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heavy drinking phenotype

Aliases
10+ cigarettes per day, 5 or more drinks in 24 hours, 5 or more drinks per occasion, >4 drinks in one day, Alcohol use, Alcohol-using teens, HE drinking, HED, HED frequencies, HED frequency, Heavy drinking, Heavy substance use, addicts, alcohol consumption, baseline HED, binge drinking, binge drinking (5+ drinks), case, dependent heroin users, diacetylmorphine, drink heavily, drinking behavior, drinking five or more drinks per occasion, drunk, ever drinking ≥5 drinks/day, excessive alcohol consumption, fairly heavy drinkers, frequency of heavy episodic drinking, health risk behaviors, heavier drinkers, heavier drinking, heavier use, heavy (10+ cigarettes/day), heavy alcohol consumption, heavy alcohol use, heavy cannabis use, heavy consumption, heavy drinker, heavy drinkers, heavy drinking, heavy drinking day, heavy drinking days, heavy drinking episodes, heavy drinking patterns, heavy episodic drinking, heavy episodic drinking occasion, heavy episodic drinking outcomes, heavy smoker, heavy smoker group, heavy smoker population, heavy smokers, heavy smoking group, heavy substance use, heavy tobacco use, heavy use, heavy vs never smoking, heroin, heroin addiction, heroin addicts, heroin dependence, heroin dependent, heroin dependent persons, heroin dependent population, heroin use disorder, heroin users, heroin-dependent, heroin-dependent cases, heroin-dependent individuals, heroine, high alcohol intake, higher alcohol intake, human daily heavy drinkers, illicit heroin, initial status of heavy episodic drinking, lifetime non-fatal overdose due to heroin, low levels of heavy drinking, lower levels of HED, nicotine dependence, non-treatment seeking heavy drinkers, opioid, opioid heroin, overdose requiring medical treatment, participants, participants with heavy alcohol use, patients, percentage of heavy drinking days, prolonged heavy drinking, regular heavy drinking, repeated heavy drinking episodes, smack, smoke heavily, use/dependence on heroin
Evidence from: primary | all sources

Related entities (295)

SubjectRelationObjectp-valueEvidence
10th graders associated_with heavy drinking — 1
5-HTTLPR risk_factor_for heavy drinking — 1
8th graders associated_with heavy drinking — 1
active lever pressing associated_with heavy drinking — 1
ADHD risk_factor_for heavy drinking — 2
ADHD associated_with heavy drinking — 1
adolescents associated_with heavy drinking — 2
adults associated_with heavy drinking — 1
adverse childhood experiences risk_factor_for heavy drinking — 1
African American associated_with heavy drinking — 1
age risk_factor_for heavy drinking — 1
age protective_against heavy drinking — 1
age at first drink risk_factor_for heavy drinking — 1
alcohol risk_factor_for heavy drinking — 3
alcohol associated_with heavy drinking — 6
Alcohol abstinence targets heavy drinking — 1
alcohol sensitivity associated_with heavy drinking — 2
alcohol sensitivity risk_factor_for heavy drinking — 1
alpha biomarker_for heavy drinking — 1
alternative splicing associated_with heavy drinking — 1
amygdala associated_with heavy drinking — 1
ANKK1 associated_with heavy drinking — 1
anterior cingulate cortex associated_with heavy drinking — 1
AUDIT associated_with heavy drinking — 1
AUDIT-C associated_with heavy drinking — 1
binge drinking associated_with heavy drinking — 1
black men associated_with heavy drinking — 1
buprenorphine protective_against heavy drinking — 1
candidate genes risk_factor_for heavy drinking — 2
case subjects associated_with heavy drinking — 1
caudate nucleus risk_factor_for heavy drinking — 1
children of alcoholic parents risk_factor_for heavy drinking — 1
cigarette tax protective_against heavy drinking — 1
Collaborative Study on the Genetics of Alcoholism (COGA) associated_with heavy drinking — 1
college attendance risk_factor_for heavy drinking — 1
Combine Study associated_with heavy drinking — 1
committed relationships protective_against heavy drinking — 1
COMT associated_with heavy drinking — 1
coping motives associated_with heavy drinking — 1
Crem associated_with heavy drinking — 1
CRF1R risk_factor_for heavy drinking — 1
dopamine interacts_with heavy drinking — 1
dopamine biomarker_for heavy drinking — 1
Dopamine D2 receptor associated_with heavy drinking — 1
dorsolateral prefrontal cortex associated_with heavy drinking — 1
DRD3 associated_with heavy drinking — 1
early alcohol use risk_factor_for heavy drinking — 1
early marriage risk_factor_for heavy drinking — 1
early pubertal timing risk_factor_for heavy drinking — 1
endophenotype-general candidate SNPs associated_with heavy drinking — 1
enhancement motives associated_with heavy drinking — 1
EP300 associated_with heavy drinking — 1
ethanol group associated_with heavy drinking — 1
European ancestry associated_with heavy drinking — 1
externalizing disorders risk_factor_for heavy drinking — 1
externalizing disorders associated_with heavy drinking — 1
EXT PGS associated_with heavy drinking 1.03e-05 1
EXT polygenic score associated_with heavy drinking — 1
female participants associated_with heavy drinking — 1
FH+ subjects risk_factor_for heavy drinking — 1
gabapentin protective_against heavy drinking 0.001 1
GABRA2 risk_factor_for heavy drinking — 1
GATA4 risk_factor_for heavy drinking — 1
genetic factors risk_factor_for heavy drinking — 1
glucose associated_with heavy drinking — 1
GRIN2A associated_with heavy drinking 0.0079 1
GRM8 risk_factor_for heavy drinking — 1
haplotype associated_with heavy drinking — 1
healthy controls associated_with heavy drinking — 1
heavy drinking associated_with 12th graders — 1
heavy drinking risk_factor_for academic performance — 1
heavy drinking interacts_with ACC — 1
heavy drinking associated_with acute withdrawal — 1
heavy drinking risk_factor_for addiction — 1
heavy drinking associated_with adolescent drinking — 1
heavy drinking associated_with adolescents — 2
heavy drinking associated_with AD symptom count — 1
heavy drinking associated_with AD symptoms — 2
heavy drinking expressed_in adulthood — 1
heavy drinking associated_with alcohol — 6
heavy drinking risk_factor_for alcohol dependence — 1
heavy drinking associated_with alcohol dependence — 1
heavy drinking risk_factor_for alcohol-related problems — 2
heavy drinking associated_with alcohol sensitivity — 1
heavy drinking associated_with Alcohol Use Disorder — 2
heavy drinking risk_factor_for Alcohol Use Disorder — 3
heavy drinking risk_factor_for alcohol use disorders — 3
heavy drinking risk_factor_for all-cause mortality — 1
heavy drinking interacts_with amygdala — 1
heavy drinking associated_with antisocial personality disorder — 1
heavy drinking associated_with AP — 1
heavy drinking associated_with at-risk groups — 1
heavy drinking risk_factor_for attention network — 1
heavy drinking associated_with AUD — 1
heavy drinking associated_with auditory — 1
heavy drinking associated_with binge drinking — 1
heavy drinking associated_with bipolar I disorder — 1
heavy drinking associated_with borderline personality disorder — 1
heavy drinking associated_with brain development — 1
heavy drinking associated_with cannabis use — 1
heavy drinking risk_factor_for cardiovascular disease — 1
heavy drinking associated_with cerebellar region — 1
heavy drinking associated_with cigarette tax — 1
heavy drinking associated_with Collaborative Study on the Genetics of Alcoholism (COGA) — 1
heavy drinking expressed_in college students — 1
heavy drinking risk_factor_for conduct disorder — 1
heavy drinking risk_factor_for corpus callosum — 1
heavy drinking associated_with corpus callosum — 1
heavy drinking associated_with craving — 3
heavy drinking protective_against craving — 1
heavy drinking regulates Crem 0.001 1
heavy drinking risk_factor_for death — 1
heavy drinking associated_with dependence — 1
heavy drinking associated_with depression — 1
heavy drinking risk_factor_for depressive symptoms — 1
heavy drinking risk_factor_for diabetes — 1
heavy drinking regulates dopamine — 1
heavy drinking interacts_with Dopaminergic system — 1
heavy drinking associated_with drug dependence — 2
heavy drinking associated_with early adulthood — 1
heavy drinking associated_with Error-related negativity amplitude — 1
heavy drinking associated_with ethanol consumption — 1
heavy drinking risk_factor_for executive functioning — 1
heavy drinking associated_with frontal cortex — 3
heavy drinking associated_with frontal pole — 1
heavy drinking associated_with heavy drinking — 6
heavy drinking risk_factor_for heavy drinking — 2
heavy drinking associated_with heroin users — 1
heavy drinking associated_with High school seniors — 1
heavy drinking associated_with impulsivity — 1
heavy drinking risk_factor_for inattentive ADHD — 1
heavy drinking risk_factor_for inflammation — 1
heavy drinking interacts_with insula — 1
heavy drinking associated_with major depressive disorder — 1
heavy drinking associated_with mandated students — 1
heavy drinking associated_with marital satisfaction — 1
heavy drinking associated_with medial prefrontal cortex — 1
heavy drinking associated_with medical consequences — 1
heavy drinking risk_factor_for medical problems — 1
heavy drinking risk_factor_for memory — 1
heavy drinking risk_factor_for memory problems — 1
heavy drinking risk_factor_for metabolic syndrome — 1
heavy drinking risk_factor_for morbidity — 1
heavy drinking risk_factor_for mortality — 1
heavy drinking risk_factor_for Neurocognitive deficits — 1
heavy drinking associated_with nicotine — 2
heavy drinking risk_factor_for non-communicable disease — 1
heavy drinking risk_factor_for non-fatal overdose — 1
heavy drinking associated_with occipital cortex — 1
heavy drinking associated_with older adults — 1
heavy drinking associated_with older cohort — 1
heavy drinking risk_factor_for opioid dependence — 2
heavy drinking associated_with opioid dependence 0.07 2
heavy drinking targets OPRM1 — 1
heavy drinking associated_with OPRM1 — 1
heavy drinking regulates orbitofrontal cortex — 1
heavy drinking interacts_with orbitofrontal cortex — 1
heavy drinking associated_with other substances — 1
heavy drinking associated_with P300 amplitude — 1
heavy drinking associated_with parental psychopathology — 1
heavy drinking associated_with parietal cortex — 1
heavy drinking associated_with polysubstance abuse — 1
heavy drinking associated_with poor mental health — 1
heavy drinking associated_with positive alcohol expectancies — 2
heavy drinking associated_with postmortem brain — 1
heavy drinking risk_factor_for prefrontal cortex 0.09 1
heavy drinking associated_with prefrontal cortex — 1
heavy drinking risk_factor_for prefrontal white matter — 1
heavy drinking risk_factor_for psychiatric disorders — 1
heavy drinking associated_with puberty — 1
heavy drinking interacts_with putamen — 1
heavy drinking interacts_with rats — 1
heavy drinking associated_with risk factor — 1
heavy drinking associated_with risky drinking — 1
heavy drinking associated_with sex — 1
heavy drinking risk_factor_for slower reaction times — 1
heavy drinking risk_factor_for smoking — 1
heavy drinking risk_factor_for smoking cessation — 1
heavy drinking associated_with specific phobia — 1
heavy drinking associated_with stop-signal reaction time — 1
heavy drinking risk_factor_for stressful life events — 1
heavy drinking associated_with striatum — 1
heavy drinking associated_with substance use — 2
heavy drinking risk_factor_for substance use — 2
heavy drinking associated_with substantia nigra — 1
heavy drinking associated_with thalamus — 1
heavy drinking interacts_with thalamus — 1
heavy drinking associated_with treatment samples — 1
heavy drinking associated_with United States — 1
heavy drinking associated_with usual quantity — 1
heavy drinking associated_with ventral tegmental area — 1
heavy drinking associated_with wave 2 — 1
heavy drinking risk_factor_for white matter — 1
heavy drinking risk_factor_for withdrawal — 1
heavy drinking associated_with young adults — 1
heavy drinking associated_with younger cohort — 1
High school seniors associated_with heavy drinking — 1
impulsivity risk_factor_for heavy drinking — 1
inactive lever pressing associated_with heavy drinking — 1
insula associated_with heavy drinking — 1
low LR risk_factor_for heavy drinking — 1
mandated students associated_with heavy drinking — 1
marijuana risk_factor_for heavy drinking — 1
married individuals protective_against heavy drinking — 1
married individuals associated_with heavy drinking — 1
medial prefrontal cortex associated_with heavy drinking — 1
men risk_factor_for heavy drinking — 1
Methadone interacts_with heavy drinking — 1
Methadone protective_against heavy drinking — 1
Methadone associated_with heavy drinking — 1
mothers protective_against heavy drinking — 1
nalmefene protective_against heavy drinking — 1
naltrexone protective_against heavy drinking — 2
NCAM1 associated_with heavy drinking 0.0003 1
negative mood risk_factor_for heavy drinking — 1
negative urgency risk_factor_for heavy drinking — 1
NESARC associated_with heavy drinking — 1
NESARC-III associated_with heavy drinking — 1
novelty seeking associated_with heavy drinking — 1
NTX protective_against heavy drinking — 1
older adults associated_with heavy drinking — 1
opiates risk_factor_for heavy drinking — 1
Oprd1 associated_with heavy drinking — 1
OPRM1 biomarker_for heavy drinking — 2
OPRM1 risk_factor_for heavy drinking — 2
OPRM1 targets heavy drinking — 1
OPRM1 protective_against heavy drinking — 1
OPRM1 A118G associated_with heavy drinking — 2
OPRM1 A118G protective_against heavy drinking — 1
OPRM1 A118G risk_factor_for heavy drinking — 3
orbitofrontal cortex associated_with heavy drinking — 1
oxytocin interacts_with heavy drinking — 1
oxytocin protective_against heavy drinking — 1
oxytocin risk_factor_for heavy drinking — 1
parental alcoholism risk_factor_for heavy drinking — 3
parental alcoholism associated_with heavy drinking — 1
parental divorce/separation associated_with heavy drinking — 1
parental divorce/separation risk_factor_for heavy drinking — 2
parental relationship discord risk_factor_for heavy drinking — 1
parental relationship discord associated_with heavy drinking — 1
Pde4b associated_with heavy drinking 0.0079 1
peer alcohol use associated_with heavy drinking — 1
peer alcohol use regulates heavy drinking — 1
peer substance use risk_factor_for heavy drinking — 1
PER1 associated_with heavy drinking — 1
physical abuse risk_factor_for heavy drinking — 1
polygenic risk score associated_with heavy drinking — 1
polygenic risk score protective_against heavy drinking — 1
polygenic risk score risk_factor_for heavy drinking — 1
Polygenic risk score for alcohol dependence associated_with heavy drinking — 1
Polygenic risk score for alcohol dependence risk_factor_for heavy drinking — 1
polysubstance abuse associated_with heavy drinking — 1
positive alcohol expectancies risk_factor_for heavy drinking — 1
Post-Traumatic Stress Disorder associated_with heavy drinking — 1
poverty risk_factor_for heavy drinking — 1
problems associated_with heavy drinking — 1
readiness to change protective_against heavy drinking — 1
rs1051730 associated_with heavy drinking — 1
rs1074287 risk_factor_for heavy drinking — 1
rs1074287 associated_with heavy drinking — 2
rs1344706 associated_with heavy drinking — 1
rs16969968 associated_with heavy drinking — 1
rs2236861 associated_with heavy drinking — 1
rs2236861 risk_factor_for heavy drinking — 1
rs279858 risk_factor_for heavy drinking — 1
rs279858 associated_with heavy drinking — 1
rs3778150 associated_with heavy drinking — 1
rs3778151 risk_factor_for heavy drinking — 1
rs3778151 associated_with heavy drinking — 1
rs510769 associated_with heavy drinking — 1
rs510769 risk_factor_for heavy drinking — 2
rs671 protective_against heavy drinking — 1
rs9829896 protective_against heavy drinking — 1
sex associated_with heavy drinking — 2
sex interacts_with heavy drinking — 1
SLC6A3 associated_with heavy drinking — 1
smoking behaviour associated_with heavy drinking — 1
SNP risk_factor_for heavy drinking — 1
SRE associated_with heavy drinking — 1
stressful life events risk_factor_for heavy drinking — 1
substance use risk_factor_for heavy drinking — 2
substance use associated_with heavy drinking — 1
tobacco use risk_factor_for heavy drinking — 1
topiramate protective_against heavy drinking — 1
TPH1 risk_factor_for heavy drinking — 1
TPH2 risk_factor_for heavy drinking — 1
TTC12 associated_with heavy drinking — 1
UHS associated_with heavy drinking — 1
UKB associated_with heavy drinking — 1
variant associated_with heavy drinking — 1
ventral striatum associated_with heavy drinking — 1
White men associated_with heavy drinking — 1
women protective_against heavy drinking — 1
young adults associated_with heavy drinking — 2
ZNF804A associated_with heavy drinking — 1

Mentioned in (275)

Papers in which this entity is mentioned.

Merged raw entities (86)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name Type Papers Mentions
heavy drinking phenotype 98 164
heroin drug 81 181
heavy drinkers cohort 33 44
heavy alcohol use phenotype 24 36
heavy alcohol consumption phenotype 22 29
heavy episodic drinking phenotype 20 98
heavy drinkers phenotype 19 22
heavy drinking drug 14 16
heroin dependence phenotype 13 30
heavy smokers phenotype 11 13
heroin addiction phenotype 9 37
heavy smokers cohort 7 21
heroin abuse phenotype 7 10
heavier drinking phenotype 5 10
heavy alcohol users cohort 5 5
heavy use phenotype 5 7
health risk behaviors phenotype 4 5
heavy drinking days phenotype 4 7
heavy substance use phenotype 4 5
hazardous drinking pattern phenotype 3 3
heavy consumption phenotype 3 4
heavy drinker phenotype 3 3
heavy drinking episodes phenotype 3 3
heavy smoker phenotype 3 3
heroin addicts cohort 3 6
heroin overdose phenotype 3 5
hazardous substance use phenotype 2 3
heaviness of alcohol consumption phenotype 2 2
heaviness of consumption phenotype 2 7
baseline hed phenotype 1 2
heavier drinkers phenotype 1 1
heroin dependent phenotype 1 1
heroin use disorder phenotype 1 1
overdose requiring medical treatment phenotype 1 1
percentage of heavy drinking days phenotype 1 2
prolonged heavy drinking phenotype 1 1
10+ cigarettes per day phenotype — —
>4 drinks in one day phenotype — —
5 or more drinks in 24 hours phenotype — —
5 or more drinks per occasion phenotype — —
addicts phenotype — —
alcohol-using teens phenotype — —
binge drinking (5+ drinks) phenotype — —
dependent heroin users phenotype — —
diacetylmorphine phenotype — —
drink heavily phenotype — —
drinking five or more drinks per occasion phenotype — —
drunk phenotype — —
ever drinking ≥5 drinks/day phenotype — —
fairly heavy drinkers phenotype — —
frequency of heavy episodic drinking phenotype — —
heavy (10+ cigarettes/day) phenotype — —
heavy drinking day phenotype — —
heavy episodic drinking occasion phenotype — —
heavy episodic drinking outcomes phenotype — —
heavy smoker group phenotype — —
heavy smoker population phenotype — —
heavy smoking group phenotype — —
heavy tobacco use phenotype — —
heavy vs never smoking phenotype — —
hed frequencies phenotype — —
hed frequency phenotype — —
he drinking phenotype — —
heroin phenotype — —
heroin addicts phenotype — —
heroin-dependent phenotype — —
heroin-dependent cases phenotype — —
heroin-dependent individuals phenotype — —
heroin dependent persons phenotype — —
heroin dependent population phenotype — —
heroine phenotype — —
human daily heavy drinkers phenotype — —
illicit heroin phenotype — —
initial status of heavy episodic drinking phenotype — —
lifetime non-fatal overdose due to heroin phenotype — —
lower levels of hed phenotype — —
low levels of heavy drinking phenotype — —
non-treatment seeking heavy drinkers phenotype — —
opioid phenotype — —
opioid heroin phenotype — —
participants with heavy alcohol use phenotype — —
regular heavy drinking phenotype — —
repeated heavy drinking episodes phenotype — —
smack phenotype — —
smoke heavily phenotype — —
use/dependence on heroin phenotype — —