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cocaine phenotype

Aliases
CA, CD, CD-phenotype, COC, CoD, DSM dependence on cocaine, DSM-IV cocaine dependence, DSM‑IV CoD, addiction, addiction to cocaine, benzoylmethyl ecgonine, chronic cocaine, chronic cocaine use, cocaine, cocaine abuse, cocaine abuse/dependence diagnosis, cocaine abusers, cocaine addicted individuals, cocaine addiction, cocaine addicts, cocaine dependence, cocaine dependence severity, cocaine dependence symptoms, cocaine dependence treatment, cocaine dependent, cocaine dependent adults, cocaine dependent individuals, cocaine dependent patients, cocaine dependent persons, cocaine dependent subjects, cocaine exposure, cocaine group, cocaine reward, cocaine use, cocaine use disorder, cocaine users, cocaine-addicted, cocaine-addicted individuals, cocaine-addicted subjects, cocaine-dependent, cocaine-dependent individuals, cocaine-dependent patients, cocaine‑addicted, cocaine‑addicted brain, coke, dependence symptoms, indices of cocaine dependence severity, intravenous cocaine, powder cocaine, prenatal cocaine exposure, rewarding effects of cocaine, severity of cocaine dependence, smoked cocaine base, vulnerability to cocaine abuse
Evidence from: primary | all sources

Related entities (442)

SubjectRelationObjectp-valueEvidence
AA associated_with cocaine — 1
AA participants associated_with cocaine — 1
AA sample associated_with cocaine — 1
abstinence associated_with cocaine — 1
ACh associated_with cocaine — 1
addiction risk_factor_for cocaine — 1
ADHD associated_with cocaine — 1
ADHD protective_against cocaine — 1
adolescent rats interacts_with cocaine — 1
adolescents interacts_with cocaine — 1
African American risk_factor_for cocaine — 1
African American associated_with cocaine — 1
age of onset associated_with cocaine — 1
alcohol associated_with cocaine — 1
alcohol risk_factor_for cocaine — 2
alcohol protective_against cocaine — 1
alcohol dependence associated_with cocaine — 4
alcoholism associated_with cocaine — 1
alcohol self-administration associated_with cocaine — 1
Alcohol Use Disorder associated_with cocaine — 1
ALDH2 associated_with cocaine — 1
alpha expressed_in cocaine — 1
alternative splicing associated_with cocaine — 1
amygdala associated_with cocaine — 1
ANKK1 associated_with cocaine — 1
ANKK1 risk_factor_for cocaine — 1
anterior cingulate cortex associated_with cocaine — 2
antidepressants associated_with cocaine — 1
antisocial personality disorder associated_with cocaine — 1
antisocial personality disorder risk_factor_for cocaine — 1
associated SNPs associated_with cocaine — 1
AUDIT-C associated_with cocaine — 1
Bdnf risk_factor_for cocaine — 1
beta activity expressed_in cocaine — 1
bipolar disorder associated_with cocaine — 1
bipolar disorder risk_factor_for cocaine — 1
buprenorphine protective_against cocaine — 1
CACNB2 associated_with cocaine — 1
calcium channel risk_factor_for cocaine — 1
cannabis dependence associated_with cocaine — 1
cannabis use risk_factor_for cocaine — 1
carbamazepine associated_with cocaine — 1
CB1 receptor associated_with cocaine — 1
CB1 receptor regulates cocaine — 1
CB1 receptor interacts_with cocaine — 1
CB1 receptor risk_factor_for cocaine — 1
Cdk5 associated_with cocaine — 1
Cdk5 protective_against cocaine — 1
Cdk5 regulates cocaine — 1
cholinergic agonists targets cocaine — 1
Chrm5 interacts_with cocaine — 1
CHRNA risk_factor_for cocaine — 1
CHRNA10 risk_factor_for cocaine — 1
CHRNA2 risk_factor_for cocaine — 1
Chrna3 associated_with cocaine — 2
Chrna3 risk_factor_for cocaine — 1
Chrna4 risk_factor_for cocaine — 1
CHRNA5 risk_factor_for cocaine — 1
CHRNA5 associated_with cocaine — 2
Chrna6 risk_factor_for cocaine — 1
Chrna7 risk_factor_for cocaine — 1
CHRNA9 risk_factor_for cocaine — 1
Chrnb2 risk_factor_for cocaine — 1
Chrnb3 risk_factor_for cocaine — 1
Chrnb4 associated_with cocaine — 2
Chrnb4 risk_factor_for cocaine — 1
chronic cocaine abusers associated_with cocaine — 1
cocaine regulates acetylcholine — 1
cocaine regulates ADCY1 — 1
cocaine risk_factor_for addiction — 3
cocaine associated_with addiction — 1
cocaine associated_with ADHD — 1
cocaine associated_with age of onset — 1
cocaine interacts_with alcohol — 1
cocaine associated_with alcohol abuse — 1
cocaine associated_with alcohol dependence — 2
cocaine associated_with alcoholism — 1
cocaine associated_with alcohol self-administration — 2
cocaine regulates anandamide — 1
cocaine associated_with angiogenesis — 1
cocaine associated_with animals — 1
cocaine associated_with anterior cingulate cortex 0.05 2
cocaine regulates anterior cingulate cortex — 1
cocaine associated_with antisocial personality disorder — 2
cocaine associated_with apoptosis — 1
cocaine risk_factor_for attention deficit hyperactivity disorder — 1
cocaine regulates Bdnf — 1
cocaine regulates BEX4 — 1
cocaine associated_with bipolar disorder — 1
cocaine regulates BOLD signal — 1
cocaine risk_factor_for brain — 1
cocaine associated_with brain function — 1
cocaine risk_factor_for brain glucose metabolism — 1
cocaine associated_with brain structure — 1
cocaine associated_with brain volume — 1
cocaine risk_factor_for brain volume — 1
cocaine regulates CAMK2A — 1
cocaine regulates CamKII — 1
cocaine associated_with cannabis dependence — 1
cocaine regulates catecholamines — 1
cocaine associated_with caudate nucleus — 1
cocaine regulates Cdk5 — 2
cocaine associated_with cerebellum 0.05 1
cocaine regulates cerebral blood flow — 1
cocaine associated_with cerebral hemorrhage — 1
cocaine associated_with children — 1
cocaine associated_with cigarettes — 1
cocaine associated_with CNS dysfunction — 1
cocaine associated_with cocaine — 15
cocaine risk_factor_for cocaine — 9
cocaine associated_with cocaine self-administration — 3
cocaine associated_with cognition — 1
cocaine protective_against cognition — 1
cocaine risk_factor_for cognition — 1
cocaine associated_with conditioned place preference — 1
cocaine associated_with conditioned taste aversion — 1
cocaine associated_with controls — 1
cocaine associated_with countries — 1
cocaine risk_factor_for craving — 1
cocaine associated_with craving — 3
cocaine regulates CREB1 — 1
cocaine interacts_with CRF1R — 1
cocaine associated_with cue-induced reinstatement — 1
cocaine regulates DARPP-32 — 1
cocaine associated_with decision-making — 1
cocaine associated_with discovery sample — 1
cocaine regulates Dnmt3a — 1
cocaine interacts_with dopamine 0.001 6
cocaine targets dopamine — 1
cocaine associated_with dopamine — 1
cocaine regulates dopamine — 3
cocaine regulates Dopamine D2 receptor — 1
cocaine regulates dopamine efflux — 1
cocaine regulates dopamine level — 1
cocaine interacts_with Dopaminergic system — 1
cocaine interacts_with Dopamine transporter — 1
cocaine targets Dopamine transporter — 3
cocaine regulates dorsolateral prefrontal cortex — 1
cocaine risk_factor_for drug dependence — 1
cocaine associated_with drug dependence — 2
cocaine risk_factor_for drug-seeking behavior — 2
cocaine associated_with drug-seeking behavior — 3
cocaine associated_with DSM-IV — 1
cocaine protective_against emotional impairment — 1
cocaine associated_with EP300 — 1
cocaine associated_with errors of commission — 1
cocaine associated_with errors of omission — 1
cocaine regulates Fos — 2
cocaine regulates Fosb — 2
cocaine associated_with fractional anisotropy — 1
cocaine associated_with FTND — 1
cocaine regulates GABA — 1
cocaine interacts_with GABA — 2
cocaine regulates GABAergic genes — 1
cocaine expressed_in Gabbr1 — 1
cocaine regulates gene expression — 1
cocaine regulates glucose metabolism — 1
cocaine regulates GluR1 — 1
cocaine interacts_with glutamate — 1
cocaine regulates glutamatergic system — 1
cocaine regulates HDAC5 — 2
cocaine associated_with high — 2
cocaine interacts_with hippocampus — 1
cocaine regulates hippocampus — 1
cocaine expressed_in hippocampus — 1
cocaine associated_with hippocampus — 2
cocaine regulates HSD11B2 — 1
cocaine associated_with human brain — 1
cocaine risk_factor_for hyperlocomotion — 1
cocaine associated_with illicit drugs — 1
cocaine associated_with illicit drug use — 1
cocaine associated_with impulsivity — 1
cocaine associated_with infants — 1
cocaine associated_with inhibitory control — 1
cocaine associated_with insula — 1
cocaine regulates Jun — 1
cocaine regulates locomotor sensitization — 1
cocaine risk_factor_for locomotor sensitization — 1
cocaine regulates long-term depression — 1
cocaine associated_with loss of control — 1
cocaine associated_with major depressive disorder — 1
cocaine regulates Mapk1 — 1
cocaine associated_with MAPK3 — 1
cocaine interacts_with MAPK3 — 1
cocaine regulates MAPK3 — 1
cocaine interacts_with marijuana — 1
cocaine associated_with marijuana dependence — 1
cocaine associated_with maxdrinks — 1
cocaine associated_with midbrain — 1
cocaine interacts_with miRNA — 1
cocaine associated_with motivated behavior — 1
cocaine associated_with myocardial infarction — 1
cocaine associated_with nervousness — 1
cocaine associated_with neurogenesis — 1
cocaine associated_with Neuroimaging — 1
cocaine risk_factor_for neurological disorders — 1
cocaine associated_with nicotine — 2
cocaine regulates NMDA receptor — 1
cocaine interacts_with norepinephrine — 3
cocaine targets norepinephrine — 1
cocaine regulates NR1 — 1
cocaine regulates nucleus accumbens — 1
cocaine associated_with nucleus accumbens — 1
cocaine associated_with nucleus accumbens core — 1
cocaine regulates nucleus accumbens shell — 1
cocaine interacts_with nucleus accumbens shell — 1
cocaine associated_with nucleus accumbens shell — 1
cocaine interacts_with opiates — 1
cocaine associated_with opioid dependence — 3
cocaine associated_with other psychiatric disorders — 1
cocaine associated_with other substances — 1
cocaine risk_factor_for P300 amplitude — 1
cocaine risk_factor_for P300 latency — 1
cocaine associated_with P3a amplitude — 1
cocaine regulates Pdyn — 1
cocaine interacts_with PFC — 1
cocaine regulates PKA — 1
cocaine risk_factor_for Post-Traumatic Stress Disorder — 1
cocaine regulates PP1 — 1
cocaine targets prefrontal cortex — 2
cocaine interacts_with prefrontal cortex — 1
cocaine associated_with prefrontal cortex — 1
cocaine regulates prefrontal cortex — 1
cocaine regulates PRKACA — 1
cocaine associated_with protracted abstinence — 1
cocaine associated_with psychiatric disorders — 1
cocaine associated_with putamen — 1
cocaine associated_with radial diffusivity — 1
cocaine associated_with rats — 1
cocaine associated_with Reinforcing properties — 2
cocaine risk_factor_for relapse — 1
cocaine associated_with rewarding effects — 1
cocaine risk_factor_for reward sensitivity — 1
cocaine associated_with reward sensitivity — 1
cocaine associated_with reward system — 2
cocaine associated_with right cuneus — 1
cocaine associated_with right dorsolateral prefrontal cortex — 1
cocaine associated_with SAGE — 1
cocaine associated_with schizophrenia — 1
cocaine associated_with sedative dependence — 1
cocaine associated_with sensorimotor region — 1
cocaine interacts_with serotonin — 2
cocaine associated_with signal transduction — 1
cocaine regulates SLC6A2 — 1
cocaine associated_with smoking cessation — 1
cocaine risk_factor_for stereotypy — 1
cocaine associated_with stimulant dependence — 1
cocaine risk_factor_for stress response — 1
cocaine associated_with stress response — 1
cocaine associated_with striatum — 2
cocaine interacts_with striatum — 1
cocaine associated_with subcortical regions — 1
cocaine risk_factor_for substance abuse — 1
cocaine risk_factor_for substance use — 4
cocaine biomarker_for substance use — 1
cocaine associated_with substance use — 3
cocaine interacts_with suicide — 1
cocaine risk_factor_for suicide — 1
cocaine associated_with synaptic plasticity — 1
cocaine associated_with thalamus — 1
cocaine interacts_with tobacco use — 1
cocaine associated_with Twin cohort — 1
cocaine associated_with University of Pennsylvania — 1
cocaine interacts_with ventral striatum — 1
cocaine associated_with visual region — 1
cocaine associated_with wave 2 — 1
cocaine associated_with white matter — 1
cocaine associated_with withdrawal — 1
cocaine associated_with young adults — 2
cocaine group associated_with cocaine — 1
cocaine-induced paranoia associated_with cocaine — 2
cocaine use disorder associated_with cocaine — 2
cocaine withdrawal associated_with cocaine — 1
Collaborative Study on the Genetics of Alcoholism (COGA) associated_with cocaine — 1
COMT associated_with cocaine — 1
control subjects protective_against cocaine — 1
craving associated_with cocaine — 1
DBH protective_against cocaine — 1
DBH associated_with cocaine — 1
delay discounting risk_factor_for cocaine — 1
delay of gratification protective_against cocaine — 1
Dependence symptoms associated_with cocaine — 1
depression risk_factor_for cocaine — 1
depression associated_with cocaine — 1
DISC1 risk_factor_for cocaine — 1
discovery sample associated_with cocaine — 1
discrimination risk_factor_for cocaine — 1
disulfiram associated_with cocaine — 1
Dnmt3a associated_with cocaine — 1
Dnmt3a risk_factor_for cocaine — 1
dopamine risk_factor_for cocaine — 1
dopamine interacts_with cocaine — 2
dopamine associated_with cocaine — 3
dopamine agonists associated_with cocaine — 1
Dopamine D2 receptor biomarker_for cocaine — 2
Dopamine D2 receptor associated_with cocaine — 2
dopamine-related genes risk_factor_for cocaine — 1
Dopamine transporter regulates cocaine — 1
Dopamine transporter risk_factor_for cocaine — 1
DRD1 associated_with cocaine — 1
DRD3 associated_with cocaine — 2
DRD4 associated_with cocaine — 1
EA associated_with cocaine — 1
EA participants associated_with cocaine — 1
emotional abuse risk_factor_for cocaine — 1
endophenotype-general candidate SNPs associated_with cocaine — 1
EP300 associated_with cocaine — 1
European ancestry associated_with cocaine — 1
externalizing behavior associated_with cocaine — 1
FAM53B risk_factor_for cocaine — 1
Family study of cocaine dependence associated_with cocaine — 1
FA reduction biomarker_for cocaine — 1
FSCD associated_with cocaine — 3
FTND associated_with cocaine — 1
GABAergic genes expressed_in cocaine — 1
GABAergic genes associated_with cocaine 9.1e-14 1
GABAergic genes risk_factor_for cocaine — 1
GABARAP expressed_in cocaine — 1
Gabbr1 biomarker_for cocaine 0.013 3
GABRA2 associated_with cocaine — 1
GABRB1 expressed_in cocaine — 1
GABRB1 biomarker_for cocaine 0.044 1
Gabrg2 associated_with cocaine — 1
Gabrg2 expressed_in cocaine 0.03 1
Gabrg2 biomarker_for cocaine 0.021 2
GAD1 biomarker_for cocaine 0.013 1
GAD1 expressed_in cocaine — 1
GAD1 associated_with cocaine — 1
GAD2 biomarker_for cocaine 0.013 1
GAD2 expressed_in cocaine — 1
GAD2 associated_with cocaine — 1
ghrelin interacts_with cocaine — 1
glutamate targets cocaine — 1
Gphn biomarker_for cocaine 0.02 2
Gphn associated_with cocaine — 1
Gphn expressed_in cocaine — 1
GRIN2B biomarker_for cocaine — 1
GRIN2D biomarker_for cocaine — 1
GRM3 biomarker_for cocaine — 1
GWAS associated_with cocaine — 2
H3K4me3 biomarker_for cocaine — 1
heroin users associated_with cocaine — 2
hippocampus regulates cocaine — 1
HPA axis associated_with cocaine — 1
impulsivity associated_with cocaine — 1
income risk_factor_for cocaine — 1
independent samples associated_with cocaine — 1
insula associated_with cocaine — 1
ionotropic glutamate receptor expressed_in cocaine — 1
KCNT2 risk_factor_for cocaine — 1
Less educated risk_factor_for cocaine — 1
lithium associated_with cocaine — 1
M2 receptor protective_against cocaine — 1
major depressive disorder associated_with cocaine — 2
Mapk1 associated_with cocaine — 1
MAPK3 associated_with cocaine — 1
marijuana risk_factor_for cocaine — 1
marijuana protective_against cocaine — 1
marijuana dependence associated_with cocaine — 1
marital status risk_factor_for cocaine — 1
McLean Hospital associated_with cocaine — 1
medial frontal cortex associated_with cocaine — 1
medial orbitofrontal cortex associated_with cocaine — 1
Medical University of South Carolina associated_with cocaine — 1
MEG3 associated_with cocaine — 1
MEG3 biomarker_for cocaine — 1
Methadone protective_against cocaine — 1
mGluR5 associated_with cocaine — 1
midbrain associated_with cocaine — 1
mood disorders associated_with cocaine — 1
NCS1 associated_with cocaine — 1
NCS1 risk_factor_for cocaine — 2
nicotine associated_with cocaine — 2
nimodipine associated_with cocaine — 1
NRXN1 risk_factor_for cocaine — 1
NRXN1 associated_with cocaine — 1
NRXN3 associated_with cocaine — 1
nucleus accumbens associated_with cocaine — 1
opioid risk_factor_for cocaine — 1
opioid dependence associated_with cocaine — 1
Opioid system associated_with cocaine — 1
OPRK1 risk_factor_for cocaine — 1
OPRK1 associated_with cocaine — 1
orbitofrontal cortex associated_with cocaine — 1
overdose associated_with cocaine — 1
OXT protective_against cocaine — 1
oxytocin protective_against cocaine — 1
oxytocin interacts_with cocaine — 1
P300 amplitude biomarker_for cocaine — 1
P300 latency biomarker_for cocaine — 1
PAU PRS associated_with cocaine — 1
PKA associated_with cocaine — 1
Post-Traumatic Stress Disorder risk_factor_for cocaine — 1
Post-Traumatic Stress Disorder associated_with cocaine — 1
poverty associated_with cocaine — 1
P rats associated_with cocaine — 1
prefrontal cortex associated_with cocaine — 1
probands associated_with cocaine — 1
problematic alcohol use associated_with cocaine — 1
psychiatric disorders risk_factor_for cocaine — 1
psychiatric disorders associated_with cocaine — 1
rats interacts_with cocaine — 1
relationship status risk_factor_for cocaine — 1
roscovitine interacts_with cocaine — 1
rs1076560 risk_factor_for cocaine — 1
rs1076560 associated_with cocaine — 1
rs2283265 risk_factor_for cocaine — 1
rs6985606 associated_with cocaine — 1
rs997917 associated_with cocaine — 1
SAGE associated_with cocaine — 1
SDS associated_with cocaine — 1
sedative dependence associated_with cocaine — 1
severe alcohol use disorder risk_factor_for cocaine — 1
sex risk_factor_for cocaine — 1
SLC6A1 associated_with cocaine 0.05 1
SLC6A1 biomarker_for cocaine 0.05 1
SLC6A3 associated_with cocaine — 1
smoking associated_with cocaine 0.002 1
smoking phenotypes associated_with cocaine — 1
SNP associated_with cocaine — 1
SNP risk_factor_for cocaine — 1
Sprague-Dawley rats interacts_with cocaine — 1
stimulant dependence associated_with cocaine — 1
study cohort associated_with cocaine — 1
Study of Addiction: Genetics and Environment associated_with cocaine — 1
subcortical regions associated_with cocaine — 1
substance use associated_with cocaine — 4
substantia nigra biomarker_for cocaine — 1
tobacco use risk_factor_for cocaine — 1
tobacco use protective_against cocaine — 1
tolerance associated_with cocaine — 1
training set associated_with cocaine — 1
UHS associated_with cocaine — 1
unemployment risk_factor_for cocaine — 1
University of Connecticut Health Center associated_with cocaine — 1
Unmarried risk_factor_for cocaine — 1
Virginia Twin Registry associated_with cocaine — 1
white matter associated_with cocaine — 1
withdrawal associated_with cocaine — 2
Yale-Penn associated_with cocaine — 2
Yale–Penn cohort associated_with cocaine — 1
Yale University School of Medicine associated_with cocaine — 1

Mentioned in (322)

Papers in which this entity is mentioned.

Merged raw entities (52)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name Type Papers Mentions
cocaine drug 311 1480
cocaine dependence phenotype 51 165
prenatal cocaine exposure phenotype 33 128
cocaine addiction phenotype 25 52
cocaine abuse phenotype 11 12
cocaine abusers cohort 8 18
cocaine reward phenotype 8 14
cocaine addicts cohort 7 23
ca phenotype 3 6
cocaine addicts phenotype 3 9
chronic cocaine use phenotype 2 2
cocaine dependence severity phenotype 2 15
cocaine dependence symptoms phenotype 2 10
cocaine subjects cohort 2 8
cocaine abusers phenotype 1 1
cocaine dependence treatment phenotype 1 3
cocaine-dependent phenotype 1 1
cocaine-dependent patients phenotype 1 1
cocaine exposure phenotype 1 1
severity of cocaine dependence phenotype 1 1
addiction to cocaine phenotype — —
benzoylmethyl ecgonine phenotype — —
cd-phenotype phenotype — —
chronic cocaine phenotype — —
coc phenotype — —
cocaine phenotype — —
cocaine abuse/dependence diagnosis phenotype — —
cocaine-addicted phenotype — —
cocaine‑addicted phenotype — —
cocaine‑addicted brain phenotype — —
cocaine addicted individuals phenotype — —
cocaine-addicted individuals phenotype — —
cocaine-addicted subjects phenotype — —
cocaine dependent phenotype — —
cocaine dependent adults phenotype — —
cocaine dependent individuals phenotype — —
cocaine-dependent individuals phenotype — —
cocaine dependent patients phenotype — —
cocaine dependent persons phenotype — —
cocaine dependent subjects phenotype — —
cocaine group phenotype — —
cocaine users phenotype — —
cod phenotype — —
coke phenotype — —
dsm dependence on cocaine phenotype — —
dsm-iv cocaine dependence phenotype — —
dsm‑iv cod phenotype — —
indices of cocaine dependence severity phenotype — —
intravenous cocaine phenotype — —
powder cocaine phenotype — —
smoked cocaine base phenotype — —
vulnerability to cocaine abuse phenotype — —