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index	20935630	10.1038/ng.686	Cited
Stahl, EA, Nature genetics, 2012, Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis	22446960	10.1038/ng.2232	Cited
Stefansson, H, Nature, 2008, Large recurrent microdeletions associated with schizophrenia	18668039	10.1038/nature07229	Cited
Stefansson, H, Nature, 2009, Common variants conferring risk of schizophrenia	19571808	10.1038/nature08186	Cited
Steinberg, S, Human molecular genetics, 2011, Common variants at VRK2 and TCF4 conferring risk of schizophrenia	21791550	10.1093/hmg/ddr325	Cited
Stergiakouli, E, The American journal of psychiatry, 2011, Investigating the Contribution of Common Genetic Variants to the Risk and Pathogenesis of ADHD	22420046	10.1176/appi.ajp.2011.11040551	Cited
Strittmatter, WJ, Proceedings of the National Academy of Sciences of the United States of America, 1993, Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease	8446617	10.1073/pnas.90.5.1977	Cited
Sullivan, PF et al., Archives of General Psychiatry, 2003, Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies	14662550	10.1001/archpsyc.60.12.1187	Cited
Sullivan, PF, Molecular Psychiatry, 2011, Don’t give up on GWAS	—	—	—
Sullivan, PF, Nature Medicine, 2012, Schizophrenia as a pathway disease	22310687	10.1038/nm.2670	Cited
Sullivan, PF, Neuron, 2010, The Psychiatric GWAS Consortium: big science comes to psychiatry	20955924	10.1016/j.neuron.2010.10.003	Cited
Szatmari, P, Nat Genet, 2007, Mapping autism risk loci using genetic linkage and chromosomal rearrangements	17322880	10.1038/ng1985	Cited
Szulwach, KE, J Cell Biol, 2010, Cross talk between microRNA and epigenetic regulation in adult neurogenesis	20368621	10.1083/jcb.200908151	Cited
Takeuchi, F, Circulation journal : official journal of the Japanese Circulation Society, 2011, Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population	21372407	10.1253/circj.cj-10-0774	Cited
The Global Burden of Disease: 2004 Update, 2008	—	—	—
Thorgeirsson, TE, Nature genetics, 2010, Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior	20418888	10.1038/ng.573	Cited
Thorgeirsson, TE, Nature, 2008, A variant associated with nicotine dependence, lung cancer and peripheral arterial disease	18385739	10.1038/nature06846	Cited
Treusch, S, Science, 2011, Functional links between Abeta toxicity, endocytic trafficking, and Alzheimer’s disease risk factors in yeast	22033521	10.1126/science.1213210	Cited
Trikalinos, TA, Mol Psychiatry, 2006, A heterogeneity-based genome search meta-analysis for autism-spectrum disorders	16189507	10.1038/sj.mp.4001750	Cited
Truong, T, J Natl Cancer Inst, 2010, Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium	20548021	10.1093/jnci/djq178	Cited
Turnbull, C, Nature genetics, 2010, Genome-wide association study identifies five new breast cancer susceptibility loci	20453838	10.1038/ng.586	Cited
Uher, R et al., Molecular psychiatry, 2010, The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update	20029411	10.1038/mp.2009.123	Cited
Vacic, V, Nature, 2011, Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia	21346763	10.1038/nature09884	Cited
Vassos, E, Human molecular genetics, 2010, Penetrance for copy number variants associated with schizophrenia	20587603	10.1093/hmg/ddq259	Cited
Visscher, PM et al., American journal of human genetics, 2012, Five Years of GWAS Discovery	22243964	10.1016/j.ajhg.2011.11.029	Cited
Voight, BF, Nat Genet, 2010, Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis	20581827	10.1038/ng.609	Cited
Voineagu, I, Nature, 2011, Transcriptomic analysis of autistic brain reveals convergent molecular pathology	21614001	10.1038/nature10110	Cited
Vorstman, JA, Mol Psychiatry, 2006, Identification of novel autism candidate regions through analysis of reported cytogenetic abnormalities associated with autism	16205736	10.1038/sj.mp.4001781	Cited
Walsh, T, Science, 2008, Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia	18369103	10.1126/science.1155174	Cited
Wang, K, Molecular psychiatry, 2011, A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa	21079607	10.1038/mp.2010.107	Cited
Wang, K, Nature, 2009, Common genetic variants on 5p14.1 associate with autism spectrum disorders	19404256	10.1038/nature07999	Cited
Waters, KM, PLoS genetics, 2010, Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups	20865176	10.1371/journal.pgen.1001078	Cited
Weiss, LA et al., Nature, 2009, A genome-wide linkage and association scan reveals novel loci for autism	19812673	10.1038/nature08490	Cited
Weiss, LA, New England Journal of Medicine, 2008, Association between microdeletion and microduplication at 16p11.2 and autism	18184952	10.1056/NEJMoa075974	Cited
Willemsen, MH, Journal of medical genetics, 2011, Chromosome 1p21.3 microdeletions comprising DPYD and MIR137 are associated with intellectual disability	22003227	10.1136/jmedgenet-2011-100294	Cited
Williams, HJ, Mol Psychiatry, 2010, Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder	20368704	10.1038/mp.2010.36	Cited
Williams, NM, Lancet, 2010, Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis	20888040	10.1016/S0140-6736(10)61109-9	Cited
Williams, NM, The American journal of psychiatry, 2011, Genome-Wide Analysis of Copy Number Variants in Attention Deficit Hyperactivity Disorder: The Role of Rare Variants and Duplications at 15q13.3	22420048	10.1176/appi.ajp.2011.11060822	Cited
Wray, NR et al., PLoS Biol, 2011, Synthetic associations created by rare variants do not explain most GWAS results	21267061	10.1371/journal.pbio.1000579	Cited
Wray, NR et al., Schizophr Bull, 2010, Narrowing the boundaries of the genetic architecture of schizophrenia	19996148	10.1093/schbul/sbp137	Cited
Wu, EQ, The Journal of clinical psychiatry, 2005, The economic burden of schizophrenia in the United States in 2002	16187769	10.4088/jcp.v66n0906	Cited
Xu, B, Nat Genet, 2008, Strong association of de novo copy number mutations with sporadic schizophrenia	18511947	10.1038/ng.162	Cited
Xu, B, Nature genetics, 2011, Exome sequencing supports a de novo mutational paradigm for schizophrenia	21822266	10.1038/ng.902	Cited
Yang, J et al., Genet Epidemiol, 2010, Comparing apples and oranges: equating the power of case-control and quantitative trait association studies	19918758	10.1002/gepi.20456	Cited
Yang, J, Nat Genet, 2010, Common SNPs explain a large proportion of the heritability for human height	20562875	10.1038/ng.608	Cited
Yaspan, BL et al., Current protocols in human genetics/editorial board, Jonathan L. Haines … [et al.], 2011, Strategies for pathway analysis from GWAS data	21975938	10.1002/0471142905.hg0120s71	Cited
Yue, WH, Nature genetics, 2011, Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2	22037552	10.1038/ng.979	Cited
Zhang, D, Mol Psychiatry, 2009, Singleton deletions throughout the genome increase risk of bipolar disorder	19114987	10.1038/mp.2008.144	Cited
Zhong, L et al., The EMBO journal, 2009, Neurogranin enhances synaptic strength through its interaction with calmodulin	19713936	10.1038/emboj.2009.236	Cited
Zhou, K, American journal of medical genetics. Part B, 2008, Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder	18988193	10.1002/ajmg.b.30878	Cited

In this knowledge base

Title	Year	PMID
Polygenic Risk Score Prediction of Alcohol Dependence Symptoms Across Population-Based and Clinically Ascertained Samples.	2018	29405378
Review: Genetic research on alcohol use outcomes in African American populations: A review of the literature, associated challenges, and implications.	2017	28240821
Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.	2017	28494655
Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.	2016	27166759
Candidate gene-environment interaction research: reflections and recommendations.	2015	25620996
Evaluating historical candidate genes for schizophrenia.	2015	25754081
A genome-wide association study of anorexia nervosa.	2014	24514567
Biological insights from 108 schizophrenia-associated genetic loci.	2014	25056061
DSM-5 cannabis use disorder: a phenotypic and genomic perspective.	2014	24315570
Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants.	2014	24297757
Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.	2014	24828478
Heritability and genomics of gene expression in peripheral blood.	2014	24728292
RNA-Seq reveals novel transcriptional reorganization in human alcoholic brain.	2014	25172479
Synaptic dysregulation in a human iPS cell model of mental disorders.	2014	25132547
A comprehensive family-based replication study of schizophrenia genes.	2013	23894747
Copy number variation: what is it and what has it told us about child psychiatric disorders?	2013	23880486
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.	2013	23933821
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.	2013	23974872
The Minnesota Center for Twin and Family Research genome-wide association study.	2012	23363460

External

Title	Authors	Journal	Year	Link
Association between epigenetic age acceleration and psychiatric disorders: a bidirectional Mendelian randomization study.	Hong Y	—	2026	→
Behavioral differences in cooperation between patients with schizophrenia and control participants.	Sabater-Grande G et al.	—	2026	→
Classification of functional near-infrared spectroscopy (fNIRS) signals in schizophrenia and bipolar disorder using deep learning methods.	Mou L et al.	—	2026	→
eQTL analysis: A bridge from genome to mechanism.	Jia Z et al.	—	2026	→
Genetic Susceptibility to Schizophrenia and the Onset of Brain Developmental Change During Adolescence.	Xu B et al.	—	2026	→
Global lifetime prevalence of schizophrenia: A systematic review and meta-analysis.	Zhang S et al.	—	2026	→
GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy.	Lemke JR et al.	—	2026	→
High-performance graphene field-effect transistor platform for on-site schizophrenia-related biomarkers detection.	Kim SJ et al.	—	2026	→
Mapping the Scientific Landscape of Schizophrenia Genetics (2020-2025): A Bibliometric and Scientometric Study of Global Trends and Collaborations.	Mikaeili N et al.	—	2026	→
Neonatal gut Bifidobacterium associates with indole-3-lactic acid levels in blood and risk of ADHD at age 10.	Widdowson M et al.	—	2026	→
New insights into neurodevelopmental disorders by whole genome sequencing of 100 families from Italy.	Spirito G et al.	—	2026	→
Probiotics, psychobiotics, and postbiotics: a therapeutic modality for the management of schizophrenia.	Ashique S et al.	—	2026	→
Recurrent and Non-Recurrent Copy Number Variants in Native Americans and a Cosmopolitan Sample in Relation to Alcohol Use Disorder and Other Psychiatric Diseases.	Wakil SM et al.	—	2026	→
The role of sex hormones in severe mental illness: A genetic exploration.	Veeneman RR et al.	—	2026	→
Aberrant Short Tandem Repeats: Pathogenicity, Mechanisms, Detection, and Roles in Neuropsychiatric Disorders.	Liu Y et al.	—	2025	→
Absolute and relative risks of mental disorders in families: a Danish register-based study.	Pedersen CB et al.	—	2025	→
Altered inter-subject variability of morphological brain networks and its association with neurotransmitters and gene expression in major depression disorder.	Yao C et al.	—	2025	→
A pathway-informed disease-related gene identification approach and its application to screen novel risk genes for Alzheimer's disease.	Yuan X et al.	—	2025	→
Beyond the Extra X and Y Chromosome: The Contribution of Familial Risk for Psychopathology to the Neurodevelopmental Phenotype of Children With Sex Chromosome Trisomy.	van Rijn S et al.	—	2025	→
Blood lipid profiles and mood disorders: A principal component analysis of UK Biobank data reveals distinct associations with depression and bipolar disorder.	Liu X et al.	—	2025	→
Body fluid biomarkers and psychosis risk in The Accelerating Medicines Partnership® Schizophrenia Program: design considerations.	Perkins DO et al.	—	2025	→
Brain region and cell specificity of <i>B4GALT6</i> in mice with depressive-like behavior: A pilot study.	Zhang SN et al.	—	2025	→
Cell-type specific global reprogramming of the transcriptome and epigenome in induced neurons with the 16p11.2 neuropsychiatric CNVs.	Ward TR et al.	—	2025	→
Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids.	Dony L et al.	—	2025	→
Decoding the genomic symphony: unravelling brain disorders through data integration and machine learning.	Bracher-Smith M et al.	—	2025	→
Dermatoglyphics and schizophrenia: A comprehensive review of neurodevelopmental biomarkers.	Bou Farah E et al.	—	2025	→
Disorder at the Synapse: How the Active Inference Framework Unifies Competing Perspectives on Depression.	Davey CG et al.	—	2025	→
DNA methylation profiles of transgenerational rat hyperactivity primed by silver nanoparticles: Comparison with valproate model rats of autism.	Ishido M et al.	—	2025	→
Effects of Shared and Nonshared Schizophrenia and Bipolar Disorder Alleles on Cognition and Educational Attainment in the UK Biobank.	Richards AL et al.	—	2025	→
Elucidating the interplay between gut microbiota and autism spectrum disorder. New insights and therapeutic perspectives.	Mavridou M et al.	—	2025	→
Ethical Considerations in Psychiatric Genomics.	Stein DJ et al.	—	2025	→
Genetics of Suicide.	Khalil M et al.	—	2025	→
Genomics of schizophrenia, bipolar disorder and major depressive disorder.	Owen MJ et al.	—	2025	→
HPA-axis multilocus genetic interaction with stress life events in predicting changes in adolescent suicidal ideation.	Zhao X et al.	—	2025	→
Independent, Multiplicative, and Cumulative Effects of Recent Stressful Life Events and Adverse Childhood Events on Depressive Symptoms among College Students: Moderation by the HPA-axis Multilocus Genetic Variation.	Yang Y et al.	—	2025	→
Integrative multi-omics data from early development to identify the genes and cell types underlying attention-deficit/hyperactivity disorder.	Jiao S et al.	—	2025	→
Kinship Decouple and Phenotype Selection (KDPS): a tool for phenotype-aware decoupling of related subjects.	Gu W et al.	—	2025	→
Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response.	Skelly DA et al.	—	2025	→
Maternal ADHD symptom severity and mother-child dyadic synchrony: an experimental study.	Yaniv-Rosenfeld A et al.	—	2025	→
Molecular Signatures of Schizophrenia and Insights into Potential Biological Convergence.	Saada M et al.	—	2025	→
Neurobiological correlates of schizophrenia-specific and highly pleiotropic genetic risk scores for neuropsychiatric disorders.	Federmann LM et al.	—	2025	→
[Physical exposures in psychiatry: the promises of the PEPR "PROPSY"].	Pignon B et al.	—	2025	→
Plant-derived nanovesicles: Promising therapeutics and drug delivery nanoplatforms for brain disorders.	Wang R et al.	—	2025	→
Polygenic and Polyenvironment Interplay in Schizophrenia-Spectrum Disorder and Affective Psychosis; the EUGEI First Episode Study.	Rodriguez V et al.	—	2025	→
Psychiatric Genetics in Clinical Practice: Essential Knowledge for Mental Health Professionals.	Besterman AD et al.	—	2025	→
Schizotypal Traits in Children with Autism Spectrum Disorder and the Impact on Social, Emotional and Behavioral Functioning.	Tagkouli E et al.	—	2025	→
The effects of childhood maltreatment, recent interpersonal and noninterpersonal stress, and HPA-axis multilocus genetic variation on prospective changes in adolescent depressive symptoms: A multiwave longitudinal study.	Sun K et al.	—	2025	→
The "five-star matrix" for patient-centric drug discovery and development in neuroscience.	Pähler A et al.	—	2025	→
The Intricate Relationship of Trk Receptors in Brain Diseases and Disorders.	Dahiya S et al.	—	2025	→
The regulatory variant rs1950834 confers the risk of depressive disorder by reducing LRFN5 expression.	Luan D et al.	—	2025	→
Widening disparities in all-cause and despair-related mortality among Swedish youths: Disentangling selection and causation.	Högberg B et al.	—	2025	→
Altered pubertal timing in 7q11.23 copy number variations and associated genetic mechanisms.	Wei SM et al.	—	2024	→
A survey in Austria supports the significance of genetic counseling and pharmacogenetic testing for mental illness.	Aschauer E et al.	—	2024	→
Causal effects of various types of physical activities on psychiatric disorders: a Mendelian randomization study.	Yu L et al.	—	2024	→
Current progress in understanding schizophrenia using genomics and pluripotent stem cells: A meta-analytical overview.	Choudhary A et al.	—	2024	→
Detection and analysis of complex structural variation in human genomes across populations and in brains of donors with psychiatric disorders.	Zhou B et al.	—	2024	→
Distinct Volume Alterations of Thalamic Nuclei Across the Schizophrenia Spectrum.	Thalhammer M et al.	—	2024	→
Facile, eco-friendly and sensitive fluorimetric approach for detection of chlorpromazine: Application in biological fluids and tablet formulations as well as greenness evaluation of the analytical method.	Mostafa IM et al.	—	2024	→
[From generation to generation: mechanisms of risk transmission of parental mental illness in early childhood].	Zietlow AL et al.	—	2024	→
Genetic influences on depression and selection into adverse life experiences.	Rauf T et al.	—	2024	→
Genomic Machine Learning Meta-regression: Insights on Associations of Study Features With Reported Model Performance.	Barnett EJ et al.	—	2024	→
Human olfactory neurosphere-derived cells: a unified tool for neurological disease modelling and neurotherapeutic applications.	Irfan S et al.	—	2024	→
Nutrigenomics and neurological disorders: exploring diet-brain interactions for cognitive health.	Waheed A et al.	—	2024	→
Prenatal antidepressant exposure and the risk of decreased gestational age and lower birthweight: A polygenic score approach to investigate confounding by indication.	Rommel AS et al.	—	2024	→
Risk and protective factors for severe mental disorders in Asia.	Rami FZ et al.	—	2024	→
Specifying the timescale of early life unpredictability helps explain the development of internalising and externalising behaviours.	Farkas BC et al.	—	2024	→
The Association Between Prolactin Levels and Cognitive Function in Female Patients With Severe Mental Disorders.	Xu Y et al.	—	2024	→
Very Early-Onset Schizophrenia with Accompanying Obsessive-Compulsive Symptoms: A Case Report of a Female with 16p13.11 Duplication.	Kızıltan K et al.	—	2024	→
Brain-derived neurotrophic factor (BDNF) in schizophrenia research: a quantitative review and future directions.	Ahmad R et al.	—	2023	→
Brain-derived neurotrophic factor Val66Met polymorphism moderates the relationship between impulsivity, negative emotions, and binge drinking intensity in university students.	Benzerouk F et al.	—	2023	→
Childhood parenting and adolescent internalizing and externalizing symptoms: Moderation by multilocus hypothalamic-pituitary-adrenal axis-related genetic variation.	Cao C et al.	—	2023	→
Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study.	Lu T et al.	—	2023	→
Cognitive biases as an adaptive strategy in autism and schizophrenia spectrum: the compensation perspective on neurodiversity.	Rządeczka M et al.	—	2023	→
Common genetic and environmental risk for personality disorders and psychotic-like experiences in young adult twins.	Tesli M et al.	—	2023	→
Common susceptibility variants of <i>KDR</i> and <i>IGF-1R</i> are associated with poststroke depression in the Chinese population.	Yue Y et al.	—	2023	→
Comparative neurogenetics of dog behavior complements efforts towards human neuropsychiatric genetics.	Morrill K et al.	—	2023	→
Current status, challenges and future prospects in computational psychiatry: a narrative review.	Vasilchenko KF et al.	—	2023	→
Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood.	Askeland RB et al.	—	2023	→
Editorial: Community series in genetic mechanisms of biomarkers in schizophrenia, bipolar disorder and depression, volume II.	Yin Y et al.	—	2023	→
Emerging role of the host microbiome in neuropsychiatric disorders: overview and future directions.	Hashimoto K	—	2023	→
Epigenetics in Neurological and Psychiatric Disorders: A Comprehensive Review of Current Understanding and Future Perspectives.	Grezenko H et al.	—	2023	→
Exploring the Hypothesis of a Schizophrenia and Bipolar Disorder Continuum: Biological, Genetic and Pharmacologic Data.	de Sousa TR et al.	—	2023	→
Family-based analysis of the contribution of rare and common genetic variants to school performance in schizophrenia.	Rammos A et al.	—	2023	→
Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis: evidence from population sample stratified for polygenic risk.	Dimitriadis SI et al.	—	2023	→
Gut microbiome at the crossroad of genetic variants and behavior disorders.	Cheng L et al.	—	2023	→
How can childhood maltreatment affect post-traumatic stress disorder in adult: Results from a composite null hypothesis perspective of mediation analysis.	Xu H et al.	—	2023	→
Long-term exposure to ambient air pollution, genetic susceptibility, and the incidence of bipolar disorder: A prospective cohort study.	Li D et al.	—	2023	→
Massively parallel functional dissection of schizophrenia-associated noncoding genetic variants.	Rummel CK et al.	—	2023	→
Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatric bipolar disorder.	Yang G et al.	—	2023	→
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications.	Andreassen OA et al.	—	2023	→
Proteome-wide Mendelian randomization reveals the causal effects of immune-related plasma proteins on psychiatric disorders.	Dang X et al.	—	2023	→
Research hotspots and trends in the relationship between genetics and major depressive disorder: A scientometric analysis from 2003 to 2023.	Zhao Z et al.	—	2023	→
Sex/gender differences in children with autism spectrum disorder: A brief overview on epidemiology, symptom profile, and neuroanatomy.	Calderoni S	—	2023	→
Single-Cell RNA Sequencing and Its Applications in the Study of Psychiatric Disorders.	Antunes ASLM et al.	—	2023	→
The relative and interactive impact of multiple risk factors in schizophrenia spectrum disorders: a combined register-based and clinical twin study.	Lemvigh C et al.	—	2023	→
The shared genetic architecture of suicidal behaviour and psychiatric disorders: A genomic structural equation modelling study.	Kootbodien T et al.	—	2023	→
Assessing the joint effects of brain aging and gut microbiota on the risks of psychiatric disorders.	Zhang H et al.	—	2022	→
Association of bisphenol A, bisphenol F, and bisphenol S with ADHD symptoms in children.	Kim JI et al.	—	2022	→
Associations between Omega-3 Index, Dopaminergic Genetic Variants and Aggressive and Metacognitive Traits: A Study in Adult Male Prisoners.	Fernandez F et al.	—	2022	→
Associations between out-of-home care and mental health disorders within and across generations in a Swedish birth cohort.	Straatmann VS et al.	—	2022	→
Brain gyrification in bipolar disorder: a systematic review of neuroimaging studies.	Miola A et al.	—	2022	→
Catalytic Reaction Model of Suicide.	McPherson P et al.	—	2022	→
Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia.	Farrelly LA et al.	—	2022	→
Cis-regulatory hubs: a new 3D model of complex disease genetics with an application to schizophrenia.	Mangnier L et al.	—	2022	→
Clinical research diagnostic criteria for bipolar illness (CRDC-BP): rationale and validity.	Ghaemi SN et al.	—	2022	→
CRISPR/Cas-Based Approaches to Study Schizophrenia and Other Neurodevelopmental Disorders.	Kurishev AO et al.	—	2022	→
Disrupted <i>Cacna1c</i> gene expression perturbs spontaneous Ca<sup>2+</sup> activity causing abnormal brain development and increased anxiety.	Smedler E et al.	—	2022	→
Distinctively lower DISC1 mRNA levels in patients with schizophrenia, especially in those with higher positive, negative, and depressive symptoms.	Chen YM et al.	—	2022	→
DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses.	Shen X et al.	—	2022	→
Early manifestations of genetic risk for neurodevelopmental disorders.	Askeland RB et al.	—	2022	→
Exome sequencing of Japanese schizophrenia multiplex families supports the involvement of calcium ion channels.	Toyama M et al.	—	2022	→
Familial co-aggregation and shared heritability between depression, anxiety, obesity and substance use.	Wang R et al.	—	2022	→
Gene expression changes following chronic antipsychotic exposure in single cells from mouse striatum.	Abrantes A et al.	—	2022	→
Genetic Polymorphisms in miR-137 and Its Target Genes, TCF4 and CACNA1C, Contribute to the Risk of Bipolar Disorder: A Preliminary Case-Control Study and Bioinformatics Analysis.	Mokhtari MA et al.	—	2022	→
Genetics in the ADHD Clinic: How Can Genetic Testing Support the Current Clinical Practice?	Balogh L et al.	—	2022	→
Granulocyte colony-stimulating factor has a sex-dependent positive effect in the maternal immune activation-induced autism model.	Durankuş F et al.	—	2022	→
Histone Acetylation and Methylation Underlie Oligodendroglial and Myelin Susceptibility in Schizophrenia.	Li M et al.	—	2022	→
Identifying pleiotropic genes for complex phenotypes with summary statistics from a perspective of composite null hypothesis testing.	Wang T et al.	—	2022	→
Impaired migration of autologous induced neural stem cells from patients with schizophrenia and implications for genetic risk for psychosis.	Lee J et al.	—	2022	→
Mapping the genetic architecture of cortical morphology through neuroimaging: progress and perspectives.	van der Meer D et al.	—	2022	→
Meals, Microbiota and Mental Health in Children and Adolescents (MMM-Study): A protocol for an observational longitudinal case-control study.	Asbjornsdottir B et al.	—	2022	→
Meta-analytical transdiagnostic neural correlates in common pediatric psychiatric disorders.	Dugré JR et al.	—	2022	→
Multi-site harmonization of MRI data uncovers machine-learning discrimination capability in barely separable populations: An example from the ABIDE dataset.	Saponaro S et al.	—	2022	→
Neurobiological Highlights of Cognitive Impairment in Psychiatric Disorders.	Morozova A et al.	—	2022	→
Neurotrophin Crosstalk in the Etiology and Treatment of Neuropsychiatric and Neurodegenerative Disease.	Joshi R et al.	—	2022	→
Overview of CAPICE-Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe-an EU Marie Skłodowska-Curie International Training Network.	Rajula HSR et al.	—	2022	→
Polygenic risk scores: An overview from bench to bedside for personalised medicine.	Cross B et al.	—	2022	→
Predicting the emergence of full-threshold bipolar I, bipolar II and psychotic disorders in young people presenting to early intervention mental health services.	Carpenter JS et al.	—	2022	→
Preliminary studies on apparent mendelian psychotic disorders in consanguineous families.	Kanwal A et al.	—	2022	→
Prevalence and comorbidity of psychiatric disorders among treatment-seeking elite athletes and high-performance coaches.	Åkesdotter C et al.	—	2022	→
Subchronic PCP effects on DNA methylation and protein expression of NMDA receptor subunit genes in the prefrontal cortex and hippocampus of female rats.	Loureiro CM et al.	—	2022	→
The association of prenatal and childhood pyrethroid pesticide exposure with school-age ADHD traits.	Lee KS et al.	—	2022	→
The Contribution of the Rüdin School to Psychiatric Genetics: The Light and the Darkness.	Owen MJ	—	2022	→
The D2R-DISC1 protein complex and associated proteins are altered in schizophrenia and normalized with antipsychotic treatment.	Wang J et al.	—	2022	→
The Long Non-Coding RNA <i>GOMAFU</i> in Schizophrenia: Function, Disease Risk, and Beyond.	Zakutansky PM et al.	—	2022	→
The role of adolescent social relationships in promoting alcohol resistance: Interrupting the intergenerational transmission of alcohol misuse.	Stephenson M et al.	—	2022	→
Trends in big data analyses by multicenter collaborative translational research in psychiatry.	Onitsuka T et al.	—	2022	→
Using Crisis Theory in Dealing With Severe Mental Illness-A Step Toward Normalization?	Baumgardt J et al.	—	2022	→
Using major depression polygenic risk scores to explore the depressive symptom continuum.	Jermy BS et al.	—	2022	→
A comprehensive gene-centric pleiotropic association analysis for 14 psychiatric disorders with GWAS summary statistics.	Lu H et al.	—	2021	→
A missense variant in NDUFA6 confers schizophrenia risk by affecting YY1 binding and NAGA expression.	Li Y et al.	—	2021	→
A new 3-hit mouse model of schizophrenia built on genetic, early and late factors.	Bouet V et al.	—	2021	→
Anxiety-related defensive behavioral responses in mice selectively bred for High and Low Activity.	Booher WC et al.	—	2021	→
A Recessively Inherited Risk Locus on Chromosome 13q22-31 Conferring Susceptibility to Schizophrenia.	Mahmood T et al.	—	2021	→
Assessing Stakeholder Perceptions of the Utility of Genetic Information for the Clinical Care of Mental Health Disorders: We Have a Will but Need to See the Way.	Bourdon JL et al.	—	2021	→
Association of etiological factors across the extreme end and continuous variation in disordered eating in female Swedish twins.	Dinkler L et al.	—	2021	→
Associations of Genetic Polymorphisms and Neuroimmune Markers With Some Parameters of Frontal Lobe Dysfunction in Schizophrenia.	Morozova A et al.	—	2021	→
Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease.	Sidhaye J et al.	—	2021	→
Characterisation of Neurospheres-Derived Cells from Human Olfactory Epithelium.	Zelenova EA et al.	—	2021	→
Chromatin Profiling Techniques: Exploring the Chromatin Environment and Its Contributions to Complex Traits.	Chawla A et al.	—	2021	→
Comorbidity between Alzheimer's disease and major depression: a behavioural and transcriptomic characterization study in mice.	Martín-Sánchez A et al.	—	2021	→
Copy Number Variants and Polygenic Risk Scores Predict Need of Care in Autism and/or ADHD Families.	LaBianca S et al.	—	2021	→
Copy Number Variation Identification on 3,800 Alzheimer's Disease Whole Genome Sequencing Data from the Alzheimer's Disease Sequencing Project.	Lee WP et al.	—	2021	→
Early Detection and Prevention of Schizophrenic Psychosis-A Review.	Westhoff MLS et al.	—	2021	→
Editorial: Genetic Mechanisms of Biomarkers in Schizophrenia, Bipolar Disorder and Depression.	Tang Y et al.	—	2021	→
Effects of polygenic risk score, childhood trauma and resilience on depressive symptoms in Chinese adolescents in a three-year cohort study.	Shao N et al.	—	2021	→
Elevated common variant genetic risk for tourette syndrome in a densely-affected pedigree.	Halvorsen M et al.	—	2021	→
Elucidation of molecular pathogenesis and drug development for psychiatric disorders from rare disease-susceptibility variants.	Kimura H et al.	—	2021	→
Ethical concerns relating to genetic risk scores for suicide.	Docherty A et al.	—	2021	→
Explaining the missing heritability of psychiatric disorders.	Owen MJ et al.	—	2021	→
Exploring the genetic heterogeneity in major depression across diagnostic criteria.	Jermy BS et al.	—	2021	→
Generative network models of altered structural brain connectivity in schizophrenia.	Zhang X et al.	—	2021	→
Genetic and functional analysis reveals <i>TENM4</i> contributes to schizophrenia.	Yi X et al.	—	2021	→
Genetic correlates of socio-economic status influence the pattern of shared heritability across mental health traits.	Marees AT et al.	—	2021	→
Genetic Overlap Profiles of Cognitive Ability in Psychotic and Affective Illnesses: A Multisite Study of Multiplex Pedigrees.	Knowles EEM et al.	—	2021	→
Genetic Testing in Neurodevelopmental Disorders.	Savatt JM et al.	—	2021	→
Harmonizing the Neurobiology and Treatment of Obsessive-Compulsive Disorder.	Goodman WK et al.	—	2021	→
Histamine H<sub>1</sub> receptor deletion in cholinergic neurons induces sensorimotor gating ability deficit and social impairments in mice.	Cheng L et al.	—	2021	→
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease.	Herborg F et al.	—	2021	→
<i>DRD1</i> and <i>DRD2</i> Receptor Polymorphisms: Genetic Neuromodulation of the Dopaminergic System as a Risk Factor for ASD, ADHD and ASD/ADHD Overlap.	Mariggiò MA et al.	—	2021	→
Induced pluripotent stem cells for 2D and 3D modelling the biological basis of schizophrenia and screening possible therapeutics.	Tomaskovic-Crook E et al.	—	2021	→
In-Silico Study of Immune System Associated Genes in Case of Type-2 Diabetes With Insulin Action and Resistance, and/or Obesity.	Eldakhakhny BM et al.	—	2021	→
Intergenerational transmission of out-of-home care and the role of mental health problems: Findings from Stockholm birth cohort multigenerational study.	Straatmann VS et al.	—	2021	→
Investigating attention-deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life?	Riglin L et al.	—	2021	→
Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa.	Adams DM et al.	—	2021	→
In-vivo design feedback and perceived utility of a genetically-informed smoking risk tool among current smokers in the community.	Bourdon JL et al.	—	2021	→
Knock-Down of Hippocampal DISC1 in Immune-Challenged Mice Impairs the Prefrontal-Hippocampal Coupling and the Cognitive Performance Throughout Development.	Xu X et al.	—	2021	→
Military veterans with and without post-traumatic stress disorder: results from a chronic pain management programme.	Van Der Merwe J et al.	—	2021	→
Monoaminergic Multilocus Genetic Variants Interact with Stressful Life Events in Predicting Changes in Adolescent Anxiety Symptoms: A One-year Longitudinal Study.	Cao C et al.	—	2021	→
Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia.	Yamamoto K et al.	—	2021	→
Network-based analysis on genetic variants reveals the immunological mechanism underlying Alzheimer's disease.	Guo P et al.	—	2021	→
Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia.	Lencz T et al.	—	2021	→
Nutraceutical regulation of miRNAs involved in neurodegenerative diseases and brain cancers.	Ghosh S et al.	—	2021	→
Optogenetic Approaches to Understand the Neural Circuit Mechanism of Social Deficits Seen in Autism Spectrum Disorders.	Nakai N et al.	—	2021	→
Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants.	Saarentaus EC et al.	—	2021	→
Polygenic risk score as clinical utility in psychiatry: a clinical viewpoint.	Ikeda M et al.	—	2021	→
Probing the <i>VIPR2</i> Microduplication Linkage to Schizophrenia in Animal and Cellular Models.	Ago Y et al.	—	2021	→
Proteome-wide Association Study Provides Insights Into the Genetic Component of Protein Abundance in Psychiatric Disorders.	Liu J et al.	—	2021	→
Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.	Zhan L et al.	—	2021	→
Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations.	Rees E et al.	—	2021	→
Serotonin 2A receptors and cannabinoids.	Ibarra-Lecue I et al.	—	2021	→
Stress sensitization to depression following childhood adversity: Moderation by HPA axis and serotonergic multilocus profile scores.	Starr LR et al.	—	2021	→
Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders.	Wang X et al.	—	2021	→
Swedish large-scale schizophrenia study: Why do patients and healthy controls participate?	Dufva YE et al.	—	2021	→
Two screening instruments for collecting alcohol-related information from expectant mothers and fathers: Testing the reliability of the Parent Alcohol Screening Questionnaire and the Social Support for an Alcohol-Free Pregnancy Questionnaire.	Högberg H et al.	—	2021	→
Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism.	Takeuchi S et al.	—	2020	→
A dominant-negative variant in the dopamine transporter PDZ-binding motif is linked to parkinsonism and neuropsychiatric disease	Herborg F et al.	—	2020	—
Advanced paternal age as a risk factor for neurodevelopmental disorders: a translational study.	Krug A et al.	—	2020	→
A genome-wide multiphenotypic association analysis identified candidate genes and gene ontology shared by four common risky behaviors.	Ye J et al.	—	2020	→
A joint study of whole exome sequencing and structural MRI analysis in major depressive disorder.	Zhang Y et al.	—	2020	→
An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study.	Dwyer DB et al.	—	2020	→
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition.	Writing Committee for the ENIGMA-CNV Working Group et al.	—	2020	→
Association of FKBP5 genotype with depressive symptoms in patients with coronary heart disease: a prospective study.	Brandt J et al.	—	2020	→
Astrocyte DISC1 contributes to cognitive function in a brain region-dependent manner.	Shevelkin AV et al.	—	2020	→
Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease.	Hollander JA et al.	—	2020	→
Blood Transcriptome Response to Environmental Metal Exposure Reveals Potential Biological Processes Related to Alzheimer's Disease.	Krauskopf J et al.	—	2020	→
Brief Report: Genetic Links Between Autism and Suicidal Behavior-A Preliminary Investigation.	DiBlasi E et al.	—	2020	→
Causes and Consequences of Diagnostic Heterogeneity in Depression: Paths to Discovering Novel Biological Depression Subtypes.	Lynch CJ et al.	—	2020	→
Characterization of Single Gene Copy Number Variants in Schizophrenia.	Szatkiewicz JP et al.	—	2020	→
CNVs and Chromosomal Aneuploidy in Patients With Early-Onset Schizophrenia and Bipolar Disorder: Genotype-Phenotype Associations.	Gregoric Kumperscak H et al.	—	2020	→
Cohort profile: the Brain and Mind Centre <i>Optymise</i> cohort: tracking multidimensional outcomes in young people presenting for mental healthcare.	Carpenter JS et al.	—	2020	→
Critical review of the evidence base regarding theories conceptualising the aetiology of psychosis.	Riley M	—	2020	→
De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia.	Rees E et al.	—	2020	→
Development of Classification Models for the Prediction of Alzheimer's Disease Utilizing Circulating Sex Hormone Ratios.	Hayashi K et al.	—	2020	→
Evaluating the Impact of Nonrandom Mating: Psychiatric Outcomes Among the Offspring of Pairs Diagnosed With Schizophrenia and Bipolar Disorder.	Nordsletten AE et al.	—	2020	→
Four Actionable Bottlenecks and Potential Solutions to Translating Psychiatric Genetics Research: An Expert Review.	Bourdon JL et al.	—	2020	→
From Maternal Diet to Neurodevelopmental Disorders: A Story of Neuroinflammation.	Bordeleau M et al.	—	2020	→
Functional genomics links genetic origins to pathophysiology in neurodegenerative and neuropsychiatric disease.	Wamsley B et al.	—	2020	→
Gene expression changes associated with trajectories of psychopathology in a longitudinal cohort of children and adolescents.	Ota VK et al.	—	2020	→
Gene-set Enrichment with Mathematical Biology (GEMB).	Cochran AL et al.	—	2020	→
Genetics of ADHD: What Should the Clinician Know?	Grimm O et al.	—	2020	→
Genetic susceptibility, inflammation and specific types of depressive symptoms: evidence from the English Longitudinal Study of Ageing.	Frank P et al.	—	2020	→
Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder.	Rao S et al.	—	2020	→
Hidden proteome of synaptic vesicles in the mammalian brain.	Taoufiq Z et al.	—	2020	→
Human pluripotent stem cell-derived models and drug screening in CNS precision medicine.	Silva MC et al.	—	2020	→
Individual differences <i>v.</i> the average patient: mapping the heterogeneity in ADHD using normative models.	Wolfers T et al.	—	2020	→
Interaction between adverse childhood experiences and polygenic risk in patients with bipolar disorder.	Park YM et al.	—	2020	→
In vitro modeling for inherited neurological diseases using induced pluripotent stem cells: from 2D to organoid.	Nam KH et al.	—	2020	→
Maternal antenatal depression and child mental health: Moderation by genomic risk for attention-deficit/hyperactivity disorder.	Chen LM et al.	—	2020	→
Mental health is biological health: Why tackling "diseases of the mind" is an imperative for biological anthropology in the 21st century.	Syme KL et al.	—	2020	→
Multiple Rare Risk Coding Variants in Postsynaptic Density-Related Genes Associated With Schizophrenia Susceptibility.	Hu TM et al.	—	2020	→
Neuronal defects in a human cellular model of 22q11.2 deletion syndrome.	Khan TA et al.	—	2020	→
No evidence for a relationship between MHC heterozygosity and life history strategy in a sample of North American undergraduates.	Murray DR et al.	—	2020	→
Nordic OCD & Related Disorders Consortium: Rationale, design, and methods.	Mataix-Cols D et al.	—	2020	→
Overdispersed gene expression in schizophrenia.	Huang G et al.	—	2020	→
Parallel Social Information Processing Circuits Are Differentially Impacted in Autism.	Lewis EM et al.	—	2020	→
PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia.	Monroe TO et al.	—	2020	→
Pharmacotherapies and personalized medicine for alcohol use disorder: a review.	Lohoff FW	—	2020	→
Psychiatric genomics researchers' perspectives on best practices for returning results to individual participants.	Kostick K et al.	—	2020	→
Psychiatric Polygenic Risk Scores as Predictor for Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in a Clinical Child and Adolescent Sample.	Jansen AG et al.	—	2020	→
Rare copy number variants in individuals at clinical high risk for psychosis: Enrichment of synaptic/brain-related functional pathways.	Jagannath V et al.	—	2020	→
Rare single-nucleotide DAB1 variants and their contribution to Schizophrenia and autism spectrum disorder susceptibility.	Nawa Y et al.	—	2020	→
Recent Progress on Relevant microRNAs in Autism Spectrum Disorders.	Wu X et al.	—	2020	→
Regulatory mechanisms of major depressive disorder risk variants.	Li S et al.	—	2020	→
RICOPILI: Rapid Imputation for COnsortias PIpeLIne.	Lam M et al.	—	2020	→
Role of Infection, Autoimmunity, Atopic Disorders, and the Immune System in Schizophrenia: Evidence from Epidemiological and Genetic Studies.	Benros ME et al.	—	2020	→
Sharing of Genetic Association Signals by Age-Related Macular Degeneration and Alzheimer's Disease at Multiple Levels.	Tan H et al.	—	2020	→
Specificity and Continuity of Schizophrenia and Bipolar Disorder: Relation to Biomarkers.	Yamada Y et al.	—	2020	→
SZDB2.0: an updated comprehensive resource for schizophrenia research.	Wu Y et al.	—	2020	→
The complex neurobiology of resilient functioning after childhood maltreatment.	Ioannidis K et al.	—	2020	→
The efficacy and safety of sulforaphane as an adjuvant in the treatment of bipolar depressive disorder: Study protocol for a randomized, double-blinded, placebo-controlled, parallel-group clinical trial.	Wu C et al.	—	2020	→
The stress-Wnt-signaling axis: a hypothesis for attention-deficit hyperactivity disorder and therapy approaches.	Yde Ohki CM et al.	—	2020	→
Transcriptome analysis of fibroblasts from schizophrenia patients reveals differential expression of schizophrenia-related genes.	Etemadikhah M et al.	—	2020	→
Translating insights from neuropsychiatric genetics and genomics for precision psychiatry.	Rees E et al.	—	2020	→
Turning strains into strengths for understanding psychiatric disorders.	Moore SJ et al.	—	2020	→
Wnt receptor gene <i>FZD1</i> was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort.	Liu X et al.	—	2020	→
Adolescent Δ<sup>9</sup>-Tetrahydrocannabinol Exposure and Astrocyte-Specific Genetic Vulnerability Converge on Nuclear Factor-κB-Cyclooxygenase-2 Signaling to Impair Memory in Adulthood.	Jouroukhin Y et al.	—	2019	→
A Frameshift Variant in the CHST9 Gene Identified by Family-Based Whole Genome Sequencing Is Associated with Schizophrenia in Chinese Population.	Chen J et al.	—	2019	→
Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population.	Musliner KL et al.	—	2019	→
Associations between schizophrenia genetic risk, anxiety disorders and manic/hypomanic episode in a longitudinal population cohort study.	Richards A et al.	—	2019	→
Biological and practical implications of genome-wide association study of schizophrenia using Bayesian variable selection.	Rowe B et al.	—	2019	→
Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia.	de Vrij FM et al.	—	2019	→
Chromatin Remodeling Complex NuRD in Neurodevelopment and Neurodevelopmental Disorders.	Hoffmann A et al.	—	2019	→
Common genetic variants have associations with human cortical brain regions and risk of schizophrenia.	Bi X et al.	—	2019	→
Convergent Evidence That ZNF804A Is a Regulator of Pre-messenger RNA Processing and Gene Expression.	Chapman RM et al.	—	2019	→
Convolutional neural network model to predict causal risk factors that share complex regulatory features.	Lee T et al.	—	2019	→
Current Understanding of Gut Microbiota in Mood Disorders: An Update of Human Studies.	Huang TT et al.	—	2019	→
Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders.	Sullivan PF et al.	—	2019	→
Exome sequencing of sporadic childhood-onset schizophrenia suggests the contribution of X-linked genes in males.	Ambalavanan A et al.	—	2019	→
FKBP5 Gene Variants May Modulate Depressive Features in Bipolar Disorder.	Calabrò M et al.	—	2019	→
Genetics and genetic counseling in psychiatry: Results from an opinion survey of professionals and users.	Martorell L et al.	—	2019	→
Genetics of Eating Disorders: What the Clinician Needs to Know.	Bulik CM et al.	—	2019	→
Genetic variants in major depressive disorder: From pathophysiology to therapy.	Gonda X et al.	—	2019	→
Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts.	Zhang X et al.	—	2019	→
Genotype Variations of rs13381800 in TCF4 Gene and rs17039988 in NRXN1 Gene among a Sample of Iranian Patients with Schizophrenia.	Agahi M et al.	—	2019	→
Glutamate hypothesis in schizophrenia.	Uno Y et al.	—	2019	→
GWAS and Beyond: Using Omics Approaches to Interpret SNP Associations.	Chen HH et al.	—	2019	→
How genome-wide association studies (GWAS) made traditional candidate gene studies obsolete.	Duncan LE et al.	—	2019	→
<i>De novo</i> Mutations From Whole Exome Sequencing in Neurodevelopmental and Psychiatric Disorders: From Discovery to Application.	Wang W et al.	—	2019	→
Imaging Genetics Towards a Refined Diagnosis of Schizophrenia.	Jiang W et al.	—	2019	→
In search of disorders: internalizing symptom networks in a large clinical sample.	McElroy E et al.	—	2019	→
Integrating Genomics into Psychiatric Practice: Ethical and Legal Challenges for Clinicians.	Ward ET et al.	—	2019	→
Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder.	Li H et al.	—	2019	→
<i>TCF4</i> and <i>COL8A2</i> Gene Polymorphism Screening in a Greek Population of Late-onset Fuchs Endothelial Corneal Dystrophy.	Moschos MM et al.	—	2019	→
Lack of circulating toxoplasma gondii DNA in seropositive patients with bipolar or schizophrenia spectrum disorders.	Galli L et al.	—	2019	→
Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior.	Ganna A et al.	—	2019	→
Laser capture microdissection-targeted mass spectrometry: a method for multiplexed protein quantification within individual layers of the cerebral cortex.	MacDonald ML et al.	—	2019	→
MeCP2 Dysfunction in Rett Syndrome and Neuropsychiatric Disorders.	Chin EWM et al.	—	2019	→
Mega-analysis of Odds Ratio: A Convergent Method for a Deep Understanding of the Genetic Evidence in Schizophrenia.	Jia P et al.	—	2019	→
MicroRNA Cross-Involvement in Autism Spectrum Disorders and Atopic Dermatitis: A Literature Review.	Tonacci A et al.	—	2019	→
Neuronal migration in the CNS during development and disease: insights from <i>in vivo</i> and <i>in vitro</i> models.	Buchsbaum IY et al.	—	2019	→
Omega-3 polyunsaturated fatty acids and psychological intervention for workers with mild to moderate depression: A double-blind randomized controlled trial.	Tayama J et al.	—	2019	→
Pathological ATPergic Signaling in Major Depression and Bipolar Disorder.	Illes P et al.	—	2019	→
Polygenic liability for schizophrenia predicts shifting-specific executive function deficits and tobacco use in a moderate drinking community sample.	Miller AP et al.	—	2019	→
Polygenic risk for alcohol misuse is moderated by romantic partnerships.	Barr PB et al.	—	2019	→
Polygenic risk scoring and prediction of mental health outcomes.	Anderson JS et al.	—	2019	→
Predictive modeling of schizophrenia from genomic data: Comparison of polygenic risk score with kernel support vector machines approach.	Vivian-Griffiths T et al.	—	2019	→
Progress in iPSC-Based Modeling of Psychiatric Disorders.	Hoffmann A et al.	—	2019	→
Psychiatric genetics researchers' views on offering return of results to individual participants.	Kostick KM et al.	—	2019	→
Recent advances of induced pluripotent stem cells application in neurodegenerative diseases.	Amin N et al.	—	2019	→
Re-examining physician-scientist training through the prism of the discovery-invention cycle.	Sarma GP et al.	—	2019	→
Right care, first time: a highly personalised and measurement-based care model to manage youth mental health.	Hickie IB et al.	—	2019	→
Schizophrenia risk factors in exceptional achievers: a re-analysis of a 60-year-old database.	Szöke A et al.	—	2019	→
Serotonergic multilocus genetic variation moderates the association between major interpersonal stress and adolescent depressive symptoms: Replication and candidate environment specification.	Starr LR et al.	—	2019	→
Shared Genetic Risk of Schizophrenia and Gray Matter Reduction in 6p22.1.	Chen J et al.	—	2019	→
Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior.	Gokhale A et al.	—	2019	→
Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis.	Rees E et al.	—	2019	→
Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene.	Bodkin JA et al.	—	2019	→
The schizophrenia and bipolar twin study in Sweden (STAR).	Johansson V et al.	—	2019	→
The Translational Potential of Neuroimaging Genomic Analyses To Diagnosis And Treatment In The Mental Disorders.	Chen J et al.	—	2019	→
The UKB envirome of depression: from interactions to synergistic effects.	Hullam G et al.	—	2019	→
Uncovering the Genetic Architecture of Major Depression.	McIntosh AM et al.	—	2019	→
Whole Exome Sequencing Identifies a Novel Predisposing Gene, MAPKAP1, for Familial Mixed Mood Disorder.	Yang C et al.	—	2019	→
A data-driven investigation of relationships between bipolar psychotic symptoms and schizophrenia genome-wide significant genetic loci.	Leonenko G et al.	—	2018	→
A Developmental Study of Abnormal Behaviors and Altered GABAergic Signaling in the VPA-Treated Rat Model of Autism.	Hou Q et al.	—	2018	→
A Genomically Informed Education System? Challenges for Behavioral Genetics.	Sabatello M	—	2018	→
Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.	Reinbold CS et al.	—	2018	→
A New <i>T. gondii</i> Mouse Model of Gene-Environment Interaction Relevant to Psychiatric Disease.	Kannan G et al.	—	2018	→
An Ontology Systems Approach on Human Brain Expression and Metaproteomics.	Flores Saiffe Farías A et al.	—	2018	→
A Schizophrenia-Linked KALRN Coding Variant Alters Neuron Morphology, Protein Function, and Transcript Stability.	Russell TA et al.	—	2018	→
ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties.	St Pourcain B et al.	—	2018	→
Assessing the evidence for shared genetic risks across psychiatric disorders and traits.	Martin J et al.	—	2018	→
Association between genetic variability of neuronal nitric oxide synthase and sensorimotor gating in humans.	Rovný R et al.	—	2018	→
Association of copy number variation across the genome with neuropsychiatric traits in the general population.	Guyatt AL et al.	—	2018	→
Associations between polygenic risk scores for four psychiatric illnesses and brain structure using multivariate pattern recognition.	Ranlund S et al.	—	2018	→
Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains.	Blakey R et al.	—	2018	→
A tutorial on conducting genome-wide association studies: Quality control and statistical analysis.	Marees AT et al.	—	2018	→
Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum.	LaBianca S et al.	—	2018	→
Building Models of Brain Disorders with Three-Dimensional Organoids.	Amin ND et al.	—	2018	→
Causal Inference on Pathophysiological Mediators in Psychiatry.	Namkung H et al.	—	2018	→
Childhood-Onset Schizophrenia: Insights from Induced Pluripotent Stem Cells.	Hoffmann A et al.	—	2018	→
Clinical associations of maternal thyroid function with foetal brain development: Epidemiological interpretation and overview of available evidence.	Korevaar TIM et al.	—	2018	→
Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model.	Wray NR et al.	—	2018	→
Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder.	Li X et al.	—	2018	→
Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.	Yang CP et al.	—	2018	→
Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network.	Jia P et al.	—	2018	→
Dendritic structural plasticity and neuropsychiatric disease.	Forrest MP et al.	—	2018	→
Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics.	Breuer R et al.	—	2018	→
DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders.	Jouroukhin Y et al.	—	2018	→
Discovery biology of neuropsychiatric syndromes (DBNS): a center for integrating clinical medicine and basic science.	Viswanath B et al.	—	2018	→
DNA methylation and clinical response to antidepressant medication in major depressive disorder: A review and recommendations.	Lisoway AJ et al.	—	2018	→
DNA sequence-level analyses reveal potential phenotypic modifiers in a large family with psychiatric disorders.	Ryan NM et al.	—	2018	→
Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.	Peyrot WJ et al.	—	2018	→
Dynamic Changes of the Mitochondria in Psychiatric Illnesses: New Mechanistic Insights From Human Neuronal Models.	Srivastava R et al.	—	2018	→
Embracing polygenicity: a review of methods and tools for psychiatric genetics research.	Maier RM et al.	—	2018	→
Environmental and Dietary Exposure to Copper and Its Cellular Mechanisms Linking to Alzheimer's Disease.	Hsu HW et al.	—	2018	→
Epigenetics, nutrition and mental health. Is there a relationship?	Stevens AJ et al.	—	2018	→
Further evidence for the genetic association between <i>CACNA1I</i> and schizophrenia.	Xie Y et al.	—	2018	→
Genetic and Epigenetic Alterations Underlie Oligodendroglia Susceptibility and White Matter Etiology in Psychiatric Disorders.	Chen X et al.	—	2018	→
Genetic identification of brain cell types underlying schizophrenia.	Skene NG et al.	—	2018	→
Genetic influences on prefrontal activation during a verbal fluency task in children: A twin study using near-infrared spectroscopy.	Sakakibara E et al.	—	2018	→
Genetics of Alzheimer's Disease.	Kim JH	—	2018	→
Genetic susceptibility in obsessive-compulsive disorder.	Fernandez TV et al.	—	2018	→
Genetic Variants Within Molecular Targets of Antipsychotic Treatment: Effects on Treatment Response, Schizophrenia Risk, and Psychopathological Features.	Calabrò M et al.	—	2018	→
Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register.	Hilker R et al.	—	2018	→
Hot Genes in Schizophrenia: How Clinical Datasets Could Help to Refine their Role.	Porcelli S et al.	—	2018	→
iMEGES: integrated mental-disorder GEnome score by deep neural network for prioritizing the susceptibility genes for mental disorders in personal genomes.	Khan A et al.	—	2018	→
Improved ethical guidance for the return of results from psychiatric genomics research.	Lázaro-Muñoz G et al.	—	2018	→
Increased BDNF methylation in saliva, but not blood, of patients with borderline personality disorder.	Thomas M et al.	—	2018	→
Integrating eQTL data with GWAS summary statistics in pathway-based analysis with application to schizophrenia.	Wu C et al.	—	2018	→
Integration of Enhancer-Promoter Interactions with GWAS Summary Results Identifies Novel Schizophrenia-Associated Genes and Pathways.	Wu C et al.	—	2018	→
<i>VRK2</i>, a Candidate Gene for Psychiatric and Neurological Disorders.	Li M et al.	—	2018	→
Low-frequency and rare variants may contribute to elucidate the genetics of major depressive disorder.	Yu C et al.	—	2018	→
Male increase in brain gene expression variability is linked to genetic risk for schizophrenia.	Chen J et al.	—	2018	→
microRNAs Sculpt Neuronal Communication in a Tight Balance That Is Lost in Neurological Disease.	Thomas KT et al.	—	2018	→
Multiplicative Effects of Social and Psychological Risk Factors on College Students' Suicidal Behaviors.	Assari S	—	2018	→
Neurogenetic Approaches to Stress and Fear in Humans as Pathophysiological Mechanisms for Posttraumatic Stress Disorder.	Nees F et al.	—	2018	→
Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes.	Herborg F et al.	—	2018	→
Organoids required! A new path to understanding human brain development and disease.	Arlotta P	—	2018	→
P2X7 Receptor: A Potential Therapeutic Target for Depression?	Deussing JM et al.	—	2018	→
[Pathophysiological implication of the VPAC2 receptor in psychiatric disorders].	Ago Y et al.	—	2018	→
Polygenic differential susceptibility to cumulative stress exposure and childhood obesity.	Sun Y et al.	—	2018	→
Polygenic Risk Score Prediction of Alcohol Dependence Symptoms Across Population-Based and Clinically Ascertained Samples.	Savage JE et al.	—	2018	→
Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population.	Jansen PR et al.	—	2018	→
Positive and balancing selection on <i>SLC18A1</i> gene associated with psychiatric disorders and human-unique personality traits.	Sato DX et al.	—	2018	→
Precision pharmacotherapy: psychiatry's future direction in preventing, diagnosing, and treating mental disorders.	Menke A	—	2018	→
Proximity labeling: spatially resolved proteomic mapping for neurobiology.	Han S et al.	—	2018	→
Psychosis as an Evolutionary Adaptive Mechanism to Changing Environments.	Scheepers FE et al.	—	2018	→
Psychotic Disorders.	Lieberman JA et al.	—	2018	→
Recent developments in the genetics of attention-deficit hyperactivity disorder.	Grimm O et al.	—	2018	→
Synaptic proteomics as a means to identify the molecular basis of mental illness: Are we getting there?	Reig-Viader R et al.	—	2018	→
The Andalusian Bipolar Family (ABiF) Study: Protocol and sample description.	Guzman-Parra J et al.	—	2018	→
The Candidate Schizophrenia Risk Gene DGCR2 Regulates Early Steps of Corticogenesis.	Molinard-Chenu A et al.	—	2018	→
The daunting polygenicity of mental illness: making a new map.	Hyman SE	—	2018	→
The emerging risk of exposure to air pollution on cognitive decline and Alzheimer's disease - Evidence from epidemiological and animal studies.	Kilian J et al.	—	2018	→
The functional variant rs334558 of <i>GSK3B</i> is associated with remission in patients with depressive disorders.	Levchenko A et al.	—	2018	→
The impact of epigenomic next-generation sequencing approaches on our understanding of neuropsychiatric disorders.	Schang AL et al.	—	2018	→
The integrated landscape of causal genes and pathways in schizophrenia.	Ma C et al.	—	2018	→
The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders.	Pedersen CB et al.	—	2018	→
The Lancet Commission on global mental health and sustainable development.	Patel V et al.	—	2018	→
The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders.	Amorim IS et al.	—	2018	→
Towards personalised positive psychiatry? : Commentary on "Vantage sensitivity: a framework for individual differences in response to psychological intervention".	Klingenberg B et al.	—	2018	→
Tracing Early Neurodevelopment in Schizophrenia with Induced Pluripotent Stem Cells.	Ahmad R et al.	—	2018	→
Trait and state biomarkers for psychiatric disorders: Importance of infrastructure to bridge the gap between basic and clinical research and industry.	Lema YY et al.	—	2018	→
Translational Significance of Selective Estrogen Receptor Modulators in Psychiatric Disorders.	Khan MM	—	2018	→
Unperturbed expression bias of imprinted genes in schizophrenia.	Gulyás-Kovács A et al.	—	2018	→
Why does the magnitude of genotype-by-environment interaction vary?	Saltz JB et al.	—	2018	→
A balanced translocation disrupting BCL2L10 and PNLDC1 segregates with affective psychosis.	Bouwkamp CG et al.	—	2017	→
A Gene-Based Analysis of Acoustic Startle Latency.	Smith AK et al.	—	2017	→
A Genome-Wide Association Study and Complex Network Identify Four Core Hub Genes in Bipolar Disorder.	Xie Z et al.	—	2017	→
A latent genetic subtype of major depression identified by whole-exome genotyping data in a Mexican-American cohort.	Yu C et al.	—	2017	→
Alcohol Misuse Across the Lifespan: Insights from Developmental Studies in Behavior Genetics.	Savage JE et al.	—	2017	→
A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score.	Ciuculete DM et al.	—	2017	→
Analysis of shared homozygosity regions in Saudi siblings with attention deficit hyperactivity disorder.	Shinwari JMA et al.	—	2017	→
A New Hope for Biological Insights Into Depression.	Hyman SE	—	2017	→
A novel strategy for clustering major depression individuals using whole-genome sequencing variant data.	Yu C et al.	—	2017	→
A Polygenic Risk Score of glutamatergic SNPs associated with schizophrenia predicts attentional behavior and related brain activity in healthy humans.	Rampino A et al.	—	2017	→
A review of molecular genetic studies of neurocognitive deficits in schizophrenia.	Zai G et al.	—	2017	→
Association of Alzhemier's disease with hepatitis C among patients with bipolar disorder.	Lin HC et al.	—	2017	→
Association of NKAPL, TSPAN18, and MPC2 gene variants with schizophrenia based on new data and a meta-analysis in Han Chinese.	Li Z et al.	—	2017	→
Autism risk following antidepressant medication during pregnancy.	Viktorin A et al.	—	2017	→
A Valuable New Direction in Ethical Analysis of Psychiatric Genetics.	Hyman SE	—	2017	→
Biometric Modeling of Gene-Environment Interplay: The Intersection of Theory and Method and Applications for Social Inequality.	South SC et al.	—	2017	→
Cdh13 and AdipoQ gene knockout alter instrumental and Pavlovian drug conditioning.	King CP et al.	—	2017	→
Child sexual abuse and the development of psychiatric disorders: a neurobiological trajectory of pathogenesis.	Shrivastava AK et al.	—	2017	→
Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms.	Schmitt A et al.	—	2017	→
Copy Number Variation in Syndromic Forms of Psychiatric Illness: The Emerging Value of Clinical Genetic Testing in Psychiatry.	Bouwkamp CG et al.	—	2017	→
DeepBipolar: Identifying genomic mutations for bipolar disorder via deep learning.	Sundaram L et al.	—	2017	→
Diagnostic and therapeutic potential of microRNAs in neuropsychiatric disorders: Past, present, and future.	Alural B et al.	—	2017	→
DISC1 in Astrocytes Influences Adult Neurogenesis and Hippocampus-Dependent Behaviors in Mice.	Terrillion CE et al.	—	2017	→
Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways.	Shao L et al.	—	2017	→
Does reflective functioning mediate the relationship between attachment and personality?	Nazzaro MP et al.	—	2017	→
Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics.	Hirayama-Kurogi M et al.	—	2017	→
Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility.	Sacchi S et al.	—	2017	→
Emerging roles for ncRNAs in alcohol use disorders.	Mayfield RD	—	2017	→
Environmental factors, life events, and trauma in the course of bipolar disorder.	Aldinger F et al.	—	2017	→
Epigenomics of Major Depressive Disorders and Schizophrenia: Early Life Decides.	Hoffmann A et al.	—	2017	→
Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 × DISC1.	O'Tuathaigh CM et al.	—	2017	→
Evolving Notions of Schizophrenia as a Developmental Neurocognitive Disorder.	Seidman LJ et al.	—	2017	→
Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa.	Yilmaz Z et al.	—	2017	→
Fine-mapping of antipsychotic response genome-wide association studies reveals novel regulatory mechanisms.	Ovenden ES et al.	—	2017	→
Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity.	Kim MJ et al.	—	2017	→
Further evidence for genetic variation at the serotonin transporter gene SLC6A4 contributing toward anxiety.	Forstner AJ et al.	—	2017	→
Gene-set analysis shows association between FMRP targets and autism spectrum disorder.	Jansen A et al.	—	2017	→
Genetic and molecular risk factors within the newly identified primate-specific exon of the SAP97/DLG1 gene in the 3q29 schizophrenia-associated locus.	Uezato A et al.	—	2017	→
Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus.	Schulz H et al.	—	2017	→
Genomic Contraindications for Heart Transplantation.	Char DS et al.	—	2017	→
High-resolution copy number variation analysis of schizophrenia in Japan.	Kushima I et al.	—	2017	→
Hippocampal-prefrontal connectivity as a translational phenotype for schizophrenia.	Bähner F et al.	—	2017	→
History of Bipolar Disorder and the Risk of Dementia: A Systematic Review and Meta-Analysis.	Diniz BS et al.	—	2017	→
How Wnt Signaling Builds the Brain: Bridging Development and Disease.	Noelanders R et al.	—	2017	→
Identification of shared risk loci and pathways for bipolar disorder and schizophrenia.	Forstner AJ et al.	—	2017	→
Identifying genes for neurobehavioural traits in rodents: progress and pitfalls.	Baud A et al.	—	2017	→
Influence of Familial Risk for Depression on Cortico-Limbic Connectivity During Implicit Emotional Processing.	Wackerhagen C et al.	—	2017	→
Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder.	Noh HJ et al.	—	2017	→
Intergenerational Transmission of Maternal Childhood Maltreatment Exposure: Implications for Fetal Brain Development.	Buss C et al.	—	2017	→
Investigation of copy number variation in subjects with major depression based on whole-genome sequencing data.	Yu C et al.	—	2017	→
Investigation of SHANK3 in schizophrenia.	de Sena Cortabitarte A et al.	—	2017	→
Lack of replication of previous autism spectrum disorder GWAS hits in European populations.	Torrico B et al.	—	2017	→
Mapping 22q11.2 Gene Dosage Effects on Brain Morphometry.	Lin A et al.	—	2017	→
Mice lacking the chromodomain helicase DNA-binding 5 chromatin remodeler display autism-like characteristics.	Pisansky MT et al.	—	2017	→
Modeling neurodevelopmental and psychiatric diseases with human iPSCs.	Wen Z	—	2017	→
Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain.	Barbash S et al.	—	2017	→
No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes.	Johnson EC et al.	—	2017	→
Omics analysis of mouse brain models of human diseases.	Paban V et al.	—	2017	→
Parenting and adolescents' psychological adjustment: Longitudinal moderation by adolescents' genetic sensitivity.	Stocker CM et al.	—	2017	→
Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse.	Feldcamp LA et al.	—	2017	→
Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring.	Fernández de Cossío L et al.	—	2017	→
Prenatal maternal immune activation and brain development with relevance to psychiatric disorders.	Scola G et al.	—	2017	→
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.	Tobe BTD et al.	—	2017	→
Progress in Genetic Studies of Tourette's Syndrome.	Qi Y et al.	—	2017	→
Rare genetic variants in CX3CR1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders.	Ishizuka K et al.	—	2017	→
Reproductive fitness and genetic risk of psychiatric disorders in the general population.	Mullins N et al.	—	2017	→
Review: Genetic research on alcohol use outcomes in African American populations: A review of the literature, associated challenges, and implications.	Dick DM et al.	—	2017	→
Role of calcium channels in bipolar disorder.	D'Onofrio S et al.	—	2017	→
Schizophrenia and the dynamic genome.	Sullivan PF	—	2017	→
Schizophrenia and the neurodevelopmental continuum:evidence from genomics.	Owen MJ et al.	—	2017	→
Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.	Duncan L et al.	—	2017	→
Social inequality, scientific inequality, and the future of mental illness.	Dean CE	—	2017	→
Strength of functional signature correlates with effect size in autism.	Ballouz S et al.	—	2017	→
SZDB: A Database for Schizophrenia Genetic Research.	Wu Y et al.	—	2017	→
SZGR 2.0: a one-stop shop of schizophrenia candidate genes.	Jia P et al.	—	2017	→
Text mining and expert curation to develop a database on psychiatric diseases and their genes.	Gutiérrez-Sacristán A et al.	—	2017	→
The coexistence of psychiatric and gastrointestinal problems in children with restrictive eating in a nationwide Swedish twin study.	Täljemark J et al.	—	2017	→
The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening.	Gonzalez DM et al.	—	2017	→
The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology.	Namkung H et al.	—	2017	→
The PHF21B gene is associated with major depression and modulates the stress response.	Wong ML et al.	—	2017	→
Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders.	Rutkowski TP et al.	—	2017	→
Variant effect prediction tools assessed using independent, functional assay-based datasets: implications for discovery and diagnostics.	Mahmood K et al.	—	2017	→
Whole-exome sequencing of individuals from an isolated population implicates rare risk variants in bipolar disorder.	Lescai F et al.	—	2017	→
Whole exome sequencing reveals inherited and de novo variants in autism spectrum disorder: a trio study from Saudi families.	Al-Mubarak B et al.	—	2017	→
Whole-genome sequencing of monozygotic twins discordant for schizophrenia indicates multiple genetic risk factors for schizophrenia.	Tang J et al.	—	2017	→
Whole-genome single nucleotide variant distribution on genomic regions and its relationship to major depression.	Yu C et al.	—	2017	→
A Danish Twin Study of Schizophrenia Liability: Investigation from Interviewed Twins for Genetic Links to Affective Psychoses and for Cross-Cohort Comparisons.	Kläning U et al.	—	2016	→
Advancing drug discovery for neuropsychiatric disorders using patient-specific stem cell models.	Haggarty SJ et al.	—	2016	→
A genome-wide screen for acrophobia susceptibility loci in a Finnish isolate.	Misiewicz Z et al.	—	2016	→
Analysis of Intellectual Disability Copy Number Variants for Association With Schizophrenia.	Rees E et al.	—	2016	→
Animal models of gene-environment interaction in schizophrenia: A dimensional perspective.	Ayhan Y et al.	—	2016	→
A novel 3q29 deletion associated with autism, intellectual disability, psychiatric disorders, and obesity.	Biamino E et al.	—	2016	→
A pilot randomized clinical trial evaluating the impact of genetic counseling for serious mental illnesses.	Hippman C et al.	—	2016	→
A pilot study on commonality and specificity of copy number variants in schizophrenia and bipolar disorder.	Chen J et al.	—	2016	→
Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study.	Montano C et al.	—	2016	→
Association of PDE4B Polymorphisms with Susceptibility to Schizophrenia: A Meta-Analysis of Case-Control Studies.	Feng Y et al.	—	2016	→
Associations between a locus downstream DRD1 gene and cerebrospinal fluid dopamine metabolite concentrations in psychosis.	Andreou D et al.	—	2016	→
Back to basics: luring industry back into neuroscience.	Hyman SE	—	2016	→
Brain change trajectories that differentiate the major psychoses.	Liberg B et al.	—	2016	→
Caution When Diagnosing Your Mouse With Schizophrenia: The Use and Misuse of Model Animals for Understanding Psychiatric Disorders.	Wong AH et al.	—	2016	→
Cell Type-Specific Effects of Mutant DISC1: A Proteomics Study.	Xia M et al.	—	2016	→
Clinical and neuroimaging characterization of two C9orf72-positive siblings with amyotrophic lateral sclerosis and schizophrenia.	Vázquez-Costa JF et al.	—	2016	→
Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis.	Rao S et al.	—	2016	→
Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.	Yang J et al.	—	2016	→
Cross-Disorder Psychiatric Genomics.	Docherty AR et al.	—	2016	→
Detection of gene-environment interaction in pedigree data using genome-wide genotypes.	Nivard MG et al.	—	2016	→
Disease and Polygenic Architecture: Avoid Trio Design and Appropriately Account for Unscreened Control Subjects for Common Disease.	Peyrot WJ et al.	—	2016	→
Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro.	Tropea D et al.	—	2016	→
Electrophysiological Endophenotypes for Schizophrenia.	Owens EM et al.	—	2016	→
Evaluation of voltage-dependent calcium channel γ gene families identified several novel potential susceptible genes to schizophrenia.	Guan F et al.	—	2016	→
Exome arrays capture polygenic rare variant contributions to schizophrenia.	Richards AL et al.	—	2016	→
Exome Sequencing of Familial Bipolar Disorder.	Goes FS et al.	—	2016	→
Expanding the phenotype of Triple X syndrome: A comparison of prenatal versus postnatal diagnosis.	Wigby K et al.	—	2016	→
From Linkage Studies to Epigenetics: What We Know and What We Need to Know in the Neurobiology of Schizophrenia.	Cariaga-Martinez A et al.	—	2016	→
Functional connectivity measures as schizophrenia intermediate phenotypes: advances, limitations, and future directions.	Cao H et al.	—	2016	→
Further evidence for deletions in 7p14.1 contributing to nonsyndromic cleft lip with or without cleft palate.	Klamt J et al.	—	2016	→
G72 primate-specific gene: a still enigmatic element in psychiatric disorders.	Sacchi S et al.	—	2016	→
Gender differences in CNV burden do not confound schizophrenia CNV associations.	Han J et al.	—	2016	→
Genes Involved in Neurodevelopment, Neuroplasticity, and Bipolar Disorder: CACNA1C, CHRNA1, and MAPK1.	Calabrò M et al.	—	2016	→
Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database.	Li J et al.	—	2016	→
Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis.	McIntosh AM et al.	—	2016	→
Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions.	Mirkovic B et al.	—	2016	→
Genetic imaging consortium for addiction medicine: From neuroimaging to genes.	Mackey S et al.	—	2016	→
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.	Franke B et al.	—	2016	→
Genetic influences on the neural and physiological bases of acute threat: A research domain criteria (RDoC) perspective.	Sumner JA et al.	—	2016	→
Genome Engineering with TALE and CRISPR Systems in Neuroscience.	Lee HB et al.	—	2016	→
Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.	Stringer S et al.	—	2016	→
Heritability of Perinatal Depression and Genetic Overlap With Nonperinatal Depression.	Viktorin A et al.	—	2016	→
Identification of rare variants in KCTD13 at the schizophrenia risk locus 16p11.2.	Degenhardt F et al.	—	2016	→
Identification of SLC25A37 as a major depressive disorder risk gene.	Huo YX et al.	—	2016	→
Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis.	de Jong S et al.	—	2016	→
In search of predictive endophenotypes in addiction: insights from preclinical research.	Belin D et al.	—	2016	→
Investigation of Rare Single-Nucleotide PCDH15 Variants in Schizophrenia and Autism Spectrum Disorders.	Ishizuka K et al.	—	2016	→
Investigation of single-nucleotide variants in MBD5 associated with autism spectrum disorders and schizophrenia phenotypes.	Ishizuka K et al.	—	2016	→
Modeling psychiatric disorders: from genomic findings to cellular phenotypes.	Falk A et al.	—	2016	→
Modeling psychiatric disorders with patient-derived iPSCs.	Wen Z et al.	—	2016	→
Models of Intergenerational and Transgenerational Transmission of Risk for Psychopathology in Mice.	Klengel T et al.	—	2016	→
Molecular genetic approaches to understanding the comorbidity of psychiatric disorders.	Gizer IR	—	2016	→
Molecular substrates of schizophrenia: homeostatic signaling to connectivity.	Landek-Salgado MA et al.	—	2016	→
Multidimensional heritability analysis of neuroanatomical shape.	Ge T et al.	—	2016	→
Myelination-related genes are associated with decreased white matter integrity in schizophrenia.	Chavarria-Siles I et al.	—	2016	→
On being a circuit psychiatrist.	Gordon JA	—	2016	→
Overactive bladder in children.	Franco I	—	2016	→
Preliminary assessment of pre-morbid DNA methylation in individuals at high genetic risk of mood disorders.	Walker RM et al.	—	2016	→
Profiling depression in childhood and adolescence: the role of conduct problems.	Riglin L et al.	—	2016	→
Protein Interaction Networks Link Schizophrenia Risk Loci to Synaptic Function.	Schwarz E et al.	—	2016	→
Proteomics Research in Schizophrenia.	Davalieva K et al.	—	2016	→
Quantitative Trait Loci and a Novel Genetic Candidate for Fear Learning.	Knoll AT et al.	—	2016	→
Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans.	Li M et al.	—	2016	→
Replication analyses of four chromosomal deletions with schizophrenia via independent large-scale meta-analyses.	Chang H et al.	—	2016	→
Resequencing and Association Analysis of Six PSD-95-Related Genes as Possible Susceptibility Genes for Schizophrenia and Autism Spectrum Disorders.	Xing J et al.	—	2016	→
Role of epigenetic factors in the development of mental illness throughout life.	Guintivano J et al.	—	2016	→
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the management of schizophrenia and related disorders.	Galletly C et al.	—	2016	→
Schizophrenia.	Owen MJ et al.	—	2016	→
The continuum of causality in human genetic disorders.	Katsanis N	—	2016	→
The Future is The Past: Methylation QTLs in Schizophrenia.	Hoffmann A et al.	—	2016	→
The Influence of Trauma, Life Events, and Social Relationships on Bipolar Depression.	Johnson SL et al.	—	2016	→
The inverse link between genetic risk for schizophrenia and migraine through NMDA (N-methyl-D-aspartate) receptor activation via D-serine.	Van der Auwera S et al.	—	2016	→
The microtubule-associated molecular pathways may be genetically disrupted in patients with Bipolar Disorder. Insights from the molecular cascades.	Drago A et al.	—	2016	→
Theory of mind network activity is altered in subjects with familial liability for schizophrenia.	Mohnke S et al.	—	2016	→
The promises and challenges of human brain organoids as models of neuropsychiatric disease.	Quadrato G et al.	—	2016	→
The road to precision psychiatry: translating genetics into disease mechanisms.	Gandal MJ et al.	—	2016	→
The statistical properties of gene-set analysis.	de Leeuw CA et al.	—	2016	→
Translating Neurogenomics Into New Medicines.	Wendland JR et al.	—	2016	→
Type 3 adenylyl cyclase: a key enzyme mediating the cAMP signaling in neuronal cilia.	Qiu L et al.	—	2016	→
Using model systems to understand errant plasticity mechanisms in psychiatric disorders.	Averbeck BB et al.	—	2016	→
Addressing the Genetics of Human Mental Health Disorders in Model Organisms.	McCammon JM et al.	—	2015	→
Advancing parental age and autism: multifactorial pathways.	Lee BK et al.	—	2015	→
Aetiological stratification as a conceptual framework for gene-by-environment interaction research in psychiatry.	van Winkel R	—	2015	→
A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis.	Higgins GA et al.	—	2015	→
A kernel machine method for detecting effects of interaction between multidimensional variable sets: an imaging genetics application.	Ge T et al.	—	2015	→
Allele-specific copy-number discovery from whole-genome and whole-exome sequencing.	Wang W et al.	—	2015	→
Alterations in neural Theory of Mind processing in euthymic patients with bipolar disorder and unaffected relatives.	Willert A et al.	—	2015	→
Analysis of conditional heterozygous STXBP1 mutations in human neurons.	Patzke C et al.	—	2015	→
A New Method for Detecting Associations with Rare Copy-Number Variants.	Tzeng JY et al.	—	2015	→
Anorexia nervosa.	Treasure J et al.	—	2015	→
A significant risk locus on 19q13 for bipolar disorder identified using a combined genome-wide linkage and copy number variation analysis.	Lekman M et al.	—	2015	→
Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals.	Fullerton JM et al.	—	2015	→
Associating schizophrenia, long non-coding RNAs and neurostructural dynamics.	Merelo V et al.	—	2015	→
Association analysis of the Cadherin13 gene with schizophrenia in the Japanese population.	Otsuka I et al.	—	2015	→
Association of age-of-onset groups with GWAS significant schizophrenia and bipolar disorder loci in Romanian bipolar I patients.	Grigoroiu-Serbanescu M et al.	—	2015	→
Association of TCF4 polymorphisms and Fuchs' endothelial dystrophy: a meta-analysis.	Li D et al.	—	2015	→
Autism: Oxytocin, serotonin, and social reward.	Dölen G	—	2015	→
Biomarkers for Psychiatry: The Journey from Fantasy to Fact, a Report of the 2013 CINP Think Tank.	Scarr E et al.	—	2015	→
Bipolar disorder and its relation to major psychiatric disorders: a family-based study in the Swedish population.	Song J et al.	—	2015	→
Candidate gene-environment interaction research: reflections and recommendations.	Dick DM et al.	—	2015	→
CHALLENGES FOR IMPLEMENTING A PTSD PREVENTIVE GENOMIC SEQUENCING PROGRAM IN THE U.S. MILITARY.	Lázaro-Muñoz G et al.	—	2015	→
Circadian Clock Dysfunction and Psychiatric Disease: Could Fruit Flies have a Say?	Zordan MA et al.	—	2015	→
Cognitive impairments are different in single-incidence and multi-incidence ADHD families.	Oerlemans AM et al.	—	2015	→
Common variants in the ARC gene are not associated with cognitive abilities.	Myrum C et al.	—	2015	→
Convergence of advances in genomics, team science, and repositories as drivers of progress in psychiatric genomics.	Lehner T et al.	—	2015	→
Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder.	Kember RL et al.	—	2015	→
CRY1 Variations Impacts on the Depressive Relapse Rate in a Sample of Bipolar Patients.	Drago A et al.	—	2015	→
Decoding Advances in Psychiatric Genetics: A Focus on Neural Circuits in Rodent Models.	Heckenast JR et al.	—	2015	→
Detection and treatment of at-risk mental state for developing a first psychosis: making up the balance.	Nieman DH et al.	—	2015	→
Dopamine in socioecological and evolutionary perspectives: implications for psychiatric disorders.	Yamaguchi Y et al.	—	2015	→
Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior.	Genestine M et al.	—	2015	→
Epigenomic mapping and effect sizes of noncoding variants associated with psychotropic drug response.	Higgins GA et al.	—	2015	→
Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain.	Mo A et al.	—	2015	→
Evaluating historical candidate genes for schizophrenia.	Farrell MS et al.	—	2015	→
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci.	Andreassen OA et al.	—	2015	→
Genetic research in autism spectrum disorders.	Robinson EB et al.	—	2015	→
Genetic risk for schizophrenia: convergence on synaptic pathways involved in plasticity.	Hall J et al.	—	2015	→
Genetics and brain morphology.	Strike LT et al.	—	2015	→
Genetics and Epigenetics of Eating Disorders.	Yilmaz Z et al.	—	2015	→
Genetic studies of schizophrenia: an update.	Chen J et al.	—	2015	→
Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder.	Forstner AJ et al.	—	2015	→
Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.	Luykx JJ et al.	—	2015	→
Genome-wide association study of schizophrenia in Ashkenazi Jews.	Goes FS et al.	—	2015	→
Genome-wide burden of deleterious coding variants increased in schizophrenia.	Loohuis LMO et al.	—	2015	→
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.	Srikanth P et al.	—	2015	→
Identification and functional characterization of rare SHANK2 variants in schizophrenia.	Peykov S et al.	—	2015	→
Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility.	Kimura H et al.	—	2015	→
Identification of schizophrenia-associated loci by combining DNA methylation and gene expression data from whole blood.	van Eijk KR et al.	—	2015	→
Investigation of the role of TCF4 rare sequence variants in schizophrenia.	Basmanav FB et al.	—	2015	→
Is serotonin an upper or a downer? The evolution of the serotonergic system and its role in depression and the antidepressant response.	Andrews PW et al.	—	2015	→
JAG: A Computational Tool to Evaluate the Role of Gene-Sets in Complex Traits.	Lips ES et al.	—	2015	→
Microendophenotypes of psychiatric disorders: phenotypes of psychiatric disorders at the level of molecular dynamics, synapses, neurons, and neural circuits.	Kida S et al.	—	2015	→
[Neurobiology of schizophrenia: new findings from the structure to the molecules].	Schmitt A et al.	—	2015	→
Neuronal migration abnormalities and its possible implications for schizophrenia.	Muraki K et al.	—	2015	→
New discoveries in schizophrenia genetics reveal neurobiological pathways: A review of recent findings.	Kotlar AV et al.	—	2015	→
Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia.	Pocklington AJ et al.	—	2015	→
Novel genetic advances in schizophrenia: an interview with Michael O'Donovan.	O'Donovan M	—	2015	→
Pharmacogenetics of alcohol use disorders and comorbid psychiatric disorders.	Helton SG et al.	—	2015	→
PhenoPredict: A disease phenome-wide drug repositioning approach towards schizophrenia drug discovery.	Xu R et al.	—	2015	→
Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis.	Musliner KL et al.	—	2015	→
Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders.	Choi SY et al.	—	2015	→
Psychiatrist attitudes towards pharmacogenetic testing, direct-to-consumer genetic testing, and integrating genetic counseling into psychiatric patient care.	Thompson C et al.	—	2015	→
PsyGeNET: a knowledge platform on psychiatric disorders and their genes.	Gutiérrez-Sacristán A et al.	—	2015	→
Recent genetic findings in schizophrenia and their therapeutic relevance.	Harrison PJ	—	2015	→
Refinement of schizophrenia GWAS loci using methylome-wide association data.	Kumar G et al.	—	2015	→
Risky Business: Pathways to Progress in Biologically Informed Studies of Psychopathology.	Agrawal A et al.	—	2015	→
Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models.	Samsom JN et al.	—	2015	→
Schizophrenia genetics: emerging themes for a complex disorder.	Kavanagh DH et al.	—	2015	→
Schizophrenia: Hope on the Horizon.	Sullivan PF	—	2015	→
Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD.	Stergiakouli E et al.	—	2015	→
Simplex and multiplex stratification in ASD and ADHD families: a promising approach for identifying overlapping and unique underpinnings of ASD and ADHD?	Oerlemans AM et al.	—	2015	→
Social responsiveness, an autism endophenotype: genomewide significant linkage to two regions on chromosome 8.	Lowe JK et al.	—	2015	→
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.	Johnson MR et al.	—	2015	→
The 5-HTTLPR confers susceptibility to anorexia nervosa in Han Chinese: evidence from a case-control and family-based study.	Chen J et al.	—	2015	→
The effect of ANK3 bipolar-risk polymorphisms on the working memory circuitry differs between loci and according to risk-status for bipolar disorder.	Delvecchio G et al.	—	2015	→
The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort.	Robinson EB et al.	—	2015	→
The pharmacogenetics of alcohol use disorder.	Jones JD et al.	—	2015	→
The Power of Theory, Research Design, and Transdisciplinary Integration in Moving Psychopathology Forward.	Vaidyanathan U et al.	—	2015	→
The promise of biomarkers in diagnosing major depression in primary care: the present and future.	Redei EE et al.	—	2015	→
The promise of psychiatric pharmacogenomics.	Hamilton SP	—	2015	→
The proteome of schizophrenia.	Nascimento JM et al.	—	2015	→
The PsychENCODE project.	PsychENCODE Consortium et al.	—	2015	→
The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.	Logue MW et al.	—	2015	→
The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods.	Dietrich A et al.	—	2015	→
Toward stratified treatments for bipolar disorders.	Hasler G et al.	—	2015	→
Understanding Language from a Genomic Perspective.	Graham SA et al.	—	2015	→
XRCC5 as a risk gene for alcohol dependence: evidence from a genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans.	Juraeva D et al.	—	2015	→
ZNF804A genetic variation (rs1344706) affects brain grey but not white matter in schizophrenia and healthy subjects.	Nenadic I et al.	—	2015	→
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.	Thomson PA et al.	—	2014	→
A common microdeletion affecting a hippocampus- and amygdala-specific isoform of tryptophan hydroxylase 2 is not associated with affective disorders.	Hammer C et al.	—	2014	→
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.	Psychosis Endophenotypes International Consortium et al.	—	2014	→
A genome-wide association study of anorexia nervosa.	Boraska V et al.	—	2014	→
A meta-analysis of gene expression quantitative trait loci in brain.	Kim Y et al.	—	2014	→
An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.	Morris DW et al.	—	2014	→
An overview of measuring impulsive behavior in mice.	Dent CL et al.	—	2014	→
Antidepressant treatment response is modulated by genetic and environmental factors and their interactions.	Kovacs D et al.	—	2014	→
A polygenic burden of rare disruptive mutations in schizophrenia.	Purcell SM et al.	—	2014	→
A population-based study of genetic variation and psychotic experiences in adolescents.	Zammit S et al.	—	2014	→
A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder.	Strauss KA et al.	—	2014	→
Applying polygenic risk scores to postpartum depression.	Byrne EM et al.	—	2014	→
Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age.	Zannas AS et al.	—	2014	→
A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing.	Hu X et al.	—	2014	→
Autism spectrum disorder severity reflects the average contribution of de novo and familial influences.	Robinson EB et al.	—	2014	→
Biological insights from 108 schizophrenia-associated genetic loci.	Schizophrenia Working Group of the Psychiatric Genomics Consortium	—	2014	→
Candidate gene associations with mood disorder, cognitive vulnerability, and fronto-limbic volumes.	Frazier TW et al.	—	2014	→
Carbonyl stress and schizophrenia.	Arai M et al.	—	2014	→
Changes in the adolescent brain and the pathophysiology of psychotic disorders.	Keshavan MS et al.	—	2014	→
Common DNA methylation alterations in multiple brain regions in autism.	Ladd-Acosta C et al.	—	2014	→
Comprehensive identification of single nucleotide polymorphisms associated with beta-lactam resistance within pneumococcal mosaic genes.	Chewapreecha C et al.	—	2014	→
Copy number variation in schizophrenia in Sweden.	Szatkiewicz JP et al.	—	2014	→
Cryptic and complex chromosomal aberrations in early-onset neuropsychiatric disorders.	Brand H et al.	—	2014	→
De novo mutations in schizophrenia implicate synaptic networks.	Fromer M et al.	—	2014	→
Drosophila melanogaster as a genetic model system to study neurotransmitter transporters.	Martin CA et al.	—	2014	→
DSM-5 cannabis use disorder: a phenotypic and genomic perspective.	Agrawal A et al.	—	2014	→
EGFR and FGFR pathways have distinct roles in Drosophila mushroom body development and ethanol-induced behavior.	King IF et al.	—	2014	→
Environmental stressors and epigenetic control of the hypothalamic-pituitary-adrenal axis.	Lee RS et al.	—	2014	→
Epigenetic analysis of neurocognitive development at 1 year of age in a community-based pregnancy cohort.	Krushkal J et al.	—	2014	→
Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data.	Chen GB et al.	—	2014	→
Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants.	Yang C et al.	—	2014	→
FamAnn: an automated variant annotation pipeline to facilitate target discovery for family-based sequencing studies.	Yao J et al.	—	2014	→
Gene-based rare allele analysis identified a risk gene of Alzheimer's disease.	Kim JH et al.	—	2014	→
Gene-environment interaction.	Manuck SB et al.	—	2014	→
Gene-environment interaction research in psychiatric epidemiology: a framework and implications for study design.	Belsky DW et al.	—	2014	→
Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism.	Zannas AS et al.	—	2014	→
[Genes « for » schizophrenia].	Jordan B	—	2014	→
Genetic and environmental influences on rumination and its covariation with depression.	Johnson DP et al.	—	2014	→
Genetic architecture of cognitive traits.	Le Hellard S et al.	—	2014	→
Genetic association analysis of 300 genes identifies a risk haplotype in SLC18A2 for post-traumatic stress disorder in two independent samples.	Solovieff N et al.	—	2014	→
Genetic association signal near NTN4 in Tourette syndrome.	Paschou P et al.	—	2014	→
Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder.	Cardno AG et al.	—	2014	→
Genetics in psychiatry.	Umesh S et al.	—	2014	→
Genetics of alcohol dependence: a review of clinical studies.	Samochowiec J et al.	—	2014	→
Genetics of cognition in epilepsy.	Busch RM et al.	—	2014	→
Genetics of obsessive-compulsive disorder and related disorders.	Browne HA et al.	—	2014	→
Genome-scale neurogenetics: methodology and meaning.	McCarroll SA et al.	—	2014	→
Genome-wide association study reveals two new risk loci for bipolar disorder.	Mühleisen TW et al.	—	2014	→
Genome-wide scans of genetic variants for psychophysiological endophenotypes: a methodological overview.	Iacono WG et al.	—	2014	→
Glutamate receptor mutations in psychiatric and neurodevelopmental disorders.	Soto D et al.	—	2014	→
Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.	van den Berg SM et al.	—	2014	→
Heritability and genomics of gene expression in peripheral blood.	Wright FA et al.	—	2014	→
Heritability and molecular genetic basis of antisaccade eye tracking error rate: a genome-wide association study.	Vaidyanathan U et al.	—	2014	→
Heritability and molecular genetic basis of electrodermal activity: a genome-wide association study.	Vaidyanathan U et al.	—	2014	→
High-resolution genetic mapping of complex traits from a combined analysis of F2 and advanced intercross mice.	Parker CC et al.	—	2014	→
How might ZNF804A variants influence risk for schizophrenia and bipolar disorder? A literature review, synthesis, and bioinformatic analysis.	Hess JL et al.	—	2014	→
Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia.	Jenkins A et al.	—	2014	→
Identification of gene ontologies linked to prefrontal-hippocampal functional coupling in the human brain.	Dixson L et al.	—	2014	→
Identifying Potential Regions of Copy Number Variation for Bipolar Disorder.	Chen YH et al.	—	2014	→
Integrating genetics and social science: genetic risk scores.	Belsky DW et al.	—	2014	→
Interplay between childhood physical abuse and familial risk in the onset of psychotic disorders.	Fisher HL et al.	—	2014	→
Mental disorders are somatic disorders, a comment on M. Stier and T. Schramme.	Rietschel M	—	2014	→
Mental health: depression needs large human-genetics studies.	Hyman S	—	2014	→
Mentalizing functions provide a conceptual link of brain function and social cognition in major mental disorders.	Schnell K	—	2014	→
Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults.	Aberg KA et al.	—	2014	→
Microglia modulate wiring of the embryonic forebrain.	Squarzoni P et al.	—	2014	→
Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant.	Folcher M et al.	—	2014	→
Mind the gap: why many geneticists and psychological scientists have discrepant views about gene-environment interaction (G×E) research.	Duncan LE et al.	—	2014	→
Missing heritability of common diseases and treatments outside the protein-coding exome.	Sadee W et al.	—	2014	→
Mitochondrial DNA (mtDNA) variants in the European haplogroups HV, JT, and U do not have a major role in schizophrenia.	Torrell H et al.	—	2014	→
Modelling the genetic contribution to mental illness: a timely end for the psychiatric rodent?	Davis BA et al.	—	2014	→
Molecular network analysis enhances understanding of the biology of mental disorders.	Grennan KS et al.	—	2014	→
Multiple sclerosis and psychiatric disorders: comorbidity and sibling risk in a nationwide Swedish cohort.	Johansson V et al.	—	2014	→
Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees.	Fears SC et al.	—	2014	→
Mutant disrupted-in-schizophrenia 1 in astrocytes: focus on glutamate metabolism.	Abazyan S et al.	—	2014	→
Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment.	Millan MJ et al.	—	2014	→
Neuropsychiatric genetics in developing countries: Current challenges.	Forero DA et al.	—	2014	→
New approaches to psychiatric diagnostic classification.	Owen MJ	—	2014	→
One gene, many neuropsychiatric disorders: lessons from Mendelian diseases.	Zhu X et al.	—	2014	→
Opposite risk patterns for autism and schizophrenia are associated with normal variation in birth size: phenotypic support for hypothesized diametric gene-dosage effects.	Byars SG et al.	—	2014	→
Pathway analyses implicate glial cells in schizophrenia.	Duncan LE et al.	—	2014	→
Patterns of variation influencing antipsychotic treatment outcomes in South African first-episode schizophrenia patients.	Drogemöller BI et al.	—	2014	→
PD_NGSAtlas: a reference database combining next-generation sequencing epigenomic and transcriptomic data for psychiatric disorders.	Zhao Z et al.	—	2014	→
Peripheral biomarkers revisited: integrative profiling of peripheral samples for psychiatric research.	Hayashi-Takagi A et al.	—	2014	→
Polymorphisms in genes implicated in dopamine, serotonin and noradrenalin metabolism suggest association with cerebrospinal fluid monoamine metabolite concentrations in psychosis.	Andreou D et al.	—	2014	→
Practitioner review: A critical perspective on gene-environment interaction models--what impact should they have on clinical perceptions and practice?	Munafò MR et al.	—	2014	→
Pre-clinical models of neurodevelopmental disorders: focus on the cerebellum.	Shevelkin AV et al.	—	2014	→
Psychiatrists' views of the genetic bases of mental disorders and behavioral traits and their use of genetic tests.	Klitzman R et al.	—	2014	→
Resequencing and association analysis of PTPRA, a possible susceptibility gene for schizophrenia and autism spectrum disorders.	Xing J et al.	—	2014	→
Resting EEG in psychosis and at-risk populations--a possible endophenotype?	Ranlund S et al.	—	2014	→
Revitalizing psychiatric therapeutics.	Hyman SE	—	2014	→
RNA-Seq reveals novel transcriptional reorganization in human alcoholic brain.	Farris SP et al.	—	2014	→
Single-cell, genome-wide sequencing identifies clonal somatic copy-number variation in the human brain.	Cai X et al.	—	2014	→
Synaptic dysregulation in a human iPS cell model of mental disorders.	Wen Z et al.	—	2014	→
The Amsterdam Sexual Abuse Case (ASAC)-study in day care centers: longitudinal effects of sexual abuse on infants and very young children and their parents, and the consequences of the persistence of abusive images on the internet.	Lindauer RJ et al.	—	2014	→
The effects of HPA axis function on cognition and its implications for the pathophysiology of bipolar disorder.	Young AH	—	2014	→
The emerging roles of TCF4 in disease and development.	Forrest MP et al.	—	2014	→
The Inheritance of Tourette Disorder: A review.	Pauls DL et al.	—	2014	→
The neurobiology of social environmental risk for schizophrenia: an evolving research field.	Akdeniz C et al.	—	2014	→
The theory of bipolar disorder as an illness of accelerated aging: implications for clinical care and research.	Rizzo LB et al.	—	2014	→
Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective.	Quednow BB et al.	—	2014	→
Translation: screening for novel therapeutics with disease-relevant cell types derived from human stem cell models.	Haggarty SJ et al.	—	2014	→
A comprehensive family-based replication study of schizophrenia genes.	Aberg KA et al.	—	2013	→
A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder.	Fernandes CP et al.	—	2013	→
Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.	Wallace TL et al.	—	2013	→
Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex.	Guella I et al.	—	2013	→
Antidepressant response and polygenes.	Purcell SM	—	2013	→
Association between autozygosity and major depression: stratification due to religious assortment.	Abdellaoui A et al.	—	2013	→
Biological pathways and genetic mechanisms involved in social functioning.	Ordoñana JR et al.	—	2013	→
Biomarkers for personalised treatment in psychiatric diseases.	Bagdy G et al.	—	2013	→
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and its implication in executive functions in adult offspring of alcohol-dependent probands.	Benzerouk F et al.	—	2013	→
Clinical classification in mental health at the cross-roads: which direction next?	Hickie IB et al.	—	2013	→
Comparison of gene expression profiles in the blood, hippocampus and prefrontal cortex of rats.	Witt SH et al.	—	2013	→
Comprehensive analysis of copy number variation in monozygotic twins discordant for bipolar disorder or schizophrenia.	Bloom RJ et al.	—	2013	→
Consideration of plausible genetic architectures for schizophrenia and implications for analytic approaches in the era of next generation sequencing.	Curtis D	—	2013	→
Copy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders.	Hiroi N et al.	—	2013	→
Copy number variation: what is it and what has it told us about child psychiatric disorders?	Thapar A et al.	—	2013	→
Detecting large copy number variants using exome genotyping arrays in a large Swedish schizophrenia sample.	Szatkiewicz JP et al.	—	2013	→
DISC1 genetics, biology and psychiatric illness.	Thomson PA et al.	—	2013	→
Does epilepsy in multiplex autism pedigrees define a different subgroup in terms of clinical characteristics and genetic risk?	Amiet C et al.	—	2013	→
Eating problems and overlap with ADHD and autism spectrum disorders in a nationwide twin study of 9- and 12-year-old children.	Råstam M et al.	—	2013	→
ENCODE and a new landscape for psychiatric genetics.	Nair A et al.	—	2013	→
Endophenotypes in psychopathology research: where do we stand?	Miller GA et al.	—	2013	→
Epidemiological and clinical characterization following a first psychotic episode in major depressive disorder: comparisons with schizophrenia and bipolar I disorder in the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS).	Owoeye O et al.	—	2013	→
Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes.	Del Pino I et al.	—	2013	→
Estrogen receptor 1 gene rs2295193 polymorphism and anorexia nervosa: new data and meta-analysis.	Zhang C et al.	—	2013	→
From candidate genes to genome-wide association: the challenges and promise of posttraumatic stress disorder genetic studies.	Koenen KC et al.	—	2013	→
Gene copy-number variation in haploid and diploid strains of the yeast Saccharomyces cerevisiae.	Zhang H et al.	—	2013	→
Gene expression profiles in relation to tension and dissociation in borderline personality disorder.	Schmahl C et al.	—	2013	→
General developmental health in the VPA-rat model of autism.	Favre MR et al.	—	2013	→
Genes and functional GI disorders: from casual to causal relationship.	D'Amato M	—	2013	→
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.	Cross-Disorder Group of the Psychiatric Genomics Consortium et al.	—	2013	→
Genetics of bipolar disorder.	Craddock N et al.	—	2013	→
Genetic variants associated with disordered eating.	Wade TD et al.	—	2013	→
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.	Ripke S et al.	—	2013	→
Genome-wide association studies in psychiatry: what have we learned?	Collins AL et al.	—	2013	→
Genome-wide association study of atypical psychosis.	Kanazawa T et al.	—	2013	→
Genomic and epigenomic insights into nutrition and brain disorders.	Dauncey MJ	—	2013	→
Global increases in both common and rare copy number load associated with autism.	Girirajan S et al.	—	2013	→
"He who sees things grow from the beginning will have the finest view of them" a systematic review of genetic studies on psychological traits in infancy.	Papageorgiou KA et al.	—	2013	→
High loading of polygenic risk for ADHD in children with comorbid aggression.	Hamshere ML et al.	—	2013	→
Highly impulsive rats: modelling an endophenotype to determine the neurobiological, genetic and environmental mechanisms of addiction.	Jupp B et al.	—	2013	→
High trans-ethnic replicability of GWAS results implies common causal variants.	Marigorta UM et al.	—	2013	→
ICD11 and DSM5: the Indian dilemma.	Jain S	—	2013	→
Identifying bipolar disorder susceptibility loci in a densely affected pedigree.	Collins AL et al.	—	2013	→
Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease.	Gratten J et al.	—	2013	→
Major channels involved in neuropsychiatric disorders and therapeutic perspectives.	Imbrici P et al.	—	2013	→
MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review.	Forstner AJ et al.	—	2013	→
Monozygotic twins affected with major depressive disorder have greater variance in methylation than their unaffected co-twin.	Byrne EM et al.	—	2013	→
Multiple variants aggregate in the neuregulin signaling pathway in a subset of schizophrenia patients.	Hatzimanolis A et al.	—	2013	→
Neuropsychological deficits in mice depleted of the schizophrenia susceptibility gene CSMD1.	Steen VM et al.	—	2013	→
New genes and new insights from old genes: update on Alzheimer disease.	Ringman JM et al.	—	2013	→
No association between catechol-o-methyltransferase Val108/158Met polymorphism and schizophrenia or its clinical symptomatology in a Mexican population.	Tovilla-Zárate C et al.	—	2013	→
Paying attention to all results, positive and negative.	Duncan LE	—	2013	→
Pharmacogenomics of bipolar disorder.	Severino G et al.	—	2013	→
Potential Impact of miR-137 and Its Targets in Schizophrenia.	Wright C et al.	—	2013	→
Psychiatric drug development: diagnosing a crisis.	Hyman SE	—	2013	→
Psychological correlates of handedness and corpus callosum asymmetry in autism: the left hemisphere dysfunction theory revisited.	Floris DL et al.	—	2013	→
Questions about DISC1 as a genetic risk factor for schizophrenia.	Sullivan PF	—	2013	→
Recent advances in quantitative neuroproteomics.	Craft GE et al.	—	2013	→
Repeated ketamine exposure induces an enduring resilient phenotype in adolescent and adult rats.	Parise EM et al.	—	2013	→
S100B overexpression increases behavioral and neural plasticity in response to the social environment during adolescence.	Buschert J et al.	—	2013	→
Schizophrenia at a genetics crossroads: where to now?	Corvin A	—	2013	→
Schizophrenia susceptibility and NMDA-receptor mediated signalling: an association study involving 32 tagSNPs of DAO, DAOA, PPP3CC, and DTNBP1 genes.	Sacchetti E et al.	—	2013	→
Selected rapporteur summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012.	Anderson-Schmidt H et al.	—	2013	→
Serotonin transporter gene: will epigenetics prove less depressing than genetics?	de Geus EJ et al.	—	2013	→
Targeted mutagenesis tools for modelling psychiatric disorders.	Deussing JM	—	2013	→
The evolutionary paradox and the missing heritability of schizophrenia.	van Dongen J et al.	—	2013	→
The genetics of alcohol dependence.	Rietschel M et al.	—	2013	→
The genetics of eating disorders.	Trace SE et al.	—	2013	→
The genomics of schizophrenia: update and implications.	Giusti-Rodríguez P et al.	—	2013	→
Using rodents to model schizophrenia and substance use comorbidity.	Ng E et al.	—	2013	→
What psychiatric genetics has taught us about the nature of psychiatric illness and what is left to learn.	Kendler KS	—	2013	→
Where GWAS and epidemiology meet: opportunities for the simultaneous study of genetic and environmental risk factors in schizophrenia.	McGrath JJ et al.	—	2013	→
Ankyrin 3: genetic association with bipolar disorder and relevance to disease pathophysiology.	Leussis MP et al.	—	2012	→
Assessment of relatedness between neurocan gene as bipolar disorder susceptibility locus and schizophrenia.	Oruč L et al.	—	2012	→
Autworks: a cross-disease network biology application for Autism and related disorders.	Nelson TH et al.	—	2012	→
Classifying psychosis--challenges and opportunities.	Gaebel W et al.	—	2012	→
DNA methylation in schizophrenia: progress and challenges of epigenetic studies.	Nishioka M et al.	—	2012	→
Emerging approaches for treatment of schizophrenia: modulation of cholinergic signaling.	Foster DJ et al.	—	2012	→
Rare variants in complex traits: novel identification strategies and the role of de novo mutations.	Jouan L et al.	—	2012	→
Revolution stalled.	Hyman SE	—	2012	→
The genes in the major histocompatibility complex as risk factors for schizophrenia: de omnibus dubitandum.	Lehner T	—	2012	→
The Minnesota Center for Twin and Family Research genome-wide association study.	Miller MB et al.	—	2012	→
A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.	Wang K et al.	—	2011	→